ライフサイエンスコーパス: platform

1 e and fish gelatin species in a single assay platform.

2 nd amperometric biosensing in a microfluidic platform.

3 ed by an ultra-high-performance LC-tandem MS platform.

4 OCT machine-learning augmented segmentation platform.

5 ectrometry (PSI-MS) on a single instrumental platform.

6 xford Nanopore Technologies (ONT) sequencing platform.

7 f diverse experiments onto a single hardware platform.

8 pture-based next-generation sequencing (NGS) platform.

9 a three-dimensional (3D) ECM-based microgel platform.

10 ming for practical application in biosensing platform.

11 loidies using a recently established culture platform.

12 t of 28%, 35%, 40%, and 45% Hct on the nrLFA platform.

13 o characterize the performance of the sensor platform.

14 example of innovation on a multidisciplinary platform.

15 lation was measured using the Illumina 450 K platform.

16 gh-throughput and user-friendly microfluidic platform.

17 on levels were measured using the Nanostring platform.

18 l systems, and drug design in metalloprotein platforms.

19 e unable to efficiently drain adjacent marsh platforms.

20 owards multifunctional and multimodal sensor platforms.

21 me cell line or tissue measured on different platforms.

22 for the development of sensitive biosensing platforms.

23 ccines while developing entirely new vaccine platforms.

24 ing advanced nanobiosensor-based theranostic platforms.

25 tly developed bioprinted and liver-on-a-chip platforms.

26 reference coverage breadth was >99% for both platforms.

27 t directly scalable to current manufacturing platforms.

28 accessed information mainly via social media platforms.

29 The AEMS platform achieved a speed of 2.2 s/sample using only 10

30 t excellent performance of the 2-input BLADE platform across the range of possible circuits.

31 In summary, the platform affords high-throughput analyses of antibodies,

32 -like particles (VLPs) are important vaccine platforms against pathogenic threats, including Covid-19

33 Our platform allows for control of the local losses inside t

34 Thus, this experimental platform allows the study of human tumor initiation, pro

35 This VSV-CoV-2-S platform allows virus neutralization assays to be perfor

36 oughputs and customized organ-on-a-chip-like platforms along with printed 3D-cell structures.

37 ur results support the exploration of device platforms already used in energy research to identify ne

38 The platform also allowed recovery of ~450-900 IgG sequences

39 Our platform also allows facile visualization of drug effect

40 ailed to be translated to human disease, our platform also incorporated the evaluation of compounds i

41 Furthermore, H1 provides a structural platform alternative to the native fold for RNase P to b

42 cells on an extracellular matrix (ECM)-based platform alters cell behavior, including migration, prol

43 ts of a Metabo-ring trial involving 16 CE-MS platforms among 13 different laboratories spanning two c

44 ll necessarily require fully digital imaging platforms, an overhaul of legacy information-technology

45 develop a high-throughput in vivo screening platform and discover several driver variants of PIK3CA.

46 observed high concordance rates between our platform and other genotyping platforms for the 69 succe

47 ay be accessed via our website, online tools platform and programmatic interfaces, with updates made

48 asmid information from the PacBio sequencing platform and shorter chromosome size from the hybrid Oxf

49 Here, we develop a split dCas12a platform and show that it allows for the construction of

50 ings offer practical guidance for optimizing platform and software selection when designing an scRNA-

51 Here we use multiple observational platforms and an eddy-resolving ocean model to identify

52 uding different functional monomers, sensing platforms and materials employed to achieve the best sen

53 in mixtures, we compared different scRNA-seq platforms and several preprocessing, normalization and b

54 split fluorescent reporter characterization platform, and establish a library of 15 mutually orthogo

55 ere reliably inferred from different genomic platforms, and these characteristics displayed marked di

56 Therefore, PCL coated CL fibrous gel platforms appear to be good candidates for controlled dr

57 sion of specific tumor epitopes, making this platform applicable to all solid tumors.

