ライフサイエンスコーパス: polyadenylated

1 y cleavage by RNase P and are capped but not polyadenylated.

2 ense transcripts that were not capped and/or polyadenylated.

3 transcribed by RNA polymerase II but are not polyadenylated.

4 s are the only eukaryotic mRNAs that are not polyadenylated.

5 NAs are the only metazoan mRNAs that are not polyadenylated.

6 gation complexes are efficiently cleaved and polyadenylated.

7 lymerase I or III and are not believed to be polyadenylated.

8 3'UTR is unusually long and is alternatively polyadenylated.

9 verified that bound mRNA remained intact and polyadenylated.

10 , are capped but, unlike host mRNAs, are not polyadenylated.

11 e 70S complex were unusual in that they were polyadenylated 100 to 200 nucleotides downstream of the

12 ncreases in the number of mRNA isoforms with polyadenylated 3' ends that map to 5'-untranslated regio

13 Here we show that polyadenylated 3' termini in three yeast species (Saccha

14 ments for two yeast snoRNA genes also direct polyadenylated 3'-end formation in the context of an mRN

15 all si/miRNA-sized fragments, (ii) uncapped, polyadenylated 3-prime fragments that encode the conserv

16 g tPA is present in dendrites and is rapidly polyadenylated after glutamate stimulation.

17 ut the day, some newly synthesized rRNAs are polyadenylated and degraded in the nucleus in a robustly

18 The ASFMR1 transcript is spliced, polyadenylated and exported to the cytoplasm.

19 es and an H3 gene that encode mRNAs that are polyadenylated and expressed at 5- to 10-fold lower leve

20 anscripts produced tend to be unspliced, non-polyadenylated and expressed at levels 10 to 100-fold lo

21 from the last (most telomeric) D4Z4 unit is polyadenylated and has two introns in its 3-prime untran

22 replication-dependent histone mRNAs are not polyadenylated and instead end in a conserved stem loop

23 The ORF-E transcript is polyadenylated and is expressed early when cultured bovi

24 By separating RNA into polyadenylated and nonpolyadenylated fractions, we showe

25 ess, we examined >1 billion RNA-seq reads of polyadenylated and nonpolyadenylated RNA from differenti

26 mplex is involved in the 3' end formation of polyadenylated and nonpolyadenylated RNA polymerase II t

27 We observed that both polyadenylated and nonpolyadenylated RNA syntheses decli

28 Sites of transcription of polyadenylated and nonpolyadenylated RNAs for 10 human c

29 been implicated in the transcription of both polyadenylated and nonpolyadenylated RNAs, Paf1C had not

30 ome an interleaved network of both annotated polyadenylated and nonpolyadenylated transcripts, includ

31 ep, multiple-stage reaction, where RNAs were polyadenylated and reverse-transcribed at the same time.

32 1 protein is downregulated while its mRNA is polyadenylated and stable.

33 cific RNA-seq to deeply profile lncRNAs from polyadenylated and total RNA obtained from human neocort

34 The m169 transcript is cytoplasmic, capped, polyadenylated, and interacts with miRNA-27 through seed

35 ng antisense RNA, asDOG1, that is 5' capped, polyadenylated, and relatively stable.

36 re-miRNAs) than pri-miRNAs that are cleaved, polyadenylated, and released.

37 howed that pc7 transcripts are expressed and polyadenylated, and that the PC7 precursor protein under

38 Thus, TAGKO transcripts are prematurely polyadenylated, and truncated proteins are predicted to

39 , to control the expression of alternatively polyadenylated antisense RNAs at the locus encoding the

40 The only eukaryotic mRNAs that are not polyadenylated are the replication-dependent histone mRN

41 es for PAP I in wild-type cells, are rapidly polyadenylated as PAP I levels increase, leading to dram

42 t of our knowledge, this description of both polyadenylated as well as nonpolyadenylated lncRNA trans

43 RNAs generated from upstream promoters were polyadenylated at (pA)p and hence not spliced.

44 The steady-state level of RNAs polyadenylated at (pA)p is independent of the promoter u

45 RNAs polyadenylated at (pA)p2 comprise approximately 10% of B

46 ncode the viral nonstructural proteins, were polyadenylated at a high efficiency at a polyadenylation

47 m of (pA)p, primarily readthrough (pA)p, are polyadenylated at a more distal site at the 3' end of th

48 d from the upstream P7 and P19 promoters are polyadenylated at a site in the central intron ((pA)p);

49 de the viral Rep proteins, are predominantly polyadenylated at a site within the intron [(pA)p].

