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1 pe or source, we found in vivo fibrils to be polymorphic.
2 DPYD*2A, of whom 22 (1.1%) were heterozygous polymorphic.
3 e unlinked, structurally complex, and highly polymorphic.
4 These fibrils are highly polymorphic.
5 ned between the two parental lines, 329 were polymorphic.
6 eta fibrils comprising hydrogels may also be polymorphic.
7 GGAA-microsatellites are highly variable and polymorphic.
12 e MOF in two different solvents leads to two polymorphic activated forms with very different pore ope
13 polymorphism (SNP), which is also found in a polymorphic allele of OsSWEET13 known as the recessive r
15 fficient rate of DNA strand exchange between polymorphic alleles, Dmc1 must also guard against recomb
16 ons over short time periods-too short to fix polymorphic alleles-is described as incomplete lineage s
19 resents a >20-fold increase in the number of polymorphic Alu elements associated with human phenotype
21 ought to determine if there are instances of polymorphic Alu insertion variants that function in a co
24 stricted subset of L1HS-Ta loci - some being polymorphic among individuals - significantly contribute
25 ats (STRs), which constitute one of the most polymorphic and abundant repeat classes, to gene express
26 78) of CRC samples; DATE truncation was also polymorphic and detected in 18% (13 of 78) of CRC tissue
27 h individual cohort helps gain insights into polymorphic and disease-associated variants, a joint per
28 the air, offering a useful route to generate polymorphic and hierarchical regenerated silk fibers wit
31 ifferent classes of Ag that are presented by polymorphic and monomorphic Ag-presenting molecules of t
33 t that Arp2/3 complex conformation is highly polymorphic and that its activities can be controlled co
34 rast to other IgG subclasses, IgG3 is highly polymorphic and usually contains an arginine at position
38 owever, this vulnerable site is structurally polymorphic, and designing immunogens that present diffe
39 osomal copies of the human genome are highly polymorphic, and the allelic content on each strand can
41 we use the diet specialization often seen in polymorphic Arctic charr (Salvelinus alpinus) population
44 However, this epitope region is structurally polymorphic as it can also form a helical conformation r
46 tablished that amyloid fibrils are generally polymorphic at the molecular level, with a given peptide
48 and AFM imaging of C. albicans confirmed the polymorphic behavior of both strains, which was dependen
52 flexibility in genotyping applications, SNPs polymorphic between tetraploid and diploid species were
53 Using the IUCN red list, we then showed that polymorphic bird species are at lesser risk of extinctio
55 MHC-II is variable not only in amino acids (polymorphic) but also in its biology, with consequences
56 Assemblies of these oligonucleotides are polymorphic, but may be controlled by solution pH and co
58 etroviral capsid protein (CA) assembles into polymorphic capsids, whose architecture, assembly, and s
61 uck, the polar flagellar filament executes a polymorphic change into a spiral-like form that wraps ar
62 ferences in transcription factors binding to polymorphic cis-regulations and to differences in trans-
63 in 54 564 markers that produced high-quality polymorphic clusters between diploid species, 47 116 pol
66 ) of circular muscle IMAs issued specialized polymorphic collaterals to myenteric ganglia, and a subs
68 ofilaments laterally associate in vitro into polymorphic condensates typically imaged on surfaces.