58 Results of the scalable platform are enabling for applications requiring broad b

59 iPSC-derived cells in vitro, and co-culture platforms are beginning to yield insights into the compl

60 Such platforms are potentially capable of performing 3D cell

61 Using the established platform as gateways, seven different diol-convertible a

62 noparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the

63 ion of labeled peptides acquired on Orbitrap platforms at a minimum of 60,000 resolving power (at 400

64 containment system addresses the scarcity of platforms available for yeast despite their prevalent us

65 as (TCGA), with both RNA-Seq and array-based platforms available.

66 We demonstrate the construction of a vaccine platform based on a unique three-plasmid system to effic

67 ere we describe a high-throughput analytical platform based on denaturing size-exclusion ultraperform

68 Here we demonstrate the use of a HT platform based on desorption electrospray ionization (DE

69 nd convenient ultrahigh-throughput screening platform based on flow cytometric droplet sorting (FCDS)

70 address this problem, we designed a sensing platform based on poly(ethylene terephthalate) substrate

71 These results showcase a solid-state platform based on single coherent rare-earth ions for th

72 To this end, several new platforms based on single-molecule protein-sequencing ap

73 This review describes platforms benefiting from these cytosensors to identify

74 traditionally supported by micro-electronic platforms, but recently, photonic techniques for neurona

75 ed by inflammatory caspases within signaling platforms called inflammasomes.

76 and versatile biomaterial functionalization platform can provide new opportunities for immunotherapi

77 oduced from prokaryotic and human expression platforms, can employ a variety of cargo attachment stra

78 ved antigens, cDC1 function as an autonomous platform capable of antigen processing and priming for b

79 nd actuation hardware into a single low-cost platform, Chi.Bio facilitates novel experimental methods

80 The platform combines Ares Genetics' proprietary database AR

81 The presented platform combines the natural catabolism of charged amin

82 ading to the construction of a multireporter platform combining the flavivirus sensor with reporter d

83 have increased rapidly since 2012, with some platform companies having already been sold or recapital

84 We present an experimental platform comprised of cell and organoid derivatives from

85 A Galaxy platform conducts computationally intensive analyses and

86 trument (Copan) and incubated on the WASPLab platform (Copan), and plates were imaged at 0 and 24 hou

87 This platform could be an excellent tool for studying heart d

88 This fully synthetic and modular therapeutic platform could be an important therapeutic approach with

89 This platform could support long-term culture of intestinal o

90 Our open-source platform, CPMG (Composite Peptide Macrocycle Generator),

91 ustified the more powerful analyses of multi-platform data.

92 ng to intervention characteristics (delivery platform, delivery timing, and health system objective)

93 The two platforms demonstrate comparable performances; however,

94 After discharge, the analytical platform derived a personalized baseline model of expect

95 This platform, designed to mimic the tight extracellular migr

96 The experimental and computational platforms developed here provide a framework for underst

97 Dubbed as 'MatchMixeR', we model platform differences by a linear mixed effects regressio

98 y developed a simple and robust microfluidic platform, DropMap, to measure simultaneously the kinetic

99 Given astronaut use of touchscreen platforms during training and space flight and given the

100 Google and 2 social media platforms (Facebook, YouTube) were used to identify onli

101 ore presents a manufacturable nanoelectronic platform feasible for high-speed and low-noise sensing o

102 , it has been implemented in the open-access platform Fiji.

103 de an overview of oligonucleotide-based drug platforms, focusing on key approaches - including chemic

104 The domain provides a binding platform for 21 amino acid CIF peptide ligands, which ar

105 rious contender to the well-established GaAs platform for a wide range of applications relying on coh

106 onstrate QDB method as the first immunoassay platform for absolute quantitation of protein biomarkers

107 we describe a novel, biomimetic, human bone platform for advanced testing of implants in vitro, and

108 Paper is emerging as a versatile platform for automated fluid handling with a broad range

109 e created benchtop model provides an initial platform for better characterizing corneal puncture inju

110 icles (GPMVs) are a widely used experimental platform for biochemical and biophysical analysis of iso

111 This finding provides a stable nano-platform for chemo-drug delivery as well as an efficient

112 NPs represent a biocompatible drug delivery platform for chemotherapy resistant tumor treatment.

113 capillary electrophoresis using the ZipChip platform for comparative characterization of the monoclo

114 e semiconductors and demonstrate a materials platform for complex and molecularly thin superlattices,

115 These cancer avatar models provide a platform for comprehensive longitudinal assessment of hu

116 ch as Gene, dbGaP, and BLAST; and provides a platform for customized analysis and visualization.

