ライフサイエンスコーパス: postsynaptically

1 I mGluR-LTD appears to be expressed entirely postsynaptically.

2 e zone domains remains intact, both pre- and postsynaptically.

3 dulation can occur either presynaptically or postsynaptically.

4 ynaptically at PF synapses, LTD is expressed postsynaptically.

5 sticity is thought to be primarily generated postsynaptically.

6 s that not all NMDA-dependent LTP is induced postsynaptically.

7 alpha is localized at synapses both pre- and postsynaptically.

8 citability of central synapses both pre- and postsynaptically.

9 synaptic clefts, and simpler secondary folds postsynaptically.

10 that the block of synaptic responses occurs postsynaptically.

11 ynapse and that it is required both pre- and postsynaptically.

12 at this type of LTD is most likely expressed postsynaptically.

13 ing average frequency are presented pre- and postsynaptically.

14 ACh quanta summate linearly postsynaptically.

15 rns emerge presynaptically and are reflected postsynaptically.

16 ion channels and transporters both pre- and postsynaptically.

17 that sensitivity to convulsions is mediated postsynaptically.

18 ase inhibitor, did not block the NT-3 effect postsynaptically.

19 ceptors are located both presynaptically and postsynaptically.

20 that ended on type II cells pre- as well as postsynaptically.

21 s, and (3) alpha 2AAR operates both pre- and postsynaptically.

22 ilar neurons and granule cells both pre- and postsynaptically.

23 ciated with glutamatergic terminals pre- and postsynaptically.

24 ed enhancement of excitability both pre- and postsynaptically.

25 tion and variance, suggesting that CGRP acts postsynaptically.

26 hair cells where it may be localized pre- or postsynaptically.

27 tic density preparation that LRP1 is located postsynaptically.

28 ht-gated mammalian iGluR6 (LiGluR) expressed postsynaptically.

29 pontaneous neurotransmitter release detected postsynaptically.

30 lize to synapses in CA1 and are concentrated postsynaptically.

31 naptically, but are thought to be excitatory postsynaptically.

32 tor presynaptically and a negative regulator postsynaptically.

33 napses, is PICK1 dependent, and is expressed postsynaptically.

34 protein is present both presynaptically and postsynaptically.

35 unction in the endocytosis of AMPA receptors postsynaptically.

36 ity of quantal amplitudes determined pre- or postsynaptically?

37 gic and glutamatergic synapses both pre- and postsynaptically; 2) Pcdh-gammaC5 is also extrasynaptica

38 to postnatal age, (2) saturable, (3) induced postsynaptically, (4) reversible, and (5) not associated

39 Inhibition of Dscam either pre- or postsynaptically abolishes the emergence of synaptic tra

40 Postsynaptically, ACh receptor clusters are markedly inc

41 Postsynaptically, AChR clusters in HSA-beta-cat(flox(ex3

42 toreceptor function, they may participate in postsynaptically activated short-loop feedback modulatio

43 ) R2 immunoreactivity was commonly expressed postsynaptically, although immunoreactive preterminal ax

44 oup I mGluR subtypes was primarily expressed postsynaptically, although light mGluR1a labeling was oc

45 n-dependent manner while having no effect on postsynaptically (AMPA) evoked currents recorded in the

46 of PKA, but the roles of presynaptically and postsynaptically anchored forms of PKA in late-phase LTP

47 omuscular junction, amphiphysin is localized postsynaptically and amphiphysin mutants have no major d

48 ads to both an increased expression of GluA1 postsynaptically and an increase in vesicle pool size an

49 rdingly, dNedd4Lo was colocalized with dAmph postsynaptically and at muscle T-tubules.

50 us and ACx, we show that TC LTP is expressed postsynaptically and depends on group I metabotropic glu

51 strength in pyramidal cells that is induced postsynaptically and depends on metabotropic glutamate r

52 In adult mouse cortex, ABHD6 was located postsynaptically and its selective inhibition allowed th

53 tablishing that 5-HT2A receptors are located postsynaptically and presynaptically, (ii) demonstrating

54 utamatergic neurotransmission by acting both postsynaptically and presynaptically.

55 The synaptic potentiation occurs postsynaptically and probably involves up-regulation of

56 IgSF21 localizes postsynaptically and recruits axonal neurexin2alpha in a

57 factor attachment protein receptors (SNAREs) postsynaptically and that nicotinic stimulation rapidly

58 ition was GABA-mediated, acted both pre- and postsynaptically and was fast enough to either prevent o

59 n the plasma membranes of LC neurons pre- or postsynaptically and whether there is differential relea

60 E2's acute effect was mediated postsynaptically, and required Ca(2+) influx through the

61 A Y1 receptor activates a K+ current postsynaptically, and several receptor types appear to i

62 naptic transmission both presynaptically and postsynaptically, and this could be independent of ASICs

63 In addition, GluR6-KARs, localizing pre- and postsynaptically, are critically involved in inhibiting

64 Moreover, this lipase accumulates postsynaptically around afferent excitatory synapses in

65 ically as a decrease in transmitter release, postsynaptically as a decrease in the synaptic current e

66 uronal information storage that is expressed postsynaptically as a functional down-regulation of alph

67 membrane ligand for Eph receptors, functions postsynaptically as a receptor to transduce reverse sign

68 r striatal LTD is thus likely to be released postsynaptically as a retrograde messenger.

