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1 es at extrasynaptic sites (>0.5 mum from the postsynaptic density).
2 ctivity-dependent accumulation of tau in the postsynaptic density.
3 alpha is present in a mobile fraction of the postsynaptic density.
4 are a family of scaffolding proteins of the postsynaptic density.
5 major scaffolding protein of the excitatory postsynaptic density.
6 nclude modulation of receptor trafficking to postsynaptic density.
7 Rs) is regulated by scaffold proteins in the postsynaptic density.
8 nents of the presynaptic active zone and the postsynaptic density.
9 removal of AMPA receptors (AMPARs) from the postsynaptic density.
10 single presynaptic active zone and a single postsynaptic density.
11 stering of glutamate receptors (GLUR) at the postsynaptic density.
12 for coupling AMPAR endocytic zones with the postsynaptic density.
13 tructural protein found predominantly at the postsynaptic density.
14 re less rigidly organized than glutamatergic postsynaptic densities.
15 plasma membranes, close to, but not within, postsynaptic densities.
16 xchange factor that is localized in neuronal postsynaptic densities.
17 concentration of synaptic vesicles near the postsynaptic densities.
18 ntaining small, round vesicles and prominent postsynaptic densities.
19 regulation of mGluR1 in 5-HT(2A)R-containing postsynaptic densities.
20 d in the brain and is highly enriched within postsynaptic densities.
21 otentially compensatory expansion of AZs and postsynaptic densities.
22 ma membrane and in dendritic spines close to postsynaptic densities.
23 at received E treatment, ER-alpha within the postsynaptic density (30-60 nm from the synaptic membran
26 synaptic cell adhesion molecule) and PSD-93 (postsynaptic density-93) are scaffold proteins that bind
27 egatively regulated dendritic spine density, postsynaptic density 95 (PSD-95) clustering, and surface
31 ation, and protein/protein interactions (eg, postsynaptic density 95 (PSD95)), may drive the predispo
32 ls concomitant with higher levels of 5-HT2CR:postsynaptic density 95 complex distinguished HI rats fr
33 amate transporter 1 and 2) and postsynaptic (postsynaptic density 95) markers, as well as dopaminergi
35 teracts with proteins through its three PDZ (postsynaptic density 95, discs large, zonula occludens-1
36 utamate transporter 1-positive (VGlut1+) and postsynaptic density 95-positive (PSD95+) puncta, on PV
38 tory factor-1 (NHERF1) is a cytoplasmic PDZ (postsynaptic density 95/disc large/zona occludens) prote
39 gion specifically interacted with the NHERF1 postsynaptic density 95/disc-large/zona occludens-1 doma
40 w that the expression of GRIP1, a multi-PDZ (postsynaptic density 95/discs large/zona occludens) doma
41 nteraction modules in mammalian cells is the postsynaptic density 95/discs large/zonula occludens 1 (
45 ulatory protein (E3KARP) both consist of two postsynaptic density 95/disks large/zona occludens-1 (PD
46 d presynaptic (Synapsin-1) and postsynaptic (postsynaptic density 95; PSD-95) staining, diffuse demye
47 an age-related increase in the ratio of both postsynaptic density-95 (PSD-95) and the GluN2A subunit
49 se hippocampal organotypic slice cultures, a postsynaptic density-95 (PSD-95) knock-out mouse line an
50 te (NMDA) neurotransmitter receptors and the postsynaptic density-95 (PSD-95) membrane-associated gua
51 entries into spines regulate the increase in postsynaptic density-95 (PSD-95) protein after brain-der
53 ies on intracellular calcium signaling, PDZ [postsynaptic density-95 (PSD-95)/Discs large (Dlg)/zona
56 ressed increase in other proteins, including postsynaptic density-95 and alpha-calcium/calmodulin-dep
58 Translational induction of an FMRP target, postsynaptic density-95 mRNA, required both PP2A and UPS
59 sults in increased spine density and PSD-95 (postsynaptic density-95) accumulation in membrane region
60 is provided by the scaffold protein PSD-95 (postsynaptic density-95), which is associated with alpha
61 peptide (KV1-C peptide) corresponding to the postsynaptic density-95, discs large, zonula occludens-1