117 e report here m7GHub, a comprehensive online platform for deciphering the location, regulation and pa

118 These data present a platform for delineating the biological underpinnings of

119 sed feature of developmental potential and a platform for delineation of cellular hierarchies.

120 Development of a rapid and portable platform for detecting and monitoring waterborne pathoge

121 y on the Arrayed Imaging Reflectometry (AIR) platform for detection of antibodies to SARS-CoV-2, SARS

122 nd 94.3% accuracy of the smartphone-based PD platform for detection of V. cholerae.

123 ts for 2 weeks, attesting the ability of the platform for drug assays employing cyclic drug exposure

124 Here we describe a platform for efficient Cas12a gene editing in Drosophila

125 ovide insight into morphogen evolution and a platform for engineering tissues.

126 further implementation in a fully automated platform for ESI-MS-based high-throughput screening.

127 The new multicore ring fibers provide a new platform for experiments of quantum effects in low-loss

128 al vdWH arrays provides a versatile material platform for exploring exotic physics and promises a sca

129 itive, and specific paper-based microfluidic platform for fast multiplexed detections of important bi

130 A dual platform for forging sp(2)-sp(3) and sp(3)-sp(3) carbon

131 trophoblast stem cells (TSCs) as an in vitro platform for future assessment of primate trophoblast de

132 dy establishes a precise genetic engineering platform for genetic studies of hMSCs and development of

133 TIC), with genetic heterogeneity providing a platform for HGSC evolution.

134 we show the therapeutic utility of BAs in a platform for high-throughput drug screening (HTS).

135 ovalent organic frameworks offer a molecular platform for integrating organic units into periodically

136 nature of perfluorocarbons provides a unique platform for introducing dynamic nano- and microdroplets

137 of self-organization and provide a powerful platform for investigating post-implantation embryogenes

138 identify the TaFeTe(4) polytypes as an ideal platform for investigation of 2D transport anisotropy an

139 addition, bromotryptophan was exploited as a platform for late-stage diversification by Suzuki-Miyaur

140 DNA-based probes constitute a versatile platform for making biological measurements due to their

141 ablishing ChromA as a top performing general platform for mapping the chromatin landscape in differen

142 Here we describe a platform for measuring arrestin recruitment kinetics to

143 antibody-TTR fusions may provide a powerful platform for multimerizing antibody and Fab fragments to

144 l chelate (FERM) was developed to serve as a platform for multimodal imaging probe development.

145 ot-carrier generation reveals a new material platform for near-infrared optoelectronic devices.

146 egarding mechanostability and can serve as a platform for novel mutagenesis studies as well as a poin

147 chetype nodal-loop semimetal and establish a platform for obtaining a deeper understanding of the qua

148 hly fecund, optically clear and an excellent platform for preclinical drug discovery studies.

149 cerebrocortical ventricular zones provide a platform for progenitor cell proliferation and migration

150 Here, we developed the first biosensor platform for rapid detection of otolin-1 and prestin, bl

151 We therefore developed a platform for rapid phage display screening of deep recom

152 the foundation for using GMR SV sensors as a platform for real-time, quantitative detection of protea

153 3D-printed rGO-PLA showed to be an excellent platform for sensing and biosensing purposes.

