ライフサイエンスコーパス: polio

1 disposal of all OPV after the eradication of polio.

2 red globally by epidemics of vaccine-derived polio.

3 ld Health Assembly's resolution to eradicate polio.

4 three districts of Pakistan at high risk of polio.

5 ncreased with a higher rate of reporting non-polio acute flaccid paralysis (AFP) (OR = 1.13, 95% CI 1

6 5% CI 1.02-1.26 for a 1-unit increase in non-polio AFP per 100,000 persons aged <15 years).

7 against risk of vaccine-associated paralytic polio and circulating vaccine-derived poliovirus.

8 $1.61 billion for the global eradication of polio and has committed to provide an additional $35 mil

9 Between 2004 and 2014, DDM supported 99 polio and nonpolio vaccination campaigns, disbursing mor

10 serve as a tool to aid in the eradication of polio and other infectious diseases for the improvement

11 controlled infections including smallpox and polio and that simple, effective treatment is not suffic

12 s that result in various diseases, including polio and the common cold.

13 The greatest reductions were noted for polio and tuberculosis at -3594 (95% CI -4811 to -2377;

14 such as tuberculosis, malaria, cholera, and polio, and biological threats, such as anthrax and plagu

15 er doses of acellular pertussis, inactivated polio, and diphtheria vaccines at 12 to 24 months of age

16 Nine polio areas of expertise were applied to broader immuniz

17 coverage cannot be attributed to the use of polio assets alone, 6 out of the 10 focus countries impr

18 rawal of its type 2 component, and (3) using polio assets to strengthen immunization systems in 10 pr

19 ude strengthening immunization systems using polio assets, introducing inactivated polio vaccine (IPV

20 Less time was spent on polio-associated activities in countries that had alread

21 itiative has reduced the global incidence of polio by 99% and the number of countries with endemic po

22 SMNet was created as a strategy to eradicate polio by engaging >7000 frontline social mobilizers to a

23 n teams provided significant feedback during polio campaigns and enabled supervisors to evaluate perf

24 on Initiative (GPEI) partners, the number of polio cases decreased by 99%.

25 Overall, in Pakistan the risk of polio cases was predicted to reduce between July-Decembe

26 To minimize risk of vaccine-derived polio countries using OPV were asked to dispose of all u

27 013-2018 (Endgame Plan) was developed to end polio disease.

28 akistan faces huge challenges in eradicating polio due to widespread poliovirus transmission and secu

29 e obvious similarities in strategies between polio elimination and measles and rubella elimination in

30 strategies in public health for its role in polio elimination in India.

31 The deputy incident manager of the National Polio Emergency Operations Centre was appointed the inci

32 nment engagement, and the establishment of a Polio Emergency Operations Centre.

33 lementation of the strategies set out in the polio emergency plan.

34 helpful in supporting further stages of the polio end game and other time-sensitive vaccine introduc

35 : Despite the challenges associated with the polio end-game in high-risk, conflict-affected areas of

36 Nigeria was one of 3 polio-endemic countries before it was de-listed in Septe

37 Nigeria, as one of 3 remaining polio-endemic countries, developed an emergency plan to

38 resources to provide technical assistance to polio-endemic countries.

39 campaigns in insecure and conflict-affected polio-endemic districts of Pakistan.

40 We review the lessons learned during the polio endgame about the role of subpopulations in sustai

41 ts by global partners to successfully launch polio endgame activities to permanently secure and susta

42 tant role in effective implementation of the polio endgame strategy and the national immunization str

43 iovirus vaccine (IPV) are major steps in the polio endgame strategy.

44 public health and called for a comprehensive polio endgame strategy.

45 maintenance of population immunity in a post-polio era.

