ライフサイエンスコーパス: positive-strand RNA virus

1 e largest replicase polyprotein of any known positive-strand RNA virus.

2 fling of viral envelope genes to attenuate a positive-strand RNA virus.

3 , that are conserved among orthologs of many positive-strand RNA viruses.

4 lex assembly for BMV, and possibly for other positive-strand RNA viruses.

5 resents a critical step in the life cycle of positive-strand RNA viruses.

6 ember of the Nodaviridae, a family of small, positive-strand RNA viruses.

7 aled unexpected similarities with virions of positive-strand RNA viruses.

8 cellular membranes is a universal feature of positive-strand RNA viruses.

9 olved during infection and disease caused by positive-strand RNA viruses.

10 ication complexes (RCs), by analogy to other positive-strand RNA viruses.

11 , similar to structures found for many other positive-strand RNA viruses.

12 egral membrane replicase proteins from other positive-strand RNA viruses.

13 havirus-like superfamily of animal and plant positive-strand RNA viruses.

14 phaviruses are a well-characterized group of positive-strand RNA viruses.

15 en that belongs to the Potyviridae family of positive-strand RNA viruses.

16 ar membranes are critical for replication of positive-strand RNA viruses.

17 potently facilitate replication of specific positive-strand RNA viruses.

18 the mechanisms underlying the replication of positive-strand RNA viruses.

19 to develop nucleoside analogs against other positive-strand RNA viruses.

20 ity of TRIM56's antiviral activities against positive-strand RNA viruses.

21 olymerase (BVDV RdRp) and RdRps from related positive-strand RNA viruses.

22 -shaping machinery among different groups of positive-strand RNA viruses.

23 for the production of viral small RNAs from positive-strand RNA viruses.

24 rug design and provide a precedent for other positive-strand RNA viruses.

25 NA genomes and the RNA genomes of many other positive-strand RNA viruses.

26 n may be a general replication mechanism for positive stranded RNA viruses.

27 the RNA-dependent RNA polymerases of diverse positive-stranded RNA viruses.

28 ts is the first such demonstration among all positive-stranded RNA viruses.

29 ntial permissivity to replication of several positive-stranded RNA viruses.

30 matic infections, also contained one or more positive-strand RNA viruses (Aichi virus, astrovirus, or

31 Dengue virus is a positive-strand RNA virus and a member of the genus Flav

32 Bovine viral diarrhea virus (BVDV) is a positive-strand RNA virus and a member of the genus Pest

33 Poliovirus is a positive-strand RNA virus and the prototypical member of

34 iew, we focus on picornaviruses, a family of positive-strand RNA viruses, and discuss the mechanisms

35 s and factors involved in the replication of positive stranded RNA viruses are still unclear.

36 Plant positive-strand (+)RNA viruses are intracellular infecti

37 Self-amplifying messenger RNA (mRNA) of positive-strand RNA viruses are effective vectors for in

38 Positive-strand RNA viruses are known to rearrange the e

39 Viral replicases of many positive-strand RNA viruses are membrane-bound complexes

40 Although helicases encoded by positive-strand RNA viruses are necessary for RNA genome

41 Positive-strand RNA viruses are the largest virus class

42 All positive-strand RNA viruses assemble their RNA replicati

43 replication of human rhinovirus 2 (HRV2), a positive-stranded RNA virus belonging to the Picornaviri

44 we used the ability of the higher eukaryotic positive-strand RNA virus brome mosaic virus (BMV) to re

45 Like many positive-strand RNA viruses, brome mosaic virus (BMV) RN

46 Positive-strand RNA viruses build extensive membranous r

47 cludes replication enzymes commonly found in positive-strand RNA viruses, but also a set of RNA-proce

48 This arthropod-borne positive-strand RNA virus causes acute and fatal encepha

49 The nidoviruses are an order of positive-stranded RNA viruses, comprising coronaviruses

50 es with either DEN or Sindbis virus, another positive-strand RNA virus, confirmed the early vs late n

