ライフサイエンスコーパス: pneumoniae

1 se OXA-48, in lysate samples from Klebsiella pneumoniae.

2 el for KPPR1, a highly virulent strain of K. pneumoniae.

3 ged with opsonized serotype 14 Streptococcus pneumoniae.

4 the virulence of the pathogen Streptococcus pneumoniae.

5 re important in the control of Streptococcus pneumoniae.

6 is approach for 2 serotypes of Streptococcus pneumoniae.

7 ence for coinfection with Streptococcus (S.) pneumoniae.

8 jor human respiratory pathogen Streptococcus pneumoniae.

9 correlated with the relative abundance of S. pneumoniae.

10 n of transcription factors in response to S. pneumoniae.

11 ential, and host-pathogen interactions of K. pneumoniae.

12 r most macrolide resistance in Streptococcus pneumoniae.

13 ted with relative abundance of Streptococcus pneumoniae.

14 cium, Acinetobacter baumannii and Klebsiella pneumoniae.

15 ation of specific serotypes of Streptococcus pneumoniae.

16 gens Streptococcus pneumoniae and Klebsiella pneumoniae.

17 the major respiratory pathogen Streptococcus pneumoniae.

18 s of public health strategies directed at S. pneumoniae.

19 synthesis and cell division of Streptococcus pneumoniae.

20 t 10 Staphylococcus aureus, 10 Streptococcus pneumoniae, 10 Haemophilus influenzae, and 5 Escherichia

21 -to-treat population (n=355) were Klebsiella pneumoniae (37%) and Pseudomonas aeruginosa (30%); 28% w

22 The most frequent organism was Klebsiella pneumoniae (375 [86%] of 437; 291 [85%] of 343 patients

23 ion by S. pyogenes, but not by Streptococcus pneumoniae, a bacterium that does not produce SAgs.

24 faecium, S taphylococcus aureus, K lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aerug

25 ally largely been associated with Klebsiella pneumoniae, a predominant plasmid (pKpQIL), and a specif

26 important for the immune response during M. pneumoniae acute infection.

27 died histidine triad protein D (PhtD), an S. pneumoniae adhesin vaccine candidate, for its ability to

28 odies against host proteins recognized by S. pneumoniae adhesins, we showed that S. pneumoniae uptake

29 Catabolism of galactose by Streptococcus pneumoniae alters the microbe's metabolism from homolact

30 ue identification identified correctly 46 S. pneumoniae and 4 S. pseudopneumoniae but misidentified 1

31 bmitted 2703 clinical isolates (2301 [85%] K pneumoniae and 402 (15%) E coli).

32 itis; Streptococcus viridians, Streptococcus pneumoniae and Coagulase negative Staphylococci in endop

33 eumoniae, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli in Conjunctivitis; Staph

34 rrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals.

35 th their cognate function against Klebsiella pneumoniae and Escherichia coli; vi) MAIT cell hyperacti

36 We test these predictions in S. pneumoniae and find that the duration of carriage of a s

37 stance, Staphylococcus aureus, Streptococcus pneumoniae and Haemophilus influenzae are the major caus

38 copies per LAMP zone for N. meningitidis, S. pneumoniae and Hib were achieved within 1h.

39 n by the major human pathogens Streptococcus pneumoniae and Klebsiella pneumoniae.

40 potential carbon and nitrogen sources for K. pneumoniae and of 99% in predicting nonessential genes i

41 Resistance Against Carbapenems in Klebsiella pneumoniae and Other Enterobacteriaceae) has contributed

42 ococcus faecium, platinum against Klebsiella pneumoniae and platinum and silver against Acinetobacter

43 gulase negative Staphylococci, Streptococcus pneumoniae and Pseudomonas aeruginosa are the leading is

44 unctional changes in the biofilms of both S. pneumoniae and S. aureus.

45 s provide a correct identification of all S. pneumoniae and S. pseudopneumoniae isolates.

