ライフサイエンスコーパス: point to

1 thod correlated with the BLI findings, which points to (19)F MRI as a reliable method with which to t

2 entage points (95% CI, -19 to 4.3 percentage points) to 25 percentage points (CI, 14 to 35 percentage

3 ess severe in the PCI group at all follow-up points to 3 years.

4 Some studies point to a beta-helical arrangement, whereas others sugg

5 Collectively, our data point to a biologically important function of ALCAM in m

6 This might point to a ceiling effect for enteral protein intake wit

7 These data point to a complex but not sustainable integration of be

8 Together, our analyses point to a complex origin for the sex chromosome of C. g

9 In addition, our results point to a critical role for a single amino acid within

10 Separate lines of evidence point to a critical role of the primary motor cortex (M1

11 ns are linked to amyloid pathology in PD and point to a difference in the underlying pathophysiologic

12 mic change in mammalian sperm methylomes and point to a divergence in trans-epigenetic mechanisms tha

13 Overall, the data point to a dynamic selectivity filter that may serve as

14 ent the CDK10 loss-of-function phenotype and point to a function for CDK10 in transducing signals rec

15 spectroscopic studies, the results together point to a heterolytic dissociation mechanism of H2 over

16 Such lipid changes point to a hydrophobic phenotype for M. tuberculosis sen

17 r) and dissolved organic matter in the ocean point to a marine source for the measured OVOCs.

18 Our results point to a model in which MLCK and ROCK regulate periphe

19 The findings point to a model of social categorization in which occas

20 of CoRAs and FIs in antiviral therapies and point to a multifaceted role for chemokine receptor bind

21 ar, but the majority of longitudinal studies point to a negative exponential progression pattern of d

22 genic potential of this cell population, and point to a neural crest origin of dentine throughout the

23 mistry results of NH4(+) in these electrodes point to a new paradigm of NH4(+) -based energy storage.

24 These data point to a new type of protumorigenic CAF in the tumor m

25 These collective findings point to a novel glycosylation-dependent mechanism that

26 Collectively, these results point to a novel role for EYS in maintaining the morphol

27 Recent findings point to a novel role of apurinic/apyrimidinic endonucle

28 inus alpinus) and increased diatom diversity point to a positive ecosystem response during the same p

29 Recent findings point to a possible anatomical segregation, with cortica

30 ficient in H3K4 monomethylation activity and point to a possible role for H3K4me1 on cis-regulatory e

31 fficient to disrupt normal cell function and point to a possible role for SGs in cargo transport and/

32 Our data also point to a potential biomarker of target engagement for

33 bility in humans, the findings of this study point to a potential mechanism underlying neurological d

34 Together, these data point to a potential mechanistic switch between replicat

35 Further, initial simulation studies point to a potential positive effect on patient outcome

36 ng studied, and the currently available data point to a relevant clinical utility of this imaging tec

37 These findings point to a role for neuroscience in shaping long-standin

38 These results point to a role for PI(3,4)P2 in the phenotype caused by

39 y mutated CMGs (KMT2D, CREBBP, and EZH2) and point to a role for these events in modifying normal B-c

40 transcriptomic analyses during metamorphosis point to a role for thyroid hormone and retinoic acid si

41 and observed IQD-specific MT patterns, which point to a role of IQDs in MT organization and dynamics.

42 These findings point to a role of vitamin D and the VDR in modulating a

43 These findings point to a sex difference in NRF2 responsiveness that ne

44 uickly as possible from the central fixation point to a specified target located 20 degrees , 30 degr

45 These concurrent variations point to a unique process of temperature-pressure increa

46 Notably, multiple studies point to a unique role for CD57(+) NK cells in cancer im

47 Finally, Zbtb11 mutant rescue experiments point to a ZBTB11-regulated TP53 requirement in developm

48 These simulations pointed to a key role for an intramolecular interaction

49 Mycobacterium tuberculosis growth inhibitor, pointed to a mechanism involving a scaffolding protein,

50 A fluorescent protein-tagging study pointed to a peroxisomal location of CrACX2.

51 Evidence has pointed to a potential role for EMCN in angiogenesis but

52 ly explicit modeling of leaf water transport pointed to a role for reduced membrane conductivity cons

53 iginating on the outer periclinal cell face, pointing to a cell-directed, rather than self-organizing

54 ling of GJs in neurons and other cell types, pointing to a cellular mechanism for therapeutic interve

55 lates invasion through extracellular matrix, pointing to a critical role in secretion.

