ライフサイエンスコーパス: potentially

1 hat the alpha-hydroxyketone rearrangement is potentially a conserved biosynthetic reaction in this mo

2 Focusing intervention efforts on LTACHs is potentially a highly efficient strategy for reducing CRE

3 Interneurons are potentially able to function on both a highly localized,

4 ng with a TMA also had aHUS risk haplotypes, potentially accounting for the genetic pleiotropy.

5 tein stability offers a fast, economical and potentially accurate alternative to laboratory mutagenes

6 io-economic disparities in the US population potentially achievable from 2015 to 2030 with specific d

7 tic niches, express nitrous oxide reductase, potentially acting as a global sink for the greenhouse g

8 nd-atmosphere CH4 emissions for this region, potentially acting as a positive feedback to climate war

9 Most individuals had at least one potentially actionable alteration (94.7%), with the medi

10 lteration (94.7%), with the median number of potentially actionable alterations per patient being 2 (

11 Glioblastoma (GBM) tumors exhibit potentially actionable genetic alterations against which

12 ns and cross-reactive antibodies (Abs) could potentially affect ZIKV pathogenesis.

13 teria and their microinvertebrate consumers, potentially affecting energy and nutrient transfer rates

14 ate in vitro susceptibility to these agents, potentially affording additional treatment opportunities

15 present a trait abnormality for BD and could potentially aid clinical diagnosis.

16 isease spirochetes within tick vectors could potentially aid development of novel methods to control

17 ic use over established predictors and could potentially aid in surgical timing and risk stratificati

18 Rapid sediment clearance occurred that was potentially aided by mucus production.

19 als have the capacity for more rapid change, potentially aiding the adaptation of long-lived corals.

20 patient-derived samples, and will therefore potentially allow the identification of cell-to-cell com

21 bs) can be produced by muscle cells in vivo, potentially allowing prevention or treatment of infectio

22 es, like the a-factor pheromone, which could potentially also transport farnesol for virulence and qu

23 ahydrocannabinol in juvenile-adolescents, by potentially altering reward behavioral outcomes.SIGNIFIC

24 ma for a randomised phase 3 trial that might potentially answer this question definitively.

25 atile template for patterning soft materials potentially applicable as scaffolds in cardiac tissue en

26 roach for generating skeletal muscle that is potentially applicable to other pluripotent cell lines a

27 eby implying high-risk quantitative severity potentially appropriate for interventions but because of

28 Mobility differences potentially arise from strain or surface effects origina

29 We show that at least 4 introductions, but potentially as many as 40, contributed to the outbreak i

30 angle regression was used to select the most potentially associated single-nucleotide polymorphisms (

31 t is known to sense several stimuli that are potentially associated with the host, including extracel

32 l information toward identifying individuals potentially at risk for cognitive decline associated wit

33 heart of some forms of infertility and could potentially be addressed therapeutically by alternative

34 making during process development and could potentially be applied to control in biomanufacturing.

35 This approach can potentially be developed into a single-molecule toolbox

36 Instead, chemical formulations could potentially be developed to achieve novel pharmacokineti

37 dependence of R2* and R2 using the CFM could potentially be exploited as a tool to differentiate betw

38 ween nerves and endothelial metabolism could potentially be targeted as an anticancer therapy.

39 articipants and makes predictions that could potentially be tested with neurophysiological recording

40 These classifications can potentially be used for patient stratification and thus

41 ontal breakdown in both CP and AgP and could potentially be used for prevention and therapy of this g

42 e rising stars in materials science that can potentially be used to develop next-generation displays

43 ivo model and breast cancer cells, and could potentially be utilized as an adjuvant therapeutic to en

44 Identification of individuals who potentially benefit from preventive endografting is high

45 er objectives included financial protection (potentially better provided upstream by keeping people o

46 eering synthetic circuits are: (i) sRNAs can potentially bind nascent mRNAs in the nucleoid, and (ii)

47 h an initial clinical screening and followed potentially by dermoscopic analysis, a biopsy and histop

48 eage inhibit hematopoiesis and bone healing, potentially by producing excessive amounts of Dipeptidyl

49 protein, either by targeting slit-1 mRNA or, potentially, by modulating the canonical Notch pathway.

