ライフサイエンスコーパス: polyclonal

1 While the response was markedly polyclonal, 88% of clones failed to recognize clade 6B v

2 The rabbit polyclonal Ab responses (i) were successfully focused on

3 -doublecortin antibodies, such as the rabbit polyclonal Abcam 18732, are widely used as neurogenesis

4 Polyclonal Abs isolated from HIV-infected subjects also

5 different, as shown using specific mAbs and polyclonal Abs made against Patr-AL.

6 In contrast, polyclonal activation of endogenous memory-like I-A(12%)

7 , IL-5, and IFN-gamma in response to OVA and polyclonal activation.

8 gle-cell basis the affinity and frequency of polyclonal Ag-specific T cells directly ex vivo, we demo

9 but also mismatches in HLA-DRB3 may induce a polyclonal allo-immune response associated with conversi

10 Polyclonal and Ag-specific Treg accumulation in the skin

11 T cell proliferation in the settings of both polyclonal and allospecific stimulation.

12 iferation, and cytokine production following polyclonal and antigen-specific stimulation.

13 g, because similar kinetics were observed in polyclonal and antigen-specific transgenic contexts.

14 nces showed that these responding cells were polyclonal and encompassed a broad range of structural T

15 ing new insights: (i) Barrett's esophagus is polyclonal and highly mutated even in the absence of dys

16 ESR1 mutations are often polyclonal and longitudinal analysis shows distinct clon

17 notypes, subtypes, and variants to serum and polyclonal and monoclonal antibodies isolated from patie

18 he native conformation of HA recognizable by polyclonal and monoclonal antibodies.

19 igate the role of IL-10 during conditions of polyclonal and neoplastic plasmacytosis for the regulati

20 ells were analyzed with flow cytometry after polyclonal and pathogen-specific stimulation (with varic

21 -uracil riboflavin precursor and to activate polyclonal and quasi-monoclonal mouse MAIT cells.

22 GFP(+)Tfh cells were found to be polyclonal and related to GFP(-)Tfh cells of Peyer's Pat

23 theless, T-cell receptor rearrangements were polyclonal and showed a diverse repertoire, demonstratin

24 involved in regulating negative selection of polyclonal and T cell receptor (TCR) transgenic thymocyt

25 ing Bhlhe40 reporter mice and analyzing both polyclonal and TCR transgenic Th cells, we found that Bh

26 Using a series of polyclonal and transgenic self-reactive models harboring

27 e evolved antigenic sites effectively evades polyclonal anti-AAV1 neutralizing sera from immunized mi

28 In addition, affinity-purified polyclonal anti-AD-5 antibodies prepared from individual

29 These data demonstrate that endogenous polyclonal anti-cytokine antibody responses can enhance

30 fetus and newborn is highly effective using polyclonal anti-D, a recombinant alternative is long ove

31 resulting surfaces were used to investigate polyclonal anti-diclofenac antibodies recognition and re

32 sive immunization of DENV-infected mice with polyclonal anti-DJ NS1 Abs reduced viral Ag expression a

33 ELISA using polyclonal anti-HCP antibodies as reagents for capture,

34 is by monocytes, inhibit binding of maternal polyclonal anti-HPA-1a Abs, and weakly inhibit aggregati

35 A polyclonal anti-human EGFR Ab was conjugated to citrate-

36 immobilization of a coating antibody (Ab), a polyclonal anti-IgG, onto a treated PDMS surface.

37 1beta during an immune response could elicit polyclonal anti-IL-1beta antibody responses that modulat

38 The resulting polyclonal anti-IL-1beta antibody responses were assesse

39 Polyclonal anti-immunoglobulin G (anti-IgG) secondary an

40 ay be critical to the mechanism of action of polyclonal anti-KEL immunoprophylaxis.

