ライフサイエンスコーパス: postsynaptic site

1 resynaptic membrane is still attached to the postsynaptic site.

2 namically from either the presynaptic or the postsynaptic site.

3 ion in SOD1(G93A) developing networks at the postsynaptic site.

4 ve suggested that they can also modulate the postsynaptic site.

5 ls begin to atrophy and withdraw from normal postsynaptic sites.

6 transmission to CVNs at both presynaptic and postsynaptic sites.

7 s polarized to dendrites and concentrated at postsynaptic sites.

8 by one presynaptic site diffuses to multiple postsynaptic sites.

9 acetylcholine receptors (nAChRs) to neuronal postsynaptic sites.

10 ta-catenin are also enriched at alpha3-nAChR postsynaptic sites.

11 umin-containing perikarya at cytoplasmic and postsynaptic sites.

12 t of GABAergic transmission at both pre- and postsynaptic sites.

13 eptors are localized to both presynaptic and postsynaptic sites.

14 the trigeminal dorsal horn, particularly at postsynaptic sites.

15 tering of acetylcholine receptors (AChRs) at postsynaptic sites.

16 itter release, the receptors can also occupy postsynaptic sites.

17 d actions on both presynaptic neurons and at postsynaptic sites.

18 l neurons, where it is clustered adjacent to postsynaptic sites.

19 taining for GABA(A) receptors (GABA(A)Rs) at postsynaptic sites.

20 rites rarely contained MOR1 at both pre- and postsynaptic sites.

21 is selectively targeted to specific pre- and postsynaptic sites.

22 tes, but localizes specifically to activated postsynaptic sites.

23 ne heads via its ability to recruit Homer to postsynaptic sites.

24 tal NMDA receptors between intracellular and postsynaptic sites.

25 egulate synaptic activity from both pre- and postsynaptic sites.

26 they may regulate processes at both pre- and postsynaptic sites.

27 including the SH3 domain for localization to postsynaptic sites.

28 nnels may be important for recruiting PKA to postsynaptic sites.

29 MPA receptors clustered at these presumptive postsynaptic sites.

30 are concentrated and immobilized at specific postsynaptic sites.

31 ceptors, and potential anchoring proteins at postsynaptic sites.

32 claim a further proportion of the denervated postsynaptic sites.

33 NO relative to NMDA receptors at pre- versus postsynaptic sites.

34 assembly of signal transduction complexes at postsynaptic sites.

35 of PMNs via distinct mechanisms at pre- and postsynaptic sites.

36 calcium and protein messengers initiated at postsynaptic sites.

37 mediated transmission at presynaptic than at postsynaptic sites.

38 ceptors by cytoplasmic proteins at GABAergic postsynaptic sites.

39 ding calcium-permeable AMPA receptors at PVN postsynaptic sites.

40 oteins are known that function at inhibitory postsynaptic sites.

41 the positioning and clustering of AMPARs at postsynaptic sites.

42 hat NL1 regulates the abundance of NMDARs at postsynaptic sites.

43 s, striatal CD73 is prominently localized to postsynaptic sites.

44 calized in high-density clusters at specific postsynaptic sites.

45 density 93 (PSD-93) is a protein enriched at postsynaptic sites.

46 ansporter 2, are colocalized at the presumed postsynaptic sites.

47 with specializations indicative of pre- and postsynaptic sites.

48 tion and sensitivity at both presynaptic and postsynaptic sites.

49 o are concentrated in dendrites, spines, and postsynaptic sites.

50 sing divergence from multisynapse boutons to postsynaptic sites.

51 aptic terminals and for hyperpolarization at postsynaptic sites.

52 is sufficient to redistribute proteasomes to postsynaptic sites.

53 glutamate spillover to adjacent receptors at postsynaptic sites.

54 of acetylcholine receptor (AChR) density at postsynaptic sites.

55 dGRIP, a Wg-receptor-interacting protein, to postsynaptic sites.

56 cumulates at, and adjacent to, glutamatergic postsynaptic sites.

57 egulate neurotransmitter receptor density at postsynaptic sites.

58 trafficking to favor receptor insertion into postsynaptic sites.

59 -R number is gradually reduced at individual postsynaptic sites.

