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1 , are capped but, unlike host mRNAs, are not polyadenylated.
2 y cleavage by RNase P and are capped but not polyadenylated.
3 ense transcripts that were not capped and/or polyadenylated.
4 transcribed by RNA polymerase II but are not polyadenylated.
5 s are the only eukaryotic mRNAs that are not polyadenylated.
6 NAs are the only metazoan mRNAs that are not polyadenylated.
7 gation complexes are efficiently cleaved and polyadenylated.
8 lymerase I or III and are not believed to be polyadenylated.
9 3'UTR is unusually long and is alternatively polyadenylated.
10 verified that bound mRNA remained intact and polyadenylated.
11 ncreases in the number of mRNA isoforms with polyadenylated 3' ends that map to 5'-untranslated regio
13 ments for two yeast snoRNA genes also direct polyadenylated 3'-end formation in the context of an mRN
14 all si/miRNA-sized fragments, (ii) uncapped, polyadenylated 3-prime fragments that encode the conserv
18 ut the day, some newly synthesized rRNAs are polyadenylated and degraded in the nucleus in a robustly
20 es and an H3 gene that encode mRNAs that are polyadenylated and expressed at 5- to 10-fold lower leve
21 anscripts produced tend to be unspliced, non-polyadenylated and expressed at levels 10 to 100-fold lo
22 from the last (most telomeric) D4Z4 unit is polyadenylated and has two introns in its 3-prime untran
23 replication-dependent histone mRNAs are not polyadenylated and instead end in a conserved stem loop
25 ess, we examined >1 billion RNA-seq reads of polyadenylated and nonpolyadenylated RNA from differenti
26 mplex is involved in the 3' end formation of polyadenylated and nonpolyadenylated RNA polymerase II t
28 been implicated in the transcription of both polyadenylated and nonpolyadenylated RNAs, Paf1C had not
29 ome an interleaved network of both annotated polyadenylated and nonpolyadenylated transcripts, includ
30 ep, multiple-stage reaction, where RNAs were polyadenylated and reverse-transcribed at the same time.
32 cific RNA-seq to deeply profile lncRNAs from polyadenylated and total RNA obtained from human neocort
33 The m169 transcript is cytoplasmic, capped, polyadenylated, and interacts with miRNA-27 through seed
36 howed that pc7 transcripts are expressed and polyadenylated, and that the PC7 precursor protein under
37 , to control the expression of alternatively polyadenylated antisense RNAs at the locus encoding the
39 es for PAP I in wild-type cells, are rapidly polyadenylated as PAP I levels increase, leading to dram
40 t of our knowledge, this description of both polyadenylated as well as nonpolyadenylated lncRNA trans
44 ncode the viral nonstructural proteins, were polyadenylated at a high efficiency at a polyadenylation
45 d from the upstream P7 and P19 promoters are polyadenylated at a site in the central intron ((pA)p);
46 s, primarily extended through (pA)p and were polyadenylated at a site, (pA)d, located at the right en
47 ng patterns are used, and each type is found polyadenylated at either the 3' end of the genome (the d
48 stranded positive-sense RNA molecule that is polyadenylated at its 3' end and covalently linked to a
50 that upstream antisense RNAs are cleaved and polyadenylated at poly(A) sites (PASs) shortly after ini
51 gonucleotide prevented B19V mRNA transcripts polyadenylated at the (pA)d site during B19V infection o
52 a sufficient number of B19V mRNA transcripts polyadenylated at the distal polyadenylation site ((pA)d
53 s generated by the proximal P41 promoter are polyadenylated at the distal polyadenylation site at the
54 d version of the full-length GP mRNA that is polyadenylated at the editing site and thus lacks a stop
57 rst report to show that the highly expressed polyadenylated BamHI A rightward transcripts (BART) vira
58 ential regulatory properties of the spliced, polyadenylated BART RNAs, a full-length cDNA clone of on
61 nt ATX2 protein that does not associate with polyadenylate-binding protein (PABP) suppressed behavior
62 ells, we found diminished association of the polyadenylate-binding protein (PABP) with the cap-bindin
66 e methylation of histone (H3) or nonhistone (polyadenylate-binding protein 1, PABP1) substrates induc
67 search for proteins interacting with hEndoV, polyadenylate-binding protein C1 (PABPC1) was identified
69 buildup of translational repressors, such as polyadenylate-binding protein interacting protein 2 (Pai
70 short abnormal polyalanine expansion in the polyadenylate-binding protein nuclear-1 (PABPN1) protein
73 istone mRNAs are the only mRNAs that are not polyadenylated but instead end in a stem-loop which has
75 sequences present in BIC RNA, a spliced and polyadenylated but non-protein-coding RNA that accumulat
76 recently that sno-lncRNAs are not capped or polyadenylated but rather are terminated on each end by
77 ammalian mRNAs because they are not normally polyadenylated but, rather, are cleaved following a 3' s
78 ackaged into complete ribosomal subunits are polyadenylated by the poly(A) polymerase PAPD5 and degra
79 hat the nuclear-restricted pre-ribosomes are polyadenylated by TRAMP and degraded by the exosome.