50 ive diagnostic methods that can mitigate the potentially catastrophic effects of infectious outbreaks

51 Consequently, prevention of these potentially catastrophic injuries is vital, and practiti

52 ogether suggest that vitamin D deficiency is potentially causal of sero-negative RA and provide new i

53 and cellular stress response (CSR) capacity, potentially causing species-related differences in uptak

54 pass through narrow luminal sections without potentially causing trauma to tissue with a traditional

55 ts on climate-sensitive infectious diseases, potentially changing their spatial distributions, affect

56 In addition, we find potentially clinically actionable PI3K signalling mutati

57 eral immune events, neuronal processing, and potentially cognition.

58 in and will guide its further development to potentially combat TB in HIV-endemic areas.

59 n was suggestive for complex inheritance and potentially complex gene product interactions during dev

60 Cardiogenic shock is a high-acuity, potentially complex, and hemodynamically diverse state o

61 y change using chi-squared tests to identify potentially confounding covariates, and logistic regress

62 When the FCAT test scores were adjusted for potentially confounding maternal and infant variables, c

63 shift were instead driven by male migration, potentially connected to new technology and conquest.

64 ap between each of the three magmatic pulses potentially constrains the recharge duration of a single

65 uninformative for optimal analysis and which potentially contribute to gaps in sequence coverage of p

66 gh the impairment of endogenous NPY release, potentially contributing to heightened anxiety.

67 t in primary glioblastomas before treatment, potentially contributing to relapse.

68 ed the effect of green living environment in potentially countering incident depression in a national

69 Strategies and potentially counterproductive activities for building pe

70 Together, these programmed effects will potentially create an imbalance between insulin secretio

71 rograms at an early stage are candidates for potentially curative therapies (local ablation, resectio

72 ement or to treat tachycardiomyopathy and is potentially curative.

73 Third, after completion of recombination, potentially dependent on SUMOylation, Mer2 mediates glob

74 Perioperative bleeding is a potentially devastating complication in neurosurgical pa

75 Our results demonstrate a potentially devastating impact of Disc1 deficiency on ne

76 RNA helicase MOV10 on mRNA degradation, the potentially different ADAR1 binding behaviors related to

77 heterozygous nonsense mutations in four and potentially disease-causing missense variants in two fam

78 his method represents the upper limit of the potentially dispersible nanoparticulate fraction, thus p

79 future directions to inform investigators of potentially disruptive NM technologies that have to be i

80 y in acute infection on disease progression, potentially driven by interaction of multiple genes rath

81 ore direct approaches are required to reveal potentially druggable binding sites.

82 ession patterns of some cancer driver genes, potentially due to aberrant hypomethylation of distal CG

83 that loss of Fdxr led to embryonic lethality potentially due to iron overload in developing embryos.

84 tion caused an increase in respiration rate, potentially due to the energetic cost of mucus productio

85 for ebolaviruses is possible but difficult, potentially due to the rarity of bNAb clones and their p

86 ovides valuable information by identifying a potentially effective target gene for managing BPH popul

87 of each molecular abnormality and to propose potentially efficacious combinatorial therapy regimens.

88 get-based approach in connecting diseases to potentially efficacious drugs.

89 productive tract tissues, kidney, and liver, potentially emulating key features of human ZIKV infecti

90 aviors are observed using the gold nanopore, potentially enabling new capabilities in biosensing, seq

91 al Neisseria species also contain genes that potentially encode fHbp, although the functions of these

92 rent from bulk sequencing of tumors, and can potentially establish whether specific mutations are mut

93 HV of diamond-like materials approaching or potentially exceeding the hardness of the diamond indent

94 the up- and down-conversion quantum yields, potentially exceeding the Shockley-Queisser limit for ph

95 This peptidomimetic/free radical system is a potentially excellent template for the preparation of a

96 sustainable biogas upgrading technology and potentially expands the application of microbial electro

97 These results potentially explain the convergence of global deep water

98 ink Tie2 dimers into higher-order oligomers, potentially explaining how Tie2 is differentially cluste

