ライフサイエンスコーパス: polyploid

1 ccumulated mutation by virtue of their being polyploid.

2 ccales and P. furiosus is suspected of being polyploid.

3 er from mature hepatocytes, which are mostly polyploid.

4 cteria described to date appear to be highly polyploid.

5 tion has not been commonly observed in plant polyploids.

6 d gene expression remolding in the resulting polyploids.

7 series of best practices for SNP calling in polyploids.

8 ge and contribute to evolutionary success of polyploids.

9 olecular mechanisms of meiotic regularity in polyploids.

10 group of C4 species with a high frequency of polyploids.

11 our bioinformatics pipeline is applicable to polyploids.

12 s parental genomes of high-level hybrids and polyploids.

13 liferation and nonadditive quantities in the polyploids.

14 properties such as ecological adaptation by polyploids.

15 le-locus karyotypes are very common, even in polyploids.

16 ossible reason for the success and spread of polyploids.

17 Polyploid AAV vectors can be generated from any AAV sero

18 ) present in each of three sets of 50 mostly polyploid accessions, for four loci, in three PacBio run

19 resence of multiple homologs or homeologs in polyploids affords greater tolerance to mutations that c

20 lineages of plants and animals are typically polyploid, an attribute that may influence their genetic

21 During maturation, they become polyploid and accumulate massive amounts of protein and

22 icate their DNA but fail to divide, becoming polyploid and enlarged.

23 enomes in general, are typically repetitive, polyploid and heterozygous, which complicates genome ass

24 uces transcriptional differences between the polyploid and its diploid progenitors, possibly attenuat

25 unt of niche overlap and breadth between the polyploid and progenitors.

26 me doubling confers distinct advantages to a polyploid and that these advantages allow polyploids to

27 a, but it remains unclear how Sequoia became polyploid and why this lineage overcame an apparent gymn

28 pression has been widely observed in diverse polyploids and comprises at least three possible scenari

29 e rounds of hybrid speciation (homoploid and polyploid) and lay the foundation for a new framework fo

30 omegalic nuclei from Fan1(nd/nd) kidneys are polyploid, and fibroblasts from Fan1(nd/nd) mice become

31 melanogaster subperineurial glia (SPG) to be polyploid, and ploidy is coordinated with brain mass.

32 s are valuable for the evolutionary study of polyploids, and may shed light on studies of hybrid vigo

33 and economical to study the phylogenetics of polyploids, and, in conjunction with recent analytical a

34 al limb shape and tube length, and that most polyploids are distinct or transgressive in at least one

35 ergence and retention of duplicated genes in polyploids are poorly understood.

36 d animal kingdoms specific cell types become polyploid as part of their differentiation programs.

37 posed of diploid sexual and both diploid and polyploid asexual (i.e., apomictic) lineages.

38 rding the distribution of diploid sexual and polyploid asexual taxa across biogeochemical gradients a

39 Polyploid bacteria are common, but the genetic and funct

40 g in the formation of elongated and branched polyploid bacteria with definitive loss of cell division

41 y-partition problem of the reads, called the Polyploid Balanced Optimal Partition model.

42 n is available, the model is extended to the Polyploid Balanced Optimal Partition with Genotype const

43 4 have been inferred to be relatively recent polyploids because they are phylogenetically nested with

44 In mammals, megakaryocytes (MKs) become polyploid before fragmenting into platelets.

45 shable from human embryos at the blastomere, polyploid blastomere, compaction, morula and blastocyst-

46 pecially well suited for identifying SNPs in polyploids, both outbred and inbred, but would tend to b

47 Many plant and animal cells are polyploid, but how these polyploid tissues contribute to

48 By analyzing large spindles of polyploid C. elegans and a related nematode species, we

49 compelling evidence that the alleged recent polyploid C. schulzii is not an autohexaploid derivative

50 Switchgrass (Panicum virgatum), a perennial, polyploid, C4 warm-season grass is among the foremost he

51 The expression levels of duplicated genes in polyploids can show deviation from parental additivity (

52 Polyploid cancer cells exhibit chromosomal instability (

53 ly degraded by acetylated Skp2, resulting in polyploid cell division, genomic instability, and oncoge

54 romotes the diploid-polyploid conversion and polyploid cell growth through the Akt-Skp2 axis.

