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1 antagonist blocked and A3AR agonist strongly potentiated).
2 ses undergo depression, whereas SMn synapses potentiate.
3 was reduced while glycinergic inhibition was potentiated.
4 three copies of the alpha4 subunit that are potentiated.
5 bidirectional synapses can be preserved and potentiated.
6 m interneurons only GABAergic responses were potentiated.
7 sitization was reduced and latent inhibition potentiated.
8 tion of CIB1 in primary dopaminergic neurons potentiated 1-methyl-4-phenyl pyrinidium (MPP(+))-induce
10 l elevated cAMP levels by itself and further potentiated a forskolin-induced increase in cAMP levels
11 tion with the NAMPT substrate, nicotinamide, potentiated a subthreshold dose of P7C3-A20 to full effi
14 ng fear extinction, and Gq-DREADD-induced DA potentiated activity of D1-expressing neurons in both th
15 hesis is that misfolded IAPP produced in T2D potentiates AD pathology by cross-seeding Abeta, providi
18 trate that T can rapidly (within 60 minutes) potentiate aggressive behavior, but only among men with
21 late maintenance of persistent TH2 cells and potentiate allergic inflammation are not well understood
24 s that exogenous administration of T rapidly potentiates amygdala and hypothalamus responses to angry
25 -mesenchymal transition (EMT) markers and to potentiate an epigenetic mechanism of the TGFbeta respon
28 e the phenylpropanoid and terpenoid pathways potentiated and have a faster and stronger transcription
30 etylcholinesterase, which can also activate, potentiate, and inhibit acetylcholine receptors, includi
31 ses AngII receptor type I a expression, thus potentiating AngII signaling in vascular smooth muscle c
33 is an effective antibiofilm agent that could potentiate antibiotic efficacy in infections associated
36 kappaB inhibitors reduced p27 expression and potentiated apoptosis in thyroid cancer cells while not
38 ity and insulin secretory rates from glucose-potentiated arginine and mixed-meal tolerance tests (MMT
40 establish LKB1 as the key node whereby BITC potentiates as well as rescues p53-pathway in p53-wild-t
41 three copies of alpha4 and two of beta2 was potentiated at low concentrations of acetylcholine chlor
45 studies have shown that the binding site for potentiating betaEST is in the C-terminal (post-M4) regi
46 dulation of NK cell functional maturation to potentiate both tumor immunosurveillance and viral clear
47 he exact same 5 ms pairing in stratum oriens potentiated both pathways, as did AP-bursts alone, which
48 factor (GDNF) to increase cocaine intake was potentiated by a deletion that abolished its HS binding.
50 induction of Ca(2+) release by FXa that was potentiated by APS-IgG and SLE/APS- IgG compared to heal
52 thermore, this anti-BCL2 effect was markedly potentiated by concurrent HDAC inhibition with 93% of sa
53 st and induces apoptosis, the latter further potentiated by concurrent PI3K/MEK inhibition, consisten
54 tivity of IP anticancer drugs can be further potentiated by encapsulation in nanocarriers and/or affi
55 uggest that the neural fixation circuitry is potentiated by engaging stationary objects, and interact
59 e of ovarian cancer cells to pitavastatin is potentiated by farnesyl diphosphate synthase inhibitors
62 nificant benefits and that its action can be potentiated by nanobubble agents to result in improved d
65 ivation, whereas TRPC4/5 channel activity is potentiated by phosphatidylinositol 4,5-bisphosphate (PI
66 were prevented by PKMzeta overexpression and potentiated by PKMzeta inhibition in subthreshold stress
67 he ARC(Glutamatergic)-->PVH(MC4R) synapse is potentiated by the ARC(POMC) neuron-derived MC4R agonist
70 induced Syk and PLCgamma2 phosphorylation is potentiated by TxA2 and that TxA2 plays a critical role
73 HIPK1-phosphorylated PAGE4 (HIPK1-PAGE4) potentiates c-Jun, whereas CLK2-phosphorylated PAGE4 (CL
75 gradation similar to the effect of forskolin-potentiated cAMP formation, suggesting that Thr306 in Sm
78 , RNF43 and ZNRF3 receptor classes, markedly potentiate canonical Wnt/beta-catenin signalling, and in
80 t functional fat-1 and topically applied DHA potentiate cellular defense against UVB-induced skin inf
83 ies of corticosterone and normetanephrine to potentiate cocaine-primed reinstatement in OCT3-deficien
84 mic stress-level corticosterone treatment to potentiate cocaine-primed reinstatement was recapitulate
86 ys showed that sigma1R agonist preincubation potentiated cocaine-induced changes in DAT conformation,
87 produced stress-level plasma concentrations) potentiated cocaine-primed reinstatement of extinguished
88 ctly test the hypothesis that corticosterone potentiates cocaine-primed reinstatement by blockade of
89 a-mitochondrial influx of Ca(2+) induces and potentiates CoMIC, and leads to K(+)-mediated mitochondr
90 exhibited increased striatal activation and potentiated corticostriatal functional connectivity betw
92 rom the venom of Conus textile that strongly potentiated currents of ASIC3, which has a specific role
93 endritic cells we found that high salt media potentiates cytokine expression downstream of TLR4 activ
94 In cultured male DRG neurons, IP3 (100 mum) potentiated depolarization-induced transients produced b
95 ysiology, we identified the binding site for potentiating dFBr on the top half of a cavity between th
96 a mechanism by which the presence of T1-IFN potentiates diabetogenicity within the autoimmune islet.
