ライフサイエンスコーパス: poly(A) binding protein

1 d intact poly(A) tails and were bound by the poly(A) binding protein.

2 as the 47-kD protein was shown to be RB47, a poly(A) binding protein.

3 n factor I, purified poly(A) polymerase, and poly(A) binding protein.

4 oocyte masking protein FRGY2/mRNP3+4, and a poly(A) binding protein.

5 70, translation initiation factor eIF4G, and poly(A) binding protein.

6 well as cause nuclear relocalization of the poly(A) binding protein.

7 This process requires the presence of a poly(A)-binding protein.

8 ith eIF4A, an RNA unwinding factor, and with poly(A)-binding protein.

9 ly cytoplasmic polyadenylation, but also the poly(A)-binding protein.

10 IRES activity was enhanced moderately by the poly(A)-binding protein.

11 t with eIF4A, eIF4B, eIF4E isoforms, and the poly(A)-binding protein.

12 hich is a pattern consistent with binding of poly(A)-binding protein.

13 and disrupted the association of eIF4G with poly(A)-binding protein.

14 the 5' end of mRNA preactivated by eIF4F and poly(A)-binding protein.

15 fp36 directly interacts with the cytoplasmic poly(A)-binding protein.

16 al repression via modulating the cytoplasmic poly(A)-binding protein.

17 ith RNA, poly(A) polymerase, and the nuclear poly(A)-binding protein.

18 ucleotides consistent with phased binding of poly(A) binding proteins.

19 did not affect its ability to interact with poly(A) binding proteins.

20 e aspects of mRNA metabolism consists of the poly(A) binding proteins.

21 aracterized RNA recognition motif-containing poly(A) binding proteins.

22 immunity induction through interaction with poly(A)-binding proteins.

23 ing proteins, including ELAV/Hu, eIF-4E, and poly(A)-binding proteins.

24 and how the poly(A) tail and the associated poly(A) binding protein 1 (Pab1p) may affect this proces

25 o which it binds, which includes cytoplasmic poly(A) binding protein 1 (PABP1).

26 eracts with HPV16 E6, as well as cytoplasmic poly(A) binding proteins 1 and 4 (PABPC1 and PABPC4).

27 Interestingly, SUP-26 associates with poly(A)-binding protein 1 (PAB-1) in vivo and may repres

28 ibonucleoprotein particles (mRNPs) via eIF4F-poly(A)-binding protein 1 (Pab1) association, suggesting

29 ments, are not co-labeled with the SG marker poly(A)-binding protein 1 (PABP-1), whereas inclusions i

30 Here we show that poly(A)-binding protein 1 (PABP1) binds preferentially t

31 ve studied the intracellular localization of poly(A)-binding protein 1 (PABP1) by indirect immunofluo

32 erived from the well-defined CARM1 substrate poly(A)-binding protein 1 (PABP1) were covalently linked

33 NAs encoding human ribosomal protein, RPS17, poly(A)-binding protein 1 (PABP1), and the elongation fa

34 trate that regulated expression of cytosolic poly(A)-binding protein 1 (PABPC1) modulates protein syn

35 The nuclear poly(A)-binding protein 1 (PABPN1) is a ubiquitously exp

36 within the N-terminal domain of the nuclear poly(A)-binding protein 1 (PABPN1) to maximally 17 alani

37 RSK2 colocalizes in granules with TIA-1 and poly(A)-binding protein 1, and the sequestration of RSK2

38 ulin and at least two mRNA-binding proteins, polyA-binding protein 1 and a 130 kDa polyA-mRNA binding

39 ine triplet repeat expansion in the gene for poly(A) binding protein 2 (PABP2) and is found in isolat

40 odes for a ubiquitous nuclear protein called poly(A) binding protein 2 (PABP2).

41 nucleotide repeat expansion in exon 1 of the poly(A) binding protein 2 gene (PABP2), in which (GCG)(6

42 Poly(A) binding protein, along with PCBP 1 and 2, also c

43 onal ortholog, CNBP also associates with the poly(A) binding protein and accumulates in stress granul

44 o proteins involved in mRNA recognition, the poly(A) binding protein and the translation initiation f

45 Poly(A)-binding protein and eIF4B mainly affect the eIF4

46 ing protein eIF4E, eIF4E kinase Mnk1, eIF4A, poly(A)-binding protein and eIF4G.

