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1 et production by megakaryocytes derived from pluripotent stem cells.
2 specific cell populations derived from human pluripotent stem cells.
3 mouse embryonic stem cells and human induced pluripotent stem cells.
4 al layers of global gene regulation in human pluripotent stem cells.
5 eprogramming somatic cells to become induced pluripotent stem cells.
6 ing sites in NPCs are largely preexisting in pluripotent stem cells.
7 ls of human disease to be generated-e.g., in pluripotent stem cells.
8 procedures that yield low numbers of induced pluripotent stem cells.
9 s of the miR-200 family, was detected in rat pluripotent stem cells.
10 generating chamber-specific cell types from pluripotent stem cells.
11 e in single embryonic stem cells and induced pluripotent stem cells.
12 ebral cortical spheroids (hCSs) derived from pluripotent stem cells.
13 of neurogenesis in fragile X syndrome human pluripotent stem cells.
14 ic fibroblasts are reprogrammed into induced pluripotent stem cells.
15 esenchymal transition, and the enrichment of pluripotent stem cells.
16 on of mouse embryonic stem cells and induced pluripotent stem cells.
17 us-specific DNA demethylation in somatic and pluripotent stem cells.
18 an neural progenitor cells and human induced pluripotent stem cells.
19 tion of embryonic-like structures from human pluripotent stem cells.
20 histone modifications, are a key property of pluripotent stem cells.
21 kouts in diploid or aneuploid cells, such as pluripotent stem cells, 3D organoids and cell lines, by
22 nterferes with neural specification of human pluripotent stem cells, a process equating to the earlie
23 plications of hepatocytes derived from human pluripotent stem cells and challenges to using these cel
24 generated a genetic model of PKD using human pluripotent stem cells and derived kidney organoids.
27 aematopoietic stem and progenitor cells from pluripotent stem cells and holds promise for modelling h
29 viously unrecognized fate potential of human pluripotent stem cells and provides a platform for advan
30 quisition of expanded cell fate potential in pluripotent stem cells, and it represses MERVL expressio
33 ferentiation of four patient-derived induced pluripotent stem cells as a model for the onset of proge
37 f tissue lineages can be differentiated from pluripotent stem cells by mimicking embryonic developmen
38 cells can be successfully reprogrammed into pluripotent stem cells by the ectopic expression of defi
39 ntotemporal dementia patient-derived induced pluripotent stem cell carrying the Tau P301L mutation an
40 itates the generation of more robust induced pluripotent stem cells, characterized by enhanced plurip
42 velopmental genes during the G1 phase of the pluripotent stem cell cycle contributes to cell fate dec
44 K293 cells and also overexpressed in induced pluripotent stem cells derived cardiomyocytes (iPSCs-CM)
45 otent stem cells to generate a human-induced pluripotent stem cell-derived cardiac muscle patch (hCMP
46 ell device for functional screening in human pluripotent stem cell-derived cardiac organoids (hCOs).
47 onization within maturing, unlabeled induced pluripotent stem cell-derived cardiomyocyte cultures.
50 l studies of drug effects with human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
51 nd decreased beat amplitude in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
52 s to generate EHM from embryonic and induced pluripotent stem cell-derived cardiomyocytes and fibrobl
53 ed that commercially available human induced pluripotent stem cell-derived cardiomyocytes are a power
54 o supports the use of isogenic human induced pluripotent stem cell-derived cardiomyocytes as a physio
56 electrophysiological maturation of the human pluripotent stem cell-derived cardiomyocytes in our syst
57 d in rodent cardiomyocytes and human induced pluripotent stem cell-derived cardiomyocytes in vitro an
59 sion produced a functional rescue in induced pluripotent stem cell-derived cardiomyocytes with D130G-
60 eded with approximately 50 000 human-induced pluripotent stem cell-derived cardiomyocytes, smooth mus
63 tro models, such as isolated adult and human pluripotent stem cell-derived cardiomyocytes; (2) 2-dime
64 yocyte monolayers or small clusters of human pluripotent stem cell-derived cardiomyocytes; (3) 3-dime
66 rat ventricular myocytes, and human induced pluripotent stem cell-derived CMs, decreasing expression
70 n the lung, our study indicates that induced pluripotent stem cell-derived endothelial cells are usef
72 n cells, including in vitro cultured induced pluripotent stem cell-derived forebrain neurons and in v
73 xytoluene, in endocrine-active human-induced pluripotent stem cell-derived foregut epithelial cells a
79 logy of mice hippocampal neurons and induced pluripotent stem cell-derived neurons from a patient car
80 the underlying pathophysiology using induced pluripotent stem cell-derived neurons from AS patients a
81 kdown of Parkin or SLP-2, as well as induced pluripotent stem cell-derived neurons from Parkin mutati
82 agy, which is also apparent in human induced pluripotent stem cell-derived neurons, a disease-relevan
83 , but also exacerbated cell death in induced pluripotent stem cell-derived primary human neurons unde
84 stablished conditions by which human induced pluripotent stem cell-derived sensory neurons can be cul
85 expressed in either rodent or human induced pluripotent stem cell-derived sensory neurons in vitro p
86 type III neuregulin-1 (TIIINRG1) in induced pluripotent stem cell-derived sensory neurons strongly e
87 Myelinating co-cultures using human induced pluripotent stem cell-derived sensory neurons thus provi
88 ubicin-induced cytotoxicity in human induced pluripotent stem cells-derived cardiomyocytes (iPS-CMs).
