ライフサイエンスコーパス: prebiotic

1 ormula and other food ingredients containing prebiotics.

2 ow we can manipulate them through the use of prebiotics.

3 sing nondigestible food ingredients, such as prebiotics.

4 ny safety assessment of novel probiotics and prebiotics.

5 rincipal among these is that they may act as prebiotics.

6 rstanding of the beneficial effects of these prebiotics.

7 nger lasting than with other lower molecular prebiotics.

8 a good tool for the production of selective prebiotics.

9 itionally, the novel compound presented high prebiotic activities as ascertained in the presence of l

10 The level of the prebiotic activity is related to the availability of bet

11 as to isolate, characterize and evaluate the prebiotic activity of inulin and FOS from S. rebaudiana

12 xidant activity, antihypertensive effect and prebiotic activity of Maillard reaction products (MRPs)

13 The prebiotic activity of MOS was evaluated in vitro using t

14 Potential prebiotic activity was observed in all extracts, some in

15 e bioactive activity of the extracts, namely prebiotic activity, previously demonstrated.

16 Although inulin showed prebiotic activity, we were unable to show an increase i

17 rding short-chain fatty acid concentrations, prebiotic administration increased cecal acetate and pro

18 rate that diamidophosphate (DAP)-a plausible prebiotic agent produced from trimetaphosphate-efficient

19 ecular weight polysaccharides may be used as prebiotic agents to prevent gut dysbiosis and obesity-re

20 nflammatory effect with synbiotics than with prebiotics alone.

21 syntheses identifies a consensus set of 10 "prebiotic" alpha-amino acids.

22 ses the supplementation of edible films with prebiotics ameliorated the storage stability of L. rhamn

23 essential molecule as a nitrogen source for prebiotic amino acid syntheses such as the Strecker reac

24 of 12 or 13 amino acids and a percentage of prebiotic amino acids approaching 80%.

25 The results suggest that the prebiotic amino acids do comprise a foldable set within

26 m chemistry of all proteinogenic and various prebiotic amino acids.

27 Thus, aggregates of a prebiotic amphiphile bind certain heterocyclic bases and

28 sibility that aggregates of decanoic acid, a prebiotic amphiphile, interact with the bases and sugar

29 s present in acai (Euterpe oleracea) provide prebiotic and anti-genotoxic benefits in the colon.

30 sented dehydration reactions are relevant to prebiotic and green chemistry in alternative solvents.

31 models have shown some promising results for prebiotic and probiotic strategies as prophylaxis or tre

32 Lactulose is a well-known prebiotic and supports the alleviation of digestive diso

33 Eight studies compared prebiotic and synbiotic supplementation, 2 of which repo

34 rt the systemic anti-inflammatory effects of prebiotic and synbiotic supplementation.

35 Supplementation with prebiotics and black currant seed oil (gamma-linolenic a

36 igosaccharides (POS) have been considered as prebiotics and for the protection of humans from Stx.

37 ndeed, animal and human studies suggest that prebiotics and probiotics may have therapeutic roles in

38 Gut microbiota modification with specific prebiotics and probiotics might offer a novel and cost-e

39 Synbiotics, a mixture of prebiotics and probiotics, have been used for the preven

40 measures in addition to human milk, such as prebiotics and probiotics, to the management of high-ris

41 ood preservatives, stabilizers, supplements, prebiotics and quality enhancers) of PoP and PoPx compon

42 alter the gut microbial composition include prebiotics and resistant starches.

43 outcomes in studies examining the effect of prebiotics and synbiotics on systemic inflammation.

44 , such as targeted therapeutics, probiotics, prebiotics and synbiotics, to prevent perturbations in t

45 d the association between the consumption of prebiotics and the incidence of overweight or obesity.

46 of synbiotics (combination of probiotics and prebiotics) and must have included an assessment of AD d

47 ted carbohydrates, such as dietary fibre and prebiotics, and can mediate the interaction between the

48 ted carbohydrates, such as dietary fibre and prebiotics, and can mediate the interaction between the

49 This review examines the effect of SCFAs, prebiotics, and pre- and probiotic combinations (synbiot

50 ropose that a new generation of antibiotics, prebiotics, and probiotics coupled with novel, systems b

51 ta management models for testing probiotics, prebiotics, and synbiotics have been developed.