47 of factors eIF4E, eIF4A, eIF4E kinase Mnk1, poly(A)-binding protein, and adaptor protein eIF4G.

48 th poly(A) tails, inhibit the association of poly(A)-binding protein, and confer increased stability

49 teractions of eIF4G with eIF4E, eIF4A, eIF3, poly(A)-binding protein, and Mnk1/2 have been mapped to

50 port receptor (transportin), the cytoplasmic poly(A)-binding protein, and mRNA.

51 tion, i.e., eukaryotic initiation factor 4G, poly(A)-binding protein, and poly(A) tail.

52 2, forms a complex with PAB-1, a cytoplasmic polyA-binding protein, and that ATX-2 is required for de

53 in of the large ribosomal subunit), pab-1 [a poly(A)-binding protein], and glp-3/eft-3 (an elongation

54 Poly(A) binding proteins are a family of eukaryotic, cyt

55 e canonical RNA recognition motif-containing poly(A) binding proteins as the sole family of poly(A)-s

56 of Psk1, which phosphorylates and activates poly(A)- binding protein binding protein 1 (Pbp1), which

57 cloverleaf RNA structure interacts with the poly(A) binding protein bound to the 3' poly(A) tail, th

58 ate that was dependent on a poly(A) tail and poly(A)-binding protein, but was independent of eIF4F fu

59 d formation between RNA binding domains in a poly(A)-binding protein can be used to regulate the abil

60 promotes deadenylation, whereas the putative poly(A) binding protein CG4612 promotes oligomeric Orb2-

61 ich may be a consequence of the poly(A) tail-poly(A)-binding protein complex functioning as a steric

62 d to regulate translation in organisms whose poly(A)-binding proteins contain these critical cysteine

63 dation protein, DEAD box helicase 5, and the poly(A) binding protein cytoplasmic 1.

64 D-translation and termination codon-proximal poly(A) binding protein-depend on the ATPase activity of

65 il represses decapping of RNAs in vitro in a poly(A)-binding protein-dependent fashion.

66 The phosphorylation of eIF-2beta (p38) or poly(A)-binding protein did not change either during ger

67 ribosome entry site interaction with eIF4F, poly(A)-binding protein did not increase eIF4F binding.

68 ific target of Hsp27, as eIF4E, eIF4A, Mnk1, poly(A)-binding protein, eIF4B, and eIF3 were not bound

69 An isoform containing the binding site for poly(A)-binding protein, eIF4G-1e(DM), was more active i

70 The addition of eIF4B and poly(A)-binding protein enhanced the association rate of

71 We recently identified an embryonic poly(A)-binding protein (ePAB) in Xenopus.

72 or Azoospermia-like (DAZL) and the embryonic poly(A)-binding protein (ePAB).

73 ian and Xenopus PABP1 and is the predominant poly(A)-binding protein expressed in the stage VI oocyte

74 drial targeting of a member of the cytosolic poly(A) binding protein family, PABPC5, and of the RNA/D

75 d identified this protein as a member of the poly(A) binding protein family.

76 RB47 is a member of the poly(A)-binding protein family, and binds with high affi

77 ration of eIF4F or eIFiso4F and required the poly(A)-binding protein for optimal function.

78 The poly(A)-binding protein from Saccharomyces cerevisiae la

79 en reported that the expression of the yeast poly(A) binding protein gene (PAB1) in plants leads to a

80 E-binding protein called ePAB (for embryonic poly(A)-binding protein) has been purified from this ext

81 in this category, overexpression of Acinus1, Poly(a) binding protein, HNRPA2B1, Bop1, and Gemin5 was

82 mains to be elucidated, the highly conserved poly(A) binding protein I (PABP) mediates poly(A)-depend

83 protein) via its effector domain targets the poly(A)-binding protein II (PABII) of the cellular 3'-en

84 eIF-4B, eIF-4F, eIF-iso4F, and eIF-2 and the poly(A)-binding protein in the seed, during germination,

85 RP with stress granules and colocalizes with polyA binding protein in a variant-dependent manner.

86 ; PABP, a poly(A) binding protein; PAIP-1, a poly(A) binding protein interacting protein; hnRNP D, an

87 inhibitors is mediated, at least in part, by poly(A)-binding protein-interacting protein 2 (PAIP2), w

88 ues in RNA binding domains 2 and 3, and this poly(A)-binding protein lacks the ability to be regulate

89 he gene encoding the Leishmania homologue of poly(A)-binding protein (Lm PAB1), as an approach to the

90 These data also suggest that poly(A) binding proteins may play a wider role in transl

91 ain with eukaryotic initiation factor 4A and poly(A) binding protein mediate repression, indicating t

92 ) specific 3' exoribonuclease, mtPARN, and a poly(A)binding protein, mtPABP1.