46 ectra evaluation correctly identified all S. pneumoniae and S. pseudopneumoniae strains but misidenti

47 h susceptibility to subsequent Streptococcus pneumoniae and Staphylococcus aureus infection as well a

48 meningitidis), Streptococcus pneumoniae (S. pneumoniae), and Haemophilus influenzae type b (Hib) are

49 coli isolates by MIC and 30 S. aureus, 15 S. pneumoniae, and 15 S. pyogenes isolates by disk diffusio

50 MS-WF, mice were infected with Streptococcus pneumoniae, and bronchoalveolar lavage fluid (BALF) and

51 fter intratracheal instillation of PBS or S. pneumoniae, and differentially expressed (DE) mRNAs and

52 uberculosis, Salmonella enterica, Klebsiella pneumoniae, and Escherichia coli We compare patterns of

53 ipopolysaccharide, heat-killed Streptococcus pneumoniae, and Mycobacterium tuberculosis.

54 chia coli, Enterococcus faecalis, Klebsiella pneumoniae, and Pseudomonas aeruginosa We therefore conc

55 Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the most com

56 bacter cloacae, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa-reported here und

57 ng Streptococcus pyogenes, S. agalactiae, S. pneumoniae, and S. equi.

58 fluoroquinolone-resistant MRSA, VRE, and S. pneumoniae, and the possibility to offer patients an int

59 siella pneumoniae carbapenemase-producing K. pneumoniae; and present strategies used to halt the stri

60 Respiratory viruses and Streptococcus pneumoniae are known to be copathogens in childhood pneu

61 attesting to intracellular replication of S. pneumoniae as a key first step in pneumococcal pathogene

62 temic infection after lung challenge with S. pneumoniae As phospholipase A2 (PLA2) promotes the relea

63 us luteus, Bacillus subtilis, and Klebsiella pneumoniae at a minimal inhibitory concentration of 5.0m

64 calis ATCC 29212 (broth only), Streptococcus pneumoniae ATCC 49619 (disk and broth), and Haemophilus

65 for S. aureus ATCC 25923, 25 to 31 mm for S. pneumoniae ATCC 49619, and 16 to 20 mm for H. influenzae

66 alis ATCC 29212, 0.008 to 0.03 mug/ml for S. pneumoniae ATCC 49619, and 2 to 8 mug/ml for H. influenz

67 observed with regard to the prevention of S. pneumoniae bacteremia, and there was no difference in mo

68 ) is a structural tail protein of Klebsiella pneumoniae bacteriophage KP32, and is responsible for ad

69 teria were unable to significantly reduce K. pneumoniae burden in the blood or prevent dissemination

70 s, Haemophilus influenzae, and Streptococcus pneumoniae, but not other bacterial pathogens tested.

71 nd pH 5.5 (no growth of H. influenzae and S. pneumoniae by BMD).

72 Zinc intoxication is prevented in S. pneumoniae by expression of the zinc exporter CzcD, whos

73 bapenem-resistant human pathogen, Klebsiella pneumoniae, by B. bacteriovorus in human serum versus bu

74 , the main virulence factor of Streptococcus pneumoniae, by cryoEM.

75 e expression in macrophages infected with M. pneumoniae C57BL/6 mice deficient for NLRP3 expression w

76 We sought to determine whether S. pneumoniae can (1) translocate the heart, (2) induce car

77 because - in contrast to HRSV and HMPV - S. pneumoniae can become part of the nasopharyngeal flora,

78 During invasive pneumococcal disease, S. pneumoniae can gain access to the myocardium, kill cardi

79 In mice, Streptococcus pneumoniae can invade the myocardium, induce cardiomyocy

80 y) and the most frequent carbapenemase was K pneumoniae carbapenemase (329 [75%]; 253 [74%] vs 76 [81

81 CPOs carrying the Klebsiella pneumoniae carbapenemase (bla KPC ) gene have caused out

82 Imipenemase (IMP), Klebsiella pneumoniae carbapenemase (KPC), and Verona integron-enco

83 s the widespread dissemination of Klebsiella pneumoniae carbapenemase (KPC).

84 tics due to the production of the Klebsiella pneumoniae carbapenemase (KPC-2) class A beta-lactamase.

85 mmon transmissible CPE worldwide, Klebsiella pneumoniae carbapenemase-producing K. pneumoniae; and pr

86 ce plasmids, particularly variants of the K. pneumoniae carbapenemase.