46 obal Polio Eradication Initiative (GPEI) for polio eradication activities (hereafter, "GPEI-funded pe

47 Rotary volunteers have provided support for polio eradication activities and continue to this day by

48 munication initiatives aimed at highlighting polio eradication activities and the importance of immun

49 overnments and immunization professionals to polio eradication and an exemplary partnership between t

50 The Polio Eradication and Endgame Strategic Plan (PEESP) est

51 ed polio vaccine (IPV) as part of the Global Polio Eradication and Endgame Strategic Plan (the Endgam

52 The Polio Eradication and Endgame Strategic Plan 2013-2018 (

53 oral polio vaccine (OPV) associated with the Polio Eradication and Endgame Strategic Plan 2013-2018 b

54 The Polio Eradication and Endgame Strategic Plan 2013-2018 c

55 The Polio Eradication and Endgame Strategic Plan 2013-2018 w

56 to coordinate and oversee objective 2 of the Polio Eradication and Endgame Strategic Plan 2013-2018,

57 The requirements under objective 2 of the Polio Eradication and Endgame Strategic Plan 2013-2018-t

58 The Polio Eradication and Endgame Strategic plan outlines th

59 the necessary financial resources within the Polio Eradication and Endgame Strategic Plan timelines.

60 al partners to national staff as part of the Polio Eradication and Endgame Strategic Plan, 2013-2018.

61 ement and coordination of Objective 2 of the Polio Eradication and Endgame Strategic Plan.

62 y be drawn upon when bOPV is withdrawn after polio eradication but also could be relevant for other g

63 e STOP program and how it has contributed to polio eradication by building global public health workf

64 e Global Commission for the Certification of Polio Eradication certified the eradication of type 2 wi

65 h high coverage represents the root cause of polio eradication delays.

66 public health workforce capacity to support polio eradication efforts, including national STOP progr

67 e, Nigeria has been the focus of intensified polio eradication efforts.

68 applied to a global public health issue, the polio eradication Endgame plan.

69 tor immunization-system strengthening in the Polio Eradication Endgame Strategic Plan 2013-2018 (PEES

70 d health goals in ten focus countries of the Polio Eradication Endgame Strategic Plan: policy & strat

71 ccine (IPV) represents a crucial step in the polio eradication endgame.

72 tly secure and sustain the enormous gains of polio eradication forever.

73 ventable diseases that will endure after the polio eradication goal is achieved.

74 A key strategy for polio eradication has been the development of a skilled

75 ty systems are critical for all programs and polio eradication has illustrated these can be leveraged

76 tiative (GPEI) in certifying and maintaining polio eradication in a standardized, ongoing, and credib

77 rams in Africa that have benefitted from the polio eradication infrastructure.

78 personnel receiving funding from the Global Polio Eradication Initiative (GPEI) for polio eradicatio

79 The Global Polio Eradication Initiative (GPEI) has been in operatio

80 k of independent bodies to assist the Global Polio Eradication Initiative (GPEI) in certifying and ma

81 By 2000, with the support of the Global Polio Eradication Initiative (GPEI) partners, the number

82 s and setbacks in the 28 years of the Global Polio Eradication Initiative (GPEI), this article articu

83 ) is a fundamental cornerstone of the global polio eradication initiative (GPEI).

84 apacity as procurement agency for the Global Polio Eradication Initiative and Gavi, the Vaccine Allia

85 levant human resources and their role in the Polio Eradication Initiative and in RI.

86 d Somalia developed draft plans to integrate Polio Eradication Initiative assets, staff, structure, a

87 e technical requirements, the success of the polio eradication initiative depends on timely provision

88 The polio eradication initiative had major setbacks in 2003

89 ation Systems Management Group of the Global Polio Eradication Initiative has been useful to the NVI

90 The Global Polio Eradication Initiative has built an extensive infr

91 Despite major setbacks, the Global Polio Eradication Initiative has made substantial progre

92 The Global Polio Eradication Initiative has reduced the global inci

93 Strategic Plan 2013-2018 (PEESP), the Global Polio Eradication Initiative identified 1 indicator: 10%

94 had been made since the launch of the Global Polio Eradication Initiative in 1988.

95 The Polio Eradication Initiative in Nigeria, which started >

96 o (STOP) program began supporting the Global Polio Eradication Initiative in the Republic of South Su

97 As the global polio eradication initiative prepares to cease use of or

98 d partners for effective coordination of the polio eradication initiative program and harmonization o

99 e major challenges being faced in the Global Polio Eradication Initiative program is persistent refus

100 elays in implementing the switch, the Global Polio Eradication Initiative provided catalytic financia

101 one of the key criteria prompting the Global Polio Eradication Initiative to begin withdrawal of oral

102 enter, demonstrating the value of the Global Polio Eradication Initiative's legacy.

