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1 activation of the receptor tyrosine kinases, platelet-derived and epidermal growth factor receptors.
2 increased sensitivity to neutrophil killing, platelet-derived antimicrobials in serum, and the cathel
7 endothelial cell-derived exosomes (EDEs) and platelet-derived exosomes (PDEs) were precipitated and e
11 ly suppressed cargo protein levels of plasma platelet-derived exosomes without altering total levels
14 individual completely devoid of plasma- and platelet-derived factor V (FV) identified 167 variants i
17 l clipping if animals had greater than 2% of platelets derived from 2bF8LV-transduced hCB cells, wher
18 onor platelets, we found marked differences: platelets derived from infused megakaryocytes closely re
21 In marked contrast, release of the patient's platelet-derived FV/Va (7% of normal) following platelet
23 l, thereby highlighting the critical role of platelet-derived FV/Va in ensuring hemostatic competence
24 expression in human platelets and that human platelet-derived FVIII can improve hemostasis in hemophi
26 early to initiate neovessel formation while platelet-derived GF (PDGF-BB) is needed later to stabili
27 tion of matrix-associated GFs, TGF-beta, and platelet-derived GF to GF(-) or culture supernatants.
32 oma cells, including increased expression of platelet derived growth factor receptor beta (PDGFRB) me
33 ent of known imatinib targets including Abl, platelet derived growth factor receptor beta (PDGFRbeta)
35 is a milieu of bioactive factors, including platelet derived growth factor, transforming growth fact
36 ession of the spliced XBP1 or treatment with platelet derived growth factor-BB up-regulated miR-150 e
37 tors such as tumor necrosis factor-alpha and platelet derived growth factor-BB were also found to inc
41 to delineate the transcriptional response to platelet-derived growth factor (PDGF) and fibroblast gro
42 rum response factor (SRF) is induced by both platelet-derived growth factor (PDGF) and fibroblast gro
45 e involved in the lipopolysaccharide-induced platelet-derived growth factor (PDGF) and Wnt signaling
46 10030 (Fovista; Ophthotech, New York, NY), a platelet-derived growth factor (PDGF) antagonist, admini
48 d apoptotic priming, we examined the role of platelet-derived growth factor (PDGF) in CAF priming for
50 rowth factors, the most representative being platelet-derived growth factor (PDGF) isoforms (PDGF-AA,
52 ied KCE method to an experimental model of a platelet-derived growth factor (PDGF) protein and its DN
57 ascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors, has sin
58 -of-function alterations leading to enhanced platelet-derived growth factor (PDGF) signaling are comm
61 ng a small interfering RNA (siRNA) targeting platelet-derived growth factor (PDGF) was used to allevi
63 clotted wound by a concentration gradient of platelet-derived growth factor (PDGF), together with oth
67 EDE levels of VCAM-1, von Willebrand factor, platelet-derived growth factor (PDGF)-BB, angiopoietin-1
69 angiogenic factors, friend of Gata 2 (FOG2), platelet-derived growth factor (PDGF)-beta, and phosphat
71 e discovery of a novel ligand for PDGFRbeta, platelet-derived growth factor (PDGF)-DD, opened the pos
73 d quiescent mesenchymal cell activation in a platelet-derived growth factor (PDGF)-dependent manner.
75 ells (HASMCs); effect of Sema3E on basal and platelet-derived growth factor (PDGF)-induced proliferat
77 or small interfering RNA knockdown decreased platelet-derived growth factor (PDGF)-mediated migration
80 EC was uniformly inhibited by combined VEGF/platelet-derived growth factor (PDGF)/FGF receptor inhib
81 ular endothelial growth factor (VEGF) and 2) platelet-derived growth factor (PDGF-BB) in gingival cre
82 rCS3 binds the nerve growth factor (NGF) and platelet-derived growth factor (PDGF-BB), but the functi
84 idence of and accelerated the development of platelet-derived growth factor -induced glioma in mice.
