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1 lls can be experimentally provoked to become pluripotent.
4 scle that is potentially applicable to other pluripotent cell lines and to generating other forms of
5 cells (EGCs) represent two classic types of pluripotent cell lines, yet their molecular equivalence
10 hether endothelial cells differentiated from pluripotent cells could serve as surrogates to test emer
11 iew recent insights into the nature of human pluripotent cells in vivo, obtained by the deep sequenci
18 molecular network that defines and restricts pluripotent developmental potential in cultured ESCs and
21 ons may therefore arise in germ cells and in pluripotent embryonic cells, prior to germline specifica
29 in resistance by inducing the expressions of pluripotent molecules Sox2 and Nanog and anti-apoptotic
31 eases L1-ORF1p levels and L1 mobilization in pluripotent mouse embryonic stem cells, implying that Te
33 uttle with messenger RNA to the cytoplasm in pluripotent P19 cells, but not in differentiated cells.
37 ough distinct anti-silencing activity in the pluripotent state and during PSC-differentiation for sev
38 the epigenetic memory of a somatic cell to a pluripotent state during cellular reprogramming requires
39 ly shown that E-cadherin regulates the naive pluripotent state of mouse embryonic stem cells (mESCs)
45 terion for the characterization of different pluripotent states, and show the relevance of transition
46 tly, epiblast cells transit through distinct pluripotent states, before lineage commitment at gastrul
47 CRISPR/Cas9 genome editing in human induced pluripotent stem (iPS) cell-derived neural progenitor ce
48 Further translational studies using induced pluripotent stem (iPS) cell-derived neuronal cells are n
54 o establish a patient-specific human induced pluripotent stem cell (hiPSC) model of CPVT2 and to use
57 ificantly improves the efficiency of induced pluripotent stem cell (iPSC) generation by the Yamanaka
58 type and mutant RTT patient-specific induced pluripotent stem cell (iPSC) line carrying the V247fs mu
59 is study, we derived a collection of induced pluripotent stem cell (iPSC) lines capturing a range of
61 ne expression profiling of 215 human induced pluripotent stem cell (iPSC) lines from different donors
65 ten the action potential duration in induced pluripotent stem cell (iPSC)-derived cardiomyocytes from
66 d the therapeutic potential of human induced pluripotent stem cell (iPSC)-derived cells at two differ
67 related genetic mutations in patient induced pluripotent stem cell (iPSC)-derived DAergic neurons and
70 he innate immune properties of human induced-pluripotent stem cell (iPSC)-derived RPE cells, particul
73 several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived dopamine neurons.
74 LA) class I genes can cause the rejection of pluripotent stem cell (PSC)-derived products in allogene
75 velopmental genes during the G1 phase of the pluripotent stem cell cycle contributes to cell fate dec
77 les and genetic screens, or applied to human pluripotent stem cell differentiation for beta-like cell
78 unique molecular mechanisms underlying human pluripotent stem cell differentiation into late primordi
79 ed from multiple human embryonic and induced pluripotent stem cell lines and have potential applicati
80 ain cell fates, our fragile X syndrome human pluripotent stem cell lines exhibited reproducible aberr
81 ing large-scale collections of human induced pluripotent stem cell lines provide valuable insight int
83 Here we show, using murine and human induced pluripotent stem cell models, that RPGR interacts with a
85 ociation Studies Consortium has used induced pluripotent stem cell technology to study the effects of
88 otent stem cells to generate a human-induced pluripotent stem cell-derived cardiac muscle patch (hCMP
89 ell device for functional screening in human pluripotent stem cell-derived cardiac organoids (hCOs).
90 onization within maturing, unlabeled induced pluripotent stem cell-derived cardiomyocyte cultures.
92 nd decreased beat amplitude in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
94 l studies of drug effects with human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
95 s to generate EHM from embryonic and induced pluripotent stem cell-derived cardiomyocytes and fibrobl
96 ed that commercially available human induced pluripotent stem cell-derived cardiomyocytes are a power
97 o supports the use of isogenic human induced pluripotent stem cell-derived cardiomyocytes as a physio
99 electrophysiological maturation of the human pluripotent stem cell-derived cardiomyocytes in our syst
100 d in rodent cardiomyocytes and human induced pluripotent stem cell-derived cardiomyocytes in vitro an
101 sion produced a functional rescue in induced pluripotent stem cell-derived cardiomyocytes with D130G-
102 eded with approximately 50 000 human-induced pluripotent stem cell-derived cardiomyocytes, smooth mus
105 tro models, such as isolated adult and human pluripotent stem cell-derived cardiomyocytes; (2) 2-dime
106 yocyte monolayers or small clusters of human pluripotent stem cell-derived cardiomyocytes; (3) 3-dime
108 rat ventricular myocytes, and human induced pluripotent stem cell-derived CMs, decreasing expression
110 ls, patient-derived fibroblasts, and induced pluripotent stem cell-derived dopaminergic neurons.
