ライフサイエンスコーパス: polymerase

1 is responsible for the interaction with RNA polymerase.

2 esent the crystal structure of the Mtb DnaE1 polymerase.

3 hat affect the RNA-binding properties of the polymerase.

4 utilizes a thermostable mutant of the phi29 polymerase.

5 of ribonucleotides incorporated by the mtDNA polymerase.

6 affects replication by bacteriophage T7 DNA polymerase.

7 initiation complex for the hepatitis C virus polymerase.

8 art of csc, encoding the serogroup C capsule polymerase.

9 nfluence the enzymatic properties of the DNA polymerase.

10 uced nucleosome intermediates using only RNA Polymerase.

11 of non-fluorescent native nucleotides by DNA polymerases.

12 ynthesis resembling those of replicative DNA polymerases.

13 pools that compete for recruitment by viral polymerases.

14 ally studied for its role in stimulating DNA polymerases.

15 rs that are elongated by the replicative DNA polymerases.

16 DNA synthesis, acting as a sliding clamp for polymerases.

17 , and GII.17, four of which harbored GII.P16 polymerases.

18 itive supercoils between head-on-conflicting polymerases.

19 tion) is mainly catalysed by poly-ADP-ribose polymerase 1 (PARP1), whose role in gene transcription m

20 e found that transcription initiation by RNA polymerase 2 resulted in confinement of the mRNA-produci

21 tnangien, gladiolin was found to inhibit RNA polymerase, a validated drug target in M. tuberculosis.

22 de and profile the enzymatic activity of RNA polymerase across various loci and following experimenta

23 screen in Saccharomyces cerevisiae using DNA polymerase active-site mutants as a "sensitized mutator

24 odels that can both deconvolve the stages of polymerase activity and identify significant changes in

25 everse transcriptase (RT) possesses both DNA polymerase activity and RNase H activity that act in con

26 the IAV polymerase complex, thereby limiting polymerase activity and subsequent viral replication.

27 ngly, we also found that TRIM6 enhances EBOV polymerase activity in a minigenome assay and TRIM6 knoc

28 RNA polymerase activity is regulated by nascent RNA sequence

29 ciferase minigenome assay, we quantified the polymerase activity of all possible 16 ribonucleoprotein

30 We link error-prone DNA polymerase activity to the generation of variants.

31 y fully supported Msps-dependent microtubule polymerase activity.

32 ch relies on the target enzyme-triggered DNA polymerase activity.

33 urce of information on the regulation of RNA polymerase activity.

34 ing-strand DNA synthesis by facilitating DNA polymerase alpha function at replication forks.

35 However, only PrimPol, DNA polymerase alpha, telomerase, and the mitochondrial huma

36 d expression of the catalytic subunit of DNA polymerase alpha.

37 eic acid processing enzymes, including a DNA polymerase, an RNA polymerase and a DNA ligase, to use F

38 enzymes, including a DNA polymerase, an RNA polymerase and a DNA ligase, to use Fe2+ in place of Mg2

39 GreA restarts backtracked RNA polymerase and hence promotes transcription fidelity.

40 nal detection of the viral DNA-dependent RNA polymerase and intermediate and late transcription facto

41 RNA polymerase and ribosomes form a one-to-one complex with

42 This direct interaction between RNA polymerase and ribosomes may contribute to the coupling

43 ation that maps to the gene encoding the VP1 polymerase and shows diminished growth and RNA synthesis

44 -mediated slippage may be exhibited by other polymerases and enrich gene expression.

45 governed by the activities of various 3'-end polymerases and exonucleases.

46 age encodes its own primase, DNA ligase, DNA polymerase, and enzymes necessary to synthesize and inco

47 hich associates with the plastid-encoded RNA polymerase, and is essential for inducing the plastomic

48 Key residues in the polymerase are located in similar positions to those of

49 TLS polymerases are capable of bypassing a distorted templat

50 DNA polymerases are essential enzymes that faithfully and ef

51 High fidelity replicative DNA polymerases are unable to synthesize past DNA adducts th

52 resolution structural data revealed that the polymerase assembles into a central polymerase core and

53 nscription elongation factors (TEFs) such as polymerase-associated factor 1 (Paf1), but it is not kno

54 The polymerase-associated factor complex (PAFc) is an epigen

55 We propose that the configuration of DNA polymerases at stalled forks facilitates the resumption

56 (matrix protein 1 [M1], nucleoprotein [NP], polymerase basic protein 1 [PB1]).