52 Recently, the effectiveness of probiotics, prebiotics, and synbiotics in reducing postoperative com

53 ASE, International Journal of Probiotics and Prebiotics, and The Cochrane Library databases for rando

54 her- and ester-containing alkyl molecules of prebiotic appeal and never detected in meteorites before

55 The usual target microorganisms for prebiotic approaches are bifidobacteria.

56 dyslipidemia in mice, and treatment with the prebiotic arabino-xylo-oligosaccharide, which reduced se

57 che, stability, and resilience and yielded a prebiotic (arabinoxylan) that allowed targeted manipulat

58 Prebiotics are dietary ingredients, usually oligosacchar

59 reat number of infant formulas enriched with prebiotics are disposal in the market, however there are

60 Prebiotics are non-digestible food ingredients that have

61 Prebiotics are selectively fermented by the gastrointest

62 Other candidate prebiotics are under investigation.

63 The in vitro prebiotic assay of these molecules indicates a strain sp

64 apparent chemical simplicity has made their prebiotic availability assumed, however, although the ki

65 Human-milk oligosaccharides can serve as prebiotics because the nondigestible oligosaccharides pr

66 icrobiota in humans, which suggests possible prebiotic benefits associated with the inclusion of red

67 ments that make them potential hot spots for prebiotic biochemistry.

68 ecies lead to the production of ground-state prebiotic building blocks, principally HCN.

69 An evaluation of the formation of prebiotic carbohydrates during lactose hydrolysis has be

70 for optimism on this difficult problem: the prebiotic chemical inventory may not have been as nightm

71 reagents in generating diversity within the prebiotic chemical inventory.

72 as a possible hub in the complex network of prebiotic chemical reactions leading from simple precurs

73 l pH that would have been more favorable for prebiotic chemistry and microorganisms than those record

74 he pools of short RNA oligomers arising from prebiotic chemistry and non-enzymatic replication is unc

75 nabolic reaction may indicate a link between prebiotic chemistry and the nature of the first metaboli

76 Carbonaceous meteorites contain clues to prebiotic chemistry because they preserve a record of so

77 Recent results in prebiotic chemistry implicate hydrogen cyanide (HCN) as

78 couple Earth's early evolution with complex prebiotic chemistry in these environments.

79 The prebiotic chemistry of formamide affords in a single and

80 s a potential transitional stage between the prebiotic chemistry of nucleotide synthesis and the cano

81 for the emergence of the RNA world from the prebiotic chemistry of the early earth.

82 role in metabolism and may have impacted the prebiotic chemistry that led to life.

83 eatly simplify models of the transition from prebiotic chemistry to simple biology.

84 ic RNA primer extension could illuminate how prebiotic chemistry transitioned to biology.

85 ield of inquiry and established the basis of prebiotic chemistry, a field of research that investigat

86 exploring potential nonterrestrial forms of prebiotic chemistry.

87 owever, places great demands on hypothetical prebiotic chemistry.

88 harge, giving birth to the research field of prebiotic chemistry.

89 have contributed as a starting material for prebiotic chemistry.

90 al compounds that could act as initiators of prebiotic chemistry.

91 onment, suggesting favorable environments to prebiotic chemistry.

92 move toward systems-level investigations of prebiotic chemistry.

93 conditions that make it possible, challenge prebiotic chemists.

94 charides and wheat dextrin) were selected as prebiotic co-components of gelatine based matrices plast

95 relin (P = 0.03) increased at 16 wk with the prebiotic compared with placebo.

96 ere we integrate these alternative models of prebiotic compartmentalization and develop a hybrid prot

97 Mechanisms of prebiotic compartmentalization are central to providing

98 t may have also played an important role for prebiotic compartmentalization in early life evolution w

99 sugar in RNA were selected from a mixture of prebiotic compounds and colocalized with such membranes,

100 ndent core metabolism producible from simple prebiotic compounds.

101 These results suggest that the prebiotic concentrations of urea in a geologically plaus

102 O, while intermittently adding the plausible prebiotic condensing reagent cyanamide.

103 reaction was catalyzed by cyanide ion under prebiotic conditions instead of its modern catalyst, thi

104 nzymatic polymerization of RNA strands under prebiotic conditions.