60 can be derived from presynaptic, as well as postsynaptic, sites.

61 a clear and consistent spatial relation with postsynaptic sites, (2) a large number of primary affere

62 86 phospho-CaMKII) was also redistributed to postsynaptic sites after D4 receptor stimulation.

63 rt a novel mechanism for targeting CaMKII to postsynaptic sites after neuronal activation.

64 RESes may increase translation efficiency at postsynaptic sites after synaptic activation.

65 ceptors, a subset of which are segregated to postsynaptic sites after synaptogenesis.

66 The NGF target is localized at a postsynaptic site and involves a new TrkA-like receptor.

67 how regenerative potentials initiate at the postsynaptic site and propagate decrementally toward the

68 ion of the Pyk2-Src signaling pathway at the postsynaptic site and reveals a physiological function o

69 lation increases GluR1 surface expression at postsynaptic sites and amplitudes of EPSCs and mEPSCs in

70 -type Ca(2+) channels which are clustered at postsynaptic sites and are important regulators of neuro

71 anus toxin, GDNF, and BDNF are released from postsynaptic sites and are internalized by afferent pres

72 dies reveal that Mind bomb-2 is localized to postsynaptic sites and colocalizes with the NMDAR in api

73 protein that recruits glutamate receptors to postsynaptic sites and facilitates signal processing and

74 distinct mechanisms, with group-I acting at postsynaptic sites and group-II and group-III acting at

75 t dendritic mRNA is found in the vicinity of postsynaptic sites and provide additional evidence that

76 f Ca(2+)-dependent plasticity at neighboring postsynaptic sites and provides a postsynaptic mechanism

77 ically, one axon withdrew progressively from postsynaptic sites and the competing axon extended axona

78 the submembrane scaffold protein gephyrin to postsynaptic sites, and for postsynaptic function of GAB

79 al or complete withdrawal of axons from some postsynaptic sites, and fragmentation of the postsynapti

80 els are localized on the plasma membrane, at postsynaptic sites, and in association with NMDA recepto

81 ptors, results in recruitment of gephyrin to postsynaptic sites, and restores the amplitude and frequ

82 ovide evidence that ACh destabilizes nascent postsynaptic sites, and that one major physiological rol

83 riatonigral neurons, acting at both pre- and postsynaptic sites, and that the relative contributions

84 tory actions of GABA at both presynaptic and postsynaptic sites, and this may be one set of mechanism

85 rs, which are often present at both pre- and postsynaptic sites, appear to follow an independent deve

86 of the alpha7 nAChR subtype to both pre- and postsynaptic sites appeared to be required to induce thi

87 sence of dNesp1, mRNAs normally localized at postsynaptic sites are lacking and synaptic maturation i

88 ut the mechanisms that target mRNAs to these postsynaptic sites are not well understood.

89 After partial deafferentation postsynaptic sites are reinnervated by local sprouting o

90 tropic glutamate 5 receptors, present at the postsynaptic site, are coupled to Galphaq/11 proteins an

91 matodendritic domain and its clustering near postsynaptic sites, are mediated by distinct molecular m

92 ased size and reduced apposition of pre- and postsynaptic sites, are observed in FE65/FE65L1-DKO mice

93 nsporters, especially those localized at the postsynaptic sites, are responsible for the observed eff

94 his inhibition was mediated at both pre- and postsynaptic sites as evidenced by a dual decrease in th

95 In neurons, CPEB is detected at postsynaptic sites, as well as in the cell body.

96 yrin-immunoreactive clusters were located at postsynaptic sites at both early and late postnatal ages

97 data suggest that, in similarity to pre- and postsynaptic sites at chemical synapses, one side in ele

98 ulating the recruitment of AMPA receptors to postsynaptic sites at excitatory synapses.

99 may coordinate maturation of presynaptic and postsynaptic sites at inhibitory synapses.