100 A novel peptide producing a significant potentiating effect on allyl isothiocyanate- and diclofe
101 imilar index is also derived to quantify the potentiating effects of positive allosteric modulators,
102 ogic provides templates of progenitor cells' potentiating effects, and components affecting human bra
104 r endothelial growth factor (VEGF) crosstalk potentiates endothelial network formation and hepatoblas
105 We also demonstrated that ISG15 silencing potentiates enhanced type I IFN-mediated signaling, resu
106 report that interfering with PD-1 signaling potentiates epitope spreading in tumor-specific response
108 affin cells, we show that PI(4,5)P2 uncaging potentiates exocytosis and identify synaptotagmin-1 (the
109 reveal a key role for the IL-6/STAT3 axis in potentiating FGF19-driven HCC in mice, a finding which m
111 downstream B cell recruitment, which further potentiated fibrosis, as confirmed by B cell knockout an
112 positive feedback loop involving sialidases potentiates fibrosis, and suggest that sialidase inhibit
114 uced anticipatory pursuit, suggesting that a potentiated fixation system interacted with pursuit to s
116 that activity at the reverse-strand EBE also potentiates forward transcription driven by activity at
118 Galphaq-PLC-beta3 dissociation or PLC-beta3-potentiated Galphaq deactivation, is not sufficient to e
120 We show that MRAP2 interacts with GHSR1a and potentiates ghrelin-stimulated signaling both in vitro a
122 f three benzothiadiazine-based modulators to potentiate glutamate-evoked currents at recombinantly ex
123 1,2,4-benzothiadiazine 1,1-dioxide (BPAM344) potentiated glutamate-evoked currents of GluK2a 21-fold
128 dampening low-frequency excitatory input and potentiating high-frequency sustained currents at second
131 the single-cell level by showing that IL-33 potentiates IgE-mediated mast cell responses by both inc
133 nd outcomes within and among systems, and it potentiates improvement toward more patient-centered and
134 usceptibility to RA teratogenesis is further potentiated in embryos with a preexisting genetic defect
135 holipase C (PLC) activity were significantly potentiated in hepatocytes from alcohol-fed rats compare
141 iR-34 family and confirmed that these miRNAs potentiate interferon regulatory factor 3 (IRF3) phospho
143 on of ryanodine (2 nm), instead of IP3, also potentiated K20-induced calcium transients in the presen
147 oth sleep deprivation and caffeine treatment potentiated light-induced c-Fos expression in calbindin-
148 rivation in early night, but not late night, potentiated light-induced c-Fos expression in the ventra
149 oth sleep deprivation and caffeine treatment potentiated light-induced phase delays and phase advance
150 nd, to a lesser extent, EP4 receptor agonist potentiated LPS-induced IL-33 generation from both mPGES
151 e find that P. aeruginosa LasA endopeptidase potentiates lysis of S. aureus by vancomycin, rhamnolipi
152 al dysfunction and metabolic distress, which potentiate maladaptation to stress and susceptibility to
153 ediated by alpha1beta2gamma2 receptors, also potentiated maximal currents mediated by alpha1(D43C)bet
155 DAOY, OGR1 promoted expression of the proton-potentiated member of the canonical transient receptor p
157 der to develop a treatment strategy based on potentiating mitochondrial function, we investigated the
158 rphine binding to PAG TLR4 with (+)-naloxone potentiated morphine antinociception significantly in fe
160 appaB activation, whereas knockout of LRRC25 potentiated NF-kappaB activation and enhanced the produc
161 lidinones, such as PYD-106, that selectively potentiate NMDA receptors that contain the GluN2C subuni
162 supports the ability of PDE2A inhibitors to potentiate NMDA signaling and their further development
163 tension, the molecular mechanism involved in potentiated NMDAR activity of hypothalamic presympatheti
165 pendent NMDAR blocker, MK-801, indicate that potentiated NMDARs reside on the plasma membrane and are
166 e phosphodiesterase-5 inhibitor, sildenafil, potentiates NO signaling to inhibit platelet function.