87 ast to metallo-beta-lactamases or Klebsiella pneumoniae carbapenemases (KPC), no specific inhibitor i

88 st common resistance mechanisms were KPC (K. pneumoniae carbapenemases) beta-lactamases encoded by bl

89 Klebsiella pneumoniae carriage frequencies were estimated at 6% (95

90 The epidemic curve of incident K. pneumoniae cases showed a bimodal distribution of cases

91 Before 1945, Streptococcus pneumoniae caused more than 90% of cases of pneumonia in

92 Klebsiella pneumoniae causes a wide range of infections, from urina

93 Klebsiella pneumoniae causes severe lung and bloodstream infections

94 ulations and MZ B cells regulate systemic S. pneumoniae clearance through complementary mechanisms.

95 Nearly 25% of K. pneumoniae clinical isolates in a US network of LTACHs w

96 in genomic DNA extracted from E. coli or K. pneumoniae clinical isolates within a few minutes.

97 primarily involving KPC-producing Klebsiella pneumoniae clonal complex CC258.

98 These data confirm K. pneumoniae colonization is a significant risk factor for

99 I = 1.29-4.88; n = 921 participants), and S. pneumoniae community-acquired pneumonia (OR = 2.15; 95%

100 rial, resulting in eradication of Klebsiella pneumoniae compared with nonresponders.

101 In Streptococcus pneumoniae, competence develops transiently and synchron

102 cribe an outbreak of carbapenem-resistant K. pneumoniae containing the blaOXA-232 gene transmitted by

103 use glycoconjugates of type 3 Streptococcus pneumoniae CPS (Pn3P) to assess whether the carbohydrate

104 ns caused by carpabenem-resistant Klebsiella pneumoniae (CR-Kp) are especially problematic, with a 50

105 Resistance against Carbapenems in Klebsiella pneumoniae (CRACKLE) was constructed of patients with in

106 emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) represents a major public health threa

107 2-expressing carbapenem-resistant Klebsiella pneumoniae (CRKP) transmitted to 16 patients over the co

108 ns caused by carbapenem-resistant Klebsiella pneumoniae (CRKp).

109 A total of 3846 K. pneumoniae cultures were identified, with an overall car

110 from the midcells of dividing Streptococcus pneumoniae D39 background cells.

111 The intracerebral injection of S. pneumoniae D39 induced the recruitment of B and T cells

112 l distribution of multi-resistant Klebsiella pneumoniae demands faster antimicrobial susceptibility t

113 The respiratory pathogen Streptococcus pneumoniae deploys type IV pili to take up DNA during tr

114 We recently reported that an M. pneumoniae-derived ADP-ribosylating and vacuolating toxi

115 e we show that mice infected with Klebsiella pneumoniae develop lung injury with accumulation of card

116 date, for its ability to prevent invasive S. pneumoniae disease in adult and infant mice.

117 ndidate target in the development of anti-K. pneumoniae drugs.

118 sponse and influencing the progression of M. pneumoniae during acute infection.

119 0 days before intravitreal infection with S. pneumoniae E353.

120 ype I diabetic rabbit model of Streptococcus pneumoniae endophthalmitis.

121 S. pneumoniae established effective commensal colonization,

122 Streptococcus pneumoniae expresses capsular polysaccharides (CPSs) to

123 dition, in vivo infection with Streptococcus pneumoniae failed to induce PU.1 expression or upregulat

124 and also with potassium and thymidine for S. pneumoniae For all other variations, gepotidacin MIC and

125 f absorbance-value of 2.1, differentiated S. pneumoniae from all but one other mitis group streptococ

126 Reduction in yield of Streptococcus pneumoniae from NP culture was approximately 30% in case

127 TOF for the differentiation of Streptococcus pneumoniae from other mitis group streptococci, includin

128 described in this study can differentiate S. pneumoniae from other Streptococcus species.

129 treptococci, including differentiation of S. pneumoniae from Streptococcus pseudopneumoniae.

