ライフサイエンスコーパス: plasticity

1 e developmental constraints (adaptive growth plasticity).

2 oxygen and pH changes through heterotrophic plasticity.

3 development or experience-dependent synaptic plasticity.

4 fers from traditional models of postsynaptic plasticity.

5 ) expression, and ensures long-term synaptic plasticity.

6 in humans that may favor increased synaptic plasticity.

7 the genomic storage effect due to phenotypic plasticity.

8 o transient occlusion of additional LTP-like plasticity.

9 nsistent differences in behaviour and social plasticity.

10 ns, a function that requires marked synaptic plasticity.

11 lective means to enhance memory and synaptic plasticity.

12 lopment and its modification during synaptic plasticity.

13 ally modulates development, homeostasis, and plasticity.

14 gaining a fundamental understanding of brain plasticity.

15 simulations support the observed structural plasticity.

16 eptors and is involved in mediating synaptic plasticity.

17 mitogenesis, tumor suppression, and neuronal plasticity.

18 chanisms mediating behavioral and phenotypic plasticity.

19 centration, indicating some form of neuronal plasticity.

20 ity and the precision in structural synaptic plasticity.

21 unknown how achieving drug use affects this plasticity.

22 d characterize polymorphisms associated with plasticity.

23 Delta(9)-tetrahydrocannabinol occludes this plasticity.

24 ers arising from learning-dependent synaptic plasticity.

25 kinetics and regulate spatiotemporal tumour plasticity.

26 es and triple junctions due to their limited plasticity.

27 ced metabolic changes and preserved synaptic plasticity.

28 NMDA receptor-mediated hippocampal synaptic plasticity.

29 profoundly influence neural computation and plasticity.

30 neuroactive molecules and influence synaptic plasticity.

31 ortical system, similar to chemical synaptic plasticity.

32 obal cell-wide and pathway-specific synaptic plasticity.

33 iveness, and define its new role in synaptic plasticity.

34 apses and are critical for the expression of plasticity.

35 gene expression shows dominance rather than plasticity.

36 e role of M1R in tonic suppression of axonal plasticity.

37 -responsive genes related to skeletal muscle plasticity.

38 hereas removal of PNNs in adults reopens for plasticity.

39 ritic spines regulates spine development and plasticity.

40 defects in excitatory synaptic function and plasticity.

41 ered characterization of such conformational plasticity.

42 vican is a critical regulator of interneuron plasticity.

43 ely poor prognosis, may result from cellular plasticity.

44 rocircuit motif under spike timing-dependent plasticity.

45 t influence of these two factors on neuronal plasticity.

46 le of Crem in regulating striatal structural plasticity.

47 e ability to express presynaptic homeostatic plasticity, a fundamental and adaptive form of NMJ plast

48 r transcription factors, suggesting that the plasticity accommodated by certain regulatory factors is

49 le an increasing number of studies show that plasticity across generations (transgenerational plastic

50 ules that govern activity-dependent synaptic plasticity, addictive drugs can derail the experience-dr

51 he hybrid phenotype contributes to metabolic plasticity, allowing cancer cells to adapt to various mi

52 utes to both the excitability and short-term plasticity alterations that we observed.

53 ological, electrophysiological, and synaptic plasticity alterations.

54 Notably, we uncovered cell state plasticity and adhesion dynamics regulated by Ror2, whic

55 nal changes, restores MeCP2 levels and spine plasticity and ameliorates cognitive defects in IL-1R8 K

56 Protist reproduction rate, morphological plasticity and cell speed were most important in determi

57 information on genetic variation, phenotypic plasticity and climatic niche modeling to evaluate plant

58 antly, these data suggest that developmental plasticity and connectivity are impaired in sensory syst

59 me populations exhibiting remarkable dietary plasticity and consuming high levels of moss, which is e

60 However, the relationship between spine plasticity and craving remains unclear.

61 ecification, the embryo temporally modulates plasticity and creates a time window during which each c

62 rve as a platform to decode cancer metabolic plasticity and design cancer therapies targeting metabol

63 The plasticity and endothermicity during deformation of MOFs

64 e dynamic structures which regulate neuronal plasticity and have crucial roles in myriad brain functi

65 ic progression, this study characterized the plasticity and heterogeneity of prostate cancer cells wi

66 Synaptic plasticity and homeostatic regulation of synapses is est

67 hat nonmating behaviors drive AOB inhibitory plasticity and indicate that increased MC inhibition inv

68 TD and is involved in many forms of synaptic plasticity and learning and memory.

69 w of CaMKII activation required for synaptic plasticity and learning.

