ライフサイエンスコーパス: platform

1 t apparatus, and a large cytoplasmic sorting platform.

2 es and spectra using the Illumina sequencing platform.

3 r the auspices of the PRACTALL collaboration platform.

4 e time and limit of detection (LOD) for each platform.

5 ision medicine in the clinic on the organoid platform.

6 ultiplexed aptamer-based affinity proteomics platform.

7 t optical parametric gains to date on a CMOS platform.

8 alescing RBPs through screens enabled by our platform.

9 no-objects on silicon-on-insulator photonics platform.

10 ize this finding in the design of the sensor platform.

11 rmation to prepare a new recyclable catalyst platform.

12 an be applied to a high-throughput automated platform.

13 a dorsal root ganglion microfluidics chamber platform.

14 ude in a compact, simple, and cost-effective platform.

15 pecific attachment of biomolecules to device platforms.

16 hese advances enhance the performance of POC platforms.

17 dencies across multiple and distinct genomic platforms.

18 rs characterized by multiple TCGA analytical platforms.

19 ancer type in non-TCGA datasets from diverse platforms.

20 ne has immense prospective for field-testing platforms.

21 g PSMA have been developed for SPECT and PET platforms.

22 raries compatible with multiplexed screening platforms.

23 construct sandwich type capillary detection platforms.

24 embrane microdomains that serve as signaling platforms.

25 nsitivity of C. elegans based drug discovery platforms.

26 ement and agreement across the three imaging platforms.

27 -like transport on a wide range of substrate platforms.

28 ercially available phenotypic identification platforms.

29 vide details for (i) establishing an inDrops platform (1 d); (ii) performing hydrogel bead synthesis

30 anide upconversion emission in a particulate platform allows the generation of binary temporal codes

31 A multi-instrument metabolomics-based platform along with targeted analyses was used to determ

32 s cytocompatible and tunable, rendering this platform amenable to studies of dynamic mechanics on cel

33 h sensitivity were 2.5 ng on the Ion Torrent platform and 10 ng on Illumina.

34 scale with a standard mammalian cell culture platform and a routine purification protocol.

35 isioned as a result of facile immobilization platform and immobilization strategy.

36 s with a fast-response pollution measurement platform and repeatedly sampled every street in a 30-km(

37 rate PD-L1 antibodies on 2 separate staining platforms and have their own scoring systems, which rais

38 Platelet Inhibition (CHAMPION PCI, CHAMPION PLATFORM, and CHAMPION PHOENIX) trials of patients under

39 , which is a scaffolding filament, signaling platform, and provider of passive tension and elasticity

40 gh assessments of new adjuvants, vaccination platforms, and antigens.

41 lth applications, game-based support, social platforms, and patient portals.

42 ta and how to build a completely new CellNet platform applicable to, for example, other species or ad

43 ive high power device paradigm on an Si CMOS platform are demonstrated.

44 Point-of-care (POC) diagnostic testing platforms are a growing sector of the healthcare industr

45 To explore these questions, experimental platforms are needed that can extensively and controllab

46 paper, we use a high-throughput microfluidic platform as a quantitative screen to assess peptide acti

47 hes that include the supported lipid bilayer platform as well as DNA tension sensor technologies.

48 d in randomly wrinkled matrice, are suitable platforms as novel adjuvants for cancer immunotherapy.

49 n individual laboratories and across imaging platforms, as well as multiplexed quantitative informati

50 le as a downloadable virtual machine or as a Platform-as-a-Service supported by a dedicated compute c

51 e design and fabrication of efficient sensor platforms based on nanostructures make the highly sensit

52 a need to develop methods that are robust to platform/batch effects and able to identify perturbed pa

53 s with antibody (antiHER2/APTMS-Fe3O4), as a platform bioconjugate (PB), and immobilized at a bare GC

54 ween RNA sequencing (RNA-seq) and microarray platforms, but have not studied their concordance at the

55 phosphorescence (RTP)-based oxygen detection platform by constructing core-shell nanoparticles with w

56 We tested this computational platform by detecting variations in mechanical output in

57 the sequencing throughput of the PacBio RSII platform by more than five-fold, while maintaining the a

58 ase-1, which is activated by various protein platforms called inflammasomes.