99 of doping-gradients toward grain boundaries, potentially explaining the extended photocarrier lifetim

100 ess and increased apoptosis in the pancreas, potentially explaining the loss of pancreatic cells and

101 on HR in human cells together with HsRAD51, potentially explaining the synergistic effect of attenua

102 Similar findings in potentially exposed adults suggest that clinicians shoul

103 Zika virus infection but not for all infants potentially exposed to Zika virus in utero.

104 als (PdM, M = V, Mn, Fe, Co, Ni, Zn, Sn, and potentially extendable to other metal combinations) with

105 eage-specific physiological adaptations that potentially facilitated salmonid species radiation.

106 Hereditary angioedema is a disabling, potentially fatal condition caused by deficiency (type I

107 Long-QT syndrome is a potentially fatal condition for which 30% of patients ar

108 Mutations in ATP7B cause the potentially fatal hepatoneurological disorder Wilson dis

109 igration is a viable strategy for minimizing potentially fatal interactions among ALAN, structures, a

110 as effective as high-dose prednisolone with potentially fewer adverse effects.

111 r the treatment of Huntington's disease, and potentially for other neurodegenerative disorders.

112 for the pancancer use of targeted drugs and potentially for the design of combination therapies.

113 lecular stratification to guide therapy and, potentially, for molecular diagnostics.

114 d electron-capture detection to identify the potentially formed byproducts.

115 Our results provide a novel example of a potentially general mechanism whereby climate change-med

116 stress than more tolerant hardwood species, potentially giving hardwoods a competitive advantage in

117 The potentially global extent of animal-induced regularity i

118 Although Sudan could potentially grow more wheat if irrigation is available,

119 ave been targeted for martian exploration as potentially habitable environments and as possible repos

120 eration and how cells are protected from the potentially harmful action of apoptotic caspases is larg

121 This activity is potentially harmful requiring mechanisms for tight repre

122 ly fine-tuning AP conduction velocity, which potentially has wide implications for the temporal trans

123 col, the 2/4-minute adenosine protocol would potentially have changed 332 of 1732 (19%) positron emis

124 Aberrant melanosomal morphology may potentially have consequences on the ability of the cell

125 gs more than doubled and the prescription of potentially hazardous antipsychotics halved after the in

126 n diameter and contains a diverse mixture of potentially hazardous constituents and opportunistic pat

127 The use of biomarkers can therefore potentially help avoid unnecessary morbidity from high-d

128 Induced pluripotent stem cells could potentially help to elucidate the complex mechanisms of

129 derived from bacterial biofilms, which have potentially higher rRNA:mRNA ratios and higher rRNA carr

130 isms that might remain active in cancers and potentially highlight the presence of feedback as an ind

131 stability and toxicity still remain that may potentially hinder their commercialization.

132 e, although the capacity for such a shift is potentially hindered by the compatibility of different h

133 t copper-induced fragmentation reactions can potentially identify different classes of polyether iono

134 Thus, it can be potentially implemented as a pretesting tool to identify

135 Within this context, there are potentially important benefits of providing social suppo

136 s pattern of results points toward DNAm as a potentially important biological mechanism through which

137 However, this potentially important carbon pool is poorly quantified i

138 Potentially important differences were seen in: testing

139 This article provides information on potentially important issues related to the off-label tr

140 es in accessible community-based venues is a potentially important public health strategy.

141 rategies aim to reduce the risk of DGF could potentially improve graft survival in DCD kidney transpl

142 An open scanner design may potentially improve tolerance of cardiac MRI and therefo

143 on decreases the risk of low birthweight and potentially improves other infant health outcomes.

144 reparation with directional atherectomy (DA) potentially improves outcomes of DCB.

145 ould also raise awareness among communities, potentially improving dengue control efforts.

146 on myelin deficit in preclinical animals and potentially in para-clinical human biopsy.

147 e powerful psychological influences and thus potentially increase the utilization of these suboptimal

148 A potentially increased specificity of CT was found in det

149 idemiological data identified countries with potentially increasing trends of liver cancer for preven

150 ce of immunoglobulin G almost until weaning, potentially indicating prolonged trans-intestinal transf

151 tand, unrealistic in terms of timelines, and potentially infeasible for logistical implementation.