130 Analysis of the available K. pneumoniae genomes revealed that this pathogen's genome

131 ococcus pneumoniae Some components of the S. pneumoniae glycoconjugate vaccine Prevnar13 that contain

132 that Staphylococcus aureus and Streptococcus pneumoniae, Gram-positive bacterial pathogens of signifi

133 domonas aeruginosa, 16-32 mug/mL, Klebsiella pneumoniae > 32 mug/mL).

134 f IP children stimulated with heat-killed S. pneumoniae had significantly reduced percentages of CD4+

135 eba), six bacterial pathogens (Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitid

136 Klebsiella pneumoniae harboring blaKPC (KPC-Kpn) is endemic in many

137 l isolates of Eschericia coli and Klebsiella pneumoniae harboring NDM-1 were reduced to susceptible l

138 Klebsiella pneumoniae has a reputation for causing a wide range of

139 Streptococcus pneumoniae has demonstrated a remarkable ability to adap

140 pneumoniae has enhanced capacity to circumvent killing b

141 ainst Acinetobacter baumannii and Klebsiella pneumoniae; however, analogue 9 and 16 at 4 mug/mL decre

142 Hypervirulent Klebsiella pneumoniae (hvKP) is an emerging pathotype that is capab

143 ant sequence type 156 (ST156) serotype 9V S. pneumoniae in 3 respiratory patients that resulted in tw

144 of the opportunistic pathogen Streptococcus pneumoniae in an infant mouse model.

145 teraction between respiratory viruses and S. pneumoniae in CAAP pathogenesis.

146 cases and controls, with the exception of S. pneumoniae in exposed controls, which was detected 25% l

147 Reduced Th17 responses to S. pneumoniae in PBMCs of IP children can be rescued by add

148 teriovorus acting therapeutically against K. pneumoniae in serum, informing future research into the

149 e the evolution and spatial dispersion of K. pneumoniae in support of hospital infection control.

150 Studies on Mycoplasma pneumoniae in Thailand have focused on urban centers and

151 een, we identify a tropism for Streptococcus pneumoniae in this organ mediated by tissue-resident MZ

152 protection of mice against infection with S. pneumoniae in which iNKT cells have previously been foun

153 ropathogens Proteus mirabilis and Klebsiella pneumoniae, in addition to UPEC, in humans.

154 erbates nasal colonization and disease by S. pneumoniae, in part via the synergistic contributions of

155 ccharide transporter LptB2FG from Klebsiella pneumoniae, in which both LptF and LptG are composed of

156 uring pneumoseptic infection with Klebsiella pneumoniae, indicating its regulatory role in NET format

157 ly PP2C Ser/Thr phosphatase in Streptococcus pneumoniae, indicating that GpsB plays a key - but unkno

158 monstrated in a mouse model of Streptococcus pneumoniae-induced empyema.

159 logical inhibition of this enzyme blocked S. pneumoniae-induced PMN transepithelial migration in vitr

160 M. pneumoniae-infected macrophages deficient for inflammaso

161 ic effects of these factors on Streptococcus pneumoniae infection in mice.

162 m of PLA2 (cPLA2alpha) was activated upon S. pneumoniae infection of cultured lung epithelial cells a

163 e utilized in vitro and in vivo models of M. pneumoniae infection to characterize the role of the NLR

164 y, we used a model of low multiplicity of S. pneumoniae infection with HL-1 mouse cardiomyocytes to i

165 pinal fluid from children with Streptococcus pneumoniae infection, compared with children admitted to

166 During the acute phases of S. pneumoniae infection, these populations of splenic neutr

167 PLA2 in local and systemic disease during S. pneumoniae infection.

168 Carbapenem-resistant Klebsiella pneumoniae infections are increasingly prevalent in Nort

169 Streptococcus pneumoniae infections arising in hospitalized patients a

170 resurgence of severe community-associated K. pneumoniae infections has led to increased recognition o

171 of failure of Th17 immunity resulting in S. pneumoniae infections in children <2 years old.

172 s were identified, responsible for 12% of K. pneumoniae infections in ICU.