105 is converted to higher sugars under credible prebiotic conditions.

106 to glycolaldehyde, its dimer, under credible prebiotic conditions.

107 rigin and homochirality of amino acids under prebiotic conditions.

108 We evaluated the association between prebiotic consumption [fructans and galacto-oligosacchar

109 s is unclear.We set out to determine whether prebiotic consumption affects iron absorption from a mic

110 Higher prebiotic consumption was associated with lower risk of

111 However, a prebiotic conversion of these weakly activated monomers,

112 ta (GM) composition through the treatment of prebiotics could be a novel preventive measure against c

113 (HPP) and ultrasound (US) on the quality of prebiotic cranberry juice fortified with fructo-oligosac

114 essing has been proven satisfactory to treat prebiotic cranberry juice.

115 Novel probiotics and prebiotics designed to manipulate the gut microbiota for

116 ons between RNA and vesicle membranes on the prebiotic earth may have led to the emergence of primiti

117 The cyanide ion was probably not toxic on prebiotic earth, but only when the oxygen atmosphere dev

118 lts suggest that viscous environments on the prebiotic Earth, generated periodically by water evapora

119 ection may have been robust processes on the prebiotic Earth, if other nucleobases preceded those of

120 ccepted that amino acids were present on the prebiotic Earth, the mechanism by which alpha-amino acid

121 the problem of organic phosphorylation on a prebiotic Earth.

122 of inorganic NPs including those existing on prebiotic Earth.

123 lfur clusters could have been synthesized on prebiotic Earth.

124 The concept of prebiotic edible films as effective vehicles for encapsu

125 s is the first study reporting the potential prebiotic effect of jucara pulp; however, human studies

126 On the basis of the proven prebiotic effects of oligosaccharides in cow's milk form

127 We review probiotic and prebiotic effects on emotional, cognitive, systemic, and

128 Dietary oligosaccharide structures that have prebiotic effects similar to human-milk oligosaccharides

129 recent interest due to their antioxidant and prebiotic effects.

130 recent interest due to their antioxidant and prebiotic effects.

131 that several challenges associated with the prebiotic emergence of RNA, or pre-RNA polymers, may not

132 ng been considered a major limitation to the prebiotic emergence of RNA.

133 e suggests the existence of an RNA molecular prebiotic entity, called by us the "protoribosome," whic

134 The reactivity of these components in a prebiotic environment that supplied sources of chemical

135 From their common root in the ancient prebiotic environment, oxidoreductases have evolved into

136 related single-chain lipids available in the prebiotic environment.

137 ssembling the building blocks of life in the prebiotic era.

138 The prebiotic evolution therefore must have crossed this cri

139 pe necessarily comprises amphipaths, such as prebiotic fatty acids, to partition the two aqueous doma

140 We also observed that prebiotic feeding normalized A. muciniphila abundance, w

141 The consumption of prebiotics (fermentable and nondigestible carbohydrates)

142 This work indicates that HPMC is a potential prebiotic fiber that influences intestinal microbiota an

143 ts the use of nopal as a functional food and prebiotic for its ability to modify gut microbiota and t

144 ese discrepancies, we compared impact of one prebiotic formula on the same inoculated fecal microbiot

145 Chronic prebiotic FOS+GOS treatment exhibited both antidepressan

146 de fragments with suspected organoleptic and prebiotic function.

147 ant formula to mimic the molecular sizes and prebiotic functions of human milk oligosaccharides.

148 rku, Finland, were allocated to receive oral prebiotics (galacto-oligosaccharide and polydextrose mix

149 cine albumin (PSA) that were conjugated with prebiotic galactooligosaccharides (GOS) were synthesised

150 of the structural variation of dextrans and prebiotic GLOS.

151 hylaxis to galacto-oligosaccharides (GOS), a prebiotic, has been described in atopic patients followi

152 of studies of probiotics used together with prebiotics have been overall negative.