56 -outcome contingencies after their reversal, pointing to a critical role of the LHb and of its inputs

57 ignment was observed in the <111> directions pointing to a key driving mechanism for the formation of

58 ASs were associated with ledipasvir failure, pointing to a limited efficacy of ledipasvir in patients

59 via remote sensing and inversion modelling, pointing to a major gap in our understanding of the cont

60 the presence of the chemoattractant serine, pointing to a physiological relevance of the observed th

61 TP and the tuberous sclerosis complex (TSC), pointing to a potential link between growth signals and

62 of other authors on the paper being female, pointing to a potential role of female PIs in influencin

63 genous long terminal repeat (LTR) sequences, pointing to a select role of BRD4S-BRG1 complexes in gen

64 m, with a smaller decrease at deeper depths, pointing to a single mechanism for slab stagnation and p

65 cked the conversion of FAPs into adipocytes, pointing to a strategy to combat fatty degeneration of s

66 This dimerization points to a certain degree of regioselectivity, leading

67 arding clinical utility, increasing evidence points to a change in diagnosis via amyloid imaging in a

68 Growing evidence points to a disruption of cortico-thalamo-cortical circu

69 ly studied in isolation, increasing evidence points to a fundamental connection between these behavio

70 This points to a key adaptive role for regulatory changes in

71 Growing evidence points to a key role for somatostatin (SST) in schizophr

72 The discovery points to a mechanism of nucleic acid sensing regulation

73 However, the inhalation exposure assessment points to a minimum risk for human health at both sites.

74 This finding points to a new route towards controllable synthesis of

75 Prior research points to a positive concurrent relationship between rea

76 This enhancement points to a regulatory role for noradrenergic neurotrans

77 tforms in both non-human primates and humans points to a role for polyclonal vaccine-induced antibody

78 missense mutations in five ARS genes, which points to a shared mechanism of disease.

79 Together, our data points to a simple unifying mechanism governing the asse

80 Emerging evidence points to a strong association between sex and gut micro

81 ot rely on kinetic parameters, and therefore points to a theoretical framework for describing a broad

82 ino acids long, but a large body of evidence points to Abeta(1-42) rather than Abeta(1-40) as the cyt

83 These data point to ACC MKP-1 as a key factor in the pathophysiolog

84 merated here will serve as a useful starting point to address these challenges.

85 ed Lewy bodies in the neocortex, others have pointed to alpha-synuclein pathology in the hippocampus.

86 ll, the 8-10% resistance without markers may point to alternative mechanisms of resistance.

87 Our results point to AMO(+) NAO(+) and AMO(-)NAO(-) phases as being

88 Accumulating evidence points to amplification of the progesterone signaling ax

89 lence on motile phytoplankton, these results point to an active adaptation of H. akashiwo to increase

90 Our results point to an ancient role for brachyury in morphogenesis,

91 Our results point to an EsRalpha-dependent, reciprocal interaction b

92 In conclusion, our findings point to an extra risk for individuals with combined vul

93 Our data point to an idiopathic, genetic, or drug-induced hypergl

94 Several lines of emerging data point to an imbalance between neuronal excitation and in

95 enotypes in mouse models of amyloidosis that point to an important role for TREM2 in regulating the r

96 individual differences in imagery vividness point to an important role of the early visual cortex.