70 precursor (MP) cells maintain developmental plasticity and longevity to provide long-term immunity w

71 is nutrient-sensing pathway in developmental plasticity and metabolic homeostasis.

72 systems as well as abnormalities in synaptic plasticity and neural connectivity, are currently sugges

73 T2CR in the BLA plays a critical role in CeA plasticity and neuropathic pain behaviors in the rat spi

74 These results reveal a capacity for neural plasticity and recovery that is larger than anything pre

75 ative response through the induction of cell plasticity and stemness.

76 FGF signaling acts to suppress cardiomyocyte plasticity and to preserve the integrity of the ventricu

77 cause of the potential to explore phenotypic plasticity and, specifically, how demographic and ecolog

78 t of the body axis, cell migration, synaptic plasticity, and a vast range of other biological process

79 ecent empirical studies of transgenerational plasticity, and find that they do not consistently suppo

80 f chromatin regulators in brain development, plasticity, and gene expression, thereby answering funda

81 Thus, basal synaptic strength, short-term plasticity, and homeostasis are determined input-specifi

82 aller cell size, a high degree of phenotypic plasticity, and increased protrusive activity emerge as

83 mediating an inhibition of synapse assembly, plasticity, and learning.

84 f AMPARs, necessary for synaptic hippocampal plasticity, and memory recall.

85 trophic factor (GDNF) promotes the function, plasticity, and survival of midbrain dopaminergic neuron

86 nic including context dependency, signalling plasticity, and tumour heterogeneity, and we offer a per

87 isms by which it controls vesicle fusion and plasticity are not well understood.

88 ted mechanisms underlying electrical synapse plasticity are similar to those that induce plasticity a

89 Our data establish rRNA 2'-O-Me plasticity as a mechanism providing functional specifici

90 demonstrate the potential to activate latent plasticity as a novel therapeutic strategy to restore sy

91 anaria), which show extensive seasonal vocal plasticity as adults.

92 Macrophages exhibit phenotypic plasticity, as they have the ability to switch their fun

93 er, these experiments reveal a novel type of plasticity at CA1 hippocampal synapses that is expressed

94 plasticity are similar to those that induce plasticity at chemical synapses, and offer the possibili

95 enerally fail by early cracking with limited plasticity at room temperature, which limits their malle

96 l changes during activity-dependent synaptic plasticity at the Drosophila neuromuscular junction.

97 timuli as a consequence of dopamine-mediated plasticity at the Kenyon cell-MBONalpha'3 synapse.

98 dies was typically an indirect assessment of plasticity at the neural level.

99 e, we analyzed events of structural synaptic plasticity at the single-synapse level after distinct pa

100 in mature axons may play a role in synaptic plasticity, axonal arborization, or functional diversity

101 bulb (AOB) is a site of experience-dependent plasticity between excitatory mitral cells (MCs) and inh

102 eurons, indicating differential drug-induced plasticity between the variants.

103 Phenotypic plasticity, both within and across generations, is an im

104 racemase after CCI injury improved synaptic plasticity, brain oscillations, and learning behavior.

105 reprogramming not only promotes cancer cell plasticity, but also provides novel insights for treatme

106 train and does not contribute to short-term plasticity, but induces a steady-state, asynchronous pos

107 AKT is indirectly implicated in synaptic plasticity, but its direct role has not been studied.

108 in mediating several forms of use-dependent plasticity, but the mechanisms by which it controls vesi

109 ributes to neuropathic-pain-related amygdala plasticity by driving synaptic excitation of CeA neurons

110 nd slices, we triggered a unique form of AIS plasticity by selectively targeting M-type K(+) channels

111 ired for long-term functional and structural plasticity changes.

