ライフサイエンスコーパス: postsynaptic membrane

1 eceptor and anchor it at high density in the postsynaptic membrane.

2 ent of GluR1 to restricted subregions of the postsynaptic membrane.

3 tration of neurotransmitter receptors at the postsynaptic membrane.

4 lve the insertion of AMPA receptors into the postsynaptic membrane.

5 cally associated, but not yet fused with the postsynaptic membrane.

6 neurotransmitter receptors accumulate in the postsynaptic membrane.

7 ization of alpha-Spectrin and Ankyrin to the postsynaptic membrane.

8 (alpha(1B)-class) with AMPA receptors in the postsynaptic membrane.

9 pon D(2) dopamine receptors localized in the postsynaptic membrane.

10 the functions of the Ca(2+) channels in the postsynaptic membrane.

11 uncovers new functions of the exocyst at the postsynaptic membrane.

12 cialized trafficking events occurring at the postsynaptic membrane.

13 ion and maintenance of recycled AChRs at the postsynaptic membrane.

14 f the receptor tyrosine kinase, MuSK, in the postsynaptic membrane.

15 ptic function and plasticity directly at the postsynaptic membrane.

16 hinery that delivers AMPA receptors into the postsynaptic membrane.

17 tional nerve terminal opposite a specialized postsynaptic membrane.

18 a neurotransmitter-gated ion channel in the postsynaptic membrane.

19 late stages of receptor trafficking into the postsynaptic membrane.

20 in a central mesh immediately underlying the postsynaptic membrane.

21 density of approximately 900 microm-2 in the postsynaptic membrane.

22 are found in the perisynaptic region of the postsynaptic membrane.

23 stering of neurotransmitter receptors in the postsynaptic membrane.

24 een the nerve terminal and the receptor-rich postsynaptic membrane.

25 ainance of the molecular architecture of the postsynaptic membrane.

26 ialization dedicated to endocytosis near the postsynaptic membrane.

27 ole-4-propionic acid (AMPA) receptors to the postsynaptic membrane.

28 ustering of inhibitory neuroreceptors in the postsynaptic membrane.

29 ie directly opposite junctional folds in the postsynaptic membrane.

30 sma membrane, and later was recruited to the postsynaptic membrane.

31 zes a cytoskeletal- signaling complex at the postsynaptic membrane.

32 in neurones, where it is associated with the postsynaptic membrane.

33 them causes the topographic features of the postsynaptic membrane.

34 tinic acetylcholine receptors (nAChR) in the postsynaptic membrane.

35 ze that complex to a primary scaffold in the postsynaptic membrane.

36 r heteromeric NMDA receptors anchored at the postsynaptic membrane.

37 h NR2 and PSD-95 was highest just inside the postsynaptic membrane.

38 phaPS1, alphaPS2), expressed at least in the postsynaptic membrane.

39 BAergic synapses on distinct segments of the postsynaptic membrane.

40 the density and insertion of AChRs into the postsynaptic membrane.

41 ne receptors (nAChRs) at high density in the postsynaptic membrane.

42 idespread CNS expression and is found at the postsynaptic membrane.

43 miniature endplate currents produced at the postsynaptic membrane.

44 rily influenced by resistance changes in the postsynaptic membrane.

45 pendicular axis approximately 20 nm from the postsynaptic membrane.

46 n the differentiation and maintenance of the postsynaptic membrane.

47 nerve-dependent accumulation of AChRs in the postsynaptic membrane.

48 he terminal bouton, and a highly specialized postsynaptic membrane.

49 of a Grb2-mediated signaling cascade at the postsynaptic membrane.

50 receptors (AChRs) become concentrated in the postsynaptic membrane.

51 , between 30 nm outside and 40 nm inside the postsynaptic membrane.

52 ate myopathy and extensive remodeling of the postsynaptic membrane.

53 ersible influence on the organization of the postsynaptic membrane.

54 g the specific expression of utrophin at the postsynaptic membrane.

55 ce closely associated with both the pre- and postsynaptic membrane.

56 MAP1B in modulating access of AMPARs to the postsynaptic membrane.

57 (2+)-induced dissociation of PSD-95 from the postsynaptic membrane.