69 nized wheat starch displayed notably similar polymorphic conversion, from the beta' to beta form over
70 We find frequent recurrence of mutations at polymorphic CpG sites, and an increase in C to T mutatio
74 ltiplex PCR assay, based on random amplified polymorphic DNA (RAPD) analysis was developed for its ef
76 profiles followed by Random Amplification of Polymorphic DNA (RAPD)-PCR fingerprinting was used to gr
78 analysis made using random amplification of polymorphic DNA and directed amplification of mini satel
81 tive consensus sequence, and the presence of polymorphic elements within common marmoset populations,
83 ferent evolutionary ages (young in vitro and polymorphic ERVs, older fixed ERVs) allowed us to disent
84 ro HERV-Ks in human, and 1,624 fixed and 242 polymorphic ETns, as well as 3,964 fixed and 1,986 polym
86 a) peptide of Alzheimer's disease (AD) forms polymorphic fibrils on the micrometer and molecular scal
87 rming peptides and proteins to assemble into polymorphic fibrils suggests that cross-beta fibrils com
91 lower onset melting temperatures, and major polymorphic form transformed from alpha to beta and/or b
92 temperatures and enthalpy of melting of the polymorphic form V, at higher storage temperatures, achi
94 ) microscopy for rapid discrimination of two polymorphic forms of the small molecule d-mannitol is pr
97 esses are of key importance to the growth of polymorphic functional compounds such as TiO2, where mat
99 idence suggest that members from ancient and polymorphic gene families such as defensins and receptor
101 form of malaria, has highlighted two related polymorphic genes called dblmsp and dblmsp2, which encod
102 diversity help to elucidate the evolution of polymorphic genes involved in Red Queen co-evolution.
104 und within the MHC are among the most highly polymorphic genes of vertebrate genomes, providing popul
105 steroid metabolism among morphs and identify polymorphic genes within the inversion that are likely t
109 ompatibility complex (MHC) contains the most polymorphic genetic system in humans, the human leukocyt
110 gh we identified MHC presentation of private polymorphic germline alleles, no mutated peptides were r
111 eport analysis of a total of 36 nonreference polymorphic HERV-K proviruses, including 19 newly report
113 art by sequence-specific binding of PRDM9, a polymorphic histone H3 (H3K4Me3) methyltransferase.
114 ately determines the sequences of the highly polymorphic HLA class I and HLA class II genes and the c
123 distinct chronically infected cell line are polymorphic in nature, with many particles lacking organ
124 Functional short tandem repeats (STR) are polymorphic in the population, and the number of repeats
125 lbicollis from its sister species and may be polymorphic in Z. albicollis due to a past hybridization
127 .9 and 0.183 to 0.926, respectively, and the polymorphic information content value over all populatio
128 alysis, genetic diversity, allele frequency, polymorphic information content, and population structur
129 sequence identity and the existence of many polymorphic insertions absent from the reference genome,
130 ought to determine the extent to which other polymorphic insertions are present in humans, using sequ
132 ylation site in the envelope (E) protein, is polymorphic; it is absent in many of the African isolate
135 pe glycoprotein and identified two naturally polymorphic key residues that afford immunosuppressive a
136 Here we comprehensively mapped fixed and polymorphic L1HS-Ta copies in 12 commonly-used somatic c
137 eptide-related sequence A (MICA) is a highly polymorphic ligand of the activating NKG2D receptor on n
138 subset of which is present as insertionally polymorphic loci that include approximately full-length
140 everal gene families characterized by highly polymorphic loci with extensive nucleotide diversity, co
141 esult from the analysis is that alleles at a polymorphic locus play the role of genetic cues, in the
142 ry factor (MIF) is encoded in a functionally polymorphic locus that is linked to the susceptibility o
143 s (TCRs) interact with peptides bound to the polymorphic major histocompatibility complex class Ia (M
144 hic clusters between diploid species, 47 116 polymorphic markers between cultivated and interspecific
146 hort tandem repeat (STR) variants are highly polymorphic markers that facilitate powerful population
154 a limited number of peptides complement the polymorphic MHC specificity determining pockets in a way