173 or infection in ICU, and indicate 50% of K. pneumoniae infections result from patients' own microbio

174 In sum, 49% of K. pneumoniae infections were caused by the patients' own u

175 ents with blaOXA-232 carbapenem-resistant K. pneumoniae infections were identified at a tertiary care

176 peutic strategy even for highly resistant K. pneumoniae infections, and underscore the effect humoral

177 There was no discrete seasonality to M. pneumoniae infections.

178 S. pneumoniae invades the myocardium and induces cardiac in

179 Indeed, S. pneumoniae invasion of HL-1 cells occurred through clath

180 The Streptococcus pneumoniae Invasive Disease network (SpIDnet) actively m

181 Streptococcus pneumoniae is a leading cause of invasive disease in inf

182 Mycoplasma pneumoniae is an atypical bacterial respiratory pathogen

183 pe-specific protection against Streptococcus pneumoniae is an important limitation of the current pol

184 Klebsiella pneumoniae is an opportunistic pathogen and leading caus

185 Pulmonary infection by Streptococcus pneumoniae is characterized by a robust alveolar infiltr

186 edge on the mechanisms whereby Streptococcus pneumoniae is cleared by the spleen.

187 ion of macrophage NF-kappaB by Streptococcus pneumoniae is highly diverse, with a preponderance of lo

188 Klebsiella pneumoniae is part of the healthy human microbiome, prov

189 Streptococcus pneumoniae is responsible for diseases causing major glo

190 Streptococcus pneumoniae is the main cause of bacterial meningitis, a

191 constituent of the pathobiont Streptococcus pneumoniae, is bound to peptidoglycan (wall teichoic aci

192 cell characteristics in an international K. pneumoniae isolate collection (n = 48), with a range of

193 of three plasmids in a reference Klebsiella pneumoniae isolate demonstrated approximately 99% accura

194 Klebsiella pneumoniae isolated from screening swabs and clinical di

195 coli, Pseudomonas aeruginosa, or Klebsiella pneumoniae) isolated from clinical cases.

196 hole genome sequences of 1,680 Streptococcus pneumoniae isolates from four independent populations us

197 ted NDM-1 carbapenemase producing Klebsiella pneumoniae isolates identified during an outbreak in a g

198 Carbapenemase-producing K pneumoniae isolates showed high resistance to last-line

199 ase (ESBL)-producing Escherichia coli and K. pneumoniae isolates using MinION allowed successful iden

200 ents with blaOxa-232 carbapenem-resistant K. pneumoniae isolates, including 9 with infections, 7 asym

201 ant clinical Escherichia coli and Klebsiella pneumoniae isolates, suggesting that they may be able to

202 371 isolates of Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, and Proteus mirabilis wi

203 Two types of Klebsiella pneumoniae (KP) strains are currently emerging: hypervir

204 f the Outer membrane protein A of Klebsiella pneumoniae (KpOmpA).

205 a coli PI-7, blaCTX-M-15-positive Klebsiella pneumoniae L7, and blaOXA-48-positive E. coli UPEC-RIY-4

206 with the common lung pathogens Streptococcus pneumoniae, Legionella pneumophila, or Mycobacterium tub

207 ia trachomatis, Escherichia coli, Klebsiella pneumoniae, Legionella pneumophila, Pseudomonas aerugino

208 Streptococcus pneumoniae, like many other naturally transformable spec

209 coli lipid A, whereas only LpxL2 mediated K. pneumoniae lipid A acylation.

210 show the increased prevalence of Klebsiella pneumoniae lipopolysaccharide O2 serotype strains in all

211 d for lethal systemic infection following S. pneumoniae lung challenge.

212 pecific than (18)F-FDG in differentiating K. pneumoniae lung infection from lung inflammation.

