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1 hich other triggers for drug use become more potent.
2 erved with lorcaserin, a 5-HT2C agonist with potent 5-HT2B and 5-HT2A agonist activities, which is ap
3 oxic capacity, 4-1BB ligation demonstrates a potent ability to restore effector functions.
4 we show that the XPC DNA repair complex is a potent accelerator of global and locus-specific DNA deme
5 ing the pentafluorosulfanyl (SF5) group as a potent acceptor has been synthesized.
6                                   NKG2D is a potent activating immunoreceptor that has emerged as an
7 ound binding to the Sirt6 catalytic core and potent activation of Sirt6-dependent deacetylation of pe
8 e identified tacrolimus (FK-506) as the most potent activator of ALK1 signaling in BMP9-challenged C2
9 ppaB independently of BST2, VP40 is the more potent activator.
10 ven that TGF-beta1 and myocardin (MYOCD) are potent activators for VSMC differentiation, we screened
11         The resultant lead compounds possess potent activity against a multidrug resistant strain of
12 the new complexes are phototoxic and display potent activity against chemotherapeutically resistant c
13 ine receptors (A1, A2a, and A3) as well as a potent activity at a kinase, FLT3.
14 ailable, with no overt signs of toxicity and potent activity in both murine xenograft and patient-der
15                      These data suggest that potent adjuvants, such as cationic adjuvant formulation
16  to carrier proteins and/or formulation with potent adjuvants.
17                  Thus, GRA6Nt is a novel and potent Ag to activate CD8(+) T cells capable of removing
18                           Moreover, they are potent against endogenous AC in intact melanoma cells.
19 h IC50 values of less than 20 nM, is <100 nM potent against JAK2 and HDAC11, and is selective for the
20  extent than salinomycin, an established CSC-potent agent.
21 ive significant clinical benefit from a more potent ALK inhibitor after failure of crizotinib, and es
22       The S aureus-derived protein SplD is a potent allergen of S aureus and induces a TH2-biased inf
23 te, unique specificity-enhancing factor, and potent allosteric activator.
24                              SzV-1287 exerts potent analgesic and anti-inflammatory actions in chroni
25 onstrained derivative 36 emerged as the most potent analogue with a KD of 76 nM against BioA and a mi
26 its D-enantiomer, D-RR4, emerged as the most potent analogues with a more than 32-fold improvement in
27 es in identification of donors with the most potent and broad anti-HIV serum neutralizing responses w
28  elicit distinct antibody specificities with potent and broad neutralizing activity against all seven
29                                       Highly potent and broadly neutralizing anti-HIV-1 antibodies (b
30  compound 27 (DNS-8254), was identified as a potent and highly selective PDE2a enzyme inhibitor with
31 uin rearranging ligands (SirReals) as highly potent and isotype-selective Sirt2 inhibitors with thali
32 oparticle (NP; PC7A), in human PBMCs induces potent and long-acting antiretroviral response against s
33                                         More potent and longer antiplatelet therapy may be beneficial
34     Oligomeric proanthocyanidins (OPACs) are potent and renewable natural bioactives possible to be r
35 on led to identification of compound 25 as a potent and selective A2A adenosine receptor (A2AAdoR) an
36 ibitors, these quinolizidines revealed to be potent and selective alpha-glucosidase inhibitors.
37               Lead compounds discovered have potent and selective antiproliferative activities, and m
38  perspectives in the development of new more potent and selective arsenical drugs against solid tumor
39 sing SBDD culminated in the discovery of the potent and selective Brr2 inhibitor 9 with helicase inhi
40                      Here, we present highly potent and selective fluorescent inhibitors that we show
41 2-yl)pyrimidin-2-amine derivatives as highly potent and selective inhibitors of CDK4 and CDK6.
42 as found to be sufficient to explain Pre1a's potent and selective inhibitory effect on the fast inact
43 4A-activating C-DIM compounds may serve as a potent and selective means to enhance memory and synapti
44             5-Cyano compounds are especially potent and selective rat and human nNOS inhibitors.