103 World Health Assembly established the Global Polio Eradication Initiative, which consisted of a partn

104 nd accurate laboratory results to the Global Polio Eradication Initiative.

105 liovirus type 2 during the next phase of the polio eradication plan.

106 HR) for polio, to monitor performance of the polio eradication program and guide the program in the a

107 ogram, and lessons learned from managing the polio eradication program greatly contributed to the spe

108 f global measles and rubella elimination and polio eradication strategies.

109 has enabled implementation of the endgame of polio eradication which calls for a phased withdrawal of

110 The partnerships that helped support polio eradication will need to consider funding to maint

111 relevant (policy and technical) documents on polio eradication, along with minutes and reports from c

112 o incorporate important lessons learned from polio eradication, and polio resources are concentrated

113 uild demand and trust for the last stages of polio eradication, as well as for other life-saving heal

114 nal, and international advocacy programs for polio eradication, assisting at immunization posts and c

115 when all OPVs are completely withdrawn after polio eradication, but also may offer a useful model for

116 y provides a substantial challenge to global polio eradication, having contributed to 73% of reported

117 Given the momentum gained toward polio eradication, these resources seem well positioned

118 iovirus endgame and efforts to ensure global polio eradication.

119 tion as we approach the endgame strategy for polio eradication.

120 clips and bulletins published in support of polio eradication.

121 cial for informing decisions aimed at global polio eradication.

122 xcrete vaccine-derived polioviruses threaten polio eradication.

123 introduced in mass campaigns to help achieve polio eradication.

124 engthening immunization programs, other than polio eradication.

125 Polio; eradication; transmission; heterogeneity.

126 amined the effect of spatial coupling on the polio extinction frequency in islands relative to larger

127 We found polio fadeout frequency to depend on both population siz

128 coverage in polio high-risk districts of 10 polio focus countries.

129 ication of poliovirus and the elimination of polio for all time.

130 tern Pacific Region (WPR) has maintained its polio-free status since 2000.

131 ved polioviruses is essential for creating a polio-free world, and eliminating that risk will require

132 To secure a polio-free world, the live attenuated oral poliovirus va

133 LPs, could be ideal candidate vaccines for a polio-free world.

134 eam some of the functions, to keep the world polio-free.

135 99% and the number of countries with endemic polio from 125 to 3 countries.

136 Eliminating the risk of polio from vaccine-derived polioviruses is essential for

137 As polio funding declines, it is time to take stock of the

138 e stock of the resources made available with polio funding in Africa and begin to find ways to keep s

139 By 2016, the annual incidence of polio had decreased by >99.9%, compared with 1988, and a

140 Its unwavering commitment to eradicate polio has been vital to the success of the program.

141 tussis-containing vaccine (DTP3) coverage in polio high-risk districts of 10 polio focus countries.

142 y-based health and immunisation camps during polio immunisation campaigns was successful in increasin

143 The legacy of polio in Africa goes far beyond the tragedies of million

144 The effect of climate variables on polio incidence was negligible, indicating that a climat

145 on coverage were the strongest predictors of polio incidence, however their relative effect sizes wer

146 gement of youth groups has a great future in polio interruption as we approach the endgame strategy f

147 When polio is finally gone, we will have the knowledge from t

148 rnalists Initiatives on Immunisation Against Polio (JAP), to develop communication initiatives aimed

149 ed, samples were shipped at 4 degrees C to a polio laboratory for concentration.

150 The Global Polio Laboratory Network (GPLN) began building in the la

151 As an example of how the polio legacy can create long-lasting improvements to pub

152 important piece in the documentation of the polio legacy in the Americas.

153 As part of polio legacy planning, we recommend the DDM as a model f

154 of health systems in the country as part of polio legacy planning.

155 However, it has also been implicated in a polio-like neurological disorder, acute flaccid myelitis

156 activities in 77 LGAs at very high risk for polio, located across 10 states in northern Nigeria.

157 predicting future cases, at a time when the polio map is shrinking.