55 Thus, disrupting genes in polyploid cell lines or when using poorly performing sgR

56 in diploid cells resulted in acquisition of polyploid cell traits.

57 quitination of histone-H2A at lysine-119) in polyploid cell.

58 in UV- and VP-16-treated cells and increases polyploid cells after VP-16 treatment.

59 ntial recognition of autophagy-competent and polyploid cells by the innate and cellular immune system

60 p53-mediated suppression of proliferation of polyploid cells can be averted by increased levels of on

61 Somatic polyploid cells can be mononucleate or multinucleate, an

62 In mammals, the development of polyploid cells can contribute to tissue differentiation

63 Polyploid cells can originate from cell fusion, endorepl

64 end points are preceded by the appearance of polyploid cells caused by the suppression of Aurora kina

65 While most cells maintain a diploid state, polyploid cells exist in many organisms and are particul

66 Polyploid cells have genomes that contain multiples of t

67 w cytometry confirmed a greater frequency of polyploid cells in basal zones of leaf blades, consisten

68 0% in humans, the specialized role played by polyploid cells in liver homeostasis and disease remains

69 igenesis, primarily because cell division in polyploid cells is error-prone and produces aneuploid ce

70 Underreplication of specific regions in polyploid cells is proposed to be due to a slower S phas

71 ocycles, as we find only the M-phase-capable polyploid cells of the papillae and female germline can

72 the formation of tetraploid or higher-order polyploid cells resulting from the culture of human colo

73 tion of Aurora-A in adult tissues results in polyploid cells that display a DNA-damage-like response

74 Megakaryocytes are large, polyploid cells that produce platelets.

75 because Aurora-A-deficient tumors accumulate polyploid cells with limited proliferative potential.

76 ientation of individual chromosomes in large polyploid cells would not hamper reproductive success as

77 ive stress promotes the appearance of highly polyploid cells, and antioxidant-treated NAFLD hepatocyt

78 e mechanisms that lead to the development of polyploid cells, our current state of understanding of h

79 ra-nuclear protein translocation of FoxM1 in polyploid cells, respectively.

80 Polyploid cells, which contain more than two genome copi

81 cation remains unfinished in many Drosophila polyploid cells, which harbor disproportionately fewer c

82 are terminally differentiated, uncultivable polyploid cells, with remarkably elongated and even bran

83 were specifically exposed on the surface of polyploid cells, yet lost upon passage of such cells thr

84 of chromosome structure in both diploid and polyploid cells.

85 aryocytes, as well as an increased number of polyploid cells.

86 from problems with chromosome segregation in polyploid cells.

87 g and functional analysis in post-mitotic or polyploid cells.

88 phology checkpoint to avoid the formation of polyploid cells.

89 ribed changes with respect to development in polyploid cells.

90 Given that mitochondrial genomes are polyploid, cells with advantageous levels of mtDNA mutat

91 ogenetic range of the Campanula rotundifolia polyploid complex.

92 ive isolation among three cytotypes within a polyploid complex.

93 which may slow divergence and speciation in polyploid complexes.

94 od (Sequoia sempervirens) is one of just two polyploid conifer species and the only hexaploid.

95 po pathway effector Yap promotes the diploid-polyploid conversion and polyploid cell growth through t

96 Upland cotton is a model for polyploid crop domestication and transgenic improvement.

97 ng the directional effects of selection in a polyploid crop genome.

98 umber of such gene-based markers is small in polyploid crop plants such as allotetraploid cotton that

99 underpin association genetics studies in the polyploid crop species Brassica napus (oilseed rape).