58 oximately 100 nm into the cytoplasm from the postsynaptic membrane.

59 r protein complexes assemble at the pre- and postsynaptic membrane.

60 es acetylcholine receptor insertion into the postsynaptic membrane.

61 g of internalized AMPA receptors back to the postsynaptic membrane.

62 nd their associated scaffold proteins in the postsynaptic membrane.

63 ng of acetylcholine receptors (AChRs) to the postsynaptic membrane.

64 is known of phosphoinositide function at the postsynaptic membrane.

65 mes play critical roles in maturation of the postsynaptic membrane.

66 4-propionic acid receptors (AMPARs) from the postsynaptic membrane.

67 a decrease of net charge-transfer across the postsynaptic membrane.

68 properties of glutamate receptors within the postsynaptic membrane.

69 y oriented filaments lying 10-20 nm from the postsynaptic membrane.

70 KA2 was concentrated to a greater degree on postsynaptic membranes.

71 ases do not act via traditional receptors on postsynaptic membranes.

72 (B)R1a/b and GABA(B)R2 was found in pre- and postsynaptic membranes.

73 otransmitter-gated Cl- channels localized in postsynaptic membranes.

74 mplex that regulates NMDARs stabilization at postsynaptic membranes.

75 ically copurifies with AChR solubilized from postsynaptic membranes.

76 junctional folds, another hallmark of mature postsynaptic membranes.

77 and stabilization is present at the pre- and postsynaptic membranes.

78 h AMPARs at densities comparable to those in postsynaptic membranes.

79 ressed in the brain on synaptic vesicles and postsynaptic membranes.

80 microscopy of ACh-sprayed and freeze-trapped postsynaptic membranes.

81 on of acetylcholine receptors (AChRs) in the postsynaptic membrane, a process that requires the AChR-

82 the presence of detachments between pre- and postsynaptic membranes, abnormally long active zones, an

83 of AMPA receptors (AMPARs) and lipids to the postsynaptic membrane, activities that are known to cont

84 line receptors (AChRs) recycle back into the postsynaptic membrane after internalization to interming

85 eptin inhibits these neurons directly at the postsynaptic membrane, alpha-MSH and NPY potently stimul

86 The postsynaptic membrane also undergoes restructuring durin

87 phorylation of a key CaMKII substrate in the postsynaptic membrane (AMPA receptor subunit glutamate r

88 ing to the formation of a highly specialized postsynaptic membrane and a highly differentiated nerve

89 these mutants, KCNQ4 fails to cluster at the postsynaptic membrane and appears diffused along the ent

90 ization of AChR-associated components of the postsynaptic membrane and cytoskeleton.

91 dies examined showed immunoreactivity in the postsynaptic membrane and densities, adjacent dendritic

92 al for both association of gephyrin with the postsynaptic membrane and gephyrin clustering.

93 In skeletal muscle, DAMAGE is at the postsynaptic membrane and is associated with a subset of

94 ic proteins are normally associated with the postsynaptic membrane and may contribute to the clusteri

95 This difference was significant at the postsynaptic membrane and postsynaptic density (i.e., sy

96 bility of AMPARs for trafficking between the postsynaptic membrane and the endosome.

97 show that DFrizzled2 is endocytosed from the postsynaptic membrane and transported to the nucleus.

98 e nicotinic acetylcholine receptor (AChR) in postsynaptic membranes and are useful for exploring the

99 noelectron microscopy localized synbindin on postsynaptic membranes and intracellular vesicles within

100 becomes progressively restricted to pre- and postsynaptic membranes and is undetectable by postnatal

101 Select adhesion molecules connect pre- and postsynaptic membranes and organize developing synapses.

102 i, agrin to cluster diffuse receptors in the postsynaptic membrane, and acetylcholine to evoke electr

103 the size of PSDs without changes in pre- or postsynaptic membrane, and depletes the number of membra

104 mism underlying macroscopic stability of the postsynaptic membrane, and establish alpha-dystrobrevin

105 results in changes in receptor number at the postsynaptic membrane, and hence modifications in synapt

106 and combination of receptor subunits in the postsynaptic membrane, and raise the possibility that ca

107 stsynaptic density proteins in or out of the postsynaptic membrane, and this differential synaptic ex