50 s, primarily extended through (pA)p and were polyadenylated at a site, (pA)d, located at the right en

51 ng patterns are used, and each type is found polyadenylated at either the 3' end of the genome (the d

52 stranded positive-sense RNA molecule that is polyadenylated at its 3' end and covalently linked to a

53 They were polyadenylated at multiple sites within 3 kb downstream

54 that upstream antisense RNAs are cleaved and polyadenylated at poly(A) sites (PASs) shortly after ini

55 gonucleotide prevented B19V mRNA transcripts polyadenylated at the (pA)d site during B19V infection o

56 a sufficient number of B19V mRNA transcripts polyadenylated at the distal polyadenylation site ((pA)d

57 s generated by the proximal P41 promoter are polyadenylated at the distal polyadenylation site at the

58 d version of the full-length GP mRNA that is polyadenylated at the editing site and thus lacks a stop

59 Almost all eukaryotic mRNAs must be polyadenylated at their 3' ends to function in protein s

60 RNAs encoding histones are cleaved, but not polyadenylated at their 3' ends.

61 rst report to show that the highly expressed polyadenylated BamHI A rightward transcripts (BART) vira

62 ential regulatory properties of the spliced, polyadenylated BART RNAs, a full-length cDNA clone of on

63 The decay of 5' capped, polyadenylated bcl-2 mRNA transcripts containing ARE-1 w

64 In metazoans, histone mRNAs are not polyadenylated but end in a conserved stem-loop.

65 g the replication-dependent histones are not polyadenylated but end in a unique 26 nucleotide stem-lo

66 istone mRNAs are the only mRNAs that are not polyadenylated but instead end in a stem-loop which has

67 -responsive gene), which is both spliced and polyadenylated but is strictly localized in nuclei.

68 sequences present in BIC RNA, a spliced and polyadenylated but non-protein-coding RNA that accumulat

69 recently that sno-lncRNAs are not capped or polyadenylated but rather are terminated on each end by

70 ammalian mRNAs because they are not normally polyadenylated but, rather, are cleaved following a 3' s

71 ackaged into complete ribosomal subunits are polyadenylated by the poly(A) polymerase PAPD5 and degra

72 hat the nuclear-restricted pre-ribosomes are polyadenylated by TRAMP and degraded by the exosome.

73 The noncoding RNAs were polyadenylated, capped, and chromatin associated.

74 lated effectively in the presence of capped, polyadenylated cellular mRNAs is unknown.

75 NA metabolism events, we identify non-coding polyadenylated cis natural antisense transcripts (cis-NA

76 mbryos had apparently normal levels of fully polyadenylated compared to deadenylated GM-CSF mRNA and

77 roteins produce mRNAs that, instead of being polyadenylated, contain a unique 3' end structure.

78 in the 3' long terminal repeat (LTR) was not polyadenylated detectably in vitro; however, if the tran

79 However, when capped and polyadenylated dicistronic RNAs were synthesized in vitr

80 protein isoform produced from the proximally polyadenylated DOG1 mRNA is a key player in the establis

81 ut the mechanisms by which these genomes are polyadenylated during viral replication remain obscure.

82 structure and transcription of D4Z4-encoded polyadenylated DUX4 mRNA in muscle.

83 ation reactions has no effect on turnover of polyadenylated edited RNA.

84 As contain no introns, and the mRNAs are not polyadenylated, ending instead in a conserved stem-loop

85 only eukaryotic cellular mRNAs that are not polyadenylated, ending instead in a conserved stem-loop.

86 ng to determine the precise 5'-capped and 3'-polyadenylated ends of postreplicative RNAs.