156 es glareolus, Avpr1a and Oxtr each contain a polymorphic microsatellite locus located in their 5' reg
158 viduals from 15 European populations for two polymorphic mitochondrial loci, atp6 and rps12, identifi
159 te allorecognition based on detection of the polymorphic molecule signal regulatory protein alpha (SI
162 pproach to analyze the phenotypic effects of polymorphic mutations in a mouse model of Huntington's d
163 However, small effect sizes and the often polymorphic nature of immunogenic parasite proteins make
164 ay help the proteins cope with the extremely polymorphic nature of major histocompatibility complex p
169 small populations, genetic linkage between a polymorphic neutral locus and loci subject to selection,
171 , phenotypic analysis of naturally occurring polymorphic NucS in a M. smegmatis surrogate model, sugg
175 ectional selection on blood feeding within a polymorphic population to isolate genetic differences be
176 CRs are enriched in the capacity to engage a polymorphic, positively charged "hot-spot" region that i
179 characterized by their ability to deliver a polymorphic protein toxin into the cytoplasm of a neighb
181 l subgroups included: early lesions (n = 1); polymorphic PTLD (n = 1); monomorphic PTLD (n = 27), Hod
182 s that cause the deposition of antibodies to polymorphic recipient antigens (ie, alloantibody) or non
183 ulated that the serotonin transporter-linked polymorphic region (5-HTTLPR), a common functional polym
184 onstrated that one antibody interacts with a polymorphic region overlapping two T cell epitopes, sugg
186 lex on human chromosome 6 is one of the most polymorphic regions in the human genome and contributes
187 of L6 to the weaker allele L7 identified two polymorphic regions in the TIR and the nucleotide bindin
188 earch two or more genome sequences to locate polymorphic regions suitable for designing candidate IGG
190 Here, the authors show that a non-coding polymorphic regulatory element at 7p14.3 may predispose
191 tate transcriptomes to identify a non-coding polymorphic regulatory element at 7p14.3 that associates
192 (a) and Prnp(b) polymorphism that contains a polymorphic residue at the beginning of the threonine st
193 Our study therefore reveals that HLA-DM polymorphic residues have a considerable impact on HLA-D
196 ster, we identified and de novo assembled 15 polymorphic retrocopies and found that all retroposed lo
197 mediated by eosinophils and clarify how its polymorphic self-association pathways regulate toxicity
199 tical for allowing recombination between the polymorphic sequences of homologous chromosomes, thus co
202 he immediately flanking nucleotides around a polymorphic site--the site's trinucleotide sequence cont
204 he frequency of allelic variants at two PER3 polymorphic sites (rs57875989 length polymorphism: PER3
207 equence variability, we found a number of E2 polymorphic sites that are responsible for loss of neutr
208 iated Citrobacter koseri genomes harbored 47 polymorphic sites that we used to define 10 subpopulatio
211 a unique resource of novel Single Nucleotide Polymorphic (SNP) markers for Daphnia pulicaria using th
212 ble (CNV) loci differ from single nucleotide polymorphic (SNP) sites in size, mutation rate, and mech
213 ' containing 300 genotypes identified 44,424 polymorphic SNPs and genetic diversity analysis provided
215 r the existence of alternative strategies in polymorphic species promotes the ability to adaptively r
217 tudy provides empirical evidence that highly polymorphic species-specific kinship markers can evolve
219 EA to derive mutation-rate estimates for 702 polymorphic STRs by tracing each locus over 222,000 meio
220 have estimated the mutation rates of highly polymorphic STRs by using capillary electrophoresis and
221 llization process are found to be metastable polymorphic structures that are different from the stabl
223 crystal structure among several options in a polymorphic system is an important goal in solid-state s
224 d typing service for C. glabratathat targets polymorphic tandem repeat-containing loci has recently b
226 study, we searched for associations between polymorphic TE (polyTE) loci and human gene expression l
228 e we show that proteins belonging to the LXG polymorphic toxin family present in Streptococcus interm
230 to scrutinize channel characteristics of the polymorphic TPC2 variants in direct comparison with WT.