154 ptimized Cas9-AAV6-based genome editing tool platform for site-specific mutagenesis and integration o

155 sults show new potential for this instrument platform for studies of large protein and protein comple

156 This work not only provides an ideal platform for studying plasmonic photochemistry in aqueou

157 trinsically porous nanocarbons to serve as a platform for studying the transition from analyte sorpti

158 Here we describe a platform for the detection of IgG anti-drug antibodies t

159 These observations provide a platform for the development of new, integrated structur

160 ighlight exercise as a valuable experimental platform for the discovery of much-needed novel therapeu

161 sional van der Waals materials provide a new platform for the discovery of novel physics and effects.

162 Here, we describe a simple platform for the expansion of functional mouse HSCs ex v

163 this common starting structure and provide a platform for the production and diversification of this

164 The results provide an enlarged platform for the quest of topological Dirac fermions in

165 this Zr-MOL system, giving rise to an ideal platform for the selective oxidation of anthracene.

166 The NanoStringTM nCounter(R) is a platform for the targeted quantification of expression d

167 AMPK activation, thus providing a molecular platform for the therapeutic control of EB response.

168 In summary, these studies describe a platform for the therapeutic induction of antigen-specif

169 ductors have emerged as a promising Majorana platform for topological quantum computation.

170 This study provides a platform for ultrasound imaging to examine muscle oscill

171 series of new ruthenium complexes provide a platform for understanding how strong trans effect ligan

172 They provide a platform for understanding the pathogenesis of macular d

173 The model provides a platform for virtual experiments to explore diversity-fu

174 endly, and biocompatible material innovation platforms for applications in sensing, actuation, and lo

175 ion of SK2 synaptic levels might provide new platforms for developing treatments for AS and various f

176 pt a specific conformation, represent unique platforms for efforts to harness principles of enzyme fu

177 d captioning, and enabling digital dictation platforms for health care.

178 effects and opportunities to exploit QDs as platforms for quantum information science.

179 formulations, which are utilized in delivery platforms for RNA therapeutics.

180 dots (CDs) and their derivatives are useful platforms for studying electron-donor/acceptor interacti

181 progression in NF1 and provided preclinical platforms for testing therapies at each tumor grade.

182 es between our platform and other genotyping platforms for the 69 successfully genotyped SNPs (>96%)

183 ation of new ZMOFs that can act as versatile platforms for the in situ encapsulation of proteins unde

184 n be immediately implemented on existing BLI platforms for urgent COVID-19 studies, such as serosurve

185 model bacteria, the development of cell-free platforms from non-model organisms and multiplexed strat

186 This novel platform has the potential to provide new insights into

187 n and limited access to transparent software platforms have also exacerbated the problem.

188 of short-read sequencing technologies, these platforms have proven their ability to resolve some of t

189 context, so-called internally catalysed DCC platforms have started to receive more interest in this

190 there remains a trade-off between short-read platforms, having limited ability to sequence homopolyme

191 The platform holds tremendous potential for scaling up curat

192 finium Human MethylationEPIC (Illumina Inc.) platform in 2,325 adults 45-74 years of age who particip

193 of C. bovis using the Oxford Nanopore MinION platform in a nearby field laboratory and used the data

194 one simpler spatial task, finding a visible platform in the Morris water maze.

195 The review offers a platform in which the chemistry and biomedical research

196 multiplex human pluripotent stem cell (hPSC) platform, in which 30 isogenic disease lines are pooled

197 The platform-integrated algorithms could be applied to large

198 Without such platforms, investments could be considered risky.

199 The designed platform is based on the use of an amine-functionalized

200 This technology platform is broadly applicable to various diseases with

201 ression control in S. pneumoniae A selection platform is described that allows for straightforward id

202 eporting complications according to the ECCG platform is feasible in the Netherlands and facilitates

203 rogrammes across Europe, the ELIXIR Training Platform, led by the ELIXIR EXCELERATE Quality and Impac

204 reased accessibility of microbial sequencing platforms, many recent studies have investigated the lin

205 ortening the development cycle of NAATs, our platform may find use in point-of-care diagnosis.

