ライフサイエンスコーパス: postinoculation

1 r and spleen colonization levels up to 120 h postinoculation).

2 d pigs as early as 8 months of age (6 months postinoculation).

3 rain stem response thresholds at 3 or 7 days postinoculation.

4 associated with S. aureus 30 min and/or 6 h postinoculation.

5 s in the airway and the alveoli at 2 and 4 h postinoculation.

6 f 31 serial plasma samples as early as day 1 postinoculation.

7 that began on day 6 and was lethal by day 9 postinoculation.

8 d pneumonia were observed histologically 6 h postinoculation.

9 f 51 serial plasma samples as early as day 1 postinoculation.

10 lated from the fourth recipient about 1 year postinoculation.

11 mediated clearance during the first few days postinoculation.

12 d 100% of mice, even when delayed until 96 h postinoculation.

13 . meliloti at the early time point of 3 days postinoculation.

14 expressed in infected rosette leaves at 12 d postinoculation.

15 -infected groups and euthanized at 18 months postinoculation.

16 ed pigtailed macaques on days 4, 14, and 114 postinoculation.

17 ion of bacterial colonization 1, 4, and 48 h postinoculation.

18 ) exhibited chronic colitis through 7 months postinoculation.

19 hite blood cells and in lung tissue at day 2 postinoculation.

20 ecomes associated with the lesions by 5 days postinoculation.

21 gh level until they were euthanized 8 months postinoculation.

22 inimal to mild inflammation at days 7 and 28 postinoculation.

23 RNA (vRNA) were detected in blood by 2 weeks postinoculation.

24 nd the number of 6BPS plasma cells increased postinoculation.

25 VCC, and MAb-8 staining was optimal on day 2 postinoculation.

26 d draining lymph nodes between 3 and 10 days postinoculation.

27 number of Vsa variants were seen by 21 days postinoculation.

28 ent mice but only after a minimum of 21 days postinoculation.

29 sis thaliana, causing plant mortality 7 days postinoculation.

30 al numbers of the deltapagP mutant on day 14 postinoculation.

31 positive-control pigs at 9, 10, and 11 days postinoculation.

32 d are capable of causing plant mortality 7 d postinoculation.

33 s positive and seroconverted by 3 to 5 weeks postinoculation.

34 adders, or kidneys of mice harvested at 48 h postinoculation.

35 VcpzBF1167 (Env H280Q and Q380R) at 14 weeks postinoculation.

36 he lower respiratory tract for up to 49 days postinoculation.

37 cyte responses were observed at 2 to 4 weeks postinoculation.

38 hology in mice examined at both 2 and 4 days postinoculation.

39 iglets were challenged with PC21A at 3 weeks postinoculation.

40 this defect was apparent within 1 to 2 days postinoculation.

41 caques that progressed to AIDS 9 to 16 weeks postinoculation.

42 fter bacterial colonization starting 15 days postinoculation.

43 5), or mild (n = 2) encephalitis at 3 months postinoculation.

44 d with HPS (r = -0.95, P = 0.01) at 530 days postinoculation.

45 a reference live attenuated SIV at 12-14 mo postinoculation.

46 examined at 109, 150, 245, 368, and 530 days postinoculation.

47 nimals but were upregulated at 7 and 14 days postinoculation.

48 ung histopathology was normal up to 368 days postinoculation.

49 M antibodies (titer, 1:5 to 1:1,280) 14 days postinoculation.

50 Ureaplasma was undetectable 28 days postinoculation.

51 died with opportunistic infections 5.9 years postinoculation.

52 6) CFU/ml of blood between day 14 and day 36 postinoculation.

53 inoculation and macrophages at 2 and 14 days postinoculation.

54 ar tissue on day 14, and in joints on day 28 postinoculation.

55 , and samples were collected at 6 to 7 weeks postinoculation.

56 M. pneumoniae and sacrificed at 0 to 42 days postinoculation.

57 g in fewer than 200 cells/microl by 96 weeks postinoculation.

58 nt lethal challenge with WT virus at 21 days postinoculation.

59 mation in some mice that resolves by 28 days postinoculation.

60 of the infection from 60 hours to 110 hours postinoculation.

61 ins in different organs and at various times postinoculation.

62 ed in diarrhea that lasted from 1 to 10 days postinoculation.