97 The results point to an innovative means for generating electrical p

98 Our data thus point to an instructional role for energy flux in the ex

99 Our results point to an intimate relationship between triplet-triple

100 Our results point to an intriguing coupling between 3D chromatin top

101 Mouse organoid experiments point to an intrinsic role for Ret in promoting epitheli

102 To support their hypothesis, the authors point to an inverse correlation between latitude and the

103 The RNA sequencing also pointed to an essential role of the Sox18 transcription

104 Analysis of beneficial mutations pointed to an unexpected, long-range allosteric pathway

105 o)hemiacetal, led to even higher activities, pointing to an alternative mechanism of activation.

106 was enhanced in Panx1 (del) Apoe (-/-) mice, pointing to an atheroprotective role for Panx1 in endoth

107 MKP-1 attenuates depressive-like behaviors, pointing to an important role of this phosphatase in dep

108 Fossil evidence points to an African origin of Homo sapiens from a group

109 t increase of ALS incidence in men and women points to an effect of exogenous factors with a differen

110 ariants in the sarcomere genes MYH6 and MYL4 points to an important role of myocardial structure in t

111 Mounting evidence points to an intricate relationship between DSBs and tra

112 These data point to "anti-TNFalpha" drugs as potential treatments f

113 spectral response of structured samples and points to appropriate models for recovering accurate che

114 regulation as it pertains to speciation and point to areas that could benefit from future research.

115 morphological change when restricting pacing points to areas of voltage >0.5 mV.

116 Our findings point to AtPMEI10, AtPMEI11, and AtPMEI12 as mediators o

117 ic RAS to induce thyroid cell proliferation, pointing to ATXN7 as a previously unrecognized cancer ge

118 Our data point to Australia as an early reservoir, with transmiss

119 ted with different clinical characteristics, pointing to basophils as important players in CU pathoph

120 expression data of T2EC chicken erythrocytes pointed to BATF as a candidate novel regulator of erythr

121 of interest, thus giving chance for all data points to be propagated down the data analysis pipeline,

122 The affected genes additionally point to biological processes implicated in the interrog

123 sis, we allocated 3 points to pneumatosis, 2 points to blood in stool, and 1 point each to abdominal

124 INTERPRETATION: The data point to both a co-occurrence and a cycle of abuse, with

125 ce of groups 1 and 2 in the human population points to both forms of innate immune response to EBV ha

126 omical morphology model of SNS addiction and point to brain morphology similarities and differences b

127 ared to conventional thin-section histology, pointing to broad applications in both research and clin

128 iver identification and integrative analysis points to candidates of potential clinical relevance.

129 s in the understanding of percolation theory points to cation-disordered lithium-excess transition me

130 Together, our data point to Ccr7 as a critical host defense restriction fac

131 ing was associated with high levels of CDK6, pointing to CDK6 as a direct transcriptional target of t

132 xercise-induced pain have been developed and point to central mechanisms underlying this phenomena, s

133 Some preclinical studies have pointed to central sites in the brain and brainstem.

134 CXR/MRI, whereas U.S. guidelines preferably point to CHCT/MRI in patients with head and neck squamou

135 ted clinician-friendly dosing algorithms and pointed to circumstances where intravenous monotherapy m

136 d in the different studies, growing evidence points to clear benefits of lycopene in the maintenance

137 iseases and Crohn's disease as hubs and thus pointing to common inflammatory processes underlying dis

138 ere greatest at the peak of the outbreak and pointed to complex defense responses.

139 Finally, we point to creation of a built-in electric field as a key

140 ptors and ion channels, however new evidence points to critical effects on intra-neuronal microtubule

141 the presence of archaeological evidence that points to cultural exchange, and thus possible admixture

142 We used a sputum eosinophil 2% cut point to define subjects with either an eosinophilic (>/

143 W. smithii provides a unique starting point to determine if there are universal nonbiting gene

144 f insulin or glucose or both at various time points to determine insulin resistance.

