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1 dering their intrinsically promising role in polygenic disease.
2 Asthma is a complex polygenic disease.
3 Type 1 diabetes is a common polygenic disease.
4 M) reported in 1994 was the first in a human polygenic disease.
5 may alter Treg cell function contributing to polygenic disease.
6 netic factors and is associated with several polygenic diseases.
7 r both simple monogenic diseases and complex polygenic diseases.
8 y associated with targeting a single gene in polygenic diseases.
9 rstand the complex nature of these and other polygenic diseases.
10 ajor hopes for the future are application to polygenic diseases.
13 proach can enrich mutations underlying these polygenic diseases among the top of candidate mutations.
14 ymorphisms will enhance the investigation of polygenic diseases and the use of genetics in drug devel
16 or schizophrenia, we infer an overwhelmingly polygenic disease architecture in which >/=71% of 1-Mb g
17 If validated, GMAS may imply that common polygenic diseases are related as much to group interact
18 e for single-gene disorders, whereas complex polygenic diseases are typically due to multiple genetic
19 t predictor of health status in many chronic polygenic diseases, but its role in CF has not been syst
22 dating the genetic predisposition for common polygenic diseases, especially in determining the functi
23 date-gene approach in association studies of polygenic diseases has often yielded conflicting results
24 alized vitiligo is a common, multifactorial, polygenic disease in which autoimmune loss of melanocyte
25 zed vitiligo is an acquired, multifactorial, polygenic disease in which depigmented spots of skin, ov
26 ing has been performed in a variety of human polygenic diseases, including schizophrenia, bipolar aff
27 ch to the identification of genes underlying polygenic disease is to identify "functional candidates"
28 An important approach to the study of such polygenic diseases is the use of appropriate animal mode
29 enetic extremes of rare monogenic and common polygenic diseases lie diverse oligogenic disorders invo
32 promising for repositioning drugs for use in polygenic diseases such as PD, and is capable of address
33 roader potential that also includes acquired polygenic diseases, such as congestive heart failure.
34 ute to the development of type 2 diabetes, a polygenic disease that is characterized by insulin resis
35 e BioBreeding diabetes-prone (BBDP) rat is a polygenic disease that resembles in many aspects human t
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