ライフサイエンスコーパス: precise

1 cases) were in a similar direction, but less precise.

2 estimate and is one order of magnitude more precise.

3 ing event in its 2015 outburst, we present a precise 461 +/- 12 gauss magnetic field measurement in t

4 Using 2Phatal, we achieve precise ablation of distinct populations of neurons, gli

5 identify strategies by which animals execute precise actions using sparse motor networks, we imaged t

6 ially targetable, repeatable and temporarily precise activation of deep-brain circuits without the ne

7 f behaving macaque monkeys during temporally precise activation of vestibular afferents.

8 omechanical AFM procedure (SNAP) ensures the precise adjustment of the AFM optical lever system, a pr

9 Here, we present the most detailed and precise age model for European loess dust deposits to da

10 Europe around 0.96-0.781 Ma is possible, the precise age of the classical site at SZ is still controv

11 ely poor chronological control has precluded precise alignment of ice, atmospheric and marine records

12 or Cu into hollow Au nanoclusters, creating precise alloy nanoparticles atom-by-atom.

13 The precise amino acid sequence and prenyl group define a co

14 First, we used Openspritzer to deliver precise amounts of reagents to hippocampal neurons to el

15 ion, there is little consensus regarding its precise anatomic definition.

16 l microbiology laboratory (CML) provide more-precise and -sensitive tests, altering HAI detection in

17 ons for insolation, which will enable a more precise and accurate geological timescale to be produced

18 n-specific signals isolated in CV-PACs allow precise and accurate positioning of Hg-based SECM probes

19 The methods were precise and accurate when applied to the standard soluti

20 The method is rapid, precise and accurate, and it will represent a fundamenta

21 Sequence recovery was precise and admixtures of as low as 1% could be identifi

22 y continuous total internal reflection, in a precise and controlled manner to exceptional points.

23 both examine cellular processes and achieve precise and dynamic control of cellular phenotype.

24 Using the chick as a model, we found a precise and dynamic expression pattern of fibroblast gro

25 In summary, SNGD promotes precise and efficient gene editing and may be a promisin

26 automated cantilever-based method for highly precise and sensitive measurements of microliter sample

27 gle-stranded DNA repair templates results in precise and targeted DNA replacement with as much as app

28 tes conserved structural organization, not a precise array of heptad motifs, as important to CTD func

29 s material is a promising approach to create precise arrays of qubits.

30 However, the precise assessment of in vivo relevance in different dis

31 g and computational modeling, we resolve the precise atomic structure of metal-oxo species deposited

32 of photosystem II allows us to identify the precise atomic-level differences between organisms in th

33 a combination of manual curation and highly precise automated tools, aiming to have the same accurac

34 programmable "base editing" system to induce precise base conversion with high efficiency in zebrafis

35 ks to the capacity, at the larval stage, for precise behavioral measurements, genetic manipulations,

36 but it poses challenges for determining the precise binding interactions and downstream effects of d

37 derly is a risk factor for dementia, but the precise biological basis remains unknown, hampering the

38 mization and inference but also to implement precise Boolean functions in an inverted mode.

39 also outperformed two existing algorithms on precise breakpoint prediction, which is clinically impor

40 based on SBC responses were temporally more precise, but the match between acoustic and represented

41 The precise cause of ET is unknown, however pathological osc

42 Although the precise cause remains unknown, space flight-associated n

43 These results raised questions regarding the precise cellular location of myomaker function and mecha

44 ever control might improve outcome, and more-precise characterization of CSF leukocytes could guide p

45 udies such as intercluster reactions forming precise clusters.

46 nction comprising a redox-active, atomically precise cobalt chalcogenide cluster wired between two na

47 consensus-based reporting system that offers precise composite scores, accurate routine diagnostics,

48 er in already GC-poor regions, and using our precise context-dependent mutation rates to predict long

49 pe affects consolidation and/or retrieval of precise contextual and spatial memories.

50 rtant role in the long-term consolidation of precise contextual memories and constrains generalized f

51 inhibition is not critical for retrieval of precise contextual memory, but rather has an important r

52 andidates for playing such a role, yet their precise contribution has remained elusive.

53 However, the precise contribution of apoptosis to GC biology and sele

54 gents of key ecological processes, but their precise contributions compared with other organisms have

55 We therefore set out to determine the precise contributions of Esco1 and Esco2 to cohesion in

56 Precise control of alloying sites has long been a challe

57 The precise control of an ion channel gate by environmental

58 These findings reveal a surprisingly precise control of attention and its involvement in fine

59 Precise control of cell death is crucial for tissue home

60 sential to optimize epitaxial growth for the precise control of nanowire geometry and density.

