ライフサイエンスコーパス: postsynaptic cell

1 t not by the same inhibitors loaded into the postsynaptic cell.

2 he information that can be communicated to a postsynaptic cell.

3 ion of their receptor fields within a shared postsynaptic cell.

4 e-sensitive K+-Cl- transport activity in the postsynaptic cell.

5 time courses of Ca(2+) introduction into the postsynaptic cell.

6 ynaptic inputs with action potentials in the postsynaptic cell.

7 he number of motor axons that innervate each postsynaptic cell.

8 ted animals form synapses with more than one postsynaptic cell.

9 synaptic cleft, eliciting a response in the postsynaptic cell.

10 between PKA activation in the presynaptic or postsynaptic cell.

11 potentials or constant depolarization in the postsynaptic cell.

12 ein synthesis in the presynaptic but not the postsynaptic cell.

13 en if the transgene is expressed only in the postsynaptic cell.

14 of synapses that results from injury to the postsynaptic cell.

15 nergic input may trigger axonogenesis in the postsynaptic cell.

16 als from interneuron axons that surround the postsynaptic cell.

17 mental and functional states of the pre- and postsynaptic cell.

18 ation via regulation of Wnt signaling in the postsynaptic cell.

19 fined by the identity of the presynaptic and postsynaptic cell.

20 tes to the collection of signals sent to the postsynaptic cell.

21 s insensitive to chelation of calcium in the postsynaptic cell.

22 ct quenching of this phosphoinositide at the postsynaptic cell.

23 ll body, the central nervous system, and the postsynaptic cell.

24 reams even where they converge onto the same postsynaptic cell.

25 istinct sources of perisomatic inhibition to postsynaptic cells.

26 on regulatory interactions between pre- and postsynaptic cells.

27 ted to impose a transient temporal filter on postsynaptic cells.

28 of GABA release following depolarization of postsynaptic cells.

29 formation and stabilization with individual postsynaptic cells.

30 e resting potentials of both presynaptic and postsynaptic cells.

31 Held terminal and compare them with those of postsynaptic cells.

32 by bidirectional signaling between pre- and postsynaptic cells.

33 otentials by hyperpolarizing the membrane of postsynaptic cells.

34 es reciprocal communication between pre- and postsynaptic cells.

35 alignment and attachment of presynaptic and postsynaptic cells.

36 voked IPSCs (eIPSCs) by activating mAChRs on postsynaptic cells.

37 selection between individual presynaptic and postsynaptic cells.

38 s regulated by interactions between pre- and postsynaptic cells.

39 multiple synapses with the same or different postsynaptic cells.

40 ound in both presynaptic nerve terminals and postsynaptic cells.

41 lar synaptomatrix separating presynaptic and postsynaptic cells.

42 ubcellular structures occur in both pre- and postsynaptic cells.

43 may be detected by either neuronal or glial postsynaptic cells.

44 determined from random samples of unlabelled postsynaptic cells.

45 ts while completely disconnecting from other postsynaptic cells.

46 rmation exchange between the presynaptic and postsynaptic cells.

47 of different kinds of inputs onto individual postsynaptic cells.

48 and physiological properties of the pre- and postsynaptic cells.

49 al effects on the excitability of respective postsynaptic cells.

50 ng phase locking between the presynaptic and postsynaptic cells.

51 in leading to transcriptional alterations in postsynaptic cells.

52 unoreactivity (IR) and AP frequency in these postsynaptic cells.

53 ter upon a discrete combination of different postsynaptic cells.

54 ecreted BDNF can act on both presynaptic and postsynaptic cells.

55 eptors are expressed on both presynaptic and postsynaptic cells.

56 requires proper interaction between pre- and postsynaptic cells.

57 resynaptic cell types converge onto a common postsynaptic cell, acting together to shape neuronal out

58 CIH induces an increase in NTS postsynaptic cell activity initiated by spontaneous pres

59 e results indicate that signals initiated by postsynaptic cell adhesion molecule ApCAM coupled with t

60 ere we show that conditional deletion of the postsynaptic cell adhesion molecule neuroligin-3 in parv

61 ts of synapses by binding extracellularly to postsynaptic cell adhesion molecules and intracellularly

62 Neuroligins are postsynaptic cell adhesion molecules that are important

63 h repeat transmembrane proteins (LRRTMs) are postsynaptic cell adhesion molecules that bind to presyn

64 Neuroligins (NLGNs) are postsynaptic cell adhesion molecules that interact trans

65 Neuroligins are evolutionarily conserved postsynaptic cell adhesion molecules that interact with

66 The reduced shedding of essential postsynaptic cell adhesion proteins such as N-Cadherin,

67 ockout (cKO) mice of neuroligin-2 (Nlgn2), a postsynaptic cell-adhesion molecule of inhibitory synaps