51 Many positive-stranded RNA viruses contain short, single-stra

52 However, none of the positive-strand RNA viruses could be causally associated

53 As a positive-strand RNA virus, dengue virus relies on the ho

54 of virus replication complexes for all known positive-strand RNA viruses depends on the extensive rem

55 Infection with many positive-strand RNA viruses dramatically remodels cellul

56 Notably, for a range of positive-strand RNA viruses embodying many major differe

57 iridae and Potyviridae families of the plant positive-strand RNA viruses encode one or two papain-lik

58 Brome mosaic virus (BMV), a positive-strand RNA virus, encodes two replication prote

59 ember of the alphavirus-like super-family of positive-strand RNA viruses, encodes two proteins requir

60 member of the alphavirus-like superfamily of positive-strand RNA viruses, encodes two proteins, 1a an

61 Positive-strand RNA viruses encompass more than one-thir

62 Mammalian positive-stranded RNA viruses establishing persistence t

63 s, members of the Arteriviridae (a family of positive-stranded RNA viruses) express their replicase p

64 Genomes of positive-strand RNA viruses fold into high-order RNA str

65 somal frameshifting (-1 PRF) is used by many positive-strand RNA viruses for translation of required

66 sly that replication complexes of some other positive-strand RNA viruses form on membrane invaginatio

67 astructural features with RNA replication of positive-strand RNA viruses from other families.

68 Positive-strand RNA viruses generally replicate in large

69 Many positive-strand RNA viruses generate 3'-coterminal subge

70 Positive-strand RNA virus genome replication is invariab

71 Positive-strand RNA virus genome replication occurs in m

72 Positive-strand RNA virus genomes are substrates for tra

73 Positive-strand RNA virus genomes are translated into po

74 The 5'-untranslated region of positive-strand RNA viruses harbors many cis-acting RNA

75 In the absence of a 5' cap, plant positive-strand RNA viruses have evolved a number of dif

76 As a positive-strand RNA virus, hepatitis E virus (HEV) produ

77 Like most positive-strand RNA viruses, hepatitis C virus (HCV) is

78 Like other positive-strand RNA viruses, hepatitis C virus (HCV) is

79 on protein 1a of brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

80 Brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

81 Brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

82 Brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

83 Brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

84 in of human noroviruses (HuNoVs), a group of positive-strand RNA viruses in the Caliciviridae family

85 Positive-strand RNA viruses include a large number of hu

86 Replication by many positive-strand RNA viruses includes genomic RNA amplifi

87 eral unique features not found previously in positive-strand RNA viruses, including the fact that it

88 s, TRIM56 is a restriction factor of several positive-strand RNA viruses, including three members of

89 iven translation, which is operative in many positive-stranded RNA viruses, including all picornaviru

90 antibody staining in double-stranded DNA and positive-strand RNA virus infections but not in negative

91 This positive strand RNA virus is remarkably efficient at est

92 This positive-strand RNA virus is remarkably efficient at est

93 The replication of positive-strand RNA viruses is a complex multi-step proc

94 RNA replication of all positive-strand RNA viruses is closely associated with i

95 A-dependent RNA polymerase (RdRp) encoded by positive-strand RNA viruses is critical to the replicati

96 Replication of all positive-strand RNA viruses is intimately associated wit

97 One characteristic of all positive-strand RNA viruses is the necessity to assemble

98 l to the replication of poliovirus and other positive-strand RNA viruses is the virally encoded RNA-d

99 protein processing of dengue virus type 2, a positive strand RNA virus, is carried out by the host si

100 Hepatitis C virus (HCV), a positive-strand RNA virus, is the major infectious agent

101 ral RNA progeny in infected cells of several positive-strand RNA viruses, is initially inactive.

102 RNAs of many positive strand RNA viruses lack a 5' cap structure and

103 on protein 1a of brome mosaic virus (BMV), a positive-strand RNA virus, localizes to the cytoplasmic

104 for the involvement of host phospholipids in positive-strand RNA virus membrane-specific targeting.

105 These positive-strand RNA viruses might be direct ancestors of

106 Replication of positive-strand RNA viruses occurs in tight association

107 cation of tomato bushy stunt virus (TBSV), a positive-strand RNA virus of plants.

