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1 for shelterin subunits when TIN2 is depleted posttranslationally.
2 -666 and Cys-673-Cys-685, that was completed posttranslationally.
3 nscriptional level, but it is also regulated posttranslationally.
4 encoded in the genetic code, but synthesized posttranslationally.
5 or Kruppel-like factor 5 (KLF5) is regulated posttranslationally.
6 nifest in the cytoplasmic compartment co- or posttranslationally.
7 that a number of phage proteins are modified posttranslationally.
8 tment fails to occur if the lipids are added posttranslationally.
9 Z regulates the concentration of FlhD(4)C(2) posttranslationally.
10 ains its phospholipid recruitment capability posttranslationally.
11 nslation, whereas the CHIP E3 appears to act posttranslationally.
12 n accumulation by GrIP overexpression occurs posttranslationally.
13 re synthesized in the cytoplasm and imported posttranslationally.
14 are synthesized in the cytosol and imported posttranslationally.
15 M(EL) during TFD, both transcriptionally and posttranslationally.
16 and translocates equally efficiently co- and posttranslationally.
17 I1 ubiquitination and stabilized the protein posttranslationally.
18 d in the stroma and targeted to the membrane posttranslationally.
19 suggesting that Puf3p activity is regulated posttranslationally.
20 In addition, Naa10 can act independently to posttranslationally acetylate a distinct set of substrat
23 demonstrate that purified RimL is capable of posttranslationally acetylating L12, exhibiting a V(max)
24 ntiation in vitro and in vivo and signals to posttranslationally activate myogenic basic helix-loop-h
25 gnaling and TNFalpha release, is rapidly and posttranslationally activated by a variety of signaling
26 anase, overexpressed by glomerular cells and posttranslationally activated by cathepsin L of tubular
27 igand shedding is that it can be rapidly and posttranslationally activated in a manner that requires
28 nscriptional activator for the nif genes, is posttranslationally activated only by the uridylylated f
29 [familial intrahepatic cholestasis 1 (FIC1)] posttranslationally activated the farnesoid X receptor (
30 we showed that Pseudomonas aeruginosa T6S is posttranslationally activated upon phosphorylation of Fh
31 otein also accumulated, and was subsequently posttranslationally activated, during the compatible int
32 peptides, the serine-3 residue of ghrelin is posttranslationally acylated with an n-octanoic acid, a
35 r bridge (sactionine bond) that is installed posttranslationally and is absolutely required for their
37 ins can associate with membranes co- but not posttranslationally, and we perform a structure function
38 revealed that this small GTPase is modified posttranslationally at Ser(76) by a phosphorylcholine mo
41 MP/PKA stimulation regulates CFTR biogenesis posttranslationally, based on predicted 14-3-3 binding m
43 Because channels and gap junctions are gated posttranslationally, bioelectrical networks have their o
44 racting with polypeptide chains both co- and posttranslationally, but it is currently not clear how d
49 suggest that the C-tail domain is recognized posttranslationally by a specialized translocation appar
50 us of the G(N) precursor protein and removed posttranslationally by endoproteolysis, were required fo
51 four same gene products, which are modified posttranslationally by methylation and phosphorylation.
53 mixed-acid fermentation, which is activated posttranslationally by PFL-activating enzyme (PFL-AE).
54 ther, presenilin (PS) regulates Pen-2 levels posttranslationally by preventing its degradation by the
55 biliary damage, PC2 expression is modulated posttranslationally by the proteasome or the autophagy p
58 transgene for MCD (Tg-fMCD(Skel)) stabilized posttranslationally by the small molecule, Shield-1.
59 induce reactivation were tightly controlled posttranslationally by the synthetic hormone tamoxifen.