86 r receptor alpha (PDGFRalpha) and its ligand platelet-derived growth factor A (PDGF-A) are co-express
91 s (angiopoietin 2; hepatocyte growth factor; platelet-derived growth factor AA and BB; placental grow
92 tor, vascular endothelial growth factor, and platelet-derived growth factor AB) before and after comp
95 1, and transiently suppressed myofibroblast platelet-derived growth factor alpha differentiation mar
96 a similar level of TNF-alpha, TGF-beta1, and platelet-derived growth factor alpha genes, and a high l
97 recursor activity in embryos was confined to platelet-derived growth factor alpha(+), myogenic factor
98 cts with HEUS and in untreated subjects with platelet-derived growth factor alpha-negative HES (n = 2
99 ynthesis, which required the late release of platelet-derived growth factor and COX-2 mRNA stabilizat
102 morphogen sonic hedgehog (Shh) is driven by platelet-derived growth factor B (PDGF-BB) in vascular s
103 ar endothelial growth factor A (VEGF-A), and platelet-derived growth factor B chain (PDGF-BB), to sti
104 nd AKT and compared them to oligodendroglial platelet-derived growth factor B-induced tumors in Ctv-a
105 h, we demonstrate that two of these pathways-platelet-derived growth factor BB (PDGF BB) and neural p
107 ed a fibronectin peptide (P12) that can bind platelet-derived growth factor BB (PDGF-BB) and promote
109 ulated by ECFC-derived paracrine factors via platelet-derived growth factor BB (PDGF-BB)/platelet-der
110 study participants, the angiogenic cytokine platelet-derived growth factor BB glycoprotein correlate
113 nds to the transmembrane domain (TMD) of the platelet-derived growth factor beta receptor (PDGFbetaR)
114 d cells by forming a stable complex with the platelet-derived growth factor beta receptor transmembra
115 nteract with the transmembrane domain of the platelet-derived growth factor beta-receptor and specifi
118 phages, T cells, and platelets and increased platelet-derived growth factor D, Pdgfrb, Itga2, and mat
120 cell neuroprotection, with factors from the platelet-derived growth factor family being the most pot
121 f activated T cells, epidermal growth factor/platelet-derived growth factor family members, Wnt/beta-
123 ulture self-assembled into microvessels, and platelet-derived growth factor had chemotactic effect on
124 on into brains of mice engineered to express platelet-derived growth factor in the central nervous sy
126 razin-2(1H)-ones toward potent and effective platelet-derived growth factor receptor (PDGF-R) beta-in
127 ng fibroblast growth factor receptor (FGFR), platelet-derived growth factor receptor (PDGFR) and inte
129 st growth factor receptor (FGFR) family, the platelet-derived growth factor receptor (PDGFR) family,
131 YR mice had significantly reduced amounts of platelet-derived growth factor receptor (PDGFR), which i
132 platelet-derived growth factor BB (PDGF-BB)/platelet-derived growth factor receptor (PDGFR)-beta sig
133 isib also inhibited ALL proliferation in ABL/platelet-derived growth factor receptor (PDGFR)-mutant m
134 l stromal tumor (GIST) cells overexpress the platelet-derived growth factor receptor (PDGFR)A, althou
135 Anterograde transport mutants display low platelet-derived growth factor receptor (PDGFR)alpha lev
136 Nkx2.2 can directly bind to the promoter of platelet-derived growth factor receptor alpha (Pdgfra) a
137 GG), often in association with TP53 loss and platelet-derived growth factor receptor alpha (PDGFRA) a
139 -oncogene receptor tyrosine kinase (KIT) and platelet-derived growth factor receptor alpha (PDGFRA) m
140 errations in FLT3, tyrosine kinase 2 (TYK2), platelet-derived growth factor receptor alpha (PDGFRA),
144 many different signaling pathways, including platelet-derived growth factor receptor alpha (PDGFRalph
147 ellular origin of new myelin by fate mapping platelet-derived growth factor receptor alpha (PDGFRalph
148 a poor prognosis and exhibit an increase in platelet-derived growth factor receptor alpha (PDGFRalph
150 that TAg expression reduces the abundance of platelet-derived growth factor receptor alpha (PDGFRalph
151 ssed in primitive stromal cells that express platelet-derived growth factor receptor alpha and Sca-1
152 SMCs), interstitial cells of Cajal (ICC) and platelet-derived growth factor receptor alpha positive (
153 more, oncogenic RAB35 is sufficient to drive platelet-derived growth factor receptor alpha to LAMP2-p
154 ating with an increase in Il-6 expression in platelet-derived growth factor receptor alpha(+) mesench
155 differentiated alpha-smooth muscle actin(+)/platelet-derived growth factor receptor alpha(+)/CD44(+)
156 racterized by activating mutations of KIT or platelet-derived growth factor receptor alpha(PDGFRA), w