87 , yielding a comprehensive atlas of 62,000 polyadenylated ends.

88 Using rG4-seq on polyadenylated-enriched HeLa RNA, we generated a global

89 We investigated how the long, polyadenylated Evf2 noncoding RNA regulates transcriptio

90 svirus produces a 1077 nucleotide noncoding, polyadenylated, exclusively nuclear RNA called PAN that

91 f 44 microRNAs (miRNAs), and the spliced and polyadenylated exons form nuclear non-protein-coding RNA

92 vation of the functional short alternatively polyadenylated form of the DOG1 mRNA.

93 f products was shifted to favor the distally polyadenylated form.

94 ipt, which attenuates the degradation of the polyadenylated form.

95 Polyadenylated forms of the 27S pre-rRNA and the 25S rRN

96 essing of the major pri-miR171a, spliced and polyadenylated forms of which accumulate in plants homoz

97 und that the drug causes the accumulation of polyadenylated fragments of the 27S rRNA precursor and t

98 ression of pre-mRNAs prematurely cleaved and polyadenylated from cryptic polyadenylation signals (PAS

99 was established for quantitative analysis of polyadenylated full-length (fl) and truncated (tr) HBV R

100 Interestingly, GppppA-capped and polyadenylated full-length mRNAs were also found to be s

101 omplex required for production of proximally polyadenylated functional DOG1 transcript.

102 substantial posttranscriptional increase in polyadenylated GAL1 3' ends.

103 The polyadenylated H3.1 mRNA induced by arsenic was not susc

104 lular mRNA, translation of the uncapped, non-polyadenylated hepatitis C virus (HCV) genome occurs ind

105 results in accumulation of small amounts of polyadenylated histone mRNA and nascent read-through tra

106 There are also genes encoding polyadenylated histone mRNAs, which encode histone varia

107 f 7SK led to an enhanced ratio of cleaved to polyadenylated histone transcripts, an effect dependent

108 s2 depletion, concurrent with an increase in polyadenylated histone transcripts.

109 Processive, polyadenylated HIV-1 mRNAs were also present at a low le

110 the question of how viral RNA is efficiently polyadenylated in the absence of splicing.

111 Most eukaryotic mRNAs are polyadenylated in the nucleus, and the poly(A)-tail is r

112 ranscripts encoding the capsid proteins were polyadenylated in the right-hand terminal palindrome.

113 A 5'-capped, polyadenylated in vitro transcript derived from the 3'-u

114 t approximately 85% of viral transcripts are polyadenylated in vivo.

115 A-less promoters and are neither spliced nor polyadenylated; instead, 3' processing is directed by a

116 aordinary diversity of correctly spliced and polyadenylated intergenic transcripts.

117 ong the intervening DNA, synthesizing short, polyadenylated, intergenic RNAs to ultimately loop with

118 prise approximately 10% of B19 RNAs that are polyadenylated internally.

119 e Expression) sequencing to globally resolve polyadenylated isoform structures in replicating Epstein

120 lncRHOXF1 is a spliced and polyadenylated lncRNA about 1 kb in length that is found

121 ockd (lncRNA downstream of Cdkn1b), a 434-nt polyadenylated lncRNA originating 4 kb 3' to the Cdkn1b

122 Analysis of the mouse erythro-megakaryocytic polyadenylated lncRNA transcriptome indicates that ~75%

123 We used RNA sequencing to identify 1109 polyadenylated lncRNAs expressed in erythroblasts, megak

124 et and another Alu element in a cytoplasmic, polyadenylated long non-coding RNA (lncRNA).

125 ion signal with sequences derived from a non-polyadenylated long non-coding RNA (MALAT1), which can f

126 Capped and polyadenylated long noncoding RNAs (lncRNAs) are shown t

127 Polyadenylated mature mRNAs are the focus of standard tr

128 sed on elevated affinity interaction between polyadenylated miRNA and bare gold electrode.

129 responses together with increased levels of polyadenylated mitochondrial transcripts.