158 ccine-preventable diseases (VPDs), including polio, measles and rubella, yellow fever, Japanese encep

159 se outbreak period, vaccination coverage for polio, measles, and yellow fever continued to decrease,

160 The incubation period for typhoid, polio, measles, leukemia and many other diseases follows

161 , Triple vaccine, Hepatitis B vaccine (HBV), Polio, Measles, Rubella, Mumps, trivalent MMR vaccine an

162 The National Stop Transmission of Polio (NSTOP) program was collaboratively established in

163 Paralytic polio once afflicted almost half a million children each

164 In June 2014, the Polio Oversight Board (POB) agreed to make available a m

165 pite tremendous efforts in the fight against polio, Pakistan bears the highest proportion of poliomye

166 n and poliomyelitis, it can be used to study polio pathogenesis and to assess the efficacy of candida

167 n and poliomyelitis, it can be used to study polio pathogenesis, candidate antiviral drugs, and the e

168 engaged with communities, and taken care of polio patients.

169 livery, and receipt of five infant vaccines: polio, pentavalent (diphtheria, tetanus, pertussis, hepa

170 The analysis illustrates that polio personnel in Northern Nigeria are used in increasi

171 The reports supported other polio program activities, such as review of microplans a

172 indicators were observed for the WHO-Nigeria polio program after implementation of a systematic accou

173 The new maps are useful to and used by the polio program as well as other public health programs wi

174 for more effective planning and analysis of polio program data.

175 ed a response to the outbreak relying on the polio program experiences and infrastructure.

176 The polio program in Nigeria has achieved unprecedented gain

177 The support from the polio program infrastructure, particularly the coordinat

178 the World Health Organization (WHO)-Nigeria polio program staff, as well as the program itself.

179 The legacy of the polio program will be the complete eradication of poliov

180 the availability of skilled personnel in the polio program, and lessons learned from managing the pol

181 rnal statistician (1:1:1) to receive routine polio programme activities (control, arm A), additional

182 sured by in-vitro neutralisation of a type 2 polio pseudovirus (PV2).

183 We assessed the impact of various polio-related interventions, to measure the contribution

184 A narrative analysis of polio-related program and other official documents was c

185 The types of non-polio-related tasks performed by GPEI-funded personnel v

186 Nigeria is among the 3 countries in which polio remains endemic.

187 lessons learned from polio eradication, and polio resources are concentrated in the countries with t

188 ine immunization in countries with extensive polio resources, and initiating activities to transition

189 ces, and initiating activities to transition polio resources, program experience, and lessons learned

190 f the states that commenced the provision of polio, RI, and other selected PHC services using the ded

191 During 2011-2014, Nigeria conducted serial polio seroprevalence surveys (SPS) in Kano Metropolitan

192 The results from the polio seroprevalence surveys conducted in Kano Metropoli

193 d humoral protection similar to tOPV against polio serotypes 1 and 3.

194 As part the 2012 Nepal measles-rubella and polio SIA, we developed an intervention package designed

195 wild poliovirus serotypes causing paralytic polio since the beginning of recorded history.

196 cy collaborations and initiatives beyond the polio sphere.

197 deal" (54% vs 9%), if they do not know that polio spreads through contaminated water (41% vs 14%), o

198 Polio staff and resources are already connected with tho

199 e side, which includes the many well-trained polio staff who have vaccinated children, conducted surv

200 llance, laboratory, and other data to assess polio status in the country (NCC), World Health Organiza

201 2009, the international Stop Transmission of Polio (STOP) program began supporting the Global Polio E

202 In 1999, the Stop Transmission of Polio (STOP) program was developed and initiated by the

203 of oral polio vaccine used during subsequent polio supplemental immunization activities showed a decl

204 to April 2014 to the outcomes of subsequent polio supplemental immunization activities using used pr

205 atic progress was registered in the areas of polio supplementary immunization activities, acute flacc

206 ty-challenged states improved the quality of polio surveillance during the review period.