100 by which rapsyn is inserted and retained at postsynaptic sites at the neuromuscular junction (NMJ) i

101 oad tracks," that span from muscle nuclei to postsynaptic sites at the neuromuscular junction in Dros

102 robability (Pr) presynaptic sites coupled to postsynaptic sites bearing GluN2B-containing NMDA recept

103 s in the mechanisms of receptor anchoring at postsynaptic sites, both regarding the anchoring of a si

104 ited alpha6(GBS)beta3delta(GBS) receptors to postsynaptic sites but failed to rescue synaptic GABAerg

105 ABA(B) R1 and GABA(B) R2 at various pre- and postsynaptic sites, but also raise the possibility that

106 creased synaptic strength at presynaptic and postsynaptic sites by increasing both quantal release an

107 PKA is recruited to postsynaptic sites by the A kinase anchor protein AKAP15

108 and reorganization of motor endplates at the postsynaptic sites compared with those from PBS-treated

109 Synaptic integration at postsynaptic sites determines neuronal outputs in the CN

110 tory neurotransmission, and their density at postsynaptic sites determines synaptic strength.

111 dendrites and a second that sequesters it at postsynaptic sites; different protein interactions motif

112 irement for TrkB at both the presynaptic and postsynaptic sites during development.

113 g the transport of mRNAs from the nucleus to postsynaptic sites during synaptic maturation.

114 ylcholine receptors (AChRs) at corresponding postsynaptic sites during the process of synapse elimina

115 Focal glutamate application at individual postsynaptic sites evoked currents (I(glu)) with little

116 but not learning, suggesting presynaptic and postsynaptic sites for memory formation.

117 ese results suggest the presence of separate postsynaptic sites for the induction of LTD and accommod

118 eptors are targeted to functionally distinct postsynaptic sites from alpha1-receptors, we conclude th

119 Whereas numerous components of excitatory postsynaptic sites have been identified, relatively few

120 Aside from 'unsilencing' the postsynaptic site, however, the significance of postsyna

121 ulate translation of specific transcripts at postsynaptic sites in an activity-dependent manner.

122 etylcholine receptor (nAChR) localization at postsynaptic sites in avian ciliary ganglion neurons in

123 and also revealed the presence of mGluR7a at postsynaptic sites in both of these regions.

124 show that caspase-3 activity is regulated at postsynaptic sites in brain following stimuli associated

125 e epilepsy model, KARs were not recruited to postsynaptic sites in C1ql2/3 double-null mice, leading

126 atergic transmission at both presynaptic and postsynaptic sites in CeA, and glutamatergic synapses in

127 ranslocation of alpha-CaMKII from cytosol to postsynaptic sites in cultured PFC neurons.

128 m rat forebrain and is localized adjacent to postsynaptic sites in dendritic spines in rat hippocampa

129 opic glutamate receptors are concentrated at postsynaptic sites in excitatory synapses.

130 e II), an abundant protein kinase located at postsynaptic sites in glutamatergic synapses.

131 We used a genetic method to label pre and postsynaptic sites in granule neurons and observed a ste

132 lement binding protein 1 (CPEB-1) resides at postsynaptic sites in hippocampal neurons in which it co

133 Whereas PSD-95 and PSD-93 occur only at postsynaptic sites in hippocampal neurons, SAP-102 also

134 opening, NR2A is encountered infrequently at postsynaptic sites in layer 4, but it increases sharply

135 functional nAChR subtypes at presynaptic and postsynaptic sites in LHb, through which nicotine could

136 hesis have highlighted the potential role of postsynaptic sites in modulation of cell-cell communicat

137 eurotransmitter receptors are immobilized at postsynaptic sites in neurons are largely unknown.

138 hin is found at the muscle sarcolemma and at postsynaptic sites in neurons.

139 GluD2 receptor is a fundamental component of postsynaptic sites in Purkinje neurons, and is required

140 sicles are recruited to both presynaptic and postsynaptic sites in response to increased neuronal act

141 ng approaches to identify pathways and their postsynaptic sites in the amygdala in rhesus monkeys, we

142 otein and NSY-1/ASK1 MAPKKK, is localized to postsynaptic sites in the AWC axons for this lateral int

143 rophin glycoprotein complex found at certain postsynaptic sites in the brain.

144 local axons is unable to reinnervate all the postsynaptic sites in the denervated outer dentate molec

145 KARs are found at both pre- and postsynaptic sites in the dorsal horn.

146 ERG K(+) channels localize to postsynaptic sites in the egg-laying muscle, and mutants

147 e 5 G-protein beta subunit/R7BP complexes at postsynaptic sites in unison with increased signaling de

148 tamate receptors (GluRs) are concentrated at postsynaptic sites in vivo and in vitro.