45  against pathogens that can also result in a potent and sometimes pathological inflammatory response.
46 , our study supports that 38u might act as a potent and specific AEP inhibitor useful for cancer trea
47               In this study we report that a potent and specific small molecule antagonist of the CCR
48 n, butanol also enhanced fusion but was less potent, and low doses of methanol mildly inhibited fusio
49  forward in the search of chemically simple, potent, and selective antagonists for the hA3AR, and exe
50 report for the first time a series of novel, potent, and selective inhibitors of IKKalpha.
51 r cabazitaxel (n = 22); 44.4% received prior potent androgen receptor-targeted therapy.
52 , HDAC2 represses thrombospondin-1 (TSP1), a potent angiogenesis inhibitor, through epigenetic regula
53                 The activation of Akt by the potent angiogenic factor VEGF-A does not strongly stabil
54 at drugs designed to target this site may be potent anti-cancer agents.
55 pholide (ANDRO), a botanical compound, has a potent anti-inflammatory activity due to its ability to
56 s corticosteroids) are steroid hormones with potent anti-inflammatory and immune modulatory profiles.
57 cialized proresolving mediator (SPM) hosting potent anti-inflammatory and proresolving properties wit
58           They also suggest that novel, more potent anti-Wolbachia drugs under development may be cap
59       We identified and confirmed the highly potent antiandrogen 4-methyl-7-diethylaminocoumarin (C47
60 tion is showcased by the construction of the potent antibacterial marine natural product bromophycoic
61  polyketide/fatty acid backbones and exhibit potent antibiotic activity against methicillin-resistant
62  a global threat as the clinically available potent antibiotic drugs are becoming exceedingly scarce.
63 winian process in which B lymphocytes evolve potent antibodies to encountered antigens and generate i
64 ne therapy (ET) with trastuzumab or with the potent antibody-cytotoxic, anti-HER2 compound trastuzuma
65 romising combinations of approved drugs with potent anticancer activity for further mechanistic study
66 of hydroxy fatty acids (FAHFAs), lipids with potent antidiabetic and anti-inflammatory activities, in
67 n (4-hydroxy-N-desmethyltamoxifen), the most potent antiestrogenic metabolite, are reduced in women w
68                       The cytokine IL-10 has potent antifibrotic effects in models of adult fibrosis,
69              Notably, JNK inhibitors exerted potent antifungal therapeutic effects in both mouse and
70 e pro-inflammatory cytokines and act as more potent antigen presenting cells.
71 o allergic disease is mediated through their potent antigenicity.
72                         Aged garlic has more potent antiglycation and antioxidant properties compared
73            We and others previously reported potent antileukemia efficacy of CD123-redirected chimeri
74 -alkynyl-1,2,3-triazole family that exhibits potent antileukemic effects on several hematologic malig
75 to strong membrane disruptive capability and potent antimicrobial activity.
76 oride anion to generate hypochlorous acid, a potent antimicrobial agent.
77 vancomycin disaccharide to provide even more potent antimicrobial agents [VRE minimum inhibitory conc
78 isting mainly of monoterpenes, including the potent antimicrobial and insecticidal monoterpene 3-care
79 stems, chemical defence systems comprised of potent antimicrobial compounds released by prospective h
80 ared from patients and healthy donors confer potent antimyeloma reactivity.
81 .11) mg GAEg(-1) respectively, and exhibited potent antioxidant activity (from 0.28+/-0.01 to 5.34+/-
82  Our results demonstrate that 5-HT acts as a potent antioxidant and binds with a superior affinity to
83                                       It's a potent antioxidant and can also act as a pro-oxidant tha
84 odocytes and that NAC (N-acetyl-cysteine), a potent antioxidant, significantly eliminated the excessi
85 ed to compare clopidogrel with ticagrelor, a potent antiplatelet agent, in patients with peripheral a
86 ibitors with increased PACE4 selectivity and potent antiproliferative effects.