91 we demonstrate that the epithelium of human pluripotent stem-cell-derived human intestinal organoids
93 les and genetic screens, or applied to human pluripotent stem cell differentiation for beta-like cell
94 unique molecular mechanisms underlying human pluripotent stem cell differentiation into late primordi
95 tipotent (mesenchymal and hematopoietic) and pluripotent stem cells (embryonic and induced) for regen
96 of Nudt21 enhanced the generation of induced pluripotent stem cells, facilitated transdifferentiation
97 nable its wide application in phenotyping of pluripotent stem cells for large scale stem cell culture
99 Using motor neurons derived from induced pluripotent stem cells from patients with ALS and FUS mu
100 tes the self-renewing subpopulation of human pluripotent stem cells from powerful signals that drive
101 neural progenitor cells derived from induced pluripotent stem cells from schizophrenia patients with
102 ds of access to and quality of human induced pluripotent stem cells has lagged behind their use.
108 o establish a patient-specific human induced pluripotent stem cell (hiPSC) model of CPVT2 and to use
111 of cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs), 41 were accurately q
112 o generate cardiomyocytes from human induced pluripotent stem cells (hiPSCs) and human embryonic stem
115 dye transfer assay showed that human induced pluripotent stem cells (hiPSCs) contained functional gap
116 can be generated in vitro from human induced pluripotent stem cells (hiPSCs) derived from patients ca
117 ac tissue (LF-ECT) composed of human induced pluripotent stem cells (hiPSCs) derived multiple lineage
118 We report the derivation of human-induced pluripotent stem cells (hiPSCs) from patients with diagn
124 9-mediated genome editing coupled with human pluripotent stem cell (hPSC) directed differentiation.
125 e, we propose a novel approach using a human pluripotent stem cell (hPSC)-based 3D neocortical organo
127 an be successfully differentiated from human pluripotent stem cells (hPSCs) and hold the potential to
129 o culture complex retinal tissues from human pluripotent stem cells (hPSCs) could offer a means to st
132 ar pluripotency and differentiation in human pluripotent stem cells (hPSCs) has yet to be systematica
133 testinal organoids differentiated from human pluripotent stem cells (hPSCs) have revolutionized the s
134 a platform for the differentiation of human pluripotent stem cells (hPSCs) into functional cholangio
135 e progress has been made in converting human pluripotent stem cells (hPSCs) into functional neurons.
137 strate the capability to differentiate human pluripotent stem cells (hPSCs) into kidney structures.