93 s the cap-binding complex [CBC]) at the cap, poly(A)-binding protein N1 (PABPN1) and PABPC1 at the po

94 -expansion mutation in the gene encoding for poly(A) binding protein nuclear 1 (expPABPN1).

95 sease caused by polyalanine expansion in the poly(A) binding protein nuclear 1 (PABPN1).

96 Here, we report poly(A)-binding protein nuclear 1 (PABPN1) as a novel TD

97 Alanine expansion mutations in poly(A)-binding protein nuclear 1 (PABPN1) cause muscle

98 -13) expansions within the first exon of the poly(A)-binding protein nuclear 1 gene (PABPN1), leading

99 Protein levels of the APA regulator, poly(A)-binding protein nuclear-1 were substantially dow

100 olyalanine tract within the coding region of polyA binding protein nuclear 1 (PABPN1).

101 an N-terminal expanded polyalanine tract in polyA-binding protein nuclear 1 (PABPN1).

102 Poly(A)-binding protein (PAB) binds to the poly(A) tail

103 Poly(A)-binding protein (PAB) is an evolutionarily conse

104 he translation apparatus, and also binds the poly(A) binding protein Pab1.

105 the proline-rich region and RRM1 domains of poly(A) binding protein (PAB1) as necessary for CCR4 dea

106 s internal initiation via recruitment of the poly(A) binding protein (Pab1) to the 5' untranslated re

107 We show that poly(A)-binding protein (Pab1 in yeast), a defining mark

108 lly identified as a suppressor mutation of a poly(A)-binding protein (PAB1) gene deletion, stabilizes

109 shown, in turn, to necessitate a functional poly(A)-binding protein (PAB1) in which removal of the R

110 In this study, we identify the poly(A)-binding protein, Pab1, and the poly(A) nuclease,

111 ted by the cap-binding complex eIF4F and the poly(A)-binding protein, Pab1.

112 found to coimmunoprecipitate with the yeast poly(A) binding protein Pab1p.

113 We demonstrate that the poly(A)-binding protein Pab1p is required for PUF-mediat

114 h both the cap-binding protein eIF4E and the poly(A)-binding protein Pab1p.

115 ase is inhibited in vitro by addition of the poly(A) binding protein (Pab1p), suggesting that dissoci

116 x, and the translation/mRNA stability factor poly(A) binding protein (Pab1p).

117 tail interacts with a conserved polypeptide, poly(A) binding protein (Pab1p).

118 that the yeast protein Pbp1p associates with poly(A)-binding protein (Pab1p) and controls the extent

119 otic mRNA 3' poly(A) tail and its associated poly(A)-binding protein (Pab1p) are important regulators

120 The yeast poly(A)-binding protein (Pab1p) contains four RNA recogn

121 associated with this 3'-end structure is the poly(A)-binding protein (Pab1p) encoded by the PAB1 gene

122 Tethered poly(A)-binding protein (Pab1p), used as a mimic of a no

123 d Pan3p subunits, as well as the presence of poly(A)-binding protein (Pab1p).

124 accharomyces cerevisiae is stimulated by the poly(A)-binding protein (Pab1p).

125 d two protein components other than Scp160p: poly(A) binding protein, Pab1p, and Bfr1p.

126 suggested to be due to an interaction of the poly(A) binding protein, Pab1p, with eukaryotic translat

127 tic backgrounds, these granules also contain poly(A)-binding protein, Pab1p, and additional mRNA expo

128 be recapitulated in vitro by the cytoplasmic poly(A)-binding protein PABP through a direct and specif

129 Recently, the poly(A) binding protein (PABP) and cap-binding protein,

130 ich region is removed, we decided to examine poly(A) binding protein (PABP) as a candidate member of

131 The ubiquitous and abundant cytoplasmic poly(A) binding protein (PABP) is a highly conserved mul

132 Poly(A) binding protein (PABP) is an essential, well-con

133 and cattle, utilize a functional homolog of poly(A) binding protein (PABP) known as nonstructural pr

134 d cells stimulates synthesis of the cellular poly(A) binding protein (PABP), significantly increasing

135 ewly elongated poly(A) tail becomes bound by poly(A) binding protein (PABP), which in turn binds eIF4

136 tails of eukaryotic mRNAs are complexed with poly(A) binding protein (PABP).

