ライフサイエンスコーパス: preaxial

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1 The polydactyly of GCPS is commonly preaxial and that of PHS is typically central or postaxi

2 ent, normal limb buds downregulate Fgf4, the preaxial cells do not regulate, and a truncated anteropo

3 ng all Shh-expressing cells) is removed, the preaxial cells reform a normal-shaped talpid(2) limb bud

4 selectively antagonizes formation of 'true' preaxial condensations that branch from this main axis (

5 Preaxial dominance is a notable feature of limb regenera

6 regenerate the limb, and the contribution of preaxial dominance to limb regeneration is unclear.

7 st digits to form are the two most anterior (preaxial dominance).

8 regeneration and may also be involved in the preaxial patterning during limb development.

9 Here we show that preaxial polarity in limb development was present in var

10 retained regenerative capacities as well as preaxial polarity in limb development.

11 salamanders are unique in showing a reversed preaxial polarity in patterning of the skeletal elements

12 Preaxial polydactyly (PPD) is a common limb-associated b

13 hh expression in the anterior limb bud and a preaxial polydactyly (PPD) skeletal phenotype.

14 efine a pathogenetic mechanism that leads to preaxial polydactyly (PPD).

15 nd Rim4; [1] [2] [3] [4] [5]) have in common preaxial polydactyly and longbone abnormalities.

16 expression of sonic hedgehog, with resulting preaxial polydactyly and mirror image duplications of po

17 urring mouse mutations with the phenotype of preaxial polydactyly exhibit ectopic Shh expression at t

18 activation of Sox9 in the digit 1 field and preaxial polydactyly in a Gli1- and Gli3-dependent manne

19 The mouse doublefoot (Dbf) mutant exhibits preaxial polydactyly in association with craniofacial de

20 This result suggests that Lmbr1 may underlie preaxial polydactyly in both mice and humans.

21 The major locus for dominant preaxial polydactyly in humans has been mapped to 7q36.

22 The mutant displayed preaxial polydactyly in the hindlimbs of heterozygous em

23 r-ectopic expression of SHH and induction of preaxial polydactyly is induced secondary to increased S

24 Our data indicates that in Dorking chickens, preaxial polydactyly is initiated independent of Shh.

25 is of the corpus callosum, tibial hemimelia, preaxial polydactyly of the feet, and intellectual disab

26 r the polydactyly ems (Pde) mutation display preaxial polydactyly of the hindlimbs, and homozygous sy

27 niofacial malformations, microphthalmia, and preaxial polydactyly of the right hindlimb.

28 reduced, limb skeletal defects progress from preaxial polydactyly to girdle reduction combined with h

29 nd resulting limb abnormalities that include preaxial polydactyly with duplication of posterior skele

30 efective digit patterning including hindlimb preaxial polydactyly with posterior digit transformation

31 In the hindlimb, preaxial polydactyly with variable expressivity was seen

32 we show that the chromosome 7q36 associated preaxial polydactyly, a frequently observed congenital l

33 contrast, loss of anterior T-box3 results in preaxial polydactyly, as seen with dysfunction of primar

34 nal cord, as well as neural tube defects and preaxial polydactyly, consistent with increased Shh sign

35 The congenital abnormality preaxial polydactyly, extra digits, is an example of thi

36 Another malformation, preaxial polydactyly, was exclusively seen in heterozygo

37 hemimelia, developmental hip dysplasia, and preaxial polydactyly, were also present in some family m

38 as acd/acd, p53(-/-) double mutants exhibit preaxial polydactyly.

39 e anterior margin in many mutants exhibiting preaxial polydactyly.

40 gene have multiple abnormalities, including preaxial polydactyly.

41 The hindlimbs of Dorkings form a preaxial supernumerary digit.

42 We show that preaxial talpid(2) limb bud mesoderm has polarizing acti

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