87  have resulted in compounds with moderate to potent antitubercular activity and improved physicochemi
88 d inspired the discovery of a novel class of potent antitubercular agents that unexpectedly possessed
89 apsigargin, a cytotoxic natural product with potent antitumor activity.
90 agellin derivatives, have been shown to have potent antitumor and metastasis-suppressive effects in m
91  model of SHH-subtype medulloblastoma exerts potent antitumor effects.
92 V-1 integrase strand transfer inhibitor with potent antiviral activity and a long half-life when admi
93  Taken together, these data suggest that the potent antiviral capacity of some HIV-specific CD8(+) T
94 standing of the mode of action of the highly potent antiviral drugs that are targeted to NS5A.
95  of arenavirus nucleoproteins and uncovers a potent antiviral host protein that is neutralized during
96 tive consequences of quantum mechanics, with potent applications in cryptography and computing.
97 nd aroma extract dilution analysis, the most potent aroma components include: dipropyl disulfide, S-p
98 at the African ZIKV isolate (MR-766) is more potent at causing brain damage and postnatal lethality t
99  several models of inflammation yet was less potent at inhibiting chemotaxis in vitro with an IC50 of
100 e now show that ANI-7 is up to 263-fold more potent at inhibiting the growth of breast cancer cell li
101 show that HLA-B*14-EL9 is substantially more potent at inhibiting viral replication than HLA-B*14-DA9
102           Indirubins have been identified as potent ATP-competitive protein kinase inhibitors.
103 inks innate and adaptive immunity, promoting potent B cell responses.
104 phically intractable fragment hits into more potent binders.
105 for a variety of GPCRs with a propensity for potent binding across therapeutically relevant adenosine
106  natural and synthetic compounds, often with potent biological activity.
107 l design parameters for the creation of more potent biological delivery agents for research and biome
108 ndent growth rates of two algae that produce potent biotoxins, Alexandrium fundyense and Dinophysis a
109  and accelerate the events that give rise to potent bNAb in vivo.
110                             Some of the most potent bnAbs target a quaternary epitope at the apex of
111 30 and rLmI/h30 vaccines were generally more potent booster vaccines than r30 with an adjuvant and a
112 to the identification of a new generation of potent broadly neutralizing antibodies (bNAbs).
113 pproach we discovered a highly selective and potent BTK kinase inhibitor (CHMFL-BTK-11) which exerted
114 ower trypsin inhibitor-1 (SFTI-1) produced a potent cathepsin G inhibitor (Ki = 0.89 nM).
115 rapy in that it facilitates the emergence of potent CD8(+) T-cell immunity able to durably suppress v
116 fter prolonged exposure to the selective and potent CDK4/6 inhibitor LY2835219, clones emerged and se
117 mportant attribute to consider for obtaining potent cell-based inhibition of this cancer metabolism t
118                      Concurrent induction of potent cellular and humoral immune responses was also ac
119                  Cisplatin is a particularly potent chemotherapeutic agent, but its use to treat GBM
120 ive neurobiological mechanism underlying the potent combination of psychotherapy and somatic stimulat
121                                     The most potent compound of the present series, sodium 1-amino-4-
122                               The three most potent compounds 1g-i showed IC50 values in the low muM
123 we here identify arylmethylamino steroids as potent compounds and characterize more than 60 derivativ
124      The previously identified selective and potent CYP11B1 inhibitor 5-((5-methylpyridin-3-yl)methyl
125                                  It exhibits potent cytostatic properties (mean of 50% growth inhibit
126 t that less polar analogues of curcumin have potent cytotoxicity in vitro.
127 abdane diterpenoids that were reported to be potent cytotoxins.
128 s of ternary complex formation and were more potent degraders than tetrahydroquinoline compounds, whi
129 uggest that hepsin, like matriptase, induces potent destruction of the extracellular matrix whilst di
130 ting tools may allow rapid identification of potent dietary inhibitors.