137 IF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).

138 that can bind poly(A) RNA and interact with poly(A) binding protein (PABP).

139 unit to an mRNA and for interacting with the poly(A) binding protein (PABP).

140 e replication complexes, as well as cellular poly(A) binding protein (PABP).

141 multiple initiation factors, mRNA, rRNA, and poly(A) binding protein (PABP).

142 Viral 3C protease (3Cpro) cleaves poly(A)-binding protein (PABP) and removes the C-termina

143 complex, whose binding domains for eIF4E and poly(A)-binding protein (PABP) are thought to enhance fo

144 IF-4F and eIF-iso4F) and eIF-4B, bind to the poly(A)-binding protein (PABP) both in the presence and

145 of the poly(A) tail was mediated through the poly(A)-binding protein (PABP) bound to the poly(A) tail

146 Cleavage of poly(A)-binding protein (PABP) by 3C(pro) has been shown

147 Further equilibrium studies showed that poly(A)-binding protein (PABP) enhanced the cap binding

148 their binding to the transcript excludes the poly(A)-binding protein (PABP) from the complex.

149 The cocrystal structure of human poly(A)-binding protein (PABP) has been determined at 2.

150 cleavage of eIF4GI, cleavage of eIF4GII and poly(A)-binding protein (PABP) has been recently propose

151 from norovirus and FCV were found to cleave poly(A)-binding protein (PABP) in the absence of other v

152 Recent studies demonstrated that wheat germ poly(A)-binding protein (PABP) interacted with translati

153 The poly(A)-binding protein (PABP) interacts with the cap-as

154 The poly(A)-binding protein (PABP) interacts with the eukary

155 Poly(A)-binding protein (PABP) is a major component of t

156 Eukaryotic poly(A)-binding protein (PABP) is a ubiquitous, essentia

157 A FLAG-tagged poly(A)-binding protein (PABP) is expressed in a specifi

158 des, which is consistent with the binding of poly(A)-binding protein (PABP) monomers.

159 Co-injection of poly(A)-binding protein (PABP) mRNA increased the functi

160 that the highly conserved 70-kDa cytoplasmic poly(A)-binding protein (PABP) participates directly in

161 The poly(A)-binding protein (PABP) recognizes the 3' mRNA po

162 ocarditis virus (EMCV) infection on the host poly(A)-binding protein (PABP) remains unknown.

163 genes, fabM, which is predicted to encode a poly(A)-binding protein (PABP) that is constitutively ex

164 nteractions between the poly(A) tail and the poly(A)-binding protein (PABP) to achieve maximal IRES-m

165 mini are brought together by interactions of poly(A)-binding protein (PABP) with both the poly(A) tai

166 The poly(A)-binding protein (PABP), a key component of diffe

167 molog, ATX2, assemble with polyribosomes and poly(A)-binding protein (PABP), a key regulator of mRNA

168 The poly(A)-binding protein (PABP), a protein that contains

169 ts interactions with eIF4A, eIF4G, eIF3, the poly(A)-binding protein (PABP), and RNA.

170 s a complex with initiation factor eIF4G and poly(A)-binding protein (PABP), and strongly and selecti

171 YF associates with a 5'-cap-binding complex, poly(A)-binding protein (PABP), as well as per and tim t

172 ter correction for mRNA load: genes encoding poly(A)-binding protein (PABP), heat-shock proteins hsp7

173 NA stability through an association with the poly(A)-binding protein (PABP).

174 tified the 73-kDa protein as the cytoplasmic poly(A)-binding protein (PABP).

175 ed 3' end translational stimulatory protein, poly(A)-binding protein (PABP).

176 controlled by the 3' poly(A) tail (PAT) and poly(A)-binding protein (PABP).

177 ovides evidence that this is mediated by the poly(A)-binding protein (PABP).

178 genetically with, the translation regulator poly(A)-binding protein (PABP).

179 eIF4GI, poly(A)-binding protein (PABP)1, eIF3, eIF4AI, and eIF2a

180 icoid, and with genes encoding eIF4E, Larp1, polyA binding protein (PABP), and Ago2.

181 We show that Cup and polyA-binding protein (PABP) interact physically with Sq

182 cts with a central stress granule component, polyA-binding protein (PABP).