41 Whereas polyclonal anti-KEL sera completely prevented alloimmuni

42 murine model in which immunoprophylaxis with polyclonal anti-KEL sera prevents alloimmunization in wi

43 ond electrode is surface-functionalized with polyclonal anti-M1 antibodies, which then serve to ident

44 quently incubated with a fluorophore-labeled polyclonal anti-peroxidase antibody (anti-HRP-Alexa Fluo

45 ant SasX or passive immunization with rabbit polyclonal anti-SasX IgG significantly decreased the siz

46 A rabbit polyclonal anti-sPLA2-X antibody identified sPLA2-X by W

47 ma screening for those patients treated with polyclonal anti-T-cell induction.

48 12), monoclonal antibodies (aIRR = 1.83), or polyclonal antibodies (aIRR = 2.03); in recipients who w

49 Human polyclonal antibodies (PAbs) are ideal, but this is depe

50 on commercial ELISA kits which are based on polyclonal antibodies (pAbs) not previously tested for c

51 ls after the addition of either RSV-specific polyclonal antibodies (PAbs) or RSV glycoprotein-specifi

52 mining the reactivity of plasmablast-derived polyclonal antibodies (PPAbs) to influenza proteins.

53 Fully human polyclonal antibodies against EBOV were purified and eva

54 Biotinylated polyclonal antibodies against Escherichia coli were immo

55 Rabbit polyclonal antibodies and commercially available mouse m

56 s method utilizes oligonucleotide-conjugated polyclonal antibodies and quantifies antibody-antigen bi

57 Conventional monoclonal and polyclonal antibodies are sensitive to changes in enviro

58 In conclusion, these data show that polyclonal antibodies are superior to monoclonal antibod

59 RNA immunoprecipitation assays) using m(6)A polyclonal antibodies coupled with mRNA isolation, quant

60 viral protein 40 antigen was used to derive polyclonal antibodies for RDT and enzyme-linked immunoso

61 orthogonal alkyne handle into monoclonal or polyclonal antibodies from different species in an Fc-sp

62 uthentic virus from infected individuals and polyclonal antibodies from vaccinees.

63 Polyclonal antibodies generated in goats were superior r

64 using the conventional Ricin monoclonal and polyclonal antibodies have also been demonstrated for co

65 amplified via liposomes; (ii) the use of two polyclonal antibodies in the sandwich assay format incre

66 Immunochemical staining with polyclonal antibodies showed that the addition of deterg

67 standard membrane-feeding assays, anti-FREP1 polyclonal antibodies significantly blocked transmission

68 ination in the amount and the avidity of the polyclonal antibodies specific for the HA1 subunit of th

69 the R5, G12 and Skerritt monoclonal and two polyclonal antibodies to well-defined gluten protein typ

70 Polyclonal antibodies were generated against OTC molecul

71 ned monoclonal (outer surface protein A) and polyclonal antibodies were performed on all tissue secti

72 iously, we have demonstrated that B virus gD polyclonal antibodies were unable to neutralize B virus

73 immunoassays (with the use of monoclonal or polyclonal antibodies), parathyroid hormone, and albumin

74 Polyclonal antibodies, derived from humans or hyperimmun

75 and immunohistochemistry detection by HSV-1 polyclonal antibodies, showed a lack of viral proteins i

76 solate distinct OCBs against a background of polyclonal antibodies.

77 nse and produced high titers of high avidity polyclonal antibodies.

78 ere used to derive a panel of monoclonal and polyclonal antibodies.

79 th native-OVA specific monoclonal as well as polyclonal antibodies.

80 dioimmunohistochemistry analysis using P2X7R polyclonal antibodies.

81 g synthesised and used for the production of polyclonal antibodies.

82 pentanoic acid-BSA (SA2-BSA) antigens toward polyclonal antibody (Ab-155).