112 ocular deprivation is the canonical model of plasticity confined to a critical period.

113 aths to fully understand how myelinated axon plasticity contributes to neuronal circuit formation and

114 se findings suggest that modulation of brain plasticity could be a major contribution to the antidepr

115 indow, revealing asymmetries in its size and plasticity depending on the leading input: auditory-visu

116 Phenotypic plasticity describes the phenotypic variation of a trait

117 dominant source of variability is phenotypic plasticity during development and adult life.

118 Synaptic plasticity (e.g., long-term potentiation [LTP]) is consi

119 y demonstrated that spinal respiratory motor plasticity elicited by acute intermittent hypoxia is enh

120 ence, we propose that spike timing-dependent plasticity enables this microcircuit motif to perform a

121 Crystal-plasticity finite-element simulations were employed to q

122 neuroscientific understanding of cross-modal plasticity following cochlear implantation has been rest

123 s failed to exhibit the necessary phenotypic plasticity for adapting to temporal changes at multiple

124 ct expression patterns and roles in synaptic plasticity for AKT isoforms in the hippocampus.

125 cuss the implications of GPCR conformational plasticity for drug design.

126 Furthermore, plasticity forms involve selective recruitment of previo

127 e useful tools for characterizing short-term plasticity from multi-electrode spike recordings in vivo

128 synaptic efficacy, including heterosynaptic plasticity, gain control, output balancing, activity nor

129 gulate transcription of Dlg4/PSD95, or other plasticity genes, are largely unknown, limiting the deve

130 ., network oscillations) and sleep-dependent plasticity has been difficult.

131 rically homeostatic but their stoichiometric plasticity has rarely been examined, particularly in ter

132 The study of brain plasticity has tended to focus on the synapse, where wel

133 mechanisms underlying spike-timing-dependent plasticity have been studied extensively in vitro Recent

134 ough LTM is sustained by structural synaptic plasticity, how synapses integrate spaced stimuli and de

135 individual differences in behaviour, social plasticity (i.e., individuals adjusting their behaviour)

136 In this context, we discuss how this plasticity, i.e. the capacity to adapt to demands encoun

137 VNS paired with experience can drive neural plasticity in a controlled and therapeutic direction.

138 le phenotypes and two measures of phenotypic plasticity in a maize nested association mapping (US-NAM

139 roving manual skills is mediated by synaptic plasticity in a region of motor cortex that, before lesi

140 rk exposure (DE) reactivates critical period plasticity in adults.

141 Enriched environments elicit brain plasticity in animals.

142 e results might reveal generic mechanisms of plasticity in cognitive networks and inform models of la

143 etics to examine whether changes in synaptic plasticity in D1- versus D2-MSN GABAergic synapses in th

144 all lack of changes in synaptic function and plasticity in DBN deficient mice may indicate robust com

145 , and the regulation and function of adipose plasticity in development and physiology can be explored

146 We link structure to plasticity in disordered solids via a microscopic struct

147 formation to the amygdala complex, and local plasticity in excitatory basolateral amygdala principal

148 haliana plants to herbivory and investigated plasticity in germination and defence phenotypes in thei

149 thermophila CBM64, in particular, displayed plasticity in its capacity to bind both crystalline and

150 nd of the period of heightened visual cortex plasticity in juveniles, whereas removal of PNNs in adul

151 us (DG) granule cell reactivity and synaptic plasticity in naive and in MDA-kindled anaesthetised rat

152 m depression (tLTD), the predominant form of plasticity in naive male mice, to spike-timing-dependent

153 lls revealed effects on neurodevelopment and plasticity in neural, immune, and endocrine networks.

154 ese data reveal that cocaine-evoked synaptic plasticity in PL-mPFC is reversible in vivo, and suggest

155 thermal local adaptation, but a presence of plasticity in populations experiencing contrasting condi

156 usly controls cellular and synaptic forms of plasticity in PV+ cells by regulating the localization o

157 Here, we show direct plasticity in recordings of neuronal populations in awak

158 indings suggest chimpanzees exhibit cortical plasticity in regions of the brain that were central to

159 te that neuron-derived E2 modulates synaptic plasticity in rodent BLA sex-dependently.

