ライフサイエンスコーパス: polyanion

1 copurified lipid molecules, and a synthetic polyanion.

2 dependent on the net charge and size of the polyanion.

3 s intimate that NTHi P5 is associated with a polyanion.

4 10.3, and consistent with the inclusion of a polyanion.

5 e delta-isomer of the Keggin polyoxometalate polyanion.

6 ess and overall polarity of the triphosphate polyanion.

7 a-tryptase, and the beta-tryptase-activating polyanion.

8 occupied ER from the nucleus compared to the polyanions.

9 an autocatalytic process requiring accessory polyanions.

10 of cell wall (dltA) and cell membrane (mprF) polyanions.

11 viously observed structural stabilization by polyanions.

12 direct binding of PEDF to glycosaminoglycans/polyanions.

13 to interact with various glycosaminoglycans/polyanions.

14 nhibited by divalent cation-chelators and by polyanions.

15 in 4-sulfate and dermatan sulfate as the GAG polyanions.

16 roteins, prions bind nucleic acids and other polyanions.

17 ) is used as the recognition element for the polyanions.

18 line-earth, and rare-earth elements, and Sb4 polyanions.

19 concentration and the charge density of the polyanions.

20 ring anti-HIV activities with those of other polyanions.

21 conformational changes when complexing with polyanions.

22 oxidative damage, and host surface-specific polyanions.

23 s a slow reaction that can be accelerated by polyanions.

24 immunogenic complexes with heparin and other polyanions.

25 reduced activity and decreased activation by polyanions.

26 ies in the absence of nucleic acids or other polyanions.

27 filtration chromatography in the absence of polyanions.

28 hexakisphosphate is supplemented with other polyanions.

29 W9O34)2].35H2O (Na101-V2, sodium salt of the polyanion 1-V2), was synthesized, thoroughly characteriz

30 igated the interaction between five cellular polyanions (actin, tubulin, heparin, heparan sulfate, an

31 Polyanions activate IDE toward some substrates, yet an e

32 ey residue required for maximal activity and polyanion activation, although other cysteines affect po

33 residue also reduced activity and decreased polyanion activation.

34 states of the dimer that affect activity and polyanion activation.

35 DE toward some substrates, yet an endogenous polyanion activator has not yet been identified.

36 ized silica gel particles were coated with a polyanion and a polycation bearing thymine chromophores.

37 tor H where previous reports have identified polyanion and C3b-binding sites.

38 ed a monomer Mr of 163,000 in the absence of polyanions and a Mr of 607,000, corresponding to a tetra

39 f listing PABPs by the number of interacting polyanions and a string search for author surnames.

40 Herein, locations of binding sites for polyanions and C3b are reexamined rigorously by overexpr

41 the TFIIIB-DNA complex and its resistance to polyanions and high salt.

42 the complex and dynamic interactions between polyanions and Lipoplex, and the use of QP modeling to d

43 roved stability in the presence of competing polyanions and nuclease protection in serum relative to

44 were assembled by sequentially chemisorbing polyanions and polycations on miniature (5 x 10(-4) cm2)

45 can be used to deposit alternating layers of polyanions and polycations on the surface surrounding th

46 Over a thousand combinations of polyanions and polycations were tested to search for new

47 interactions with surface-associated C3b or polyanions and thereby diminish the ability of fH to reg

48 ment in the detection limits toward heparin (polyanion) and protamine (polycation) of at least 1 orde

49 oltage-dependent anion channel (VDAC), Konig polyanion, and 4,4'-diisothiocyanatostilbene-2,2'-disulf

50 PrP binds to polyanions, and RNAs were shown to promote the conversio

51 ptamers has the potential to induce anti-PF4/polyanion antibodies and a prothrombotic diathesis.

52 Yet the counterions for these polycations or polyanions are often ignored, even though they are imper

53 r of the alternative pathway (AP) that binds polyanions as well as complement activation fragments C3

54 This polyanion, as the dimethylammonium salt, shows a thermal

55 rubin oxidase from Myrothecium verrucaria, a polyanion at pH >4.1, and the polycationic redox copolym

56 result from a failure of FH to interact with polyanions at cell surfaces in the kidney.

57 both polycations at levels >/=10 mug/mL and polyanions at levels of >/=40 mug/mL by changing the dir

58 nal change resulting in the shielding of the polyanion backbone; this was monitored by a change in th

59 These polyanions bind to the film not only electrostatically b

60 a and the amino acids of PF4 contributing to polyanion binding are highly conserved, our results furt

61 pressed fragment encompassing the C-terminal polyanion binding site (complement control protein domai

62 activation, although other cysteines affect polyanion binding to a lesser extent.

63 wed the conformer specificity of the protein-polyanion binding to be monitored.

64 rstanding of the structural requirements for polyanion binding to dengue virus envelope protein has b

65 nanostructures can exhibit enantioselective polyanion binding.