63 onary inflammation, which cleared by 28 days postinoculation.

64 the middle ear were monitored up to 1 month postinoculation.

65 low the limit of detection at 30 and 60 days postinoculation.

66 with wild-type B. bronchiseptica at 10 days postinoculation.

67 uce a positive test response through 10 days postinoculation.

68 those of the transparent variant for 10 days postinoculation.

69 a halo around their colonies at 8 to 10 days postinoculation.

70 esponse around their colonies at 2 to 3 days postinoculation.

71 l organisms within microglial cells by day 7 postinoculation.

72 ol dsSIN-infected mosquitoes at 5 and 9 days postinoculation.

73 ed these transcripts at 10 min, 3 h, and 6 h postinoculation.

74 mice were indistinguishable from 1 to 3 days postinoculation.

75 tance 1 mRNA) were determined up to 72 hours postinoculation.

76 e to the virus-only inoculation group at 3 h postinoculation.

77 ory tracts of mice and was complete by day 6 postinoculation.

78 allbladder epithelial cells as early as 12 h postinoculation.

79 le to eliminate S. aureus even after 28 days postinoculation.

80 ice and showed that clearance begins 14 days postinoculation.

81 static conditions were completely lysed 24 h postinoculation.

82 both CD4(+) and CD8(+) T cells within 1 week postinoculation.

83 nts undergoing treatment as early as 5 weeks postinoculation.

84 served by week 4 and on the palate by week 6 postinoculation.

85 zation of the denture and palate for 8 weeks postinoculation.

86 ufficient to persist during the first 3 days postinoculation.

87 nd liver tissues of infected mice at 19 days postinoculation.

88 ays postinoculation and for at least 21 days postinoculation.

89 V, and tumors were not detectable at 21 days postinoculation.

90 initiated synthesis of EMICE within 4 to 6 h postinoculation.

91 chs (9-fold-lower bacterial load) at 9 weeks postinoculation.

92 tics of a chronic state within fourteen days postinoculation.

93 Colonization was assessed 12 weeks postinoculation.

94 lected at time points ranging from 3 to 14 h postinoculation.

95 and the pgdA mutant was observed at 3 weeks postinoculation (1.32 x 10(4) versus 1.85 x 10(3) CFU/gr

96 Animals were necropsied at 2 weeks postinoculation; 100% of F344, 42% of SD, 10% of LEW, an

97 By 2 h postinoculation, 70.0% (+/- 5.5%) of intracellular bacte

98 During the preleukemic period (4 to 10 weeks postinoculation) a marked decrease in thymic size is app

99 At 1 day postinoculation, a seronegative calf (contact animal) wa

100 urs, and were at baseline levels by 24 hours postinoculation, a time when high levels of circulating

101 At over 1.5 years postinoculation, all four juvenile macaques remain healt

102 d G1N4 were cleared from the brain by 7 days postinoculation and all animals survived without apparen

103 wer than that of the parental strain by 12 h postinoculation and decreased further by 24 h.

104 her viremia and tissue titers at 24 and 48 h postinoculation and faster neuroinvasion than mice given

105 st challenge with WT FMDV as early as 2 days postinoculation and for at least 21 days postinoculation

106 all became seropositive around 2 to 3 weeks postinoculation and had a decline in CD4/CD8 T-cell rati

107 rved between plasma viremia at 2 and 8 weeks postinoculation and in vitro susceptibility (P < 0.05).

108 vels in intestinal tissue between 2 and 24 h postinoculation and increased OPN protein in intestinal

109 honuclear leukocytes 1 to 2 days and 14 days postinoculation and macrophages at 2 and 14 days postino

110 using on the innate immune response at day 2 postinoculation and on gene expression in affected lung

111 sured by plethysmography, was detected 1 day postinoculation and persisted even after pulmonary infla

112 nal antibodies reacting to MgpB were induced postinoculation and persisted throughout the infection.

113 duced number of transformed cells at 5 weeks postinoculation and the presence of fewer gross tumors.

