ライフサイエンスコーパス: polymorphonuclear neutrophil

1 citation reduces tissue damage by inhibiting polymorphonuclear neutrophils.

2 ion was studied in vitro with isolated human polymorphonuclear neutrophils.

3 sis in children was associated with elevated polymorphonuclear neutrophils.

4 kin-10 (IL-10) and can inhibit chemotaxis of polymorphonuclear neutrophils.

5 ith the C5a receptor on many cells including polymorphonuclear neutrophils.

6 ther cationic peptides, serum complement, or polymorphonuclear neutrophils.

7 sonophagocytosis and killing of GAS by human polymorphonuclear neutrophils.

8 ctivation of the integrin alpha(M)beta(2) on polymorphonuclear neutrophils.

9 nership between uPAR and L-selectin in human polymorphonuclear neutrophils.

10 ithelial corneal infiltrates are composed of polymorphonuclear neutrophils.

11 ering mediates activation signaling in human polymorphonuclear neutrophils.

12 profile and impaired antifungal activity of polymorphonuclear neutrophils.

13 rs (degree of fibrosis) and concentration of polymorphonuclear neutrophils.

14 ollagenase thought to be expressed mainly by polymorphonuclear neutrophils.

15 is and reactive oxygen species generation in polymorphonuclear neutrophils.

16 hrough its actions on gammadelta-T cells and polymorphonuclear-neutrophils, 27-hydroxycholesterol fun

17 Polymorphonuclear neutrophil A3 receptors expression det

18 Myeloperoxidase, a heme enzyme released by polymorphonuclear neutrophils, accumulates within ischem

19 tic ketoacidosis is associated with systemic polymorphonuclear neutrophil activation and degranulatio

20 ted in partial inhibition of IL-8-stimulated polymorphonuclear neutrophil adhesion, and treatment wit

21 Polymorphonuclear neutrophils also express A3 adenosine

22 2-triggered neutrophilia and monocytosis and polymorphonuclear neutrophil and monocyte renal infiltra

23 cluded albumin leak into lung and buildup of polymorphonuclear neutrophils and cytokines/chemokines i

24 2B2 cells were compared with those of bovine polymorphonuclear neutrophils and lymphocytes.

25 With human polymorphonuclear neutrophils and macrophages, RvD1, RvD

26 icates the inflammatory response mediated by polymorphonuclear neutrophils and monocytes as the key e

27 which are cationic antimicrobial peptides of polymorphonuclear neutrophils and other leukocytes, are

28 hlamydia-specific immunoglobulin G (IgG) and polymorphonuclear neutrophils and show the importance of

29 00 magnification to quantitate the number of polymorphonuclear neutrophils and squamous epithelial ce

30 that this oxysterol increases the number of polymorphonuclear-neutrophils and gammadelta-T cells at

31 tions of 27-hydroxycholesterol requires both polymorphonuclear-neutrophils and gammadelta-T cells, an

32 ing the migration of monocytes, neutrophils, polymorphonuclear neutrophils, and dendritic cells into

33 Ceramide levels increase in activated polymorphonuclear neutrophils, and here we show that end

34 since leukocyte depletion by irradiation or polymorphonuclear neutrophil anti-serum pre-treatment el

35 n by reducing side effects in patients whose polymorphonuclear neutrophils are activated before hyper

36 Taken together, these findings suggest that polymorphonuclear neutrophils are capable of producing I

37 Of all the polymorphonuclear neutrophil azurophilic enzymes examine

38 , possibly due to the release of destructive polymorphonuclear neutrophil azurophilic enzymes.

39 to perforation, increased bacterial load and polymorphonuclear neutrophils, but decreased IFN-gamma a

40 d Y. pestis' ability to counter lysozyme and polymorphonuclear neutrophils, but it did not affect the

41 perinodal adipose tissues and non-apoptotic polymorphonuclear neutrophils carrying engulfed zymosan

42 Polymorphonuclear neutrophils constitute the first line

43 We now show that activated human polymorphonuclear neutrophils convert NO2- into NO2Cl an

44 eninges, parenchyma, and choroid plexus were polymorphonuclear neutrophil dependent, since leukocyte