112 n the lung, our study indicates that induced pluripotent stem cell-derived endothelial cells are usef
114 xytoluene, in endocrine-active human-induced pluripotent stem cell-derived foregut epithelial cells a
120 logy of mice hippocampal neurons and induced pluripotent stem cell-derived neurons from a patient car
121 the underlying pathophysiology using induced pluripotent stem cell-derived neurons from AS patients a
122 kdown of Parkin or SLP-2, as well as induced pluripotent stem cell-derived neurons from Parkin mutati
123 agy, which is also apparent in human induced pluripotent stem cell-derived neurons, a disease-relevan
124 , but also exacerbated cell death in induced pluripotent stem cell-derived primary human neurons unde
125 stablished conditions by which human induced pluripotent stem cell-derived sensory neurons can be cul
126 expressed in either rodent or human induced pluripotent stem cell-derived sensory neurons in vitro p
127 Myelinating co-cultures using human induced pluripotent stem cell-derived sensory neurons thus provi
129 tipotent (mesenchymal and hematopoietic) and pluripotent stem cells (embryonic and induced) for regen
130 of cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs), 41 were accurately q
131 o generate cardiomyocytes from human induced pluripotent stem cells (hiPSCs) and human embryonic stem
134 dye transfer assay showed that human induced pluripotent stem cells (hiPSCs) contained functional gap
135 ac tissue (LF-ECT) composed of human induced pluripotent stem cells (hiPSCs) derived multiple lineage
136 We report the derivation of human-induced pluripotent stem cells (hiPSCs) from patients with diagn
143 an be successfully differentiated from human pluripotent stem cells (hPSCs) and hold the potential to
147 ar pluripotency and differentiation in human pluripotent stem cells (hPSCs) has yet to be systematica
148 testinal organoids differentiated from human pluripotent stem cells (hPSCs) have revolutionized the s
150 strate the capability to differentiate human pluripotent stem cells (hPSCs) into kidney structures.
151 ation of hematopoietic stem cells from human pluripotent stem cells (hPSCs) is a major goal for regen
153 ssion level, we genetically engineered human pluripotent stem cells (hPSCs) to express various N-term
156 In recent years, rapid emergence of induced pluripotent stem cells (iPSC) and iPSC-derived cardiomyo
157 ate oligodendrocytes (OL) from human induced pluripotent stem cells (iPSC) are currently lacking, but
160 report the differentiation of human induced pluripotent stem cells (iPSC) into microglia-like cells
161 complex (TSC) and LAM (TSC-LAM) into induced pluripotent stem cells (iPSC), followed by selection of
162 d body (EB) cells] from primed-state induced pluripotent stem cells (iPSCs) after a 72-hour transient
165 1) and used their tissue to generate induced pluripotent stem cells (iPSCs) and hepatocyte-like cells
170 ntotemporal dementia patient-derived induced pluripotent stem cells (iPSCs) carrying the Tau P301L mu
172 murine and human retinoblastomas and induced pluripotent stem cells (iPSCs) derived from murine rod p
178 opment, the present study used human induced pluripotent stem cells (iPSCs) from RTT and control indi
180 Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise fo
181 n leukocyte antigen (HLA)-homozygous-induced pluripotent stem cells (iPSCs) is considered a future cl
182 ramming of differentiated cells into induced pluripotent stem cells (iPSCs) is usually achieved by ex
184 w that astrocytes derived from human induced pluripotent stem cells (iPSCs) support the replication o
185 ed on a genetically diverse panel of induced pluripotent stem cells (iPSCs) that reproduces susceptib
186 variants through differentiation of induced pluripotent stem cells (iPSCs) to study cellular pathoph
187 Steering the differentiation of induced pluripotent stem cells (iPSCs) toward specific cell type
188 ganoids derived from control and MDS-induced pluripotent stem cells (iPSCs) using time-lapse imaging,
190 s derived from schizophrenia patient induced pluripotent stem cells (iPSCs) with a DISC1 mutation tha
191 of functional airway organoids from induced pluripotent stem cells (iPSCs) would provide valuable mo
193 knockdown neuroblastoma cell lines, induced pluripotent stem cells (iPSCs), and iPSC-derived cortica
194 We show that during reprogramming to induced pluripotent stem cells (iPSCs), fibroblasts from sterile
195 blished a liver organoid using human induced pluripotent stem cells (iPSCs), mesenchymal stem cells (
197 , stem cells as well as reprogrammed induced pluripotent stem cells (iPSCs), where the protein can al
203 using macrophages derived from human induced pluripotent stem cells (iPSdMs) to study macrophage-Chla
206 stem and progenitor cells (HSPCs) from human pluripotent stem cells (PSCs) has been a long-sought-aft
208 opmentally differentiated NKX2-1GFP reporter pluripotent stem cells (PSCs) in vitro to generate and i
211 neered by either directed differentiation of pluripotent stem cells (PSCs) or direct conversion, and
214 The in vitro-directed differentiation of pluripotent stem cells (PSCs) through stimulation of dev
215 tion has focussed on the conversion of human pluripotent stem cells (PSCs) to a more naive developmen
216 ineering approach with embryonic and induced pluripotent stem cells (PSCs) to generate human intestin
217 sis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with trophe
220 plications of hepatocytes derived from human pluripotent stem cells and challenges to using these cel
221 generated a genetic model of PKD using human pluripotent stem cells and derived kidney organoids.