170 therapy with TLR4 ligands might be useful to potentiate oral tolerance to haptens and alleviate ACD i
171 s typically applied to blood samples and has potentiated our understanding of the relation between im
172 on, and in this study we found that morphine potentiates P2X7R-mediated Ca(2+) responses in resident
173 shortened from 10 to 5 ms, which selectively potentiated paired radiatum pathway, since unpaired orie
174 ition, and point at combination therapies to potentiate PARP inhibitor treatment of HR-deficient tumo
176 lating oostatic factor/TMOF and a bradykinin-potentiating peptide, BPP-12b) were all inhibitors of th
179 Infection and inflammation play a role in potentiating PH and pro-inflammatory cytokines, includin
180 Disruption of either MHC class I or LILRB1 potentiated phagocytosis of tumor cells both in vitro an
181 The data explain why rigid collagen fibrils potentiate PI3K activation to promote malignancy and off
182 y is increased in the PVN and contributes to potentiated presynaptic and postsynaptic NMDAR activity
184 subunit 85 (MBS85), paxillin and CPI-17 (PKC-potentiated protein phosphatase 1 inhibitor protein of 1
185 eduction was not due to passive decay of the potentiated pursuit signal because interleaving "blank"
188 promote reinstated sucrose seeking, nor was potentiated reinstatement after mGluR2/3 blockade reduce
190 istration and extinction, but each treatment potentiates reinstatement in response to an otherwise su
192 s such as NS9283 and CMPI have been shown to potentiate responses of (alpha4)3(beta2)2 but not (alpha
193 ed: concentration, set switching, inhibiting potentiated responses, and monitoring and checking.
194 lls by their autologous T cells in vitro and potentiates responses to anti-CTLA4 and anti-PD1 therapy
195 to revert a possible negative effect and to potentiate responsiveness to antiangiogenic therapy by c
196 ute enhancement of dopaminergic transmission potentiated reward-related striatal activation and corti
199 us work, the membrane bound form of Cripto-1 potentiated signaling, revealing a critical role of memb
200 nce in potency of the positive modulators in potentiating SK2 channel activity may be attributed prim
203 n vivo studies show that denileukin diftitox potentiates standard TB treatment in the mouse model, an
204 recall of threat memory, measured with fear-potentiated startle 7 days after acquisition, is attenua
205 also associated with HDAC4 expression, fear-potentiated startle and resting-state functional connect
207 lator is controlled by B cell activation and potentiates steady-state and postimmune antibody product
208 the stochasticity of GAL gene expression and potentiates stronger GAL gene activation in the presence
212 both pathways, as did AP-bursts alone, which potentiated synaptic efficacy as well as current-evoked
213 s provide evidence that HSP90 inhibition can potentiate T-cell-mediated anti-tumor immune responses,
215 measures of anxiety (ICC = 0.66) and threat-potentiated task performance (ICC = 0.58) showed clinica
218 CM, into the topical EPO-containing gel, can potentiate the accelerating action of EPO on the healing
221 of potent KPC-2 and NDM-1 inhibitors able to potentiate the activity of cefotaxime (CTX) and ceftazid
222 marine natural product, has been reported to potentiate the activity of choline acetyltransferase (Ch
223 Here, we review another checkpoint acting to potentiate the activity of innate immune cells towards c
224 e NanI activity, which in turn could further potentiate the activity of intestinally active toxins du
226 analyses showed that the WARS mutation could potentiate the angiostatic activities of TrpRS by enhanc
228 argeting of different silencing pathways can potentiate the establishment of off-target epialleles.
229 t combinations revealed that the two isomers potentiate the induced-inhibition of protein geranylgera
231 eep deprivation and caffeine-induced arousal potentiate the photic entrainment in a diurnal rodent.
232 ers a therapeutically applicable approach to potentiate the regenerative outcome in the injured CNS.
