ライフサイエンスコーパス: postcapillary

1 d-type mice (n=6), we found less bacteria in postcapillary (60+/-6 versus 32+/-5 bacteria) and collec

2 nteract with adherent leukocytes in inflamed postcapillary and collecting venules.

3 ecommended to differentiate between isolated postcapillary and combined pre-/postcapillary pulmonary

4 ations was caused by widespread adhesion and postcapillary blockage.

5 alciparum-infected erythrocytes (Pf-IRBC) in postcapillary brain endothelium is a hallmark of cerebra

6 diately improved after TAVI in patients with postcapillary combined (57.8+/-14.1 versus 50.4+/-17.3 m

7 ed to epinephrine with increased adhesion to postcapillary endothelium in nude mice.

8 od cells (RBCs) and leukocytes as they enter postcapillary expansions, but the details of the fluid d

9 We further simulate postcapillary flow of SS-RBC suspensions with different

10 de lymphocytes (LNCs) tethered and rolled in postcapillary high endothelial venules (HEVs) and to a l

11 left ventricular end-diastolic pressure into postcapillary (left ventricular end-diastolic pressure,

12 at parasitized erythrocytes can sequester in postcapillary microvessels of critical tissues such as t

13 of 433 (75%) patients and was predominantly postcapillary (n=269/325; 82%).

14 cohort of 255 patients with PH from pre and postcapillary pathogeneses was assembled from 2 centers.

15 Postcapillary PH is associated with a decreased survival

16 Postcapillary PH is generally associated with a diastoli

17 Finally, patients with postcapillary PH were divided into isolated (n=220) and

18 Postcapillary PH with elevated vascular gradients and pu

19 ombination of mean PAP and mean PAWP defines postcapillary PH.

20 his combination of criteria defines isolated postcapillary PH.

21 tality to physiological measures of pre- and postcapillary PH.

22 n, and shorter life expectancy than isolated postcapillary PH.

23 een isolated postcapillary and combined pre-/postcapillary pulmonary hypertension (Cpc-PH) in left he

24 pulmonary arterial pressures versus isolated postcapillary pulmonary hypertension (P<0.05).

25 arterial hypertension, and in patients with postcapillary pulmonary hypertension because of left hea

26 The remainder have postcapillary pulmonary hypertension secondary to left v

27 es a subset of PH-LHD patients from isolated postcapillary pulmonary hypertension to Cpc-PH, which is

28 ich may classify Cpc-PH patients as isolated postcapillary pulmonary hypertension.

29 nt of left ventricular failure in those with postcapillary pulmonary hypertension; and hydroxyurea or

30 ACh was to induce a reduction in the pre- to postcapillary resistance ratio.

31 el flow past multiple adherent leukocytes in postcapillary size vessels.

32 increased leukocyte rolling and adhesion in postcapillary skin venules that were both inhibited afte

33 e circulation and reduced deposition in deep postcapillary vascular beds.

34 terations in sRBC/endothelium adhesion under postcapillary venular conditions.

35 was widespread basal plasma extravasation in postcapillary venular endothelia in NEP-/- mice, which w

36 V-CD8eNOSGFP (ECV-304 transfected cells) and postcapillary venular endothelial cells (CVEC).

37 926 (derived from human umbilical vein), and postcapillary venular endothelial cells (derived from bo

38 Duffy Ag expressed on RBCs, capillaries, and postcapillary venular endothelial cells binds selective

39 translocation and permeability properties of postcapillary venular endothelial cells.

40 Under postcapillary venular shear stress (1 dyne/cm2), sickle

41 Our results show that capillary-postcapillary venule diameter ratio, RBC configuration,

42 d cells as they flow from a capillary into a postcapillary venule using a lattice Boltzmann approach.