130 al membrane fraction preferentially degraded polyadenylated mitochondrially and non-mitochondrially e

131 xon 2 resulting in the production of a small polyadenylated mRNA (HTTexon1) that encodes the highly p

132 ate of labeling of rp mRNA relative to total polyadenylated mRNA changed very little after stimulatio

133 the antigenome, and (iii) the less abundant polyadenylated mRNA for the small delta protein.

134 of target mRNAs produce diagnostic uncapped, polyadenylated mRNA fragments.

135 We demonstrate that hos1 mutants accumulate polyadenylated mRNA in the nucleus and that the circadia

136 adaptors that flag alternatively spliced and polyadenylated mRNA isoforms as cargo ready for the cyto

137 roteins (sFlt1s) produced from alternatively polyadenylated mRNA isoforms.

138 otein factors necessary for 3' processing of polyadenylated mRNA precursors are well known.

139 he oligo(dT)-primed reverse transcription of polyadenylated mRNA templates used to generate EST cDNA

140 its exact complement (the antigenome), and a polyadenylated mRNA that acts as a template for the smal

141 principally to a genomic region producing a polyadenylated mRNA that encodes a protein.

142 nt splicing of exon 1 HTT results in a short polyadenylated mRNA that is translated into an exon 1 HT

143 bed exclusively in testis, where the spliced polyadenylated mRNA was detected.

144 About 70% of total polyadenylated mRNA was in the polysome fraction in all

145 ated in vitro and also when m(7)G-capped and polyadenylated mRNA was transiently transfected into 293

146 ion factors, mRNA binding proteins, and most polyadenylated mRNA.

147 SG-PB docking, and impaired preservation of polyadenylated mRNA.

148 Polyadenylated mRNAs and replication-dependent histone m

149 mplexes-one specifically crafted to generate polyadenylated mRNAs and the other to generate nonpolyad

150 requires shortened/no poly(A)-tail targets; polyadenylated mRNAs are partially activated upon PAIP2

151 During heat shock, most polyadenylated mRNAs are retained in the nucleus, wherea

152 Together, these results suggest that polyadenylated mRNAs can enter P-bodies, and an mRNP com

153 Genes encoding polyadenylated mRNAs depend on their poly(A) signals for

154 d of the genome followed by 5'-capped and 3'-polyadenylated mRNAs from internal genes by a stop-start

155 They are expressed as polyadenylated mRNAs in fibroblasts differentiated in vi

156 of this system, including the prevalence of polyadenylated mRNAs in the bacterium, are still poorly

157 Transcription termination for genes encoding polyadenylated mRNAs requires a functional poly(A) signa

158 erminal portion of DUX4 and (iii) capped and polyadenylated mRNAs that contain the double-homeobox do

159 Polyadenylated mRNAs were captured by oligo-dT primers a

160 s the genomic RNA to produce five capped and polyadenylated mRNAs with the 5'-terminal structure 7mGp

161 Since PABP1 binds to all polyadenylated mRNAs, and is involved in translation ini

162 PABPC1 antagonizes uridylation of polyadenylated mRNAs, contributing to the specificity fo

163 ssed in terminally differentiated tissues as polyadenylated mRNAs, likely serving as replacement hist

164 eta-lactamase family generate the 3' ends of polyadenylated mRNAs, nonpolyadenylated histone mRNAs, a

165 n-independent histones, which are encoded by polyadenylated mRNAs, persists outside of S phase.

166 er half of human genes produce alternatively polyadenylated mRNAs, suggesting that regulated polyaden

167 , similar to the mechanism of translation of polyadenylated mRNAs.

168 ns two sets of histone genes that encode non-polyadenylated mRNAs.

169 etween 3' end formation of histone mRNAs and polyadenylated mRNAs.

170 istone genes that encode histone variants as polyadenylated mRNAs.

171 amyxoviruses produce capped, methylated, and polyadenylated mRNAs.

172 quently yielded an accumulation of shortened polyadenylated mtRNA species and impaired mitochondrial

173 These capped, polyadenylated ncRNAs are transcribed across the large i

174 The remainder associates with non-polyadenylated non-coding transcription.

175 s, 19.4, 43.7, and 36.9% were observed to be polyadenylated, nonpolyadenylated, and bimorphic, respec

176 t REF/Aly is recruited to the KSHV noncoding polyadenylated nuclear (PAN) RNA by ORF57.