83 EqCXCL16 or by pretreatment with guinea pig polyclonal antibody against EqCXCL16 protein (Gp anti-Eq

84 A rabbit polyclonal antibody against one of the same epitopes com

85 s were screened by measuring binding to IgG (polyclonal antibody against peanut allergen) and IgE (se

86 emical staining of paraffin sections using a polyclonal antibody against the protein LIN28A, and (3)

87 using sandwich assay by utilising the rabbit polyclonal antibody as the capture antibody and conjugat

88 absence of NK cells, because treatment with polyclonal antibody asialogangloside GM-1 did not augmen

89 when measured by the monoclonal but not the polyclonal antibody immunoassay.

90 following transplantation and increased with polyclonal antibody induction therapy (IRR=1.65, 95% CI

91 ed for sex, age, transplant year, and use of polyclonal antibody induction.

92 derived from the antigen-binding domains of polyclonal antibody mixtures.

93 MAF-1 fusion protein was used to produce the polyclonal antibody of rat.

94 ylactic or therapeutic administration of the polyclonal antibody preparations (TcPAbs) can protect mi

95 An anti-outer membrane protein A (OmpA) polyclonal antibody previously produced (in our laborato

96 as well as resistance to neutralization by a polyclonal antibody raised against the wild-type virus.

97 SSTI with USA300, despite eliciting a strong polyclonal antibody response against antigens whose expr

98 has been confounded by the complexity of the polyclonal antibody response in humans.

99 we found that S. aureus SSTI elicited broad polyclonal antibody responses in both BALB/c and C57BL/6

100 Mapping polyclonal antibody responses to infectious diseases to

101 o assess the quality of immunization-induced polyclonal antibody responses.

102 Immunohistochemistry with a custom polyclonal antibody showed staining localized to the inn

103 the results of anatomical studies using our polyclonal antibody specifically against human melanopsi

104 A polyclonal antibody that targets the beta-subunit of the

105 An ovine polyclonal antibody therapy has been developed against E

106 iple inflammatory conditions, and anti-HMGB1 polyclonal antibody treatment improves survival in a mod

107 sor chip was used to immobilise alpha-casein-polyclonal antibody using EDC/NHS coupling procedure.

108 a positive correlation with the anti-cod PAV polyclonal antibody, but no correlation with the anti-ca

109 search on novel approaches to produce potent polyclonal antibody-based therapies have been deficient.

110 ntracellular ZIKV NS3, using a ZIKV-specific polyclonal antibody.

111 ulated that a bolus of enhanced IL-21-primed polyclonal antigen-specific CTL combined with CTLA4 bloc

112 e production in response to stimulation with polyclonal antigens or TAA.

113 Polyclonal antihuman thymocyte rabbit IgGs (antithymocyt

114 purified preparations of the resultant human polyclonal antisera against low- and high-dose VEEV chal

115 iruses with RBS deletions are able to escape polyclonal antiserum binding and are able to infect and

116 To improve this strategy using a polyclonal approach, we developed a vaccine targeting VE

117 e to developmental landmarks and revealing a polyclonal architecture of the human cerebral cortex.

118 Early polyclonal ASC expansion, GC formation, and virus-specif

119 ng blood samples (r = 0.53 and P = 0.008 for polyclonal assay; r = 0.54 and P = 0.004 for monoclonal

120 erval on chromosome 4 display high titers of polyclonal autoantibodies with generalized B cell hypera

121 e sought to investigate the possibility of a polyclonal autoimmune event in the airways of asthmatic

122 We report a "polyclonal" autoimmune event occurring in the airways of

123 d by iNKT cells, because similarly activated polyclonal autologous T cells did not have this effect.

124 pulation of Tregs that cannot fully suppress polyclonal autoreactive T cells.

125 In infected mice and NHP, polyclonal B cell activation and autoantigens secretion

126 otein A (SpA), a surface protein that drives polyclonal B cell expansion and induces cell death in th

127 ly abused prescription opioid oxycodone, the polyclonal B cell population specific for an oxycodone-b

128 i-PAR2 antibodies, the monoclonal SAM-11 and polyclonal B5, inhibited AHR, airway eosinophilia, the i

129 Polyclonal Bim(-/-) and Bim(-/-)Nur77(-/-) mice exhibite

130 ileukemia activity of adoptively transferred polyclonal cancer antigen-reactive T cells deficient in

131 teristic circulating activated monocytes and polyclonal CD10(+) B cells.