45 is a hallmark of vascular inflammation, with polymorphonuclear neutrophil-derived (PMN-derived) and m

46 These results implicate DPPI and polymorphonuclear neutrophil-derived serine proteases in

47 protease stored in the azurophil granules of polymorphonuclear neutrophils, digests microbes after ph

48 binding; binding to FcgammaRI; activation of polymorphonuclear neutrophils; effect on the Ab-combinin

49 In this study, we show that polymorphonuclear neutrophils from mice deficient in ser

50 ased N-NO-IQ formation was not detected with polymorphonuclear neutrophils from two unrelated MPO-def

51 express A3 adenosine receptors that enhance polymorphonuclear neutrophil functions.

52 Polymorphonuclear neutrophil granulocytes (neutrophils)

53 translates into increased transmigration of polymorphonuclear neutrophil granulocytes across endothe

54 demonstrated an attenuated extravasation of polymorphonuclear neutrophil granulocytes in Sema7a-defi

55 l/6 mice; P<.05) and decreased percentage of polymorphonuclear neutrophils in bronchoalveolar lavage

56 timulated EC also bound increased numbers of polymorphonuclear neutrophils in cellular adhesion assay

57 increasing macrophage ingestion of apoptotic polymorphonuclear neutrophils in vivo and in vitro, and

58 y binds to circulating and sequestered human polymorphonuclear neutrophils in vivo, eliminating in vi

59 and possibly inflammatory monocytes, but not polymorphonuclear neutrophils, in clearing HSV-1 from th

60 Sequestration of polymorphonuclear neutrophils (increased myeloperoxidase

61 saline resuscitation inhibits or aggravates polymorphonuclear neutrophil-induced acute lung injury.

62 7 and induced superoxide anion production by polymorphonuclear neutrophils; induction of the oxidativ

63 ilencing also increased bacterial counts and polymorphonuclear neutrophil infiltration in BALB/c corn

64 n of TNF-alpha and IL-1beta and interstitial polymorphonuclear neutrophil infiltration in vitro and i

65 ion, resulting in a prolonged stimulation of polymorphonuclear neutrophil influx into cornea.

66 racterized by microvascular permeability and polymorphonuclear neutrophil influx.

67 ation, there was a predominant infiltrate of polymorphonuclear neutrophils into the bladder.

68 Infiltration of polymorphonuclear neutrophils into the lung is an import

69 rain barrier permeability and recruitment of polymorphonuclear neutrophils into the tissue around the

70 (INT) reductase activity of disrupted bovine polymorphonuclear neutrophils is closely associated with

71 INT diaphorase activity of disrupted bovine polymorphonuclear neutrophils is shown to be resolved by

72 We further found that polymorphonuclear neutrophils isolated from normal donor

73 mRNA from human polymorphonuclear neutrophil leucocytes (PMNs) was probe

74 of Blood, Sapey et al. report that the human polymorphonuclear neutrophil leukocyte (or neutrophil) u

75 In polymorphonuclear neutrophils, leukocyte-specific protei

76 er, initiating steps leading to tethering of polymorphonuclear neutrophil leukocytes to the vascular

77 igration process of host inflammatory cells (polymorphonuclear neutrophils, macrophages) into the inf

78 We have shown that polymorphonuclear neutrophils mediate the covalent cross

79 Polymorphonuclear neutrophil-mediated inactivation of en

80 Polymorphonuclear neutrophil-mediated nitration and chlo

81 phenolic substrates, confirming its role in polymorphonuclear neutrophil-mediated nitration reaction

82 Polymorphonuclear neutrophils, monocytes, and macrophage

83 Endothelial cell injury by polymorphonuclear neutrophil (neutrophil [PMN]) respirat

84 ce was accompanied by a reduction in corneal polymorphonuclear neutrophil number, bacterial load, and

85 ed as the 47-kD protein overexpressed in the polymorphonuclear neutrophils of patients with a rare ne

86 intracellular IFN-gamma was identified as a polymorphonuclear neutrophil on the basis of its reactiv

87 h reactive oxygen species production by oral polymorphonuclear neutrophils (oPMNs) in chronic periodo

88 GFR, fibroblast growth factor receptor; PMN, polymorphonuclear neutrophil; PDGF, platelet-derived gro

89 ed as visible urethral discharge and/or >/=5 polymorphonuclear neutrophils per high-powered field; n