63 The EAAT2b cytoplasmic C terminus contains a postsynaptic density-95/Discs large/zona occludens-1 (PD
65 interaction between SAP102 and NR2B is PDZ (postsynaptic density-95/Discs large/zona occludens-1) do
66 rotein kinase and myosin domains, and a PDZ (postsynaptic density-95/Discs Large/zona occludens-1) sc
67 P-REX2 provides high-affinity binding to the postsynaptic density-95/Discs large/zona occludens-1-bin
69 boxyl terminal (CT) of Cx43, incorporating a postsynaptic density-95/disks-large/ZO-1 (PDZ)-binding d
70 that are symmetric (in that there is little postsynaptic density), a characteristic of inhibitory sy
71 labeled endings in the DCN formed asymmetric postsynaptic densities, a feature of excitatory neurotra
72 ical slices and blocks Pyk2 translocation to postsynaptic densities, a key step required for Pyk2 act
74 the major scaffolding protein at excitatory postsynaptic densities and a potent regulator of synapti
75 ve more stubby spine structures with smaller postsynaptic densities and an increase in the frequency
76 hippocampus, gamma-8 and CNIH-2 associate in postsynaptic densities and CNIH-2 protein levels are mar
77 nt tau depleted PSD-95, resulting in smaller postsynaptic densities and impaired synaptic localizatio
78 e, BC1 KO mice have enlarged spine heads and postsynaptic densities and increased synaptic levels of
79 abundance of the GluN2B subunit of NMDAR in postsynaptic densities and NMDAR-dependent long-term pot
81 allows for the concomitant remodeling of the postsynaptic density and actin spinoskeleton and for the
82 n is accompanied by PTEN localization at the postsynaptic density and anchoring within the spine.
83 iary subunits, SynDIG4 is de-enriched at the postsynaptic density and colocalizes with extrasynaptic
84 flow-cytometry analysis, down-regulation of postsynaptic density and dendrite spine morphology regul
85 kinases (MAGUKs) are major components of the postsynaptic density and play important roles in synapti
86 actin is presumed to anchor receptors in the postsynaptic density and play numerous roles regulating
87 geted mass spectrometry was used to quantify postsynaptic density and voltage-gated calcium channel p
90 , synaptic vesicles, spines, spine apparati, postsynaptic densities, and mitochondria) are rendered a
91 ptic terminals, labelling both dendrites and postsynaptic densities, and simultaneously labelling a r
92 dly, SynCAM 1 can form ensembles proximal to postsynaptic densities, and synapses containing these en
93 illed cells, ultrastructural analysis of the postsynaptic density, and electrophysiological recording
94 ed, including the subsynaptic reticulum, the postsynaptic density, and the glutamate receptor cluster
95 ors receptors and signaling molecules to the postsynaptic density-and are regulated by the phosphoryl
98 number of release sites, active zone length, postsynaptic density area and number of vesicles in the
99 resynaptic AZ number per bouton area and the postsynaptic density area are both increased in dnlg2 mu
100 d spines had larger synapses, as measured by postsynaptic density area, than single-labeled and unlab
101 ynapses in M1 were larger than in S1 (median postsynaptic density areas of 0.064 mum(2) vs 0.042 mum(
102 res of neurons, such as dendritic spines and postsynaptic density areas, in addition to its distribut
103 marked, NMDA receptor-dependent increase in postsynaptic densities associated with activated (phosph
104 vity alone, robustly increased the number of postsynaptic densities associated with activated (phosph
105 lices to 1 nM E2 increases the percentage of postsynaptic densities associated with high levels of im
106 97, and SAP102 are central organizers of the postsynaptic density at excitatory synapses on pyramidal
107 one of the main scaffolding proteins of the postsynaptic density at GABAergic synapses, to monitor t
108 de novo mutations in genes belonging to the postsynaptic density at glutamatergic synapses, particul
110 s are adjacent synaptic regions that share a postsynaptic density, but nascent zones lack the presyna
111 ), a K63-specific deubiquitinase enriched in postsynaptic densities, cleaves K63-chains from PSD-95.