149 5-based protein complex is trafficked to the postsynaptic site is unknown but presumably involves spe

150 ory LTP, the increase of gephyrin density at postsynaptic sites is associated with the promoted forma

151 acid receptors (GABAARs) at the appropriate postsynaptic sites is critical for determining the effic

152 g and localization of glutamate receptors at postsynaptic sites is poorly understood.

153 neurotransmitter receptor immobilization at postsynaptic sites is poorly understood.

154 as a presynaptic organizer released from the postsynaptic site, it seems possible that postsynaptic S

155 Although AMPARs are clustered at postsynaptic sites like Cav1.2, beta2AR association with

156 calization of protein synthetic machinery at postsynaptic sites makes it possible for the synthesis o

157 smission is difficult to measure because the postsynaptic sites may be distributed along a tortuous d

158 ivity-dependent incorporation of CaMKII into postsynaptic sites may play a role in maturation and pla

159 n of this translational signaling pathway at postsynaptic sites may provide a mechanism that controls

160 roligins-1, -3, and -4 localize to glutamate postsynaptic sites, neuroligin-2 localizes primarily to

161 rules of organization at presynaptic versus postsynaptic sites (nociceptive afferent terminals vs in

162 component of the EPSC was seen, confirming a postsynaptic site of action of aniracetam.

163 Together, these data suggest a postsynaptic site of action.

164 d by diethyl-lactam, again consistent with a postsynaptic site of action.

165 cadmium and nickel, consistent with a direct postsynaptic site of action.

166 Paired-pulse stimuli indicated a postsynaptic site of action.

167 n the presence of tetrodotoxin, suggesting a postsynaptic site of action.

168 ctive translocation of VAPB protein onto the postsynaptic site of C-boutons that altered the morpholo

169 C1a also affected the density of spines, the postsynaptic site of most excitatory synapses.

170 application, indicating both presynaptic and postsynaptic sites of action for ethanol.

171 Most NMDAR functions have been ascribed to postsynaptic sites of action, but there is now an apprec

172 Dendritic spines are postsynaptic sites of excitatory input in the mammalian

173 The function of dendritic spines, postsynaptic sites of excitatory input in the mammalian

174 Dendritic spines are the primary postsynaptic sites of excitatory neurotransmission in th

175 vity; their protein products function at the postsynaptic sites of excitatory synapses.

176 vely regulates the size of dendritic spines--postsynaptic sites of excitatory synaptic transmission.

177 Hence, pre- and postsynaptic sites of expression determine both the sign

178 al evidence that alpha7nAChR is prevalent at postsynaptic sites of glutamatergic synapses in hippocam

179 sions from dendritic shafts that contain the postsynaptic sites of glutamatergic synapses in the brai

180 es AMPA-type glutamate receptors (AMPARs) to postsynaptic sites of glutamatergic synapses.

181 sociated ultrastructural changes at pre- and postsynaptic sites of individual microglomeruli, we empl

182 dynamic, actin-rich structures that form the postsynaptic sites of most excitatory synapses in the br

183 Dendritic spines are the postsynaptic sites of most excitatory synapses in the br

184 The density of dendritic spines, the postsynaptic sites of most excitatory synapses, increase

185 ion-induced translation in germ cells and at postsynaptic sites of neurons.

186 enzyme DGL-alpha colocalized with mGlu(5) at postsynaptic sites of the dlPAG, whereas CB(1) was confi

187 ity of simultaneous imaging of both pre- and postsynaptic sites of the dopaminergic system in baboons

188 r ligand co-injected to assess both pre- and postsynaptic sites of the dopaminergic system simultaneo

189 Dendritic spines are the postsynaptic sites of the majority of excitatory synapse

190 abnormal morphology of dendritic spines, the postsynaptic sites of the majority of excitatory synapse

191 subtype, the sst2A receptor, is localized at postsynaptic sites of the principal neurons where it mod

192 GABA(C) receptors and MAP-1B co-localize at postsynaptic sites on bipolar cell axon terminals.

193 e receptors, but not glutamate receptors, at postsynaptic sites on central neurons.