61 Modulation and precise control of porosity of metal-organic frameworks

62 a flexible disordered activation loop yields precise control of signal transduction.

63 tions of femtomolar PtCl6(2-), which allowed precise control of the arrival of ions and thus the plat

64 Precise control of the cell cycle allows for timely repa

65 Precise control of the selective growth of heterostructu

66 The fast and precise control of the STEM probe is, however, challengi

67 During development and homeostasis, precise control of Wnt/beta-catenin signaling is in part

68 The tunable optical properties by precise control of WS2 layers could empower a great deal

69 itaxial growth in aqueous solvent, achieving precise control over 1D nanostructures in water, an esse

70 ith crystallization-driven self-assembly for precise control over micelle formation to prepare a new

71 it distinct features such as (i) an easy and precise control over the particle size and shape, (ii) a

72 ensional system, whose manipulation requires precise control over the whole system.

73 With most applications requiring precise control over this surface modification, characte

74 The dBFP provides precise controls and quantitative readouts in both mecha

75 Regulation of blood glucose requires precise coordination between different endocrine systems

76 addition, cortical pathways that mediate the precise coordination between hemispheres required for so

77 Precise coordination of synaptic connections ensures pro

78 r-induced breakdown spectroscopy allowed the precise copper determination (coefficient of variation =

79 tation in human preimplantation embryos with precise CRISPR-Cas9-based targeting accuracy and high ho

80 atures of HIV gene diversification can allow precise cross-sectional surveillance with a desirable te

81 INTERPRETATION: The PRECISE-DAPT score is a simple five-item risk score, whi

82 nterpretation is complicated by increasingly precise data obtained via multicollector mass spectromet

83 TE) often is considered, but clinicians need precise data on cancer prevalence, risk factors, and the

84 Here we use precise data on over 50,000 Drosophilid fly wings to dem

85 Precise dating of diamond growth is required to understa

86 However, insufficient resolution precluded a precise definition of the aNT-d interface.

87 Analytic advances are enabling more precise definitions of the molecular composition of key

88 emonstrated that an efficient fabrication of precise dental restoration is achievable by use of the p

89 These results provide a temporally precise description of the transformation from low- to h

90 DOMAIN (IDD) transcription factors, although precise details of these specific interactions and actio

91 age and algorithms promise to facilitate the precise determination and description of lectin and glyc

92 concurrent transcriptional changes to ensure precise developmental transitions during cellular differ

93 progressive IRD subtypes and to establish a precise diagnosis in a timely fashion.

94 ected pretransplant cohorts, but use of more precise diagnostic methods is needed to better define ep

95 ds and provides new perspectives on electron-precise dianionic diboranes featuring two-center-two-ele

96 these components may aid in supporting more precise differential diagnosis in such heterogeneous dis

97 a homogeneous antibody-drug conjugate with a precise drug-to-antibody ratio of 2.

98 division is a complex process that requires precise duplication of genetic material.

99 as been detected in periodontal lesions, the precise effect of collagen glycation on gingival connect

100 gans, the ribbon synapse is required for the precise encoding of a wide range of complex stimuli.

101 e influences the spontaneous spiking and the precise encoding of stimulus onset in afferent neurons.S

102 Atomically precise engineering of the position of molecular adsorba

103 lity, yet many predictors of outcome are not precise enough to guide initial clinical decision-making

104 RETATION: By applying a novel approach, more precise estimates of life-years lost were obtained.

105 Precise estimates of neonatal sepsis burden vary by sett

106 te the day/night patterns and determine more precise estimates of the cosinor parameters.

107 mple sizes, and power was limited to provide precise estimates.

108 provide higher taxonomic resolution and more precise estimation of abundance.

109 ad counts can be leveraged to achieve a more precise estimation of the mean and variance of measureme

110 by the interaction symmetry rather than the precise experimental parameters, and in that it occurs u

111 ide lymphocyte differentiation depend on the precise expression and timing of transcription factors (

112 In the present work, we have demonstrated precise external control of such networks by activating

113 receptors in consolidation or retrieval of a precise fear memory.

114 Finally, we propose that precise fine-tuning of conduction along already-myelinat

115 evelopment of Plasmodium falciparum, but its precise function and substrates remain largely unknown.

116 for normal protein N-glycosylation, but its precise function is not known.

117 de, the next pressing challenge is to assign precise functions to each CRM, i.e. to determine the spa

118 oters is a critical mechanism for specifying precise gene activation.