207 fforts aimed at improving the performance of polio surveillance, vaccination campaigns, increased rou

208 Cases of post-polio syndrome, type 1 diabetes, and chronic cardiomyopa

209 (polioviruses) were associated with the post-polio syndrome, while members of the B species were foun

210 In 2013, the Polio Technical Advisory Group recommended that South Su

211 lasting improvements to public health beyond polio, the Centers for Disease Control and Prevention wi

212 orld Health Assembly resolution to eradicate polio, the government of Nigeria, with support from part

213 and activities beyond those associated with polio, the training they have received to conduct tasks

214 It has brought polio to the brink of eradication.

215 that is considered very high risk (VHR) for polio, to monitor performance of the polio eradication p

216 ing all of the countries at highest risk for polio transmission (Afghanistan, Pakistan, Somalia, and

217 Understanding the determinants of polio transmission and its large-scale epidemiology rema

218 in districts of Afghanistan at high risk for polio transmission and to examine what knowledge, attitu

219 approach highlights the heterogeneity among polio transmission determinants.

220 VCMs) became a key strategy for interrupting polio transmission in the high-risk areas.

221 key covariates of geographical variation in polio transmission patterns by relating country-specific

222 3 months in the settlements at high risk for polio transmission with a RI card seen, from 23% to 56%,

223 he targeting of settlements at high risk for polio transmission with routine immunization (RI) and ot

224 of computer-generated models for predicting polio transmission.

225 (LGAs) of northern Nigeria at high risk for polio transmission.

226 healthy infants aged 6 weeks, not previously polio vaccinated, were allocated after computer-generate

227 We assessed data from polio vaccination activities in OPV-refusing communities

228 k focused initially on generating demand for polio vaccination but later expanded its messaging to pr

229 ess the risk of Sabin 2 transmission after a polio vaccination campaign with a monovalent type 2 oral

230 erational tactics that have led to increased polio vaccination coverage among populations living in d

231 n of several activities to create demand for polio vaccination in persistently poor-performing local

232 With support from Nigeria, the Pakistan polio vaccination program successfully adopted the DDM.

233 pplications including influenza vaccination, polio vaccination, and diabetes are discussed in this re

234 ek-old full-term infants due for their first polio vaccinations, who were healthy on physical examina

235 valent oral polio vaccine with bivalent oral polio vaccine ("the switch").

236 t oral polio vaccine (tOPV) to bivalent oral polio vaccine (bOPV) ("the switch") presented an unprece

237 April, 2016, by bivalent types 1 and 3 oral polio vaccine (bOPV) and one dose of inactivated polio v

238 t oral polio vaccine (tOPV) to bivalent oral polio vaccine (bOPV) has constituted an effort without p

239 -5-component acellular pertussis-inactivated polio vaccine (dT5aP-IPV) was introduced in 2012.

240 ned to receive tOPV (n = 315) or inactivated polio vaccine (IPV) (n = 299) at 39 weeks.

241 synchronized introduction of the inactivated polio vaccine (IPV) and the switch from trivalent oral p

242 da and Indonesia have introduced inactivated polio vaccine (IPV) as part of the Global Polio Eradicat

243 nity through the introduction of inactivated polio vaccine (IPV) in combination with OPV.

244 coordinated efforts to introduce inactivated polio vaccine (IPV) into all countries that did not yet

245 Albania introduced inactivated polio vaccine (IPV) into its immunization system in May

246 Kano State, Nigeria, introduced inactivated polio vaccine (IPV) into its routine immunization (RI) s

247 nly introduce at least 1 dose of Inactivated Polio Vaccine (IPV) into routine immunization schedules

248 troduction of at least 1 dose of inactivated polio vaccine (IPV) into the routine immunization progra

249 PV) introduce at least 1 dose of inactivated polio vaccine (IPV) into their routine immunization sche

250 o vaccine (bOPV) and one dose of inactivated polio vaccine (IPV) where available.

251 using polio assets, introducing inactivated polio vaccine (IPV), and replacing trivalent oral polio

252 and some vaccines, including the inactivated polio vaccine (IPV), must be injected more than once for

253 are key challenges in the use of inactivated polio vaccine (IPV).

254 ation campaign with a monovalent type 2 oral polio vaccine (mOPV2).