114 r bacteria present in a tight vacuole at 2 h postinoculation and the presence of numerous bacteria in

115 cylic acid signaling, was very low until 8 d postinoculation and then rose sharply, coinciding with t

116 ation to deep tissues for as long as 3 weeks postinoculation and to be critical for B. burgdorferi in

117 ak DC recruitment was detected at 10-15 days postinoculation and was significantly greater (p < 0.05)

118 macaques during acute SIV infection (10 days postinoculation) and during terminal infection when ther

119 of non-parasite-specific IgA (days 38 to 63 postinoculation) and IgM (days 24, 35, 38, and 52 postin

120 plantable tumor-forming cells at 3 to 4 week postinoculation, and (iii) the efficient generation of r

121 ower in the partially recovered cells at 5 h postinoculation, and lower still in the preadapted cells

122 Variants were detected by day 7 postinoculation, and multiple variants were present conc

123 mock-infected animals at days 1, 3, 5, and 7 postinoculation, and samples were analyzed for different

124 aried the time of initiation and duration of postinoculation antiretroviral treatment with tenofovir

125 rmined time points (1 h and 3, 5, and 7 days postinoculation), blood and bronchoalveolar lavage (BAL)

126 atory tracts of BALB/c mice beginning 1 week postinoculation but did not differ from the wt strain in

127 -DNA (bDNA) assay, reached a peak at 2 weeks postinoculation but dropped to below detectable levels b

128 s in the spinal cord and brain at late times postinoculation but lower titers in the liver in compari

129 onization, the mutant is outcompeted at 12 h postinoculation but then competes evenly by 24 h.

130 iters of autologous NAb developed by 4 weeks postinoculation but were not associated with control of

131 evels of viremia in the acute phase (2 weeks postinoculation) but are showing a relatively low viral

132 th SHIVs were potently suppressed by week 12 postinoculation, but a burst of viremia at week 51 was a

133 ding of prions in saliva increases with time postinoculation, but is common throughout the preclinica

134 ere severely defective during the first week postinoculation compared to their wild-type parent.

135 s in approximately 60% mortality within 48 h postinoculation, concomitant with amplified local inflam

136 ract infection was observed at up to 77 days postinoculation (d.p.i.).

137 In serum, IL-6 was significantly elevated at postinoculation day (PID) 1 in the VirHRV group and at P

138 kg of body weight/day, intramuscularly) from postinoculation day (PID) 1 to 6.

139 h virulent Wa (P1A[8],G1) human rotavirus at postinoculation day (PID) 21 (two-dose VLP regimen) or 2

140 CV-4408 and then challenged with BCoV DB2 at postinoculation day (PID) 21.

141 At postinoculation day (PID) 28, pigs either were euthanize

142 No viremia was detected through postinoculation day 10.

143 Both eyes of each mouse were enucleated on postinoculation day 15 and processed for histopathologic

144 re Mac-1-positive cells were detected early (postinoculation day 2) in the injected eyes of mice infe

145 by ELISPOT assay at the day of challenge, at postinoculation day 28 (WaV, WaA, and Mock) or at postch

146 yme-linked immunosorbent assay in the acute (postinoculation day 3 [PID 3]) and convalescent (PID 28)

147 nzyme-linked immunosorbent assay at selected postinoculation days (0 to 28).

148 Virus shedding began at postinoculation days (PID) 1 to 3 and continued up to PI

149 Pigs from postinoculation days (PID) 1 to 4 tested positive for Hu

150 Imaging was performed on postinoculation days 0, 1, 3, and 6 to document sites an

151 On postinoculation days 3, 7, and 10, injected eyes of non-

152 Culture supernatants, collected at various postinoculation days, were used for the analyses of chem

153 At 12 h, 3 days, 7 days, and 14 days postinoculation, DbpA/B-deficient spirochetes were signi

154 opsy specimens obtained at 3, 6, and 9 weeks postinoculation demonstrated no significant difference i

155 Nasal washes performed 7, 14, and 21 days postinoculation demonstrated that strain DBB25 colonized

156 On days 1 to 3 postinoculation, disease signs caused by oseltamivir-res

157 ubpatent levels within approximately 2 weeks postinoculation, double-KO mice developed high levels of

158 s, peak levels of viremia occurred at 5 days postinoculation (DPI) and were most consistently detecta

159 mRNA sequencing (mRNA-seq) at 3 and 12 days postinoculation (dpi) in 4 animals for each time point.

160 , 7, 10, 13, 16, 20, 24, 28, 35, and 42 days postinoculation (dpi), and the remaining chickens were n

161 eight loss and mortality beginning by 9 days postinoculation (dpi).