213 Thus, S. pneumoniae modulates mRNA and miR expression by lung neu

214 aphylococcus aureus (SaEf-Tu) and Mycoplasma pneumoniae (MpnEf-Tu), and the porcine pathogen Mycoplas

215 fluenzae, Neisseria meningitidis, Mycoplasma pneumoniae, Mycobacterium tuberculosis, and Bartonella),

216 pecies: Staphylococcus aureus, Streptococcus pneumoniae, Mycobacterium tuberculosis, Salmonella enter

217 ere most frequently identified in Klebsiella pneumoniae (n = 1,127), Escherichia coli (n = 149), and

218 Klebsiella pneumoniae (n = 180, 41.9%), Escherichia coli (n = 129,

219 An increase in Streptococcus pneumoniae nasopharynx (NP) colonization density during

220 with PCV13 led to a greater reduction of S. pneumoniae NP density (>2.5 log units) than PhtD vaccina

221 n, and influenza virus coinfection caused S. pneumoniae NP density to increase, resulting in bacterem

222 E coli isolates, 13 (<1%) of 348 Klebsiella pneumoniae, one (<1%) of 890 Enterobacter cloacae, and o

223 ated in vitro with heat-killed Streptococcus pneumoniae or CD3/CD28 antibodies and stained with a 38-

224 penem non-susceptible clinical isolates of K pneumoniae or E coli and ten susceptible same-species co

225 on of pathogenic bacteria, either Klebsiella pneumoniae or Salmonella enterica serovar Typhimurium, e

226 ly with Klebsiella pneumoniae, Streptococcus pneumoniae, or lipopolysaccharide.

227 -5.37; n = 2432 participants), Streptococcus pneumoniae otitis media (OR = 2.51; 95% CI = 1.29-4.88;

228 ome with regard to prevention of invasive S. pneumoniae pathogenesis with a protein vaccine similar t

229 To mimic natural S. pneumoniae pathogenesis, we commensally colonized the NP

230 multiresistant clinical strain of Klebsiella pneumoniae, PCM2713, and thus should be regarded as a du

231 Streptococcus pneumoniae (pneumococcus) is a major human pathogen.

232 Streptococcus pneumoniae (pneumococcus) is an oval-shaped, symmetrical

233 Streptococcus pneumoniae (pneumococcus) produces many capsule types th

234 eptidoglycan (PG) synthesis in Streptococcus pneumoniae (pneumococcus); yet, mechanisms of this switc

235 Early distinction between severe Mycoplasma pneumoniae pneumonia (MPP) and mild MPP is still difficu

236 (miRs) in lung neutrophils in mice during S. pneumoniae pneumonia and performed in depth in silico an

237 Lung neutrophils from mice with S. pneumoniae pneumonia contained 4127 DE mRNAs, 36% of whi

238 ased more than 2-fold in neutrophils from S. pneumoniae pneumonia.

239 Klebsiella pneumoniae poses a major challenge to healthcare worldwi

240 raminidase-expressing influenza virus and S. pneumoniae potentiates both colonization and infection b

241 isolates of Escherichia coli and Klebsiella pneumoniae (PRIMERS I).

242 sis of ES PspCN, a CFH-binding Streptococcus pneumoniae protein domain, binds CFH tightly and increas

243 Several Streptococcus pneumoniae proteins play a role in pathogenesis and are

244 in blepharitis; Staphylococci, Streptococus pneumoniae, Pseudomonas aeruginosa, Klebsiella pneumonia

245 ia coli, Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureu

246 ssion electron microscopy, we showed that S. pneumoniae rapidly adhered to and invaded cardiomyocytes

247 Pneumococcus (Streptococcus pneumoniae) remains a significant cause of morbidity and

248 A- and B-site SczA mutant variants impact S. pneumoniae resistance to zinc toxicity and survival in i

249 eningitidis (N. meningitidis), Streptococcus pneumoniae (S. pneumoniae), and Haemophilus influenzae t

250 850 (37%) of 2301 K pneumoniae samples and 77 (19%) of 402 E coli samples we

251 A model is proposed for S. pneumoniae SczA function in which both A- and B-sites we

252 onized the NPs of adult C57BL/6 mice with S. pneumoniae serotype (ST) 6A or 8 and then coinfected the

253 Streptococcus pneumoniae serotype 1 is one of the leading causes of in

254 Using the Streptococcus pneumoniae serotype 2 CPS, which is synthesized by the w

255 Streptococcus pneumoniae serotype 3 strains emerge frequently within c

256 Streptococcus pneumoniae serotype 35B is a nonvaccine serotype associa

257 immune response against native CPS using S. pneumoniae serotype 5 (ST-5), a problematic CPS componen

258 creened for rectal and throat carriage of K. pneumoniae shortly after admission.

