ライフサイエンスコーパス: positional information

1 's 'reaction-diffusion' and Lewis Wolpert's 'positional information'.

2 model systematically combining sequence and positional information.

3 each cell type that arises independently of positional information.

4 hat integrates neural and anterior-posterior positional information.

5 , which involves gradual regaining of normal positional information.

6 linkage map that incorporates sequence-based positional information.

7 that thalamic axons indeed use intracortical positional information.

8 switch fate when exposed to a new source of positional information.

9 phase of the cell cycle in response to local positional information.

10 uration, inadequate for the establishment of positional information.

11 thways for providing cells with temporal and positional information.

12 or that is suitable for the specification of positional information.

13 s; and that also incorporates sequence-based positional information.

14 neural crest-derived mesenchymal cells with positional information.

15 a central role in generating left-right (LR) positional information.

16 ique direct mechanism through which to relay positional information.

17 regulatory network predictions based on gene positional information.

18 cell shape and need not reflect fine-grained positional information.

19 or edges; within A its concentration confers positional information.

20 iorly, suggesting that egl-27 influences A/P positional information.

21 l identity, consistent with muscle harboring positional information.

22 an effort to identify components of maternal positional information.

23 e, but has been restricted to providing only positional information.

24 nic development and regeneration is based on positional information.

25 molecules whose concentration could provide positional information.

26 the different axes to obtain directional and positional information.

27 g to maximize the accuracy of gradient-based positional information.

28 atially varying concentrations and so encode positional information.

29 how Hox-TALE interactions evolved to provide positional information.

30 leaves provide a unique opportunity to study positional information.

31 low cytometry, while also gathering cellular positional information.

32 ique role for Rargb in conferring left-right positional information.

33 nterior-posterior axis of the embryo provide positional information.

34 e nuclear Bcd concentrations and Bcd-encoded positional information.

35 genitalia must integrate sexual identity and positional information.

36 fluctuations that contribute to the error in positional information.

37 ay an important role in the establishment of positional information.

38 This database provides positional information about human BAC clones from the R

39 Orientational as well as positional information about potential functional groups

40 others act at the time of contact, providing positional information about the appropriateness of targ

41 tissue has been associated with transferring positional information across tissue boundaries.

42 ng the SMC division, and is not specified by positional information acting on daughter cells after co

43 ain protein Hex, an early marker of anterior positional information, acts as a transcriptional repres

44 tervals [-1000, 0], [-500, 0] and [-250, 0], positional information aided motif prediction less and l

45 members suggest that each subclass specifies positional information along independent retinal axes.

46 shed after amputation, a dynamic gradient of positional information along the proximodistal (PD) axis

47 less (Wg) and Decapentaplegic (Dpp) organize positional information along the proximodistal (PD) axis

48 to alter the interpretation of gradients of positional information along the proximodistal axis of t

49 ly requires the generation and perception of positional information along the radial (adaxial versus

50 that explains the potential link between D-V positional information and apical ridge formation, and d

51 recruitment zone to reset proximodistal (PD) positional information and assemble the blastema.

52 Thus, positional information and cell motility underlie the di

53 ion may pattern the neural tube, integrating positional information and cell type differentiation.

54 draft genome sequence in providing accurate positional information and detailed characterization of

55 eries the e!Ensembl BioMart server to obtain positional information and discovers homology relations

56 that may underlie these QTL on the basis of positional information and functional arguments.

57 Selection must therefore act on positional information and its apportionment, rather tha

58 among a broad range of taxa believed to gain positional information and navigate using the earth's ma

59 air cells and non-hair cells, in response to positional information and the activity of the homoeodom

60 epend both on patterning genes, which assign positional information, and on genes that regulate mecha

61 ptors and ephrins constitute domain-specific positional information, and the spatially accurate recep

62 suggests that establishing and interpreting positional information are not independent processes in

63 cues on cell fate has shown that domains of positional information are organised with well-defined b

64 s other markers indicates the involvement of positional information as a primary determinant in regen

65 nd instead results from an interplay between positional information assigned during early limb bud de

66 To determine how LR positional information becomes ;translated' into anatomi

67 T protein provides a mechanism for signaling positional information between cell layers of the root.

68 exts, a locally produced morphogen specifies positional information by forming a concentration gradie

69 gen gradients provide embryonic tissues with positional information by inducing target genes at diffe

70 ical view of development, a cell can acquire positional information by reading the local concentratio

71 it, which prevents the collection of dynamic positional information by traditional optical methods.