131 colibactins) are unsaturated imines that are potent DNA damaging agents, thereby confirming an earlie
132  3'-telomeric overhang of telomeres, elicits potent DNA-damage responses in melanoma cells; however,
133 aneous administration of ALN-GO1 resulted in potent, dose-dependent, and durable silencing of the mRN
134 r and BTB domain-containing 7b (Zbtb7b) as a potent driver of brown fat development and thermogenesis
135 C5a, which, through its receptor C5aR1, is a potent driver of inflammation.
136 roducts obtained and its use in synthesis of potent drug molecules.
137             Lack of availability of durable, potent drugs in child-friendly formulations in LMICs and
138     Consequently, Lp/OVA/StII induced a more potent effector function, as shown by CTLs, in vivo assa
139 lls in the tumor microenvironment that exert potent effects on cancer metastasis.
140 mbined SFK/FAK inhibition exhibited the most potent effects on growth inhibition, induction of apopto
141                         Serum bilirubin is a potent endogenous antioxidant and has been identified as
142 ne of the challenges these species face is a potent environmental source of DNA double-strand breaks,
143 esulted in the discovery of some of the most potent epothilones reported to date.
144  immunogenic, but it is expected that a more potent formulation will be required to establish antibod
145                     The resulting stable and potent FPR2-selective antagonists (i.e., RhB-(Lys-betaNp
146 onin containing fraction-4 (F4) was the most potent fraction based on its ability to inhibit ROS prod
147        Herein we describe the discovery of a potent FXIa clinical candidate, 55 (FXIa Ki = 0.7 nM), w
148 starting from the structural similarity of a potent G4 ligand previously discovered by our group and
149           Moreover, we observed a remarkably potent gating mechanism when the animal was standing on
150 reversible production and consumption of the potent greenhouse gas methane.
151 nitrification represent major sources of the potent greenhouse gas nitrous oxide (N2O).
152 ocess that is a major source and sink of the potent greenhouse gas nitrous oxide.
153                The utilization of methane, a potent greenhouse gas, is an important component of loca
154 lobal source of atmospheric methane (CH4), a potent greenhouse gas.
155 ologous transactivation domains can act as a potent guide RNA sequence-directed inducer or repressor
156                                   GS-5745, a potent, highly selective humanized monoclonal antibody i
157 ich we obtained X-ray structures of the most potent hit (compound 19, IC50 = 2.9 muM) in complex with
158                                          The potent HN analogue HNG protects from stressor-induced ce
159 es containing the MERS-CoV S1 protein induce potent immune responses against MERS-CoV and RABV.
160 lent safety profile and property of inducing potent immune responses against recombinant (r) antigens
161                 CD8(+) T lymphocytes mediate potent immune responses against tumor, but the role of h
162 s vaccination strategies to elicit broad and potent immune responses based on the immunomodulatory pr
163 ent pathogen Streptococcus pyogenes secretes potent immunomodulatory proteins known as superantigens
164      Among them, ginsenoside Ro was the most potent in inhibiting embryonic implantation within non-c
165 ession of the wild-type PDGFRA was even more potent in promoting transformation than the mutant PDGFR
166                  Both compounds were equally potent in stimulating cAMP signaling in the mouse hippoc
167               Although macrophages were more potent in uptaking tumor DNA, increase of DNA sensing by
168 ocally acting SGLT1 inhibitor that is highly potent in vitro and delays intestinal glucose absorption
169 er of the vitamin E family of compounds with potent in vitro anti-cancer properties, is limited by it
170          The more recent revelation of their potent in vitro antiplasmodial activity sparked new ende
171 d to have limited brain penetrance, elicited potent in vitro CB1R antagonist activities and iNOS inhi
172  proliferation of cSCC cells and resulted in potent inhibition of extracellular signal-regulated kina
173                    All four compounds showed potent inhibition of HDAC1-3 as well as significant inhi
174 he flavone A-ring backbone are essential for potent inhibition of LasR/RhlR.