108 ((betaPS), expressed in both presynaptic and postsynaptic membranes, and two alpha subunits (alphaPS1

109 als, indicating that neither presynaptic nor postsynaptic membranes are major sites for glutamate rem

110 ility to recruit and retain receptors at the postsynaptic membrane as shown through deletion and knoc

111 in this process by adhering presynaptic and postsynaptic membranes as ingrowing thalamic axon termin

112 ic approaches to investigate the role of the postsynaptic membrane-associated lipase, diacylglycerol

113 magnocellular neurons via the activation of postsynaptic membrane-associated receptors and the relea

114 channel conductance and their density in the postsynaptic membrane at cerebellar Purkinje cell synaps

115 The postsynaptic membrane at each synaptic terminal is the f

116 a homolog of dystrophin, is confined to the postsynaptic membrane at skeletal neuromuscular junction

117 specialized and stably anchored beneath the postsynaptic membrane at the neuromuscular junction (NMJ

118 which induces the clustering of AChRs on the postsynaptic membrane at the neuromuscular junction.

119 e highest in the nuclei that lie beneath the postsynaptic membrane at the neuromuscular junction.

120 ediate neurotransmission by depolarizing the postsynaptic membrane at the neuromuscular junction.

121 osed of five subunits, is a component of the postsynaptic membrane at the vertebrate neuromuscular ju

122 function in the adhesion of presynaptic and postsynaptic membranes at excitatory synapses.

123 d from putative excitatory synapses, whereas postsynaptic membranes at GABAergic synapses often conta

124 in specific adhesion between presynaptic and postsynaptic membranes at glutamatergic synapses.

125 Delta receptors were found to be abundant on postsynaptic membranes at parallel fiber synapses from p

126 Erbin is concentrated in postsynaptic membranes at the neuromuscular junction and

127 The apposed presynaptic and postsynaptic membranes at this large area of synaptic co

128 ensity peaked approximately 40 nm inside the postsynaptic membrane, at the cytoplasmic fringe of the

129 nputs are removed, and the topography of the postsynaptic membrane becomes more complicated as gutter

130 At the postsynaptic membrane, beta1-integrins are found more co

131 st, Exo70 mediates receptor insertion at the postsynaptic membrane, but it does not participate in re

132 chemical signal into an ion flux through the postsynaptic membrane, but the molecular mechanism of ga

133 ly by the removal of AMPA receptors from the postsynaptic membrane, but the underlying molecular mech

134 rters limit transmitter concentration at the postsynaptic membrane by removing neurotransmitters from

135 ndant, neuronal transporters residing in the postsynaptic membrane can also shield receptors from the

136 and-gated ion-channel receptors associate in postsynaptic-membrane clusters by binding to the protein

137 ry for the clustering of AChRs and all other postsynaptic membrane components studied to date.

138 Changes in postsynaptic membrane composition underlie many forms of

139 Labeling within 25 nm of the postsynaptic membrane concentrated at the lateral edge o

140 The postsynaptic membrane contains a high concentration of g

141 access of AMPARs to dendritic spines and the postsynaptic membrane, contributing to downregulating sy

142 Thus, the density of AChRs in the postsynaptic membrane depends on immunoglobulin-containi

143 synaptic actions were not necessary to cause postsynaptic membrane depolarization and spiking.

144 number and type of receptors present at the postsynaptic membrane determine the response to the neur

145 The number of GABA(A) receptors in the postsynaptic membrane directly controls the efficacy of

146 Presynaptic and postsynaptic membranes directly oppose each other at che

147 stering of neurotransmitter receptors in the postsynaptic membrane, directly opposite the nerve termi

148 that directs the differentiation of pre- and postsynaptic membrane domains.

149 tant role in construction of the specialized postsynaptic membrane during synaptogenesis.

150 y removal of Mg(2+) or depolarization of the postsynaptic membrane during tetanus.

151 tein receptor), is required for expansion of postsynaptic membranes during new synapse formation.

152 on microscopy of tubular crystals of Torpedo postsynaptic membranes embedded in amorphous ice.

