ライフサイエンスコーパス: polypeptide backbone

1 drophobic moieties and groups located on the polypeptide backbone).

2 rgetic cost associated with solvation of the polypeptide backbone.

3 EM effect is most likely due to 14N from the polypeptide backbone.

4 ns near the N terminus and C terminus of the polypeptide backbone.

5 ains for each chain, where the S-S spans the polypeptide backbone.

6 anization of glycans that decorate the mucin polypeptide backbone.

7 ns to position the charges distally from the polypeptide backbone.

8 dation process, which causes cleavage of the polypeptide backbone.

9 x and a minority state of locally disordered polypeptide backbone.

10 idues, thereby adding an extra carbon to the polypeptide backbone.

11 in the formation of a deep trefoil knot in a polypeptide backbone.

12 ancer-related antigens displayed on a single polypeptide backbone.

13 step to produce an acylimine linkage in the polypeptide backbone.

14 ric interactions between side chains and the polypeptide backbone.

15 changes involve substantial ordering of the polypeptide backbone.

16 ions and is lined by carbonyl oxygens of the polypeptide backbone.

17 the first 30 amino acids within the E1A 1-80 polypeptide backbone.

18 ts cannot be classified as good solvents for polypeptide backbones.

19 n the extent of sugar modifications of their polypeptide backbones.

20 quences without the geometric constraints of polypeptide backbones.

21 the selectivity filter residues, rather than polypeptide backbones.

22 tides must originate, at least partially, in polypeptide backbones.

23 ins and is a useful model system for generic polypeptide backbones.

24 t temperatures is a poor solvent for generic polypeptide backbones.

25 rea, packing angle, and distance between the polypeptide backbones.

26 cant alterations in the conformations of the polypeptide backbones.

27 Although the MSP1a polypeptide backbone alone was adherent to tick cell ext

28 cross cell membrane, the isotope exchange of polypeptide backbone amide hydrogens of hemoglobin was c

29 MR dynamics studies have been undertaken for polypeptide backbone amide N-H bond vectors for both the

30 inewidths of Raman bands associated with the polypeptide backbone (amide I) exhibit progressive narro

31 Our results show that the majority of the polypeptide backbone amino acid residues of deoxy- and c

32 riences diminished hydrogen bonding with the polypeptide backbone, an Asp at position 3 forms a biden

33 e divided into two sub-problems, placing the polypeptide backbone and adding side-chains.

34 The polypeptide backbone and buried side chains are well ord

35 t the magic angle spectra show that both the polypeptide backbone and His(37) side chain are more con

36 gen bonding interaction between the enzyme's polypeptide backbone and its substrate.

37 m accepts three hydrogen bonds, two from the polypeptide backbone and one from the positively-charged

38 own how the spatial relationship between the polypeptide backbone and the DNA helps to determine what

39 nges in the spatial relationship between the polypeptide backbone and the DNA.

40 perturbation of a deeply buried part of the polypeptide backbone and to protonation of a carboxylic

41 side-chain imposes severe constraints on the polypeptide backbone, and thus it seems likely that it p

42 dies showed that water is a poor solvent for polypeptide backbones, and therefore, backbones form col

43 and also increased the extent to which PRPg polypeptide backbones are modified by a GAG chain.

44 recognition of the central importance of the polypeptide backbone as a determinant of protein conform

45 hydrophobic groups--a result that holds for polypeptide backbones as well.

46 known to stabilize hydrogen bonds within the polypeptide backbone, as analyzed by circular dichroism

47 e catalyzes the UV-dependent cleavage of the polypeptide backbone at both the LSGGQ motif and the nuc

48 A concurrent turn of the polypeptide backbone at Phe-245 moves the rest of the ca

49 o form a new six-membered ring, cleaving the polypeptide backbone at the 65-66 position.

