ライフサイエンスコーパス: precapillary

1 /-17.3 mm Hg; P=0.015) but not in those with precapillary (49.0+/-12.6 versus 51.6+/-14.3; P=0.36).

2 evere pulmonary hypertension associated with precapillary arterial occlusion by proliferating endothe

3 ypertension (PH) is characterized by complex precapillary arteriolar lesions, which contain phenotypi

4 In the precapillary arteriole, 1 myocyte covers a approximately

5 In the precapillary arteriole, Ca signals arise solely from Ca

6 dothelial cell-proliferative lesions of lung precapillary arterioles composed of clusters of phenotyp

7 signaling and coordination of contraction in precapillary arterioles in ureter and vas deferens.

8 ut 50% of total oxygen uptake takes place in precapillary arterioles of less than 30 mum in diameter

9 In pulmonary hypertension the loss of precapillary arterioles results from vascular injury cau

10 anthosis and a preferential occlusion of the precapillary arterioles with infiltration of neutrophils

11 Blood flow is assumed to be regulated by precapillary arterioles, because capillaries lack smooth

12 m vessels near metabolically active cells to precapillary arterioles, suggesting that blood flow cont

13 d ECs from contracting and reorganizing into precapillary cords within collagen gels.

14 Precapillary gas exchange contributes importantly to blo

15 nd-diastolic pressure, >15 mm Hg; n=269) and precapillary groups (left ventricular end-diastolic pres

16 r 1-year mortality rate was observed in both precapillary (hazard ratio, 2.30; 95% confidence interva

17 intraarterially delivered MSCs entrap at the precapillary level because of their large size, with a s

18 and interrupt flow during first pass at the precapillary level, resulting in decreased flow in the f

19 in TRPC1(-/-) animals as well as in isolated precapillary murine PASMC after TRPC1 knockdown by TRPC1

20 functional features that do not overlap with precapillary or arteriolar smooth muscle actin-expressin

21 In chronic hypoxic mice, precapillary oxygenation was significantly attenuated as

22 scular resistance defines combined post- and precapillary PH (Cpc-PH).

23 We prospectively included 17 patients with precapillary PH and 7 control subjects without PH who pe

24 Dasatinib may induce severe precapillary PH fulfilling the criteria of pulmonary art

25 Isolated cases of precapillary PH have been reported in patients who have

26 t diagnosis, patients had moderate to severe precapillary PH with functional and hemodynamic impairme

27 roportional to the physiological severity of precapillary PH, demonstrating its prognostic and clinic

28 PC1 and TRPC6 are predominantly expressed in precapillary pulmonary arterial smooth muscle cells (PAS

29 Precapillary pulmonary arteries are affected by medial h

30 k exposure) results in obliteration of small precapillary pulmonary arteries by proliferating endothe

31 in human severe pulmonary hypertension, the precapillary pulmonary arteries show occlusion by prolif

32 nsion (PAH) is an obstructive disease of the precapillary pulmonary arteries.

33 cular smooth muscle hypertrophy of the small precapillary pulmonary arteries.

34 characterized by vascular remodeling in the precapillary pulmonary arterioles.

35 patients (11%) met hemodynamic criteria for precapillary pulmonary hypertension (mean pulmonary arte

36 Precapillary pulmonary hypertension (PH) is an important

37 major predictor of outcomes in patients with precapillary pulmonary hypertension because of pulmonary

38 measures in a large cohort of patients with precapillary pulmonary hypertension before and after ini

39 sion and present in all 14 of the identified precapillary pulmonary hypertension cases among the comb

40 trait locus, rs10857560, was associated with precapillary pulmonary hypertension defined as mean pulm

41 ely in a cohort of consecutive patients with precapillary pulmonary hypertension referred between 200

42 related pulmonary hypertension patients have precapillary pulmonary hypertension with potential etiol

43 ion quantitative trait locus associated with precapillary pulmonary hypertension.

44 ower pulmonary pressure in SCD patients with precapillary pulmonary hypertension.

45 hort comprised 777 patients (514 women) with precapillary pulmonary hypertension.

46 These data support the notion that precapillary resistance is influenced by signals generat

47 g that both mean arterial blood pressure and precapillary resistance remained constant.

48 , ANP causes greater increases in post- than precapillary resistance, thus increasing intrasplenic ca

49 sure steps is associated with a reduction in precapillary resistance.

50 Pulmonary arteriolar (precapillary) resistance is elevated.

51 ally and functionally distinct from adjacent precapillary smooth muscle cells (SMCs).

52 elial cells to form solid cords that imitate precapillary structures found during angiogenesis.

53 efenses against heat are sweating and active precapillary vasodilation; the primary autonomic defense

54 hypertension have a PGIS deficiency of their precapillary vessels, but the importance of this deficie