114 old proteins, suggesting that maintenance of postsynaptic density composition is TNFalpha dependent.
115 ribution of GluN2B-immunolabeling within the postsynaptic density did not change after BZ withdrawal.
116 including reduced mGlu5 association with the postsynaptic density, enhanced constitutive mGlu5 signal
117 id expansion of the synaptic active zone and postsynaptic density, enhanced dendritic spine plasticit
118 lcin, the clathrin adaptor molecule AP2, the postsynaptic density enriched protein PSD-95 and NMDARs.
119 calization of mGluR5 to both synaptosome and postsynaptic density-enriched fractions in the hippocamp
122 nt manner to facilitate its translocation to postsynaptic densities for synaptic tagging and maintena
123 subunits (GluA1/2/3/4) in homogenates and in postsynaptic density fractions from spinal cord dorsal h
124 is to identify changes in the composition of postsynaptic densities from GluN2B(-/-) mouse primary ne
127 e Extinction group, there was an increase in postsynaptic density GluR1, PSD95, and actin proteins; w
129 ding immunogold revealed AIDA-1 label within postsynaptic densities in both hippocampus and cortex.
132 tric disorders, has a regulatory role in the postsynaptic density in association with the NMDA-type g
133 esponses and GluA1 levels in the hippocampal postsynaptic density in wild-type and GluA1-S845A mutant
134 rgest CNVs (>500 kb) in genes present in the postsynaptic density, in genomic regions implicated via
135 T131-phosphorylated NDE1 is present at the postsynaptic density, in proximal axons, within the nucl
136 ssing PSD-95, a major scaffolding protein of postsynaptic density involved in synapse formation, syna
138 95, a principal scaffolding component of the postsynaptic density, is targeted to synapses by palmito
142 plasticity by orchestrating the assembly of postsynaptic density macromolecular signalling complex.
143 sity GluR1, PSD95, and actin proteins; while postsynaptic density mGluR5 protein decreased and there
144 proteins are major scaffold proteins of the postsynaptic density; mutations in the human SHANK3 gene
145 , Extinction training reversed the decreased postsynaptic density NMDAR1 protein in the Home and Box
147 e A (PKA), PKC, and calcineurin (CaN) to the postsynaptic densities of neurons, but its role in inhib
148 ty was not influenced by Nogo-A, the size of postsynaptic densities of PF-PC synapses was negatively
149 oltage-sensitive calcium ion channels at the postsynaptic density of a dendritic spine is investigate
151 intense synaptic activity drives tau to the postsynaptic density of excitatory synapses and that Abe
157 the content of the beta3 integrin subunit in postsynaptic density of the accumbens core at 24 h after
158 ations of PSD-95, Homer1b/c, and Narp in the postsynaptic density of the core, whereas no proteins me
159 eas no proteins measured were altered in the postsynaptic density of the shell in either extinguished
160 1-S845 and GluA1 levels in their hippocampal postsynaptic density on the third day of acquisition, wh
162 mmunocytochemistry, electron microscopy, and postsynaptic density preparation that LRP1 is located po
163 dentate hilus, and significant increases in postsynaptic density protein (PSD-95) were found along d
164 ifs with their interacting proteins, such as postsynaptic density protein (PSD95), Drosophila disc la
166 s were measured in the nucleus accumbens for postsynaptic density protein 95 (PSD-95) and SAP90/PSD-9
167 hat SR interacts with the synaptic proteins, postsynaptic density protein 95 (PSD-95) and stargazin,
168 ate (NMDA) receptor and its interaction with postsynaptic density protein 95 (PSD-95) at the synapse
169 mals and cultured slices, and an increase in postsynaptic density protein 95 (PSD-95) by overexpressi
171 72, whereas the synaptic scaffolding protein postsynaptic density protein 95 (PSD-95) stabilizes the
172 troporation of DsRedExpress- and eGFP-tagged postsynaptic density protein 95 (PSD-95) to investigate
174 egradation of the synaptic scaffold protein, postsynaptic density protein 95 (PSD-95), a process that
181 cal imaging of neurons expressing DsRed2 and postsynaptic density protein 95 fused to green fluoresce
183 on of GluN2A and GluN2B subunits, as well as postsynaptic density protein 95 in the rat hippocampus.