66 he interactions between polyanions (PAs) and polyanion-binding proteins (PABPs) have been found to pl

67 We demonstrate that a large number of polyanion-binding proteins exist that contain multiple p

68 ature of cellular interiors, we propose that polyanion-binding proteins interact with a wide variety

69 InsPs and PtdInsPs interact with the polyanion-binding site located on an inner chamber wall

70 molecular weight dextran sulfate and heparin polyanions, but also was produced by beta-tryptase tetra

71 e cations that are attracted to nucleic acid polyanions, but have also showed that anions are exclude

72 Here we show that interaction with polyanions causes self-association forming tetramers of

73 is primarily electrostatic, because DNA-like polyanion chains (e.g. heparin and polyglutamate) can me

74 sed by immunoglobulin G directed against PF4/polyanion complexes.

75 Exploring polyanion compounds with high theoretical capacity such

76 be detected in heparin at only 2-mg/mL total polyanion concentration with a linear response (R(2) = 0

77 These contain the largest known discrete polyanion consisting only of main-group elements.

78 High charge-density polyanion contaminants and impurities in heparin can be

79 fects of the polyene antibiotic MS-8209, the polyanion dextran sulfate 500 (DS500), and Congo red wer

80 ling evidence that factor XIa binding to the polyanions, dextran sulfate and heparin, results in inhi

81 Here, by using polycation- and polyanion-directed intrafibrillar mineralization, we cha

82 r PrP(Sc) propagation, RNA and several other polyanions do not promote the propagation of mouse and v

83 chemoresistance gene survivin and two model polyanion drugs (suramin, heparin).

84 e contributions of three mechanisms by which polyanion drugs reduced the gene silencing activity of L

85 the concentrations used, excluding a general polyanion effect.

86 the membrane to cause the extraction of the polyanions from the sample into the membrane and potenti

87 = 4.97-5.30 A) and feature a two-dimensional polyanion [GaEH](2-) that corresponds to a corrugated he

88 Polyanions [GaEH](2-) are electron precise, and the hydr

89 We find that water-soluble polyanions generally accelerate the polymerization.

90 ned by the choice of transition metal and/or polyanion group in the structure.

91 hat the remarkable properties of Poly P as a polyanion have made it suited for a crucial role in the

92 Interestingly, binding of the polyanion heparin also leads to release of the C terminu

93 asminogen, as addition of excess NaCl or the polyanion heparin did not have any significant effect on

94 cting agents, cyclodextrin and nystatin, and polyanion heparin significantly inhibited virus entry.

95 pulations when either nonspecific DNA or the polyanion heparin was used.

96 ts competition by high concentrations of the polyanion heparin.

97 e residues of FH19-20, and competed with the polyanions heparin and DNA.

98 Further, an analogous polyanion (heparin)-sensitive electrode is used to estim

99 stries, including chalcogenides, oxides, and polyanions, highlighting merits and challenges of each c

100 ion and manipulation of this highly reactive polyanion in water is controlled exclusively by its coun

101 host was observed to strongly bind aromatic polyanions in water, including the fluorescent dye molec

102 These polyanions include heparan sulfate (HS), a glycosaminogl

103 receptors (SR-AI/II) recognize a variety of polyanions including bacterial cell wall products such a

104 nomenon by studying the ability of different polyanions, including DNA, ATP, heparin, and heparan sul

105 stingly, capsid reassembly can be induced by polyanions, including oligonucleotides, poly-glutamic ac

106 High molecular weight polyanions increased degradation of these anaphylatoxins

107 tween VP22.C1 and divalent cations and model polyanions indicate that Mg(2+), Zn(2+), oligonucleotide

108 ontrol protein domains 18-20) also exhibited polyanion-induced self-association, suggesting that the

109 of the chemokine platelet factor 4 (PF4) to polyanions induces heparin-induced thrombocytopenia, a p

110 These observations suggest that sulfated polyanions inhibit the invasion of erythrocytes by meroz

111 s antiviral activity and that it, like other polyanions, inhibits virus attachment.

112 c head groups are bound identically by these polyanions, irrespective of chirality.

113 A large-molecular-weight polyanion is found to possess lubricating properties for

114 The exact structure of polyanions is not important for in vitro capsid reassemb

115 des is functionally similar to that of other polyanions, is dependent on RSV G, and does not specific

116 s of all reactant moieties, the [Nb6O19](8-) polyanion, its Cs(+) counterions, and the DMMP substrate

117 Interaction with cell-surface polyanions like heparin is centrally important in the fu

118 2)K(2)[(MesCu)(2)Ge(4)](NH(3))(7.5) with the polyanion [(MesCu)(2)Ge(4)](4-).

119 ules in a purified system requires accessory polyanion molecules.

120 stom searches via four menus: protein names, polyanion names, the source species of the proteins and

121 Preyssler polyanions of general formula [LnP(5)W(30)O(110)](12-) (

122 ng and inhibitory effects of polycations and polyanions on HIV-1 infection are largely dependent on t

123 potential role for postattachment effects of polyanions on RSV entry.

124 The effects of several polyanions on the hydrolysis of the chromogenic substrat

125 er diffusely associated with the RNase P RNA polyanion or required for binding mature tRNA(Asp).