152 viruses and 30% of the contigs in the study potentially infect Synechococcus.

153 mically distinct litter, invasive plants may potentially influence the fate of organic matter associa

154 eedback pathway targets multiple cell types, potentially influencing both motor output pathways and n

155 nto organo-mineral interactions, which could potentially inform land-carbon models that explicitly in

156 . GluA1/2R) to isolate RNA aptamers that can potentially inhibit both AMPA and kainate receptors.

157 ffective, but the phage genome-which encodes potentially inhibitory gene products-is still allowed to

158 ould be to prohibit or more closely regulate potentially injurious ingredients and thus promote publi

159 press let-7 targets, as these could serve to potentially intercede in tumors driven by loss of let-7

160 a transgene can disrupt an endogenous gene, potentially interfering with interpretation of the pheno

161 d benefits of an intervention is complex and potentially introduces uncertainty into the analysis, se

162 cialization and to reveal novel participants potentially involved in fibre metabolism regulation and

163 coding and regulatory elements for 608 genes potentially involved in obsessive-compulsive disorder in

164 remodeling, as well as enkephalin and RUNX3, potentially involved in the increased T-helper 1 cytokin

165 , FPOP analysis at the residue level reveals potentially key interacting residues.

166 mensals are essential to skin health and can potentially lead to disease when their abundances and ac

167 , bacteria produce partner proteins that can potentially lead to enhancement of transcription, transl

168 larities between the two isoforms, which can potentially lead to functional differences with signific

169 anistic understanding of its development and potentially lead to strategies to prevent ototoxic effec

170 audience is large and personally connected, potentially leading to both a broad and deep engagement

171 nt cells, driving their clonal expansion and potentially leading to leukemia.

172 tems, and changes in phenotype are observed, potentially leading to the identification of new growth

173 ity for a intrauterine fetal intervention in potentially lethal cases.

174 cell- and cytokine-mediated pathology during potentially lethal malaria infections.

175 Pneumocystis pneumonia (PCP) is a potentially lethal opportunistic infection that primary

176 Hymenoptera venom allergy is a potentially life-threatening allergic reaction following

177 Stroke and potentially life-threatening complications, such as annu

178 Therapy-related myeloid neoplasms are a potentially life-threatening consequence of treatment fo

179 Angioedema is a potentially life-threatening occurrence that is encounte

180 lignment-based methods, its applications are potentially limited, because of biases due mostly to seq

181 active chemical species reaching the sample, potentially limiting application efficacy.

182 s uncover new mechanisms by which AMPK could potentially maintain cellular energy homeostasis indepen

183 nomena pervade the lives of these apes, with potentially major implications for their broader evoluti

184 hinery for expression of its complete genome potentially makes it vulnerable to modulators of RNA spl

185 microbiota, like rhizosphere microbiota, can potentially mediate plant species coexistence via negati

186 In this paper we have described a potentially miniature fiber-optic vibrometer based on a

187 ay, retrotransposons are divided into young, potentially mobile elements, and old that moved thousand

188 As a potentially modifiable condition, it is of particular im

189 n-nutritive sweetened beverages [NNSBs]) are potentially modifiable risk factors contributing to vari

190 , predict mortality in many cancers, and are potentially modifiable.

191 , while many roving predators are present or potentially more abundant in deeper strata (30-100 m+),

192 an informed decision may lead to earlier and potentially more effective interventions.

193 ifungal susceptibility testing (AFST) of the potentially multidrug-resistant pathogen Candida glabrat

194 e formation of photoproducts in DNA that are potentially mutagenic if not properly removed by the nuc

195 us prematurely deceased females indicating a potentially mutualistic association.

196 en to identify areas of funding strength and potentially neglected populations.

197 The work introduces a potentially new application for a broad range of micro-

198 orks in relation to asthma severity provided potentially new insight into biological mechanisms assoc

199 s study suggest mechanistically distinct and potentially nonredundant roles for high- and low-affinit

200 n contribute to the development of tools for potentially normalizing executive dysfunction in patient

201 sted that the SCN5A and KCNE1 lead SNPs were potentially novel and population-specific.