162 e necropsied at 3, 7, 14, 20, 27, or 55 days postinoculation (DPI).

163 from the three inoculated groups at 35 days postinoculation (DPI).

164 necropsied at 3, 7, 14, 20, 27, and 55 days postinoculation (DPI).

165 ebo was injected intraperitoneally at 2 days postinoculation (DPI; low dose) or 4 DPI (medium and hig

166 ed 2 animals from each group prior to (1 day postinoculation [dpi]) and at 1 (2 dpi) and 6 days postc

167 nt times after intrarectal inoculation (days postinoculation [dpi]) with simian immunodeficiency viru

168 reased in very early infection (8 to 10 days postinoculation [dpi]).

169 ases of the infection but was lost by day 14 postinoculation, during clearance of the infection; (iv)

170 ection in the bladder and kidneys by 6 hours postinoculation, fliC mutant bacteria were able to colon

171 Within 2 h postinoculation, fluorescently labeled C. neoformans had

172 ral therapy, initiated at a time point (48 h postinoculation) following simian immunodeficiency virus

173 r as a powder (each given preinoculation and postinoculation for a total of 4 studies) and placebo we

174 reovirus 1/L, and evaluated at various days postinoculation for in situ apoptosis by TUNEL analysis

175 nt challenges and at 6, 16, 48, 60, and 72 h postinoculation for the cochallenges.

176 FU/g bladder or kidney was determined 3 days postinoculation for the independent challenges and at 6,

177 ens collected sequentially on different days postinoculation from chickens experimentally infected wi

178 Mycoplasmas were cultured 3, 14, and 21 days postinoculation from the nose, lung, trachea, liver, and

179 ed and 3 down-regulated genes in the month-1 postinoculation group and 31 up-regulated and 2 down-reg

180 ed and 2 down-regulated genes in the month-3 postinoculation group.

181 At 6 months postinoculation,H. pylori had successfully colonized wit

182 ncephalitis in 100% of animals within 7 days postinoculation; however, viruses G3N4 and G1N4 were cle

183 BLM imaging detected WEEV and VEEV at 12 h postinoculation (hpi) at the injection site (footpad) an

184 MA104 cells, with maximum titer reached 24 h postinoculation (hpi).

185 inary tract infection at 4, 24, 48, and 72 h postinoculation (hpi).

186 cytes independent of DENV replication by 4 h postinoculation (hpi).

187 nfection in the bladder (P = 0.0295) at 48 h postinoculation (hpi).

188 ive neutrophils and macrophages and, at 72 h postinoculation, IL-17-positive CD4(+) T cells, suggesti

189 By 8 wk postinoculation, immunocompetent mice resolved both card

190 ns to resist clearance during the first week postinoculation in a manner dependent on B- and T-cell-m

191 g lung bacterial clearance when administered postinoculation in animals with established infection an

192 e activities were present from weeks 4 to 12 postinoculation in both animals.

193 er tissues, decreased dramatically by 5 days postinoculation in both wild-type and Rag1(-/-) mice, su

194 rons were quantified from days 9 through 240 postinoculation in latently infected trigeminal ganglia

195 erplasia overlying infected dermis four days postinoculation in wild-type mice.

196 At 96 h postinoculation, in addition to memory CD4(+) T cells, H

197 genes were differentially expressed at 1 day postinoculation, including an increase in the expression

198 By week 6 and week 8 postinoculation, increasing percentages of rats exhibite

199 roscopic observations of hydathodes six days postinoculation indicated a digestion of the epithem cel

200 At longer postinoculation intervals, infected neurons were found i

201 By 21 days postinoculation, levels of tetramer-binding cells had dr

202 s most severe in the nonadapted cells at 3 h postinoculation, lower in the partially recovered cells

203 At approximately 50 weeks postinoculation, mice were euthanized for histopathologi

204 At specific times postinoculation, mice were sacrificed, and lungs were re

205 were allowed to incubate for up to 73 months postinoculation (mpi).

206 (HAI) scores (P < 0.0001) at 6 and 11 months postinoculation (MPI).

