ライフサイエンスコーパス: postzygotic

1 We conclude that CLOVES is caused by postzygotic activating mutations in PIK3CA.

2 ndencies that govern a cell's entry into the postzygotic and exconjugant developmental programs.

3 kage disequilibrium between loci involved in postzygotic and premating isolation must often be built

4 relates to its effect on the pathway between postzygotic and prezygotic isolation.

5 mating may play a dual role as an important postzygotic as well as a premating reproductive barrier

6 two members, AGL62 and AGL90, attenuated the postzygotic barrier between A. thaliana and A. arenosa.

7 sting studies confirm the polygenic basis of postzygotic barriers and demonstrate the utility of gene

8 Little is known about how pre- and postzygotic barriers will affect the prospects of "admix

9 rns are due to assortative mating and strong postzygotic barriers, rather than recent population hist

10 e revealed an unexpectedly high incidence of postzygotic chromosomal abnormalities, which might arise

11 essian fly sex determination system in which postzygotic chromosome elimination is used to establish

12 constructed cell lineages for the first five postzygotic cleavages and calculated a mutation rate of

13 ibitor actinomycin D disrupts many events of postzygotic conjugation (cycloheximide causes indistingu

14 Igf2 and H19 and of other imprinted genes to postzygotic de novo methylation may be the molecular bas

15 The decision to proceed with postzygotic development is governed by a developmental c

16 established in oogenesis, maintained during postzygotic development on the maternal allele, and eras

17 sequences of events: prezygotic development, postzygotic development, and exconjugant development.

18 Early treatment causes a block of all postzygotic development, suggesting a transcription requ

19 re to replicate DNA, and failure to initiate postzygotic development.

20 ts to pass a checkpoint, allowing entry into postzygotic development.

21 dably perpetuates an epigenetic state during postzygotic development.

22 understood function, we identified imprinted postzygotic DNA methylation maintenance, likely by direc

23 Two rounds of postzygotic DNA replication occur normally in progeny of

24 Expansion has been suggested to be a postzygotic event with the germline protected.

25 arose during MI, 29% during MII and 16% were postzygotic events; a further 7% were meiotic but could

26 may already exist in the maternal oocyte, or postzygotic expansion, if it occurs, arises quite early

27 st vascular anomalies with overgrowth harbor postzygotic gain-of-function mutations in oncogenes.

28 we observed are the result of inhibition of postzygotic gene expression, presumably in anlagen.

29 onditions, and considers the role of somatic postzygotic genetic lesions in brain maldevelopment.

30 lated species Arabidopsis arenosa results in postzygotic hybrid incompatibility, manifested as seed d

31 rent ploidy levels are separated by a strong postzygotic hybridization barrier that is established in

32 pment, we identify three PEGs that establish postzygotic hybridization barriers in the endosperm, rev

33 Recent studies showed remarkable pre- and postzygotic incompatibilities between sympatric colour m

34 number of genes involved in these "intrinsic postzygotic incompatibilities" should increase faster th

35 g allopatry, premating behavioral isolation, postzygotic inviability and Wolbachia-induced cytoplasmi

36 oward understanding the genetic basis of the postzygotic isolating mechanisms of hybrid sterility and

37 oward understanding the genetic basis of the postzygotic isolating mechanisms of hybrid sterility and

38 Hybrid sterility is one of the earliest postzygotic isolating mechanisms to evolve between two r

39 ogress in understanding the genetic basis of postzygotic isolating mechanisms, little is known about

40 icient amount of time for the development of postzygotic isolation among the three species that hybri

41 First, postzygotic isolation appears to involve a modest number

42 epistatic incompatibilities contributing to postzygotic isolation behave as X-linked partial recessi

43 We analyzed the genetic basis of postzygotic isolation between the Bogota and USA subspec

44 We go on to study how postzygotic isolation caused by epistatic incompatibilit

45 This incomplete postzygotic isolation could allow ongoing interploid gen

46 Sex linkage of genes involved in postzygotic isolation generally increases the strength o

47 fying and characterizing factors involved in postzygotic isolation in Drosophila has remained slow, m

48 nothing is known about the genetic basis of postzygotic isolation in the genus.

49 we show that the number of genes involved in postzygotic isolation increases at least as fast as the

50 Whereas postzygotic isolation is now complete because of sterili

51 have sex chromosomes evolve lower levels of postzygotic isolation than taxa with sex chromosomes, at

52 Postzygotic isolation was calculated for each cross as t

53 Postzygotic isolation was significantly lower in tetrapl

54 Postzygotic isolation was weaker among higher order poly

55 arge X-effect, describe the genetic basis of postzygotic isolation, and have led to the realization t

56 Additional postzygotic isolation, caused, for example, by either ep

57 ntifying genes and mutations responsible for postzygotic isolation, little is known about the genetic

58 Unlike the genetic components of postzygotic isolation, the loci for prezygotic isolation

59 eproductive isolation--especially intrinsic, postzygotic isolation--does not seem to be the rate-limi

60 e character displacement may have reinforced postzygotic isolation.

