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1 ctivated caspase-7 and caspase-9 and induced polyadenosine-5'-diphosphate-ribose polymerase (PARP) cl
2 ex, bound to the 5' end of the mRNA, and the polyadenosine binding protein, bound to the 3'-terminal
4 red by the dependence of mRNA on 3'-terminal polyadenosine nucleotides (poly A) and poly A binding pr
7 on, and the polyadenylation step that adds a polyadenosine [poly(A)] tract to the newly generated 3'
8 d the parnafungins, which inhibit the enzyme polyadenosine polymerase (PAP), a key component of the m
11 mechanism, causing formation and addition of polyadenosine-ribose (PAR) to acceptor proteins includin
12 3-5 of Chaetomium thermophilum Nab2 bound to polyadenosine RNA and establish the structural basis for
13 nc finger protein that binds specifically to polyadenosine RNA and is thus postulated to modulate pos
15 ated a role for the evolutionarily conserved polyadenosine RNA binding protein, Nab2, in mRNA maturat
19 se coupled processes, we defined the mode of polyadenosine RNA recognition for the conserved Saccharo
20 tant Nab2 proteins with decreased binding to polyadenosine RNA show growth defects as well as defects
22 the ZC3H14 ortholog dNab2, which also binds polyadenosine RNA, reveals that dNab2 is essential for d
23 main, suggesting that they could all bind to polyadenosine RNA, they differ in other functionally imp
24 a gene that encodes a ubiquitously expressed polyadenosine RNA-binding protein, ZC3H14 (Zinc finger C
27 pausing events were strongly associated with polyadenosine sequences and to a lesser degree diadenosi
31 nding proteins (PABPs) specifically bind the polyadenosine tail of mRNA and have been shown to be imp
32 polymerase (PAP) catalyzes the addition of a polyadenosine tail to almost all eukaryotic messenger RN
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