119 We developed a strategy for precise gene editing that does not generate DSBs.

120 Understanding the precise genetic consequences of such reductions, however

121 unctions can be further dissected, we need a precise genetic null mutant to definitively map its amor

122 e of the acoustic-transfection technique for precise genome editing using CRISPR-Cas9.

123 careful sub-typing of cases may provide more precise genomic signals.

124 l- or oxa-lanthionine rings confirm that the precise geometry of these rings is essential for this sy

125 nd electronic characterization of atomically precise GNR heterojunctions prepared through late-stage

126 Our precise, high-throughput technique revealed stable betwe

127 This enhancement enables precise identification and quantification of BAT mass no

128 adata and chemical substructure search allow precise identification of desired compounds or functiona

129 Objective and precise identification of individuals at risk, ways of m

130 g of tissue with immunofluorescence allowing precise identification of small structures, to quantitat

131 However, the precise identification of the endocardial precursors and

132 ned by our relative lack of knowledge of its precise in vivo mode of action.

133 This in turn enables precise in-situ alignment detection, for the first pract

134 suggests that the transmission of temporally precise information is degraded at the endbulb during AR

135 This provides temporally precise information over a heterogeneous population in p

136 over time, evolving and tailoring elegantly precise inhibitors of the rate-limiting steps within the

137 rely on fast sensory encoding for rapid and precise initiation of startle responses.

138 at exposure research provides more valid and precise insights into how often people encounter heat co

139 nscription of individual genes; however, the precise interactions of these events are complex and lar

140 een improved and expanded by integrating the precise Islander method for pre-computed genomes, as wel

141 However, the lack of precise knowledge about the shapes, growth and dipole pa

142 As new applications for omalizumab demand precise knowledge of the onset of effects, the objective

143 hemicals, and the analysis outcome relies on precise knowledge of the probe and analyte concentration

144 le orientation for optical access needed for precise laser surgery and high-resolution imaging.

145 Precise lineage trajectories and the cellular sources th

146 er of patients diagnosed with DCIS, making a precise localization of nonpalpable DCIS lesions even mo

147 s plays an important role in controlling the precise localization of these receptors at specific regi

148 of MUF-77, which places each component in a precise location to circumvent disorder.

149 Examples of precise loss of some exonic IES in the micronucleus and

150 r than opposed, adaptations that facilitated precise manipulation and tool use.

151 e PT-symmetry condition can be achieved by a precise manipulation of the interplay between the gain a

152 modifications into proteins in a benign and precise manner are highly sought-after in protein scienc

153 l plasticity by acting in a nonredundant and precise manner in the brain.

154 rapy for patients in a more personalized and precise manner.

155 sis varies with professional experience with precise manual tasks.

156 th and without amyloid deposition by a novel precise mass spectrometry method at the Washington Unive

157 However, the precise means by which p53 dynamically interacts with TF

158 Here we propose an efficient and precise measure for network comparison, which is based o

159 of an atom of antimatter represents the most precise measurement performed on an anti-atom.

160 At least in part, less accurate and precise measurements and less than full transparency in

161 It provides direct and precise measurements of the isotopic ratios delta(17)O a

162 me in addition to the difficulties of making precise measurements within a living tumor.

163 a consistent manner to obtain sensitive and precise measurements.

164 ceramics through grain boundary engineering, precise mechanical characterization of individual bounda

165 The precise mechanism by which the bacterial SRP receptor, F

166 the deregulation of energy homeostasis, the precise mechanism is poorly understood.

167 that LBH could modulate the cell cycle, the precise mechanism is unknown and its impact on inflammat

168 However, the precise mechanism of CIITA and MHC-II down-regulation is

169 Understanding the precise mechanism of NLRP3 activation by such a wide arr

170 regulate neutrophil activation; however, the precise mechanism of this process remains unclear.

171 to promote CNG and HCN channel opening, the precise mechanism underlying gating remains poorly under

172 Additional investigation to elucidate the precise mechanism underlying gene-length dependent chang

173 However, the precise mechanism underlying this synergy within NK cell

174 However, the precise mechanism(s) by which the COX/PGE2 pathway regul

175 However, its precise mechanism(s) of action remains unclear.

176 However, the precise mechanisms by which microglia alter the course o

177 ys that RAS controls are well known, but the precise mechanisms by which RAS proteins function are le

178 roRNA-200 (miR-200) family and ZEB1, but the precise mechanisms by which ZEB1-dependent EMT promotes

179 However, the precise mechanisms involved are unclear.

180 BI in HIV-infected individuals, although the precise mechanisms whereby HIV infection impedes success

181 NA secondary structures offers an effective, precise, medicine-based approach to directly impede tran

182 DNA is a remarkably precise medium for copying and storing biological inform

183 ows that mice spontaneously form a spatially precise memory of the location of shelter, which is laid

184 Atomically precise metal nanoclusters with tailored surface structu

185 In contrast, families of atomically precise metal oxide nanoparticles are currently lacking,

186 ive 3D analysis with dense sampling offers a precise methodology for showing effects of NAM treatment

187 ns of ultimate width, they are valuable atom-precise model systems for studying the properties of thi

188 rget sites requires spatially and temporally precise modulation of biochemical signals within growth

189 al transduction pathway could allow for more precise modulation of dopamine circuit function.