194 Polyribosomal complexes beneath postsynaptic sites on dendrites provide a substrate for

195 Excitatory postsynaptic sites on dendritic spines contained a high

196 pulation of iAChRs specifically localized at postsynaptic sites on inhibitory motor neurons.

197 complexes are selectively localized beneath postsynaptic sites on neuronal dendrites; this localizat

198 AMPA vs NMDA receptors) at a single class of postsynaptic sites on pyramidal cell dendritic spines.

199 A receptors that are mobilized to functional postsynaptic sites on the plasma membrane by afferent in

200 We find matching dynamics among postsynaptic sites on the principal neurons receiving th

201 bly or removal) of excitatory and inhibitory postsynaptic sites on the same neurons in mouse visual c

202 e rat entorhinal cortex are mobile at either postsynaptic sites or in presynaptic terminals.

203 nt in both presynaptic axon terminals and at postsynaptic sites, primarily dendrites.

204 of different subunit composition to specific postsynaptic sites, providing a mechanism to increase th

205 P-induced nociceptive responses primarily at postsynaptic sites, rather than through inhibition of SP

206 ophies when dysfunctional, has a function at postsynaptic sites restricted to a subset of GABAergic i

207 gh they did exhibit a decrease in excitatory postsynaptic sites, suggesting that synapse loss may be

208 v2.1 subunit-containing channels at specific postsynaptic sites suggests that this family of voltage-

209 ve distribution of MORs to specific pre- and postsynaptic sites suggests the receptor may be selectiv

210 ponse to the peptide at both presynaptic and postsynaptic sites, suggests that the peptide probably m

211 Effects were specific to alpha3-nAChR postsynaptic sites; synaptic glycine receptor and perisy

212 otagmin and active zone markers, adjacent to postsynaptic sites that have aggregates of glutamate IIA

213 At postsynaptic sites, the PDZ scaffolds are essential for

214 eeds back to activate NMDAR at corresponding postsynaptic sites through increased neurotransmitter re

215 be involved in localizing AMPA receptors at postsynaptic sites through its interaction with the GluR

216 by recruiting intracellular vesicles toward postsynaptic sites through the interaction with synbindi

217 MeHg apparently acts at both presynaptic and postsynaptic sites to alter GABA(A) receptor-mediated in

218 MeHg apparently acts at both presynaptic and postsynaptic sites to alter GABAA receptor-mediated inhi

219 nsducing proteins of both glutamate and GABA postsynaptic sites to either the microtubule or microfil

220 , nicotine acts at different presynaptic and postsynaptic sites to facilitate glutamatergic neurotran

221 Thus, chapsyn-110 and PSD-95 may interact at postsynaptic sites to form a multimeric scaffold for the

222 y generating H(2)O(2) that must diffuse from postsynaptic sites to inhibit presynaptic DA release via

223 alpha (CaMKII), sequentially translocates to postsynaptic sites, undergoes autophosphorylation and ge

224 receptor-deficient mice, but not in the PFC (postsynaptic site), using a viral gene-delivery approach

225 their roles in the assembly of glutamatergic postsynaptic sites, we studied the distributions of NMDA

226 which they regulate receptor populations at postsynaptic sites, we utilized electron tomography to e

227 We now show that endogenous tau is found at postsynaptic sites where it interacts with the PSD95-NMD

228 ed in the brain, and are present at pre- and postsynaptic sites where they play a prominent role in s

229 n is a key site for recruiting CaMKII to the postsynaptic site, where it may act in concert with calm

230 /Calmodulin-dependent Kinase II (CaMKII), to postsynaptic sites, where it is rapidly translated.

231 eta proteins were localized to glutamatergic postsynaptic sites, where they interacted with the NMDAR

232 I mGluRs and provide various presynaptic and postsynaptic sites whereby mGluR1 and mGluR5 could media

233 of mitochondria relative to presynaptic and postsynaptic sites, whether mitochondria are dynamically

234 DOR immunoreactivity was located at postsynaptic sites within neuronal perikarya (2%), dendr

235 KOR immunoreactivity was found at pre- and postsynaptic sites within the RVM of both sexes.

236 f MEF2C results in a reduction of excitatory postsynaptic sites without affecting learning and memory