145 Gene set enrichment points to differences in protein catabolism as one major

146 is review, we provide a forum and a starting point to discuss the idea that catalytic function alone

147 Identifying these sites can point to disease-associated transcriptional pathways, wi

148 Together, this points to dissociative OS-SET (SET to a sigma* orbital c

149 We assigned a specific number of points to each BE risk factor, and point totals (scores)

150 These data point to early life as a sensitive time during which die

151 Use of these same motifs as hinge points to enable such dynamic events as rotation of the

152 sults add to a growing body of evidence that points to epigenetic factors as one of the key determina

153 such as duration of therapy and optimal end points to evaluate efficacy of drugs in clinical practic

154 t torque on the nanosecond time scale, which points to exciting opportunities for ultrafast and novel

155 er access to newer therapies, an earlier end point to expedite clinical trials is needed.

156 ng the 11 historical antigenic drift events, pointing to experimentally validated mutations.

157 These studies will serve as a starting point to explore the nonlinear dynamics of atrial cells

158 stently with physiology, the genome analysis points to F. acidiphilum Y(T) having an obligate peptido

159 xations to adapt to the new optimal fixation points to faces.

160 developed an accompanying webserver with end-points to facilitate querying of the database.

161 body fat content in Asians, growing evidence points to factors other than body fat content and fat di

162 C, and corroborate previous clinical results pointing to finasteride as a novel therapeutic avenue to

163 ainly by biological function, these findings point to fine-tuned and interdependent functional roles

164 entified, including 9 low-frequency variants pointing to functional candidates.

165 The results point to further enhancements that could be obtained by

166 d by coxibs and those mediating CAD risk and points to further mechanisms, which are potentially resp

167 ent outcomes, identify gaps in evidence, and point to future priorities for global research.

168 op-associated neurodegenerative diseases and point to future therapeutic approaches to treat these di

169 ocusing on procedural and late outcomes, and pointing to future directions.

170 ng neuronal development and oxidative stress points to gamma-tubulin-2 prosurvival function.

171 ferences between fast- and slow-growing fish pointed to genomic regions likely involved in growth reg

172 ve patterns in the neighborhood of a tipping point to greatly reduced vaccine uptake and large epidem

173 Our observations point to GRFs as new multifaceted players in Ribi gene r

174 r phenotypic biomarkers across multiple time-points to guide disease-progressive interpretation.

175 These results point to HAT as implausible for the reaction with nitric

176 We also make it a point to highlight the aspects of mouse visual circuitry

177 Much genetic and physiologic evidence points to impaired arousal responses to hypercarbia and

178 for End-Stage Liver Disease (MELD) exception points to increase waitlist priority for liver transplan

179 x-(S/T)-P showed increased phosphooccupancy, pointing to increased activity of one or more MAP kinase

180 Investigation findings point to infection of the patient after exposure in or n

181 Increasing evidence points to inflammation as one of the key players in diab

182 Together, our studies point to IRE1alpha as an important node for posttranscri

183 atibility complex molecules, recent findings point to its broader biological roles.

184 CN as a potent regulator of angiogenesis and point to its potential as a new therapeutic target for a

185 f GPR64 expression in uterine decidual cells points to its potential physiological significance on de

186 These findings point to KA1-mediated intramolecular autoinhibition as a

187 f this loop as a hierarchical Bayesian model points to key computational quantities that inform a tax

188 lenging to identify, but once found they can point to larger networks of interactions, such as with p

189 The method maps multivariate data points to latent one-dimensional coordinates along their

190 These phase 3 trial results point to little benefit to current EGFR-targeted agents

191 rove circadian rhythms are prospective entry points to mitigate cardiometabolic disease risk.

192 We used 33,241 soil data points to model recent (1980-1999) global distributions

193 . cerevisiae we show that epistatic NEMs can point to modulators of genetic interactions.

194 Our data point to MTL tau pathology, particularly in the entorhin

195 ers from that uncovered in previous studies, pointing to multiple mechanisms for achieving fixed tran

196 ransmission beyond limited clonal outbreaks, points to multiple unsampled transmission chains through

197 trehalose taste perception modification, and point to necessary future directed sensory experiments n

198 and community effects of mass incarceration points to negative health impacts on the female partners

199 These findings point to neonicotinoids causing a reduced capacity of be

200 r ambient temperatures, these properties all point to NESMD as a promising solution for household- or

201 Findings point to neural signatures of risk for maintaining PTSD

202 th and extending previous findings, and they point to new target regions and avenues of study in TS.

