ライフサイエンスコーパス: preassembled

1 ignaling components are compartmentalized or preassembled.

2 ether with E1b to degrade de novo-expressed, preassembled AAV5 capsid proteins and Rep52 in a proteos

3 lts show first that aneural myotubes contain preassembled AChR protein complexes that may function in

4 We show that preassembled actin filaments are cross-linked directly b

5 The persistence of preassembled and complete translocons between successive

6 ined size and having the same effect on both preassembled and growing FtsZ protofilaments.

7 Glycophosphorylation of preassembled and properly protected peptides was found t

8 d functional elongation complexes, by mixing preassembled and RNA-primed DNA "bubble" constructs with

9 Duct cell P2X7Rs are preassembled and therefore continually subject to rapid

10 Thus, the apicosome is a unique preassembled apical structure that can be rapidly used i

11 proximity measurements support formation of preassembled apo-GHSR1a:DRD1:Galphaq heteromeric complex

12 r assembly, and induced rapid disassembly of preassembled asters.

13 ng to rapid degradation, and Ste2-3p that is preassembled at the plasma membrane is also removed and

14 ed "threading," passing between parts of the preassembled beta-subunit.

15 related stopped-flow signals revealed that a preassembled beta.

16 y, simulations of these systems start from a preassembled bilayer because the timescale on which self

17 n of downstream signal transduction involves preassembled BRI1-BAK1(SERK3) heterooligomers.

18 blunt-ended alpha-helical barrels, that is, preassembled bundles of alpha-helices with central chann

19 One function of this cap may be to provide preassembled Ca(2+) channel components to existing and n

20 the structural effects of TRIM5 proteins on preassembled CA-NC complexes by electron microscopy.

21 odeling at cell-cell contacts and stabilizes preassembled cadherin complexes.

22 bacteriophage varphi29, DNA is packed into a preassembled capsid from which it ejects under high pres

23 molecular motors to translocate dsDNA into a preassembled capsid shell.

24 l molecular motor compacts the genome into a preassembled capsid.

25 Genomic DNA is inserted into preassembled capsids through a unique portal vertex.

26 pose that UL32 may play a role in "bringing" preassembled capsids to the sites of DNA packaging and t

27 eavage and packaging of herpesvirus DNA into preassembled capsids.

28 Preassembled CB1-Galphai complexes were detected by BRET

29 The LUBAC also participates in preassembled CBM complex in cells derived from ABC DLBCL

30 ing, which explains how they can inhibit the preassembled Cdk4/6-cyclin D complexes as well.

31 ing newly synthesized CENP-A and maintaining preassembled CENP-A at centromeres.

32 e of NURF in activating transcription from a preassembled chromatin template and have found that NURF

33 that Staf activates U6 transcription from a preassembled chromatin template in vitro and associates

34 (II)s are necessary for transcription from a preassembled chromatin template.

35 AP3 binds both inositol hexakisphosphate and preassembled clathrin cages with high affinity.

36 1) and Pt@Pb(1)(2)(1)(-) were prepared from "preassembled" clusters generated from crystalline sample

37 ds the need for liquid infiltration into the preassembled colloidal crystal and minimizes the associa

38 We demonstrate the approach using preassembled colloidal tetrahedra and spheres, obtaining

39 helial cells, PAR1 and beta-arrestins form a preassembled complex and cosegregate in caveolin-1-enric

40 l delta and Pol zeta catalytic subunits on a preassembled complex of accessory proteins retained on D

41 nity either to empty importin alpha5 or to a preassembled complex of importin alpha5 bound to the C-t

42 in vitro CCT-ACT1-PLP2 folding cycle of the preassembled complex takes 90 s at 30 degrees C, several

43 nactive heterotrimeric G proteins, forming a preassembled complex that is potentially braced for GPCR

44 The first of these assemblies is a preassembled complex with the receptor in its basal conf

45 OPII vesicles, implying their ER export as a preassembled complex.

46 ll three nonidentical CBF/NF-Y subunits in a preassembled complex.

47 ignals with both rapid reaction times of the preassembled complexes and efficient resupply at the mem

48 In contrast, preassembled complexes catalyzed strand transfer equally

49 ments have suggested stepwise recruitment of preassembled complexes, including chromatin remodeling,

50 ocking binding by Mnk1, which occurs only on preassembled complexes, resulting in dephosphorylation o

51 hibited catalytic activities of IN in IN-DNA preassembled complexes.

52 are unlikely to exist in stable constitutive preassembled complexes.