190 ating Brevican levels, experience introduces precise molecular and cellular modifications in PV+ cell

191 (PX) domain in complex with IncE define the precise molecular basis for these interactions.

192 ormed from the binary assembly of atomically precise molecular clusters, is a superatomic analogue of

193 d interkinetic nuclear migration, as well as precise molecular control via the non-canonical Wnt/plan

194 am of even awake, ambulatory rats, achieving precise molecular measurements at clinically relevant de

195 Expanded, regulate pathway activity, but the precise molecular mechanism by which they function is st

196 The precise molecular mechanism underlying the regulation of

197 n mammalian adult neurogenesis; however, the precise molecular mechanisms and critical functional pla

198 The precise molecular mechanisms of beta-adrenergic activati

199 py in adult slices was used to determine the precise molecular-events sequence responsible for the ra

200 rates visuovestibular inputs into temporally precise motor commands for the lateral rectus eye muscle

201 social experience are required to coordinate precise movements between pairs of larvae, therefore inc

202 pathway that produced genetic variants with precise mutations in promoters, genes, and terminators,

203 However, the precise nature and relative contributions of these featu

204 ainst Plasmodium falciparum malaria, but the precise nature of the protective effecthas proved diffic

205 involves dopaminergic disturbances, but the precise nature of those disturbances has remained elusiv

206 -serine participates in the establishment of precise neuronal connections during development.

207 tric diseases, emphasizing the importance of precise neuronal control of effector pathways.

208 vators that together are required to achieve precise neuronal specification during mouse development.

209 size, most confidence intervals will be over precise (not wide enough).

210 nables the dense VG3-AC plexus to contribute precise object motion signals to diverse targets without

211 ere we describe a method that allows for the precise optical control of oncogene expression in live z

212 This functional plasticity involves a precise orchestration of gene expression patterns whose

213 dividing cells, DNA replication occurs in a precise order, but many questions remain regarding the m

214 nge in the level of nuclear Smad3 was a more precise outcome of ligand stimulation.

215 een licking and bruxing, suggesting that the precise pattern of MLI activity depends on the nature of

216 s are a heterogeneous population, and a more precise phenotyping of these cells may help delineate di

217 We found that temporally precise photoinhibition of somatosensory cortex (S1) app

218 prosthetic devices which are capable of more precise point stimulation.

219 Precise polarization- and azimuth-dependent IRRAS data r

220 This is in contrast to other precise polyethylenes, where the chains are mostly trans

221 epresent the first example of a CPG in which precise premotor rhythms are tuned by motor neuron activ

222 cognizes HspQ via a C-terminal degron, whose precise presentation, in synergy with multipartite conta

223 However, the precise protein interactions between the different editi

224 D column, on which achiral separation allows precise quantification of each E and Z isomer of the ena

225 However, precise quantification of extremely low abundance protei

226 raphy-mass spectrometry method, which allows precise quantification of FA profile using small (<24 mm

227 se jejunum, serving as a fiducial marker for precise radiation targeting.

228 Precise reaction conditions were developed for the gener

229 Here, we extend such molecular-level precise reaction routes to nanochemistry, particularly t

230 es iteratively served as a ruler to template precise, regularly spaced upstream mRNA cleavage events.

231 segregation in mitosis is safeguarded by the precise regulation of kinetochore microtubule (k-MT) att

232 The precise regulation of Mr-OPY2 protein production is achi

233 Proper neural circuit formation requires the precise regulation of neuronal migration, axon guidance,

234 lation in growing axons allows for rapid and precise regulation of protein expression in response to

235 Precise regulation of the DNAzyme's oxidative catalysis

236 Its precise regulation represents a pivotal balance between

237 o arise from overlapping synaptic input, its precise relationship to local circuit architecture remai

238 aminants, ddPCR technology will produce more precise, reproducible and statistically significant resu

239 entiated, and that this effect allows a more precise response to external signals.

240 afficking is key in establishing a rapid and precise response.