69 hat MHCI proteins were present both pre- and postsynaptically at all ages examined.

70 hat fusion-competent Syt 4 vesicles localize postsynaptically at both neuromuscular junctions (NMJs)

71 y at axon terminals and initial segments and postsynaptically at dendritic spines and shafts.

72 erotonergic changes both presynaptically and postsynaptically at four different motor states (baselin

73 n kinase II (CaM kinase II) are concentrated postsynaptically at glutamatergic synapses on glutamater

74 2 subunits are localized presynaptically and postsynaptically at mossy fiber synapses where they most

75 he intermediate filament nestin is localized postsynaptically at rodent neuromuscular junctions.

76 t alpha7nAChR allows for activation of NMDAR postsynaptically at synapses lacking AMPAR.

77 tingly, we observed that GluR1 was expressed postsynaptically at the climbing fibers (CF) synapse at

78 hat Cortactin is present presynaptically and postsynaptically at the Drosophila NMJ and that it is a

79 ophila Hts/Adducin is enriched both pre- and postsynaptically at the NMJ.

80 ynaptically, at glutamatergic terminals, and postsynaptically, at apical dendrites, without inhibitin

81 It is concluded that cannabinoids may postsynaptically augment the excitability of CA1 pyramid

82 l ligand for neurexins that may be localized postsynaptically based on its well characterized interac

83 These differences might arise postsynaptically because of differential postsynaptic at

84 alizes both at the presynaptic terminals and postsynaptically, being frequently localized on the syna

85 Here we demonstrate that adaptation begins postsynaptically but is ultimately communicated to presy

86 asymmetric synapses (n = 70) (both pre- and postsynaptically but predominantly in the postsynaptic e

87 synaptic physiology both presynaptically and postsynaptically, but the regulatory mechanisms remain o

88 a-opioid receptor (KOR) is detected pre- and postsynaptically, but the subcellular localization, tran

89 2+) entry through N-type Ca(2+) channels and postsynaptically by acetylcholine acting on nicotinic re

90 This potentiation was expressed postsynaptically by AMPA-type glutamate receptors and re

91 ine GABAergic system that exerts its effects postsynaptically by inhibiting NPO neurons, resulting in

92 In the model, slow responses, generated postsynaptically by mGluR-mediated phosphoinositide hydr

93 es indicate that these changes are regulated postsynaptically by neuropeptide Y (NPY), an adrenal cot

94 ed by excessive excitation may be determined postsynaptically by the way in which different target ce

95 he RecA(Ec) protein strand exchange reaction postsynaptically, by binding to the displaced single str

96 Postsynaptically, CAM II kinase-alpha immunoreactivity w

97 ow that a nitric oxide (NO) signal generated postsynaptically can regulate endocytosis and at least o

98 Postsynaptically, changes in synaptic strength can occur

99 ory neurotransmission in the BLA-CeL pathway postsynaptically, consistent with the known roles of PAC

100 s that drive Fas II expression both pre- and postsynaptically; driving Fas II expression on either si

101 t the hypothesis that, despite being induced postsynaptically, DSI is expressed presynaptically as a

102 How LTP, induced postsynaptically, engages these extracellular traffickin

103 Here we report that MINK and TNIK are postsynaptically enriched proteins whose clustering with

104 in the tractus solitarius (ts) and currents postsynaptically evoked by alpha-amino-3-hydroxy-4-isoxa

105 This treatment predominantly increased postsynaptically excitatory synaptic transmission.

106 postsynaptic 5-HT1A receptors; and (3) 5-HT postsynaptically excites pallidal neurons through activa

107 This LTP is postsynaptically expressed and requires activation of an

108 onstrated that functional NMDA receptors are postsynaptically expressed at climbing fiber (CF) to Pur

109 The discovery of a postsynaptically expressed form of cerebellar parallel f

110 Here, we show that postsynaptically expressed LTP is induced selectively in

111 to the patch-pipette saline, suggesting that postsynaptically expressed NMDA receptors are required f

112 This LTP is postsynaptically expressed, enhanced by chelating postsy

113 BAPTA applied postsynaptically failed to block the action of nicotine

114 vermectin sensitivity on worms, is necessary postsynaptically for a functional M3 synapse and for the

115 rve and muscle and is required both pre- and postsynaptically for normal synaptic growth.