138 ation of hematopoietic stem cells from human pluripotent stem cells (hPSCs) is a major goal for regen
141 ssion level, we genetically engineered human pluripotent stem cells (hPSCs) to express various N-term
143 es is recapitulated in differentiating human pluripotent stem cells (hPSCs), thereby providing a mode
145 s-enduring cells were identified as distinct pluripotent stem cells in mesenchymal cell populations i
146 progenitors (PPs) can be derived from human pluripotent stem cells in vitro but efficiency of differ
147 to recapitulate the development of HSCs from pluripotent stem cells in vitro In this Review, we discu
148 s and organoids have been derived from human pluripotent stem cells in vitro, but generating a human
149 nerate functional beta-like cells from human pluripotent stem cells in vitro, including from human in
152 is sufficient to differentiate human induced pluripotent stem cells into electrophysiologically activ
153 morphogen-directed differentiation of human pluripotent stem cells into haemogenic endothelium follo
154 factors can direct differentiation of human pluripotent stem cells into organoids - aggregates with
157 lia tips detected in fibroblasts and induced pluripotent stem cell (iPSC) 3D optic cups derived from
158 d isogenic human RTT patient-derived induced pluripotent stem cell (iPSC) and MeCP2 short hairpin RNA
160 ificantly improves the efficiency of induced pluripotent stem cell (iPSC) generation by the Yamanaka
161 type and mutant RTT patient-specific induced pluripotent stem cell (iPSC) line carrying the V247fs mu
162 is study, we derived a collection of induced pluripotent stem cell (iPSC) lines capturing a range of
164 ne expression profiling of 215 human induced pluripotent stem cell (iPSC) lines from different donors
169 rain specimens, we took advantage of induced pluripotent stem cell (iPSC) technology to model the dis
170 was significantly upregulated in SMA induced pluripotent stem cell (iPSC)-derived astrocytes and SMND
171 ten the action potential duration in induced pluripotent stem cell (iPSC)-derived cardiomyocytes from
172 d the therapeutic potential of human induced pluripotent stem cell (iPSC)-derived cells at two differ
173 related genetic mutations in patient induced pluripotent stem cell (iPSC)-derived DAergic neurons and
176 he innate immune properties of human induced-pluripotent stem cell (iPSC)-derived RPE cells, particul
177 engineered blood vessel (TEBV) using induced pluripotent stem cell (iPSC)-derived SMCs from an HGPS p
178 In recent years, rapid emergence of induced pluripotent stem cells (iPSC) and iPSC-derived cardiomyo
179 ate oligodendrocytes (OL) from human induced pluripotent stem cells (iPSC) are currently lacking, but
182 report the differentiation of human induced pluripotent stem cells (iPSC) into microglia-like cells
183 complex (TSC) and LAM (TSC-LAM) into induced pluripotent stem cells (iPSC), followed by selection of
184 d body (EB) cells] from primed-state induced pluripotent stem cells (iPSCs) after a 72-hour transient
187 1) and used their tissue to generate induced pluripotent stem cells (iPSCs) and hepatocyte-like cells
188 ing neurons derived from PWS patient induced pluripotent stem cells (iPSCs) and mouse models, the aut
193 ntotemporal dementia patient-derived induced pluripotent stem cells (iPSCs) carrying the Tau P301L mu
195 murine and human retinoblastomas and induced pluripotent stem cells (iPSCs) derived from murine rod p
201 opment, the present study used human induced pluripotent stem cells (iPSCs) from RTT and control indi
203 Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise fo
204 n leukocyte antigen (HLA)-homozygous-induced pluripotent stem cells (iPSCs) is considered a future cl
205 ramming of differentiated cells into induced pluripotent stem cells (iPSCs) is usually achieved by ex
207 w that astrocytes derived from human induced pluripotent stem cells (iPSCs) support the replication o
208 ed on a genetically diverse panel of induced pluripotent stem cells (iPSCs) that reproduces susceptib
209 variants through differentiation of induced pluripotent stem cells (iPSCs) to study cellular pathoph
210 Steering the differentiation of induced pluripotent stem cells (iPSCs) toward specific cell type
211 ganoids derived from control and MDS-induced pluripotent stem cells (iPSCs) using time-lapse imaging,
213 s derived from schizophrenia patient induced pluripotent stem cells (iPSCs) with a DISC1 mutation tha
214 of functional airway organoids from induced pluripotent stem cells (iPSCs) would provide valuable mo
216 knockdown neuroblastoma cell lines, induced pluripotent stem cells (iPSCs), and iPSC-derived cortica
217 We show that during reprogramming to induced pluripotent stem cells (iPSCs), fibroblasts from sterile
218 blished a liver organoid using human induced pluripotent stem cells (iPSCs), mesenchymal stem cells (
220 , stem cells as well as reprogrammed induced pluripotent stem cells (iPSCs), where the protein can al
227 ming by transcription factors (i.e., induced pluripotent stem cells, iPSCs) or by somatic cell nuclea
228 using macrophages derived from human induced pluripotent stem cells (iPSdMs) to study macrophage-Chla
229 s from human embryonic stem cells or induced pluripotent stem cells is at present close to reality, a
231 ed from multiple human embryonic and induced pluripotent stem cell lines and have potential applicati
232 ain cell fates, our fragile X syndrome human pluripotent stem cell lines exhibited reproducible aberr
233 rkinson's Disease, we have generated induced Pluripotent Stem Cell lines from early onset Parkinson's
234 ing large-scale collections of human induced pluripotent stem cell lines provide valuable insight int
237 et al. (2017) investigate mechanisms for how pluripotent stem cells maintain their identity during ce
239 2 hiPSC lines and 2 hESC lines at 4 stages: pluripotent stem cells, mesoderm, cardiac mesoderm, and
242 ndromic autism pathophysiology using induced pluripotent stem cells modeling disease technology.
