ライフサイエンスコーパス: polynucleotide kinase

1 RCC4, known to be bound by the FHA domain of polynucleotide kinase.

2 end repair with Klenow, T4 polymerase or T4 polynucleotide kinase.

3 Mammalian polynucleotide kinase 3' phosphatase (PNK) plays a key r

4 2 (NEIL2) and the DNA end-processing enzyme polynucleotide kinase 3'-phosphatase (PNKP) in purified

5 identification of the same homozygous PNKP (polynucleotide kinase 3'-phosphatase) mutation, c.1123G>

6 3 and identified multiple mutations in PNKP (polynucleotide kinase 3'-phosphatase) that result in sev

7 recruit end-processing enzymes, such as PNK (polynucleotide kinase 3'-phosphatase), Aprataxin and APL

8 ant for SSBR, including DNA ligase 3 (DNL3), polynucleotide kinase 3'-phosphatase, and polymerase bet

9 ccharomyces cerevisiae, a homologue of human polynucleotide kinase/3'-phosphatase, has been shown to

10 It is homologous to one domain of mammalian polynucleotide kinase/3'-phosphatase.

11 11 and His515 in the kinase module abolished polynucleotide kinase activity in vitro.

12 n used this motif to engineer ribozymes with polynucleotide kinase activity.

13 Polynucleotide kinase and aprataxin-like forkhead-associ

14 le-stranded cDNA (ss-cDNA) ligation using T4 polynucleotide kinase and CircLigase, and polymerization

15 They were substrates for T4 polynucleotide kinase and primers for Escherichia coli p

16 g 3'-blocked ends of BER intermediates, e.g. polynucleotide kinase and tyrosyl-DNA phosphodiesterase

17 ligase 1, a central domain that resembles T4 polynucleotide kinase, and a C-terminal CPD domain that

18 agment is phosphorylated by an NTP-dependent polynucleotide kinase; and (iii) the 3'-OH, 2'-PO4, and

19 ragment is phosphorylated by a GTP-dependent polynucleotide kinase; and the 3'-OH, 2'-PO(4), and 5'-P

20 Clostridium thermocellum polynucleotide kinase (CthPnk), the 5' end-healing modul

21 Clostridium thermocellum polynucleotide kinase (CthPnk), the 5'-end-healing modul

22 erminal cyclic phosphodiesterase and central polynucleotide kinase domains that heal the broken ends

23 bonuclease requires its binding partner, the polynucleotide kinase Grc3, for specific C2 cleavage.

24 g a phosphorylated primer, prepared using T4 polynucleotide kinase, into the PCR phase and subsequent

25 Polynucleotide kinase is a bifunctional enzyme containin

26 a homologue of the 3' phosphatase domain of polynucleotide kinase, is a third member of this group o

27 Nearly 50 individual DNAs with polynucleotide kinase-like activity were isolated from a

28 ant, A482T, that was defective in binding to polynucleotide kinase phosphatase (PNKP) not only retain

29 Clostridium thermocellum polynucleotide kinase-phosphatase (CthPnkp) catalyzes 5'

30 T4 polynucleotide kinase-phosphatase (Pnkp) exemplifies a f

31 Polynucleotide kinase-phosphatase (PNKP) is a DNA repair

32 for cell killing in vivo, and the bacterial polynucleotide kinase-phosphatase (Pnkp)/hua enhancer 1

33 Here, we demonstrate that a polynucleotide kinase-phosphatase enzyme from Clostridiu

34 ponent RNA repair cassette, comprising Pnkp (polynucleotide kinase-phosphatase-ligase) and Hen1 (RNA

35 osphatase domain of Clostridium thermocellum polynucleotide kinase/phosphatase (CthPnkp) belongs to t

36 egB-cleaved mRNAs depends on a functional T4 polynucleotide kinase/phosphatase (PNK).

37 T4 polynucleotide kinase/phosphatase (Pnkp) exemplifies a f

38 a hereditary disease caused by mutations in polynucleotide kinase/phosphatase (PNKP), a DNA strand b

39 important interactions of XRCC1 is that with polynucleotide kinase/phosphatase (PNKP), a dual-functio

40 NHEJ relies on polynucleotide kinase/phosphatase (PNKP), which generate

41 tic lethal partner of the DNA repair protein polynucleotide kinase/phosphatase (PNKP).

42 he bacteriophage T4 enzymes RNA ligase 1 and polynucleotide kinase/phosphatase can fulfill the tRNA a

43 Aprataxin polynucleotide kinase/phosphatase-like factor (APLF) fac

44 with accessory factors such as aprataxin and polynucleotide kinase/phosphatase-like factor (APLF).

45 ling activities and requires the action of a polynucleotide kinase (PNK) and a cyclic phosphodiestera

46 was efficiently religated in the presence of polynucleotide kinase (PNK) and human DNA ligase III (Li

47 T4 phage polynucleotide kinase (PNK) displays 5'-hydroxyl kinase,

48 T4 polynucleotide kinase (Pnk) is a bifunctional 5'-kinase/

49 T4 polynucleotide kinase (Pnk) is the founding member of a

50 T4 polynucleotide kinase (PNK) plays critical roles in regu

51 y catalyse NHEJ in vitro, we show that human polynucleotide kinase (PNK) promotes phosphate replaceme

52 removal of the 3' phosphate is dependent on polynucleotide kinase (PNK), and not APE.

53 e dual function mammalian DNA repair enzyme, polynucleotide kinase (PNK), facilitates strand break re

54 T4 polynucleotide kinase (Pnk), in addition to being an inv

55 thophosphate from [gamma-32P]ATP mediated by polynucleotide kinase (PNK); (iv) chromatographic or ele

56 phorylated product produced by reaction with polynucleotide kinase, potentially indicating simultaneo

57 to trnfM; the termini could be labeled with polynucleotide kinase, suggesting that they result from

58 The new assays described herein are for T4 polynucleotide kinase, the DNA repair enzymes uracil-DNA

59 The fragments could be relabeled with polynucleotide kinase to yield highly purified, high-spe

60 (here named TPP1) is shown to encode only a polynucleotide kinase-type 3'-phosphatase.

61 T4-polynucleotide kinase was used to enzymatically substitu

62 Label, incorporated using [gamma-32P]ATP and polynucleotide kinase, was increased in proportion to th