177 osi's sarcoma-associated herpes virus (KSHV) polyadenylated nuclear (PAN) RNA facilitates lytic infec

178 Stability of the long noncoding-polyadenylated nuclear (PAN) RNA from Kaposi's sarcoma-a

179 ith a 9-nucleotide (nt) core element of KSHV polyadenylated nuclear (PAN) RNA, a viral long noncoding

180 es a highly abundant, nuclear noncoding RNA, polyadenylated nuclear (PAN) RNA, which contains an elem

181 tial for the nuclear accumulation of a viral polyadenylated nuclear (PAN) RNA.

182 Lytic KSHV expresses polyadenylated nuclear RNA (PAN RNA), a long noncoding R

183 ma-associated herpesvirus (KSHV) expresses a polyadenylated nuclear RNA (PAN RNA).

184 t, long, noncoding transcript referred to as polyadenylated nuclear RNA (PAN RNA).

185 , ORF59, K8alpha, K8.1, or a higher level of polyadenylated nuclear RNA after butyrate induction and

186 the Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA contains a 79-nt cis-acting e

187 monomeric red fluorescent protein 1 (mRFP1), polyadenylated nuclear RNA promoter (pPAN)-enhanced gree

188 tains the lacZ gene under the control of the polyadenylated nuclear RNA promoter, known to be strongl

189 the Kaposi's sarcoma-associated herpes virus polyadenylated nuclear RNA) are not efficiently processe

190 paired in activating direct targets, such as polyadenylated nuclear RNA, and indirect targets, such a

191 ranscriptome showed that several viral RNAs (polyadenylated nuclear RNA, open reading frame 58 [ORF58

192 which we named lncRNA-CMPK2, was a spliced, polyadenylated nuclear transcript that was induced by IF

193 ers of two other KSHV DE genes encoding PAN (polyadenylated nuclear) RNA and MTA (ORF57), which was a

194 bearing two C-G*C(H+) interrupts), and (3) a polyadenylated nuclear-nuclear retention element complex

195 130 kb upstream of miR-21, are spliced, and polyadenylated only a few hundred base pairs upstream of

196 Capped and polyadenylated ORF0 mRNAs are present in the cytoplasm,

197 Nuclear polyadenylated (poly(A)) RNA in ZC3H3-depleted cells is

198 ts and reconstituted exosomes using AU-rich, polyadenylated (poly[A]), generic, and structured RNA su

199 in which we identify 72 factors required for polyadenylated [poly-(A(+))] mRNA export from the nucleu

200 idopsis continues to suggest the presence of polyadenylated (polyA) transcripts originating from pres

201 eviously undescribed prematurely cleaved and polyadenylated pre-mRNAs, some of which contain novel OR

202 or is required for processing of histone and polyadenylated pre-mRNAs.

203 dependent surveillance pathway that degrades polyadenylated precursor rRNAs.

204 as mRNAs, pre-mRNAs, or those RNAs that are polyadenylated prior to their degradation in the nucleus

205 found that human NLRP3 can be alternatively polyadenylated, producing a short 3'-UTR isoform that ex

206 rt that the yeast RPB2 gene is alternatively polyadenylated, producing two mRNAs with different lengt

207 d >28,000,000 signatures from the 5' ends of polyadenylated products of miRNA-mediated mRNA decay, is

208 , whilst mt-rRNAs and mt-mRNAs are oligo- or polyadenylated, respectively.

209 BMP2 mRNAs are alternatively polyadenylated, resulting in mRNAs with distinct 3'-untr

210 We now demonstrate that Slr1 binds to polyadenylated RNA and that its intracellular localizati

211 en the steady-state levels of CAR1-specific, polyadenylated RNA and the degree of arginase induction

212 rent biochemistries, with one examining only polyadenylated RNA and the other total RNA.