241 pse properties, which thereby determines the precise responses of synapses to spike patterns in a neu

242 hippocampal neurons to elicit time- and dose-precise responses on neuronal voltage.

243 yping methodologies have proven sufficiently precise, robust, or scalable for association mapping to

244 these events is the basis for unraveling its precise role in health and disease.

245 However, the precise role of BM in this axis remains unknown.

246 ein, strongly predispose to AE; however, the precise role of FLG deficiency in AE pathogenesis remain

247 brane fusion in vivo is uncertain, as is the precise role of Munc18-2 during lytic granule exocytosis

248 However, the precise role of these cells in stimulating intestinal in

249 However, the precise role of ZNF750 in SCC cell biology remains uncle

250 evolution reaction (OER) catalysts, yet its precise role remains unclear.

251 The precise roles of the TL/TH in RNA synthesis and hydrolys

252 he analytical uncertainty analysis by a more precise, second-order Taylor series expansion.

253 of histone H3 in vitro and in vivo; however, precise selectivity of this domain has not been fully ch

254 dance, while attention per se is afforded to precise sensory evidence - or beliefs about the causes o

255 stinct functional clusters indicating a more precise separation of underlying neuronal clusters.

256 We also identified the precise sequence of the infectious particle-associated O

257 Reliable and precise signal transmission is essential in circuits of

258 inum microparticles are investigated through precise single particle collisions with two distinctive

259 rning structural integrity of the transgene, precise site of integration, or its impact on the host g

260 he main indication of acetaminophen, and the precise site of the relevant CB1 receptors have remained

261 ary C-H bond, the new catalyst is capable of precise site-selectivity at the most accessible tertiary

262 d to local translation, this process affords precise spatial and temporal control of protein function

263 s following deprivation may not maintain the precise spatial relationship between the two eye inputs

264 ncluding perinatal and neonatal stages, with precise spatiotemporal control but without surgical inte

265 in regeneration in planarians is mediated by precise spatiotemporal control of gene expression and is

266 Precise spatiotemporal gene regulation is paramount for

267 ain reaction-based approach to determine the precise species composition of mixed- Candida species bi

268 In this study, we determine the precise stage at which SLs influence nodulation.

269 haIIbbeta3 and alphaVbeta3 have resolved the precise structural location of each N-glycan site, but t

270 The generation of precise synaptic connections between developing neurons

271 Nervous system function relies on precise synaptic connections.

272 propose that this architecture may allow for precise synaptic information exchange and may be modulat

273 a-synucleinopathies, direct evidence for the precise synaptic localization has been difficult to achi

274 s neuronal differentiation, axon growth, and precise target innervation.

275 nity ligands and mutagenesis; however, their precise target interaction profiles fail to provide comp

276 and other caspase active sites have hampered precise targeting of caspase-6.

277 ce percepts and that this effect depended on precise targeting to the center of face patches.

278 we used naturalistic outdoors mesocosms with precise temperature control.

279 oteins were quantified, revealing, e.g., the precise temporal regulation of the SigB-dependent stress

280 MU-specific synaptic changes occurring in a precise temporal sequence.

281 developed explosively largely because of the precise theoretical predictions, well-controlled materia

282 beta has allowed for the development of more precise therapeutic interventions targeting the most rel

283 patients at-risk, or guiding mechanistically-precise therapies.

284 because these reactions can be performed in precise three-dimensional space and at specific moments

285 bust, automated image analysis to detect the precise time at which fibers distort ("sickle") the cell

286 tein to ensure that an event will occur at a precise time, while minimizing deviations or noise about

287 Precise timekeeping is critical to metrology, forming th

288 re actually highly dynamic, changing size at precise times during germ cell development.

289 The precise timing and sequence of changes in expression of

290 of synapses are tightly orchestrated by the precise timing of expression of specific molecules durin

291 Here, we demonstrate how the precise topography of the long (L)-, middle (M)-, and sh

292 Life on land would have selected for the precise traits that now allow pathogenic enterococci to

293 The precise underlying circuitry of this cholinergic input t

294 den associated with pain management, yet its precise underlying mechanism and prevention remain elusi

295 All RAS biology occurs in membranes: a precise understanding of RAS' interaction with membranes

296 hese findings have enabled a deeper and more precise understanding of the transcriptional mechanisms

297 A precise understanding of these layers of control has imp

298 implies that phenotypic markers give a more precise view of mutation rate than previously believed:

299 Here, by using techniques that allowed a precise visualization of the heteromers in situ in combi

300 Targeting Treg cells or CTLA-4 in this precise window accelerated parasite clearance and genera