82 NA metabolism events, we identify non-coding polyadenylated cis natural antisense transcripts (cis-NA
84 in the 3' long terminal repeat (LTR) was not polyadenylated detectably in vitro; however, if the tran
87 protein isoform produced from the proximally polyadenylated DOG1 mRNA is a key player in the establis
88 ut the mechanisms by which these genomes are polyadenylated during viral replication remain obscure.
91 As contain no introns, and the mRNAs are not polyadenylated, ending instead in a conserved stem-loop
92 only eukaryotic cellular mRNAs that are not polyadenylated, ending instead in a conserved stem-loop.
97 svirus produces a 1077 nucleotide noncoding, polyadenylated, exclusively nuclear RNA called PAN that
98 f 44 microRNAs (miRNAs), and the spliced and polyadenylated exons form nuclear non-protein-coding RNA
103 essing of the major pri-miR171a, spliced and polyadenylated forms of which accumulate in plants homoz
104 und that the drug causes the accumulation of polyadenylated fragments of the 27S rRNA precursor and t
105 ression of pre-mRNAs prematurely cleaved and polyadenylated from cryptic polyadenylation signals (PAS
106 was established for quantitative analysis of polyadenylated full-length (fl) and truncated (tr) HBV R
111 lular mRNA, translation of the uncapped, non-polyadenylated hepatitis C virus (HCV) genome occurs ind
112 results in accumulation of small amounts of polyadenylated histone mRNA and nascent read-through tra
114 f 7SK led to an enhanced ratio of cleaved to polyadenylated histone transcripts, an effect dependent
119 ranscripts encoding the capsid proteins were polyadenylated in the right-hand terminal palindrome.
121 A-less promoters and are neither spliced nor polyadenylated; instead, 3' processing is directed by a
123 ong the intervening DNA, synthesizing short, polyadenylated, intergenic RNAs to ultimately loop with
125 e Expression) sequencing to globally resolve polyadenylated isoform structures in replicating Epstein
127 ockd (lncRNA downstream of Cdkn1b), a 434-nt polyadenylated lncRNA originating 4 kb 3' to the Cdkn1b
128 Analysis of the mouse erythro-megakaryocytic polyadenylated lncRNA transcriptome indicates that ~75%
129 We used RNA sequencing to identify 1109 polyadenylated lncRNAs expressed in erythroblasts, megak
131 ion signal with sequences derived from a non-polyadenylated long non-coding RNA (MALAT1), which can f
136 xon 2 resulting in the production of a small polyadenylated mRNA (HTTexon1) that encodes the highly p
138 We demonstrate that hos1 mutants accumulate polyadenylated mRNA in the nucleus and that the circadia
139 adaptors that flag alternatively spliced and polyadenylated mRNA isoforms as cargo ready for the cyto
142 he oligo(dT)-primed reverse transcription of polyadenylated mRNA templates used to generate EST cDNA
143 its exact complement (the antigenome), and a polyadenylated mRNA that acts as a template for the smal
145 nt splicing of exon 1 HTT results in a short polyadenylated mRNA that is translated into an exon 1 HT
146 ated in vitro and also when m(7)G-capped and polyadenylated mRNA was transiently transfected into 293
149 nscription factors, and enzymes that cap and polyadenylate mRNAs within the cytoplasm of infected ani
151 mplexes-one specifically crafted to generate polyadenylated mRNAs and the other to generate nonpolyad
152 requires shortened/no poly(A)-tail targets; polyadenylated mRNAs are partially activated upon PAIP2
155 d of the genome followed by 5'-capped and 3'-polyadenylated mRNAs from internal genes by a stop-start
157 of this system, including the prevalence of polyadenylated mRNAs in the bacterium, are still poorly