160 th shoot-root coordination and developmental plasticity in shaping organ biomass and architecture.

161 Vocal learning and social context-dependent plasticity in songbirds depend on a basal ganglia circui

162 ion as a regulator of circuit-level neuronal plasticity in the adult retina.

163 erine-mediated N-methyl-D-aspartate receptor plasticity in the amygdala and how this system could con

164 ur results support the idea that cross-modal plasticity in the case of early sensory deprivation rela

165 erning bidirectional synaptic and behavioral plasticity in the CNS.

166 This plasticity in the degree to which learned vocalizations

167 n the induction of functional and structural plasticity in the hippocampus.

168 we developed the working model that synaptic plasticity in the nucleus accumbens is central to age-re

169 d the role of JAK2/STAT3 in ketamine-induced plasticity in the OFC.

170 to small RNA levels at the source, allowing plasticity in the positioning of a target gene expressio

171 ects of 30 PTDH3 polymorphisms on expression plasticity in the same environments provided evidence of

172 Here, we tested the hypothesis that inducing plasticity in the spinal cord during chronic stroke coul

173 By inducing activity-dependent plasticity in the visual cortex of adult rats while reco

174 Both robustness and plasticity in this higher order property of atrichoblast

175 ged mice identifies a novel form of synaptic plasticity in VTA GABA cells, and the synaptic remodelin

176 ifies a novel form of glutamatergic synaptic plasticity in VTA GABA neurons, a currently understudied

177 city, a fundamental and adaptive form of NMJ plasticity in which perturbation to postsynaptic neurotr

178 ion of gene transcription can influence MPhi plasticity in wounds.

179 -ODP) and potentiation component (Pc-ODP) of plasticity independently.

180 ort a new phenomenon of sub-Tg, solid-state, plasticity-induced bonding; where amorphous polymeric fi

181 acellular recording, we monitored inputs and plasticity-inducing complex spikes (CSs) in CA1 neurons

182 ble debate on the degree to which phenotypic plasticity, introgressive hybridization and incomplete l

183 This functional plasticity involves a precise orchestration of gene expr

184 ty.SIGNIFICANCE STATEMENT Long-term synaptic plasticity is a fundamental property of the brain, causi

185 at the Abeta-mediated impairment of synaptic plasticity is accompanied by presynaptic effects that di

186 o sensorimotor recovery, but this structural plasticity is also limited to the first few weeks after

187 We found that PN-KC synaptic plasticity is crucial in controlling the generalization-

188 In contrast, mGluR-dependent plasticity is independent of calcium entry or calcium dy

189 These data indicate that MC-IGC plasticity is induced after male-male social chemosensor

190 The concept of neutrophil plasticity is new and, to our knowledge, these data are

191 ICANCE STATEMENT Activity-dependent neuronal plasticity is the cellular basis for learning and memory

192 Hebbian plasticity is thought to require glutamate signalling.

193 To our knowledge, this vascular plasticity is unique among mammalian tissues, and we exp

194 Input-timing-dependent plasticity (ITDP) is a circuit-based synaptic learning r

195 at signaling pathways involved in structural plasticity likely underlie this form of translation-inde

196 cient neurons also lack homeostatic synaptic plasticity, likely due to reduced levels of EEA1, a prot

197 rons and astrocytes, and ultimately synaptic plasticity loss evident by a decreased long-term potenti

198 inje cell synapse and induction of long-term plasticity (LTP) in M1, leading to transient occlusion o

199 ) activity, and increased levels of synaptic plasticity markers including brain derived neurotrophic

200 c alterations in CREB signaling and synaptic plasticity may underlie certain nicotine withdrawal phen

201 andidate genes for mean phenotype values and plasticity measures form structurally and functionally d

202 Synaptic scaling is a key homeostatic plasticity mechanism and is thought to be involved in th

203 together, our study outlines a morphological plasticity mechanism for dynamically fine-tuning AP cond

204 is study reveals physiological correlates of plasticity mechanisms of interval timing that take place