206 Here we employed an innovative computational platform, Mining of Synthetic Lethals (MiSL), to identif

207 barrier, we have created a dynamic web-based platform, NASQAR (Nucleic Acid SeQuence Analysis Resourc

208 ed us to develop a high-throughput screening platform of cancer drugs in a quest to repurpose them fo

209 In conclusion, this work presents a platform of UHPLC-HRMS and LA-REIMS, complementing each

210 The post-functionalizable hybrid-POM platforms offer an opportunity to covalently link multi-

211 lar recycling endosome membranes were a core platform on which the critical early events of autophago

212 Ultimately, this MS(n) platform paired with ion/ion chemistry permitted identif

213 ase mechanisms and for use as drug screening platform, particularly for reagents designed to increase

214 Using our informatics platform pHinder, we identified a triad of buried acidic

215 testing candidate mAbs and emerging delivery platforms prior to human trials.

216 oton nuclear magnetic resonance metabolomics platform provided 230 metabolite measures: 51 lipids, fa

217 This xenogeneic platform provided explanted human lungs a supportive, ph

218 1T-MoS(2) platforms provided a novel template for the formation of

219 approach facilitates application to imaging platforms ranging from fluorescence, luminescence, photo

220 Platform's channels subject cell constructs to physiolog

221 ation in ambulatory studies using a Sequenom platform (San Diego, CA).

222 n fecal samples sequenced using the Illumina platform should be size-selected to enable merging of pa

223 based on datasets integrated from different platforms showed that using MatchMixeR achieved the best

224 of advanced nanobiosensor-based theranostic platforms taking advantage of RBC-delivery modalities.

225 sisted cataract surgery (FLACS) using Victus platform (Technolas Bausch and Lomb (B&L), Munich, Germa

226 address this issue, we have developed a new platform-TeSS-which aggregates geographically distribute

227 findings should be kept in mind when making platform testing decisions.

228 Here, we introduce a novel platform that allows IC-FPOP to occur in a sterile incub

229 on in vitro requires the presence of a dsRNA platform that binds both NS1 RBD and DHX30N.

230 ntrollable loading properties, is a flexible platform that can be extended to a wide range of materia

231 s, it can serve as a promising safe adjuvant platform that can help to protect against pandemics and

232 gh-throughput unbiased automated phenotyping platform that collects >2000 behavioral features based o

233 nd highly interpretable single-cell analysis platform that couples dominant pattern discovery with a

234 the fabrication of a novel electroanalytical platform that does not need expertise-required tasks.

235 pRiPP, an integrated genomic and metabolomic platform that employs machine learning to automate the s

236 e, we present a high-throughput microfluidic platform that enables the quantitative, single-cell prec

237 ep brain recording and stimulation (Mo-DBRS) platform that enables wireless and programmable intracra

238 A fully automated integrated analytical platform that included continuous water sampling, sample

239 e' hybrid-POMs constitute a valuable modular platform that permits coupling of POM properties with di

240 Proteins have evolved as a variable platform that provides access to molecules with diverse

241 to et al report an intestinal organoid-based platform that re-creates genetic susceptibility to T-cel

242 discovery pipeline, we set out to develop a platform that would be capable of quantifying tissue-lev

243 to the realization of wearable bioanalytical platforms that are poised to autonomously provide freque

244 the time to create integrative benchmarking platforms that incentivize ambitious, unified models.

245 d to a plastic optical fibre (POF) plasmonic platform, the analyte-induced nanoMIP-deformations ampli

246 he engineering science associated with these platforms, the interdisciplinary nature of this field of

247 on the different types of plasmonic sensing platforms, the pervasive challenges, and outlook on the

248 dendrimers are a promising targeted delivery platform to achieve effective glioblastoma treatment by

249 adiazole (energy acceptor) provided an ideal platform to achieve very rapid (picosecond time scale) a

250 N model as a robust preclinical experimental platform to address current barriers to improved prevent

251 Here, we developed a one-stop microfluidic platform to assemble and culture human cerebral organoid

252 Genetic association provides a robust platform to build our understanding of the etiology of t

253 We established a novel bioelectrochemical platform to characterize the catalytic behavior of NDH-2

254 matter into semiconductors and offers a new platform to design novel quantum devices by marrying the

255 It provides an optical platform to develop new multimolecular and functional im

256 These models provide a platform to elucidate the structural basis of RAF activa

257 -metal dichalcogenides (TMDs) offer an ideal platform to experimentally realize Dirac fermions.