43 We constructed composite models of the human postcapillary venule, combining ECs with PCs or PC-depos

44 In flow chamber experiments, under postcapillary venule-like flow conditions, the pretreatm

45 Most of the leakage occurred in postcapillary venules (< 40-microns diameter), whereas m

46 of 478 microbubbles (13.6%) observed in six postcapillary venules 11 to 30 microm in diameter and 24

47 s and vascular permeability were measured in postcapillary venules after 4-hour and 1-hour reperfusio

48 TDLN cells began migrating across pulmonary postcapillary venules and first appeared within metastas

49 e blood were investigated in mouse cremaster postcapillary venules and in flow chambers coated with P

50 of neutrophils along the endothelial wall of postcapillary venules and integrin-mediated arrest.

51 ity begins in the superficial arterioles and postcapillary venules and progresses to the capillary be

52 ross HEVs is faster than across conventional postcapillary venules and requires a unique set of adhes

53 borders between endothelial cells that line postcapillary venules at that site.

54 ting leukocytes were labeled and observed in postcapillary venules for adhesion before and up to 120

55 l cells from human renal arteries as well as postcapillary venules from lymphoid tissue.

56 theless, the number of leukocytes rolling on postcapillary venules in an E-selectin-dependent manner

57 bone marrow (BM) endothelium and to inflamed postcapillary venules in an E-selectin-dependent manner.

58 phocyte-associated Ag tether on the walls of postcapillary venules in inflamed skin via interaction w

59 othelial venules (HEV) are specialized plump postcapillary venules in lymphoid tissues that support h

60 es can be found marginalized in the lumen of postcapillary venules in postmortem brain tissue derived

61 nd sialyl Lewis(x) (sLe(x)) to interact with postcapillary venules in the absence of PSGL-1.

62 ) increases clearance of macromolecules from postcapillary venules in the in situ oral mucosa and, if

63 duced neutrophil rolling and adhesion to the postcapillary venules in the mouse ears is significantly

64 , E-selectin, and ICAM-1 are up-regulated on postcapillary venules in the retina.

65 eukocyte trafficking across mouse mesenteric postcapillary venules in vivo.

66 s required to sustain neutrophil adhesion in postcapillary venules in vivo.

67 arkedly reduced (>60%) leukocyte adhesion to postcapillary venules in wild type and Fpr1(-/-), but no

68 Transendothelial migration of neutrophils in postcapillary venules is a key event in the inflammatory

69 d that the abundance of leukocyte rolling in postcapillary venules is due to interactions between red

70 Plasma extravasation from postcapillary venules is one of the earliest steps of in

71 ncreased expression of P-selectin protein in postcapillary venules of all vital organs after trauma.

72 s the leukocyte-endothelial cell adhesion in postcapillary venules of HCD mice.

73 Leukocyte rolling in postcapillary venules of inflamed tissues is reduced in

74 ng and adhesion were measured in cremasteric postcapillary venules of septic and control rats using i

75 med soluble ICs are rapidly deposited in the postcapillary venules of the cremaster microcirculation,

76 nt microbeads flowing within mildly inflamed postcapillary venules of the cremaster muscle in vivo.

77 in vivo, studied by intravital microscopy in postcapillary venules of the cremaster muscle, was marke

78 was restricted to focal areas of the retinal postcapillary venules of the inner vascular plexus.

79 s leukocyte-endothelial cell interactions in postcapillary venules of the mouse cremaster muscle.

80 yte-endothelial cell adhesion in cremasteric postcapillary venules of wild-type (WT) mice, CuZn-super

81 sed to monitor L/E and P/E adhesion in brain postcapillary venules of wild-type (WT), SOD1 transgenic

82 mber of adherent and emigrated leukocytes in postcapillary venules of WT HCD mice was significantly h

83 n is important in inflammation and occurs in postcapillary venules over a wide range of wall shear st

84 se model suggest that adherent leukocytes in postcapillary venules play a critical role in vaso-occlu

85 E-selectin and P-selectin on dermal postcapillary venules play critical roles in the migrati

86 that P-selectin and E-selectin expressed on postcapillary venules play overlapping roles in the recr

87 d leukocyte-endothelial cell interactions in postcapillary venules revealed that CXCL1-induced neutro

88 thelium may regulate neutrophil migration in postcapillary venules through the presentation of variou

89 ltered adhesive interactions within inflamed postcapillary venules under conditions of blood flow by

90 reveal that the basement membrane of dermal postcapillary venules undergoes changes in structure and

91 Wall shear stress in postcapillary venules varies widely within and between t

92 Intravital video microscopy of cremasteric postcapillary venules was performed.

93 Postcapillary venules were dilated, and up to 70% of the

94 Tracheal postcapillary venules were visualized and leukocyte kine

95 hodamine-stained leukocytes were observed in postcapillary venules with analysis for adhesion and rol

96 ed a network of arterioles, capillaries, and postcapillary venules with continuous blood flow.