50 onding interactions from 1 aa side chain and polypeptide backbone atoms of the antibody light and hea

51 cted by the sequence of sidechains along the polypeptide backbone, but despite this the developement

52 Here, we ask if polypeptide backbones can intrinsically undergo the requ

53 ding sites for the cations are formed by the polypeptide backbone carbonyl groups tilting away from t

54 Both structures permit full tracing of the polypeptide backbone chain from residues 4-356, includin

55 2+)/calmodulin activation of the kinase, the polypeptide backbone chain of myosin light chain kinase

56 The polypeptide backbone chain was traced by examination of

57 ns via multiple mechanisms that lead to both polypeptide backbone cleavage events and side chain modi

58 The role of polypeptide backbone conformation in the formation of ma

59 RMM36m, with improved accuracy in generating polypeptide backbone conformational ensembles for intrin

60 The polypeptide backbone conformations and the side-chain or

61 and straight phi,psi angles assignments, and polypeptide backbone coordinates.

62 A high degree of polypeptide backbone desolvation, and not the formation

63 The polypeptide backbone displayed a single circular dichroi

64 The polypeptide backbone dynamics of acid-unfolded apomyoglo

65 exchange (H/DX) has been used to define the polypeptide backbone dynamics of full-length methyl CpG

66 The conformational propensities and polypeptide backbone dynamics of this state have been ch

67 itored within the amide I' absorbance of the polypeptide backbone exhibit two distinct kinetics phase

68 nitored within the amide I absorbance of the polypeptide backbone exhibit two distinct relaxation pha

69 The polypeptide backbone exhibits a 2-fold axis of quasi-sym

70 YiaK has a new polypeptide backbone fold and a novel mode of recognizin

71 This protease has a unique polypeptide backbone fold and contains a novel Ser-His-H

72 that the BEACH domain has a new and unusual polypeptide backbone fold, as the peptide segments in it

73 resolution, and show that it possesses a new polypeptide backbone fold.

74 The polypeptide backbone folds into a large right-handed cyl

75 ontent modulates the intrinsic preference of polypeptide backbones for collapsed structures.

76 near the center of the octamer site, and its polypeptide backbone forms a pair of hydrogen bonds with

77 In each subunit the polypeptide backbone forms large beta-sheets and enclose

78 The polypeptide backbone forms transient, sparse hydrogen-bo

79 by low hemolytic activity, and protects the polypeptide backbone from proteolytic degradation.

80 kage between the proximal histidines and the polypeptide backbone has been broken and to characterize

81 eveal that UPRTase recognizes uracil through polypeptide backbone hydrogen bonds to the uracil exocyc

82 pronounced expansion and contraction in the polypeptide backbone, i.e., to be photoelastic.

83 actor and the amide hydrogen of the adjacent polypeptide backbone in all three oxidation states.

84 The root mean square deviation of the polypeptide backbone in the complex is 2.07 A.

85 ar [(1)H]-(15)N NOEs show that, although the polypeptide backbone in the H helix region is more flexi

86 n water leading to an intrinsic expansion of polypeptide backbones in the absence of denaturants.

87 cies and Ramachandran dihedral angles of the polypeptide backbone indicates the nature of the beta-sh

88 The role of polypeptide backbone interactions in 4-oxalocrotonate ta

89 Unlike in Rtms5, in the native protein the polypeptide backbone is cleaved between Cys62 and Met63.

90 A virtual polypeptide backbone is created by joining consecutive C

91 eins have folded configurations in which the polypeptide backbone is knotted.

92 The folding of the polypeptide backbone is nearly identical with that of tu

93 in a dimer run in parallel, and that (b) the polypeptide backbone is relatively rigid and inflexible

94 t with an increase in the flexibility of the polypeptide backbone leading to a decreased probability

95 shaft motions along the entire length of the polypeptide backbone manifested by the anticorrelation o

96 g that similar O-glycan ligands on different polypeptide backbones may be common death trigger recept

97 This strongly indicates that there are polypeptide-backbone motions activated at room temperatu

98 ded by free rotation around the bonds of the polypeptide backbone of a few amino acid residues, but d

99 f attachment of carbohydrate moieties to the polypeptide backbone of a second mycobacterial glycoprot

100 magnetic resonance (NMR) assignments for the polypeptide backbone of a tetrameric N-terminal fragment

101 pproximately 50% of the amide protons of the polypeptide backbone of Abeta(1-40) resist exchange in a

102 This model places the polypeptide backbone of both the first and third Ca2+-bi

103 of altering the carbohydrate moieties or the polypeptide backbone of GspB.