53 we introduce a new design principle based on preassembled components of the desired superstructure an

54 -negative Orai1 monomer along with different preassembled concatenated Orai1 constructs, we recently

55 hin the triad junction but do not exist in a preassembled context.

56 It aligns paired-end (PE) reads and preassembled contigs or scaffolds to a close reference.

57 Using microinjection of preassembled cores as a tool, a system has been establis

58 nelles, the fusiform vesicles, which deliver preassembled crystalline arrays of uroplakin proteins to

59 ng of Scm3 can replace histones H2A-H2B from preassembled Cse4-containing histone octamers.

60 Moreover, kinetic study of preassembled cube and tetrahedron demonstrated a slow li

61 microtubule assembly and cause breakdown of preassembled cytoplasmic microtubules in human polymorph

62 A preassembled DAMed complex bypasses the requirement for

63 ment and selection, we generated mice with a preassembled Dbeta1Jbeta1.1 complex on the Jbeta1(omega)

64 that a preassembled TCRbeta gene, but not a preassembled DbetaJbeta complex or the prosurvival BCL2

65 A preassembled DJbeta complex that decreases the number of

66 Finally, inclusion of an endogenous preassembled DJbeta complex that enhances Vbeta recombin

67 Gold electrodes modified with preassembled DNA duplexes are used to monitor the electr

68 The PNA-peptides were found to bind to the preassembled DNA nanocage in 5-10 min at room temperatur

69 oters on which Notch:CSL complexes have been preassembled, ensuring tight transcriptional control of

70 Co, Ni, Cu), have been synthesized using the preassembled [Fe3O(OOCCH3)6] building block.

71 gree in a Rho-independent fashion, gathering preassembled filaments to the equatorial zone via cortic

72 or approximately 25 s with the barbed end of preassembled filaments, inhibiting their elongation.

73 VopL/F do not associate with the ends of preassembled filaments.

74 Immunoprecipitation shows that large preassembled flagellar complexes containing all five tes

75 s subunit proteins can exist in immature and preassembled forms, but may execute cellular roles irrel

76 volatile anesthetics were introduced into a preassembled fully hydrated 512-molecule lipid bilayer a

77 Expression of either a preassembled functional TCRbeta gene (Vbeta1(NT)) or the

78 , Ccnd3(-/-), and Lat(-/-) mice containing a preassembled functional Vbeta1DJCbeta1 (Vbeta1(NT)) gene

79 nalyzed mice with TCRbeta alleles containing preassembled functional VbetaDJbetaCbeta1 genes.

80 aryltransferase (OST), PglB, which transfers preassembled glycans to specific asparagine residues in

81 de novo from the ER or whether it requires a preassembled Golgi matrix.

82 reas PIGT is essential for attachment of the preassembled GPI anchor to proteins.

83 l sequence and replaces this sequence with a preassembled GPI anchor.

84 nsists of a transamidation reaction in which preassembled GPI donors are substituted for C-terminal s

85 complex) with the ethanolamine moiety of the preassembled GPI unit serving as a nucleophile.

86 ase concentrations, occurs by threading of a preassembled helicase over free 5'-ends, an event that c

87 lishment of centromeric heterochromatin, but preassembled heterochromatin can be maintained when Chp1

88 f BMPRII exhibit confined motion, reflecting preassembled heteromeric receptor complexes.

89 ic reticulum (ER), catalyzes the transfer of preassembled high mannose oligosaccharides onto certain

90 ransferase (OST), involves the transfer of a preassembled high-mannose oligosaccharide from a dolicho

91 and Artemis-deficient B cells that harbored preassembled Ig heavy chain and kappa-light chain "knock

92 sayed CSR in Lig4(R/R) B cells generated via preassembled IgH and IgK V region exons (HL).

93 91, which demonstrates late association with preassembled IMV, also did not show any quenching.

94 transcription and processing components are preassembled in Cajal bodies before transport to the chr

95 We find that IL-15 and IL-15Ralpha are preassembled in complexes within the endoplasmic reticul

96 aining syntaxin-1, SNAP-25, and Munc18-1 are preassembled in microdomains on the presynaptic plasma m

97 yneins are multisubunit enzymes that must be preassembled in the cytoplasm, transported into cilia by

98 nein arm (ODA) motor complexes, produced and preassembled in the cytosol, are transported to the cili

99 ur data suggest that a WC-1/NGF-1 complex is preassembled in the dark on light-inducible promoters an

100 its surrounding a central channel, which are preassembled in the ER and transported in their final st

101 Eukaryotic ribosomes are preassembled in the nucleus and mature in the cytoplasm.

102 ts multimerize, and, if so, whether they are preassembled in the plasma membrane.