213 wn without the inducer contained very little polyadenylated RNA capable of hybridizing to the isolate

214 ogy from Pacific Biosciences to sequence the polyadenylated RNA complement of a pooled set of 20 huma

215 cing coincides with nuclear retention of non-polyadenylated RNA derived from MuDR and recently descri

216 e cloned gene was used as a probe to analyze polyadenylated RNA derived from wild-type and mutant cel

217 he viral genome is a single 7,400-nucleotide polyadenylated RNA encoding 11 proteins in a single open

218 Picornaviruses have 3' polyadenylated RNA genomes, but the mechanisms by which

219 entary DNA samples, reverse-transcribed from polyadenylated RNA obtained from human liver tissue.

220 Furthermore, a polyadenylated RNA of 1.4 kb was identified downstream o

221 A polyadenylated RNA of 3.0 kb (T3.0) is transcribed from

222 ination of nonpolyadenylated as well as some polyadenylated RNA polymerase II transcripts.

223 This transcription is observed in polyadenylated RNA samples and appears to be derived fro

224 ughput method for reliable identification of polyadenylated RNA termini, and we apply this method, ca

225 rine Upregulated Gene 1 (TUG1) is a spliced, polyadenylated RNA that does not encode any open reading

226 quantification of the full range of cellular polyadenylated RNA transcripts using a Helicos Genetic A

227 Because RBDmap relies on the isolation of polyadenylated RNA via oligo(dT), it will not provide RN

228 In addition, sar1 sar3 plants accumulate polyadenylated RNA within the nucleus, indicating that S

229 Following RNA extraction and isolation of polyadenylated RNA, a 5'-RNA adapter that includes an Mm

230 el approach to prepare 3' end fragments from polyadenylated RNA, and mapped the position of the poly(

231 Electrophoretic analysis of polyadenylated RNA, followed by transfer to nitrocellulo

232 trated that XTUT7 repressed translation of a polyadenylated RNA, to which it added a distinct number

233 Men epsilon is a 3.2-kb polyadenylated RNA, whereas Men beta is an approximately

234 onine serine repeat protein (Gts1p), nuclear polyadenylated RNA-binding protein 3, and minichromosome

235 We sequenced polyadenylated RNA-derived complementary DNAs from 92 ps

236 O2 into enlarged nuclear speckles containing polyadenylated RNA.

237 s that contain pre-mRNA splicing factors and polyadenylated RNA.

238 nscripts (BARTs) are the most abundant viral polyadenylated RNA.

239 y can be harnessed to identify alternatively polyadenylated RNA.

240 is required for the 3'-end processing of non-polyadenylated, RNAPII-dependent, uridylate-rich, small

241 t hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in Drosophil

242 generation sequencing to analyze and compare polyadenylated RNAs from abortive MOCV infections of sev

243 tochondria, where they are directly bound to polyadenylated RNAs in vivo.

244 associations of human nuclear and cytosolic polyadenylated RNAs longer than 200 nucleotides (nt) and

245 Finally, we demonstrate that degradation of polyadenylated RNAs occurs in the 3' to 5' direction thr

246 Formation of the 3' end of these non-polyadenylated RNAs requires a specialized 3' box elemen

247 Non-coding non-polyadenylated RNAs were among the key Hox targets, with

248 number that gave rise to heterogeneous Trf4p-polyadenylated RNAs with lengths of approximately 250-50

249 toplasm after its nuclear export, to degrade polyadenylated RNAs, such as mRNAs, pre-mRNAs, or those

250 on of ORF59 RNA and RBM15's association with polyadenylated RNAs.

251 The levels of polyadenylated rRNAs are dramatically increased in strai

252 The existence of polyadenylated rRNAs may reflect a quality-control mecha

253 Polyadenylated rRNAs reside mainly within the nucleus an

254 ation-dependent histone mRNAs, which are not polyadenylated, share factors involved in 3' end formati

255 roborated by the finding that the proximally polyadenylated short DOG1 mRNA is translated in vivo and

256 observed transcript 3' end heterogeneity and polyadenylated small nucleolar RNAs.