258 nsulators (TI) provide an important material platform to explore quantum phenomena such as quantized

259 cancer, our screening assay may be used as a platform to identify both antiherpesviral and anticancer

260 We develop a droplet microfluidic platform to increase the concentration of analytes in so

261 SC-CMs provide an auspicious, relevant human platform to investigate extracellular signals for cardia

262 he use of hiPSC-derived brain organoids as a platform to investigate SARS-CoV-2 infection susceptibil

263 response, we used a rapid antibody discovery platform to isolate hundreds of human monoclonal antibod

264 We illustrate how to extend the platform to model specific virus types (e.g., hepatitis

265 cyte-derived macrophages, in a gut-on-a-chip platform to model the human intestine and key aspects of

266 monstrates the feasibility of using the EVLP platform to study miR signature in human lungs in respon

267 protein-ligand interface with an interactive platform to visually explore and interpret these motifs

268 ic structure changes can be exploited in COF platforms to give rapid, reversible sensing in systems t

269 abling application-specific analog computing platforms to solve computationally hard problems.

270 d (protein topography and migration analysis platform) to attempt to identify substrates and proteoly

271 In this platform trial of therapeutic agents, we randomly assign

272 However, most commercial MS platforms typically involve a separation or cleanup prio

273 Most HTS platforms use fluorescence and luminescence technologies

274 ample, sample and cellular heterogeneity and platform used) were critical in determining the optimal

275 Our platform uses small reagent volumes and inexpensive equi

276 the performance of a personalized analytical platform using continuous data streams to predict rehosp

277 sed, commercially available measles IgG test platforms using a set of 223 well-characterized serum sa

278 f ~30 min, the resulting bacterial detection platform was demonstrated to be fast and highly sensitiv

279 This experimental platform was further exploited for studying with intravi

280 The platform was used in combination with a sample pretreatm

281 ified, low-cost commercial robotic pipetting platform was utilized for one-pot sample preparation.

282 Using an online platform, we asked 15 clinicians to assess the relative

283 Here, using the nanophotonic silicon-nitride platform, we demonstrate a spatial-multiplexed DOPO syst

284 To develop this platform, we established a pan-transcriptome reference f

285 By leveraging the conjugation platform, we successfully engineer INS-1E, a beta-cell l

286 ize from the hybrid Oxford Nanopore-Illumina platform were noted.

287 rt the development of a droplet microfluidic platform, which enables high-throughput reaction discove

288 ng-range structural variation, and long-read platforms, which tend to have lower accuracy and/or thro

289 We validate the platform with a brain dialysate fluid sample and demonst

290 ) extracts output directly from a commercial platform with an undisclosed algorithm.

291 Targeting this platform with anti-IL7R antibody eliminates Ph(+) ALL ce

292 , user-friendly, sensitive, and specific NAT platform with great potential in point-of-care diagnosti

293 We developed a hepatic organoid platform with human cells that can be used to model comp

294 d valence band provide an unusual electronic platform with localized states for electrons and more di

295 d surface-enhanced Raman spectroscopy (SERS) platform with the capability to reverse the analyte-surf

296 ingly, it has become important to identify a platform with which high selectivity can be achieved.

297 r vaccine testing, an easily accessible cell platform would be desirable as an alternative to the tim

298 A high-throughput platform would greatly facilitate coronavirus disease 20

299 In summary, our yeast-display-based platform yields high-quality MHC-II-binding peptide data

300 We briefly introduce three epigenome-editing platforms: zinc-finger proteins, transcriptional activat