90 hermore, these studies strongly suggest that polymorphonuclear neutrophils play an important role in

91 y agents yet their mechanism(s) for blocking polymorphonuclear neutrophil (PMN) accumulation at sites

92 perated calcium entry (SOCE) is required for polymorphonuclear neutrophil (PMN) activation in respons

93 Polymorphonuclear neutrophil (PMN) activation is pivotal

94 adenosine triphosphate (ATP) contributes to polymorphonuclear neutrophil (PMN) activation leading to

95 iphosphate (ATP) and adenosine in regulating polymorphonuclear neutrophil (PMN) activation, fibrin fo

96 lly relevant concentrations of ONOO- inhibit polymorphonuclear neutrophil (PMN) adhesion to the endot

97 rochetes, TNF-like and IL-1-like activities, polymorphonuclear neutrophil (PMN) chemotaxis-inducing a

98 re strongly related to BAL total protein and polymorphonuclear neutrophil (PMN) concentration, wherea

99 ied by a delay in the rise of the peripheral polymorphonuclear neutrophil (PMN) count and a paucity o

100 -onset periodontal disease associated with a polymorphonuclear neutrophil (PMN) defective migratory r

101 Several types of polymorphonuclear neutrophil (PMN) deficiency are a pred

102 Myeloperoxidase (MPO) is released during polymorphonuclear neutrophil (PMN) degranulation, and me

103 coconjugated ligands are essential for blood polymorphonuclear neutrophil (PMN) extravasation into in

104 Polymorphonuclear neutrophil (PMN) extravasation require

105 formed to determine aging-related changes in polymorphonuclear neutrophil (PMN) function after cornea

106 ine receptors CXCR1 and CXCR2 are central to polymorphonuclear neutrophil (PMN) function.

107 To determine whether platelet and polymorphonuclear neutrophil (PMN) functions require spe

108 to facilitate immune complex (IC)-stimulated polymorphonuclear neutrophil (PMN) functions.

109 metabolite, adenosine, are key regulators of polymorphonuclear neutrophil (PMN) functions.

110 nt, a myeloperoxidase (MPO) assay to measure polymorphonuclear neutrophil (PMN) infiltrate, real-time

111 cin treatment also increased clinical score, polymorphonuclear neutrophil (PMN) infiltration (determi

112 Early preclinical events include polymorphonuclear neutrophil (PMN) infiltration and neov

113 heral organs in the two groups, WNV-infected polymorphonuclear neutrophil (PMN) infiltration and vira

114 onfirmed with synthetic MaR1, i.e., limiting polymorphonuclear neutrophil (PMN) infiltration in murin

115 reduced level of mast cell degranulation and polymorphonuclear neutrophil (PMN) infiltration in the s

116 del of this prevalent human disease, a heavy polymorphonuclear neutrophil (PMN) infiltration of the i

117 mBD2 and mBD3 that modulate bacterial load, polymorphonuclear neutrophil (PMN) infiltration, and pro

118 r to clinical observations, a robust vaginal polymorphonuclear neutrophil (PMN) migration occurs in a

119 observations revealed that a robust vaginal polymorphonuclear neutrophil (PMN) migration occurs in s

120 in response to C. albicans, which stimulate polymorphonuclear neutrophil (PMN) migration to the vagi

121 Treatment with rVIP decreased NO levels and polymorphonuclear neutrophil (PMN) number.

122 In addition to stimulating polymorphonuclear neutrophil (PMN) production, G-CSF may

123 lamp, histopathology, bacterial counts, and polymorphonuclear neutrophil (PMN) quantitation were per

124 eta-cyclodextrin to deplete cholesterol from polymorphonuclear neutrophil (PMN) rafts and thus study

125 of the junctional epithelium (P < 0.01) and polymorphonuclear neutrophil (PMN) recruitment (P < 0.00

126 arly coordinate appearance of LT and PG with polymorphonuclear neutrophil (PMN) recruitment.