108 lication, a widely conserved mechanism among positive-strand RNA viruses of diverse origin.

109 All positive-strand RNA viruses of eukaryotes studied assemb

110 cids are conserved across all polymerases of positive-strand RNA viruses of eukaryotes.

111 mechanism that appears to be conserved among positive-strand RNA viruses of plants (this study), anim

112 The majority of positive-strand RNA viruses of plants replicate and sele

113 Brome mosaic virus, a tripartite positive-stranded RNA virus of plants, was used for the

114 ts in brome mosaic virus (BMV), a tripartite positive-stranded RNA virus of plants.

115 Bovine viral diarrhea virus (BVDV) is a positive-stranded RNA virus of the Flaviviridae family.

116 Positive-stranded RNA viruses of plants use their RNAs a

117 a means of solving the "problem," common to positive strand RNA viruses, of competition between ribo

118 The coat protein of positive-stranded RNA viruses often contains a positivel

119 bditis elegans and its natural pathogen, the positive-strand RNA virus Orsay, have recently emerged a

120 bditis elegans and its natural pathogen, the positive-strand RNA virus Orsay, have recently emerged a

121 avirus-like superfamily, as well as in other positive-strand RNA viruses pathogenic to humans (e.g.,

122 (MeV) uses tissue-specific nectin-4, and the positive-strand RNA virus poliovirus uses nectin-like 5

123 By using a positive-strand RNA virus, porcine reproductive and resp

124 Comparison with other positive-strand RNA viruses producing multiple subgenomi

125 ing residues that are highly conserved among positive-strand RNA virus RdRPs.

126 We studied the Orsay virus, a positive-strand RNA virus related to Nodaviridae and the

127 Positive strand RNA viruses replicate via a virally enco

128 imilar to animal viruses, the abundant plant positive-strand RNA viruses replicate in infected cells

129 All positive-strand RNA viruses replicate their genomes in a

130 Positive-strand RNA viruses replicate their genomes on i

131 Positive-strand RNA viruses replicate their genomes on m

132 tive-strand RNA viruses, similarly to animal positive-strand RNA viruses, replicate in membrane-bound

133 Rubella virus (RUBV), a positive-strand RNA virus, replicates its RNA within mem

134 esults provide new mechanistic insights into positive-strand RNA virus replication compartment struct

135 Positive-strand RNA virus replication complexes are univ

136 ular membrane rearrangements associated with positive-strand RNA virus replication in cells.

137 Biochemical studies suggest that positive-strand RNA virus replication involves host as w

138 ization of host cell membranes essential for positive-strand RNA virus replication should provide ins

139 mosaic virus (BMV) has served as a model for positive-strand RNA virus replication, recombination, an

140 ed functions required for different steps of positive-strand RNA virus replication.

141 The mechanisms that direct positive-stranded RNA virus replication complexes to pla

142 Like other positive-strand RNA viruses, replication of hepatitis C

143 Positive-strand RNA viruses represent a major class of h

144 rabidopsis thaliana defense against distinct positive-strand RNA viruses requires production of virus

145 Positive-strand RNA viruses reshape the intracellular me

146 ture-function relationships and suggest that positive-strand RNA viruses retain a unique palm domain-

147 The universal membrane association of positive-strand RNA virus RNA replication complexes is i

148 Positive-strand RNA virus RNA replication is invariably

149 All well-characterized positive-strand RNA viruses[(+)RNA viruses] induce the f

150 us (HAV) and hepatitis C virus (HCV) are two positive-strand RNA viruses sharing a similar biology, b

151 Plant positive-strand RNA viruses, similarly to animal positiv

152 During infection, positive-strand RNA viruses subvert cellular machinery i

153 Positive-strand RNA viruses such as poliovirus replicate

154 Both positive-strand RNA virus supergroups, coronaviruses and

155 Brome mosaic bromovirus (BMV), a positive-stranded RNA virus, supports both homologous an

156 nternational Herpesvirus Workshop (IHW), the Positive-Strand RNA Virus Symposium (PSR), and the Gordo