57 recruitment of the repair proteins XRCC1 and polymerase beta at damaged telomeres, while the PARP1/2

58 DTPs were thought to target RNA polymerase, but conflicting observations leave the mecha

59 The idea that backtracked RNA polymerase can stimulate recombination presents a DNA tr

60 DNA polymerases catalyze a metal-dependent nucleotidyl trans

61 Digital polymerase chain reaction (dPCR) end point platforms dir

62 -rich protein 2-based RDTs using qualitative polymerase chain reaction (PCR) (nested PCR targeting th

63 chinella serology on patient sera as well as polymerase chain reaction (PCR) and larval identificatio

64 Polymerase chain reaction (PCR) and other molecular assa

65 Quantitative polymerase chain reaction (PCR) and reverse-transcriptio

66 lar probing technologies involving real-time polymerase chain reaction (PCR) assays that facilitate d

67 ZIKV-RNA load was quantified by polymerase chain reaction (PCR) cycles in blood/ urine.

68 Detection of pneumococcus by lytA polymerase chain reaction (PCR) in blood had poor diagno

69 erial pathogen detection by both culture and polymerase chain reaction (PCR) in children.

70 Routine polymerase chain reaction (PCR) ribotyping and multiple-

71 spleen was not palpable, and a quantitative polymerase chain reaction (PCR) test for JAK2/V617F was

72 RNA sequencing (RNA-seq) and real-time polymerase chain reaction (PCR) were used to examine tra

73 DNA-based techniques such as polymerase chain reaction (PCR), real time PCR (RT-PCR)

74 d blood leukocytes was used for quantitative polymerase chain reaction (PCR), RNA sequencing, and com

75 atically improved by use of real-time immuno-polymerase chain reaction (PCR), to parasitemia limits o

76 pots defined based on parasite prevalence by polymerase chain reaction (PCR)- and the prevalence of a

77 ients with HCoV detected in nasal samples by polymerase chain reaction (PCR).

78 leic acid in plasma by NGMS and quantitative polymerase chain reaction (PCR).

79 asured by quantitative reverse transcription polymerase chain reaction (PCR).

80 asites by quantitative reverse transcription polymerase chain reaction (PCR).

81 ose based on culture and colony-counting and polymerase chain reaction (PCR).

82 e also measured using quantitative real-time polymerase chain reaction (Q-RT-PCR).

83 urements (acetylene block), and quantitative polymerase chain reaction (qPCR) of functional genes in

84 Quantitative reverse transcription polymerase chain reaction (qRT-PCR) amplification of miR

85 was confirmed by urine reverse-transcription polymerase chain reaction (RT-PCR) analysis in 17 cases

86 sting was negative and reverse-transcription polymerase chain reaction (RT-PCR) testing was not perfo

87 luorescence, real-time reverse-transcription polymerase chain reaction (RT-PCR), and quantitative RT-

88 utive children aged <18 years with real-time polymerase chain reaction (RT-PCR)-confirmed EVD were en

89 ization of Giardia isolates was performed by polymerase chain reaction amplification of a fragment of

90 ymphocytes and CLN3 transcript analysis with polymerase chain reaction amplification were performed i

91 d chromatin immunoprecipitation quantitative polymerase chain reaction analyses in Huh-7 cells.

92 We used immunohistochemical and quantitative polymerase chain reaction analyses to examine expression

93 MRD was evaluated by polymerase chain reaction analysis of Ig/TCR gene rearra

94 ion density was calculated with quantitative polymerase chain reaction analysis of nasopharyngeal/oro

95 n expression were analyzed with quantitative polymerase chain reaction and immunoblotting, respective

96 stem-loop reverse-transcriptase quantitative polymerase chain reaction and mRNA microarray, respectiv

97 16S rRNA genes was measured by Quantitative Polymerase Chain Reaction and no apparent differences we

98 Reverse transcription polymerase chain reaction and transcriptome analyses sug

99 V-D68 using real-time reverse- transcription polymerase chain reaction assay.

100 and vaginal swab specimens were evaluated by polymerase chain reaction followed by type-specific hybr

101 nia were tested using quantitative real-time polymerase chain reaction for 17 viruses.

