ライフサイエンスコーパス: polysorbate

1 trometry (LC-MS) for the characterization of polysorbates.

2 food grade surface active compounds, namely, Polysorbate 20 (PS20), sodium caseinate (SC), gum Arabic

3 The detergent polysorbate 20 (Tween 20) was used successfully to facil

4 , and quantify the multiple ester species in polysorbate 20 and also to monitor the change of their c

5 polysorbate in the formulation sample, while polysorbate 20 esters were trapped online and then analy

6 the molecular heterogeneity and stability of polysorbate 20 in mAb formulations as polysorbate can gr

7 the characterization and stability study of polysorbate 20 in the presence of mAb formulation sample

8 Polysorbate 20 is a nonionic surfactant commonly used in

9 nto the heterogeneous stability behaviors of polysorbate 20 subspecies in real-time stability samples

10 as developed using elevated temperatures and polysorbate 20, rather than chaotropic and reducing agen

11 loped to analyze the degradation products of polysorbate 20.

12 , agar dilution, broth microdilution without polysorbate 80 (BMD), and the TREK Gram-negative extra M

13 ve bacilli (GNB) by broth microdilution with polysorbate 80 (BMD-T), broth macrodilution (TDS), and t

14 cyanoacrylate) dextran polymers coated with polysorbate 80 (PBCA nanoparticles) to deliver BBB-imper

15 -knockout mice in the presence or absence of polysorbate 80 (PS80) or Kolliphor EL (formerly Cremopho

16 taxel (Taxotere) and its formulation vehicle polysorbate 80 (Tween 80) in human plasma samples is des

17 ric series differences in the two batches of polysorbate 80 and the presence of one compound and thre

18 In addition to the use of Gelucire 44/14 and polysorbate 80 as excipients in drugs, they are also wid

19 port of a project to assess the influence of polysorbate 80 concentrations on the disposition and tox

20 d to measure concentrations of docetaxel and polysorbate 80 in plasma samples in support of a project

21 , magnesium, zinc, potassium, thymidine, and polysorbate 80 levels were tested by BMD and DD.

22 Incorporating polysorbate 80 resulted in 3 twofold and 2 twofold modal

23 the quality controls (QCs) with and without polysorbate 80 supports the use of Escherichia coli stra

24 Detection of docetaxel and polysorbate 80 was performed using tandem MS detection w

25 l polyethylene glycol 1000 succinate (TPGS), Polysorbate 80, and poly(methyl methacrylate) (PMMA) as

26 their formulation vehicles Cremophor EL and polysorbate 80, as well as serum binding proteins on tax

27 ng/ml) and 1.00 microg/ml for docetaxel and polysorbate 80, respectively.

28 tive conditions were 100rpm in water with 2% polysorbate 80, which showed profile differences between

29 be diminished by adding a surfactant, i.e., polysorbate 80.

30 two different batches of Gelucire 44/14 and polysorbate 80.

31 v hydroxypropyl-methylcellulose and 0.1% w/v polysorbate 80; Control, n = 6) for 12 days by oral gava

32 ct of Gattefosse s.a, St Priest, France) and polysorbate 80; these are known to improve solubility of

33 using media supplemented with a surfactant (polysorbate-80, 0.002%).

34 etary emulsifiers, carboxymethylcellulose or polysorbate-80, exacerbated tumor development.

35 ulsifiers, namely carboxymethylcellulose and polysorbate-80, induced low-grade inflammation and obesi

36 % w/v hydroxypropyl-methylcellulose 0.1% w/v polysorbate-80; n = 9), 88 mg( )kg(-1) day(-1) simvastat

37 hapter <797> calls for tryptic soy agar with polysorbate and lecithin (TSApl) for bacteria and malt e

38 The molecular heterogeneity of polysorbate and the interference from proteins and the e

39 In reality, polysorbates are complex mixtures of multiple components

40 The polysorbates are often pictured as polyoxyethylated sorb

41 ity of polysorbate 20 in mAb formulations as polysorbate can gradually degrade in aqueous solution ov

42 Complex synthetic formulations based on polysorbates can be challenging to characterize.

43 ic probe 5-dodecanoylaminofluorescein (DAF), polysorbate concentrations above the critical micelle co

44 o further resolve as well as to identify the polysorbate ester subspecies.

45 We found different polysorbate esters degrade at different rates, and impor

46 omponents of identical molecular mass in the polysorbate formulations have been separated by ion mobi

47 y has been developed for the quantitation of polysorbate in bioprocess samples.

48 mulation matrix make it a challenge to study polysorbate in protein formulations.

49 the first dimension to separate protein and polysorbate in the formulation sample, while polysorbate

50 Following lung injury induced by polysorbate lavage, a higher PEEP (20-24 cm H2O) with LT

51 Following lung injury induced by polysorbate lavage, the APRV group was ventilated with a

52 Following lung injury induced by polysorbate lavage, the LTVV group was ventilated with a

53 Lung injury was induced by polysorbate lavage.

54 oups with surfactant deactivation induced by polysorbate lavage: the LTVV group (n = 5) and the APRV

55 Polysorbates (PS) are widely used as oil-in-water emulsi

56 Rats received polysorbate TW80 (vehicle) or MRE (10, 30, and 90 mg/kg)