116 in, neither Liprin-alpha nor LAR is required postsynaptically for R cells to project to their correct

117 showed that Fas II is required both pre- and postsynaptically for synaptic stabilization.

118 genesis in vitro and in vivo and is required postsynaptically for thrombospondin- and astrocyte-induc

119 s on presynaptic terminals and to GluRdeltas postsynaptically, forming trans-synaptic triads that pro

120 spinal cord, endocannabinoids are mobilized postsynaptically from network neurons and act retrograde

121 neuronal activation glutamate is transported postsynaptically from synaptic clefts and increased lact

122 d receptivity and to induce the formation of postsynaptically functioning CNS synapses.

123 Postsynaptically, Hcrt/Orx produced an inward current an

124 uired for neuronal communication is consumed postsynaptically, i.e., at the target neurons.

125 Postsynaptically, i.e., in striatal neurons, D2R signali

126 hether receptors located presynaptically and postsynaptically in a single cell type display different

127 ns, presynaptically in the granule cells and postsynaptically in CA1 pyramidal cells.

128 evidence that alpha2C-ARs (1) are localized postsynaptically in catecholaminergic neurons of the LC

129 KARs were distributed both postsynaptically in dendrites and somata (51% of GluR5,6

130 oth receptor subtypes is primarily expressed postsynaptically in dendrites and spines, although presy

131 subpopulation of glutamatergic terminals and postsynaptically in dendrites and spines.

132 ns presynaptically while the other functions postsynaptically in forming the channels.

133 LC-3 channels regulate neuronal excitability postsynaptically in immature neurons.

134 ereas L-type channels were found exclusively postsynaptically in neuronal elements.

135 e receptor, mGluR1 and mGluR5, are expressed postsynaptically in neurons of the subthalamic nucleus (

136 essed in the brain and present both pre- and postsynaptically in neurons.

137 the owl and the chicken, Kv3.1 was targeted postsynaptically in NM and NL.

138 ssing cells, suggesting that MC4-Rs function postsynaptically in some instances and may function pres

139 basal expression occurs presynaptically and postsynaptically in spinal dorsal horn.

140 I mGluRs (mGluR1a and mGluR5) are localized postsynaptically in the dendrites of STN neurons.

141 inergic and catecholaminergic terminals, (2) postsynaptically in the dendritic spines of pyramidal an

142 zed pre- and postsynaptically in the OPL and postsynaptically in the IPL.

143 We find that Babo signaling is required postsynaptically in the muscle, in contrast to the well-

144 owed that the receptor is localized pre- and postsynaptically in the OPL and postsynaptically in the

145 al that both mGuR1a and mGluR5 are localized postsynaptically in the SNr.

146 ellar cortex, where PMCA2a also concentrates postsynaptically, in the spines of Purkinje cells.

147 ere, we report that overexpression of Bcl-xL postsynaptically increases frequency and amplitude of sp

148 Bcl-xL, overexpressed either pre or postsynaptically, increases synapse number, the number a

149 sion (LTD) at the corticostriatal synapse is postsynaptically induced but presynaptically expressed,

150 enhancement of presynaptic facilitation and postsynaptically induced long-term potentiation.

151 It is almost axiomatic in neuroscience that postsynaptically induced NMDA-dependent long-term potent

152 gly, both types of afferent can also undergo postsynaptically induced NMDA-receptor-dependent LTP.

153 cate that 5-HT-containing axon terminals may postsynaptically inhibit GABAergic neurons and their tar

154 ded hypoglossal motoneurons were found to be postsynaptically inhibited on the basis of analyses of t

155 tropic glutamate receptor type 6 (mGluR6) is postsynaptically localized and expressed only in the den

156 Recent reports have revealed that postsynaptically localized ASICs contribute to the excit

157 Our results suggest that PGE2 synthesized by postsynaptically localized COX-2 functions as a retrogra

158 Together, these results suggest that postsynaptically localized MHCl acts in homeostatic regu

159 em, we demonstrate that neuroligin-1 and -2, postsynaptically localized proteins, can trigger the de

160 Neurogranin (Ng) is a brain-specific, postsynaptically located protein kinase C (PKC) substrat

161 initiates mechanistically distinct forms of postsynaptically maintained LTD and these LTDs are diffe

162 m2 receptors that are located both pre- and postsynaptically mediate many cholinergic effects in the

163 Although SCs express CB1Rs postsynaptically, neither high-frequency firing of SCs n

164 ily of synaptic scaffolding proteins located postsynaptically on excitatory synapses.

165 and 5-HT(2)Rs are thought to be located only postsynaptically on IO cells.