175                     The new IASs 8-37 showed potent inhibition of the HIV-1 WT NL4-3 strain and of th
176 ed compared with soluble protein, leading to potent inhibition of wound closure following PMN-MP bind
177 l acetamide, has been identified as a novel, potent inhibitor against human 11beta-hydroxysteroid deh
178  exemplifies as a cautionary tale how a more potent inhibitor does not necessarily generate more pote
179 action assay, was less cytotoxic, and a more potent inhibitor of alpha-smooth muscle actin protein ex
180 inhibitory assays demonstrated that it was a potent inhibitor of human cathepsins B, K, and L ( Ki =
181 ive E2f-mediated transactivation of Socs3, a potent inhibitor of Jak2 signaling, in cycling HSCs.
182 eoxyriboside triphosphate, in vivo creates a potent inhibitor of several human DNA polymerases that c
183  Here, we describe the discovery of the most potent inhibitor of sirtuin 5 (SIRT5) reported to date.
184             These results show that VPA is a potent inhibitor of STAT3 phosphorylation and demonstrat
185                                      It is a potent inhibitor of the mRNA decapping scavenger enzyme
186 ng cells (IC50 = 230 nM), providing the most potent inhibitor of the sonic hedgehog/patched interacti
187                     Cediranib (AZD2171) is a potent inhibitor of tyrosine kinase activity associated
188 e SET8-NQO1/TRXR1 axis with its specific and potent inhibitors could lead to promising host-directed
189 tetrazole-containing derivatives were highly potent inhibitors in both assays, with complete inhibiti
190  In particular, compounds 13 and 14 are very potent inhibitors in that they demonstrated the lowest I
191 er exhibit poor amyloid formation and act as potent inhibitors in trans of simple polyQ peptide aggre
192 tial, we targeted our efforts at identifying potent inhibitors of FXIa with a focus on discovering an
193  This work identifies TGF-beta1 and BMP-2 as potent inhibitors of IL-34 expression in RA synovial fib
194 in use in humans, digoxin and digitoxin, are potent inhibitors of multiple adenovirus species.
195 ludes lipid substrates for enzymatic assays, potent inhibitors, and chemical probes to detect, track,
196                               Cangrelor is a potent intravenous adenosine diphosphate-receptor antago
197 G505 SOSIP, have improved the elicitation of potent isolate-specific antibody responses in rabbits an
198 orum-sensing (QS) apparatus have a rapid and potent killing phenotype following microinjection into a
199 discharge but introduce larger quantities of potent LMW-DON into coastal systems.
200 -targeted histone deacetylase inhibitors and potent LRAs.
201 s study, we demonstrate that GA101 is a more potent mediator of trogocytosis than RTX in vitro in bot
202             CLIPA14 kd mosquitoes elicited a potent melanization response against Plasmodium berghei
203 rain penetrating PDE1B enzyme inhibitor with potent memory-enhancing effects in a rat model of object
204                                              Potent methylation is dependent on the multimerization o
205 naturally in peppermint oil, known for their potent, mint-like olfactory properties.
206 on will enable the structure-based design of potent modulators of these clinically relevant enzymes.
207                                      MDMA, a potent monoamine-releaser with particularly pronounced s
208 F-GCN4t was also shown to bind D25, a highly potent monoclonal antibody specific for the pre-F confor
209                           N-Nitrosamines are potent mutagens and carcinogens that can be formed durin
210          In previous work, we have generated potent MV fusion inhibitors by dimerizing the F-derived
211 or family 2), demonstrates that it possesses potent NAD(P)(+) hydrolase activity.
212  environmental health concerns since it is a potent neurotoxicant.
213                                              Potent neurotoxins like tetrodotoxin (TTX) and saxitoxin
214  Methylmercury (MeHg(+) ) is one of the most potent neurotoxins, which damages the brain and nervous
215 active breadth for sera identified as having potent neutralization activity based on initial screenin
216  spread in fibroblasts, including those with potent neutralizing activity against fibroblast entry, w
217                  Previously, we identified a potent neutralizing antitoxin against BoNT/A1 termed ciA
218 ty relationships (SAR) and identification of potent new monobactam antibiotics.