102 maxillary molars were subjected to real-time polymerase chain reaction for assessment of osteoprotegr

103 METHODS AND We measured LTL by quantitative polymerase chain reaction in 566 outpatients (age: 63+/-

104 antitated by real-time reverse transcription-polymerase chain reaction in C cases presenting between

105 ion was assessed by using Cre-reporter mice, polymerase chain reaction of genomic DNA, and quantitati

106 Using a quantitative reverse transcription polymerase chain reaction platform, we analyzed miRNA ex

107 dex, fluorescence in situ hybridization, and polymerase chain reaction screening for relevant abnorma

108 t clinicians should consider IgM antibody or polymerase chain reaction testing for Zika virus as well

109 We performed multiplexed droplet digital polymerase chain reaction to detect spontaneous Kras mut

110 We used immunoblot and quantitative polymerase chain reaction to evaluate the molecular resp

111 Quantitative polymerase chain reaction was performed on the tissue sp

112 In this study, BRAF(V600E) allele-specific polymerase chain reaction was used to map the neoplastic

113 blotting, quantitative reverse-transcription polymerase chain reaction, and cell death assays.

114 tified by quantitative reverse transcriptase-polymerase chain reaction, and DNA methylation was quant

115 using flow cytometry, reverse-transcription polymerase chain reaction, and enzyme-linked immunoassay

116 chemical, quantitative reverse transcription polymerase chain reaction, and flow cytometry analyses.

117 stochemistry, luciferase activity, real-time polymerase chain reaction, and multiplex assays.

118 ning, flow cytometry, quantitative real-time polymerase chain reaction, and reciprocal bone marrow tr

119 ession-by quantitative reverse transcription polymerase chain reaction, flow cytometry, and Western b

120 rporate nucleic acid-based assays, including polymerase chain reaction, isothermal amplification, lig

121 alyzed by reverse transcription-quantitative polymerase chain reaction, to check for concordance with

122 METHODS AND By reverse transcription polymerase chain reaction, we evaluated gene expression

123 Quantitative reverse transcriptase-polymerase chain reaction, Western blot, and immunohisto

124 these questions, we developed a quantitative polymerase chain reaction-based approach to determine th

125 f p57 expression by immunohistochemistry and polymerase chain reaction-based DNA genotyping have emer

126 ssessment techniques, like flow cytometry or polymerase chain reaction-based methods, has been challe

127 cific oligonucleotide real-time quantitative polymerase chain reaction.

128 zed using Gut Low-Density Array quantitative polymerase chain reaction.

129 al methanogens were measured by quantitative polymerase chain reaction.

130 sured with the use of quantitative real-time polymerase chain reaction.

131 virus by quantitative reverse-transcription polymerase chain reaction.

132 nza virus by real-time reverse-transcription polymerase chain reaction.

133 9 years admitted with influenza confirmed by polymerase chain reaction.

134 in tumor tissue, determined by quantitative polymerase chain reaction.

135 or HBoV mRNA and genomic DNA by quantitative polymerase chain reaction.

136 monitored for ocular chlamydial infection by polymerase chain reaction.

137 munohistochemistry, histology, and real-time polymerase chain reaction.

138 tion were analyzed by real-time quantitative polymerase chain reaction.

139 pesviruses (HHVs) were measured by real-time polymerase chain reaction.

140 scopy and quantitative reverse transcription polymerase chain reactions were used to establish the in

141 trols, n = 23) were analyzed by quantitative polymerase chain rection to measure expression of IL28A,

142 competition leads to perturbation of the IAV polymerase complex, thereby limiting polymerase activity

143 y pivotal roles in assembling the functional polymerase complex, which is essential for the replicati

144 resent the structure of Escherichia coli RNA polymerase complexed with NusG.

145 The polymerase component, which contains a conserved C-termi

146 nd replicated by the viral RNA-dependent RNA polymerase, composed of the subunits PA, PB1, and PB2.

147 ously generated by slippage of the viral RNA polymerase confer a translational advantage.

148 The polymerase conformation is affected by the methyltransfe

149 that the polymerase assembles into a central polymerase core and several auxiliary highly flexible, p

150 of the nonessential omega-subunit of the RNA polymerase core in the DeltarpoZ strain of the model cya

151 is the opposite between cancers with mutated polymerases delta and epsilon, consistent with the role

152 depends on the proofreading activity of DNA polymerase-delta, although the repair proteins Msh2, Mlh

153 Based on its crystal structure, the RNA polymerase domain contains two Mg(II) ions.

154 te the mechanism by which the model Y-family polymerase, Dpo4, bypasses a (+)-cis-B[a]P-N (2)-dG addu

155 ecognition proteins with the replicative DNA polymerases during DNA replication has suggested that DN

156 id-phase fixation of the engineered capsular polymerases enabled rapid production of capsular polysac

157 uring DNA replication has suggested that DNA polymerase epsilon (Pol epsilon) may also play a role in

158 The replicative DNA polymerase epsilon (Pol epsilon) was shown to activate t

159 way to identify and bioinformatically remove polymerase errors that otherwise make detection of these

160 ed iNOS, nitrotyrosine, and poly-ADP-ribosyl polymerase expression and inhibited CAR-induced apoptosi

161 e configuration among different nucleic acid polymerase families, (b) the origin and phylogenetic dis

162 appropriate translesion DNA synthesis (TLS) polymerase, followed by PCR amplification and next-gener

163 eins may explain differences between them in polymerase function and immune evasion.