207 At 4 h postinoculation, mutant LCVs had a significantly reduced

208 Herein we show that by 7 days postinoculation, nearly 30% of the CD4 T cells in the ac

209 A declined to undetectable levels by 14 days postinoculation of TriGAS, we speculate that a transient

210 At 48 h postinoculation, only one strain, Bp340::pDbpaC, demonst

211 sham-inoculated controls at both 4 and 24 h postinoculation (P < 0.05 in all cases).

212 ifferent at both 10 (P < 0.0001) and 28 days postinoculation (p.i.) (P = 0.002).

213 be detected in protoplasts as early as 12 h postinoculation (p.i.) and accumulated to high levels by

214 at eight time points from day 21 to day 217 postinoculation (p.i.) and examined their tissues for vi

215 us shedding in nasal washes for up to 5 days postinoculation (p.i.) and in lung tissue of inoculated

216 like lesions for 4/4 lungs at days 14 and 28 postinoculation (p.i.) and positive PCR detection of M.

217 collected on days -2, 1, 3, 5, 7, 14, and 21 postinoculation (p.i.) and tested by one of three commer

218 trols, and the inflammation resolved by 72 h postinoculation (p.i.) in both groups.

219 e effects of p53(+/-), infection status, and postinoculation (p.i.) time on inflammation, preneoplast

220 s earlier, and the percent survival on day 6 postinoculation (p.i.) was five times lower than for mic

221 odeficiency virus from SMs (SIVsm) by day 30 postinoculation (p.i.) with lepromatous tissue.

222 At 3 weeks postinoculation (p.i.), <25% of the ticks contained dete

223 Animals were euthanized at 2 or 4 h postinoculation (p.i.), and tissues were collected to as

224 ed at comparable levels at 4, 7, and 10 days postinoculation (p.i.), as determined by virus isolation

225 ium was shown to replicate from 0 to 80 days postinoculation (p.i.), during which at most time points

226 d increasing levels of serum RNA from week 1 postinoculation (p.i.), reaching a peak of 10(6) copies/

227 Further, at 7 days postinoculation (p.i.), spliced SIV RNA levels were the

228 a collected from mice infected 8 to 120 days postinoculation (p.i.), we found that a subset of saliva

229 0(7) to 10(9) SIVrcm RNA copies/ml by day 10 postinoculation (p.i.).

230 proximately monthly thereafter until day 251 postinoculation (p.i.).

231 marrow, and spleen as early as 1 to 2 weeks postinoculation (p.i.).

232 d immunohistochemistry between days 1 and 12 postinoculation (p.i.).

233 nd viremia, with clearance under way by 96 h postinoculation (p.i.).

234 that T cells were first detectable at 4 days postinoculation (p.i.).

235 peaked at weeks 17 (Ch1535) and 12 (Ch1536) postinoculation (p.i.).

236 me infected and died at between 2 and 4 days postinoculation (p.i.).

237 Based on the postinoculation percent weight change per h and serum bi

238 monocytes of infected dogs during the 56-day postinoculation period.

239 Starting on postinoculation (PI) day 28, tear swabs were collected o

240 r lymph nodes, and inoculated eyes peaked at postinoculation (pi) day 5 and declined by pi day 7.

241 V) encephalitis with neuronal dysfunction by postinoculation (pi) day 84.

242 ma peaked at 2 weeks and declined by 4 weeks postinoculation (PI).

243 tive control), were killed at 6 and 18 hours postinoculation (PI).

244 of SIVmnd-1 viral replication (days 7 to 10 postinoculation), plasma VLs were high (8 x 10(6) to 8 x

245 o reduce survival despite reducing the 3 day-postinoculation pulmonary pathogen burden by 400-fold.

246 Even at 30 days postinoculation, RB63-infected animals had lower serum a

247 tion frequencies occurring at 30 and 120 min postinoculation, respectively.

248 CR in 70 and 22% of mice at 109 and 530 days postinoculation, respectively.

249 Analysis of isolates from 14 days postinoculation revealed less variation of the Vsa prote

250 Histological examination at 18 weeks postinoculation revealed minimal gastric inflammation in

251 Eight days postinoculation, rVSV was eliminated from the olfactory

252 Twelve weeks postinoculation, SIV-infected macaques had significantly

253 sculoskeletal tissues that peak from 10-14 d postinoculation, suggesting that CD8(+) T cells contribu

254 e, but not joint-associated tissues, at 14 d postinoculation, suggesting that the ability of CD8(+) T

255 Within 7 days postinoculation, TC-PC177 caused mild diarrhea and lower

256 ibodies against SHIV-89.6 at 10 and 20 weeks postinoculation than Indian rhesus macaques.