153 This finding indicates that elevated postsynaptic membrane excitability is by itself insuffic

154 omain, is here shown to govern the growth of postsynaptic membrane folds and the composition of gluta

155 Scaffolding molecules at the postsynaptic membrane form the foundation of excitatory

156 on of the acetylcholine receptor (AChR)-rich postsynaptic membrane from an ovoid plaque into a comple

157 h for novel dystroglycan binding partners in postsynaptic membranes from Torpedo electric organ.

158 At postsynaptic membranes, GluA2 physically binds N-cadheri

159 ionally, protein trafficking to and from the postsynaptic membrane has emerged as a key mechanism und

160 GABA(B)R1a and GABA(B)R1b, to presynaptic or postsynaptic membranes helps to determine this role.

161 ents at the presynaptic axon terminal versus postsynaptic membrane in an individual neuron.

162 nd Ca(2+)-induced release of PSD-95 from the postsynaptic membrane in dendritic spines.

163 pionic acid receptor moves in and out of the postsynaptic membrane in highly dynamic fashion.

164 alpha1 subunit showed that it was present at postsynaptic membranes in apposition to synaptic endings

165 cal role in L-LTP by holding nascent pre-and postsynaptic membranes in apposition, enabling incipient

166 munoreactive clusters; however, the pre- and postsynaptic membranes in between synaptic active zones

167 mmalian inhibitory glycinergic and GABAergic postsynaptic membranes in nerve cells.

168 PSD-95 is released from postsynaptic membranes in response to Ca(2+) influx via

169 first direct evidence that HR3 is present on postsynaptic membranes in the central nervous system.

170 abeling was observed at both presynaptic and postsynaptic membranes in the cortex and cerebellum.

171 tion specifically of the GluR1-AMPARs to the postsynaptic membranes in the LA, together with the rapi

172 s primary adhesive moieties between pre- and postsynaptic membranes in the synaptic complex.

173 n the gene ontologies 'cell projection' and 'postsynaptic membrane' in the gene lists derived from PD

174 AChRs from IFs was shown to lead to loss of postsynaptic membrane infoldings and disorganization of

175 he paired-pulse ratio without changes in the postsynaptic membrane input resistance or EPSC rise and

176 erived agrin triggers the differentiation of postsynaptic membrane into a highly specialized structur

177 sociation of AMPARs from their anchor on the postsynaptic membrane involves actin depolymerization, w

178 neurotransmitter receptor aggregation on the postsynaptic membrane is a critical event during synapse

179 The regulation of AMPA receptors at the postsynaptic membrane is a fundamental component of syna

180 dependent aggregation of dystroglycan in the postsynaptic membrane is a key step in synaptic maturati

181 ng of acetylcholine receptors (AChRs) in the postsynaptic membrane is a key step in synaptogenesis at

182 AMPA-type receptor (AMPAR) abundance in the postsynaptic membrane is an important mechanism involved

183 d suggests that the functional domain of the postsynaptic membrane is broader than previously recogni

184 lso plays a role in scaffolding GluR1 at the postsynaptic membrane is controversial, attributable to

185 Thus, Wnt-activated growth of the postsynaptic membrane is mediated by the synapse-to-nucl

186 ated in a use-dependent manner even when the postsynaptic membrane is not sufficiently depolarized to

187 The molecular composition of the postsynaptic membrane is sculpted by synaptic activity.

188 rganization of neurotransmitter receptors in postsynaptic membranes is a fundamental determinant of s

189 bundance of AMPA receptors in neurons and at postsynaptic membranes is tightly regulated.

190 associated with the cytoplasmic face of the postsynaptic membrane; its highest levels border regions

191 pses of the brain, specific receptors in the postsynaptic membrane lie ready to respond to the releas

192 Ras signaling at the postsynaptic membrane may be involved in the modulation

193 GABA(A) receptors located in the postsynaptic membrane mediate neuronal inhibition that o

194 mitoylation that facilitate the formation of postsynaptic membrane microdomains, which may serve key

195 glycine receptor (GlyR) clusters in discrete postsynaptic membrane microregions.

196 is a cytoskeletal specialization within the postsynaptic membrane of a neuron that helps to concentr

197 ly coupled to N-type calcium channels on the postsynaptic membrane of basal forebrain neurons.