72 Our studies suggest that positional information can be stored transiently in the

73 Recent results indicate that positional information can be transmitted through interc

74 ggesting that other developmental cues, like positional information, can progressively over-ride the

75 Here, we study the mechanisms by which positional information conveyed by signaling pathways an

76 lation, cells in both germ layers read their positional information coordinately from a single morpho

77 e associated with loss of ability to express positional information cues that are required for normal

78 the first example of a system that generates positional information de novo.

79 Positional information derived from local morphogen conc

80 related to L1 and neurofascin, can transmit positional information directly to ankyrin and thereby p

81 tein patterns are established, and how their positional information directs downstream processes.

82 entration gradient appropriate for conveying positional information during cortical axon guidance in

83 One way in which cells acquire positional information during embryonic development is b

84 ion in which cellular activity feeds back on positional information encoded by gradients, analogous t

85 esponsible for the initial interpretation of positional information encoded by maternal gradients.

86 ms, but it also relies on the structural and positional information encoded in extracellular matrices

87 nd Ds expression provide partially redundant positional information essential for specifying the pola

88 An important unresolved question is how positional information established by these morphogen gr

89 Concurrently, positional information established principally by the ve

90 with there being a gradient of Bmp-dependent positional information extending throughout the entire n

91 We identified a gene, pom1, that provides positional information for both growth and division in S

92 opment to directly shape tissues, to provide positional information for cell fate decisions and to en

93 n addition, we show the capability to obtain positional information for modifications such as trimeth

94 rces is a novel perspective on the source of positional information for neuronal specification in the

95 photoreceptor axon target fields and provide positional information for photoreceptor axon guidance.

96 e detection relies on accurate annotation of positional information for polyA tails added posttranscr

97 The use of the MinD/ParA family to provide positional information for spatial organization continue

98 ved system of extracellular signals provides positional information for the allocation of embryonic c

99 n follicle cells, which provide dorsoventral positional information for the embryo.

100 ressions of Eph-ephrins are known to provide positional information for the formation of topographic

101 ion, and nucleoid occlusion, indicating that positional information for the future pole is independen

102 identify a protein, PodJ, that provides the positional information for the polar localization of bot

103 control of regulatory elements that provide positional information for the regional specification of

104 d from the 3' end to provide high-resolution positional information for the RNA polymerases.

105 sulting asymmetry in the cell wall serves as positional information for the underlying cortex to init

106 embryo, but exactly how these factors act as positional information for this patterning is not yet fu

107 Using positional information from a patient with a 21-kb delet

108 organizes protein similarity and genetic map positional information from diverse sources in the publi

109 In Drosophila, positional information from genes important in anteropos

110 Coupling this information with positional information from high throughput mapping prog

111 ) signaling proteins are thought to transmit positional information from surface guidance cues to the

112 The incorporated positional information from the alignments and PE reads

113 expression provide spatial signals that link positional information from the anterior-posterior patte

114 e the first evidence that they [eels] derive positional information from the Earth's magnetic field"

115 To test the hypothesis that lobsters derive positional information from the Earth's magnetic field,

116 ion and, consistent with a role in conveying positional information from the egg chamber to the embry

117 n the vertebrate embryo requires transfer of positional information from the node to the periphery, r

118 activities is essential for transfer of L-R positional information from the node.

119 into muscular and non-muscular tissue using positional information from the surrounding tissue.

120 In addition, sea turtles derive positional information from two magnetic elements (incli

121 he Drosophila embryo requires extraembryonic positional information generated during oogenesis.