234 DNA adducts, 1,2-intrastrand cross-links, to potentiate the sensitivity of TGCTs to cisplatin therapy
238 prototypical sigma1R agonist (+)-pentazocine potentiated the dose response of cocaine self-administra
239 kinase inhibitor cabozantinib, dramatically potentiated the drugs' individual antitumor effects in a
241 pairing aTreg-mediated immunosuppression and potentiated the effects of anti-PD-1 immunotherapy.
245 ouse model of glioma, we found that Cic loss potentiated the formation and reduced the latency in tum
246 responses induced by the other variant even potentiated the in vivo effects of IL-1beta; the latter
248 n of N-acetylcysteine to isoniazid treatment potentiated the killing of Mtb Furthermore, we demonstra
249 lpha whereas silencing of endogenous CLIP170 potentiated the levels of proinflammatory cytokines.
250 aspects of native cartilage development, and potentiated the maturation of self-assembling hMSCs into
253 1,2,4-benzothiadiazine 1,1-dioxide (BPAM521) potentiated the recorded peak current amplitude of GluK2
254 ver, pyridostatin, a G4 ligand, specifically potentiated the translational suppressing effect of P1-H
257 nafil, a phosphodiesterase type 5 inhibitor, potentiates the actions of nitric oxide, which leads to
258 -approved drug, inhibits TORC1 signaling and potentiates the activity of the antifungals amphotericin
260 recipitation experiments revealed that FGF13 potentiates the binding of calmodulin to NaV1.5 and that
261 tion using specialized, virus-like particles-potentiates the cytotoxicity of Ara-C in AML cells.
263 ing a second compound, dexmedetomidine, that potentiates the effect of delivered local anesthetics.
264 ygen species scavenging properties that also potentiates the effects of nitroglycerin and thus repres
265 inactivation of RNF145 by genetic deletion, potentiates the expression of cholesterol biosynthetic g
266 tive dephosphorylation-resistant PKD1 mutant potentiates the IKK/NF-kappaB/SOD2 oxidative stress deto
267 d-insula of withdrawal signals from the body potentiates the motivational salience of reward cues thr
268 tly available for detection of breast cancer potentiates the need for development of novel, specific
269 tion of bone marrow-derived dendritic cells, potentiates the p65-dependent IL-6 and the p38-MK2/3-dep
270 ctivation and that its genetic variant I148M potentiates the profibrogenic features of HSCs, providin
271 ese data support the hypothesis that Ms 9a-1 potentiates the response of TRPA1 to endogenous agonists
272 tralization of vorinostat-induced IL-8/CXCL8 potentiates the vorinostat inhibitory effect on cell via
273 ls exhibited increased oxidative DNA damage, potentiating the acquisition of somatic mutations during
275 igand 1 signaling pathways were essential in potentiating the generation of DCs with tolerogenic prop
276 nd interdependent Brd2 and Brd4 functions in potentiating the genetic program required for Th17 cell
277 nd used for the binding assay, with (R,R)-68 potentiating the radioligand and (S,S)-68 displacing the
278 r exposure to bites of uninfected sand flies potentiates their ability to transmit infection to the v
280 acts synergistically with beta2-agonists and potentiates their positive effects on skeletal muscles.
281 and agonistic fusion proteins to inhibit or potentiate these molecules and pathways in cancers and a
283 es may allow tailoring of pharmacotherapy to potentiate thrombus instability, through fragmentation o
284 on site motif impaired the ability of VWA to potentiate TMEM16A activity, suggesting that CLCA1-TMEM1
285 eir ability to be selectively induced and/or potentiated to result in complete protection merits para
286 ecular dependencies that may be exploited to potentiate treatment with transarterial embolization (TA
288 PCRs agonists inhibited and inverse agonists potentiated TRPM3 mediated nociceptive behavioural respo
291 nd MEK/ERK/1/2 by ruxolitinib and trametinib potentiated tumor response to etoposide and increased ov
292 at one of the major mechanisms by which Muc4 potentiates tumor progression is via its engagement of t
294 paired radiatum and unpaired oriens pathway potentiated, unless the pre-post delay was shortened fro
295 vants that are considered biologically inert potentiate viral pathogenicity in honey bee larvae, and
296 fatty acid synthesis and beta-oxidation that potentiates WAT oxidative capacity and ultimately suppor
297 that acutely enhanced ACh tone significantly potentiated whisker-evoked CBF responses through muscari
298 LGR5 activation by R-spondin (RSPO) ligands potentiates Wnt/beta-catenin signaling in vitro; however
300 ctive Y4R positive allosteric modulator that potentiates Y4R activation in G-protein signaling and ar
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