164 y mutagenic in genetic backgrounds where DNA polymerase function or MMR activity is partially comprom

165 tablish that leading- and lagging-strand DNA polymerases function independently within a single repli

166 ), adenylate/guanylate kinase, and human DNA polymerase gamma.

167 t mutations were identified in the viral RNA polymerase gene A24R, which seem to act through differen

168 measure the location of actively engaged RNA polymerase genome wide.

169 The polymerase GT modules are separated from the GT99 chain

170 mechanism of nucleotide incorporation by DNA polymerases has been extensively studied structurally an

171 Thus, multi-subunit replicative DNA polymerase holoenzymes are present in all three domains

172 telomerase, and the mitochondrial human DNA polymerase (hpol) gamma have been shown to tolerate an e

173 R-loops accumulate in nucleoli during RNA polymerase I (RNAP I) transcription.

174 onally, Cu(II) chelated PyED outcompetes DNA polymerase I to successfully inhibit template strand ext

175 that nucleolar SmgGDS interacts with the RNA polymerase I transcription factor upstream binding facto

176 he degradation of Rpb1, a subunit of the RNA polymerase II (Pol II) complex, and therefore hampers gl

177 l domain (CTD) of the largest subunit of RNA polymerase II (Pol II) orchestrates dynamic recruitment

178 RNA polymerase II (Pol II) pauses downstream of the transcri

179 Active NL genes with higher RNA polymerase II (Pol II) recruitment levels tend to displa

180 step in gene expression, which requires RNA polymerase II (pol II) to escape promoter proximal pausi

181 In eukaryotes, RNA polymerase II (pol II) transcribes all protein-coding ge

182 The RNA polymerase II (Pol II) transcription elongation factor,

183 plate strand that block translocation of RNA polymerase II (Pol II).

184 RNA polymerase II (Pol2) movement through chromatin and the

185 ation and regulation of transcription by RNA polymerase II (RNAPII) in eukaryotes rely on the transcr

186 script elongation of subsets of genes by RNA polymerase II (RNAPII) in the chromatin context.

187 Given that the elongating RNA polymerase II (RNAPII) stalls at this well positioned nu

188 PRC-bound genes actively transcribed by RNA polymerase II (RNAPII).

189 TFIID binds promoter DNA to recruit RNA polymerase II and other basal factors for transcription.

190 ied transcriptome-wide binding sites for RNA polymerase II and the exosome cofactors Mtr4 (TRAMP comp

191 In absence of HBV replication, RNA polymerase II associated with SALL4 exon1.

192 Processive elongation of RNA Polymerase II from a proximal promoter paused state is a

193 yo-electron microscopy map of a Mediator-RNA polymerase II holoenzyme reveals that changes in the str

194 nable decrease in the elongating form of RNA polymerase II in either mutant.

195 gnals from transcriptional regulators to RNA polymerase II in eukaryotes.

196 n occupancy of serine 2-unphosphorylated RNA polymerase II is increased, and that of topoisomerase 1,

197 sis of public datasets detected increases in polymerase II occupancy in DoG regions after heat shock,

198 rium ND2006 (Lb) in plants, using a dual RNA polymerase II promoter expression system.

199 such as transcription factor occupancy, RNA polymerase II recruitment and initiation, nascent transc

200 Fusing Set1 to RNA polymerase II results in H3K4me2 throughout transcribed

201 reased binding of total and phospho-Ser2 RNA polymerase II specifically at the intron retained under

202 Upon inhibiting RNA polymerase II termination via depletion of the cleavage/

203 creased recruitment of NF-kappaB p65 and RNA polymerase II to COX-2 and IL-8 promoters.

204 t both enhancer classes are enriched for RNA Polymerase II, CBP, and architectural proteins but there

205 ction of VIP proteins, components of the RNA polymerase II-associated factor 1 complex (Paf1c).

206 ulatory element for genes transcribed by RNA polymerase II.