198 receptor antibody at P10 was limited to the postsynaptic membrane of excitatory synapses and was abs

199 rafficking of AMPA receptors to and from the postsynaptic membrane of excitatory synapses are now bri

200 ein phosphatase-2B (PP2B/calcineurin) at the postsynaptic membrane of excitatory synapses where it is

201 nown to cluster at high concentration on the postsynaptic membrane of excitatory synapses, but the me

202 At the postsynaptic membrane of excitatory synapses, neurotrans

203 se clusters of alpha 1C are localized in the postsynaptic membrane of excitatory synapses, which are

204 Shank is enriched at the postsynaptic membrane of glutamatergic neuromuscular jun

205 At the postsynaptic membrane of glutamatergic synapses, the cAM

206 urons, SK channels are also expressed in the postsynaptic membrane of glutamatergic synapses, where t

207 ceptors are found highly concentrated in the postsynaptic membrane of glutamatergic synapses.

208 olic protein selectively concentrated at the postsynaptic membrane of inhibitory synapses, where it i

209 uces acetylcholine receptor synthesis in the postsynaptic membrane of neuromuscular synapses.

210 mate receptors are localized in the pre- and postsynaptic membrane of neurons in the brain.

211 required for its stable association with the postsynaptic membrane of NMJs.

212 n of additional AMPA-type receptors into the postsynaptic membrane of sensorimotor synapses via exocy

213 iny, amorphous structure located beneath the postsynaptic membrane of synapses in the CNS.

214 se muscle, Abl kinases were localized to the postsynaptic membrane of the developing NMJ.

215 uster acetylcholine receptors (AChRs) on the postsynaptic membrane of the neuromuscular junction (NMJ

216 eptors (AChRs) are present at the top of the postsynaptic membrane of the neuromuscular junction (NMJ

217 ylcholine receptors (AChRs) recycle into the postsynaptic membrane of the neuromuscular junction.

218 -immunoreactive varicosities that appose the postsynaptic membrane of these neurons.

219 In some cases M1R-ir was seen near the postsynaptic membrane of these processes, but in other c

220 lized on spine-like protrusions, adjacent to postsynaptic membranes of bushy cells in the cochlear nu

221 4 (GPC4) and LRRTM4 localize to the pre- and postsynaptic membranes of excitatory synapses, respectiv

222 de clustering acetylcholine receptors on the postsynaptic membranes of muscles and binding to the mus

223 4) inhibited endogenous ClC-3 conductance in postsynaptic membranes of neonatal hippocampal neurones.

224 acing to identify the receptors expressed on postsynaptic membranes of parallel fiber and auditory ne

225 1 and GIRK2 were found almost exclusively in postsynaptic membranes of putative excitatory synapses,

226 (AChRs) are clustered at high density in the postsynaptic membranes of skeletal neuromuscular junctio

227 luR2/3 and GluR2 antibodies) was high in the postsynaptic membranes of synapses at early postnatal ag

228 nicotinic acetylcholine receptors (AChR) on postsynaptic membranes of the neuromuscular junction.

229 localizes with the K(+) channel KCNQ4 at the postsynaptic membranes of these calyceal synapses.

230 and depends on their precise localization at postsynaptic membranes opposing the presynaptic neurotra

231 pionic acid (AMPA) receptors to and from the postsynaptic membrane plays an important role in regulat

232 of ionotropic glutamatergic signaling at the postsynaptic membrane, plays an unanticipated and essent

233 establish these effects are mediated by both postsynaptic membrane polarization and afferent axon fib

234 lts suggest that a dynamic regulation of the postsynaptic membrane potential by synaptic inhibition i

235 resynaptic glutamate release occurs when the postsynaptic membrane potential is relatively hyperpolar

236 zation (AHP), without affecting the pre- and postsynaptic membrane potential.

237 transmembrane channel, thereby altering the postsynaptic membrane potential.

238 nhibiting spike generation, depending on the postsynaptic membrane potential.

239 otentiation in both cell types is induced at postsynaptic membrane potentials below firing threshold,

240 umulation caused slow depolarizations of the postsynaptic membrane potentials, and thereby substantia

241 aptic vesicle content and the asymmetric pre/postsynaptic membrane profile, both the abducens internu

242 ) release probability without alterations in postsynaptic membrane properties or changes in glutamate

243 determined by the junctional conductance and postsynaptic membrane properties.