122 stem of extracellular proteins to generate a positional information gradient.

123 We discuss how such general relativistic positional information (GRPI) can guide systems-level ap

124 y for contraction, but also as the source of positional information guiding regeneration.

125 In planarians, positional information has been identified from study of

126 In the regenerating amphibian limb, positional information has traditionally been considered

127 anscription factors play a role in providing positional information important for topographic mapping

128 How morphogens convey positional information in a developing embryo, when sign

129 noise, allows the pom1p gradient to specify positional information in a robust manner.

130 he BMP family, is a morphogen that specifies positional information in Drosophila wing precursors.

131 by MinE underlies the dynamic processing of positional information in E. coli to identify precisely

132 rinciples similar to those used to establish positional information in embryonic patterning are also

133 Homeobox genes convey positional information in embryos and their role in patt

134 This process, utilizing positional information in existing tissue at unpredictab

135 cell morphogenesis and the establishment of positional information in fission yeast.

136 n accuracy suggests that ChloroP uses little positional information in its decision-making; an unexpe

137 present evidence that kni and knrl link A/P positional information in larval wing imaginal discs to

138 ntribute to pattern formation by determining positional information in morphogenetic fields.

139 The lack of BCs and positional information in other cells is therefore the m

140 e to patch-clamp studies, the maintenance of positional information in single-channel measurements, r

141 dissect the molecular mechanisms conferring positional information in skeletal muscles, we character

142 Previous studies have demonstrated roles for positional information in specification of daughter cell

143 Pax2 protein, demonstrating that it receives positional information in the absence of a developing pr

144 asymmetry can be explained by differences in positional information in the body column tissue that ev

145 n of these proteins implies the existence of positional information in the cell, but how this informa

146 istinct cortical signaling centers establish positional information in the cortical primordium and re

147 ly a subset of the elements which respond to positional information in the developing heart tube.

148 r tyrosine kinases and their ligands provide positional information in the developing visual system.

149 Positional information in the dorsoventral axis of the D

150 ich responds in a unique way to gradients of positional information in the early Drosophila embryo.

151 rganization of the larval disc originates as positional information in the embryo, thus providing a c

152 PHAVOLUTA genes in the perception of radial positional information in the leaf primordium.

153 r candidate regulators of anterior-posterior positional information in the limb bud, including HoxB8

154 s suggest that GATA3 expression may maintain positional information in the maculae during sensory reg

155 cold-perceived gravistimulation by providing positional information in the pulvini prior to the redis

156 ling cascade that establishes dorsal-ventral positional information in the retina and controls the fo

157 These results suggest that positional information in the retina and the opsin ident

158 us deletions (HODs), have provided important positional information in the search for cancer-causing

159 reasing efficiency with which observers used positional information in the stimulus.

160 im1-independent role in the establishment of positional information in the trunk.

161 early prestalk message synthesis depends on positional information, in contrast to the establishment

162 n cardiac organogenesis, growth control, and positional information, including the direction of cardi

163 matrix and chemokine provides the necessary positional information independent of a soluble spatial

164 How positional information instructs adult tissue maintenanc

165 hat the anatomical locus at which motion and positional information interact is area V5/MT rather tha

166 ffusion and gene expression regulation shape positional information into an appropriate profile with

167 how groups of cells recognize and translate positional information into morphogenetic movement remai

168 of biosorter data, however, do not integrate positional information into their analysis and data visu

169 s in regions tested express PCGs, suggesting positional information is a major feature of muscle.

170 The question of how positional information is assigned in floral meristems i

171 As multicellular organisms grow, positional information is continually needed to regulate

172 Positional information is crucial for regeneration, but

173 dd to a growing body of evidence that radial positional information is important in meristem formatio

174 ression of Xtmyf-5 expression, implying that positional information is integrated at this site.