59 his issue, we developed a nanoparticle based platform, called nanoallergens that enable multivalent d

60 Our platform can accurately generate and control oxygen grad

61 In the fluorescence operation mode, the platform can attain the limit of detection 0.3ng/mL (1.5

62 This self-adherent transdermal MN platform can be applied to a variety of protein drugs re

63 This platform can be broadly applied to biological research,

64 or clinical diagnostic tool, we believe this platform can transform nutritional status assessment and

65 ting split samples with both cdPCR and ddPCR platforms can transfer the lambda traceability character

66 lization of a simple and versatile biosensor platform capable of high performance cardiac-bioassays f

67 rough integration with SynMap and its parent platform CoGe, assembled genomes are pre-loaded and avai

68 The developed platform combines the automatic generation of a drug gra

69 Here, we describe a hybrid platform combining common analysis pathways with the abi

70 rometry instrumentation, and data processing platforms continue to spur growth in the lipidomics fiel

71 cert with a mitochondria-adapted CRISPR/Cas9 platform, could prompt a revolution in mitochondrial gen

72 nocytogenes as a promising immunotherapeutic platform demands a thorough understanding of how cell de

73 ied to tissue sections of rat pituitary, the platform demonstrated improved spatial resolution, allow

74 Results A rolling-arms platform design with two to five experimental treatments

75 ntrolled trial using a multiarm, multistage, platform design.

76 l polymerase chain reaction (dPCR) end point platforms directly estimate the number of DNA target cop

77 charge-charge interaction, and 2) this depot platform enabled long-term, controlled release over 4wee

78 development and implementation of analytical platforms enabling detection and quantitation of adulter

79 Use of nanomaterials offers to biosensing platforms exceptional optical, electronic and magnetic p

80 ht/weight), worked equally well on different platforms, exhibited high specificity for crab over othe

81 The C-dot-hydrogel platform exhibits high sensitivity and detected ROS gene

82 he realization of novel single cell analysis platforms focused on circulating tumor cells (CTCs).

83 ord (SC) neurons grown using a compartmented platform followed by next-generation sequencing (NGS) te

84 nome sequencing was performed on an Illumina platform, followed by genome-wide chromosomal copy numbe

85 Electrochemical sensors are an attractive platform for analytical measurements due to their high s

86 alidated a rapid, reproducible, and low-cost platform for assessing drug responses in patient tumors

87 vironmental gradients while also providing a platform for assessments of covariation among root, leaf

88 This work not only identifies Daple as a platform for cross-talk between Akt and the noncanonical

89 he European Nucleotide Archive offers a rich platform for data sharing, publishing and archiving and

90 Cs are a safe and simply prepared all-in-one platform for delivery of drugs with different solubiliti

91 ock-in detection provides a high-performance platform for detecting small differences with standard f

92 is the first protocol that provides a common platform for directed differentiation of cardiomyocytes

93 dimensional (2D) materials offer a promising platform for exploring condensed matter phenomena and de

94 atments and provides an efficient production platform for expressing relaxin/insulin superfamily pept

95 Myristoylated ELPs provide a versatile platform for genetically pre-programming self-assembly i

96 N DBRs thus provide a promising and scalable platform for high performance GaN-based optoelectronic,

97 Here we describe a platform for identifying target-binding cystine-dense pe

98 posite played a dual role in this work, as a platform for imprinting of bacteria as well as a partici

99 aced short palindromic repeats (CRISPR)-Cas9 platform for in situ high-content functional analysis of

100 We present a platform for integrated analysis of functional and trans

101 We used the L1000 platform for large-scale profiling of 978 representative

102 tumors and provide a promising new delivery platform for localized gene therapy in the brain.

103 Cellulose paper is an ideal diagnostic platform for low-cost, easily disposable and lightweight

104 e, we present Seq-Well, a portable, low-cost platform for massively parallel single-cell RNA-seq.