244 eceptors (GluN2B/GluN1) and their associated postsynaptic membrane protein PSD95 were both increased

245 are candidate receptors for neuroligin-1, a postsynaptic membrane protein that can trigger synapse f

246 ot released by exocytosis, and do not act at postsynaptic membrane receptor proteins.

247 d Rotundo report that AChE clustering at the postsynaptic membrane requires perlecan, which binds bot

248 activation of dendritic GABAA receptors, the postsynaptic membrane response changes from hyperpolariz

249 arise through synaptic integration, but the postsynaptic membrane's selectivity for varying levels o

250 ion with immunogold TEM, where expression at postsynaptic membrane sites is clearly observed.

251 pheroidal, pleiomorphic, or ellipsoidal) and postsynaptic membrane specializations (asymmetrical or s

252 itory postsynapses and thus the formation of postsynaptic membrane specializations.

253 egulating the phosphorylation of gephyrin at postsynaptic membrane specializations.

254 ed in spines and formed clusters at distinct postsynaptic membrane subareas.

255 relocation of AMPA receptor/channels in the postsynaptic membrane such that they become more closely

256 NTs adhere to the postsynaptic membrane surface whenever the ligand-bindin

257 tations in gtx lead to drastic reductions in postsynaptic membrane surface, whereas gtx upregulation

258 pse formation, including organization of the postsynaptic membrane, synapse-specific transcription, a

259 l as peak localization further away from the postsynaptic membrane than PSD-95.

260 lex assembly of proteins associated with the postsynaptic membrane that organizes neurotransmitter re

261 ography and subtomogram averaging of Torpedo postsynaptic membrane that receptors are connected by up

262 itic spine proliferation may be to elaborate postsynaptic membrane, thereby increasing the target are

263 winning" inputs by regional reinforcement of postsynaptic membrane to mediate size and strength of co

264 level below that required to depolarize the postsynaptic membrane to relieve Mg(2+) blockade of NMDA

265 hanism by which DFz2 is transported from the postsynaptic membrane to the postsynaptic nucleus during

266 evolved from them being companionless in the postsynaptic membrane to them being the hub of dynamic s

267 AP79/150 and PKA-RII, but not PP2B/CaN, from postsynaptic membranes to the cytoplasm in hippocampal s

268 Postsynaptic membrane trafficking plays an important rol

269 icles within dendrites, suggesting a role in postsynaptic membrane trafficking.

270 eceptor down-regulation and other aspects of postsynaptic membrane turnover.

271 icking of AMPA receptors into and out of the postsynaptic membrane underlies changes in synaptic stre

272 le at the synapse, which is recruited to the postsynaptic membrane upon NMDA receptor activation, and

273 nternalization of glutamate receptors at the postsynaptic membrane via clathrin-mediated endocytosis

274 ptor (AChR) is specifically clustered in the postsynaptic membrane via interactions with rapsyn and o

275 nce of cannabinoid receptor agonist when the postsynaptic membrane was depolarized during the LTP or

276 synthesized and recycled receptors into the postsynaptic membrane were depressed.

277 nk ASIC1a to a macromolecular complex in the postsynaptic membrane where it regulates ASIC1a activity

278 system, ion channel receptors reside in the postsynaptic membrane where they are juxtaposed to presy

279 osphatase PP2B and protein kinase C (PKC) to postsynaptic membranes where they facilitate the phospho

280 ceptors (NMDARs) are stably expressed at the postsynaptic membrane, where they act via Ca(2+) to sign

281 and alpha 5 subunits are concentrated in the postsynaptic membrane, whereas alpha-bungarotoxin recept

282 ntration of glycine receptors (GlyRs) in the postsynaptic membrane, which is crucial for efficient gl

283 otein-enriched cellular compartments beneath postsynaptic membranes, which constantly exchange their

284 concentric toroidal deformations of pre- and postsynaptic membranes, which, because of their unusual

285 This implies a highly organized and stable postsynaptic membrane with tightly anchored receptors.