132 specificity plays in the partitioning of the polyclonal CD4 T cell repertoire between Tfh and NonTfh

133 Thus, we conclude that in a polyclonal CD4 T cell repertoire, features of TcR-peptid

134 A dominant polyclonal CD4 T cell response against patient's mismatc

135 owever, in vivo effects of A2aR signaling on polyclonal CD4 T cells during a primary response to fore

136 sis for this anatomic preference by tracking polyclonal CD4(+) T cells specific for an MHC class II-b

137 Here we studied polyclonal CD4(+) T cells specific for green fluorescent

138 ntial allogeneic immune synapse formation in polyclonal CD4(+) T cells using high-throughput imaging

139 Thus, the immunotolerance of polyclonal CD4(+) T cells was maintained by distinct mec

140 naturally occurring subpopulation of anergic polyclonal CD4(+) T cells, enriched for self antigen-spe

141 spectrum of helminth-induced effects on the polyclonal CD8 T response, indicating the lack of requir

142 o a stable marker of priming affinity within polyclonal CD8(+) T cell populations.

143 on, because its development required non-TS1 polyclonal CD8(+) T cells.

144 We identified a polyclonal CD8+ T-cell response against mutant KRAS G12D

145 enhanced IFN-gamma production compared with polyclonal cells, protected immune-deficient mice agains

146 The polyclonal character of commercial antivenoms, obtained

147 that patient-derived xenografts were highly polyclonal, consisting of tens to hundreds of LPC clones

148 nding antibodies perform optimally when in a polyclonal context and that the targeted elicitation of

149 hanced by several orders of magnitude in the polyclonal context.

150 erties of broadly neutralizing antibodies in polyclonal contexts will be essential for guiding design

151 e biological activity of these antibodies in polyclonal contexts, comparing both IgG and IgA isotypes

152 This expeditiously yielded polyclonal CTL lines uniformly expressing markers associ

153 currently used in clinical trials are either polyclonal, donor- or antigen-specific.

154 that, when TnBVank1 was stably expressed in polyclonal Drosophila S2 cells, apoptosis is induced.

155 of starting population) clones to moderate, polyclonal engraftment.

156 fluoresceinated IgG constant H chain-binding polyclonal F(ab')2 (IgHPolyFab) is used as the fluoresce

157 ified as a result of the binding of multiple polyclonal Fabs to the C region of primary IgH.

158 mechanisms to transiently stimulate a broad, polyclonal germinal center reaction, an inherently mutag

159 strain, resistant to neutralization by both polyclonal-HCV-infected plasma and multiple broadly neut

160 Polyclonal HEL antibodies dramatically inhibited the ant

161 Cases with polyclonal hematopoiesis might represent hereditary diso

162 ining patients, 4 presented a clonal and 7 a polyclonal hematopoiesis, suggesting that certain triple

163 erm line JAK2 mutations were associated with polyclonal hereditary thrombocytosis and triple-negative

164 displayed fitness comparable to that of the polyclonal high-titer adapted virus.

165 because of the difficulties of working with polyclonal human antibodies usually available only in sm

166 gen-specific highly neutralizing therapeutic polyclonal human antibody (TcPAb) preparations in 6 mont

167 in the alpha1KI mouse model, which produces polyclonal human IgA1 prone to mesangial deposition.

