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1 , grade 2 hyperthyroidism, recurrent grade 4 pneumonitis).
2 b, and one treatment-related death occurred (pneumonitis).
3 irl with fire-eater's pneumonia (hydrocarbon pneumonitis).
4 of patients) occurred, each associated with pneumonitis.
5 TH17-mediated lung disease, hypersensitivity pneumonitis.
6 tive pulmonary disease, and hypersensitivity pneumonitis.
7 rectivirgula in a model of hypersensitivity pneumonitis.
8 nic rejection after IS withdrawal because of pneumonitis.
9 the treatment of a mouse model of autoimmune pneumonitis.
10 of fibrosis in experimental hypersensitivity pneumonitis.
11 One patient in each arm had fatal pneumonitis.
12 gen exposure known to cause hypersensitivity pneumonitis.
13 d adequate organ function, and no history of pneumonitis.
14 e of IL-17A in experimental hypersensitivity pneumonitis.
15 tial pneumonia, and chronic hypersensitivity pneumonitis.
16 mortality in a CD8+ T cell-specific model of pneumonitis.
17 , consistent with more severe alveolitis and pneumonitis.
18 II BMT mice are only modestly protected from pneumonitis.
19 8% grade 3 esophagitis, and 7% grade 3 to 4 pneumonitis.
20 ly ill patients and can lead to pneumonia or pneumonitis.
21 kine in fibrotic disease and likely promotes pneumonitis.
22 ontrol microbial Ag-induced hypersensitivity pneumonitis.
23 mucositis; however, four patients developed pneumonitis.
24 odel of B. subtilis-induced hypersensitivity pneumonitis.
25 had grade 3 toxicities including one grade 3 pneumonitis.
26 rom SARS-CoV-infected aged mice that develop pneumonitis.
27 utation developed autoimmune myocarditis and pneumonitis.
28 ration pneumonia or non-bacterial aspiration pneumonitis.
29 There were no cases of radiation pneumonitis.
30 One patient died due to ADV pneumonitis.
31 ival in people with chronic hypersensitivity pneumonitis.
32 s, catheter-related infections, and possible pneumonitis.
33 cells and protect mice from fatal autoimmune pneumonitis.
34 umber of HLA mismatches, and cytomegalovirus pneumonitis.
35 ctions, acute rejection, and cytomegalovirus pneumonitis.
36 ologic features consistent with interstitial pneumonitis.
37 ents died from probable radiation-associated pneumonitis.
38 f lung injury to a neutrophilic interstitial pneumonitis.
39 he beta3-/-LDLR-/- mice due to noninfectious pneumonitis.
40 a case each of cytomegalovirus retinitis and pneumonitis.
41 r, malaise, cough, dyspnea, and interstitial pneumonitis.
42 ldren with cellular nonspecific interstitial pneumonitis.
43 al desquamative and nonspecific interstitial pneumonitis.
44 ction with the C. trachomatis agent of mouse pneumonitis.
45 sen based on the estimated risk of radiation pneumonitis.
46 cause of morbidity and mortality from viral pneumonitis.
47 he 49 patients with non-bacterial aspiration pneumonitis.
48 ical but severe varicella-zoster virus (VZV) pneumonitis.
49 d safe in T cell-deficient patients with RSV pneumonitis.
50 ly infected with C. trachomatis strain mouse pneumonitis.
51 occurred over time in patients who developed pneumonitis.
52 , albeit with a potential high risk of fatal pneumonitis.
53 8% (95% CI, 0.4%-1.2%) for grade 3 or higher pneumonitis.
54 .6%; P < .001) but not for grade 3 or higher pneumonitis.
55 rse events (AEs); 7% of patients (n = 4) had pneumonitis.
56 sensory neuropathy, and one case of grade 4 pneumonitis.
57 of the scurfy donor, including hepatitis and pneumonitis.
58 ilimumab 1 mg/kg died from treatment-related pneumonitis.
59 including one patient from bleomycin-induced pneumonitis.
60 are no biomarkers that can predict radiation pneumonitis.
61 ed and were attributed to treatment-emergent pneumonitis.
62 signaling and protect from bleomycin-induced pneumonitis.
63 PAR1 to ERK, and inhibits bleomycin-induced pneumonitis.
64 in the use of CT or PET to predict radiation pneumonitis.