205 codes for a seasonally selected trait and a plasticity modifier locus that modulates the effects of

206 This plasticity occurs at the level of cortical maps and indi

207 Experience-dependent synaptic plasticity occurs on DA neurons while an organism is eng

208 origin of bipotent liver progenitors or the plasticity of cellular constituents comprising these tum

209 Here we report that RIN1 controls the plasticity of cultured mouse hippocampal neurons.

210 novel system for mechanistic analysis of the plasticity of developing neural circuits by showing that

211 Furthermore, the plasticity of electrical synapses may play an important

212 rating spiking activity-dependent short-term plasticity of electrical synapses.

213 However, the cell fate plasticity of endogenous pericytes in vivo remains uncle

214 We show that, in vivo, short-term plasticity of excitatory inputs to CA3 pyramidal cells c

215 is is achieved through rapid transcriptional plasticity of genes that have duplicated during aphid ev

216 ting preserved impact of Cav-1 on structural plasticity of hippocampal neurons with age.

217 as IL-12 and IL-23, have been shown to shape plasticity of ILCs, little is known about how the tissue

218 rhodensis is an ideal model for studying the plasticity of meiosis and how it can be modulated.

219 Plasticity of myelination represents a mechanism to tune

220 butes to the differentiation, maturation and plasticity of neurons.

221 Given the well-described plasticity of perivascular cells, we hypothesized that p

222 oidization in C. bursa-pastoris enhanced its plasticity of response to light and temperature, and all

223 dendritic complexity in the development and plasticity of sensory pathways.

224 not vitally contribute to the generation and plasticity of Th17 cells, but rather promoted the expans

225 city of the substrate binding pocket and the plasticity of the amino acids surrounding the allyl grou

226 ng, unfolding, misfolding and conformational plasticity of the high-efficiency frameshifting double m

227 conv and Treg cells highlight the functional plasticity of the NF-kappaB signaling pathway and unders

228 morphological criteria is difficult due the plasticity of these characteristics and the absence of s

229 The phenotypic plasticity of these traits was quantified as the relativ

230 ition by the IL-10R family and highlight the plasticity of type III interferon signaling and its ther

231 es and provides insights into the structural plasticity of ubiquitin-conjugating enzymes.

232 c pathology and improved axonal and synaptic plasticity on ventral horn motor neurons.

233 Plasticity onset was restored by a homeoprotein Otx2, wh

234 int between regimes dominated by associative plasticity or by synaptic homeostasis.

235 oth groups of species show little phenotypic plasticity or potential for evolutionary change in toler

236 ticity across generations (transgenerational plasticity or TGP) may occur, we have limited understand

237 ck a change in the optimum timing either via plasticity or via adaptation.

238 ise level of 20%, the model with nonspecific plasticity outperforms the standard, specific model.

239 Whereas, occlusion of LTP-like plasticity over M1 occurred only during late, but not ea

240 between evolutionary forces of rigidity and plasticity over transcriptional regulatory programs.

241 euronal excitability and short-term synaptic plasticity-parameters that critically govern neural circ

242 w the tissue microenvironment influences the plasticity, phenotype, and function of these cells.

243 evidence supports the idea that cancer cell plasticity promotes metastasis and tumor recurrence, res

244 leads to an unusual level of microstructural plasticity, raising the question of whether this contrib

245 cluding cognitive decline, impaired synaptic plasticity, reduced sociability, hyperactivity and incre

246 ketamine increased expression of the neural plasticity-related protein Arc, and this was prevented b

247 g the influence of experience on interneuron plasticity remain poorly understood.

248 nisms and behavioral conditions driving this plasticity remain unclear.

249 pike patterns could drive long-term synaptic plasticity remained unknown.

250 ure of the corrective bias from LMAN given a plasticity rule in RA.

251 e images are formed at the level of synaptic plasticity rules, cells, and circuits.

252 developmental time when experience-dependent plasticity shapes such circuits.