103 intrinsically stable prothrombinase complex preassembled in the venom gland of the Australian Easter

104 Importantly, the regulatory spine is preassembled in this gatekeeper mutant, rendering phosph

105 rangements in Vbeta14(Rep) mice containing a preassembled in-frame transgenic Vbeta8.2Dbeta1Jbeta1.1

106 FBG preassembled into matrix prior to scrape-wounding induce

107 Lys-174, Arg-239, Asn-280, and Tyr-289) are preassembled into the active site in the absence of DNA

108 In X. leavis M phase extracts, preassembled kinetochores disassemble after inhibiting A

109 recognition, or when added exogenously to a preassembled lipid vesicle complex, underscoring the imp

110 ry systems, with approximately 25% acquiring preassembled metal cofactors.

111 ters requires its direct interactions with a preassembled MHC-II enhanceosome consisting of cyclic AM

112 ls moderate binding affinity between tau and preassembled microtubules and rapid dissociation/associa

113 , both HTI-286 and hemiasterlin depolymerize preassembled microtubules at micromolar concentrations.

114 inding occurs between tau and the surface of preassembled microtubules, whereas irreversible binding

115 he effects of HTI-286 on soluble tubulin and preassembled microtubules.

116 isoform and caused disassembly when added to preassembled microtubules.

117 lexes, and coactivators are recruited to the preassembled MMP-9 promoter in a stepwise and coordinate

118 ity, we investigated the effect of Gadd45 on preassembled mononucleosomes.

119 Preassembled MukBEF was inert in DNA binding or reshapin

120 cruitment of additional Orai1 units to these preassembled multimers in order to form functional chann

121 of these spore coat glycoproteins exist as a preassembled multiprotein complex (the PsB multiprotein

122 r circular double-stranded DNA template with preassembled mushroom-shaped nanostructures having a pos

123 ts with calcium channel beta subunits in the preassembled N-type channel, thereby forming a nonconduc

124 late physiological H/ACA RNP assembly with a preassembled NAF1/dyskerin/NOP10/NHP2 scaffold purified

125 ions within the hysteresis loop, addition of preassembled nanofiber seeds leads to seeded polymerizat

126 In this study, we test whether the preassembled nature of the SCT makes them effective for

127 ce resonance energy transfer to characterize preassembled neuronal SNARE complexes consisting of synt

128 In our implementation, preassembled NGS contigs are used to derive the compact

129 K(+)-dependent conformational change of the preassembled NLRP3-inactive inflammasome during cell swe

130 gs suppress by releasing exosomes that carry preassembled NOX2 membrane clusters and are taken up by

131 During the assembly of alphaviruses, a preassembled nucleocapsid buds through the cell plasma m

132 rotein via a cytoplasmic endodomain with the preassembled nucleocapsid.

133 ase of H4), in activating transcription from preassembled nucleosomal array templates in vitro.

134 H4 (NuA4) stimulate HIV-1 transcription from preassembled nucleosomal templates in an acetyl CoA-depe

135 mes, activators must either invade a stable, preassembled nucleosome or preempt the formation of nucl

136 ot dissociate, H1 from its binding site on a preassembled nucleosome.

137 o 6- to 8-mer oligomers; condensation of the preassembled oligomers into large clusters containing hu

138 al step in this process is the transfer of a preassembled oligosaccharide to nascent proteins in the

139 for the maturation of [Fe-S] proteins can be preassembled on a molecular scaffold designated IscU.

140 enhancer function in which a TBP complex is preassembled on a promoter via localized recruitment and

141 d by rapid transfer of [4Fe-4S](2+) clusters preassembled on either the N- or C-terminal domains to t

142 Transcription complexes preassembled on immobilized templates were depleted of p

143 When the helicase was not preassembled on the DNA, a >65-nt long 5'-tail was requi

144 When the helicase was preassembled on the forked DNA before the start of unwin

145 erNAc-alpha-l-Fuc-beta-D-Glc-alpha-D-GalNAc, preassembled on undecaprenyl pyrophosphate (Und-P-P).