65 had higher rates of grade 2 or greater acute pneumonitis (1.2% vs. 0.2%, P=0.01) and lymphedema (8.4%
66 .6% vs 1.6%; P < .001) and grade 3 or higher pneumonitis (1.5% vs 0.2%; P = .001) in melanoma, with 1
67 .1% vs 1.6%; P = .002) and grade 3 or higher pneumonitis (1.8% vs 0.2%; P < .001) compared with melan
70 11%; P = .03]), while rates of grade 3 to 4 pneumonitis (12% vs 9%; P = .12) and esophagitis (23% vs
74 daily group; p=0.85) and grade 3-4 radiation pneumonitis (4 [3%] of 254 vs 4 [2%] of 246; p=0.70).
75 CC was higher than in melanoma for all-grade pneumonitis (4.1% vs 1.6%; P < .001) but not for grade 3
78 IMRT was associated with less >/= grade 3 pneumonitis (7.9% v 3.5%, P = .039) and a reduced risk i
79 ncluded liver function test elevation (14%), pneumonitis (9%), diarrhea (4%), nausea (4%), fatigue (4
80 xel included febrile neutropenia (10.9%) and pneumonitis (9.6%); 28.8% of patients were hospitalized
82 d a multifocal mononuclear cell interstitial pneumonitis, accompanied by multinucleated syncytial cel
83 Three deaths were attributed to treatment (pneumonitis, acute respiratory failure, and cardiovascul
89 pare the incidence of PD-1 inhibitor-related pneumonitis among different tumor types and therapeutic
91 RT was associated with lower rates of severe pneumonitis and cardiac doses in NRG Oncology clinical t
92 ed, including adults with usual interstitial pneumonitis and children with cellular nonspecific inter
93 athological findings, including interstitial pneumonitis and consolidation, is also remarkably reduce
94 e IPF compared with nonspecific interstitial pneumonitis and controls, which rose sharply during an a
95 in an enhanced immune-mediated interstitial pneumonitis and delayed clearance of SARS-CoV from the l
96 diotherapy is a mainstay for cancer therapy, pneumonitis and fibrosis constitute dose-limiting side e
97 ave also developed a mitigator for radiation pneumonitis and fibrosis that can be started as late as
98 of treatment-related adverse events (grade 4 pneumonitis and grade 4 thrombocytopenia) and subsequent
99 fection with the Chlamydia trachomatis mouse pneumonitis and L3 serovars and to Chlamydia pneumoniae.
104 ranscript in AECs enhanced radiation-induced pneumonitis and pulmonary fibrosis, and increased the ex
108 Using a nonlymphopenic model of autoimmune pneumonitis and T(Reg) with known Ag specificity, in thi
110 ry fibrosis in experimental hypersensitivity pneumonitis and to determine the main inflammatory cell
111 rring diagnosis of desquamative interstitial pneumonitis and who were older than 10 years at the time
114 gnised expertise in chronic hypersensitivity pneumonitis, and further research and studies at other c
115 biopsy shows findings of usual interstitial pneumonitis, and he has no identifiable cause for pulmon
116 p of the spleen by macrophages, interstitial pneumonitis, and increased numbers of immature myeloid c
117 ntly diagnosed with chronic hypersensitivity pneumonitis, and most of these cases were attributed to
119 ointestinal ulcers, cholecystitis, radiation pneumonitis, and radioembolization-induced liver disease
124 r latent viral load, BMT mice develop severe pneumonitis associated with reduced oxygen saturation, f
126 cterial aspiration pneumonia from aspiration pneumonitis based on quantitative bronchoalveolar lavage
127 ed as a result of autoimmune myocarditis and pneumonitis before developing renal disease or the syste
129 -forming units (IFU) of C. trachomatis mouse pneumonitis biovar (MoPn) and were euthanized at 10 days
131 mice infected intravaginally with the mouse pneumonitis biovar of Chlamydia trachomatis became infer
133 hocytic alveolitis, lymphocytic interstitial pneumonitis, bronchoalveolar obliterans organizing pneum
134 ronavirus (SARS-CoV), primarily present with pneumonitis but may also develop hepatic, gastrointestin
135 atients had no evidence for hypersensitivity pneumonitis, but 70% of cases had a personal or family h
136 rine models of experimental hypersensitivity pneumonitis, but its role in the development of pulmonar
137 gnificantly protected from the hepatitis and pneumonitis, but not the dermatitis, induced by adoptive
138 fibrosis (IPF) and chronic hypersensitivity pneumonitis can be indistinguishable; the need to elimin
140 role in the development of hypersensitivity pneumonitis caused by microbial Ags and that inhibition
141 of the current knowledge on hypersensitivity pneumonitis caused by the occupational environment and t
142 influenza A virus causes an acute, transient pneumonitis characterized by the massive infiltration of
143 urrent diagnosis of chronic hypersensitivity pneumonitis (cHP) involves considering a combination of
144 bined UCSF and UTSW chronic hypersensitivity pneumonitis cohort, we saw associations between extent o
145 copies/microg human DNA for 12 subjects with pneumonitis compared to 91 copies for 31 subjects withou
146 limited the rates of clinically significant pneumonitis, dose-limiting toxicity occurred and was dom
147 infections and occupational hypersensitivity pneumonitis due to metalworking fluid (MWF) exposures.