105 We developed a platform for microfluidics-assisted cell screening (MACS

106 sm for disease-associated SNVs and provide a platform for modeling morphological changes in mental di

107 e of splicing in disease, which offers a new platform for molecular discovery and therapy.

108 -exosomal cargoes may constitute a biomarker platform for monitoring rejection.

109 ign, construction, and characterization of a platform for multiplexed analysis of disease-specific DN

110 s makes the avidin-biotin system a versatile platform for nanotechnology.

111 These data suggest a novel platform for nATC delivery using a slight modification o

112 Here we describe ShootingStar, a platform for perturbation analysis in vivo, which combin

113 PSCs provide an essential platform for RAS-induced phosphorylation and activation

114 sor design thus provides a promising sensing platform for real-time detection and optical determinati

115 tal-free photocatalysts presents a promising platform for renewable and sustainable energy.

116 Double quantum dots (DQDs) are a versatile platform for solid-state physics, quantum computation an

117 sh and mammals and establish an experimental platform for studying how evolutionarily distilled regul

118 esults establish CRISPR-Cas13a as a flexible platform for studying RNA in mammalian cells and therape

119 urce-poor countries of AFP surveillance as a platform for surveillance of vaccine-preventable disease

120 tensive use of Saccharomyces cerevisiae as a platform for synthetic biology, strain engineering remai

121 These results open a new platform for the additive manufacturing techniques, for

122 ysical properties and potency, and provide a platform for the cytosolic delivery of nucleic acids.

123 ochemical bio-sensor may provide a potential platform for the detection of QA in the real samples for

124 mation and bone loss, suggesting a promising platform for the development of a new host modulation th

125 This work provides a platform for the development of highly sensitive molecul

126 es show the potential of an alternative LAIV platform for the development of IBV vaccines.IMPORTANCE

127 ntly established a citrate-derived synthesis platform for the development of new fluorescence sensors

128 arly, this knowledge represents an important platform for the development of novel therapeutic option

129 lt in hPINK1 loss-of-function and provides a platform for the exploration of small molecule modulator

130 Here, we report a chemical proteomic platform for the global and quantitative analysis of lys

131 omic clusters makes Apt/AuAC/Au an excellent platform for the LPS detection.

132 ral model shows how Ragulator functions as a platform for the presentation of active Rags for mTORC1

133 hemistry described in this report provides a platform for the rapid synthesis of agelastatin derivati

134 lectronic devices and can provide a physical platform for the realization of smart memories and machi

135 ators such as Cr-doped (Bi,Sb)2Te3 provide a platform for the realization of versatile time-reversal

136 trol, possibly providing an appropriate MGDG platform for the xanthophyll cycle.

137 riopotent stem cells may serve as a suitable platform for the xeno-generation of human tissues and or

138 port the use of human CMT1A fibroblasts as a platform for therapy testing.

139 of exchange for this period, offering a new platform for understanding ancient exchange based on act

140 el of prion diseases that offers a promising platform for understanding prion proteinopathies and adv

141 ity for its use as a live-attenuated vaccine platform for ZIKV and other clinically relevant flavivir

142 rformed to demonstrate the potential of this platform for: i) transforming growth factor (TGF)-beta1-

143 ltiple risks, and build on existing delivery platforms for feasibility of scale-up.

144 the need for new broad and easily modifiable platforms for H2S donation, we report here the preparati

145 sors offer low-cost and disposable detection platforms for real-world applications.

146 d as one of the most promising drug delivery platforms for the management of ocular diseases affectin

147 We developed a panel of tunable expression platforms for the prominent genus Bacteroides in which g

148 Our platform, for the first time, demonstrates the detection

149 This platform has a significant potential in applications suc

150 The SID-FT-ICR platform has been tested with several protein complex sy

151 This online 2D-LC-HCD-MS/MS platform has high enrichment efficiency with 85% of iden

152 The advent of social media and microblogging platforms has radically changed the way we consume infor

153 Even though high-throughput phenotyping platforms have been developed for controlled environment

154 ulating Fermi-Hubbard physics on solid-state platforms have been made.