259 pneumococcal disease caused by Streptococcus pneumoniae Some components of the S. pneumoniae glycocon

260 Populations of Streptococcus pneumoniae (SP) are typically structured into groups of

261 Streptococcus pneumoniae (SP) is a pathogenic bacterium and a major ca

262 13 of the over 90 serotypes of Streptococcus pneumoniae (Sp), so nonvaccine serotypes are a major obs

263 rtant human pathogens, such as Streptococcus pneumoniae (Sp).

264 an epidemic multidrug-resistant clone of K. pneumoniae (ST258).

265 Of the 15 K. pneumoniae strains detected in the study, four were dete

266 The time-scaled phylogeny suggested that K. pneumoniae strains isolated during the study period may

267 ary 2013, twenty-one multi-drug resistant K. pneumoniae strains, were collected from patients hospita

268 n challenged intratracheally with Klebsiella pneumoniae, Streptococcus pneumoniae, or lipopolysacchar

269 the immunochromatographic (ICT) BinaxNow S. pneumoniae test (composite diagnostic) was positive.

270 shown here through functional studies in S. pneumoniae that an unannotated homodimeric TetR from S.

271 CozE is a member of the MreCD complex of S. pneumoniae that directs the activity of PBP1a to the mid

272 hogens, Staphylococcus aureus and Klebsiella pneumoniae, that utilize this metal nutrient during infe

273 e upon high-dose pulmonary challenge with S. pneumoniae The cPLA2alpha-deficient mice also suffered n

274 Streptococcus pneumoniae (the pneumococcus) is a human pathogen, accou

275 Streptococcus pneumoniae (the pneumococcus) is the leading cause of co

276 Even in the vaccine era, Streptococcus pneumoniae (the pneumococcus) remains a leading cause of

277 isite for the human pathobiont Streptococcus pneumoniae (the pneumococcus) to cause severe invasive i

278 f bacterial species, including Streptococcus pneumoniae, the prevalence of resistance has remained re

279 uence type 258 (ST258) lineage of Klebsiella pneumoniae There was very little evidence of extensive h

280 The ratio of K pneumoniae to E coli was 11:1.

281 Hence, LTA is important for S. pneumoniae to establish systemic infections, and TacL re

282 oculated with either live or dead Klebsiella pneumoniae to induce either lung infection or lung infla

283 l colonisation model, black carbon caused S. pneumoniae to spread from the nasopharynx to the lungs,

284 s in a model of lung infection by Klebsiella pneumoniae Transferring serum from Ig-deficient mice to

285 the pattern of disease due to Streptococcus pneumoniae, trends in the serotype of invasive pneumococ

286 NA from Staphylococcus aureus and Klebsiella pneumoniae, two pathogens commonly related to neonatal s

287 e capsular polysaccharide from Streptococcus pneumoniae type 37, which consists of a beta-(1 --> 3)-l

288 by S. pneumoniae adhesins, we showed that S. pneumoniae uptake by cardiomyocytes is not through the w

289 Pneumoniae, using flow cytometry, reverse-transcription

290 the common human sepsis pathogen Klebsiella pneumoniae via the airways to induce pneumonia-derived s

291 enus Neisseria and the species Streptococcus pneumoniae was associated with lower EAC risk.

292 M. pneumoniae was detected by real-time PCR in 175 (5.8%) s

293 S. pneumoniae was detected in the myocardium of all NHPs wi

294 reduce bacterial burden in vivo, Klebsiella pneumoniae was injected into the tail veins of rats and

295 tion was identified in 59 (15.7%) Klebsiella pneumoniae was isolated in 83.2%; surgical site infectio

296 In Streptococcus pneumoniae, we find a genomically and ecologically disti

297 e use and PCV7 and PCV13 introductions on S. pneumoniae were associated with changes in macrolide res

298 ndophthalmitis is associated with Klebsiella pneumoniae whereas Coagulase negative Staphylococci and

299 alis, Pseudomonas aeruginosa, and Klebsiella pneumoniae, which are frequently implicated in nosocomia

300 the initial interactions of heart-invaded S. pneumoniae with cardiomyocytes remain unclear.