157 Rubivirus genus in the Togaviridae family of positive-strand RNA viruses, synthesizes a single subgen

158 Flock House virus (FHV; Nodaviridae) is a positive-strand RNA virus that encapsidates a bipartite

159 Mouse hepatitis virus (MHV) is a 31-kb positive-strand RNA virus that is replicated in the cyto

160 Hepatitis C virus (HCV) is a positive-strand RNA virus that primarily infects human h

161 Hepatitis C virus (HCV) is a positive-strand RNA virus that replicates exclusively in

162 ncephalitis virus (WEEV) are arthropod-borne positive-strand RNA viruses that are capable of causing

163 In contrast to other positive-strand RNA viruses that block IFN induction by

164 Alphaviruses are positive-strand RNA viruses that can mediate efficient c

165 RS-CoV), is a member of this large family of positive-strand RNA viruses that cause a spectrum of dis

166 Flaviviruses are insect-borne, positive-strand RNA viruses that have been disseminated

167 rnaviridae are a large and diverse family of positive-strand RNA viruses that includes hepatitis A vi

168 viruses (DENV) comprise a family of related positive-strand RNA viruses that infect up to 100 millio

169 our findings suggest the existence of novel positive-strand RNA viruses that probably replicate in h

170 Poliovirus, like all positive-strand RNA viruses that replicate in the cytopl

171 Coronaviruses are positive-strand RNA viruses that translate their genome

172 Hepatitis C virus (HCV) is the only known positive-stranded RNA virus that causes persistent lifel

173 Hepatitis C virus (HCV) is a positive-stranded RNA virus that causes severe liver dis

174 West Nile virus (WNV) is an enveloped positive-stranded RNA virus that has emerged over the pa

175 Arteriviruses are economically important positive-stranded RNA viruses that encode an ovarian tum

176 Unlike its antiviral actions against positive-strand RNA viruses, the anti-influenza virus ac

177 Positive-strand RNA viruses, the largest genetic class o

178 iral RNA as a template during replication of positive-stranded (+)RNA viruses, the RNA also has cruci

179 In the case of positive-strand RNA viruses, this represents a particula

180 emonstrate a potential novel mechanism for a positive-stranded RNA virus to regulate viral translatio

181 Similar to other positive-strand RNA viruses, tombusviruses are replicate

182 The genomes of positive-strand RNA viruses undergo conformational shift

183 Genomes of positive (+)-strand RNA viruses use cis-acting signals t

184 Brome mosaic virus (BMV) is a tripartite positive-strand RNA virus used to study the requirements

185 Positive-strand RNA viruses utilize various subcellular

186 irus, poliovirus, and hepatitis C virus, all positive-strand RNA viruses, utilize the maturation of a

187 wn-regulate complementary RNA synthesis of a positive-strand RNA virus via an RNA-RNA interaction.

188 mato bushy stunt virus (TBSV), a small model positive-stranded RNA virus, we overexpressed 5,500 yeas

189 pendent RNA polymerase (RdRp), a hallmark of positive-strand RNA viruses, were identified in two cont

190 The Hepatitis C virus is a positive-stranded RNA virus which is the causal agent fo

191 Replication of positive-stranded RNA viruses, which are major pathogens

192 Brome mosaic virus (BMV) is a model positive-strand RNA virus whose replication has been stu

193 Brome mosaic virus (BMV) is a representative positive-strand RNA virus whose RNA replication, gene ex

194 Hepatitis C virus (HCV) is a positive strand RNA virus with a narrow host and tissue

195 alphanodavirus flock house virus (FHV) is a positive-strand RNA virus with one of the smallest known

196 TRV is a bipartite, positive-strand RNA virus with the TRV1 and TRV2 genomes

197 dicted RNA secondary formation in genomes of positive-stranded RNA viruses with their in vivo fitness

198 Hepatitis C virus (HCV) is a positive-strand RNA virus within the Flaviviridae family

199 Positive-strand RNA viruses within the Picornaviridae fa

200 of important human infections are caused by positive-strand RNA viruses, yet almost none can be trea