153 Prebiotics have been shown to improve satiety in adults

154 Additionally, prebiotics have established benefits for glucose control

155 The same prebiotics have produced inconsistent effects on microbi

156 Here we show that two plausible prebiotic heterocycles, melamine and barbituric acid, fo

157 OTUs within the same genus responded to the prebiotic in opposite ways.

158 urpose, we studied the preventive effects of prebiotics in Balb/c mothers during pregnancy and breast

159 rces of specific oligosaccharides for use as prebiotics in supplements or food products.

160 Whether consumption of prebiotics increases iron absorption in infants is uncle

161 Mechanisms related to prebiotic-induced changes in gut microbiota (shot-gun se

162 umerous human feeding studies have shown the prebiotic influences that galactans and fructans can exe

163 eta-d-glucan had good potential for use as a prebiotic ingredient in food, as well as medicinal and p

164 igosaccharides from lactulose can be used as prebiotic ingredients in a wide range of functional food

165 mpleted by caregivers.Compared with placebo, prebiotic intake resulted in significantly higher feelin

166 a different family of molecules of potential prebiotic interest.

167 ocussing on the search for organic matter of prebiotic interest.

168 lyceraldehyde--two species considered as key prebiotic intermediates in the first steps toward the sy

169 steviol glycoside, Luo Han Kuo), and natural prebiotic (inulin).

170 Here, the effects of a dietary prebiotic, inulin (50 mg/g diet), and probiotic, Bfidoba

171 the food delivery vehicle on the efficacy of prebiotics is an area that has been hardly investigated.

172 biota-independent immune modulation by these prebiotics is provided.

173 acidophilus counts, and functionality of the prebiotics L. acidophilus), physicochemical (pH, proteol

174 Homochirality is explained by origin of prebiotic life in one hemisphere of earth and its evolut

175 ded by the direction of magnetic field where prebiotic life originated on Archaean earth.

176 and nitrate (beet juice), which may induce a prebiotic-like effect.

177 hydroxide concentration are atypical in the prebiotic literature, there is evidence for natural, abi

178 ty to favorably modulate the gut microbiota, prebiotics may provide an inexpensive yet effective diet

179 in the first year of life with immunoactive prebiotics might have a preventive role against early de

180 mediating surface-catalyzed synthesis in the prebiotic milieu.

181 Prebiotics modified specific gene expression in the hipp

182 rolyzed protein infant formula with specific prebiotics modulated the gut microbiota closer to that o

183 is one of the important compounds from which prebiotic molecules can be synthesized, provided that it

184 barrierless reactions are capable of forming prebiotic molecules such as nitrogen substituted PAHs (N

185 Meinert et al reported the formation of prebiotic molecules, including ribose, in an interstella

186 that could then be readily incorporated into prebiotic molecules.

187 the inner Solar System, and the formation of prebiotic molecules.

188 ydrocarbon radicals lead to the formation of prebiotic N-containing organic molecules.

189 The prebiotic nature of human milk oligosaccharides (HMOs) a

190 tween nitrogen bearing acyclic molecules and prebiotic nucleobases along with vitamins found in meteo

191 -dihydroxypropyl)adenine (DHPA), a plausibly prebiotic nucleoside analog of adenosine.

192 Further, by choosing plausibly prebiotic nucleosides, insights may be provided into how

193 implications for RNA oligomer synthesis from prebiotic nucleotide pools.

194 obust synthesis of phosphoenol pyruvate from prebiotic nucleotide precursors, glycolaldehyde and glyc

195 Understanding prebiotic nucleotide synthesis is a long standing challe

196 kinawite, a catalytic Fe(Ni)S mineral, under prebiotic ocean conditions.

197 Negative controls (no prebiotic) of both systems showed significant shifts in

198 ebo-controlled, randomized trial, we found a prebiotic (OI) to selectively alter the intestinal micro

199 infant formulas (IFs) are supplemented with prebiotic oligosaccharides, such as galactooligosacchari

200 ro evaluation of the modulatory effects of a prebiotic on microbiota, it is necessary to use both oli

201 zed controlled trial to study the effects of prebiotics on body composition, markers of inflammation,

202 udies have suggested roles of probiotics and prebiotics on body weight management and intestinal func

203 We hypothesized that early prebiotic or probiotic supplementation would reduce the

204 to manipulate the intestinal microbiota with prebiotics or other agents to prevent or treat obesity.