257 and characterized methylguanosine-capped and polyadenylated small RNAs (CPA-sRNAs) by using different

258 s of the Arabidopsis thaliana transcriptome (polyadenylated, small, and degrading RNAs).

259 wild-type, pre-tRNA(i)(Met) accumulates as a polyadenylated species, whose abundance and length distr

260 how that genes are also flanked by sense, 3' polyadenylated sRNAs that are likely to be capped.

261 promote the deadenylation of ARE-containing, polyadenylated substrates by PARN.

262 chet helix that influences Mtr4 affinity for polyadenylated substrates.

263 cts were multigenomic in length, some stable polyadenylated SV40-specific RNA similar in size and seq

264 of these clones corresponded to a capped and polyadenylated transcript containing a large portion of

265 An abundant, spliced, internally polyadenylated transcript encoded the viral NP1 protein

266 o examine murine gammaherpesvirus 68 (MHV68) polyadenylated transcript expression in a time course of

267 ed by a 28-nucleotide transcript and long 3'-polyadenylated transcript initiated with non-canonical G

268 miR-378* and thus renders the alternatively polyadenylated transcript insusceptible to miR-378*-medi

269 analyses of MeCP2 protein and alternatively polyadenylated transcript levels were performed by laser

270 PCR and mRNA-seq detect a single capped and polyadenylated transcript that encodes processed forms o

271 We now report another polyadenylated transcript that is transcribed on the str

272 t 49% (human), 31% (mouse), and 28% (rat) of polyadenylated transcription units have alternative poly

273 to contribute only a small percentage of the polyadenylated transcriptome in some RNA-Seq experiments

274 RNA sequencing (RNA-seq) to characterize the polyadenylated transcriptomes of human and mouse platele

275 the ENE-controlled rapid-decay mechanism for polyadenylated transcripts comprises a nuclear pre-mRNA

276 Ratios of encapsidated readthrough and polyadenylated transcripts for vectors with wild-type an

277 RRP6 result in the accumulation of aberrant polyadenylated transcripts from small nucleolar RNA gene

278 Noncoding functions of such polyadenylated transcripts have been elucidated in only

279 hroughput sequencing targeting the 3' end of polyadenylated transcripts in archived tumors from 24 ad

280 served that intron retention is prevalent in polyadenylated transcripts in resting CD4(+) T cells and

281 Here, we show that intron-less polyadenylated transcripts such as PAN RNA and beta-glob

282 n species has identified genes encoding long polyadenylated transcripts that do not contain ORFs of l

283 ng element, the ENE, which allows intronless polyadenylated transcripts to accumulate to high nuclear

284 We curated polyadenylated transcripts with limited protein-coding c

285 me capture methods to identify RBPs bound to polyadenylated transcripts within the first 2 h of Droso

286 for high-throughput sequencing of 3' ends of polyadenylated transcripts, and used it to globally map

287 ers fundamentally from normal termination in polyadenylated transcripts, as it leads to transcript de

288 a method is described to concurrently remove polyadenylated transcripts, prokaryotic rRNA, and eukary

289 f this enzyme to deadenylate ARE-containing, polyadenylated transcripts, while having no effect on tr

290 s greater than those for 98% of all cellular polyadenylated transcripts.

291 on of 17 distinct, likely non-protein-coding polyadenylated transcripts.

292 mulated the deadenylation of ARE-containing, polyadenylated transcripts.

293 more abundant than the other introns within polyadenylated transcripts; we classified these as "deta

294 midines that created termination codons when polyadenylated, type II had downstream termination codon

295 n non-translating mRNPs, and the presence of polyadenylated uncapped mRNA in mRNPs was confirmed by s

296 The 5' ends of polyadenylated, uncapped mRNAs from Arabidopsis were dir

297 We found that about 85% of rp mRNA is polyadenylated under all growth conditions.

298 HuR mRNA exists as three alternatively polyadenylated variants, a 1.5-kb testes-specific mRNA i

299 ding P19-generated transcripts are primarily polyadenylated within the central intron and not efficie

300 f Ty1 cDNA to prime reverse transcription of polyadenylated Y' RNA within Ty1 VLPs.