155 ever, relatively few specialized homogeneous platforms have garnered significant use in biological st

156 NA interference (RNAi)-based gene regulation platforms have shown promise as a novel class of therape

157 To demonstrate the clinical value of our platform, human subject studies were performed in the co

158 d all-atom discrete molecular dynamics (DMD) platform, iFoldNMR, for rapid and accurate structure mod

159 of the colorimetric aptamer-based detection platform in its identification and detection with naked

160 Significant improvements to the platform in yield and accuracy, coupled with higher thro

161 To compare the performance of 4 PD-L1 platforms, including 2 FDA-cleared assays, 1 test for in

162 l collision energies, we proved the method's platform independence.

163 roving lignocellulosic biomass for the sugar platform industry.

164 sts a need for a comprehensive computational platform integrating all these sequences with associated

165 t of a simple and cost-effective optofluidic platform, integrating liquid-core PDMS waveguides, that

166 incorporation of global molecular profiling platforms into the routine clinical classification of ad

167 This platform is also suitable for detection of S.

168 culator is compact, its silicon-on-insulator platform is compatible with both superconducting qubits

169 In this paper, an innovative diagnostic platform is presented which provides automated molecular

170 This platform is robust, scalable, and well-suited for a vari

171 The presented RAPID biosensor platform is significantly faster and less labor intensiv

172 tional genomics workflows to Cloud Computing platforms is associated with a new level of integration

173 d effect transistors into biochemical sensor platforms is the requirement of a gate electrode, which

174 Therefore, we hereby report a microfluidic platform lab-on-a-disc (LOAD) to provide a sample-to-ans

175 stent with data previously acquired on Q-TOF platforms, matching predictions from known protein inter

176 he first time that a portable, random-access platform may be implemented in practice using nanopore s

177 hybrid dielectric-loaded nanoridge plasmonic platform may serve as a fundamental building block for v

178 amples visualized using the ImageStream((R)) platform (Millipore Sigma, Darmstadt, Germany), and conf

179 Electrochemical reduction of biomass-derived platform molecules is an emerging route for the sustaina

180 veloped an integrative, stand-alone workflow platform, named CIPHER, for the systematic analysis of s

181 d the results from three transcriptome-based platforms (Nanostring Elements, Agena LungFusion panel a

182 e Optimal Management of Platelet Inhibition [PLATFORM]: NCT00385138; A Clinical Trial Comparing Cangr

183 d States, potential studies and surveillance platforms needed to fill these gaps, and prioritizing ef

184 gical superconductors on the device-friendly platform of monolayer TMDs.

185 lytic virus vectors, development of delivery platforms of genes for vaccines or therapy, as well as m

186 such as the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES)

187 ildhood obesity using an Illumina microarray platform on sorted monocytes of 35 obese children and 16

188 CMOS platforms operating at the telecommunications wavelength

189 o other available next-generation sequencing platforms, PacBio single-molecule, real-time (SMRT) sequ

190 Pathology Image Informatics Platform (PIIP) is an NCI/NIH sponsored project intended

191 This differentiation platform provides a basis for generating distinct cardio

192 electrochemical, aptamer-based (E-AB) sensor platform provides a modular approach to the continuous,

193 Overall, this platform provides a rapid detection (5min) of the DENV w

194 This platform provides a simple stage for systematic derivati

195 Our VLP-based platform provides a source for a ZIKV vaccine and diagno

196 The expanded aptamer-based proteomic platform provides a unique opportunity for biomarker and

197 This platform provides the means to generate therapeutic ADCs

198 ying analysis tool suite "pgltools": a cross platform, pypy compatible python package available both

199 However, at present, each existing platform relies on a defined exogenous transcription act

200 Many of these platforms rely on thiol groups to tether DNA to gold sur

201 or the AuNPs/BPDT/AuE and the AgNPs/BPDT/AuE platforms, respectively.