184 active, expanded allele (EX-Xa) have reduced postsynaptic density protein 95 protein expression, redu
185 found that the postsynaptic scaffold PSD-95 (postsynaptic density protein 95) undergoes K63 polyubiqu
187 ate a role for synaptic proteins synapsin-1, postsynaptic density protein 95, and glutamate receptor
188 s in spine density and levels of synapsin-1, postsynaptic density protein 95, and glutamate receptor
189 and levels of synaptic proteins synapsin-1, postsynaptic density protein 95, and glutamate receptor
190 av-1 and membrane/lipid raft localization of postsynaptic density protein 95, NMDA receptor, and trop
191 which targets the synaptic scaffold protein, postsynaptic density protein 95, to enhance downstream s
193 impairments in synapse-associated protein 90/postsynaptic density protein 95-associated protein 3 (SA
194 transporter 1-positive [VGlut1+] puncta and postsynaptic density protein 95-positive [PSD95+] puncta
195 Selective disruption of interactions with postsynaptic density protein 95/disks large/zonula occlu
196 ynapse-associated protein of 97 kilodaltons; postsynaptic density protein of 93 kilodaltons; synapse-
197 ct matches that of the prototypical scaffold postsynaptic density protein of 95 kDa (PSD-95) identify
199 membrane-associated guanylate-like kinases [postsynaptic density protein of 95 kilodaltons; synapse-
200 At this time, levels of GluN2A, GluN2B and postsynaptic density protein PSD-95 were all increased.
203 MRP) regulates expression of the scaffolding postsynaptic density protein PSD95, but the mode of cont
208 in postsynaptic structures can interact with postsynaptic density protein-95 (PSD-95), a key scaffold
209 complex of the synaptic scaffolding protein postsynaptic density protein-95 (PSD-95), neuronal nitri
210 re immunopositive for glutamate receptor and postsynaptic density proteins (viz., GluR1, GluR4, NR1,
211 of Ptchd1-interacting proteins that include postsynaptic density proteins and the retromer complex,
212 or subtypes are differentially stabilized by postsynaptic density proteins in or out of the postsynap
213 ine self-administration, and measurements of postsynaptic density proteins in the core and shell subc
214 he synapse and interacts with multiple known postsynaptic density proteins including the scaffolding
215 s on live neurons were labeled with sQDs and postsynaptic density proteins were visualized with super
217 naling cascades that converge onto GABAergic postsynaptic density proteins, we performed MS analysis
218 renia with the exception of a small group of postsynaptic density proteins, whose co-expression incre
220 or genes encoding members of mouse and human postsynaptic density proteomes (odds ratio 4.56, P = 5.0
221 major scaffolding protein in the excitatory postsynaptic density (PSD) and a potent regulator of syn
222 ucing IKK kinase complex is localized at the postsynaptic density (PSD) and activated under basal con
223 eatment, GluR1 subunits are increased at the postsynaptic density (PSD) and at extrasynaptic sites, w
224 conditioned inhibition groups, the ratio of postsynaptic density (PSD) area to docked vesicles at sy
225 term depression (LTD), and a thinning of the postsynaptic density (PSD) at hippocampal synapses.