61 ontribute to a faster evolution of intrinsic postzygotic isolation.

62 x chromosomes for the evolution of intrinsic postzygotic isolation.

63 solation also appears to result in increased postzygotic isolation.

64 r genomic forces that drive the evolution of postzygotic isolation.

65 rangements appear to contribute to intrinsic postzygotic isolation.

66 ive in the evolution of the genes that cause postzygotic isolation.

67 n reflect the recessivity of alleles causing postzygotic isolation.

68 ule and the large effect of X chromosomes on postzygotic isolation.

69 ic) groups meet after having evolved partial postzygotic isolation; they are selected to evolve or en

70 thaliana genome that affect the frequency of postzygotic lethality and the phenotypes of surviving se

71 Postzygotic lethality of interspecies hybrids can result

72 tween prezygotic nuptial gifts and exclusive postzygotic male care and support the hypothesis that, i

73 ickle cell trait has mild SCD resulting from postzygotic mitotic recombination leading to UPD.

74 stage (meiosis I [MI], meiosis II [MII], or postzygotic mitotic) of the chromosomal error.

75 Sex ratio distortion is independent of postzygotic mortality, and is not associated with an obv

76 blood, indicating that these conditions are postzygotic mosaic disorders.

77 Postzygotic mosaic mutations (PMMs) have been implicated

78 ypic and genetic heterogeneity combined with postzygotic mosaicism.

79 ure by segmental Darier's disease induced by postzygotic mosaicism.

80 ve recently been shown to be due to a single postzygotic mutation in NRAS [neuroblastoma RAS viral (v

81 We hypothesized that a single postzygotic mutation in NRAS could be responsible for mu

82 The occurrence of postzygotic mutation in the early mouse embryo suggests

83 We systematically analyzed postzygotic mutations (PZMs) in whole-exome sequences fr

84 1 unrelated families with MPPH and 15 mostly postzygotic mutations in PIK3CA in 23 individuals with M

85 We identified de novo germline or postzygotic mutations in three core components of the ph

86 These results suggest that single postzygotic NRAS mutations are responsible for multiple

87 r exchange, pronuclear fusion, and anchoring postzygotic nuclear division products to the posterior c

88 cnj9 eliminates the second postzygotic nuclear division, and subsequently, new macr

89 rd prezygotic nuclear division and the first postzygotic nuclear division.

90 ly neoplasm frequently associated with early postzygotic occurrence of this genomic alteration.

91 male care of offspring is the rarest form of postzygotic parental care among animals and has arisen i

92 To determine whether postzygotic rejection of self-fertilized ovules is due t

93 inviable seed formation, revealing a strong postzygotic reproductive barrier separating these two sp

94 le insights into the nature and evolution of postzygotic reproductive barriers in diverged species.

95 s of experimental hybrids indicate that most postzygotic reproductive barriers in plants are polygeni

96 of the heterogametic sex is one of the first postzygotic reproductive barriers to evolve during speci

97 Much evidence has shown that postzygotic reproductive isolation (hybrid inviability o

98 This study evaluates postzygotic reproductive isolation among three cytotypes

99 Polyploidy confers postzygotic reproductive isolation and is thought to dri

100 important implications for the evolution of postzygotic reproductive isolation and speciation.

101 This form of postzygotic reproductive isolation appears to be highly

102 tural selection might drive the evolution of postzygotic reproductive isolation even when allopatric

103 Postzygotic reproductive isolation evolves when hybrid i

104 ly-acting and potentially widespread form of postzygotic reproductive isolation is largely unknown.

105 The Dobzhansky-Muller model posits that postzygotic reproductive isolation results from the evol

106 Organisms that quickly evolve prezygotic or postzygotic reproductive isolation should have faster ra

107 obzhansky-Muller model posits that intrinsic postzygotic reproductive isolation--the sterility or let

108 characterize the mechanisms and strength of postzygotic reproductive isolation.

109 of genes contributing to the maintenance of postzygotic reproductive isolation.

110 that has been implicated in the evolution of postzygotic reproductive isolation.

111 gene expression play important roles in the postzygotic seed abortion in interspecific hybrids or ne

112 The mechanism behind this postzygotic seed abortion is poorly understood.

113 stitution is more likely to be the result of postzygotic selection against other unbalanced karyotype

114 Postzygotic somatic mutations activating the phosphatidy

115 such as Arabidopsis thaliana and A. arenosa, postzygotic species barriers often affect seed abortion,

116 thal and zygotic-rescue activities to gain a postzygotic survival advantage.