219 tes, and Proteobacteria phyla, we found that potent Nod-like receptor-stimulating bacteria in the upp
220  The design and synthesis of a new series of potent non-prostanoid IP receptor agonists that showed o
221 itis B patients under long-term therapy with potent nucleos(t)ide analogues is currently unclear.
222 rotein at the Jkappa site (RBP-J) protein, a potent OC inhibitor.
223  result in altered on-target sites and novel potent off-target sites, which can predispose patients t
224 munocytokines that are up to 1,000-fold more potent on target cells, allowing specific signaling in s
225      Administration of bictegravir, a novel, potent, once-daily INSTI designed to improve on existing
226 ly screened to obtain the most efficient and potent ones.
227 ane proteins SUN1/UNC84A and SUN2/UNC84B are potent or modest inhibitors of HIV-1 infection, respecti
228 fragment-derived lead resulting in AT-IAP, a potent, orally bioavailable, dual antagonist of XIAP and
229                                              Potent P2Y12 inhibitors significantly reduced the risk o
230 with inhaled or topical delivery resulted in potent pan-JAK inhibitor 2 (PF-06263276), which was adva
231 y of PDE2A inhibition, we sought to identify potent PDE2A inhibitors with improved brain penetration
232                          Polytheonamides are potent peptide cytotoxins produced by uncultivated bacte
233                               Pepstatin is a potent peptidyl inhibitor of various malarial aspartic p
234  whereas Pt-G4K(+)B hydrogels exhibited more potent photocytotoxicity (IC50 3 muM, blue light) with a
235 ation of all-trans retinoic acid (ATRA) as a potent Pin1 inhibitor provides a promising candidate for
236                                    GW9662, a potent PPARgamma antagonist, blocked the antileukemic ef
237 of the MVM-induced DDR is establishment of a potent premitotic block.
238 d incorporation assays: TGFbeta1 delivered a potent pro-fibrotic stimulus, which was reduced by TGFbe
239 inhibitor does not necessarily generate more potent PROTACs and underscores the key roles played by t
240 ed that these viral vectors can mediate more potent protection against influenza virus infection in a
241 atase 1 regulatory subunit 1A (PPP1R1A) is a potent protein phosphatase 1 (PP1) inhibitor; however, i
242 e results suggest a novel role for EMCN as a potent regulator of angiogenesis and point to its potent
243 mation, our data demonstrate that IL-27 is a potent regulator of ROS induction and may be a novel the
244 and bryostatin-1 could thus be considered as potent regulators of BBB permeability and inflammation t
245 l, strains carrying the pocR gene locus were potent reuterin producers, with L. reuteri 17938 inhibit
246         Serine hydrolases are susceptible to potent reversible inhibition by boronic acids.
247 IL-7-immunized mice promptly produced a more potent secondary anti-RABV neutralizing antibody respons
248  of rapid ecological change, one of the most potent selective forces, sexual selection, remains curio
249                              Seladelpar is a potent, selective agonist for the peroxisome proliferato
250 e-based drug design has resulted in a highly potent, selective, brain penetrant compound 71 (PF-05085
251 n resulted in rapid elicitation of broad and potent serum antibody responses in all four cows.
252 ed ascarosides, which include several highly potent signals in intra and interspecies communication a
253 pore-forming protein Perfringolysin O (PFO), potent silencing was achieved in vitro with no detectabl
254                        Our results establish potent Sirt6 activation with small molecules and provide
255  these data demonstrate that 6E11 is a novel potent small molecular inhibitor of RIPK1-driven necropt
256 oji berries therefore might represent a more potent source of macular pigments than green leafy veget
257 P1B inhibitor trodusquemine (MSI-1436), is a potent, specific, and orally bioavailable inhibitor of P
258 cutaneous leishmaniasis, identifying several potent structures that exhibited EC50 values of <100 nM.