202 We also show that docking of the sorting platform results in significant conformational changes i

203 In vitro studies confirmed the platform's biocompatibility and biodegradability.

204 The NS platform samples from a select subpopulation of cells wi

205 This versatile biosensor platform simultaneously exploits the pH dependency of li

206 Across all five GBS analysis platforms, SNP calls showed unexpectedly low convergence

207 single, dual and multiple unit microfluidic platforms (Solo-MFP, Duet-MFP and Quintet-MPF, respectiv

208 A platform strategy will create a network effect that will

209 retrial biomarker confidence within the same platform structure and makes clinical trial design decis

210 However, existing platforms suffer from low potency, inability to generate

211 However, these platforms suffer from serious limitations, including sma

212 logies in order to develop a multifunctional platform suitable for on-chip thermal treatments and on-

213 The DOCK-AND-LOCK (DNL) method is a platform technology that combines recombinant engineerin

214 We use this Cas13a-based molecular detection platform, termed Specific High-Sensitivity Enzymatic Rep

215 lts were highly comparable between the LC-MS platforms tested.

216 rmation and species per product from the PGM platform than PCR-CS.

217 monstrate an ultra-sensitive microfabricated platform that achieves (129)Xe polarizations reaching 7%

218 Here we describe a measurement platform that allows for the combined monitoring of elec

219 We report a rapid "sample-to-answer" platform that can be used for the quantitative monitorin

220 Here we describe a discovery platform that can identify stimulus-responsive enhancers

221 developed a point-of-care mobile phone-based platform that can quickly characterize a patient's level

222 Here, we report a 3D microfluidic platform that could be potentially used for a real-time

223 ess this need, we have developed a screening platform that enables accurate quantification of fluores

224 We present GraphSpace, a web-based platform that fosters team science by allowing collabora

225 Since this is the only vaccine platform that has completed Phase III clinical studies,

226 ingly, there is a need for a robust research platform that incorporates all data and provides integra

227 veloped a data integration and visualization platform that provides evidence about the association of

228 develop a heterogeneous photonic integration platform that provides such capabilities in a scalable o

229 ndboggle is an open source brain morphometry platform that takes in preprocessed T1-weighted MRI data

230 G GM-0111, we created an injectable delivery platform that transitioned in <5min from a liquid at roo

231 moves toward designing nanoscale electronic platforms that allow in vivo determinations.

232 of more complex pluricellular physiological platforms that incorporate diverse cues from the myocard

233 ilies, which resemble mobile gene-remodeling platforms that supply promoters and first exons.

234 We call this cultivation platform the 'isolation chip', or 'ichip'.

235 Here, we introduce a new platform, the C. elegans Natural Diversity Resource (CeN

236 Implemented on a microplate reader platform, the FDL-based approach enabled sensitive and h

237 atures colder than the dilution refrigerator platform, the incoming electrical connections, and the h

238 develop microchip based pesticide detection platforms, there is no compact microfluidic device for t

239 for signal enhancement on paper-based carbon platforms through gold nanoparticles electrogenerated fr

240 al Neural Networks (ANN), form an attractive platform to build risk metrics because they can easily i

241 -organic framework (MOF) confers a versatile platform to contrive next-generation chemical sensors, o

242 Here, we describe a generalizable platform to create dual-FP biosensors with large dynamic

243 tical framework of metabolism can serve as a platform to decode cancer metabolic plasticity and desig

244 his concept by using a nanoelectromechanical platform to demonstrate active tuning.

245 nd Mott-Schottky analysis on the same sensor platform to demonstrate multi-configurable modes.

246 th USP4 and this ternary complex serves as a platform to deubiquitinate PRP31 and PRP3.

247 These models offer a platform to enable new preclinical research into mechani

248 ptibility assessment, we employ the dropFAST platform to evaluate the antibacterial effect of gentami

249 loped a CRISPR-Cas9-based 'gene drive array' platform to facilitate efficient genetic analysis in C.

