ライフサイエンスコーパス: pleasure

1 nnabinoid/orexin signals can amplify sensory pleasure).

2 on is strongly influenced by expectations of pleasure.

3 continued use of drugs that no longer bring pleasure.

4 reason given for taking alcohol or drugs was pleasure.

5 y of thinking about the paradox of aesthetic pleasure.

6 osely tied to challenge and interest than to pleasure.

7 icle for transforming negative emotions into pleasure.

8 urable stimuli or the capacity to experience pleasure.

9 its positive feedback reinforcement through pleasure.

10 ression and regulation of emotion and evokes pleasure.

11 the expectation is reduced pain or increased pleasure.

12 The time course of pleasure, across stimuli, is well-fit by a model with on

13 nerally considered an independent measure of pleasure, activated brain regions involved in reward cir

14 sort into three social-functional subtypes: pleasure, affiliative, and dominance.

15 mesolimbic dopamine system, may not generate pleasure after all.

16 Pleasure amplitude increases linearly with the feeling o

17 well-fit by a model with one free parameter: pleasure amplitude.

18 Drugs causing pleasure and addiction are comparatively recent and like

19 these chemical senses cannot only reduce the pleasure and comfort from food, but represent risk facto

20 The Roman poet Horace said poetry gives pleasure and instructs.

21 g, which is the consumption of food just for pleasure and not homeostatic need, is a suitable paradig

22 ago, as young graduate students, we had the pleasure and privilege of being in Joan Steitz's laborat

23 The nucleus accumbens (the pleasure and reward 'hub' in the brain) influences wheel

24 a may contribute to subjective experience of pleasure and reward during intoxication.

25 accumbens, a brain region thought to mediate pleasure and reward that could also contribute to the an

26 that emphasize limbic-regulated responses to pleasure and reward.

27 to help postmenopausal women maximize sexual pleasure and satisfaction.

28 d from stimuli that otherwise produce strong pleasure and spares that of less-pleasant stimuli.

29 : (a) the traditional hedonic view that drug pleasure and subsequent unpleasant withdrawal symptoms a

30 t cause enhanced "liking" reactions to sweet pleasure and that stimulate food intake.

31 The pleasures and satisfactions of teaching, writing, and sa

32 or emotion (implicit 'liking' and conscious pleasure) and (3) motivation (implicit incentive salienc

33 ch, and includes items assessing motivation, pleasure, and emotion expression.

34 symptomatology (including pessimism, loss of pleasure, and loss of interest in previously enjoyed act

35 m measures, self-report scales of sociality, pleasure, and motivation, and coded facial expressions.

36 iding ecosystem services, natural beauty and pleasure, and sustaining human lives is a message that r

37 Loss of the capacity to experience pleasure (anhedonia) is a core clinical feature of schiz

38 Minimizing pain and maximizing pleasure are conflicting motivations when pain and rewar

39 id release even in the absence of subjective pleasure associated with feeding, suggesting that metabo

40 n sum, we confirm Kant's claim that only the pleasure associated with feeling beauty requires thought

41 icate that this dopaminergic system mediates pleasure associated with music; specifically, reward val

42 happiness and defines well-being in terms of pleasure attainment and pain avoidance; and the eudaimon

43 The experience of beauty is a pleasure, but common sense and philosophy suggest that f

44 e argue that the fluency theory of aesthetic pleasure can be amended to meet the requirements of the

45 ng beauty requires thought but that sensuous pleasure can be enjoyed without thought and cannot be be

46 thought and disprove his claim that sensuous pleasures cannot be beautiful.

47 state, personality traits, pain or physical pleasure, deception, and even social status.

48 om negative social interactions and decrease pleasure derived from positive interactions.

49 t and fiction is distinct from the immediate pleasure deriving from sensory features, because it requ

50 s for pleasure generators, including classic pleasure electrodes and the mesolimbic dopamine system,

51 eported more improvement over time in sexual pleasure (EST1 = .32 and EST2 = .62; P = .001), less dis

52 ia reflects a reduced capacity to experience pleasure, evidence is mixed as to whether anhedonia is c

53 What contributes to the pleasure evoked by flavors?

54 amplified reward-relevant reactivity toward pleasure-evoking stimuli also.

55 olimbic reward brain networks in response to pleasure-evoking stimuli.

56 is unclear if this temporal dissociation of pleasure experience is also relevant in other symptoms l

57 e distraction greatly reduces the beauty and pleasure experienced from stimuli that otherwise produce

58 Here, participants continuously rated the pleasure felt from a nominally beautiful or non-beautifu

59 atum in motivation to smoke, anticipation of pleasure from cigarettes and relief of withdrawal sympto

60 consumers were deprived of satisfaction and pleasure from foods, experienced difficulties finding sa

61 Some healthy people fail to derive pleasure from music despite otherwise preserved perceptu

62 ), and evidence for the causal generation of pleasure (gained largely from brain manipulation studies

63 me of the best known textbook candidates for pleasure generators, including classic pleasure electrod

64 Stress reduction, pleasure, improved cognition and other central nervous s

65 stimuli, correlating with decreased interest/pleasure in and performance of activities.

66 We propose that pleasure in music arises from interactions between corti

67 d its involvement in reward, motivation, and pleasure in other domains.

68 ntial deficit or a diminished "capacity" for pleasure in patients with schizophrenia.

69 Anhedonia, or diminished interest or pleasure in rewarding activities, characterizes depressi

70 ncy toward one another in that we often take pleasure in seeing others succeed.

71 review evidence for neural representation of pleasure in the brain (gained largely from neuroimaging

72 While I take pleasure in the former, the overall contribution of the

73 -denial of food as well as most comforts and pleasures in life.

