ライフサイエンスコーパス: polyamine oxidase

1 substrate to the flavin as the mechanism of polyamine oxidase.

2 he metabolism of polyamines to putrescine by polyamine oxidase.

3 d as regards Y444 in MAO A and Y439 in plant polyamine oxidase.

4 This residue is also conserved in other polyamine oxidases.

5 ivity of the mouse homologue of this enzyme (polyamine oxidase 1 (PAO1)) by 6 h in parallel with orni

6 al ischemia stimulates increased activity of polyamine oxidase, a ubiquitous enzyme that catabolizes

7 ed to 1,3,-diaminopropane (DAP), probably by polyamine oxidase action.

8 r by other arginine-dependent NO systems, by polyamine oxidase activity or non-enzymatically by low p

9 Brain polyamine oxidase activity was increased significantly w

10 lying cerebral damage during ischemia, brain polyamine oxidase activity was measured in rats subjecte

11 oguanidine and chloroquine) attenuates brain polyamine oxidase activity, prevents the production of 3

12 n was posttranscriptional and independent of polyamine oxidase activity.

13 with two structurally distinct inhibitors of polyamine oxidase (aminoguanidine and chloroquine) atten

14 broblasts are shown to have higher levels of polyamine oxidase, an enzyme involved in the formation o

15 Dose-dependent inhibition of polyamine oxidase, an enzyme that oxidizes acetylated po

16 The major aldehydes produced by polyamine oxidase and amine oxidases include the 2-alken

17 gs to the family of amine oxidases including polyamine oxidase and monoamine oxidase (MAO).

18 The suggestion that polyamine oxidase and monoamine oxidase may have structu

19 uction of SSAT upregulated the expression of polyamine oxidase and resulted in the reduction of cellu

20 of the main polyamine enzymes analyzed (ODC, polyamine oxidase, and spermine synthase) and reduction

21 The major catabolic products of polyamine oxidase are putrescine and 3-aminopropanal.

22 ee-dimensional modeling of MAO A and B using polyamine oxidase as template suggests that the overall

23 ressor CoREST and a protein with homology to polyamine oxidases as components of CoREST-HDAC.

24 In mammalian cells, the flavoprotein polyamine oxidase catalyzes a key step in the catabolism

25 idered together, these results indicate that polyamine oxidase-derived 3-aminopropanal is a mediator

26 Thus, this is the classical polyamine oxidase (EC 1.5.3.11) that is defined as the e

27 enzyl-1,4-diaminobutanes by the flavoprotein polyamine oxidase from mouse have been determined to gai

28 Polyamine oxidase functions in the polyamine catabolic p

29 asure the growth differences, we developed a polyamine oxidase fvpo1 mutant in this fungus that fails

30 Recombinant cotton polyamine oxidase (GhPAO) was found to catalyse the conv

31 rsion of spermine to spermidine by the human polyamine oxidase h1, also called spermine oxidase, has

32 Inhibition of polyamine oxidase in hematopoietic cells by a specific i

33 orticosteroid-binding protein in yeast and a polyamine oxidase in maize.

34 The latter was confirmed with the polyamine oxidase inhibitor MDL-75275 and the antioxidan

35 A small molecule polyamine oxidase inhibitor N,N'-butanedienyl butanediam

36 placental bone morphogenetic protein (PLAB), polyamine oxidase isoform 1 (PAOh1) and E74-like factor

37 to test the suggestion that MAO A and plant polyamine oxidase may have structural homology, tyrosyl

38 pecific demethylase 1 (LSD1), a homologue of polyamine oxidases, may broadly repress gene expression.

39 dehyde, 3-aminopropanal (3-AP), a product of polyamine oxidase metabolism of spermine and spermidine.

40 Fms1 has polyamine oxidase (PAO) activity, which converts spermin

41 tly higher spermidine content, and increased polyamine oxidase (PAO) activity.

42 A polyamine oxidase (PAO) gene was identified and cloned b

43 The catalysis of polyamines by the SSAT/polyamine oxidase (PAO) pathway produces H2O2 as one pro

44 midine/spermine acetyltransferase (SSAT) and polyamine oxidase (PAO) were determined using a new high

45 f three regions of pure bovine N1-acetylated polyamine oxidase (PAO) were obtained and used to search

46 yltransferase (SSAT; encoded by Sat1) and by polyamine oxidase (PAO), and has a major role in energy

47 nd the flavin adenine dinucleotide-dependent polyamine oxidase (PAO).

48 Mammalian polyamine oxidases (PAOs) catalyze the oxidation of N1-a

49 Arabidopsis thaliana factors, a SWIRM domain polyamine oxidase protein, AtSWP1, and a plant-specific

50 In the present study, polyamine oxidase specific for spermine and spermidine a

51 inished by co-treatment with an inhibitor of polyamine oxidase, suggesting that growth inhibition was

52 his enzyme is distinguishable from the plant polyamine oxidase that oxidizes spermine on the endo-sid

53 Based on the polyamine oxidase three-dimensional crystal structure, i

54 The levels of mRNA, protein, and activity of polyamine oxidase were increased in alveolar macrophages

55 By contrast, knockdown of polyamine oxidase (ZmPAO) significantly increased SCMV a