157 roblast growth factor receptors 1 through 4, platelet-derived growth factor receptor alpha, RET, and
158 atrix by increasing nonmuscle myosin II- and platelet-derived growth factor receptor alpha-mediated c
159 ntramuscular interstitial cells of Cajal and platelet-derived growth factor receptor alpha-positive c
162 press the mesenchymal stem cell (MSC) marker platelet-derived growth factor receptor alpha; hence, we
163 N, resulting in increased phosphorylation of platelet-derived growth factor receptor and activation o
165 factor receptor, heat shock protein 90, and platelet-derived growth factor receptor as well as mutua
166 ling and functional screening identified the platelet-derived growth factor receptor b (PDGFRb) as bo
167 ranscriptional response to Mucorales reveals platelet-derived growth factor receptor B (PDGFRB) signa
168 n profiling, which revealed up-regulation of platelet-derived growth factor receptor beta (Pdgfrb) an
169 protein Sestrin 2 (Sesn2) as a suppressor of platelet-derived growth factor receptor beta (Pdgfrbeta)
170 MEFs show slower kinetics of ligand-induced platelet-derived growth factor receptor beta (PDGFRbeta)
171 he overexpression and excessive signaling of platelet-derived growth factor receptor beta (PDGFRbeta)
175 Gint4.T aptamer specifically recognizes platelet-derived growth factor receptor beta and can cro
176 in 2 (IGFBP-2), nerve growth factor (b-NGF), platelet-derived growth factor receptor beta polypeptide
177 erved in a laser-induced model of CNV that a platelet-derived growth factor receptor beta positive (P
179 gnificantly more NIK(+) ECs and perivascular platelet-derived growth factor receptor beta(+) preFDCs,
180 g., expression of alpha smooth muscle actin, platelet-derived growth factor receptor beta, desmin, vi
182 structure provides a first glimpse into how platelet-derived growth factor receptor ECD, upon ligand
183 vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibitor PTK787
184 he vascular endothelial growth factor (VEGF)/platelet-derived growth factor receptor inhibitor suniti
185 ntibody or with small molecule inhibitors of platelet-derived growth factor receptor kinase or downst
186 tivation by a receptor activation loop (from platelet-derived growth factor receptor, a receptor tyro
187 lial cells and interstitial cells expressing platelet-derived growth factor receptor, alpha polypepti
188 ced RNA of epidermal growth factor receptor, platelet-derived growth factor receptor, and c-Met.
189 xpressing cells, nestin-expressing cells and platelet-derived growth factor receptor-alpha (PDGFR-alp
190 progenitors expressing a mesodermal marker, platelet-derived growth factor receptor-alpha (PDGFRA),
191 ell lines revealed co-activation of HER2 and platelet-derived growth factor receptor-alpha (PDGFRalph
192 opulation (SP) phenotype, PECAM-1 (CD31) and platelet-derived growth factor receptor-alpha (PDGFRalph
193 could be identified with antibodies against platelet-derived growth factor receptor-alpha (PDGFRalph
194 and flow sorted to isolate cells expressing platelet-derived growth factor receptor-alpha and exclud
195 ssion pattern, manifest in downregulation of platelet-derived growth factor receptor-alpha and recipr
196 to stabilize detrusor excitability involving platelet-derived growth factor receptor-alpha positive (
197 ild-type or constitutively activated PDGFRA (platelet-derived growth factor receptor-alpha) under con
198 tyrosine kinases (RTKs) such as PDGFRalpha (platelet-derived growth factor receptor-alpha), which sh
200 alpha signaling was conditionally blocked in platelet-derived growth factor receptor-alpha-positive a
201 y, 2) connective tissue progenitor cells, 3) platelet-derived growth factor receptor-alpha-positive c
203 nd dendritic spine formation through Rabex-5/platelet-derived growth factor receptor-beta (PDGFRbeta)
204 a significant decrease in the expression of platelet-derived growth factor receptor-beta, a tyrosine
207 structure of PDGFRbeta [a full-length human platelet-derived growth factor receptor], in complex wit
208 ne kinase activity of ABL1/BCR-ABL1 and KIT, platelet-derived growth factor receptors (PDGFRs), and t
210 of neuroprotective proteins and suggest that platelet-derived growth factor secretion in particular m
215 fically, we show how this transducer enables platelet-derived growth factor to trigger (in vitro) the
216 SMILR was also altered by interleukin-1alpha/platelet-derived growth factor treatment, and HAS2 expre
217 proteins (four antibodies and the chemokine platelet-derived growth factor) and two monovalent prote
218 d non-responders including stem cell factor, platelet-derived growth factor, and interleukin-15.