207 which regulates transcription pausing of RNA-polymerase II.

208 e expression of all genes transcribed by RNA polymerase II.

209 RNA polymerase III (RNAPIII) components, including Rpc53, Rp

210 tions as gRNAs expressed from individual RNA polymerase III promoters.

211 selected the BRF1 gene, which encodes an RNA polymerase III transcription initiation factor subunit f

212 g, SINE-seq), which selectively profiles RNA Polymerase III-derived SINE RNA, thereby identifying tra

213 (C1008-->A) or silencing of poly ADP-ribose polymerase in ECs of mice prevented PMN transmigration.

214 triggers reverse conformational changes in a polymerase in order to complete a full catalytic cycle a

215 e transcribed by the viral RNA-dependent RNA polymerase in the cell nucleus before being exported to

216 verage rate and substrate specificity of XNA polymerases in a standard qPCR instrument.

217 v1 is unique among translesion synthesis DNA polymerases in employing a protein-template-directed mec

218 d epsilon, consistent with the role of these polymerases in replication of the lagging and the leadin

219 synthesis by the leading- and lagging-strand polymerases in the replisome must be coordinated to avoi

220 r of long-term response to poly (ADP-ribose) polymerase inhibition and that restoration of homologous

221 is an inhibitor of nuclear poly (ADP-ribose) polymerases (inhibition of PARP-1 > PARP-2 > PARP-3), fo

222 long-term responses to the poly (ADP-ribose) polymerase inhibitor olaparib are observed in patients w

223 In the case of favipiravir, a polymerase inhibitor with activity against ZIKV, we pred

224 Rucaparib, a poly(ADP-ribose) polymerase inhibitor, has anticancer activity in recurre

225 d previous treatment with a poly(ADP-ribose) polymerase inhibitor.

226 he paralogous TFS4 evolved into a potent RNA polymerase inhibitor.

227 sofosbuvir, ledipasvir and a non-nucleoside polymerase-inhibitor (GS-9669) or a protease-inhibitor (

228 for cellular sensitivity to poly(ADP-ribose) polymerase inhibitors (PARPi) in BRCA1-deficient cancers

229 Here we determine how human DNA polymerase-iota (Poliota) promotes error-free replicatio

230 wing that the 3'-exonuclease function of the polymerase is not needed.

231 Our approach, termed polymerase kinetic profiling (PKPro), involves monitorin

232 nin-neuraminidase (HN) and RNA-dependent RNA polymerase (L) genes of the PIV5 genome [PIV5-RSV-F (HN-

233 stingly, downregulated genes exhibit reduced polymerase levels in gene bodies, but not at promoters,

234 riptional folding of G-quadruplex inside the polymerase machinery in cells.

235 in C. roseus cells was confirmed by Poly(A) Polymerase-Mediated Rapid Amplification of cDNA Ends (PP

236 Replicative DNA polymerases misincorporate ribonucleoside triphosphates

237 10(-6)), and human mitochondrial POLRMT (RNA polymerase mitochondrial) (2 x 10(-5)) indicate high acc

238 factors, and ability to hydrogen bond to the polymerase modulates rapid and accurate information deco

239 erimentally, we could detect small viral RNA polymerase molecules, distributed randomly among binding

240 riptome-wide epimutations resulting from RNA polymerase mutants and oxidative stress.

241 of the interactions between the dengue virus polymerase NS5 and SLA in solution has not been performe

242 delity relies on the concerted action of DNA polymerase nucleotide selectivity, proofreading activity

243 ng steric hindrance on the RNA-dependent RNA polymerases of diverse positive-stranded RNA viruses.

244 with the multi-subunit B-family replicative polymerases of eukaryotes.

245 Thus, as opposed to sole regulation by actin polymerases operating at their tips, the protrusion effi

246 as the remarkable ability to act either as a polymerase or as a destabilizer of the microtubule plus

247 regulation of chromosomal proteins like DNA polymerases or kinetochore kinases, are demonstrating th

248 des a multifunction reverse transcriptase or polymerase (P), which is composed of several domains.

249 Polyadenylation of nascent RNA by poly(A) polymerase (PAP) is important for 3' end maturation of a

250 panosomes possess two canonical RNA poly (A) polymerases (PAPs) termed PAP1 and PAP2.