104 of lactase and phlorizin active sites in the polypeptide backbone of LPH-D1796fs and LPH-Y1473X respe

105 lative rates of exchange of hydrogens of the polypeptide backbone of PE with deuterium atoms from D(2

106 ymerize rapidly at 100 degrees C to give the polypeptide backbone of PNA.

107 e diphosphates leads to fragmentation of the polypeptide backbone of R1.

108 ational coupling pathway, which, through the polypeptide backbone of the beta subunit, physically lin

109 Some positional changes in the polypeptide backbone of the beta6-beta10-beta9 sheet con

110 e K is able to complete the digestion of the polypeptide backbone of the DNA oligonucleotide-linked t

111 rbohydrates based upon the properties of the polypeptide backbone of the maturing substrate.

112 axation parameters of pXqua confirm that the polypeptide backbone of the QUA2 region is more dynamic

113 alone or tethered to D1, indicating that the polypeptide backbone of this part of D2 is highly flexib

114 er enhanced by small (<3 A) movements in the polypeptide backbones of certain antibody CDR loops, by

115 ious study, provide strong evidence that the polypeptide backbones of the head domains form a symmetr

116 led sigma protein is then used to cleave the polypeptide backbones of the RNAP proteins at exposed re

117 proximate twofold symmetry axis relating the polypeptide backbones of these two helix-turn-helix unit

118 onservation of the binding site on the nAChR polypeptide backbone per se.

119 Here we measure intramolecular polypeptide backbone reconfiguration as a way to underst

120 utation at position 82 induces change in two polypeptide backbone regions, 35-41 and 67-68, which may

121 The time scale for ordering of the polypeptide backbone relative to the side chains is a cr

122 Instead, polypeptide backbones sample conformations that are dena

123 nd its digestion with PNGase F resulted in a polypeptide backbone similar in size to salivary CA VI.

124 denaturation and induced alterations in MHC polypeptide backbone structure as determined by circular

125 onsistent with the absence of a well-defined polypeptide backbone structure in this region of the pro

126 , a betabetaalpha protein motif based on the polypeptide backbone structure of a zinc finger domain.

127 the kinetics of amide H/D exchange along the polypeptide backbone suggest that the monomer has a glob

128 ering the active site from a position on the polypeptide backbone that is not utilized in other tyros

129 induced a local conformational change in the polypeptide backbone that resulted in a narrowed S1 subs

130 e marked structural homology of the selectin polypeptide backbones, the selectin EGF surfaces show un

131 lize polypeptides through exclusion from the polypeptide backbone; the inhibition of renaturation/rea

132 allows placement of a variety of probes on a polypeptide backbone, to monitor the behavior of labeled

133 ns such as SCN(-) and I(-) interact with the polypeptide backbone via a hybrid binding site that cons

134 In contrast, the half-life of the polypeptide backbone was 8 h, indicating that palmitoyla

135 The folding status of each segment of the polypeptide backbone was determined from the deuterium l

136 urospora crassa Cu(6)-metallothionein (NcMT) polypeptide backbone was determined using homonuclear, m

137 ely in the nuclear fraction, and size of its polypeptide backbone was the same as that of the cytopla

138 ay influence the conformational options of a polypeptide backbone, we have characterized Pro-->Ala mu

139 eover, slower internal motional modes of the polypeptide backbone were identified by measuring transv

140 m appears to contain "random" buried runs of polypeptide backbone which convert to alpha-helix in the

141 upon the reaction of Thr 66 Ogamma with the polypeptide backbone, which in turn reduces the conjugat

142 ocessively and directionally steps along the polypeptide backbone with a kinetic step size of approxi

143 ministrated clinically, erythropoietin has a polypeptide backbone with complex dishomogeneity in its

144 ider how the position and orientation of the polypeptide backbone (with respect to the DNA) helps to

145 mitted the 3D structure determination of the polypeptide backbone without the substitution and utiliz