202 species, indicating that tardigrades possess potentially novel mechanisms for surviving desiccation.

203 Intracranial Injury Decision Aid score is a potentially novel tool to risk stratify this population,

204 rettes) use has increased globally and could potentially offer a lower risk alternative to cigarette

205 ate that co-targeting of ROS1 and EGFR could potentially offer an effective oral cancer therapy.

206 tin cytoskeleton and plays a part in several potentially oncogenic signaling networks.

207 or proper development of salivary glands and potentially other exocrine glands.

208 al indication for dose reduction, 43.0% were potentially overdosed, which was associated with a highe

209 This article reviews several potentially paradigm-changing mechanisms enabled by defe

210 validation of known genetic risk factors and potentially pathogenic alleles identified in future stud

211 insights into the role of bacteriophages as potentially pathogenic for mammals and their possible im

212 We used genomic sequencing to identify potentially pathogenic gene variants in families in whic

213 THAP11 by Sanger sequencing and discovered a potentially pathogenic, homozygous variant, c.240C > G (

214 many chemicals are falsely assigned as being potentially persistent based on results from BSTs.

215 s are experiencing substantial erosion, with potentially pervasive effects on ecosystem functions and

216 After removing potentially pleiotropic single nucleotide polymorphisms

217 hat appeared to accumulate pyrin; this could potentially precipitate inflammasome assembly.

218 , genotype-differentiating metabolites could potentially predict IBD risk.

219 une-modulatory effects of nilotinib in vivo, potentially predicting response to therapy.

220 n emerging role for germline genetic testing potentially predicting sensitivity to platinum salts and

221 g genes are up-regulated in the mature cyst, potentially preserved as mRNA in preparation for excysta

222 Policies and strategies addressing potentially preventable ED visits should be promoted to

223 Potentially preventable spending was calculated by summi

224 The amount and proportion of potentially preventable spending were then compared acro

225 asing public health problem, despite being a potentially preventable tragedy.

226 and histone retention in mature spermatozoa, potentially priming certain regions of the genome for ra

227 imental human colonization with a commensal, potentially probiotic E. coli bacteriuria strain.

228 This is potentially problematic, since prior immunity to a scaff

229 st way of identifying this characteristic as potentially problematic.

230 -state binding, through the sampling of many potentially productive conformations.

231 nant gp120 vaccine induced higher-magnitude, potentially protective anti-V1V2 IgG responses than in a

232 to short time scales, the fossil record can potentially provide a quantitative archive of long-term

233 from the immune system of sea urchin larvae potentially provide insights into immune signaling in an

234 ; the use of whole cell microbial biosensors potentially provides an alternative, fast, and efficient

235 surements of cell-generated frequency noise, potentially providing a basis for rapid AST.

236 phenotype in the absence of growth factors, potentially providing an eventual therapy to prevent OA.

237 l best respond to anti-PD-L1 treatment while potentially providing key information to limit immune-re

238 Many compounds with potentially reactive chemical motifs and poor physicoche

239 aline concentration had little effect on HR, potentially reflecting down-regulation of cardiac beta-a

240 ls own internal degrees of freedom, which is potentially related to the controllability of domain wal

241 negative DPD values are commonly calculated, potentially related to the use of mean pulmonary artery

242 The signal characteristics of the Bagel Sign potentially represent venous engorgement and/or acute bl

243 etection of approaching objects from behind, potentially representing an adaptation compensating for

244 ion-dependent histone genes on chromosome 6, potentially representing the chromatin architecture at t

245 nces like drugs can affect the epigenome and potentially rescue genetically determined disease phenot

246 vation may reflect a neuroinflammatory state potentially responsive to the immune regulators such as

247 s will be disinhibited; and thus, this could potentially result in increased reward.

248 tumour resistance to therapeutic agents, and potentially screen individuals for the early diagnosis o

249 hus, early sound experience can activate and potentially sculpt subplate circuits before permanent th

250 hich encompassed the Bhmt gene and defined a potentially sensitive region with mostly decreased methy

251 with the high levels of exposure, indicate a potentially serious human health burden from air polluti

252 be of limited clinical relevance, they could potentially serve as reservoirs of antimicrobial resista

253 distinct electrophysiological properties and potentially serving different functions.