183 e methylation of two known CARM1 substrates, poly(A)-binding protein (PABP1) and the transcriptional

184 However, the cytoplasmic somatic cell poly(A)-binding protein (PABP1) is not expressed until l

185 tes poly(A)RNA transport via deacetylating a poly(A)-binding protein, PABP1.

186 ncoding the testis-specific isoform of mouse poly(A) binding protein (Pabp2) has been isolated and se

187 The mammalian nuclear poly(A) binding protein, PABP2, controls the length of t

188 demonstrate that accumulation of cytoplasmic poly(A) binding protein (PABPC) in the nucleus, which ca

189 Recent studies have found the cytoplasmic poly(A) binding protein (PABPC) to have opposing effects

190 proteins hrp36 and hrp38 and the cytoplasmic poly(A)-binding protein PABPC1 as novel functional compo

191 ndently binds to poly(A) RNA, RACK1, and the poly(A)-binding protein (PABPC1).

192 clease complex CCR4-CAF1 and the cytoplasmic poly(A)-binding protein, PABPC1.

193 s of NFX1-123, including several cytoplasmic poly(A) binding proteins (PABPCs) that interacted with N

194 RT expression through binding to cytoplasmic poly(A) binding proteins (PABPCs).

195 e cases, splicing is promoted by the nuclear poly(A) binding protein, PABPN1, and poly(A) polymerase

196 ression of the PAB5 gene encoding one of the poly(A) binding proteins (PABPs) in Arabidopsis is restr

197 Poly(A) binding proteins (PABPs) specifically bind the p

198 Poly(A)-binding proteins (PABPs) are multifunctional pro

199 Cytoplasmic poly(A)-binding proteins (PABPs) link mRNA 3' termini to

200 Poly(A)-binding proteins (PABPs) play crucial roles in m

201 We show that DAZL proteins interact with poly(A)-binding proteins (PABPs), which are critical for

202 cally associated with A3G and A3F, including poly(A)-binding proteins (PABPs), YB-1, Ro-La, RNA helic

203 pacted by its 3' poly(A) tail and associated poly(A)-binding proteins (PABPs).

204 tely related to the functions of the cognate poly(A)-binding proteins (PABPs).

205 the poly(A) tail of mRNA transcripts, called poly(A)-binding proteins (Pabs), play critical roles in

206 , a purine-rich RNA binding protein; PABP, a poly(A) binding protein; PAIP-1, a poly(A) binding prote

207 amydomonas reinhardtii chloroplast-localized poly(A)-binding protein RB47 is predicted to contain a n

208 Binding of the chloroplast poly(A)-binding protein, RB47, to the psbA mRNA is regul

209 Here, we identify Nab2p as a nuclear poly(A)-binding protein required for both poly(A) tail l

210 ith ICP27 most likely when bound to cap- and poly(A)-binding proteins, respectively.

211 These data argue that ePAB is the poly(A)-binding protein responsible for stabilization of

212 serine residue inhibits its interaction with poly(A)-binding protein, resulting in reduced translatio

213 tibodies against mrnp 41 and the cytoplasmic poly(A) binding protein showed colocalization to the cyt

214 -function mutations in SIS1 as well as PAB1 (poly(A)-binding protein), suggesting a functional intera

215 mouse Pabp2 retroposon encodes an isoform of poly(A) binding protein that is expressed in meiotic and

216 component of the 30 S ribosomal subunit, are poly(A)-binding proteins that interact functionally and

217 Poly(A)-binding protein, the most abundant eukaryotic mR

218 in physically interacted with polyadenylate [poly(A)]-binding protein through it RGG motifs.

219 Poly(A)-binding protein thus acts as a physiological str

220 Here, we show that ePAB, embryonic poly(A)-binding protein, transiently associates with the

221 We identified that both poly(A) binding proteins were associated with the L1 rib

222 Two binding sites for the poly(A)-binding protein were mapped to a region within e

223 element of the cap-binding complex, and the poly(A)-binding protein, which binds to the complex.

224 enylation and the consequent dissociation of poly(A) binding protein will result in PTC-like terminat

225 y(A) tail is mediated through interaction of poly(A)-binding protein with eukaryotic initiation facto

226 fense responses by accumulation of the yeast poly(A) binding protein would turn off the expression of

227 BP2-TRP) of Xenopus laevis embryonic type II poly(A)-binding protein (XlePABP2).