231 e (PTC) and 6-n-propylthiouracil (PROP) is a polymorphic trait mediated by the TAS2R38 bitter taste r
232 ere were events in which filaments underwent polymorphic transformations but remained in bundles, lea
233 ron radiation X-ray diffraction, we reveal a polymorphic transition from face-centred-cubic (fcc) str
235 e, we report on electron-regulated nanoscale polymorphic transitions in silk proteins revealed by nea
236 The symmetry breaking that occurs across polymorphic transitions is often achieved by small atomi
239 ubsequently isolated fibroblasts from WT and polymorphic variant carriers for endolysosomal patch-cla
240 r model for the protofibril and suggest that polymorphic variant fibrils have different numbers of pr
242 Genetic studies have found that a common polymorphic variant in ANGPTL4 results in lower plasma t
245 h is typically seen in adult patients, and a polymorphic variant with larger lesions of variable size
248 nguish allelic products based upon expressed polymorphic variants in HTT, including rs149 109 767.
249 ce of inflammation in CRC, we tested whether polymorphic variants in this gene could affect the risk
250 hese common and normally non-disease causing polymorphic variants of A1AT have been retained by natur
251 tested under-expression, ATPase function or polymorphic variants of Msh2 and Msh3, but in disparate
258 cant associations were observed between PER3 polymorphic variants/their combinations and both diurnal
259 s SVA in XDP patients (n = 140) and detected polymorphic variation in the length of a hexanucleotide
262 rdiogram and the morphologically distinctive polymorphic ventricular tachycardia ('torsades de pointe
263 ng Long-QT syndrome (13%), catecholaminergic polymorphic ventricular tachycardia (4%), arrhythmogenic
264 mutations associated with catecholaminergic polymorphic ventricular tachycardia (CPVT) and atrial fi
265 cause arrhythmias such as catecholaminergic polymorphic ventricular tachycardia (CPVT) and long QT s
270 efficacy of flecainide for catecholaminergic polymorphic ventricular tachycardia (CPVT) is unclear.
271 gene (RYR2) cause dominant catecholaminergic polymorphic ventricular tachycardia (CPVT), a leading ca
276 ed the predominant role of catecholaminergic polymorphic ventricular tachycardia and long QT syndrome
277 tiologies established were catecholaminergic polymorphic ventricular tachycardia and long QT syndrome
278 monstrate that azithromycin can cause rapid, polymorphic ventricular tachycardia in the absence of QT
279 with long QT syndrome and catecholaminergic polymorphic ventricular tachycardia received routine bet
280 and long QT, Brugada, and catecholaminergic polymorphic ventricular tachycardia syndromes) should al
281 diac death cases linked to catecholaminergic polymorphic ventricular tachycardia that feature lethal
283 icular cardiomyopathy, and catecholaminergic polymorphic ventricular tachycardia were the most common
284 genetic arrhythmia syndrome characterized by polymorphic ventricular tachycardia with physical or emo
285 e, 9; Brugada syndrome, 8; catecholaminergic polymorphic ventricular tachycardia, 3; short QT syndrom
286 thmia syndromes, including catecholaminergic polymorphic ventricular tachycardia, congenital long QT
287 to study long QT syndrome, catecholaminergic polymorphic ventricular tachycardia, hypertrophic cardio
288 terozygous mice carrying a catecholaminergic polymorphic ventricular tachycardia-linked RyR2 mutation
289 NQ1, KCNH2, and SCN5A) and catecholaminergic polymorphic ventricular tachycardia-susceptibility gene
293 tachycardia, n = 44; pause/asystole, n = 36; polymorphic ventricular tachycardia/ventricular fibrilla
294 , including 669 sustained monomorphic VT, 20 polymorphic VT, 10 supraventricular tachycardia, and 3 m
297 loid-beta peptides (Abeta40 and Abeta42) are polymorphic, with variations in molecular structure that
299 ween closely related species and can even be polymorphic within species, suggesting that nascent sex
300 The genes encoding HLA proteins are the most polymorphic within the human genome, with thousands of d
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