127 Human polymorphonuclear neutrophil (PMN) responses to G protei

128 ours by high lethality, vascular congestion, polymorphonuclear neutrophil (PMN) sequestration in the

129 -surface protein, plays an important role in polymorphonuclear neutrophil (PMN) transmigration across

130 CAP37 is a polymorphonuclear neutrophil (PMN)-derived inflammatory

131 and G-CSF, alone or in combination, requires polymorphonuclear neutrophil (PMN)-derived proteases.

132 ), an oligomeric enzyme, plays a key role in polymorphonuclear neutrophil (PMN)-mediated host defense

133 ne-enhancing properties that influence human polymorphonuclear neutrophil (PMN)-mediated mold hyphal

134 Pulmonary tuberculosis (TB) can present with polymorphonuclear neutrophil (PMN)-predominant alveoliti

135 1 is released in large amounts from adherent polymorphonuclear neutrophils (PMN) and binds to their c

136 activate integrin-mediated adhesion in human polymorphonuclear neutrophils (PMN) and monocytes cause

137 Polymorphonuclear neutrophils (PMN) are an important com

138 ogether with the previous demonstration that polymorphonuclear neutrophils (PMN) are critical for the

139 Polymorphonuclear neutrophils (PMN) are critical innate

140 Here we show that plastin-deficient polymorphonuclear neutrophils (PMN) are deficient in kil

141 /80(-)I-A(-) intraglomerular macrophages and polymorphonuclear neutrophils (PMN) are important in ind

142 Polymorphonuclear neutrophils (PMN) are linked invariabl

143 Polymorphonuclear neutrophils (PMN) are phagocytic cells

144 Polymorphonuclear neutrophils (PMN) are potent inflammat

145 Circulating polymorphonuclear neutrophils (PMN) are quiescent, nonad

146 Human polymorphonuclear neutrophils (PMN) chemotax to a foreig

147 Polymorphonuclear neutrophils (PMN) contain multiple dis

148 ated whether survival of the pathogen inside polymorphonuclear neutrophils (PMN) contributes to the p

149 We find that human polymorphonuclear neutrophils (PMN) equilibrated with a

150 Fc domain of IgG (Fc gamma R), only primate polymorphonuclear neutrophils (PMN) express an Fc gamma

151 Polymorphonuclear neutrophils (PMN) facilitate melanoma

152 s, the biologic forms and function of PR3 in polymorphonuclear neutrophils (PMN) from healthy donors

153 Polymorphonuclear neutrophils (PMN) have distinct phenot

154 The role of polymorphonuclear neutrophils (PMN) in mediating diabeti

155 Polymorphonuclear neutrophils (PMN) in Pseudomonas aerug

156 The primary function of polymorphonuclear neutrophils (PMN) in the immune respon

157 smic antibodies (ANCA) activate primed human polymorphonuclear neutrophils (PMN) in vitro, resulting

158 se-derived eicosanoids on apoptosis of human polymorphonuclear neutrophils (PMN) in vitro.

159 Adherence or recruitment of polymorphonuclear neutrophils (PMN) induces nuclear impo

160 IL-33) and disease severity, bacterial load, polymorphonuclear neutrophils (PMN) infiltrate, gene exp

161 Because polymorphonuclear neutrophils (PMN) interaction with ECs

162 l antibody was used to block infiltration of polymorphonuclear neutrophils (PMN) into the cornea.

163 Polymorphonuclear neutrophils (PMN) kill Cryptococcus ne

164 this study, we explored a novel function of polymorphonuclear neutrophils (PMN) NAD(P)H oxidase in t

165 In this study, the role of polymorphonuclear neutrophils (PMN) on the development o

166 Polymorphonuclear neutrophils (PMN) play a central role

167 of this study was to determine whether local polymorphonuclear neutrophils (PMN) recruitment and comp

168 e of alphaMbeta2 affected the recruitment of polymorphonuclear neutrophils (PMN) to bacterial and fun

169 t-mediated phagocytosis and firm adhesion of polymorphonuclear neutrophils (PMN) under physiological

170 ired in patients with congenital neutrophil (polymorphonuclear neutrophils (PMN)) defects.

171 is expressed on human leukocytes, including polymorphonuclear neutrophils (PMN), monocytes, and macr

172 t metabolizes glutamine, is present in human polymorphonuclear neutrophils (PMN).