68 However, many other postsynaptic cell-adhesion molecules are known and the r

69 Neuroligins (NLs) are postsynaptic cell-adhesion molecules essential for norma

70 Neuroligins are postsynaptic cell-adhesion molecules genetically linked

71 Neuroligins are postsynaptic cell-adhesion molecules implicated in autis

72 ynaptic cell-adhesion molecules that bind to postsynaptic cell-adhesion molecules such as neuroligins

73 Neuroligins (NLs) are postsynaptic cell-adhesion molecules that are implicated

74 Neuroligins are postsynaptic cell-adhesion molecules that bind presynapt

75 Neuroligins are postsynaptic cell-adhesion molecules that bind to presyn

76 Neuroligins are postsynaptic cell-adhesion molecules that bind to presyn

77 Neuroligins are postsynaptic cell-adhesion molecules that contribute to

78 Neuroligins are evolutionarily conserved postsynaptic cell-adhesion molecules that function, at l

79 Neuroligins are postsynaptic cell-adhesion molecules that interact with

80 Thus, our data suggest that two unrelated postsynaptic cell-adhesion molecules, LRRTMs and neuroli

81 ons in genes encoding neuroligins, which are postsynaptic cell-adhesion molecules.

82 be mediated by interactions between pre- and postsynaptic cell-adhesion molecules.

83 The postsynaptic cells also displayed bimodal inward current

84 nnabinoids (eCBs), which are produced in the postsynaptic cell and act on the presynaptic terminal, a

85 r current, decreasing covariance between the postsynaptic cell and afferents activated by the second

86 ane-N,N,N', N'-tetraacetate (BAPTA) into the postsynaptic cell and is similar to long-term potentiati

87 ncreasing covariance between activity of the postsynaptic cell and its afferents that were activated

88 ter accounting for only 70% of the effect on postsynaptic cell and protons released together with the

89 membrane FasII levels in the presynaptic and postsynaptic cell and requires the presence of the fly h

90 calcium-dependent regulatory protein in the postsynaptic cell and suggests that hemichannels on the

91 arity of the responses in different types of postsynaptic cell and the properties of miniature EPSCs

92 polarization, on the influx of Ca2+ into the postsynaptic cell and, at least in part, on the activati

93 ll-cell contact between appropriate pre- and postsynaptic cells and is followed by recruitment of pro

94 fusible lipophilic molecules are released by postsynaptic cells and regulate presynaptic neurotransmi

95 Thus, synaptic learning rules vary with the postsynaptic cell, and may require the interaction of di

96 of Agrn mutant mice, demonstrating that the postsynaptic cell, and MuSK in particular, has a potent

97 eptors is homosynaptically controlled by the postsynaptic cell, and that it is not due to constitutiv

98 These results indicate that the activity of postsynaptic cells, and the activation of NMDA receptors

99 rocess require interactions between pre- and postsynaptic cells, and which proceed cell-autonomously.

100 ogether, endogenous PSD-95 and SAP102 in the postsynaptic cell appear to regulate transcellularly the

101 ar junction, receptors expressed in a single postsynaptic cell are confronted with an array of hundre

102 e, the integration time and threshold of the postsynaptic cell are matched to the statistics of conve

103 natal gerbil LSO, but their receptors on the postsynaptic cells are.

104 on of LTP required correlated spiking of the postsynaptic cell as well as the activation of the NMDA

105 then discuss their alignment across pre- and postsynaptic cells at a nanometer scale.

106 eceptors (R cells), targeting four different postsynaptic cells at each synapse (tetrad).

107 er in presynaptic or in both presynaptic and postsynaptic cells at early developmental or postdevelop

108 dings are one of the first demonstrations of postsynaptic, cell-autonomous actions of endocannabinoid

109 For GABAergic but not glutamatergic postsynaptic cells, BDNF induced a shift in the reversal

110 t the adhesive mechanisms that link pre- and postsynaptic cells before synapse formation may be diffe

111 ampal cultures, deletion of TrkB in only the postsynaptic cell, before synapse formation, also result

112 idual axons according to the identity of the postsynaptic cell being innervated.

113 s, with cortical and inhibitory input to the postsynaptic cell blocked.

114 c-like somatic spines, which extend from the postsynaptic cell body, form an exception.

115 l large neurofilament bundles encircling the postsynaptic cell body.

116 xistence of Y1- and Y2-like receptors in the postsynaptic cell body.

117 m stereotypic connections with an individual postsynaptic cell, but how a single presynaptic cell typ

118 acterized for its function in activating the postsynaptic cell, but the significance of spontaneous r

119 a noncanonical Wnt signaling pathway in the postsynaptic cell by modulating the internalization of t

120 als a large membrane structure engulfing the postsynaptic cell by the end of embryogenesis.