219 flammatory cytokines, invade Matrigel toward platelet-derived growth factor, and resist hypoxia-induc
220 th factors, such as epidermal growth factor, platelet-derived growth factor, and Wnt; and hormones, s
221 ice, including interleukin-1beta (IL-1beta), platelet-derived growth factor, angiopoietin 2, insulin-
223 factor, vascular endothelial growth factor, platelet-derived growth factor, interleukin (IL)-8, IL-1
224 the hepatic stellate cell (HSC) activators, platelet-derived growth factor, transforming growth fact
225 ine kinase ligands (epidermal growth factor, platelet-derived growth factor, vascular endothelial gro
226 o mediate the secretion of Pvf, a ligand for platelet-derived growth factor- and vascular endothelial
227 broblasts exhibit impaired responsiveness to platelet-derived growth factor-AA and sonic hedgehog, tw
228 e Boyden chamber and show that a gradient of platelet-derived growth factor-AB (PDGF-AB) expedites mi
229 sient treatment with AZA in combination with platelet-derived growth factor-AB converts primary somat
230 ), which when tethered to a surface acted as platelet-derived growth factor-BB (PDGF-BB) enhancers to
232 sforming growth factor-alpha (TGF-alpha) and platelet-derived growth factor-BB (PDGF-BB) were reduced
233 the receptor tyrosine kinase (RTK) agonist, platelet-derived growth factor-BB (PDGF-BB)-induced p21C
234 rom the culture of fat with ROS or PGZ on i) platelet-derived growth factor-BB (PDGF-BB)-stimulated p
235 atrix derivative (EMD) and recombinant human platelet-derived growth factor-BB (rhPDGF-BB) with beta-
236 e graft (CTG) (control) or recombinant human platelet-derived growth factor-BB + beta-tricalcium phos
237 tor-2, transforming growth factor-beta1, and platelet-derived growth factor-BB at 2 weeks compared wi
239 amel matrix derivative and recombinant human platelet-derived growth factor-BB plus beta-tricalcium p
240 s 200 ng of bone morphogenetic protein-2 and platelet-derived growth factor-BB that were eluted over
241 growth factor, interleukin 6, angiopoietin, platelet-derived growth factor-BB, placental growth fact
242 matory cytokines interferon gamma, IL-1, and platelet-derived growth factor-BB, which are not produce
244 despite constituting a small fraction of the platelet-derived growth factor-beta (PDGFRbeta)(+) cell
245 nsforming growth factor-beta [TGF-beta], and platelet-derived growth factor-beta [PDGF-beta]) and blo
247 ein oxidation within cells, and suggest that platelet-derived growth factor-dependent "redoxosomes,"
248 es insight into the vascular architecture of platelet-derived growth factor-driven glioblastoma.
249 genetic deletion mutant in a mouse model of platelet-derived growth factor-induced malignant oligode
255 factor], sCD40L [soluble CD40 ligand], PDGF [platelet-derived growth factor], RANTES [regulated on ac
259 atory diseases; however, the contribution of platelet-derived HMGB1 in thrombosis remains unexplored.
260 ecific ablation of HMGB1 and determined that platelet-derived HMGB1 is a critical mediator of thrombo
261 and hepatocytes suggested liver delivery of platelet-derived IDUA possibly via the clearance pathway
262 COMP) acts as a major endogenous plasma- and platelet-derived inhibitor of thrombin activity in vitro
263 In summary, a new neutrophil-activating platelet-derived lipid generated by COX-1 is presented t
264 In this review, we will discuss platelet and platelet-derived mediator interactions with the innate a
265 sponse to donor-specific antibodies and that platelet-derived mediators may be markers of evolving al
268 d electrochemical biosensor for detection of platelet-derived microparticles (PMPs), a major risk fac
269 rce microscopy (AFM) to quantify and qualify platelet-derived microparticles (PMPs), on the whole nan
276 plasma dramatically increases the number of platelet-derived MPs, contaminates the extracellular miR
277 tery occlusion after injury, indicating that platelet-derived MRP-14 directly regulates thrombosis.
278 of PAI-1 demonstrate a major contribution by platelet-derived PAI-1 in the treatment of lenti-miR-30c
280 length found in platelets (60-100 mer), and platelet-derived polyP significantly augment the plasmin
282 bute to thrombosis in animal models, whereas platelet-derived polyphosphate (polyP) may potentiate co
283 contain polyphosphate, and the secretion of platelet-derived polyphosphate has been associated with
287 further promoting the luminal deposition of platelet-derived regulated on activation normal T cell e
288 solid tumors in humans and mice and transfer platelet-derived RNA, including miRNAs, to tumor cells i
291 that FXIa neutralized both endothelium- and platelet-derived TFPI by cleaving the protein between th
294 he naive FVIII null hemophilia A (HA) mouse, platelet-derived VIII prevents both a primary and memory
295 henne et al present data showing the role of platelet-derived von Willebrand factor (VWF) in mediatin
296 created mice with either endothelial VWF or platelet-derived VWF and examined each phenotype for ble
300 r intriguing findings were that mice lacking platelet-derived VWF, but with adequate endothelial VWF
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