100 Here we focus our analysis on soybean, a polyploid crop with a highly duplicated genome, relative

101 We demonstrate expVIP's suitability for polyploid crops and evaluate its performance across a ra

102 Understanding the diversification of polyploid crops in the circum-Mediterranean region is a

103 diploid model organisms, are missing in many polyploid crops.

104 ed in powerful reverse genetic approaches in polyploid crops.

105 ic engineering, breeding, and improvement of polyploid crops.

106 uction and for further evolution analysis of polyploid crops.

107 d methods developed herein can benefit other polyploid crops.

108 ision and normal organ development occurs in polyploid, DDR-impaired Drosophila papillar cells.

109 m three diploid cytotypes, their hybrids and polyploid derivatives.

110 The parental genomes of most Andropogoneae polyploids diverged in the Late Miocene coincident with

111 Chloroplast genomes are organized as a polyploid DNA-protein structure called the nucleoid.

112 Selective sweeps were enriched among polyploid duplicates encoding key developmental and phys

113 eltoides forms a monophyletic clade with the polyploid Emmer and Timopheevi wheats, which originated

114 traploid S. viminalis var. Energo genotypes (polyploid Energo [PP-E]; 2n = 4x = 76) with variation in

115 lution of morphological complexity, and some polyploids enjoy a variety of capabilities that transgre

116 ells, S. meliloti differentiates into highly polyploid, enlarged nitrogen-fixing bacteroids.

117 Disentangling the evolutionary histories of polyploids, especially those with high ploidies, can rev

118 croclimate factors may play a larger role in polyploid establishment than previously hypothesized.

119 statistical performances of five additional polyploid estimators of relatedness were also quantified

120 The statistical performances of three polyploid estimators under both ideal and actual conditi

121 hock that occurs following hybridization and polyploid events and may also contribute to uncovering t

122 cation of Brassicaceae species suggests that polyploid events may have conferred higher adaptability

123 a is an ideal model to increase knowledge of polyploid evolution.

124 ggesting that it plays a significant role in polyploid evolution.

125 cilitates investigation of broad patterns of polyploid evolution.

126 ct that is of much importance in view of A-D polyploid formation being key to the evolution of the mo

127 c chromosome number) are known to facilitate polyploid formation.

128 oid parents of T. castellanus, and that this polyploid formed at least three times.

129 eiosis I to meiosis II lead to aneuploid and polyploid gametes, but the regulatory mechanisms control

130 id WGDs and how diploidization affected post-polyploid gene retention.

131 Our study provides insights into polyploid genome evolution and valuable resources for ge

132 ts of the predictability of patterns of post-polyploid genome evolution.

133 reconstructing the multiple haplotypes of a polyploid genome from its sequence reads becomes practic

134 udy the evolutionary dynamics of a large and polyploid genome, specifically the impact of single gene

135 tion, function, and evolution of a large and polyploid genome, the availability of a high-quality seq

136 rs that distinguish subgenome sequences in a polyploid genome.

137 pment of new analyses and views to represent polyploid genomes (of which bread wheat is the primary e

138 However, cultivated mints have complex polyploid genomes and are sterile.

139 Yet computational investigations into polyploid genomes carry great importance, impacting plan

140 chanisms by which the molecular evolution of polyploid genomes establishes genetic architecture under

141 ich is challenging given the large and often polyploid genomes of plants.

142 uences, but assemblies of large, repeat-rich polyploid genomes, such as that of bread wheat, remain f

143 anging from small to gigantic repeat-rich or polyploid genomes.

144 t identical by descent and (iii) assembly of polyploid genomes.

145 Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-

146 Polyploid giant cancer cells (PGCCs) have been observed

147 Polyploid granuloma-resident macrophages formed via modi

148 Each polyploid had at least partial geographic sympatry and a

149 ikelihood estimation framework, HapTree, for polyploid haplotype assembly of an individual genome usi

150 here is an absence of theory and methods for polyploid haplotype reconstruction.

151 re accurate than the recent state-of-the-art polyploid haplotyping algorithms.