74 refrontal cortex is critical for mediating a pleasure-induced down-regulation of avoidance responses

75 We also find that strong pleasure is always beautiful, whether produced reliably

76 sm is a psychiatric disorder in which sexual pleasure is derived from inflicting pain, suffering, or

77 Pleasure is mediated by well-developed mesocorticolimbic

78 ychology to explain experiences of aesthetic pleasure is problematic because it is founded on a mecha

79 uations, the capacity to seek and experience pleasure is reduced, food intake is diminished and sexua

80 It has been suggested that pleasure is related to salience (behavioral relevance),

81 nhedonia, or markedly diminished interest or pleasure, is a hallmark symptom of major depression, sch

82 edonia, the diminished ability to experience pleasure, is an important dimensional entity linked to d

83 Liking, or pleasure itself, is generated by a smaller set of hedoni

84 Pleasure 'liking' is especially generated by restricted

85 Pleasure/liking seems to be the phenomenological express

86 ng studies have shown that musically induced pleasure may arise from the interaction between auditory

87 Whereas easily comprehended art may elicit pleasure, meaningfulness is more closely tied to challen

88 These emerging insights into brain pleasure mechanisms may eventually facilitate better tre

89 more than merely the products of accumulated pleasure memories-even a repulsive learned cue for unple

90 ctions, including those processing affective/pleasure/motivational, nociception, and mating-specific

91 ales: expression (four items) and motivation/pleasure (nine items).

92 dently predicted depression (little interest/pleasure: odds ratio [OR]=6.65, P<0.001; depression: OR=

93 Although the pleasure of eating is modulated by satiety and food depr

94 efrontal cortex system for signaling pain or pleasure of future prospects.

95 lsive, amygdala system for signaling pain or pleasure of immediate prospects, and a reflective, prefr

96 was helping young scientists experience the pleasure of performing creative research.

97 growing global consumer base appreciates the pleasures of coffee and chocolate and health warnings ar

98 Causation of core pleasure or 'liking' reactions is much more subcorticall

99 neuroscience aims to understand how affect (pleasure or displeasure) is created by brains.

100 nt on the reader's needs, in the moment, for pleasure or distraction.

101 ral substrate of the inability to experience pleasure or engage in rewarding activities, 3) provides

102 tendency to link dopamine transmission with pleasure or hedonia, as opposed to other aspects of moti

103 Anhedonia, the loss of pleasure or interest in previously rewarding stimuli, is

104 elates-depressed mood and anhedonia (loss of pleasure or interest).

105 , meaningfulness does not necessarily entail pleasure or positive emotions.

106 processing but of an inability to experience pleasure or positive motivation.

107 ed alertness and arousal, whereas effects on pleasure or relaxation were less consistent.

108 In affective disorders, anhedonia (lack of pleasure) or dysphoria (negative affect) can result from

109 scores for frequency of sexual activity and pleasure-orgasm in the Brief index of Sexual Functioning

110 ects the theater, which has given me so much pleasure over the years: "There is a time for departure

111 productive concerns (P < .0001), less sexual pleasure (P = .003), and lower scores on the total Sexua

112 that each additional 10 hours of reading for pleasure per week at the end of a progression interval w

113 te model, the number of hours of reading for pleasure per week was not significantly associated with

114 om exposures occurring during both work- and pleasure-related activities.

115 tions were: amusement, anger, disgust, fear, pleasure, relief, and sadness.

116 g population diets ought to consider sensory pleasure response to foods, in addition to a wide range

117 ryptamine (5-HT)] modulates mood control and pleasure response, whereas in the dSt, 5-HT regulates mo

118 (VTA) is thought to contribute generally to pleasure, reward, and drug reinforcement and has been im

119 dicating aberrant functional connectivity of pleasure/reward and fear circuits.

120 es how the clinical and neural signatures of pleasure, salience, allostasis and withdrawal relate, bo

121 t electrophysiological relationships between pleasure, salience, allostasis and withdrawal.

122 d to orient toward hedonic activities (e.g., pleasure seeking), potentially placing them at risk for

123 st that feeling beauty differs from sensuous pleasures such as eating or sex.

124 ilar circuitry is activated by quite diverse pleasures, suggesting a common neural currency shared by

125 ynecologic symptoms and diminution in sexual pleasure, survivors tended to have stronger, more positi

126 t poetry and art, in general, are less about pleasure than about exploration of emotions.

127 nia reflects a set of beliefs related to low pleasure that surface when patients are asked to report

128 y combining participants' estimations of the pleasure they will derive from future events, with brain

129 prefrontal cortex while subjects imagine the pleasure they would derive from items belonging to two d

130 bsequently enhances estimates of the hedonic pleasure to be derived from these same events.

131 enced in numerous ways, ranging from sensory pleasure to elaborated ways of finding meaning.

132 ch interaction is critical for music-induced pleasure to emerge, then those individuals who do not ex

133 I have had the opportunity and pleasure to interact with the ASCI not only as an organi

134 It has been a pleasure to watch that work take on a life of its own as

135 le anticipatory sensitivity and consummatory pleasure towards monetary incentives as the controls; bu

136 , hopelessness, loss of interest, or lack of pleasure) was present in 16.5% of subjects (95% CI, 16.0

137 d hours per week spent studying, reading for pleasure, watching television, playing video games or wo

138 DD (FH+) and anhedonia (reduced capacity for pleasure) were associated with altered white matter micr

139 opher Nagarjuna more aptly stated, "There is pleasure when an itch is scratched.

140 ed that active stroking elicits more sensory pleasure when touching others' skin than when touching o