126 that cofactors such as nucleic acids, other polyanions, or lipids are non-obligatory for prion prote

127 The interactions between polyanions (PAs) and polyanion-binding proteins (PABPs)

128 d on proteolytic digestion of protamine, and polyanions (pentosan polysulfate and heparin) based on t

129 Blending the weak polyanion poly(acrylic acid), PAA, with the strong polya

130 ion poly(acrylic acid), PAA, with the strong polyanion poly(styrene sulfonate), PSS, to layer alterna

131 vely charged microdomains of the avidin, two polyanions, poly(acrylic acid-co-maleic acid) and poly(a

132 l activity of tPMP was also inhibited by the polyanions polyanetholsulfonic acid and polyaspartic aci

133 electron- electron repulsion present in the polyanion polyradicals.

134 c liquid and magnetically oriented rigid-rod polyanion provides widely tunable properties for use in

135 Planar potentiometric polycation and polyanion PSEs are prepared by incorporating tridodecylm

136 tions of the C-terminal domains prevent host polyanion recognition.

137 tion is unlikely since the concentrations of polyanions required for inhibition of small peptide hydr

138 nd succinylated PLL (SPLL) as polycation and polyanion, respectively, we demonstrated layer-by-layer

139 In contrast, at acidic pH addition of a polyanion resurrects enzyme activity.

140 via CCPs 1-4, CCPs 6-8 and CCPs 19-20, with polyanion-rich host surfaces that bear covalently attach

141 cement of the phosphodiester linkages of the polyanion RNA with guanidinium linkers (represented by g

142 on a reversible pulsed chronopotentiometric polyanion-selective membrane electrode for the detection

143 Lastly, it is shown that plasticizer-free polyanion-sensitive optodes based on an adsorbed layer o

144 ot due to binding of either substrate by the polyanions since only a decrease in V(max) without any e

145 A combination of polyanion size and charge allows the Keggin-type polyoxo

146 Here, we show that the presence of polyanions (SO4(2-) and HPO4(2-)) or lipids in the form

147 The polyanion, sodium poly(7-oxanorbornene-2-carboxylate), i

148 , the chemically generated radical anion and polyanion states, Xn-Hex(*-) and Xn-Hex(n(*-)), respecti

149 mulated in its utilization of UDP-glucose by polyanions such as heparin, the recombinant enzyme was s

150 Polyanions such as nucleoside phosphates or oligomers of

151 ies have shown that the co-administration of polyanions such as poly-L-aspartic acid (PAA) can both r

152 Polyanions such as polyglutamate and double-stranded and

153 issues upon association with C3b and surface polyanions such as sialic acids, heparin, and other glyc

154 ssed on myeloid cells 2 (TREM2), which binds polyanions, such as dextran sulphate and bacterial LPS,

155 A) and poly(dT), as well as non-nucleic acid polyanions, such as heparan sulfate proteoglycan.

156 lease II (EC 3.1.22.1), by glycosaminoglycan polyanions, such as heparin, chondroitin 4-sulfate, and

157 of the gp120 which is known to interact with polyanions, such as phosphorothioate oligodeoxynucleotid

158 It is demonstrated how a polyanion supporting electrolyte in concert with a conju

159 These activities can be inhibited by the polyanion suramin in a rapidly reversible manner.

160 Like DNA, SPS is a high-molecular-weight polyanion that is soluble in water but insoluble in alco

161 ure consists of isolated [CuB(4)O(10)](6)(-) polyanions that are bridged by six LiO(4) tetrahedra.

162 sulfate (OSCS) and other high charge-density polyanions that could potentially be used to adulterate

163 tron-accepting molecule inside the solid, a 'polyanion', that fills its available energy states with

164 Moreover, in the presence of a polyanion the fluorophore was far more resistant to quen

165 In the presence of species that bind these polyanions, the activity of the enzyme is regained in an

166 After conversion into polyanions, these four copolymers exhibited activity aga

167 Addition of a polyanion to these monomers at neutral pH fails to conve

168 buffer concentration, etc.) confirm that the polyanion unit (1-V2) itself is the dominant active cata

169 The polyanion unit in 1 is disorder-free.

170 pidly when added to culture media containing polyanions, whereas PC-containing complexes did not.

171 n in host tissues through its recognition of polyanions, which mediate CFH binding to host cell surfa

172 the nucleus in low-salt buffer using various polyanions, which mimic the phosphate backbone of DNA.

173 HBV capsid assembly and integrity depend on polyanions, which probably can help minimize intersubuni

174 ethylphosphonic acid ((M)MPA) product to the polyanions, which ultimately inhibits catalytic turnover

175 covalent AVP-pVIc complexes (AVP-pVIc) as a polyanion with a high negative charge density.

176 ter premixing a catechol-functionalized weak polyanion with a polycation in dimethyl sulphoxide (DMSO

177 The generation of gaseous polyanions with a Coulomb barrier has attracted attentio

178 ry DNA/PLL complexes by displacing DNA while polyanions with a longer carboxyl/backbone distance effe

179 Polyanions with a shorter carboxyl/backbone distance ten

180 rin) based on the strong binding reaction of polyanions with protamine.