152 However, the computational challenge in polyploid haplotyping is much greater than that in diplo

153 This article models the polyploid haplotyping problem as an optimal poly-partiti

154 apping, discovery and application of SNPs in polyploids has been difficult.

155 nderlying a particular trait are reshaped in polyploids has not been experimentally investigated.

156 Difficulties in generating nuclear data for polyploids have impeded phylogenetic study of these grou

157 tral cells differentiate into Tbx3-negative, polyploid hepatocytes, and can replace all hepatocytes a

158 ted levels on BALB/cByJ hepatocytes and also polyploid hepatocytes, might facilitate Plasmodium liver

159 and observed profound, lifelong depletion of polyploid hepatocytes, proving that miR-122 is required

160 observed preference of sporozoites to infect polyploid hepatocytes.

161 rmal postnatal liver development, leading to polyploid hepatocytes.

162 chromosomal variants that originate in young polyploids (here, an intergenomic translocation) may bec

163 We also considered ambiguity in polyploid heterozygote genotyping and developed a weight

164 The endosymbiotic bacteria reside in polyploid host cells as membrane-surrounded vesicles whe

165 r community context and how the emergence of polyploids in populations could also alter the community

166 rs may result in expression nonadditivity in polyploids, including maternal-paternal influence, gene

167 d animal kingdoms specific cell types become polyploid, increasing their DNA content to attain a larg

168 between multiple copies of a basic genome in polyploid individuals, assembly of such data usually res

169 he shift was niche intermediacy in which the polyploid inhabited a geographic range between that of t

170 r to random mutation during radiation of the polyploid into multiple clades and species.

171 which cells decide to skip mitosis to become polyploid is largely undefined.

172 os: (a) The total gene expression level in a polyploid is similar to that of one of its parents (expr

173 at one of the parental subgenomes in ancient polyploids is generally more dominant, having retained m

174 bers of mitotic cells, apoptotic bodies, and polyploid keratinocytes were evident in Aurora-A(-/-) ep

175 from hybridization through evolution at the polyploid level and following cotton domestication.

176 from genome merger through evolution at the polyploid level.

177 stability in diploid apomicts by providing a polyploid-like system for buffering the effects of delet

178 arguments and empirical studies suggest that polyploid lineages may actually have lower speciation ra

179 opulations, contributing to novelty in older polyploid lineages.

180 esponding to either diploid (M. guttatus) or polyploid (M. luteus and M. x robertsii) samples.

181 seems to be the ability to produce a highly polyploid MAC, which then allows for the maintenance of

182 Toll-like receptor (TLR) 2 signal instructs polyploid macrophage fate by inducing replication stress

183 ns that ultimately lead to the production of polyploid megakaryocytes.

184 RhoA/ROCK pathway that has a low activity in polyploid megakaryocytes.

185 rst show that diploids are not preadapted to polyploid meiosis.

186 In marked contrast, diploid and other polyploid members of the complex failed to expand their

187 ter a whole-genome duplication, newly formed polyploids missegregate chromosomes and undergo genetic

188 ed proliferation with an increased number of polyploid mitoses.

189 these cells are indeed capable of generating polyploid MKs, they are not the source of the first plat

190 the presence of a large proportion of highly polyploid mononuclear cells, which are rarely observed i

191 We show that polyploid morphological divergence from the intermediate

192 Yet, polyploids must overcome the meiotic challenge of pairin

193 rphisms consistent with the heterozygous and polyploid nature of the switchgrass genome.

194 ces are understood largely from newly formed polyploids (neopolyploids) that have been grown experime

195 cess leading to the development of elongated polyploid noncultivable nitrogen fixing bacteroids that

196 ion, chromosomal segregation is aberrant and polyploid nuclei are observed.

197 In response to cellular stress, polyploid nuclei diminish and haploid nuclei predominate

198 is, tubular degeneration, and characteristic polyploid nuclei in multiple tissues.

199 cytokinesis may lead to diploid gametes and polyploid offspring.