255 hat all countries and territories using oral polio vaccine (OPV) "switch" from trivalent OPV (tOPV; t

256 iative program is persistent refusal of oral polio vaccine (OPV) and harassment of vaccination team m

257 ity buy-in, to increase the coverage of oral polio vaccine (OPV) and other routine immunisations, and

258 The phased withdrawal of oral polio vaccine (OPV) associated with the Polio Eradicatio

259 The attenuated oral polio vaccine (OPV) has enabled world-wide vaccination e

260 ion initiative prepares to cease use of oral polio vaccine (OPV) in 2020, there is increasing interes

261 o the switch from trivalent to bivalent oral polio vaccine (OPV) in the 11 countries of the World Hea

262 ended that all 126 countries using only oral polio vaccine (OPV) introduce at least 1 dose of inactiv

263 es (VDPVs), however, remains a risk, as oral polio vaccine (OPV) is still used in many of the region'

264 relies on vaccination of children with oral polio vaccine (OPV) many times a year until the age of 5

265 ll and demands that all countries using Oral Polio Vaccine (OPV) only introduce at least 1 dose of In

266 ization programs of all countries using oral polio vaccine (OPV) only.

267 ude high vaccination coverage with live oral polio vaccine (OPV), surveillance for acute flaccid para

268 Following vaccination with trivalent oral polio vaccine (tOPV) at 6, 10, and 14 weeks, infants wer

269 The global switch from trivalent oral polio vaccine (tOPV) to bivalent oral polio vaccine (bOP

270 ine (IPV) and the switch from trivalent oral polio vaccine (tOPV) to bivalent oral polio vaccine (bOP

271 Trivalent oral polio vaccine (tOPV) was replaced worldwide from April,

272 A total of 2 252 059 inactivated polio vaccine and 2 460 124 oral polio vaccine doses wer

273 simultaneously cease use of the type 2 oral polio vaccine and recommended that all countries and ter

274 rom trivalent (tOPV) to bivalent (bOPV) oral polio vaccine at the national-level and 3 provinces (Bal

275 which calls for a phased withdrawal of oral polio vaccine beginning with the type 2 component, intro

276 c for antigens in rotavirus vaccine and oral polio vaccine containing poliovirus serotypes 1 and 3 we

277 ul in increasing vaccine coverage, including polio vaccine coverage.

278 Introduction of inactivated polio vaccine creates challenges in maintaining the cold

279 inactivated polio vaccine and 2 460 124 oral polio vaccine doses were administered to children aged <

280 ning vaccine and introduction of inactivated polio vaccine in routine immunization to mitigate agains

281 ns (mass immunization campaigns, inactivated polio vaccine introduction, and strengthening of AFP sur

282 nd transportation capacity after inactivated polio vaccine introduction, but temperature fluctuations

283 Today, acceptance of oral polio vaccine is the highest ever.

284 en published and aired, with most portraying polio vaccine positively.

285 of children vaccinated and the doses of oral polio vaccine used during subsequent polio supplemental

286 vaccine (IPV), and replacing trivalent oral polio vaccine with bivalent oral polio vaccine ("the swi

287 ised children (receiving BCG, three doses of polio vaccine, three doses of pentavalent vaccine, and m

288 argest effects were observed for inactivated polio vaccine, where 2-fold higher maternal antibody con

289 uded provision of commodities along with the polio vaccine.

290 ation Initiative to begin withdrawal of oral polio vaccines (OPV), beginning with the type 2 componen

291 t risk will require stopping use of all oral polio vaccines (OPVs) once all types of wild polioviruse

292 gic plan outlines the phased removal of oral polio vaccines (OPVs), starting with type 2 poliovirus-c

293 generate a meaningful policy dialogue about polio vaccines and routine immunization at multiple leve

294 art of the performance of rotavirus and oral polio vaccines in developing countries (PROVIDE) study.

295 wned scholars and Islamic clerics criticized polio vaccines.

296 asing role of the dedicated mobile teams and polio VCMs in strengthening RI.

297 factor VIII heavy chain [FVIII HC]) and 59 (polio VIRAL CAPSID PROTEIN1 [VP1]) rare codons; replacem

298 d for IPV use in campaigns to interrupt wild polio virus and to control type 2 vaccine derived polio

299 virus and to control type 2 vaccine derived polio virus outbreaks, IPV supplies are severely constra

300 t decreases occurred for all vaccines except polio, with the trend of monthly decreases in the number