250 ase, with the application of a chemogenomics platform to identify strategies to protect neuronal cell

251 drogel reported here provides a new material platform to introduce a cost-effective and efficient oin

252 , this study presents a validated lipidomics platform to map the fecal lipidome, which integrates uni

253 biomimetic microsystem provides an enabling platform to mechanistically study transfusion-associated

254 This study illustrates an effective platform to produce controlled release formulation of an

255 would therefore offer a versatile and robust platform to produce highly functional therapeutics.

256 e designed a high-throughput chemical screen platform to quantify PGC-1alpha acetylation in cells and

257 electro-optic modulator (EOM) is a promising platform to realize this conversion.

258 stainable Development Goals provide a global platform to reduce ACEs and their life-course effect on

259 nstrate the use of photoredox catalysis as a platform to selectivity wherein the discrepancy in oxida

260 based off surface matrix may present the new platform to sensitively measure biomarkers electrochemic

261 external mutagenesis and a unique nanoscale platform to study structurally related biological electr

262 ulticellular spheroids serve as an excellent platform to study tissue behavior and tumor growth in a

263 f-principle, we used the TRBO-sgRNA delivery platform to target GFP in Nicotiana benthamiana (16c) pl

264 lopment of photoredox catalysis as a generic platform to target other redox-active side chains for na

265 tudies in cavity optomechanics provide a new platform to uncover quintessential architectures of chao

266 (NPs) can be used as ligand-multimerization platforms to activate specific cellular receptors in viv

267 late the reviewed technologies from research platforms to clinical therapies will also be discussed.

268 tabilization of Env trimers as well as other platforms to generate trimers that now span multiple sub

269 research efforts to develop high-throughput platforms to mechanically characterize single cells.

270 es, based on the development of quantitative platforms to precisely follow and measure subcellular an

271 plasmonic nanobiosensor paves a fascinating platform towards early detection of cancer tumour and is

272 Other 'omics' platforms trade coverage for sensitivity, although the d

273 We demonstrate platform validation with patch-clamp recordings from a v

274 encing and assembling a human genome on this platform was achieved for the first time.

275 An untargeted LC-MS/MS platform was implemented for monitoring variations in CH

276 nmental stress to bacteria in a microfluidic platform, we can correctly assign antibiotic susceptibil

277 eraging the multiplex capability of the Cpf1 platform, we demonstrate both synergistic and combinator

278 Using this translational platform, we demonstrated that amyloid-beta pathology re

279 To facilitate the VLP platform, we generated a stable cell line expressing hig

280 ell lines and a custom CRISPR/Cas9 screening platform, we identify the H3K9 methyltransferase SETDB1

281 Using this platform, we studied gold junctions with prototypical mo

282 however, for a soluble, versatile, HBC-based platform, which can be tailored by incorporation of elec

283 An innovative 3D growth platform, which enabled the FTE organoid to self-organiz

284 To this end we developed a nanoparticle (NP) platform, which is specifically targeted to the tumor mi

285 ackage can run in different commercial cloud platforms, which enables the user to seize the best offe

286 ed on 2D-fluid composites and CMOS photonics platform, while also representing a useful technological

287 This platform will greatly benefit both researchers and clini

288 reasing the efficiency of TET in this hybrid platform will increase both the up- and down-conversion

289 Here, we present a research platform, WINCS Harmoni, which can measure in vivo neuro

290 ode can be compiled for execution on popular platforms (Windows, Mac and Linux).

291 We have extended the platform with a database for curated simulation experime

292 REPAIR presents a promising RNA-editing platform with broad applicability for research, therapeu

293 t the development of a flexible microfluidic platform with fully integrated sensing for on-body testi

294 tumor margins, we developed new viral-based platforms with 2 specific gene reporters.

295 us 5000, RTVue XR Avanti, and Triton DRI OCT platforms with default layer segmentations were used to

296 the capability to handle multiple sequencing platforms with different error properties; it minimizes

297 and creating more decentralized data sharing platforms with fewer restrictions to data access.

298 he advance of nucleic acid nanotechnology, a platform within which reactions can be exquisitely contr

299 this review we survey engineered human liver platforms within the needs of different phases of drug d

300 periment, we have developed a data streaming platform, XCMS Stream, which capitalizes on the acquisit