158 Transcription termination for genes encoding polyadenylated mRNAs requires a functional poly(A) signa
159 erminal portion of DUX4 and (iii) capped and polyadenylated mRNAs that contain the double-homeobox do
161 s the genomic RNA to produce five capped and polyadenylated mRNAs with the 5'-terminal structure 7mGp
164 ssed in terminally differentiated tissues as polyadenylated mRNAs, likely serving as replacement hist
165 eta-lactamase family generate the 3' ends of polyadenylated mRNAs, nonpolyadenylated histone mRNAs, a
167 er half of human genes produce alternatively polyadenylated mRNAs, suggesting that regulated polyaden
173 quently yielded an accumulation of shortened polyadenylated mtRNA species and impaired mitochondrial
175 PAP1, which is located in the nucleus, is to polyadenylate non-coding RNAs, which undergo trans-splic
177 s, 19.4, 43.7, and 36.9% were observed to be polyadenylated, nonpolyadenylated, and bimorphic, respec
179 osi's sarcoma-associated herpes virus (KSHV) polyadenylated nuclear (PAN) RNA facilitates lytic infec
181 ith a 9-nucleotide (nt) core element of KSHV polyadenylated nuclear (PAN) RNA, a viral long noncoding
182 es a highly abundant, nuclear noncoding RNA, polyadenylated nuclear (PAN) RNA, which contains an elem
187 , ORF59, K8alpha, K8.1, or a higher level of polyadenylated nuclear RNA after butyrate induction and
188 the Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA contains a 79-nt cis-acting e
189 monomeric red fluorescent protein 1 (mRFP1), polyadenylated nuclear RNA promoter (pPAN)-enhanced gree
190 the Kaposi's sarcoma-associated herpes virus polyadenylated nuclear RNA) are not efficiently processe
191 paired in activating direct targets, such as polyadenylated nuclear RNA, and indirect targets, such a
192 ranscriptome showed that several viral RNAs (polyadenylated nuclear RNA, open reading frame 58 [ORF58
193 which we named lncRNA-CMPK2, was a spliced, polyadenylated nuclear transcript that was induced by IF
194 bearing two C-G*C(H+) interrupts), and (3) a polyadenylated nuclear-nuclear retention element complex
195 130 kb upstream of miR-21, are spliced, and polyadenylated only a few hundred base pairs upstream of
198 ts and reconstituted exosomes using AU-rich, polyadenylated (poly[A]), generic, and structured RNA su
200 tingly, nucleolin physically interacted with polyadenylate [poly(A)]-binding protein through it RGG m
201 in which we identify 72 factors required for polyadenylated [poly-(A(+))] mRNA export from the nucleu
202 U-rich internal loop hybridizes with the 3'-polyadenylate (polyA) tail to sequester it from exonucle
203 idopsis continues to suggest the presence of polyadenylated (polyA) transcripts originating from pres
207 eviously undescribed prematurely cleaved and polyadenylated pre-mRNAs, some of which contain novel OR
210 as mRNAs, pre-mRNAs, or those RNAs that are polyadenylated prior to their degradation in the nucleus
211 found that human NLRP3 can be alternatively polyadenylated, producing a short 3'-UTR isoform that ex
212 rt that the yeast RPB2 gene is alternatively polyadenylated, producing two mRNAs with different lengt
213 d >28,000,000 signatures from the 5' ends of polyadenylated products of miRNA-mediated mRNA decay, is
217 ogy from Pacific Biosciences to sequence the polyadenylated RNA complement of a pooled set of 20 huma
218 he viral genome is a single 7,400-nucleotide polyadenylated RNA encoding 11 proteins in a single open
220 entary DNA samples, reverse-transcribed from polyadenylated RNA obtained from human liver tissue.