168 Here, we established an immortalized polyclonal human parietal epithelial cell (hPEC) line fr

169 Reactive T cells were polyclonal (ie, they expressed CD4 and CD8), T-helper ty

170 nce of the three binders, allergic patients' polyclonal IgE reacted with Phl p 1, indicating high-den

171 Anti-TYKW mutant polyclonal IgG antibodies competitively inhibited bindin

172 Moreover, polyclonal IgG or monoclonal IgG1 added to IgG-depleted

173 , we measured increasing affinity of macaque polyclonal IgG responses over the course of the immuniza

174 Preincubation of polyclonal IgG with CD64-IgE Fc established allergen-spe

175 e influenza pandemic of 2009 in pooled human polyclonal IgG.

176 ding to galactosylated Fc fragments in human polyclonal IgG.

177 Treatment with rabbit polyclonal IgGs in the absence of additional immunosuppr

178 om wild-type mice, as well as by engineering polyclonal Ighgamma1/gamma1 and Ighepsilon/epsilon mice,

179 Polyclonal IgM rescued B cell development and returned a

180 that separate the effects of CSR and SHM on polyclonal immune responses.

181 resistance to in vitro neutralization by MV polyclonal immune sera without altering its thermostabil

182 We show that the UK outbreak was polyclonal in nature, caused by multiple distinct but cl

183 Polyclonal induction was associated with increased melan

184 However, whole-genome sequencing suggests a polyclonal infection.

185 e haplotypes comprising as little as 2% of a polyclonal infection.

186 identifying amplifications in 13 additional, polyclonal infections.

187 ependent effector functions are regulated by polyclonal influenza virus-binding antibody mixtures in

188 munogenic and cross-reactive with MOG at the polyclonal level, it fails to expand a threshold level o

189 has not been extensively investigated at the polyclonal level.

190 nd low-avidity cells sorted from a severe HA polyclonal line revealed that 94% of the high-avidity ce

191 Multiple T-cell clones and polyclonal lines having different avidities for the pept

192 itis, inflammatory arthropathy, intermittent polyclonal lymphoproliferation, and significant chronic

193 oliferation, and effector differentiation of polyclonal memory CD8(+) T cells after infection with wi

194 uing observations raise the question: How do polyclonal metastases emerge from the primary tumor?

195 Limitations of these analyses include a polyclonal method of ApoE measurement, rather than isofo

196 tween very similar antibodies present within polyclonal mixtures.

197 Using this tool, we characterized polyclonal mouse MAITs as memory (CD44+) CD4-CD8lo/neg T

198 Here we develop a polyclonal mouse model of breast tumour heterogeneity, a

199 CD34(+) cell products are capable of stable, polyclonal multilineage reconstitution with follow-up of

200 retreated bone marrow-derived DC (BMDC) with polyclonal murine or human IgM prior to LPS activation a

201 By treating glioma cell lines with the polyclonal N-20 antibody against surface-localized GRP78

202 us infection, Apobec3/Rfv3 promotes a potent polyclonal NAb response.

203 ouse model (EF4.1) expressing a limited, yet polyclonal naive T-cell repertoire was used.

204 The polyclonal nature infections in high transmission settin

205 Clonal tracking techniques confirmed the polyclonal nature of CNS-infiltrating cells, with multip

206 The apparent polyclonal nature of the isolates suggests de novo emerg

207 l now, but the reliability, pan-specificity, polyclonal nature, and stability of the available pan-sp

208 bstitution in E that significantly increased polyclonal neutralization but nonetheless were successfu

209 PBMC or polyclonal NK cells isolated from normal donors served a

210 t lysis of articular chondrocytes by PBMC or polyclonal NK cells was potentiated by stimulation with

211 city to produce Th1 cytokines in response to polyclonal or Ag-specific stimuli.

212 ated and significantly more suppressive than polyclonal or DeltaCAR Tregs in the presence of HLA-A2,

213 grade or high-grade metastasizing neoplasms, polyclonal or monoclonal lymphoproliferative disorders,

214 and CD8+ T cell proliferation in response to polyclonal or SIV-specific stimulation.