175 In addition, positional information is integrated with temporal cues

176 in contributing to heart formation, but how positional information is integrated with this pathway t

177 In the nevermind (nev) mutant, D-V positional information is not maintained by dorsonasal r

178 Positional information is pivotal for establishing devel

179 nt evidence that, in Escherichia coli, polar positional information is present at midcell independent

180 Throughout mitosis the PPBs positional information is preserved by factors that cont

181 This positional information is relayed in the extracellular s

182 Positional information is required for animal regenerati

183 bryo variability, but that this noise in the positional information is strongly decreased ('filtered'

184 Interpretation of positional information is thought to rely on direct, con

185 No positional information is used in the count, but it has

186 s suggest that the ability of MinCD to sense positional information is utilized during sporulation to

187 hat has remained unanswered is how does this positional information lead to the correct spatial activ

188 nalytical platform for the quantification of positional information ("longitudinal profiling") of C.

189 ggesting that IcsA recognition of this polar positional information may influence cell division.

190 rams for identifying sequence motifs exploit positional information, most of them model it only impli

191 During vertebrate limb development, positional information must be specified along three dis

192 f stomata and bulliform cells, implying that positional information must direct the differentiation p

193 ed in setting up morphogenetic boundaries of positional information necessary for controlling cell sp

194 oc locus to mouse chromosome 16 provides the positional information necessary to identify the candida

195 The Hox genes cooperate in providing positional information needed for spatial and temporal p

196 endent regenerative response indicative of a positional information network.

197 We have exploited the positional information obtained from SPFI to develop a m

198 This provides a genetic code to define positional information of any ectoderm sample along the

199 evelopment in detail, including temporal and positional information of organ initiation.

200 ivision zone, translating and preserving the positional information of the PPB by maintaining downstr

201 Positional information of this gradient is transmitted t

202 he proprioceptive system provides continuous positional information on the limbs and body to the thal

203 and chemical sequencing were used to provide positional information on the modifications to the enzym

204 ronal G alpha(s) pathway transduces critical positional information onto the core G alpha(q) pathway

205 By removing positional information, our simpler methods allow us to

206 AX pathway modulates TKV signaling to create positional information over the embryonic ectoderm.

207 c and normal blastemas, and the diversity of positional information provided by blastema cells derive

208 ntation stripes, whereby enhancers integrate positional information provided by broadly distributed a

209 epidermal patterning relies in many cases on positional information provided by cell-cell communicati

210 not known how progenitor cells interpret the positional information provided by inducing signals or h

211 During development of the early neural tube, positional information provided by signaling gradients i

212 d within the developing kidney, and that any positional information provided by the mesenchymal expre

213 Our results demonstrate that the positional information provided by the wt Bcd gradient p

214 roposes that epidermal patterning depends on positional information rather than lineage relationships

215 We propose that the positional information received by a cell at a particula

216 These findings indicate that polar positional information recognized by IcsA depends on one

217 Escherichia coli, the establishment of polar positional information recognized by IcsA requires the a

218 thways for polar cell envelope synthesis and positional information recognized by polar proteins.

219 ions suggest the intriguing possibility that positional information regulates convergence and extensi

220 We also provide evidence that positional information regulating Fat action is provided

221 pattern is defined during embryogenesis and positional information remains active in the root until

222 However, the nature and the origin of positional information remains elusive.

223 n factors expressed in gut mesenchyme convey positional information required for anterior-posterior p

224 e continuous generation or interpretation of positional information required for epidermal specificat

225 The positional information required for such migratory behav

226 m, some of these genes are likely to control positional information required for the sagittal organiz

227 ar auxin transport, but how this impacts the positional information required to establish this tissue

228 To understand the true source of the positional information responsible for limiting Tbx2, Tb

229 Based on this positional information, roughly one-third of the genes a

230 A rigorous statistical analysis showed that positional information significantly improved the predic

231 tissue turnover, providing a model for adult positional information studies.

232 ogress zone) undergo a progressive change in positional information such that their specification is

233 nctions, act more globally to provide graded positional information that can be interpreted by respon

234 ogenic precursor cells must be responding to positional information that controls nephrogenic fate.