251 ay for the discovery of the poly(ADP-ribose) polymerase (PARP) family of enzymes and the ADP-ribosyla

252 Olaparib, a poly(ADP-ribose) polymerase (PARP) inhibitor, has previously shown effica

253 tankyrase proteins (TNKS), poly(ADP-ribose) polymerases (PARP) that regulate Wnt signaling by target

254 isms by which inhibition of poly(ADP-ribose) polymerases (PARPs) elicits clinical benefits in cancer

255 ified 12 primary miRNAs with significant RNA polymerase pausing alterations after JQ1 treatment; each

256 ports a model in which translesion synthesis polymerases perform a slippage and realignment extension

257 the exchange of the E. coli replicative DNA polymerase Pol IIIcore with the translesion polymerases

258 polymerase Pol IIIcore with the translesion polymerases Pol II and Pol IV.

259 DNA polymerase (Pol) beta maintains genome fidelity by catal

260 In the current study, we examined DNA polymerase (pol) gamma and pol beta as possible compleme

261 For transcription through chromatin, RNA polymerase (Pol) II associates with elongation factors (

262 spho-Ser 2 carboxy-terminal domain (CTD) RNA polymerase (Pol) II formation on the promoters of IRF1,

263 the NHEJ enzymatic components consisting of polymerases (Pol mu and Pol lambda), a nuclease (the Art

264 lls expressing partner proteins that promote polymerase production will produce higher copy numbers o

265 lular metabolism that reinforce thermostable polymerase production.

266 Mutations preventing DNA polymerase proofreading activity or MMR function cause m

267 We expressed RABV large polymerase protein (L) in insect cells from a recombinan

268 GRO-Seq analysis showed the polymerase reading through the termination signal in the

269 genetic distances were calculated using the polymerase region.

270 g D-stereoselectivity exhibited by human DNA polymerases relative to viral reverse transcriptases.

271 slesion DNA synthesis (TLS), specialized DNA polymerases replicate the damaged DNA, allowing stringen

272 lication depends on primase, the specialised polymerase responsible for synthesis of the RNA primers

273 structures of the translesion DNA synthesis polymerase Rev1 in complex with three of the four possib

274 t to involve direct interactions between RNA polymerase (RNAP) and the translational machinery.

275 accessible rut site promotes pausing of RNA polymerase (RNAP) at a single Rho-dependent termination

276 S531 of Escherichia coli RNA polymerase (RNAP) beta subunit is a part of RNA binding

277 obally regulate transcription by binding RNA polymerase (RNAP) holoenzyme and competing with promoter

278 The Escherichia coli RNA polymerase (RNAP) is a multisubunit protein complex cont

279 Mtb RNA polymerase (RNAP) is the target of the first-line antitu

280 nfection by coliphage lambda by stalling RNA polymerase (RNAP) translocation specifically on lambda D

281 demonstrate that MglA-SspA, which binds RNA polymerase (RNAP), also interacts with the C-terminal do

282 Single-subunit RNA polymerases (RNAPs) are present in phage T7 and in mitoc

283 Gene transcription is carried out by RNA polymerases (RNAPs).

284 GII.P16 polymerase sequences associated with GII.2 and GII.4 Syd

285 Accordingly, a mutation in RNA polymerase that diminished the impact of AT-rich DNA on

286 Engineered polymerases that can copy genetic information between DN

287 ates a potent inhibitor of several human DNA polymerases that can replicate damaged DNA.

288 Tankyrase 1 and 2 are poly(ADP-ribose) polymerases that function in pathways critical to cancer

289 es transcription mediated by all nuclear RNA polymerases, thereby acting as a positive modifier of gl

290 by approximately 80%, permits recoupling of polymerase to helicase.

291 ing stringent DNA synthesis by a replicative polymerase to resume beyond the offending damage.

292 We show that KPAF3 recruits KPAP1 poly(A) polymerase to the 3' terminus, thus leading to pre-mRNA

293 e N-terminal region of mtRNAP to recruit the polymerase to the promoter whereas TFB2M induces structu

294 e-molecule assays with fluorescently labeled polymerases to demonstrate that the Pol III* complex (ho

295 timulates PPi dissociation and occurs before polymerase translocation.

296 detected were associated with more than one polymerase type, including GI.3, GII.2, GII.3, GII.4 Syd

297 rmore, the density of antisense transcribing polymerase upstream of the promoter region exhibited an

298 r portion of the RdDM pathway, including RNA POLYMERASE V (POL V), DOMAINS REARRANGED METHYLTRANSFERA

299 ty to amplify both DNA and RNA targets using polymerase with both reverse-transcriptase and strand di

300 Accordingly, DNA polymerase zeta activity was essential for mutagenesis i