97 ntibody fluorescence intensity in submucosal postcapillary venules with the use of intravital microsc

98 Intravital microscopy of postcapillary venules within the cremaster muscle of mic

99 ial permeability and leakage of albumin from postcapillary venules within the dura mater.

100 increased in the superficial arterioles and postcapillary venules, 2 weeks after the onset of diabet

101 sed luminally by endothelial cells that line postcapillary venules, a primary site of leukocyte recru

102 ed adhesion of leukocytes in capillaries and postcapillary venules, but no such adhesion in arteriole

103 about midway between terminal arterioles and postcapillary venules, challenging the classical concept

104 adhesion of leukocytes to discrete sites on postcapillary venules, followed by upregulation of adhes

105 mbranes that arise from inflamed venules and postcapillary venules, increase in size as the disease p

106 f leukocyte-endothelial cell interactions in postcapillary venules, leading to leukocyte recruitment

107 Neutrophil extravasation occurs across postcapillary venules, structures composed of endothelia

108 including endothelial cells of capillary and postcapillary venules, the epithelial cell of kidney col

109 designed to approximate physiologic flow in postcapillary venules, we have characterized a rolling i

110 In postcapillary venules, where shear stress is approximate

111 ill offer an effective, direct access to the postcapillary venules, where the target event (leukocyte

112 ma that tumor vessels arise exclusively from postcapillary venules.

113 erial/venous characteristics and derive from postcapillary venules.

114 re weeks exhibit an inflammatory response in postcapillary venules.

115 occur primarily via capillaries rather than postcapillary venules.

116 nomethyl-L-arginine (NMA) on skeletal muscle postcapillary venules.

117 rolling eosinophils, but not neutrophils, to postcapillary venules.

118 y designed to mimic physiologic flow through postcapillary venules.

119 ophages and erythrocytes) in capillaries and postcapillary venules.

120 leukocyte rolling and adhesion in mesenteric postcapillary venules.

121 rteries and veins, most arterioles, and some postcapillary venules.

122 utrophil emigration across murine mesenteric postcapillary venules.

123 ophil but not eosinophil rolling in inflamed postcapillary venules.

124 nd pericytes (PCs) that form the wall of the postcapillary venules.

125 deficient in in vivo crawling and TEM in the postcapillary venules.

126 o the relatively low-oxygen and low-velocity postcapillary venules.

127 and E-selectin-dependent adhesion in airway postcapillary venules.

128 ualize rolling of endogenous Tregs in dermal postcapillary venules.

129 pial vessels and in deep ascending cortical postcapillary venules.

130 y channels connecting terminal arterioles to postcapillary venules.

131 displayed on endothelial cells in intestinal postcapillary venules.

132 shear stress levels similar to that found in postcapillary venules.

133 tructure and increases leukocyte adhesion in postcapillary venules.

134 sults in vasculitic lesions predominantly in postcapillary venules.

135 enous malformations, and focal dilatation of postcapillary venules.

136 gap formation, and protein extravasation in postcapillary venules.

137 small lymphocytes for the endothelium of the postcapillary venules.

138 rolling effector and central memory cells in postcapillary venules.

139 e and continue to roll as elongated cells in postcapillary venules.

140 es as the main L-selectin ligand in inflamed postcapillary venules.

141 minants of the initiation of cell rolling in postcapillary venules.

142 eukocyte rolling and adherence in mesenteric postcapillary venules.

143 in tissues that possess receptors for SP in postcapillary venules; (ii) liposome material in these t