253 s of the weight dependence of heterosynaptic plasticity shifted their operating point between regimes

254 excitability and altered short-term synaptic plasticity.SIGNIFICANCE STATEMENT Schizophrenia is a pro

255 tudies have described spike-timing-dependent plasticity (STDP) at a synapse: the connection from neur

256 cur through a form of spike-timing-dependent plasticity (STDP) at the cerebellar inputs stage.

257 xperimentally derived spike-timing-dependent plasticity (STDP) rules, suggesting that STDP is key to

258 Spike timing-dependent synaptic plasticity (STDP) serves as a key cellular correlate of

259 icacy of rehabilitation can be increased by 'plasticity-stimulating' treatments that enhance experien

260 ophysiology of schizophrenia and in neuronal plasticity suggests that facilitation of NMDAR function

261 oth high mean phenotype values and levels of plasticity that are appropriate for the target performan

262 nal lineages, aided by mechanisms of genetic plasticity that contribute to uptake of genes associated

263 itions, as well as family-specific heritable plasticity that could facilitate adaptive change.

264 ynaptic facilitation is a form of short-term plasticity that enhances synaptic transmission for less

265 n (pLTF), a form of spinal respiratory motor plasticity that improves breathing in models of spinal c

266 a novel form of activity-dependent intrinsic plasticity that persistently eliminates the burst firing

267 ings reveal a novel framework of presynaptic plasticity that radically differs from traditional model

268 Plasticity that results from tetanization of input fibre

269 development and contribute to the epigenetic plasticity that underlies malignant transformation.

270 ulation (massed) induced structural synaptic plasticity, the same amount of stimulation divided in th

271 onal function through spike timing-dependent plasticity: The capability to disentangle superimposed f

272 -independently for mean phenotype values and plasticity, thereby generating varieties with both high

273 The nonspecific plasticity these neuromodulators may induce at neighbori

274 ow that, in the absence of noise, leakage of plasticity to adjacent synapses degrades the recognition

275 ual snail to spread by adaptive evolution or plasticity to different environments.

276 coincidence detection window during Hebbian plasticity to facilitate associative synaptic potentiati

277 Neural systems use homeostatic plasticity to maintain normal brain functions and to pre

278 over, our studies show that SCs retain their plasticity to myelinate and remodel myelin via mTORC1 th

279 ut the molecular mechanisms that enable such plasticity to occur.

280 -channel activity rapidly trigger unique AIS plasticity to stabilize network excitability.

281 ronment in vivo, Th22 cells displayed marked plasticity toward IFN-gamma production.

282 A transformation-induced plasticity (TRIP) assisted HEA with composition Fe50Mn30

283 estrogen receptor alpha (ERalpha) show great plasticity under the control of hormones and endocrine t

284 s of microstimulation to correct maladaptive plasticity underlying dysfunctional decision-making rela

285 achieving cocaine use reversed the synaptic plasticity underpinning the motivation to seek the drug.

286 sociation analysis on these traits and their plasticity, using 45,608 high-quality single-nucleotide

287 Since crystal plasticity varies systematically with imposed conditions

288 kappaB signaling decreased cortical synaptic plasticity via HDAC2.

289 To test this hypothesis, visual cortical plasticity was assessed in Ts65Dn mice that harbor a chr

290 Plasticity was estimated to accommodate, on average, a +

291 we show that initiation of ocular dominance plasticity was impaired with reduced CS, using mice lack

292 imulation remained constant, indicating that plasticity was not induced at the level of the periphery

293 urther, the magnitude of atDCS-induced local plasticity was related to baseline functional network st

294 This pattern of plasticity was specific to the gamma band as lower frequ

295 To study restriction of plasticity, we ectopically expressed C. elegans CHE-1, a

296 To relate these results to synaptic plasticity, we simulated a network of oscillators incorp

297 eptor signalling in ischaemia-induced neural plasticity, we subjected C3a receptor-deficient mice, GF

298 te it, its relationship to within-generation plasticity (WGP) and its role in evolutionary potential.

299 ages, and demonstrate the brain's remarkable plasticity, where language experience can change neural

300 nsity is not constant but, instead, exhibits plasticity with long-term endurance training.

301 through selective recruitment and structural plasticity within the receptor-binding site.