222 Dividing cells called neoblasts contain pluripotent stem cells and drive planarian flatworm rege
223 aematopoietic stem and progenitor cells from pluripotent stem cells and holds promise for modelling h
224 viously unrecognized fate potential of human pluripotent stem cells and provides a platform for advan
227 ferentiation of four patient-derived induced pluripotent stem cells as a model for the onset of proge
228 cells can be successfully reprogrammed into pluripotent stem cells by the ectopic expression of defi
230 K293 cells and also overexpressed in induced pluripotent stem cells derived cardiomyocytes (iPSCs-CM)
231 nable its wide application in phenotyping of pluripotent stem cells for large scale stem cell culture
233 Using motor neurons derived from induced pluripotent stem cells from patients with ALS and FUS mu
234 neural progenitor cells derived from induced pluripotent stem cells from schizophrenia patients with
235 ds of access to and quality of human induced pluripotent stem cells has lagged behind their use.
238 s-enduring cells were identified as distinct pluripotent stem cells in mesenchymal cell populations i
239 progenitors (PPs) can be derived from human pluripotent stem cells in vitro but efficiency of differ
240 s and organoids have been derived from human pluripotent stem cells in vitro, but generating a human
241 nerate functional beta-like cells from human pluripotent stem cells in vitro, including from human in
243 is sufficient to differentiate human induced pluripotent stem cells into electrophysiologically activ
244 morphogen-directed differentiation of human pluripotent stem cells into haemogenic endothelium follo
245 factors can direct differentiation of human pluripotent stem cells into organoids - aggregates with
247 s from human embryonic stem cells or induced pluripotent stem cells is at present close to reality, a
248 et al. (2017) investigate mechanisms for how pluripotent stem cells maintain their identity during ce
251 ndromic autism pathophysiology using induced pluripotent stem cells modeling disease technology.
253 evertheless, to our knowledge, miRNAs in the pluripotent stem cells of one of the most commonly used
254 ty to propagate mature cells and tissue from pluripotent stem cells offers enormous promise for treat
257 d differentiation of patient-derived induced pluripotent stem cells showed a reduced expansion of lym
258 ion of arterial endothelial cells from human pluripotent stem cells that exhibit arterial-specific fu
259 erate three-dimensional spheroids from human pluripotent stem cells that resemble either the dorsal o
260 m with NPCs and neurons derived from induced pluripotent stem cells to create patient-specific cellul
261 t had been differentiated from human-induced pluripotent stem cells to generate a human-induced pluri
263 For example, attempts to differentiate human pluripotent stem cells to lung epithelium rely on passin
267 ted CSC-like cells by treating mouse induced pluripotent stem cells with conditioned medium from brea
268 at human cardiomyocytes derived from induced pluripotent stem cells with enhanced expression of isofo
269 th human cardiomyocytes derived from induced pluripotent stem cells with enhanced Kir2.1 expression a
270 ngs constitute a first step toward capturing pluripotent stem cells with extraembryonic developmental
271 to a selection of biological systems: human pluripotent stem cells with their cardiac derivatives, m
272 an extra human chromosome and human induced pluripotent stem cells with trisomy 21, as well as cance
273 nterferes with neural specification of human pluripotent stem cells, a process equating to the earlie
274 itates the generation of more robust induced pluripotent stem cells, characterized by enhanced plurip
275 of Nudt21 enhanced the generation of induced pluripotent stem cells, facilitated transdifferentiation
276 ming by transcription factors (i.e., induced pluripotent stem cells, iPSCs) or by somatic cell nuclea
277 2 hiPSC lines and 2 hESC lines at 4 stages: pluripotent stem cells, mesoderm, cardiac mesoderm, and
278 reprogrammed fibroblasts to generate induced pluripotent stem cells, neural progenitor cells (NPCs) a
279 human neural progenitor cells, human induced pluripotent stem cells, or in primary rat cortical neuro
280 nto three domains: the lineage commitment of pluripotent stem cells, the appropriation of primordial
281 expands the developmental potential of mouse pluripotent stem cells, yielding both embryonic and extr
299 we demonstrate that the epithelium of human pluripotent stem-cell-derived human intestinal organoids
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