62 ry loop involving the ER Insig proteins, and posttranslationally, by Insig-dependent protein degradat
63 the 21.5-kD sieve element-specific ENOD are posttranslationally cleaved from the precursor protein,
66 Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins, Gn a
68 e small ubiquitin-like modifiers (SUMOs) are posttranslationally conjugated to eukaryotic cellular pr
69 ated modifiers (SUMOs) are proteins that are posttranslationally conjugated to other cellular protein
70 meostasis whereby an E3 ubiquitin ligase may posttranslationally control components of the transcript
71 n of PaO activity in canola seed was largely posttranslationally controlled and it was at this level
73 and biochemical analyses, we show that FliZ posttranslationally controls HilD to positively regulate
77 bilized and that their alpha-tubulin subunit posttranslationally detyrosinated after engagement of th
78 , enhanced activity of the RTA promoter, and posttranslationally enhanced RTA's trans-activating capa
79 n also be generated through modifications of posttranslationally exposed pro-N-degrons of otherwise s
80 chaperoning the newly synthesized TA protein posttranslationally from the ribosome to the endoplasmic
81 ther clock genes, implying that for dCLOCK a posttranslationally generated rhythm is more important t
82 Peroxisomes are eukaryotic organelles that posttranslationally import proteins via one of two conse
83 lear genome, synthesized in the cytosol, and posttranslationally imported into the organelle in an en
85 we show here that indeed WT SOD1 is modified posttranslationally in sporadic ALS and is iper-oxidized
86 Escherichia coli, chemoselectively modified posttranslationally in the cell-free homogenate, and dir
87 tivation and PER-TIM repression is regulated posttranslationally, in part through rhythmic phosphoryl
89 s suggest that PagL enzymatic deacylation is posttranslationally inhibited by membrane environments,
93 peptides in which the third last residue is posttranslationally isomerized to the d configuration.
94 able a wide diversity of natural, unnatural, posttranslationally modified (methylated, glycosylated,
98 ino acids with three residues of the unusual posttranslationally modified amino acid, 6-bromotryptoph
99 lding of a Conus peptide is facilitated by a posttranslationally modified amino acid, gamma-carboxygl
100 have developed a strategy in which otherwise posttranslationally modified amino acids are genetically
102 a mechanism by which CDC-family proteins are posttranslationally modified and regulated and help expl
104 tly enhanced the kinase activity of Src, and posttranslationally modified at least one additional mem
106 dyscrasias and that dominant inheritance of posttranslationally modified autoantigenic paratargs is
107 agents that are ribosomally synthesized and posttranslationally modified by a multienzyme complex to
111 omegalovirus has been previously shown to be posttranslationally modified by covalent conjugation to
112 hemagglutinin (HA) contains three cysteines, posttranslationally modified by covalently bound fatty a
114 mammalian nuclear lamina protein lamin B1 is posttranslationally modified by farnesylation, endoprote
115 the major autoantigen in Graves' disease, is posttranslationally modified by intramolecular cleavage
116 rvariable C-terminal domain (HVD) of Rabs is posttranslationally modified by isoprenyl moieties that
117 at Lys-392 of the antibiotic-binding site is posttranslationally modified by N(zeta)-carboxylation.
118 licated in regulating the levels of proteins posttranslationally modified by nitric oxide on cysteine
120 The differentially expressed proteins are posttranslationally modified by phosphorylation and glyc
121 e by Western blotting revealed that c-Jun is posttranslationally modified by phosphorylation and its
122 ed that endogenous human and Xenopus BAF are posttranslationally modified by phosphorylation and pote
123 cancer-associated RNA-binding protein La is posttranslationally modified by phosphorylation and sumo
124 a multifunctional regulatory protein that is posttranslationally modified by phosphorylation during v
128 ellular pathogen Listeria monocytogenes, was posttranslationally modified by S-glutathionylation at t
131 isordered regions, and are recognized and/or posttranslationally modified by structured domains of th
133 chemokine receptors CCR5 and CCR2b, CXCR4 is posttranslationally modified by sulfation of its amino-t
140 x virus type 1 (HSV-1) envelope proteins are posttranslationally modified by the addition of sialic a
141 he second extracellular loop of the C3aR are posttranslationally modified by the addition of sulfate.
