ライフサイエンスコーパス: poly A

1 If 0.01% poly A were included, the value of kcat/Km increased to

2 chromosomal loci (17%) showed TGF-beta 1RII poly A tract mutation, including 2 cancers and 1 dysplas

3 ranscription can initiate upstream of the 3' poly-A tail during retrotransposon integration.

4 arise given that ribosomal RNA lacks the 3' poly-A tail typically associated with messenger RNA.

5 and eight ncRNAs contained non-templated 3'-poly-A or poly-AG additions.

6 on, we complexed synthetic mRNA containing a poly A tail with PABPs in a stoichiometric manner and st

7 PACS is not dependent on the existence of a poly A tail on an mRNA, it should have application to id

8 a typical polyadenylation signal preceding a poly A tail and the 5' UTR which includes 63-71 bp and t

9 CAI2 is a single-exon gene with a poly A signal located in but independent of the p16/ARF

10 s both a putative start of translation and a poly-A tail.

11 ntly monoallelic and the majority occur at a poly-A tract.

12 NA fragments with zinc finger homology had a poly-A tail and 3 of these fragments contained a putativ

13 245 sequence tags of a poly-A primed cDNA library and 55 sequence tags from a 1

14 The pathogenetic mechanism by which a poly-A tract results in these various human disorders re

15 , their 3' termini lack a polyadenylic acid (poly A) tail and instead contain 2-4 copies of a unique

16 Polyadenylic-polyuridylic acid (poly A:U) is a dsRNA mimetic explored empirically in can

17 Two tandem poly-adenylation (poly A) signals for the GHBP mRNA were found in the 3'-u

18 d there may be a choice of poly-adenylation (poly-A) signal sequence.

19 There are three alternative poly-A addition sites in the long 3' UTR and also six po

20 minal polyadenosine nucleotides (poly A) and poly A binding proteins (PABPs) for optimal expression,

21 d of interlaced networks of both poly A+ and poly A- annotated transcripts and unannotated transcript

22 imited to simple sequences like poly-I:C and poly-A:U.

23 expression profiles from rRNA-depletion and poly-A enrichment are similar.

24 exes consisting of eIF4E, eIF4G, eIF4A1, and poly-A binding protein.

25 se (PNPASE), a 3' --> 5' exoribonuclease and poly-A polymerase, in the mitochondrial intermembrane sp

26 uencing of small RNAs, including miRNAs, and poly-A-enriched mRNAs.

27 LR ignores known SNPs, low quality reads and poly-A/T sequences.

28 sis of DNA sequences around splice sites and poly-A signals is able to explain several observations i

29 ng strongly in vitro to synthetic poly-U and poly-A oligoribonucleotides.

30 hanced the ability of ASL(Lys3)(UUU) to bind poly-A programmed ribosomes.

31 ntly composed of interlaced networks of both poly A+ and poly A- annotated transcripts and unannotate

32 y-T tracts and precisely at their 3' ends by poly-A tracts.

33 ase chain reaction analysis of human cardiac poly A+ mRNA.

34 st some of the mRNA of P. aerophilum carried poly-A tails facilitating the construction of a cDNA lib

35 largely to those obtained from conventional poly-A tail purification methods, indicating both enumer

36 ite scan (PASS) has been developed to detect poly-A sites in the genome.

37 Mitochondrial DNA, poly A RNA, and the cytosolic nucleotide pool were the p

38 al RNA to yield sufficient mRNA using either poly-A selection or depletion of rRNA.

39 scription factor Arx when it has an expanded poly-A tract (Arx(E)), a mutation associated with infant

40 oly-T primers was copying rRNA with extended poly-A 3' ends.

41 o a nuclear region devoid of splicing factor/poly A RNA rich domains.

42 fibroblast growth factor receptor-1 (FGFR1), poly-A-binding protein, cAbl, heterogeneous nuclear ribo

43 somes, as well as increased its affinity for poly-A programmed ribosomes to the level of native Esche

44 Our data demonstrate a novel mechanism for poly-A expansion diseases: the misregulation of a subset

45 s and occur preferentially in homopolymeric (poly A or poly T) genomic stretches.