215 gainst BRCA deficiencies in cancer cells and polyclonal patient-derived xenograft models, including t

216 myeloid BM cells (59% vs 22%; P = .03) and a polyclonal pattern of inactivation of the X-chromosome o

217 GUS also suggest the possible existence of a polyclonal phase preceding the development of MGUS.

218 ferring resistance to neutralization by both polyclonal plasma and broadly neutralizing monoclonal an

219 ed reprogramming and the pooled selection of polyclonal pluripotent cells results in high-quality, st

220 s, granulocytes, B cells, and T cells from a polyclonal pool of hematopoietic stem and progenitor cel

221 ere was rapid engraftment and expansion of a polyclonal pool of transgene-positive functional T cells

222 expression of Nur77GFP and OX40 identifies a polyclonal population of high-affinity tumor-associated

223 T cells increased following infection in the polyclonal populations, suggesting an increase in pathog

224 en screening for pathogenic effectors within polyclonal populations, Tregs should be removed from the

225 thought to be present within the cells of a polyclonal premalignant lesion and the features that und

226 xpress reserve ISC genes) via multifocal and polyclonal processes.

227 ae was expressed and purified and raising of polyclonal rabbit anti-OmpW was done.

228 Polyclonal rabbit antisera were screened against the coa

229 AAVs, specifically, to obtain a picture of "polyclonal" reactivity as is the situation in humans.

230 s, it is unclear that all naive cells from a polyclonal repertoire have memory cell potential.

231 ed with the ability to phenotype a patient's polyclonal repertoire in the same analysis further shows

232 in-resident memory T cells that arise from a polyclonal repertoire of cells induced by infection with

233 ncy of anti-insulin B lymphocytes within the polyclonal repertoire of VH125Tg/NOD mice, suggesting en

234 hat are naturally responding and represent a polyclonal repertoire.

235 ligoclonal population versus being part of a polyclonal repertoire.

236 ss-reactivity with MOG-specific T cells, the polyclonal response to NFM15-35 did not expand threshold

237 e subregion of Env, consistent with a highly polyclonal response.

238 inity, MOG-specific T cells that defined the polyclonal response.

239 BVANK1 and Alix proteins in the cytoplasm of polyclonal S2 cells.

240 lticolor lineage tracing to demonstrate that polyclonal seeding by cell clusters is a frequent mechan

241 ght definitive evidence for the existence of polyclonal seeding in human malignancy and to establish

242 In the second patient, we observed polyclonal seeding, in which two independent clones seed

243 DS-PAGE and immunoassay analysis with rabbit polyclonal sera and human IgE indicated only minor diffe

244 as standardized reagents to monitor complex polyclonal sera for neutralization activity and to chara

245 The polyclonal sera of the three donors also reflect this pr

246 on of antibodies of unknown concentration in polyclonal sera.

247 uated the anti-HIV Ab effector activities in polyclonal serum samples from HIV-infected donors, VAX00

248 howed a more similar response profile across polyclonal serum samples.

249 Polyclonal serum was verified for strong Zika virus-neut

250 d a rapid, sensitive, and robust method, the polyclonal serum-based proximity ligation assay (polyPLA

251 rol and efficient gene disruption, even in a polyclonal setting.

252 Moreover, polyclonal splenocytes from nonobese diabetic (NOD) mice

253 itoneal sites, and two patients demonstrated polyclonal spread and reseeding.

254 -gamma unresponsive even after TCR-dependent polyclonal stimulation (anti-CD3 plus anti-CD28) but pro

255 8) but produced IFN-gamma by TCR-independent polyclonal stimulation (phorbol 12-myristate 13-acetate

256 d activation by CD4(+) and CD8(+) T cells on polyclonal stimulation, and displayed lower major histoc

257 tive responses to alloantigen, as well as to polyclonal stimulation, than did their CD244(-) counterp

258 y reduced and hyporesponsive to cytokine and polyclonal stimulation.