146 y they are decorated by a 'glycan', which is preassembled onto a membrane-anchored dolichol molecule

147 nonbent flanking sequence when a nucleosome preassembled onto this template was exposed to the drug

148 Cross-seeding peptide solutions with a preassembled peptide nanotube seed leads to domains of d

149 Using stepwise preassembled PICs, we show that hTR alpha targets either

150 blocked during assembly or dissociated from preassembled PICs.

151 onitored at a typical venous shear rate over preassembled platelet-associated prothrombinase neither

152 in a cell culture model based on delivery of preassembled polyGln aggregates into the cell nucleus.

153 s the regiospecific cyclization of a linear, preassembled polyketide chain catalyzed by aromatase/cyc

154 lity and can rely mostly on the transport of preassembled polymer.

155 that are consistent with the insertion of a preassembled pore complex into the bilayer.

156 ies have suggested that inactive R and G are preassembled (precoupled) as stable R-G complexes.

157 phage 29 packages its 19.3-kbp genome into a preassembled procapsid structure by using a transiently

158 the packaging of double-stranded DNA into a preassembled procapsid.

159 ontain molecular machines that pump DNA into preassembled procapsids, generating internal capsid pres

160 l molecular motors to translocate DNA into a preassembled prohead and compact the DNA to near crystal

161 ase (30-50%) in the elongational activity of preassembled, promoter-paused, pol II, and encompasses a

162 triggered by recruitment of SUMO ligases to preassembled protein complexes.

163 double-stranded DNA genomes package DNA into preassembled protein shells called procapsids.

164 Coscinodiscus wailesii, which suggests that preassembled protein-based templates might be general co

165 ration of proteolyzed prothrombin species by preassembled prothrombinase in phospholipid-coated glass

166 er reads for construction of highly accurate preassembled reads through a directed acyclic graph-base

167 These advances with versatile, preassembled reagents could greatly reduce the time and

168 ation is accompanied by a rearrangement of a preassembled receptor:G protein complex, ultimately lead

169 ow that many PRGs, in contrast to SRGs, have preassembled RNA polymerase II (Pol II) and positive his

170 may involve the subcellular translocation of preassembled signaling complexes from the plasma membran

171 -specific recombination was used to uncouple preassembled silent chromatin fragments from silencers.

172 ing factors can associate with and stabilize preassembled silent chromatin in non-S-phase cells demon

173 ramework (MOF) with a pcu-a topology using a preassembled soluble molecular octahedron has been reali

174 tenance, we used microneedle manipulation of preassembled spindles in Xenopus egg extracts.

175 I initiation and thereby controls the use of preassembled stable transcription complexes.

176 Complex I is put together from preassembled subcomplexes.

177 Coordinated transfer of a preassembled T complex is supported by these data and co

178 interacts directly and functionally with the preassembled t-SNARE complex.

179 ituted giant unilamellar vesicles containing preassembled t-SNARE proteins (syntaxin 1.SNAP-25), we d

180 he kinetic mechanism of dTTP hydrolysis by a preassembled T7 helicase hexamer in the absence of DNA.

181 used an approach involving the expression of preassembled tandem Orai1 multimers comprising different

182 netically defined a transition step in which preassembled Tat:P-TEFb complexes switch to TAR.

183 RNA polymerase II (RNAP II) recruitment to a preassembled TBP/TFIIB-containing scaffold and p53 stron

184 nhibition, we found that expression of these preassembled TCR beta-chains did not downregulate recomb

185 In this study, we demonstrate that a preassembled TCRbeta gene, but not a preassembled DbetaJ

186 However, addition of hTRas009 or hTRas010 to preassembled telomerase resulted in little or no inhibit

187 DNA as well as the recruitment of pol III to preassembled TFIIIB.DNA complexes.

188 Yet if the MuA-DNA complexes are preassembled, the first-order rate constants for both DN

189 Here, we used a library of preassembled three-finger zinc finger proteins (ZFPs) di

190 scription complexes, active genes migrate to preassembled transcription sites.

191 a substrate can be achieved by transferring preassembled ubiquitin chains from Ube2g2 to a lysine re

192 Purified preassembled vacuolar SNARE complex, when reconstituted

193 Expression of these preassembled VbetaDJbeta rearrangements inhibited endoge

194 Expression of either preassembled VbetaDJbetaC beta-chain accelerated thymocy

195 Presynaptic nerve terminals are formed from preassembled vesicles that are delivered to the prospect

196 Providing Emu-deficient mice with a preassembled VL gene led not only to a larger immature B

197 We report fabrication of a 4 mm thick, preassembled whispering gallery mode (WGM) sensor that c