173 s associated with diminished infiltration of polymorphonuclear neutrophils (PMN).

174 ation by recognizing and ingesting apoptotic polymorphonuclear neutrophils (PMN).

175 tion of alpha(M)beta(2)-mediated adhesion in polymorphonuclear neutrophils (PMN).

176 iated with significant tumor infiltration by polymorphonuclear neutrophils (PMN).

177 ) aggregation and deformability, neutrophil (polymorphonuclear neutrophil; PMN) deformability, whole-

178 Neutrophils (polymorphonuclear neutrophils; PMN) and a redundant syst

179 Polymorphonuclear neutrophil (PMNL) activation enhances

180 influenza virus is commonly associated with polymorphonuclear neutrophil (PMNL) dysfunction and cons

181 Migration of polymorphonuclear neutrophils (PMNL) from the vascular c

182 ein to the surfaces of infected cells, human polymorphonuclear neutrophils (PMNL) loaded with azithro

183 tly expressed on pulmonary epithelium and on polymorphonuclear neutrophil (PMNs) after transepithelia

184 on correlates with a vaginal infiltration of polymorphonuclear neutrophils (PMNs) and a high vaginal

185 how that stimulation of alpha7nAChR on human polymorphonuclear neutrophils (PMNs) and blood mononucle

186 its ligand, CXCL12, mediate the retention of polymorphonuclear neutrophils (PMNs) and hematopoietic s

187 e time, the expression of CD18 and ICAM-1 on polymorphonuclear neutrophils (PMNs) and hepatic cells w

188 vitro model of transepithelial migration of polymorphonuclear neutrophils (PMNs) and in human intest

189 TUNEL staining, real-time RT-PCR, polymorphonuclear neutrophils (PMNs) and macrophage (Mph

190 mice with ALI had greater increases in lung polymorphonuclear neutrophils (PMNs) and macrophage coun

191 Polymorphonuclear neutrophils (PMNs) and macrophages are

192 Polymorphonuclear neutrophils (PMNs) and NK cells are bo

193 Polymorphonuclear neutrophils (PMNs) are critical for th

194 Polymorphonuclear neutrophils (PMNs) are essential effec

195 Polymorphonuclear neutrophils (PMNs) are innate effector

196 Polymorphonuclear neutrophils (PMNs) are innate immune s

197 Polymorphonuclear neutrophils (PMNs) are largely conside

198 During pneumonia, polymorphonuclear neutrophils (PMNs) are recruited by ch

199 this infection METHODS: To determine whether polymorphonuclear neutrophils (PMNs) are required for di

200 Polymorphonuclear neutrophils (PMNs) become stuck on the

201 Notably, polymorphonuclear neutrophils (PMNs) can capture circula

202 Human polymorphonuclear neutrophils (PMNs) counteracted the pr

203 its functional relevance for recruitment of polymorphonuclear neutrophils (PMNs) during acute inflam

204 Trafficking of polymorphonuclear neutrophils (PMNs) during inflammation

205 ell infiltration with an increased number of polymorphonuclear neutrophils (PMNs) during the early st

206 Polymorphonuclear neutrophils (PMNs) express a number of

207 Polymorphonuclear neutrophils (PMNs) form the first line

208 nfection in skin involves the recruitment of polymorphonuclear neutrophils (PMNs) from the bone marro

209 Polymorphonuclear neutrophils (PMNs) have previously bee

210 fection, Tlr5(-/-) mice had lower numbers of polymorphonuclear neutrophils (PMNs) in their broncho-al

211 fect of anti-LcrV antibody extended to mouse polymorphonuclear neutrophils (PMNs) in vitro, and PMNs

212 Numerous studies have shown that polymorphonuclear neutrophils (PMNs) infiltrate the myoc

213 Polymorphonuclear neutrophils (PMNs) infiltrate tissue i

214 onse to chemoattractant stimulation in human polymorphonuclear neutrophils (PMNs) is characterized by

215 uces pro-inflammatory cytokine production by polymorphonuclear neutrophils (PMNs) of diabetic individ

216 DGKalpha function is altered in polymorphonuclear neutrophils (PMNs) of patients with lo

217 During inflammation, circulating polymorphonuclear neutrophils (PMNs) receive signals to

218 unexpected activity of a CD49d(+) subset of polymorphonuclear neutrophils (PMNs) that are found in t