142 usly, we have demonstrated that ErbB4 ICD is posttranslationally modified by the small ubiquitin-like
143 d that the E. chaffeensis effector TRP120 is posttranslationally modified by ubiquitin (Ub) and that
145 lysine residues at the p53 C terminus can be posttranslationally modified by various mechanisms, incl
146 I molecules can present to the immune system posttranslationally modified cytosolic peptides carrying
149 eal host from which to obtain high levels of posttranslationally modified eukaryotic proteins for x-r
151 iquitin-conjugated tau, suggesting that this posttranslationally modified form of tau may be rapidly
152 phorylate Baf53 in vitro, implying that this posttranslationally modified form relieves the suppressi
153 hat is up-regulated in melanoma represents a posttranslationally modified form, most likely reflectin
156 or 2 in eukaryotes (eEF-2) contains a unique posttranslationally modified histidine residue, termed d
159 nstrate that p53 associated with SV40 LT was posttranslationally modified in a manner consistent with
160 eptor alpha (IFN-gammaR alpha) is stable but posttranslationally modified in herpes simplex virus 1(F
161 at U(S)3 interacts with PDCD4, that PDCD4 is posttranslationally modified in infected cells both in a
165 atic asialoglycoprotein receptor (ASGP-R) is posttranslationally modified in the Golgi en route to th
166 the T cell-attracting chemokine CCL2 can be posttranslationally modified in the tumor microenvironme
169 the absence of a structure for full-length, posttranslationally modified membrane receptors, our app
170 sin-1 is due to its unique ability to select posttranslationally modified microtubules for cargo tran
171 ibrin may function, in part, to downregulate posttranslationally modified MRN complex components afte
173 O by secreting a small ribosomally produced, posttranslationally modified natural product called meth
174 tides are a class of ribosomally synthesized posttranslationally modified natural products found in b
177 e was seen at or near residues that had been posttranslationally modified or at defined secondary str
178 ctions as an epigenetic reader that binds to posttranslationally modified or unmodified histone H3 ta
181 ns belong to the ribosomally synthesized and posttranslationally modified peptide (RiPP) family of na
183 roduce lantibiotics, genetically encoded and posttranslationally modified peptide antibiotics, which
185 Planosporicin is a ribosomally synthesized, posttranslationally modified peptide lantibiotic produce
186 s are a class of ribosomally synthesized and posttranslationally modified peptide natural products (R
188 itides are plant ribosomally synthesized and posttranslationally modified peptides (RiPPs) of various
190 re a subclass of ribosomally synthesized and posttranslationally modified peptides (RiPPs) with compl
192 are a family of ribosomally synthesized and posttranslationally modified peptides containing (methyl
194 antipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioeth
195 veral classes of ribosomally synthesized and posttranslationally modified peptides involves dehydrati
198 on trace levels of phosphorylated and other posttranslationally modified peptides, suggesting that t
200 ed by structural characterization of several posttranslationally modified peptides: IRMPD of phosphor
201 5 and 6 allow the formation of appropriately posttranslationally modified photoreactive peptide probe
202 quantification of differences in protein and posttranslationally modified protein expression levels.
203 on would be beneficial for studies of highly posttranslationally modified protein such as histones.
205 measure the absolute levels of proteins and posttranslationally modified proteins after proteolysis
208 ivo concentrations of metabolites, total and posttranslationally modified proteins, and develop a con
210 novel, recurrent hotspot was identified at a posttranslationally modified residue in the histone H2B
215 postsynaptic terminals, and this abnormally posttranslationally modified tau is enriched in synapton
216 dule in which the sensor receptor protein is posttranslationally modified to attenuate ligand-induced
217 odel for any DNA-binding protein that can be posttranslationally modified to change its affinity for
219 how that the indole side chain of Trp-352 is posttranslationally modified to give mass shifts of +4,
221 protein contained a signal sequence and was posttranslationally modified to produce three hydroxypro
222 lantibiotics use two peptides that are each posttranslationally modified to yield two functionally d
224 1.7 driven by hierarchical interactions with posttranslationally modified versions of the binding par
225 nstrated that the T domain of CmaA, which is posttranslationally modified with a 4'-phosphopantethein
227 at b-type flagellin from strain PAO1 is also posttranslationally modified with an excess mass of up t
228 tes of the prion protein or PrP(C) PrP(C) is posttranslationally modified with N-linked glycans and a
230 a cyclic 26-amino acid (aa) peptide that is posttranslationally modified with one disulfide and one
233 wo experimental models of COPD and increased posttranslationally modified WNT-5A in human COPD tissue
234 d germline-limited genes expressed, and some posttranslationally modified, during genome rearrangemen
236 on initiation have been found to be mutated, posttranslationally modified, or differentially expresse
241 lin, making this antibiotic the most heavily posttranslationally-modified peptide known to date.