225 ughput method for reliable identification of polyadenylated RNA termini, and we apply this method, ca
226 rine Upregulated Gene 1 (TUG1) is a spliced, polyadenylated RNA that does not encode any open reading
227 quantification of the full range of cellular polyadenylated RNA transcripts using a Helicos Genetic A
228 Because RBDmap relies on the isolation of polyadenylated RNA via oligo(dT), it will not provide RN
229 In addition, sar1 sar3 plants accumulate polyadenylated RNA within the nucleus, indicating that S
230 Following RNA extraction and isolation of polyadenylated RNA, a 5'-RNA adapter that includes an Mm
231 el approach to prepare 3' end fragments from polyadenylated RNA, and mapped the position of the poly(
232 trated that XTUT7 repressed translation of a polyadenylated RNA, to which it added a distinct number
234 onine serine repeat protein (Gts1p), nuclear polyadenylated RNA-binding protein 3, and minichromosome
240 is required for the 3'-end processing of non-polyadenylated, RNAPII-dependent, uridylate-rich, small
241 of human PAPD1, a noncanonical PAP that can polyadenylate RNAs in the mitochondria (also known as mt
242 t hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in Drosophil
243 generation sequencing to analyze and compare polyadenylated RNAs from abortive MOCV infections of sev
244 associations of human nuclear and cytosolic polyadenylated RNAs longer than 200 nucleotides (nt) and
246 number that gave rise to heterogeneous Trf4p-polyadenylated RNAs with lengths of approximately 250-50
247 toplasm after its nuclear export, to degrade polyadenylated RNAs, such as mRNAs, pre-mRNAs, or those
254 ation-dependent histone mRNAs, which are not polyadenylated, share factors involved in 3' end formati
255 roborated by the finding that the proximally polyadenylated short DOG1 mRNA is translated in vivo and
257 and characterized methylguanosine-capped and polyadenylated small RNAs (CPA-sRNAs) by using different
259 wild-type, pre-tRNA(i)(Met) accumulates as a polyadenylated species, whose abundance and length distr
262 idues, which are distinct in length from the polyadenylate tail added to other plant RNAs for exosome
263 ap-defective polymerases lacked an authentic polyadenylate tail and instead contained 0 to 24 A resid
264 upting deadenylation with use of an internal polyadenylate tail did not block target repression.
267 B mRNA terminates with an mRNA destabilizing polyadenylate tract, resulting in this strain being unab
268 of these clones corresponded to a capped and polyadenylated transcript containing a large portion of
270 o examine murine gammaherpesvirus 68 (MHV68) polyadenylated transcript expression in a time course of
271 ed by a 28-nucleotide transcript and long 3'-polyadenylated transcript initiated with non-canonical G
272 miR-378* and thus renders the alternatively polyadenylated transcript insusceptible to miR-378*-medi
273 analyses of MeCP2 protein and alternatively polyadenylated transcript levels were performed by laser
274 PCR and mRNA-seq detect a single capped and polyadenylated transcript that encodes processed forms o
275 t 49% (human), 31% (mouse), and 28% (rat) of polyadenylated transcription units have alternative poly
276 to contribute only a small percentage of the polyadenylated transcriptome in some RNA-Seq experiments
277 RNA sequencing (RNA-seq) to characterize the polyadenylated transcriptomes of human and mouse platele
278 the ENE-controlled rapid-decay mechanism for polyadenylated transcripts comprises a nuclear pre-mRNA
280 RRP6 result in the accumulation of aberrant polyadenylated transcripts from small nucleolar RNA gene
282 hroughput sequencing targeting the 3' end of polyadenylated transcripts in archived tumors from 24 ad
283 served that intron retention is prevalent in polyadenylated transcripts in resting CD4(+) T cells and
285 n species has identified genes encoding long polyadenylated transcripts that do not contain ORFs of l
286 ng element, the ENE, which allows intronless polyadenylated transcripts to accumulate to high nuclear
288 me capture methods to identify RBPs bound to polyadenylated transcripts within the first 2 h of Droso
289 for high-throughput sequencing of 3' ends of polyadenylated transcripts, and used it to globally map
290 ers fundamentally from normal termination in polyadenylated transcripts, as it leads to transcript de
291 a method is described to concurrently remove polyadenylated transcripts, prokaryotic rRNA, and eukary
294 more abundant than the other introns within polyadenylated transcripts; we classified these as "deta
295 n non-translating mRNPs, and the presence of polyadenylated uncapped mRNA in mRNPs was confirmed by s
298 he virally encoded poly(A) polymerase, which polyadenylates viral transcripts, also mediates 3' polya
299 ding P19-generated transcripts are primarily polyadenylated within the central intron and not efficie
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