243 Here we show, using murine and human induced pluripotent stem cell models, that RPGR interacts with a
244 reprogrammed fibroblasts to generate induced pluripotent stem cells, neural progenitor cells (NPCs) a
246 evertheless, to our knowledge, miRNAs in the pluripotent stem cells of one of the most commonly used
248 ty to propagate mature cells and tissue from pluripotent stem cells offers enormous promise for treat
249 human neural progenitor cells, human induced pluripotent stem cells, or in primary rat cortical neuro
250 etal muscle efficiently from porcine induced pluripotent stem cells (piPSC) in vitro thereby providin
255 several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived dopamine neurons.
256 LA) class I genes can cause the rejection of pluripotent stem cell (PSC)-derived products in allogene
257 problem that is particularly encountered in pluripotent stem cells (PSCs) and their differentiated p
260 stem and progenitor cells (HSPCs) from human pluripotent stem cells (PSCs) has been a long-sought-aft
262 isms, have been challenging to generate from pluripotent stem cells (PSCs) in part because there are
263 opmentally differentiated NKX2-1GFP reporter pluripotent stem cells (PSCs) in vitro to generate and i
266 neered by either directed differentiation of pluripotent stem cells (PSCs) or direct conversion, and
269 The in vitro-directed differentiation of pluripotent stem cells (PSCs) through stimulation of dev
270 tion has focussed on the conversion of human pluripotent stem cells (PSCs) to a more naive developmen
272 ineering approach with embryonic and induced pluripotent stem cells (PSCs) to generate human intestin
273 sis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with trophe
276 t to which in vitro differentiation of human pluripotent stem cells recapitulates bona fide human dev
279 d differentiation of patient-derived induced pluripotent stem cells showed a reduced expansion of lym
280 ociation Studies Consortium has used induced pluripotent stem cell technology to study the effects of
281 ion of arterial endothelial cells from human pluripotent stem cells that exhibit arterial-specific fu
282 erate three-dimensional spheroids from human pluripotent stem cells that resemble either the dorsal o
283 nto three domains: the lineage commitment of pluripotent stem cells, the appropriation of primordial
284 hat are derived from mouse and human induced pluripotent stem cells through a mechanism that involves
285 m with NPCs and neurons derived from induced pluripotent stem cells to create patient-specific cellul
286 t had been differentiated from human-induced pluripotent stem cells to generate a human-induced pluri
288 we report a method for differentiating human pluripotent stem cells to inner ear organoids that harbo
289 For example, attempts to differentiate human pluripotent stem cells to lung epithelium rely on passin
293 ted CSC-like cells by treating mouse induced pluripotent stem cells with conditioned medium from brea
294 at human cardiomyocytes derived from induced pluripotent stem cells with enhanced expression of isofo
295 th human cardiomyocytes derived from induced pluripotent stem cells with enhanced Kir2.1 expression a
296 ngs constitute a first step toward capturing pluripotent stem cells with extraembryonic developmental
297 titative single-cell analyses, we found that pluripotent stem cells with naturally short G1 phases lo
298 to a selection of biological systems: human pluripotent stem cells with their cardiac derivatives, m
299 an extra human chromosome and human induced pluripotent stem cells with trisomy 21, as well as cance
300 expands the developmental potential of mouse pluripotent stem cells, yielding both embryonic and extr
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