235 nstrate that homeotic selector genes provide positional information that determines the anteroposteri

236 haps via diffusion, to yield the gradient of positional information that determines the embryonic dor

237 ete sites that are specified by pre-existing positional information that governs the development of w

238 an epithelium, tricellular junctions encode positional information that helps orient mitotic spindle

239 of activity gradients of BMP, which provide positional information that influences cell fates.

240 mount importance for hindbrain patterning is positional information that is laid down along the rostr

241 pecification in the root epidermis relies on positional information that is organised in stable domai

242 st their functions by interpreting the local positional information that is programmed into the RPC l

243 The nature of the positional information that leads to the proper localiza

244 ical Wnt, and retinoic acid signals generate positional information that leads to the restricted expr

245 ed signals, known as morphogens, provide the positional information that organizes gene expression an

246 suggest that LGN participates in setting up positional information through a signaling cascade.

247 nar polarity in the eye: first in setting up positional information through the production of a plana

248 we propose that the Dorsal gradient supplies positional information throughout nuclear cycles 10-14,

249 nteraction between Otx2 and Gbx2 establishes positional information thus providing a general mechanis

250 l transcription factor Bicoid (Bcd) provides positional information to activate target genes at diffe

251 Morphogen gradients, which provide positional information to cells in a developing tissue,

252 We used positional information to clone IAR1, which encodes a no

253 We used positional information to determine that one ibr5 suppre

254 We used positional information to determine that the gene defect

255 , they provide a novel mechanism linking Hox positional information to differences in neuronal archit

256 med-pbx functions as a central integrator of positional information to drive patterning of regenerati

257 s proceeds via the correct interpretation of positional information to establish boundaries that sepa

258 tinal determination gene expression to relay positional information to eye target genes, because the

259 y important that signaling gradients provide positional information to govern morphogenesis of multic

260 he extracellular matrix (ECM) provides local positional information to guide motoneuron axons toward

261 fibroblasts and highlights the importance of positional information to instruct pattern formation dur

262 proteins and the bacterial nucleoid provide positional information to negatively regulate cytokinesi

263 f sprouts, a location suitable for conveying positional information to neighboring ECs.

264 this mechanism may provide both A-P and D-V positional information to neuronal precursors located wi

265 onment, much like signaling molecules convey positional information to organize embryonic tissues.

266 ic gap gene expression, which in turn convey positional information to pair-rule and segment-polarity

267 gen gradient, has been hypothesized to carry positional information to pattern tissues.

268 ecture is not a default state but depends on positional information to precisely coordinate patterns

269 center that utilizes an existing network of positional information to regulate patterning during ske

270 In the map step, an animal derives positional information to select a direction, whereas in

271 ne membrane, provides structural support and positional information to the embryo.

272 m the pre-patterned ectoderm, which provides positional information to the underlying cardiac mesoder

273 imo-distally oriented subdomains that convey positional information to these developing tissues.

274 Correct radial patterning depends on the positional information transmitted through limited SHR i

275 ferative rates, Hox gene expression provides positional information utilized in producing domain-spec

276 mbrane protein localization data by deriving positional information via surface fitting and combining

277 hese expression levels thus form a code for "positional information." We show how to measure this inf

278 A-GLAM's predictions with and without positional information were compared on two human TFBS d

279 remain biophysically interpretable and hold positional information where experiment and model disagr

280 anar environments, place cells provide focal positional information, whereas grid cells supply odomet

281 Bacteria specify positional information, which determines where cell divi

282 osing the ctenophore adult body plan possess positional information, which is utilized to reconstruct

283 n the absence of differentiation signals use positional information, while cells that divide late aft

284 The integration of positional information with gene expression data allowed

285 nd non-hair cells is dependent on domains of positional information with strict boundaries.

286 membrane and small GTPases as integrators of positional information with the activities of the domain

287 To understand how positional information within an organism specifies patt

288 membrane skeleton behaves as a transducer of positional information within cells.

289 ng lbl1, rld1 and the yabby genes integrates positional information within the SAM, and leads to adax

290 Morphogen gradients provide embryos with positional information, yet how they form is not underst