205 ood potential source of AX for production of prebiotics or other novel products.

206 There is no evidence to support the use of prebiotics or probiotics for food allergy prevention.

207 dy beetle or stink bugs), in the diet (e.g., prebiotics or wheat isolates), or because of the spread

208 pigtail macaques with ARVs, probiotics, and prebiotics or with ARVs alone.

209 h additional active ingredients (probiotics, prebiotics, or both) (LPFA) and breastfed infants.

210 gible if they examined the effects of SCFAs, prebiotics, or synbiotics; were delivered orally, intrav

211 m the reaction of reduced P species with the prebiotic organic milieu on the early Earth.

212 -appreciated obstacle for proposed models of prebiotic organophosphate formation.

213 e environmental conditions, and hence on its prebiotic origin.

214 late, merits consideration of an alternative prebiotic pathway for providing constituents of the citr

215 that layered hydroxides could have played in prebiotic peptide formation.

216 Prebiotic phosphorylation of (pre)biological substrates

217 This plausible prebiotic phosphorylation process under similar reaction

218 of sauconite, a model for clay minerals, to prebiotic photochemistry.

219 se and while there is mounting evidence that prebiotics play a role in colorectal cancer prevention,

220 with the notion that dietary factors such as prebiotics play important roles in the growth of intesti

221 d oligosaccharides from H. suaveolens have a prebiotic potential characterized by a delayed but long

222 The prebiotic potential of this mixture was demonstrated upo

223 res and arabinose-rich POS2 had the greatest prebiotic potential.

224 xo-purine nucleotides starting from a common prebiotic precursor that yields the beta-ribo-stereochem

225 of simple compartmentalized systems, such as prebiotic precursors of cells and cell-inspired artifici

226 ure, in view of a foreseeable use as a novel prebiotic preparation.

227 Centered particularly on the use of prebiotics, probiotic bacteria, and bacterial lysates in

228 l trials have identified a limited number of prebiotics, probiotic strains, and synbiotics that favor

229 f these conditions through administration of prebiotics, probiotics, and synbiotics.

230 jective symptoms after its manipulation with prebiotics, probiotics, or antibiotics.

231 It is thought that prebiotic processes were able to synthesize short random

232 For example, specific prebiotics promote favorable intestinal colonization, an

233 lactating mice with nondigestible GOS/inulin prebiotics promotes a long-term protective effect agains

234 PS from Laffan and Wonderful mesocarp showed prebiotic properties in vitro with Lactobacillus and Bif

235 ead, while the GLOS may have antistaling and prebiotic properties, depending on their structure.

236 ew source of oligosaccharides with potential prebiotic properties.

237 ts preserved the FOS content maintaining the prebiotic property of the juice.

238 ce of RTIs was detected in infants receiving prebiotics (rate ratio [RR], 0.24; 95% CI, 0.12-0.49; P

239 Here we report a one-pot model prebiotic reaction between a pyrimidine nucleobase (2,4,

240 mamide (HCONH(2)) is a heavily studied model prebiotic reaction that has offered valuable insights in

241 However, compatible prebiotic reactions for the synthesis of complementary (

242 While prebiotic reactions from the rTCA cycle were accomplishe

243 However, the formation of RNA by plausible prebiotic reactions remains problematic.

244 ination of ester and amide linkages-in model prebiotic reactions that are driven by wet-cool/dry-hot

245 ight have been available on early Earth from prebiotic reactions, with the goal of making the model l

246 Meta-analyses indicated that prebiotics reduce C-reactive protein (CRP) [standardized

247 We identified prebiotic responders via redundancy analysis by includin

248 ate that just as 2-aminooxazole-an important prebiotic ribonucleotide precursor-is readily formed fro

249 n-enzymatic RNA synthesis and may have aided prebiotic RNA replication.

250 essential role in any clay mineral-catalyzed prebiotic RNA synthesis.

251 ing insight into the differences between the prebiotic RNA world and the present protein-dominated wo

252 cules, and the evolution of enzymes from the prebiotic, RNA-based world to the modern world.

253 emerged as a plausible structural element in prebiotic RNAs.