259 an naive CD4 T-cell expansion in response to polyclonal stimuli by inducing their apoptosis and promo

260 lated in vitro with CT, mmCT, or dmLT plus a polyclonal stimulus (staphylococcal enterotoxin B) or sp

261 ome (TSS), bacterial superantigens trigger a polyclonal T -cell response leading to a potentially cat

262 splenocytes or human PBMCs was elevated upon polyclonal T cell activation, and this was reduced by mi

263 phospholipids within human skin in vivo, and polyclonal T cell responses are dependent on CD1a protei

264 -containing multimers of naturally occurring polyclonal T cell responses, which represents a strong a

265 but fails to induce demyelinating disease by polyclonal T cells despite having the same TCR contact r

266 CD8(+) T cells and in fibrosarcoma-reactive polyclonal T cells enhanced the persistence of PD-1 gene

267 We found that c-MPL(+) polyclonal T cells expand and proliferate in response to

268 The reduced diabetes transfer efficiency by polyclonal T cells in NSG recipients was associated with

269 ane-induced arthritis (PIA) in the rat where polyclonal T cells induce chronic arthritis after being

270 itumor T cell responses, yet detecting these polyclonal T cells is challenging.

271 minority of Reed-Sternberg cells and by most polyclonal T cells rosetting around Reed-Sternberg cells

272 pecific antibody (bsAb) that redirects human polyclonal T cells to AC133(+) GBM stem cells (GBM-SC),

273 Thus, these DARTs redirected polyclonal T cells to specifically engage with and kill

274 to express synthetic receptors that redirect polyclonal T cells to surface antigens for subsequent tu

275 ucible inactivation of Dicer1 in early stage polyclonal T-ALL cells was sufficient to abrogate T-ALL

276 ells, thereby inducing target cell-dependent polyclonal T-cell activation and proliferation, and lead

277 While AD harbors a highly polyclonal T-cell receptor repertoire, and despite the l

278 sidue Glu(3) have a broad negative impact on polyclonal T-cell responses.

279 ncrease in IL-17A (P = .03) production after polyclonal T-cell stimulation, and an enhanced IL-10 res

280 lesional and nonlesional AD showed a highly polyclonal TCR pattern, without evidence of oligoclonal

281 elf-reactive response has not only a diverse polyclonal TCR repertoire, but also comprises a broad ra

282 Biotinylated rabbit polyclonal to chick IgY (rIgPxcIgY) and phosphorylthioat

283 resulting Ran-SPION-rIgPxcIgY carries chick polyclonal to microtubule-associated protein 2 (MAP2) as

284 s clonotype and had negligible impact on the polyclonal Treg cell repertoire.

285 ed normal suppressive function in peripheral polyclonal Treg cells from patients with celiac disease,

286 We show that polyclonal Treg cells suppressed uveitis in mice as effi

287 sisting of in situ injection of preactivated polyclonal Treg cells that would exert bystander suppres

288 y reduced suppressive function compared with polyclonal Treg cells.

289 However, polyclonal Tregs are nonspecific and therefore could pot

290 However, the affinity of naturally occurring polyclonal Tregs for any self-antigen, let alone MOG, ha

291 We used CAR technology to redirect human polyclonal Tregs toward donor-MHC class I molecules, whi

292 d a model where the TCR repertoire of normal polyclonal Tregs was limited by serial transfers into IL

293 Emerging data indicate that, compared with polyclonal Tregs, disease-relevant antigen-specific Treg

294 t of graft-versus-host disease compared with polyclonal Tregs.

295 protection from graft rejection compared to polyclonal Tregs.

296 lood mononuclear cells more effectively than polyclonal Tregs.

297 man primates and humans points to a role for polyclonal vaccine-induced antibody responses in protect

298 Using mixed adoptive transfers of polyclonal wild-type and CD40-deficient CD8(+) T cells i

299 s (91 of 360), of whom 28.6% (26 of 91) were polyclonal, with mutations associated with acquired resi

300 s (63 of 161), of whom 49.1% (27 of 55) were polyclonal, with rates of mutation detection unaffected