226 n SGNs to drive differentiation of the large postsynaptic density (PSD) characteristic of the ribbon
228 ositioning of glutamate receptors within the postsynaptic density (PSD) determine excitatory synaptic
229 show that an exocytic domain adjacent to the postsynaptic density (PSD) enables fusion of large, AMPA
230 in (GAP) found in high concentrations in the postsynaptic density (PSD) fraction from the mammalian f
231 .2 L-type Ca(2+) channel mRNA and protein in postsynaptic density (PSD) fractions of the hippocampus,
233 ty of synapses, immunolabeled for either the postsynaptic density (PSD) marker PSD95 or the presynapt
234 SK2-containing channels are expressed in the postsynaptic density (PSD) of dendritic spines on mouse
235 organize an extensive protein complex at the postsynaptic density (PSD) of excitatory glutamatergic s
238 ses overall synapse proteome complexity, the postsynaptic density (PSD) proteome of zebrafish has low
240 ensin is an abundant scaffold protein in the postsynaptic density (PSD) that forms a high-affinity co
241 that PSD-95, a major scaffold protein of the postsynaptic density (PSD) that promotes synaptic streng
243 finement in the synapse, and trapping at the postsynaptic density (PSD) through reversible interactio
244 g, and receptor molecules concentrate at the postsynaptic density (PSD) to regulate synaptic strength
245 ribution patterns of the two isoforms at the postsynaptic density (PSD) under basal and excitatory co
247 K-801 binding and NMDA receptor complexes in postsynaptic density (PSD) were in fact increased in sch
248 nd GEFs have been shown to be present at the postsynaptic density (PSD) within excitatory glutamaterg
249 in transiently decreased GluA1 levels at the postsynaptic density (PSD), but did not affect extrasyna
250 sion by establishing the architecture of the postsynaptic density (PSD), but the small size of the sy
251 MAGUKs), which are essential proteins in the postsynaptic density (PSD), cluster and anchor glutamate
253 nucleotide exchange factor localized to the postsynaptic density (PSD), modulates dendritic spine mo
254 fic reduction of dendritic spine density and postsynaptic density (PSD)-95 and spinophilin-positive c
257 with yoked-saline controls, 42 proteins in a postsynaptic density (PSD)-enriched subfraction of the N
268 neck) and the "distal" half (containing the postsynaptic density [PSD]), whereas after delayed fixat
269 uter and inner stratifying dendrites express postsynaptic density (PSD95) immunoreactive puncta sugge
272 protein (GAP) that is a major constituent of postsynaptic densities (PSDs) from mammalian forebrain.
273 n kinase II (CaMKII) is a major component of postsynaptic densities (PSDs) involved in synaptic regul
274 ependent modifications in the composition of postsynaptic densities (PSDs) isolated from rat primary
275 rphology and distribution of proteins within postsynaptic densities (PSDs) isolated from rats before
276 l surface-expression of EphA7 essentially in postsynaptic densities (PSDs) of dendritic spines and sh
277 in and metalloproteinase that resides in the postsynaptic densities (PSDs) of excitatory synapses, ha
278 alysis of membranes associated with isolated postsynaptic densities (PSDs) suggests the PSD-associate
279 arger volume and harbor significantly larger postsynaptic densities (PSDs) than those contacted by vG
280 PSD95 and SAP97 conformation in vitro and in postsynaptic densities (PSDs) using FRET and EM, and exa
281 the plasma membrane and is found at neuronal postsynaptic densities (PSDs), but the role of MyoVa in
282 ndrites in each individual neuron, except at postsynaptic densities (PSDs), where it is typically hig
285 urrent study investigated the expression and postsynaptic density redistribution of glutamate recepto
286 igin-1 (NL1), which is located at excitatory postsynaptic densities, regulates activity-dependent syn
289 ton-associated scaffold protein (ARC) of the postsynaptic density, sets previously implicated by geno
292 us synapses in layers 2-3 of LPFC had larger postsynaptic density surface areas and a higher proporti
295 mination of the majority of spines; however, postsynaptic densities were preserved on dendritic shaft
296 length, spine diameter, and the area of the postsynaptic density were measured from the 3D reconstru
297 e II (CaMKII) forms a major component of the postsynaptic density where its functions in synaptic pla
298 nes and colocalized with constituents of the postsynaptic density, whereas SNAP-25 was restricted to
299 these genes: 1) they localized to the human postsynaptic density, which is crucial for neuronal func
300 mity to synaptic contacts (<0.5 mum from the postsynaptic density), while 27% were distributed along
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