200 erally by initiating endocycles and becoming polyploid, or by cell fusion.

201 Polyploid organisms are increasingly becoming the target

202 pite many economically important crops being polyploid organisms, the current primer design tools are

203 arguing that it is particularly relevant in polyploid organisms.

204 ry, and highlights the pitfalls of inferring polyploid origins from niche/range alone or combined wit

205 Switchgrass (Panicum virgatum) is a polyploid, outcrossing grass species native to North Ame

206 the fruit fly Drosophila melanogaster, where polyploid ovarian follicle cells amplify genomic regions

207 ore, unlike diploid mitotic divisions, these polyploid papillar divisions are frequently error prone,

208 As it is a self-incompatible polyploid perennial species, breeding elite and stable s

209 Panicum virgatum L. (switchgrass) is a polyploid, perennial grass species that is native to Nor

210 p resolve the ancestry of one of these older polyploids, phylogenetic analyses of multiple population

211 By integrating linkage mapping, polyploid phylogeny and sex-determining region (SDR) in

212 he demographic and evolutionary history of a polyploid plant complex associated with semi-dry habitat

213 the relationship between DNA methylation and polyploid plant domestication remains elusive.

214 complex genomes are being tackled, including polyploid plant genomes.

215 during evolution, the origins of many extant polyploid plant species remain largely unknown.

216 ex (Asteraceae), which comprises diploid and polyploid plants distributed throughout China.

217 Evidence for this mechanism comes from polyploid plants, bacteria, and archaea.

218 ploids (fungi), diploids (most mammals), and polyploids (plants).

219 functionality of dao is highly suited to the polyploid plastid compartment, where it can be used to p

220 tually leads to the formation of diploid and polyploid pollen grains.

221 stress induce the production of diploid and polyploid pollen in Arabidopsis (Arabidopsis thaliana).

222 rsal efficiency of this intein in a natural, polyploid population.

223 ating tetraploid cells can emerge from acute polyploid populations.

224 rchers and plant breeders to unlock the full polyploid potential of wheat.

225 They are produced by large polyploid precursor cells called megakaryocytes.

226 Megakaryocytes also become more polyploid, producing 4-fold more platelets.

227 riate re-initiation of mitosis, uncontrolled polyploid progression, and cell death by mitotic failure

228 ch subgenome dominates within a newly formed polyploid remain poorly understood.

229 erstanding of nonadditive gene expression in polyploids remains limited, a new generation of investig

230 We addressed these issues in a polyploid representative of Hydatellaceae, part of the w

231 and 19.2% genome contraction from the early polyploid, respectively.

232 in environments that pose challenges to the polyploid's diploid progenitors.

233 ccurate SNP yield possible from low-coverage polyploid sequence data.

234 uate the performance of HapTree on simulated polyploid sequencing read data modeled after Illumina se

235 bacteroids are terminally differentiated and polyploid, similar to bacteroids in IRLC legumes.

236 , condensins of the germline nucleus and the polyploid somatic nucleus are composed of different subu

237 ntally altered chromosome arrangement in the polyploid somatic nucleus: multiple copies of homologous

238 esting that unreduced gametes may facilitate polyploid speciation in response to changing environment

239 The highly dormant Lepidium papillosum is a polyploid species and possesses multiple structurally di

240 ccurately identifying transcript isoforms in polyploid species because of the high sequence similarit

241 Here we characterize AS in the polyploid species cotton.

242 presence of CNV and its biological impact in polyploid species has not yet been documented.

243 The sequences among subgenomes in a polyploid species have high similarity, making it diffic

244 Polyploid species have long been thought to be recalcitr

245 fication and in the establishment of nascent polyploid species in wheat.

246 Young polyploid species such as wheat, which was domesticated

247 ether with genome editing, are being used in polyploid species to combine mutations in all copies of

248 pture for discovery of genome variation in a polyploid species with a large, repetitive and heterozyg

249 In polyploid species, altering a trait by random mutagenesi

250 This suggests that, in contrast to other polyploid species, chromosome sorting is context depende

251 In polyploid species, SNP data usually contain a new type o

252 l for developing similar resources for other polyploid species.