46 The RET vector uses an improved poly A-trap strategy for the efficient identification of

47 ng system that is not dependent on an intact poly-A tail and showed that it could be used to analyze

48 nd degradation, and that maintaining longer, poly-A-containing arms flanking the miRNA stem-loop mark

49 capture of information distant from the mRNA poly-A tail.

50 ned canine beta(3)-AR cDNA probe and myocyte poly A(+) RNA, we detected a single band about 3.4 kb in

51 Here, we present novel poly A trap vectors that overcome the effect of NMD and

52 pair DNA hairpin attached to a 50-nucleotide poly-A tail (HP-A(50)) is threaded into an alphaHL chann

53 NA on 3'-terminal polyadenosine nucleotides (poly A) and poly A binding proteins (PABPs) for optimal

54 One single peritumoral dose of poly A:U was sufficient to induce IFN-beta, readily visu

55 e/uracil does not affect the fluorescence of poly A nanocapsules.

56 response elicited in a therapeutic model of poly A:U administration.

57 PCR revealed 2.7 x 10(5) molecules per ng of poly A+ RNA.

58 nsposition events and subsequent mutation of poly-A microsatellites within L1.

59 transcriptome data obtained by sequencing of poly-A RNA derived from postmortem dorsolateral prefront

60 Polyanionic polymers such as heparin or poly A substituted for NaCl.

61 fferences in the ORF62 gene and in the ORF64 poly-A region successfully distinguished the Oka vaccine

62 how its proteins act to retrotranspose other poly A elements and the extent of its role in shaping th

63 Moreover, the results show that the PDEbeta poly-A signal has a dominant inhibitory effect over two

64 In each study cohort, we performed poly-A RNA-sequencing in baseline samples from 25 respon

65 These polyadenylation (poly A) trap vectors employ a splice donor to capture an

66 Polyalanine (poly-A) tracts exist in 494 annotated proteins; to date,

67 complexes (RNCs) with different polyalanine (poly-A) inserts or signal peptides from membrane/secreto

68 GF-beta 1RII coding region polydeoxyadenine (poly A) microsatellite tract was polymerase chain reacti

69 erence RNA standards to test four protocols (poly-A-selected, ribo-depleted, size-selected and degrad

70 3 more at the amino terminus, and a putative poly A tail.

71 cating that TLR3 is required for recognizing poly A:U.

72 amplified from barley (Hordeum vulgare) root poly A+ RNA and used as probes to screen a barley root c

73 different library preparation kits (standard poly-A versus total RNA with Ribozero depletion) and ana

74 Mutational inactivation of the poly A microsatellite tract within TGF-beta 1RII occurs

75 olorectal cancer patients is mutation of the poly A tract of the transforming growth factor-beta rece

76 rat and mouse GHR/GP gene suggests that the poly A signals and GT repeat may be involved in the regu

77 ing an epitope-tagged protein that binds the poly-A tail of mRNAs (FLAG::PAB-1) from an intestine-spe

78 single polyadenylation site 229 nt from the poly-A tail.

79 UAG stop codon immediately downstream of the poly-A tract.

80 A molecules is accomplished by targeting the poly-A tail with an oligo-dT20 modified gold nanoparticl

81 mmunoblotting, we were able to show that the poly-A inserts embedded in the passage tunnel can form a

82 main (ASL(Lys3)(UUU)), are unable to bind to poly-A programmed ribosomes.

83 We thus expect that a translated poly-A tail, encoding for positively charged lysines reg

84 ter trimming, amplification primer trimming, poly-A tail trimming, vector screening and low quality r

85 available methods of mRNA enrichment (TruSeq poly-A enrichment and RiboMinus rRNA depletion).

86 both these changes and increases in tubulin poly A+ mRNA and protein coexist indefinitely after a ne

87 tumor-specific immune response elicited upon poly A:U administration.

88 t mammalian Larp1 is found in a complex with poly A binding protein and eukaryote initiation factor 4

89 d with probes to TIMP-1 to -4 and GAPDH with poly A+ mRNA from ventricular tissues of patients with i

90 s oligomer was similar to that observed with poly A or high salt concentration when the molar ratio o

91 ARP1) is a conserved RBP that interacts with poly-A-binding protein and is known to regulate 5'-termi