121 ing to both presynaptic (class-specific) and postsynaptic (cell-by-cell) factors.

122 e contact a common interneuron partner, each postsynaptic cell can arrive at a different connectivity

123 la glutamatergic neuromuscular junction, the postsynaptic cell can regulate synaptic strength by both

124 Postsynaptic cells can induce synaptic plasticity throug

125 Neurotransmitter receptors on postsynaptic cells change to match the identity of the n

126 between neurons, whereas presynaptic versus postsynaptic cell classes dictate the connectivity, effi

127 sence of tetrodotoxin, depolarization of the postsynaptic cell consistently produced a broadening of

128 ctions use glutamate as transmitter, and the postsynaptic cells contain both NMDA and AMPA receptors.

129 This indicates that postsynaptic cells coordinate the plasticity of their in

130 o the nucleus of the presynaptic but not the postsynaptic cell during 5-HT-induced long-term facilita

131 Here we report that a surrogate postsynaptic cell expressing full-length NLG-1 triggers

132 zed "detonator" synapses that potently drive postsynaptic cell firing through their profound frequenc

133 across dendritic compartments, and (2) that postsynaptic cell-firing is the critical trigger for ind

134 we hypothesized that receptor expression in postsynaptic cells follows changes in transmitter expres

135 eus (PrV), trigeminal afferent terminals and postsynaptic cells form discrete modules ("barrelettes")

136 Postsynaptic cells generate positive and negative signal

137 synaptic release probability, effects on the postsynaptic cell have not been reported.

138 ich afferent input regulates the survival of postsynaptic cells have received considerably less atten

139 ented, but the cytomorphological dynamics of postsynaptic cells have received less attention.

140 Permanent removal of axonal input to postsynaptic cells helps shape the pattern of neuronal c

141 s and a retrograde signal synthesized by the postsynaptic cell in an activity-dependent manner.

142 an unexpected nerve-independent role for the postsynaptic cell in generating this topological complex

143 cal antagonists to either the presynaptic or postsynaptic cell in paired whole-cell recordings from h

144 To better understand the role of the postsynaptic cell in the differentiation of presynaptic

145 y juxtacellular current, applied to a single postsynaptic cell in the primary ACx.

146 through the release of endocannabinoids from postsynaptic cells in a manner that could not be blocked

147 ar to those that occur following ablation of postsynaptic cells in adult animals.

148 In contrast, recordings from postsynaptic cells in brainstem slices, and acutely diss

149 he dynamic cell surface remodeling needed by postsynaptic cells in coordinating synaptogenesis initia

150 tions of several molecules on the surface of postsynaptic cells in order to choose a particular targe

151 r potentials but a defective response of the postsynaptic cells in the optic lamina.

152 ffectively normalizing the combined input to postsynaptic cells in the tectum.

153 e, but the relative roles of presynaptic and postsynaptic cells in these changes are only beginning t

154 mination in vivo and asked whether the major postsynaptic cells in this circuit, the ganglion cells,

155 we inhibited protein synthesis in individual postsynaptic cells in vivo while monitoring presynaptic

156 The stimulus for axon growth is not postsynaptic cell inactivity because axons grow into uno

157 ents leading to substrate/Na+ release to the postsynaptic cell, including the structure and dynamics

158 uronal input can lead to profound changes in postsynaptic cells, including atrophy and cell death.

159 elator BAPTA (10 mm) was introduced into the postsynaptic cell, indicating that the tonic inhibition

160 ntral synapses, endocannabinoids released by postsynaptic cells inhibit neurotransmitter release by a

161 system, the number of axonal inputs to each postsynaptic cell is dramatically reduced.

162 The model accounts for LTP and LTD when the postsynaptic cell is voltage clamped and depolarized (LT

163 s to the overall synaptic activity of single postsynaptic cells is essential to our understanding of

164 aptic depression and facilitation, or at the postsynaptic cell level because of subthreshold membrane

165 ssibility that membrane fusion events in the postsynaptic cell may be required for the change in syna

166 d NO donors, suggested that NO released from postsynaptic cells mediated FSI and likely activated pre

167 synaptic neuron with a depolarization of the postsynaptic cell mimicked the decrease of unitary IPSCs

168 s, excitatory inputs may alter the firing of postsynaptic cells more effectively than inhibitory inpu

169 e activity of presynaptic cells according to postsynaptic cell outputs and to maintain synaptic funct

170 Moreover, infusing a PKA inhibitor into postsynaptic cells produced synaptic depression that occ

171 Communication between pre- and postsynaptic cells promotes the initial organization of

172 synaptic junctions on individual, identified postsynaptic cells reflected the overall postsynaptic ta

173 signaling is an important mechanism by which postsynaptic cells regulate the structure and function o