219 Bone marrow (BM) holds a large reserve of polymorphonuclear neutrophils (PMNs) that are rapidly mo

220 satetraenoate (5-HETE and 5-oxoETE) activate polymorphonuclear neutrophils (PMNs) through a common, r

221 These activate human polymorphonuclear neutrophils (PMNs) through formyl pept

222 re involved in recruitment and activation of polymorphonuclear neutrophils (PMNs) to infected tissues

223 Recruitment of polymorphonuclear neutrophils (PMNs) to sites of acute i

224 ammatory cytokines followed by attraction of polymorphonuclear neutrophils (PMNs) to the site of infl

225 During inflammation polymorphonuclear neutrophils (PMNs) traverse venular wa

226 Polymorphonuclear neutrophils (PMNs) treated with a subl

227 Activation of circulating polymorphonuclear neutrophils (PMNs) was assessed by an

228 CAF2-1, SSK21, and SSK23 to killing by human polymorphonuclear neutrophils (PMNs) was assessed.

229 unt, real-time RT-PCR, and ELISA assays, and polymorphonuclear neutrophils (PMNs) were quantitated us

230 Eighty-six genes in WG PBMCs and 40 in WG polymorphonuclear neutrophils (PMNs) were significantly

231 Interactions of polymorphonuclear neutrophils (PMNs) with endothelial ce

232 count for this absence, we hypothesized that polymorphonuclear neutrophils (PMNs), recruited massivel

233 ical, and gene manipulation methods in human polymorphonuclear neutrophils (PMNs), we have identified

234 edema formation induced by the activation of polymorphonuclear neutrophils (PMNs).

235 er nonself particles, specifically apoptotic polymorphonuclear neutrophils (PMNs).

236 ADAM9 is also a product of human and murine polymorphonuclear neutrophils (PMNs).

237 ogous to CD16A and a major FcgammaR on human polymorphonuclear neutrophils (PMNs).

238 ion that is characterized by infiltration of polymorphonuclear neutrophils (PMNs; refs 1-4).

239 Neutrophils (polymorphonuclear neutrophils [PMNs]) play an elaborate

240 Blood polymorphonuclear neutrophils provide immune protection

241 Polymorphonuclear neutrophils recruited to the infected

242 endothelial cells that appear essential for polymorphonuclear neutrophil recruitment in IC disease.

243 cant differences in bacterial numbers and in polymorphonuclear neutrophil recruitment in the lungs fr

244 rease in blood-brain barrier permeability or polymorphonuclear neutrophil recruitment, but did give r

245 Polymorphonuclear neutrophils release ATP in response to

246 er, histological analyses suggested that the polymorphonuclear neutrophil response at 2 days postinfe

247 In studies of human polymorphonuclear neutrophil responses to formyl peptide

248 To test individual mosaic subpopulations of polymorphonuclear neutrophil responses, we also develope

249 whereas adoptive transfer of MD-2-competent polymorphonuclear neutrophils restored it.

250 e that is converted to adenosine, inhibiting polymorphonuclear neutrophils through A2a adenosine rece

251 ggregation initiates activation signaling in polymorphonuclear neutrophils through at least two disti

252 te inflammation by blocking the migration of polymorphonuclear neutrophils to initiate resolution.

253 Hypertonic saline triggers polymorphonuclear neutrophils to release adenosine triph

254 the adhesion of a type of white blood cell--polymorphonuclear neutrophils--to the lining of the circ

255 Interestingly, C5a-stimulated endothelial polymorphonuclear neutrophil transmigration, but not che

256 cally upregulated by the action of activated polymorphonuclear neutrophils via an unprecedented mecha

257 Elevated counts of polymorphonuclear neutrophils were detectable at 15 minu

258 eripheral blood mononuclear cells (PBMC) and polymorphonuclear neutrophils were induced to express DD

259 Polymorphonuclear neutrophils were stimulated with buffe

260 Treatment of human polymorphonuclear neutrophils with hypertonic saline bef

261 reased cellular ceramide content by treating polymorphonuclear neutrophils with sphingomyelinase C an