166 central melanocortins act presynaptically or postsynaptically on MC4-Rs is also unknown.

167 eurons and by delta opioid receptors located postsynaptically on pallidostriatal feedback neurons.

168 b and GABA(B)R2 were more strongly expressed postsynaptically on pyramidal and nonpyramidal cells tha

169 unctional GluK1-containing KARs were present postsynaptically on VP neurons but not on OT cells.

170 jor proportion of GABA(B)Rs may be expressed postsynaptically or on GABAergic terminals.

171 l synapses in which it was expressed pre- or postsynaptically, or both, in spinal laminae I-IV.

172 his plasticity is expressed presynaptically, postsynaptically, or both.

173 gh synaptic NMDARs are predominately located postsynaptically, recent evidence suggests that they may

174 m) decreases neocortical network activity by postsynaptically reducing excitatory synaptic transmissi

175 ontrol synaptic growth and axon guidance and postsynaptically regulate endocytosis of glutamate recep

176 the CNS and are present presynaptically and postsynaptically regulating synaptic transmission and ex

177 ression of wild-type Gs alpha either pre- or postsynaptically rescued the mutational defects in bouto

178 synapses that are presynaptically active but postsynaptically silent and work in concert with other,

179 functional AMPA receptors and are therefore postsynaptically silent at resting membrane potentials.

180 Our results confirm the existence of postsynaptically silent synapses and demonstrate that th

181 and ion channels) and the transformation of postsynaptically silent synapses into functional ones.

182 SCs, suggesting the selective enhancement of postsynaptically silent synapses upon inactivation of al

183 physiological evidence for the existence of postsynaptically silent synapses.

184 structural synapses, but these synapses are postsynaptically silent.

185 Many excitatory synapses are thought to be postsynaptically 'silent', possessing functional NMDA bu

186 rtate receptor) and CaMKII signalling and on postsynaptically synthesized BDNF.

187 Postsynaptically, T-588 reduced acetylcholine currents a

188 anterograde transsynaptic tools for tagging postsynaptically targeted neurons remain under developme

189 l axons formed a normal whisker map, whereas postsynaptically the cytoarchitecture of layer IV neuron

190 ic plasticity can be expressed both pre- and postsynaptically, the functional consequences of this ar

191 Postsynaptically, the muscarinic acetylcholine receptor

192 Postsynaptically, the opioids activate a potassium condu

193 Although the receptors can act both pre- and postsynaptically, their physiological significance is un

194 that HSPGs function both presynaptically and postsynaptically; these defects could be rescued by appr

195 released, mature TC synapses can express LTD postsynaptically through group I metabotropic glutamate

196 t fasting and leptin act presynaptically and postsynaptically to alter GABAergic drive to GnRH neuron

197 e NPY receptors act both presynaptically and postsynaptically to depress GABA-mediated Ca2+ rises.

198 Synaptic input may cause Ca(2+) accumulation postsynaptically to evoke a Ca(2+)-activated inward curr

199 tivated non-specific cation current (I(CAN)) postsynaptically to generate 10-30 mV transient depolari

200 y to inhibit sensory transmitter release and postsynaptically to inhibit motor neuron excitability.

201 The DinD protein, however, acts postsynaptically to inhibit RecA during an on-going DNA

202 ically to promote normal synaptic growth and postsynaptically to maintain normal levels of evoked tra

203 to act through TrkB presynaptically, but not postsynaptically, to modulate LTP.

204 hat Dnlg2 functions both presynaptically and postsynaptically together with Neurexin to determine the

205 lly strong lateral inhibition, both pre- and postsynaptically, triggered by distant motion.

206 Postsynaptically, TrkB controls the localization of a sc

207 In this model, the LGMD multiplies postsynaptically two inputs (one excitatory, one inhibit

208 campal inhibitory synapses that is triggered postsynaptically via glutamate receptor activation but i

209 o trigeminal motoneurons presynaptically and postsynaptically via presynaptic inhibition and by reduc

210 This modulation occurred postsynaptically, was mediated primarily by mGluR5, and

211 iclin II (Fas II) is localized both pre- and postsynaptically where it controls synapse stabilization

212 brane traffic by phosphorylation also occurs postsynaptically, where it contributes to synaptic plast

213 types are found in neurons, both pre- and/or postsynaptically, where they mediate modulatory roles an

214 ppocampal cultures, where it is co-localized postsynaptically with calcium/calmodulin-dependent prote

215 MHCI protein is colocalized postsynaptically with PSD-95 in dendrites of hippocampal

216 ents recorded in serotonergic neurons in DRN postsynaptically, without significantly affecting presyn

217 Traditionally, NMDA receptors are located postsynaptically; yet, putatively presynaptic NMDA recep