254 In this review, an overview of the prebiotic role of dietary oligosaccharides on the microb

255 embrane evolution through the provision of a prebiotic route for the synthesis of plausible membrane

256 s newly discovered chemistry thus suggests a prebiotic route from ribonucleoside-2',3'-cyclic phospha

257 , was found to be significantly lower in the prebiotic (RR, 0.31; 95% CI, 0.14-0.66; P = .003) and pr

258 utline plausible exogenous high-energy-based prebiotic scenarios and their possible boundary conditio

259 y and, possibly, two different and competing prebiotic scenarios.

260 n essential unsolved question regarding this prebiotic set is whether it defines a "foldable set"--th

261 wledge base for studying the biochemical and prebiotic significance of RNA 2-5-linkages.

262 Prebiotic soluble fibers are fermented by beneficial bac

263 d specific molecules of life arose from the 'prebiotic soup' remains an unsolved problem.

264 valuated for their suitability to be used as prebiotic sources in a rice noodle product.

265 Fourteen of 29 prebiotic studies and 13 of 26 synbiotic studies reporte

266 Nurturing a beneficial gut microbiome with prebiotics, such as fructo-oligosaccharides (FOS) and ga

267 043).Independent of other lifestyle changes, prebiotic supplementation in children with overweight an

268 ldren are limited.We examined the effects of prebiotic supplementation on appetite control and energy

269 Compared with placebo, prebiotic supplementation significantly reduced energy i

270 ent-to-treat analysis, there was a trend for prebiotic supplementation to reduce BMI z score to a gre

271 Our objective is to evaluate the effects of prebiotic supplementation, adjunct to those achieved wit

272 NAFLD will be randomized to either a 16 g/d prebiotic supplemented group or isocaloric placebo group

273 ore holistic approach when using probiotics, prebiotics, synbiotics, antibiotics, and anthelmintics,

274 Moreover, the prebiotic syntheses of pyrimidine and purine nucleotides

275 is review, I cover the continued advances in prebiotic syntheses that Miller's pioneering work has in

276 Some of the alternatives to the Miller-based prebiotic synthesis and the "primordial soup" paradigm a

277 We propose a novel pathway for the prebiotic synthesis of 2'-deoxynucleotides.

278 rsite was, hence, a plausible reagent in the prebiotic synthesis of phosphorylated biomolecules and w

279 The most plausible prebiotic synthesis of sugars involves photoreduction of

280 oxazoline as a potential intermediate in the prebiotic synthesis of the pyrimidine nucleotides with r

281 trol might have made the initial pathways to prebiotic systems evolution more intricate, but were sur

282 Given that prebiotics target multiple metabolic impairments associa

283 It also catalyzes the synthesis of FOS, prebiotics that stimulate the growth of beneficial bacte

284 ns (ginsenoside-Rb3 and ginsenoside-Rd) - as prebiotics - that effectively reinstated the dysbiotic-g

285 s obtained by GC-FID for products containing prebiotics, the content of FOS, GOS and GOS/FOS was in t

286 chobiotics be expanded beyond probiotics and prebiotics to include other means of influencing the mic

287 Also, the addition of prebiotics to MNPs is a promising approach to mitigate t

288 is bacterial fermentation of "indigestible" prebiotics to short-chain fatty acids (SCFAs), which in

289 owever, little is known about the ability of prebiotics to specifically modify gut microbiota in chil

290 e data strongly suggest a beneficial role of prebiotic treatment for stress-related behaviors.

291 Here we tested whether chronic prebiotic treatment modifies behavior across domains rel

292 ossible beneficial commensals, confirmed the prebiotic value of these xylooligosaccharides.

293 verning introduction of novel probiotics and prebiotics vary by geographical region.

294 an experimental study on the permeability of prebiotic vesicle membranes composed of binary lipid mix

295 f synthetic protocell biology has shown that prebiotic vesicles are able to 'steal' lipids from each

296 The addition of prebiotics was associated with a more compact and unifor

297 spring from mothers that received GOS/inulin prebiotics were protected against food allergies and dis

298 We expand this definition to encompass prebiotics, which enhance the growth of beneficial gut b

299 n-oligosaccharides (AXOS) are a new class of prebiotics with promising health-promoting characteristi

300 to contemplate in the chemical chaos of the prebiotic world.