253 unique opportunity for studying evolution of polyploid species.

254 e as a general strategy for sequencing other polyploid species.

255 and will enhance our understanding of AS in polyploid species.

256 Despite this, numerous genome-duplicated (polyploid) species persist in nature, indicating early p

257 The polyploid state reduces spontaneous mutation accumulatio

258 in an irreversible, strongly elongated, and polyploid state.

259 proaches to SNP calling, highlighting recent polyploid successes.

260 undancy is more extensive in recently formed polyploids such as wheat, which can now benefit from the

261 have more than two sets of chromosomes are 'polyploid' such as 'triploid' (3n), 'tetraploid' (4n), '

262 Thus far, community-level studies of polyploids suggest an array of outcomes, from no changes

263 related to the large, highly repetitive and polyploid switchgrass genome, to perform genome-wide ass

264 on of F(1) hybrid, and synthetic and natural polyploid T. mirus with the parental diploid species rev

265 H102E, and unique features associated with a polyploid tapetum.

266 In addition, we show that polyploids tend to evolve shorter and wider corolla tube

267 otic isolation was weaker among higher order polyploids than between diploids and tetraploids, and un

268 ing much-needed model systems of established polyploids that have been, and remain to be, recognized.

269 matic polyploidy occurs and how cells become polyploid - the first of these issues being more specula

270 As papillar cells become polyploid, they naturally accumulate broken acentric chr

271 e we evaluate CIN in human cells that become polyploid through an experimentally induced endoreplicat

272 al cell cycle variation wherein cells become polyploid through repeated genome duplication without mi

273 y, BALB/cByJ hepatocytes are more frequently polyploid; thus, their susceptibility converges on the p

274 nd animal cells are polyploid, but how these polyploid tissues contribute to organ growth is not well

275 ly of alternating S and gap phases--produces polyploid tissues.

276 part of the diploidisation process returning polyploids to a diploid-like state over time.

277 a polyploid and that these advantages allow polyploids to thrive in environments that pose challenge

278 olyMarker is available as a ruby BioGem: bio-polyploid-tools.

279 Consequently, polyploid trypanosomes containing 8C equivalent of DNA p

280 damage response and repair gene networks in polyploid tumour cells, enabling them to escape replicat

281 f chromosomal loci in the very large, highly polyploid, uncultivated intestinal symbiont Epulopiscium

282 he phenomenon of genome dominance in ancient polyploids: unique 24nt RNA coverage near genes is great

283 and fibroblasts from Fan1(nd/nd) mice become polyploid upon ICL induction, suggesting that defective

284 These results indicate that polyploid viruses might potentially acquire advantages f

285 In whole-organism polyploids, WGD has been implicated in adaptability and

286 Polyploid wheat (Triticum aestivum) has had a massive in

287 absent in the A-genome diploid donor and in polyploid wheat but is effective when transferred from T

288 With this fully assembled polyploid wheat genome, we identified the causal mutatio

289 enes, together with the large genome size of polyploid wheat, had hindered genomic analyses in this i

290 In polyploid wheat, the diploid-like chromosome pairing is

291 y compared to a pre-validated set of SNPs in polyploid wheat, we were also able to estimate the false

292 ctive when transferred from T. monococcum to polyploid wheat.

293 ength affects final grain size and weight in polyploid wheat.

294 ulate the response of quantitative traits in polyploid wheat; we also argue that functional redundanc

295 Polyploid wheats comprise four species: Triticum turgidu

296 In the polyploid wheats, Triticum aestivum and T. turgidum, the

297 ession to the evolution and domestication of polyploid wheats.

298 the course of domestication and evolution of polyploid wheats.

299 oid gene flow, especially among higher order polyploids, which may slow divergence and speciation in

300 plants on these N + P plots are dominated by polyploids with large GS and a competitive plant strateg