148 adverse effects, such as fibro-interstitial pneumonitis due to the acquisition of activated myofibro
150 thought to have died from grade 5 radiation pneumonitis during the study; however, this adverse even
151 e found in incidence of acute skin reaction, pneumonitis, dyspnea, cough, dysphagia, or neutropenia.
152 rhoea, decreased appetite, hyponatremia, and pneumonitis (each in two [1%]) in those given pembrolizu
153 ell-characterized murine models of radiation pneumonitis/fibrosis to compare and contrast differentia
155 luding: fatigue (five [4%] of 117 patients), pneumonitis (four [3%]), and diarrhoea (three [3%]).
156 ia (five [10%] and two [10%], respectively), pneumonitis (four [8%] and none, respectively), oedema (
157 terstitial pneumonia, 16 as hypersensitivity pneumonitis, four as sarcoidosis, four as respiratory br
159 and 11 years) with desquamative interstitial pneumonitis had ABCA3 mutations identified on both allel
160 The prevalence of lymphocytic interstitial pneumonitis had also dropped significantly following int
161 he 20 patients with chronic hypersensitivity pneumonitis had histopathological features on surgical l
162 ressive agents, had no active non-infectious pneumonitis, had no uncontrolled thyroid dysfunction or
163 ents requiring mechanical ventilation due to pneumonitis have a particularly poor outcome, and our fi
172 re in patients with chronic hypersensitivity pneumonitis (HP) the computed tomographic (CT) imaging f
175 luded esophagitis in 14 v nine patients, and pneumonitis in 0 v 6 patients for HART and qdRT, respect
176 rminated early because of treatment-emergent pneumonitis in 18% of patients (severe in 11 of 12 cases
178 induce arthritis, ileitis, and interstitial pneumonitis in BALB/c ZAP70 (W163C)-mutant (SKG) mice vi
180 is an opportunistic pathogen that can cause pneumonitis in immunodeficient people such as AIDS patie
181 ariable analyses demonstrated higher odds of pneumonitis in NSCLC for all-grade (odds ratio [OR], 1.4
182 ls, but not B cells, prevented hepatitis and pneumonitis in RAG(-/-) recipients of scurfy lymphocytes
185 locus was a significant risk factor for CMV pneumonitis in recipients exposed to CMV before transpla
187 n that excessive T cell activity can mediate pneumonitis in the setting of influenza infection, and d
190 mouse model of experimental hypersensitivity pneumonitis in which IL-17A was inhibited or neutrophils
192 +) bone marrow cells induced myocarditis and pneumonitis in WT;MRL(+/+) mice, despite a dramatic up-r
193 plantation patients who develop interstitial pneumonitis include idiopathic pneumonia syndrome and br
194 red in 15 (5%) of 310 treated patients, with pneumonitis, increased aspartate aminotransferase, incre
195 of bleomycin-treated WT mice display: severe pneumonitis; increased generation of superoxide; vascula
197 rom patients with RA-associated interstitial pneumonitis (IP) were examined by immunohistochemistry.
198 rammed cell death 1 (PD-1) inhibitor-related pneumonitis is a rare but clinically serious and potenti
203 greement for a diagnosis of hypersensitivity pneumonitis is low, highlighting an urgent need for stan
207 Other manifestations include eosinophilic pneumonitis, localized myositis, folliculitis, erythema
208 astatic pulmonary neoplasms, postobstructive pneumonitis, lung abscess, and occasionally empyema of m
209 ars]), and 192 with chronic hypersensitivity pneumonitis (men, 76; women, 116; median age, 66 years [
210 tion by a H3N2 subtype in a murine influenza pneumonitis model but was not effective in preventing pn
211 ding frames (ORFs) from C. trachomatis mouse pneumonitis (MoPn) genomic and plasmid DNA and tested it
212 eparation of the Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP) a
213 es (MAbs) to the Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP) w
214 eparation of the Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP),
215 rified and refolded the C. trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP).