203 of B cell differentiation by basophils could point to new therapeutic targets.

204 rstanding of the alloimmune response and are pointing to new ways to improve allograft outcomes in th

205 lay some physiological aspects of aging, and points to new approaches for pharmacological interventio

206 unable to transform like the wild type that point to novel regulation of PI3K signaling.

207 Our work has pointed to nuclear factor E2-related factor 2 (Nrf2) bei

208 er a range of water-activity values and time points to obtain a complete profile of the germination p

209 gh surprisingly few in number, these studies point to old age of TRF, low extinction and high speciat

210 Comparisons with nonhuman apes point to our early-emerging cooperative-communicative ab

211 Previous studies point to P limitation-induced changes in lipid compositi

212 KATP channel activity and insulin secretion point to participation of the cGMP/PKG and cAMP/PKA/Epac

213 on rates indicating metabolic depression and pointing to particular sensitivity of E. verrucosus to p

214 d WE on the IRE, which was used as reference point to perform the electro-oxidation of ethanol over a

215 hanoid ratios, and La-Ce-Sm ternary diagrams pointed to petroleum refineries as being largely respons

216 e ordinal NEC score analysis, we allocated 3 points to pneumatosis, 2 points to blood in stool, and 1

217 rowth and functions in parallel with spatial point-to-point mapping mechanisms.

218 The point-to-point target acquisition sessions began on Oct

219 These results point to possible depletion of GSH, an essential antioxi

220 Our results also point to potential novel mechanisms of integrating multi

221 dvances in preclinical translational science point to potential targets across multiple organ systems

222 gs identifying these Wolbachia effectors and point to potential, as yet uncharacterized, links betwee

223 ion of gamma activity after plasticity onset points to potential new mechanisms for the initiation of

224 bution to the aetiology of atopic eczema and pointing to potentially modifiable influences.

225 uble rnhAB mutants to translation inhibition points to R-loops as precursors for R-lesions.

226 Epidemiological studies point to race as a determining factor in cancer suscepti

227 yellow seed variants and a historical model point to recessive alleles in B1, D and G loci being res

228 We apply our module to identify the optimal point to redirect glycolytic flux into heterologous engi

229 bolic imaging using hyperpolarized pyruvate, points to reduced oxidative flux due to NAD(+) depletion

230 Gene expression studies point to regulation of cell cycle genes, muscle myosins,

231 cant fraction of CHD, while at the same time pointing to remarkable complexity in CHD genetics.

232 eduction of IS is required at different time points to rescue circadian behavior and memory.

233 epigenetic alterations in hematopoietic CDRs points to sets of genes that are tightly regulated in le

234 Taken together, these data point to several important physiological changes that co

235 This may point to sex differences in limbic brain regions.

236 Models and conductivities point to significant mobility increases induced by dopan

237 Our findings point to SNF as a mechanism for plants and ecosystems to

238 Our results point to social norms being on the basis of the generous

239 SOX9 as a key regulator of cardiac fibrosis, pointing to SOX9 as a potential therapeutic target for c

240 Mounting evidence points to specialized neuronal subtypes within the serot

241 at pleiotropy is a widespread phenomenon and points to specific instances of both agonistic and antag

242 of genes coordinately upregulated with IL-6 pointed to STAT4 and leukemia inhibitory factor (LIF) as

243 Our finding points to strategies to target the aberrant BRD4 signali

244 This study provides a starting point to study how RGB cone-specific transcription defin

245 Experimental time points to study the deuteration-labeling kinetics were o

246 tify MTSS1 as a new Akt2-regulated gene, and point to suppression of MTSS1 as a key step in the metas

247 KEY POINTS: To swallow food and liquid safely, airway protec

248 These findings point to the cognitive impairments caused by PCP arising

249 These results point to the commonality of enhancer-like promoters in t

250 rther study of erythrocyte vesiculation that point to the criticality of understanding the biochemica