257 noculation) and IgM (days 24, 35, 38, and 52 postinoculation) than C57BL/6J nude mice in feces (P < 0

258 At 2 weeks postinoculation, the bacterial cells were mostly trapped

259 By 48 hours postinoculation, the fliC mutant bacteria were attenuate

260 However, by 21 days postinoculation, the level of pneumonia in the dual-infe

261 However, at 21 weeks postinoculation, the livers from mice inoculated with wi

262 By week 4 postinoculation, the majority of inoculated rats with de

263 fection in the ganglion; (ii) at early times postinoculation, the number of neurons expressing viral

264 By 6 h postinoculation, the release of proinflammatory cytokine

265 Ten weeks postinoculation, the severity of typhlocolitis was asses

266 tion of viral reporter proteins at different postinoculation times allowed us to determine the sequen

267 However, by day 12 postinoculation, titers in all organs examined were 10-

268 s and were necropsied at several time points postinoculation to assess inflammation, dysplasia, and n

269 from all P28 OMPs were detected from day 30 postinoculation to day 468 and from day 46 until day 159

270 In contrast, as early as 2 h postinoculation, transcriptional up-regulation of GST1-a

271 inoculated monkey developed AIDS at week 137 postinoculation, transfer of its infected blood to a nai

272 ous rechallenge achieved following transient postinoculation treatment compared favorably to the resu

273 Postinoculation treatment did not block the initial infe

274 Even postinoculation treatment regimens that did not prevent

275 ontrolled plasma viremia following transient postinoculation treatment showed substantial resistance

276 n regulating S. pneumoniae biofilms, at 24 h postinoculation, two different D39DeltaluxS mutants prod

277 At 40 and 42 months postinoculation, two i.c.-inoculated cats developed sign

278 ) percentages averaged nearly 70% within 7 d postinoculation using the TRBO-sgRNA constructs, which r

279 d prevention of chronic infection at 2 weeks postinoculation using two different P. aeruginosa strain

280 , KGF given every 3 days beginning on day 15 postinoculation was associated with reversal of weight l

281 ia recovered from the rat trachea at 10 days postinoculation was significantly decreased compared to

282 prion disease to assess various time points postinoculation, we identified 15 unreported genes that

283 L/DeltaUK were protected as early as 14 days postinoculation when challenged with ASFV-G.

284 ia in vivo would be inhibited at early times postinoculation, when the numbers of inflammatory cells

285 r deer became PrP(CWD) positive by 19 months postinoculation, whereas none of the four deer inoculate

286 e PrP(CWD) positive in as little as 6 months postinoculation, whereas none of the four deer receiving

287 IAI) results in 100% mortality by 48 to 72 h postinoculation, while monomicrobial infections are avir

288 spirochete numbers at 2, 4, 8, and 12 weeks postinoculation with 10(5) B. burgdorferi B31 clone 5A4

289 m or INP0341 treated intravaginally pre- and postinoculation with 5 x 10(2) inclusion-forming units (

290 strain colonized the birds as early as day 2 postinoculation with a density as high as 10(7) CFU/g of

291 in mouse hearts from 1 week to over 5 months postinoculation with CVB3/TD demonstrated that CVB3/TD v

292 d-type Arabidopsis leaves beginning 4 to 7 h postinoculation with P. syringae carrying either avrRpt2

293 e transcriptome at 0, 4, 8, 12, 24, and 48 h postinoculation with PM.

294 cid levels increased in V. vinifera at 120 h postinoculation with PM.

295 At 50 d postinoculation with Rocky Mountain Laboratory (RML) pri

296 e in extracellular proteins was observed 6 h postinoculation with S. aureus, with the increase domina

297 We assayed these sites 3 h postinoculation with transcript arrays for the Toll-like

298 ues were inoculated with SIVmac239 and, 4 wk postinoculation (WPI) treated with intramuscular injecti

299 itive for anti-avian HEV antibody at 4 weeks postinoculation (wpi).

300 ed severe neurological dysfunction 196-231 d postinoculation (x =198; 95% CI: 210-216) and tested pos