254 ed and inflamed causing diverticulitis, with potentially severe complications.

255 prevalent chronic neurological disorder with potentially severe mental and physical health consequenc

256 e to increasing temperatures, representing a potentially significant positive feedback within the cli

257 rompted by these results, which underscore a potentially significant role of 5RK in exocytosis, we ne

258 able Aspergillus exposure in patients with a potentially similar clinical risk.

259 ution of mantle composition since 550 Ma and potentially since the onset of plate tectonics.

260 still be recovering from past disturbances, potentially skewing our interpretations of forest dynami

261 y and efficiently generate forces that could potentially slide microtubules apart.

262 metal loadings are poorly characterized but potentially substantial sources of trace metals to the l

263 vironment and landfills can be a long-term, (potentially) substantial source of PFOS.

264 ion channels at late prophase and telophase, potentially suggesting roles for such channels in cell d

265 nce of Ae. albopictus in areas identified as potentially suitable for transmission given our uncertai

266 ile, and efficient access to derivatives and potentially superior analogs.

267 they demonstrate that natural computing can potentially support long and complex computations.

268 creasing the Vif-Pr55(Gag) interaction could potentially suppress virus proliferation, this approach

269 uggest that S-palmitoylation of JAM-C can be potentially targeted to control cancer metastasis.

270 Potentially, targets will be consumed at 1 M per day pe

271 e possibility for further studies of NSs and potentially the design of attenuated viruses for vaccina

272 affecting the supply of rhesus macaques and, potentially, their responses to experimental treatments.

273 cannabidiol, which is a non-intoxicating and potentially therapeutic component of cannabis, has been

274 these novel biosensors can be used to reveal potentially therapeutic dopamine D1 receptor and adenosi

275 d with increased risk for persistent asthma, potentially through modulating susceptibility to early a

276 gatively regulated by miR-29 overexpression, potentially through the regulation of peroxisome prolife

277 ls behavior through an allocentric mechanism potentially tied to the hippocampus, others postulate th

278 y evolved to increase glycosylation of TSRs, potentially to increase the stability of the structurall

279 e elevation in A53T mice increased levels of potentially toxic alpha-synuclein oligomers, resulting i

280 of its natural inhibitor ammonium to prevent potentially toxic cross-linking activity.

281 on results in retinal iron-dyshomeostasis, a potentially toxic host response contributing to prion di

282 While most therapeutic approaches involve potentially toxic immunosuppressive strategies, the path

283 The mean number of pre-migration potentially traumatic events was 2.1 (SD 1.4).

284 d treated for cancer is highly stressful and potentially traumatic.

285 tion with biologically active factor H could potentially treat a variety of diseases that involve inc

286 sperm DNA enters oocyte cytoplasm and could potentially trigger a response.

287 t pathogens sporadically infect naive hosts, potentially triggering epizootics.

288 halogenases and provides new insights into a potentially unique reaction mechanism.

289 g and low thermal budget make our strategy a potentially universal approach to integrating functional

290 unreliable and unpredictable, and therefore potentially unsafe.

291 ort a 3D microfluidic platform that could be potentially used for a real-time deterministic analysis

292 s crucial regulators in cancer processes and potentially useful as biomarkers for cancer diagnosis an

293 Hippocampal tail volume is proposed as a potentially useful biomarker of sensitivity to ADM treat

294 or natural differentiation and predicts some potentially useful combinations of TFs.

295 Chk1 inhibitors may be a potentially useful therapeutic treatment for patients wh

296 g red blood cell formation, results that are potentially useful to treat certain anemias.

297 monomer, but also forms dimers and trimers, potentially via a coiled-coil alpha-helix.

298 for mood and anxiety disorders and suggest a potentially wider therapeutic overlap between AEA and 2-

299 imals against ZIKV challenges, but their use potentially will predispose vaccinated individuals to in

300 coupled to high throughput, this method can potentially yield preparation times as low as 15 s per s