259 nyl))I](+) (where p-cym=para-cymene) exhibit potent sub-micromolar antiproliferative activity towards
260       The resulting data clearly indicated a potent suppression of tumor necrosis factor alpha releas
261 0 overexpression, we identified miR-100 as a potent suppressor of endothelial adhesion molecule expre
262 which encodes an H3K36 methyltransferase, as potent suppressors of morc-1(-) and nuclear RNAi mutant
263 atabase indicates that the structure of most potent sweeteners combines a hydrophobic scaffold functi
264 bination and PARP-mediated DNA repair yields potent synthetic lethality in triple-negative breast tum
265                We show this strategy elicits potent T cell responses toward highly conserved internal
266  used viral vectors and is known to generate potent T cell responses.
267 s scFvFITC:sTRAIL and scFvFITC:sFasL induced potent target antigen-restricted apoptosis in a panel of
268      These results suggest that REV-ERB is a potent target for the treatment of DMD.
269 lin-36-[L28C(30kDa-PEG)] is 10,000-fold less potent than apelin-36 at activating the APJ receptor but
270 rogenic effects to BPA and that BPAF is more potent than BPA, further highlighting health concerns re
271 on led to compound 28, which was 4-fold more potent than its parent 3.
272 system, Proxison is orders of magnitude more potent than natural flavonoids at protecting neural cell
273  inhibition of Notch signaling that was more potent than pharmacologic blockage of Notch activation v
274 ll receptor coregulatory molecule GITR exert potent therapeutic activities in preclinical tumor model
275 cles such as cyclosporine are among the most potent therapeutics identified to date, but there is cur
276 ase TbtI involved in the biosynthesis of the potent thiopeptide antibiotic thiomuracin.
277 nflammatory and proresolving properties with potent tissue regenerative actions.
278 all changes in arterial CO2 are particularly potent to change CBF (1 mmHg variation in arterial CO2 c
279  Thus, R. typhi(GFPuv) bacteria are a novel, potent tool to study infection with the pathogen in vitr
280                           Localised adjuvant potent topical corticosteroids (<30 g per week) were per
281 ut the mechanism of trafficking for the more potent toxin STx2 is unclear.
282      Botulinum neurotoxins (BoNTs), the most potent toxins known, are potential bioterrorism agents.
283  of the UPR, cleaves Xbp1 mRNA to generate a potent transcription factor adaptive toward ER stress.
284                                 XEN-D0501 (a potent TRPV1 antagonist) was compared with SB-705498 in
285 zine moiety for the development of novel and potent tubulin polymerization inhibitors.
286      We uncover a role in senescence for the potent tumor suppressor and ATM substrate USP28.
287 el reprogramming factor for melanocytes with potent tumor transformation potential.
288 , Ace-DEX MP-encapsulated cGAMP represents a potent vaccine adjuvant of humoral and cellular immunity
289       Isolated or synthetic lipopeptides are potent vaccine adjuvants, interacting with cell surface
290 Justicidin B is structurally similar to more potent vacuolar-type H(+)-ATPase inhibitors, which all i
291                     Endothelin-2 (EDN2) is a potent vasoconstrictor that is transiently produced prio
292 c oxide synthase (eNOS), which generates the potent vasodilator nitric oxide (NO), is decreased.
293 er adeno-associated virus (AAV) vectors as a potent vector for the cochlear cell targets.
294  (APOBEC) 3 proteins have been identified as potent viral DNA mutators and have broad antiviral activ
295 + EP promoted strong IFN-gamma responses and potent viral inhibition.
296 cretory antigenic target (ESAT-6) is a known potent virulence and antigenic determinant.
297                         Compound 1f was most potent with a minimal inhibitory concentration (MIC) of
298          CCG-222740 was also five times more potent, with an IC50 of 5 muM, in a fibroblast-mediated
299 man cholangiocyte cell line and demonstrated potent wound healing in mice.
300 icatumtoxin B led to the discovery of highly potent, yet simpler analogues of the molecule.

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