242 monstrated that the PARP-1 protein binds and posttranslationally modifies HuR in PARPi-treated PDAC c
243 GLN1) is a key oxygen sensor in mammals that posttranslationally modifies hypoxia-inducible factor al
244 The small ubiquitin-related modifier SUMO posttranslationally modifies many proteins with roles in
245 sociated with receptor tyrosine kinases, and posttranslationally modifies members of the Src family o
246 ons describe a pharmacological strategy that posttranslationally modifies nephrin and the effects of
247 e (OGT) is an essential cellular enzyme that posttranslationally modifies nuclear and cytoplasmic pro
248 ansferase gene from Bacillus subtilis, which posttranslationally modifies polyketide synthase and non
249 ctrophilic species in equilibrium with urea, posttranslationally modifies proteins through a process
250 ases, suggesting that human homologs of NisC posttranslationally modify a cysteine of a protein subst
251 molecule produced by excess NO and that can posttranslationally modify and inactivate proteins, espe
252 e polymers of ADP-ribose (pADPr or PAR) that posttranslationally modify its target proteins, such as
254 de the ability of cells to properly fold and posttranslationally modify secretory and transmembrane p
255 plexes are key gene regulatory factors which posttranslationally modify the histone component of chro
256 elial cell surface plasminogen activation by posttranslationally modifying annexin A2, the coreceptor
257 lpha (ERalpha) can modulate gene activity by posttranslationally modifying histone tails at target pr
260 ein Isu, the abundance of which is regulated posttranslationally on disruption of the cluster biogene
262 oxidation, in which methionine residues are posttranslationally oxidized to methionine sulfoxide.
263 l ubiquitin-like modifier (SUMO) to proteins posttranslationally, plays an important role in regulati
265 ain their ability to produce full-length and posttranslationally processed envelope proteins in cell
266 tructural glycoproteins, Gn and Gc, that are posttranslationally processed from precursors PreGn and
267 proteins were either decreased in amount or posttranslationally processed in a manner different from
269 enome RNA into polyproteins that are co- and posttranslationally processed into intermediate and matu
270 , and the majority of this protein is likely posttranslationally processed into the 65-kD protein PSR
272 V) genome encodes a capsid precursor that is posttranslationally processed to release the mature caps
275 GT1 acts as an ER quality control sensor by posttranslationally reglucosylating glycans on slow-fold
276 e a similar C-terminal degradation system to posttranslationally regulate the activity of DesA3 and o
278 e yeast Smf1p Nramp manganese transporter is posttranslationally regulated by environmental manganese
280 re are dozens of cysteine proteases that are posttranslationally regulated by processing, environment
281 yzes the reduction of oxygen to water and is posttranslationally regulated by redox mechanisms and 2-
282 20 histone methyltransferase PR-Set7/Set8 is posttranslationally regulated by the PCNA-dependent CRL4
285 on-mediated p27(Kip1) and p21 increases were posttranslationally regulated via the down-regulation of
287 n convertase subtilisin/kexin type 9 (PCSK9) posttranslationally regulates hepatic low-density lipopr
288 tion regulates the proteolysis of PALs, thus posttranslationally regulating phenylpropanoid metabolis
294 ed proteins must be recognized and delivered posttranslationally to the endoplasmic reticulum or mito
295 The ribosomal protein L11 in bacteria is posttranslationally trimethylated at multiple amino acid
296 erved in tRNA that are believed to be formed posttranslationally via a biosynthetic intermediate that
297 o, small secretory proteins can enter the ER posttranslationally via a transient cytosolic intermedia
298 The Sec62-dependent translocation occurs posttranslationally via the Sec61 translocon and require
299 L2 are tail-anchored proteins that associate posttranslationally with membranes and likely require sp
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