251 Our results point to the crucial role of several dystrophin isoforms

252 Our data point to the existence of negative feedback loops betwee

253 er than estimates published before 2013, and point to the growing importance of hearing loss and glob

254 Therefore, our results point to the importance of cholinergic modulation in mPF

255 chlorophyll a Correlations with temperature point to the importance of environmental selection in st

256 These data point to the importance that quinidine, that in several

257 ed thalamo-frontal circuits in cognition and point to the MD as a potential therapeutic target for im

258 terobacteriaceae, these mechanistic insights point to the metabolism of epithelial cells as a possibl

259 ease, and several ongoing studies could soon point to the most important behavioural and physiologica

260 e transfer of small molecules into cells and point to the necessity for a more complex model.

261 emic influence to neurological disorders and point to the need for future studies to better define sp

262 These results point to the possibility that MOR and its downstream sig

263 These in vivo results point to the potential use of selective HDAC3 inhibitors

264 co-occurrence of clinical features that may point to the presence of chromosomal rearrangements as t

265 Several lines of evidence point to the presence of protective antibodies in health

266 Overall, our results point to the prognostic and therapeutic value of identif

267 These findings point to the soothing function of slow, affective touch,

268 of cisplatin in the human cochlea, and they point to the stria vascularis as an important therapeuti

269 The authors rightly point to the theoretical importance of interactions of s

270 dysfunction in ASD-related pathogenesis, and point to the Trio-Rac1 pathway at glutamatergic synapses

271 oth syngas and H2/CO2 (compared to fructose) point to the urea cycle, uptake and degradation of pepti

272 ctrometry of SIRT5-treated membrane proteins pointed to the electron transport chain, particularly Co

273 Although recent evidence has pointed to the existence of small open reading frame (sm

274 Previous reports pointed to the probable role of COPT2 in Au transport ba

275 uctivity deviates from this universal curve, pointing to the importance of thermal activation of carr

276 catatonic signs in an age-dependent manner, pointing to the involvement of myelin-producing oligoden

277 ely 7 d after birth, with a primary dendrite pointing to the molecular layer, but at this stage, with

278 tions (CNVs) have recently been linked to AC pointing to the need to determine the prevalence of CNVs

279 usive genes not detected in other subgroups, pointing to the potential for novel functions.

280 ontaining a human insulin promoter fragment, pointing to the responsible cis element.

281 n-regulation of inflammatory response genes, pointing to the suppression of nuclear factor kappa B-de

282 rase dispersion seen in the Col13a1-/- mice, pointing to the transmembrane form as the major conducto

283 st time proteins interacting with Nbeal2 and points to the dysregulation of the canonical signaling p

284 ence of these gene families in higher plants points to the existence of an intriguing regulatory netw

285 with ongoing behavior and plasma osmolality points to the existence of brain networks that integrate

286 is well characterized, accumulating evidence points to the existence of multiple, less well-defined l

287 Increasing evidence points to the importance of prion-like seeding as a mech

288 Research evidence increasingly points to the large impact of sleep disturbances on publ

289 on of HIV diagnosis among young participants points to the need for tailored long-term health-care an

290 a fear expression with averted gaze clearly points to the source of threat, direct-gaze fear renders

291 Our work points to the subtle adsorption-kinetics relationship in

292 s between health and segregation by nativity points to the wide range of experiences within the diver

293 ard to dynamics of the memory B cell subsets point to their role in the pathogenesis of HIV/SIV infec

294 By assigning hazard ratio (HR)-weighted points to these variables, three risk categories were de

295 th dilated and restrictive cardiomyopathies, pointed to this gene as an important cause of structural

296 Emerging evidence points to this reversible protein modification being an

297 gram distinct from a classical LPS response, pointing to unique P. falciparum-induced activation path

298 on as a means to regulate BRCA2 function and point to USP21 as a potential therapeutic target in BRCA

299 t during this period, the classic hypothesis pointed to vesicle depletion at the IHC as responsible f

300 Collectively, our results point to wall ingrowth deposition in PP TCs being under