174 the reciprocal interactions between pre- and postsynaptic cells required for the development of matur

175 ise recordings from the CiA interneurons and postsynaptic cells reveal that the Engrailed-1 neurons p

176 P was prevented by with voltage clamping the postsynaptic cell soma during high-frequency stimulation

177 t of a synapse-specific Hebbian factor and a postsynaptic-cell-specific homeostatic factor, with each

178 nd those that shared a common presynaptic or postsynaptic cell, suggesting local perisynaptic influen

179 olished after dialyzing 40 mm BAPTA into the postsynaptic cell, suggesting that DHPG activated postsy

180 These results suggest that postsynaptic cells supply two types of signals to motor

181 molecular epitope spreading between GluR3, a postsynaptic cell surface protein, and munc-18, a presyn

182 y recruiting AMPA glutamate receptors to the postsynaptic cell surface.

183 nce of cell bodies from both presynaptic and postsynaptic cells, synaptic efficacy increased for 48 h

184 naptic interneuron but is unrelated to their postsynaptic cell target.

185 Introducing substances into the postsynaptic cell that block membrane fusion at a number

186 functional neurotransmitter receptors on the postsynaptic cell that is regulated by interaction with

187 ry machinery is a retrograde signal from the postsynaptic cell that mediates the formation of synapti

188 sed to mediate interactions between pre- and postsynaptic cells that are necessary for synapse format

189 investigated GABAA receptor localization in postsynaptic cells that fail to receive presynaptic cont

190 At single postsynaptic cells that receive innervation from multipl

191 homeostatic potentiation of inhibition onto postsynaptic cells that show increased levels of excitat

192 h different cells (e.g. myelinating glia and postsynaptic cells), the recruitment and retention of AI

193 Synaptotagmin 4 (Syt4) is transmitted to the postsynaptic cell through anterograde delivery of Syt4 v

194 r clusters but acts transcellularly from the postsynaptic cell through N-cadherin to enhance asynchro

195 By comparing biophysical maturation of the postsynaptic cell to alterations in presynaptic organiza

196 spike frequencies are more likely to cause a postsynaptic cell to fire than are bursts with higher or

197 Regulating the response of a postsynaptic cell to neurotransmitter is an important me

198 0-Hz stimulation or by depolarization of the postsynaptic cell to prevent block of NMDA-specific glut

199 w a novel form of plasticity that allows the postsynaptic cell to selectively modulate spontaneous ne

200 hich it is released, and the response of the postsynaptic cell to that transmitter all contribute to

201 nections requires a dialogue between pre and postsynaptic cells to coordinate the assembly of the pre

202 ation requires interactions between pre- and postsynaptic cells to establish the connection of a pres

203 uced by synaptic activities are derived from postsynaptic cells to potentiate presynaptic properties,

204 s retrograde messengers that are released by postsynaptic cells to regulate neurotransmitter release

205 can act as retrograde messengers that allow postsynaptic cells to regulate the strength of their syn

206 ons and interactions between presynaptic and postsynaptic cells together promote the segregation of c

207 ment, neuromuscular junctions and some other postsynaptic cells transition from multiple- to single-i

208 ibition was also found to be brain state and postsynaptic cell type dependent but that alone could no

209 We conclude that postsynaptic cell type determines presynaptic terminal m

210 precise spike timing, synaptic strength, and postsynaptic cell type in the activity-induced modificat

211 ing the identity of both the presynaptic and postsynaptic cell type is key when analyzing neocortical

212 y fiber inputs to CA3 GABAergic cells on the postsynaptic cell type was correlated with the frequency

213 unique, a function of presynaptic cell type, postsynaptic cell type, environment, developmental stage

214 en shown at some synapses to depend upon the postsynaptic cell type.

215 ors, but the receptor density depends on the postsynaptic cell type.

216 form distinct wiring patterns with multiple postsynaptic cell types during development remains unexp

217 ranule cells are purely glutamatergic in all postsynaptic cell types tested.

218 the division of common inputs among multiple postsynaptic cell types to create parallel circuits with

219 individual presynaptic cells contact several postsynaptic cell types, generating divergence of signal

220 is unclear how the graded potentials control postsynaptic cells under physiological conditions.

221 orchestrated communication between pre- and postsynaptic cells via coordinated trans-synaptic signal

222 l role in conferring presynaptic patterns to postsynaptic cells via neurotransmitter receptor-mediate

223 e simply a transient influx of Ca2+ into the postsynaptic cell, via either NMDA receptors or voltage-

224 regulated by neurotrophins secreted from the postsynaptic cell was examined in Xenopus nerve-muscle c

225 ed Ca2+ chelators nitr-5 or nitrophen in the postsynaptic cell was sufficient to induce persistent sy

226 ly be assigned to particular presynaptic and postsynaptic cells without specialized labeling methods.