216 ome sequences of Chlamydia trachomatis mouse pneumonitis (MoPn) strain Nigg (1 069 412 nt) and Chlamy
217 aths (5%) occurred on therapy as a result of pneumonitis (n = 1), stroke (n =1), and heart failure (n
219 ort, and grade 3 colitis (n=1 [6%]), grade 3 pneumonitis (n=1 [6%]), grade 3 fatigue (n=1 [6%]), grad
220 equent diagnosis of chronic hypersensitivity pneumonitis: nine patients had positive bronchial challe
221 r [7%]), diarrhoea (five [10%] vs one [2%]), pneumonitis (none vs five [9%]), stomatitis (none vs fiv
223 organizing pneumonia (BOOP) and interstitial pneumonitis occurred at 4 to 6 weeks, and 6 to 12 weeks,
230 related to either drug, and one death due to pneumonitis occurred in the erlotinib plus cabozantinib
234 tigue (one patient given 30 mg/day), grade 3 pneumonitis (one given 60 mg/day), and grade 4 thrombocy
236 ts of patients with chronic hypersensitivity pneumonitis, one from the University of California San F
237 There was one grade 5 adverse event (AE) of pneumonitis, one grade 4 thrombosis, and nine other grad
238 sy that was consistent with hypersensitivity pneumonitis; one was IgG positive plus had greater than
240 t of severe clinical manifestations, such as pneumonitis or eye complications; (ii) patients with a p
243 .60-5.08; P < .001) and in RCC for all-grade pneumonitis (OR, 1.59; 95% CI, 1.32-1.92; P < .001) comp
244 , 1.08-1.89; P = .005) and grade 3 or higher pneumonitis (OR, 2.85; 95% CI, 1.60-5.08; P < .001) and
245 , 1.69-2.50; P < .001) and grade 3 or higher pneumonitis (OR, 2.86; 95% CI, 1.79- 4.35; P < .001).
247 e of 192 (4.7%) had chronic hypersensitivity pneumonitis (P < .001), and 27 of 244 (11.1%) had nonspe
250 dnTGFbetaRII are largely protected from the pneumonitis phenotype, whereas mice with CD11c-dnTGFbeta
251 G at the onset of clinical disease, subacute pneumonitis, rapid onset of diffuse alveolar edema in th
252 (1.5% vs 0.2%; P = .001) in melanoma, with 1 pneumonitis-related death during combination therapy.
255 al lung diseases, including hypersensitivity pneumonitis, respiratory bronchiolitis-associated inters
256 t reported pediatric cases, hypersensitivity pneumonitis results from exposure to avian antigens, but
257 20 was associated with increased >/= grade 3 pneumonitis risk on multivariable analysis ( P = .026).
258 r associations with chronic hypersensitivity pneumonitis risk, survival, and clinical, radiographic,
261 ern consistent with chronic hypersensitivity pneumonitis); seven were IgG positive plus had histopath
263 combination between the C. trachomatis mouse pneumonitis strain and the C. pneumoniae horse N16 strai
265 al in patients with chronic hypersensitivity pneumonitis suggest shared pathobiology with IPF, and mi
266 cterium avium complex, lymphoid interstitial pneumonitis, systemic fungal infection, cytomegalovirus
267 50 in patients with chronic hypersensitivity pneumonitis than in healthy controls (24.4% in UCSF and
269 we have shown in a model of hypersensitivity pneumonitis that Th1-biased C57BL/6 mice are susceptible
271 genetically identical mice varied from mild pneumonitis to severe acute lung injury with extensive p
272 creased lipase (three [8%] and no patients), pneumonitis (two [5%] and one [3%] patients), adrenal in
273 s before bronchoscopy in those subjects with pneumonitis versus 0 days in those without (P=0.004).
274 from both models surviving high-fat feeding, pneumonitis was absent, but aortic atherosclerosis was 2
277 nce: The incidence of PD-1 inhibitor-related pneumonitis was higher in NSCLC and RCC and during combi
278 These results suggest that delayed-onset CMV pneumonitis was independently associated with an increas
286 found that the severity of hypersensitivity pneumonitis was unaffected by vancomycin, but increased
287 Toxicity, especially myelosuppression and pneumonitis, was more pronounced in the elderly patients
288 ith ALI and lungs from mice with LPS-induced pneumonitis, we found that pulmonary SDF-1 expression in
289 established murine model of hypersensitivity pneumonitis, we repeatedly exposed C57BL/6 mice to Sacch
290 ocytic bronchiolitis, BOOP, and interstitial pneumonitis were directly associated with the developmen
293 in severities in alveolitis and interstitial pneumonitis when each of the three variants was compared
294 and head and neck cancer develop aspiration pneumonitis, which is usually caused by organisms living
295 (IPF) or chronic (fibrotic) hypersensitivity pneumonitis, which suggests these disorders share risk f
298 g to patients' stratified risk for radiation pneumonitis with total RT doses ranging from 57 to 85.5
299 zed by viremia in the presence or absence of pneumonitis, with viral loads higher in the lung airways
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