ライフサイエンスコーパス: precisely

1 he formation of benzoquinoline was described precisely.

2 nd determines their orientation and location precisely.

3 o control the dynamics of the optical signal precisely.

4 pture rheological changes extremely fast and precisely.

5 was investigated, mapping its selection rule precisely.

6 indispensable to compute the quality factors precisely.

7 ble to control the redox state of the enzyme precisely.

8 may influence the ability to regulate forces precisely.

9 are possible, and the consequent ability to precisely abrogate specific MMP activity could contribut

10 e photo-cured individually, on-the-fly, with precisely-actuated, millisecond-length (70 ms), uniform-

11 motion (i.e., a ground velocity that is not precisely aligned with body orientation) typical of bee

12 RNA editing is a cellular process that precisely alters nucleotide sequences, thus regulating g

13 ements wherein a user-programmable set-point precisely alters the protein concentration in the cell w

14 terize the course of these infections and to precisely analyze biofilm development.

15 rmit focal or broad illumination that can be precisely and dynamically matched to experimental needs.

16 nsor, which is composed of five chambers, is precisely and individually controlled using in-house-bui

17 ibody-antigen-antibody (Ab-Ag-Ab) complex by precisely and rapidly assembling carbon nanotubes (CNT)

18 r response to therapy can be assessed early, precisely, and in high agreement with histologic finding

19 s to offset this, it is important to know as precisely as possible the capabilities of these potentia

20 ical devices which do not necessarily behave precisely as the theory expects.

21 Therefore, analytical tools that can precisely assess a wide range of exchange rates within s

22 ASY3, are extensively phosphorylated, and we precisely assign phosphorylation sites.

23 2 assays that in the future may help to more precisely assign therapies counteracting cancer cell pro

24 s new "nanomapping" method to detect and map precisely BCL2-IGH translocations present in lymph node

25 diverging significantly from the main groups precisely because they showed a good ability to produce

26 inference and therefore could not be assayed precisely by TREDPARSE.

27 of empirical findings are first used to more precisely characterize our distinctive tendency to objec

28 We precisely characterized two associations involved in fru

29 phase retardation through the metasurface is precisely characterized with an optical vortex based int

30 FEN1 precisely cleaves single-stranded (ss) 5'-flaps one nucl

31 provided candidate functional variants that precisely co-locate with cell-specific chromatin domains

32 YLDV-97 were constructed, but only one that precisely combined the N domain of VACV-A6 and the C dom

33 By designing precisely configured plasmonic molecules of varying comp

34 e the density of active Rac1 at membranes to precisely control actin assembly.

35 MBF using prospective end-tidal targeting to precisely control arterial Pco2 and PET to measure the o

36 re we devise a universal genetic strategy to precisely control copy number of fluorescently labeled m

37 nderneath aromatic rings can be exploited to precisely control electrophilic aromatic substitutions.

38 ssociated with advanced functions.Nature can precisely control monomer sequences in biopolymers, but

39 The delicate SME reaction opens a door to precisely control the alloying sites in the protecting s

40 stem cell-specific oxygen signaling pathways precisely control the balance between muscle growth and

41 eady-state chemostat cultures where we could precisely control the cell growth-rate.

42 sociated with their complexity, inability to precisely control the dimensions, and limited possibilit

43 oengineered 'microfluidic chest cavities' to precisely control the mechanical environment of the feta

44 By bioprinting neuronal constructs, one can precisely control the microenvironment by specifically f

45 to discover new self-assembly modalities to precisely control the placement of small particles in sp

46 The ability to precisely control the transport of single DNA molecules

47 ation of objects with complex geometries and precisely controllable shape morphing potential, while d

48 The gating of AMPARs occurs in milliseconds, precisely controlled by a variety of auxiliary subunits

49 Further, nano-peptisome size can be precisely controlled by simply modulating the starting p

50 ate that ArnS plays an essential role in the precisely controlled expression of archaellum components

51 owing to track migratory responses of DCs to precisely controlled immobilized gradients of CCL21.

52 fates generated by each neuroblast are very precisely controlled in a cell autonomous manner, after

53 ted and exemplifies how a phospho-network is precisely controlled in different cellular contexts.

54 how that the anion-exchange chemistry can be precisely controlled in single-crystalline halide perovs

55 This work shows that precisely controlled integrin activation from a biomater

56 ution nanofabrication utilizing ultranarrow, precisely controlled ion or laser beams have enabled ass

57 ling features including downscaled analysis, precisely controlled local environment, and enhanced spe

58 oble metals, and their bimetallic alloy with precisely controlled sizes ( approximately 1 nm) and rec

59 UCNPs with precisely controlled sizes between 10 and 43 nm were pre

60 This first use of a precisely controlled solvent free inkjet printing to pro

61 Se2-WS2-WSe2-WS2) were readily prepared with precisely controlled spatial modulation.

62 revealing a striking freedom in an otherwise precisely controlled system.

63 This massive iron flux must be precisely controlled to permit the coordinated synthesis

64 Thickness of the deposited polymer film is precisely controlled with the number of current oscillat

65 cal and pharmacokinetic properties have been precisely controlled.

66 ause their physicochemical properties can be precisely controlled.

67 ic background and rearing environment can be precisely controlled.

68 o assess peptide activity and selectivity by precisely controlling exposure to vesicles with lipid co

69 opened the door to the longstanding goal of precisely controlling molecular internal and external de

70 Using new methods for precisely controlling retinal stimulation, here we show

71 ed from ReSe2 (1.32 eV) to ReS2 (1.62 eV) by precisely controlling the growth conditions.

72 ng is largely due to technical challenges in precisely controlling the membrane curvature in live cel

73 functionally organized into a hierarchy that precisely controls stepping in a stereotypic, speed-depe

74 at they are already selective as a result of precisely converging inputs from similarly tuned retinal

75 ase editing efficiently inactivates genes by precisely converting four codons (CAA, CAG, CGA, and TGG

76 th pathways interact in postmitotic cells to precisely coordinate cell-specific output.

77 d, proliferation and differentiation must be precisely coordinated for proper cardiac morphogenesis.

78 ation of axons in peripheral nerves requires precisely coordinated proliferation and differentiation

79 ation, and the importance of HAdV 5'UTRs for precisely coordinated viral protein expression along the

80 utamate, acetylcholine, and GABA signals are precisely coordinated.

81 poly-(amidoamine) (PAMAM) dendrimers with a precisely core positioned single sulforhodamine B molecu

82 in most of those patients, clinical symptoms precisely correlated with grass pollen counts.

83 The fidelity of recognition is not precisely correlated with the fraction or total number o

84 is still a challenge to construct MOFs with precisely customized pore apertures for specific applica

85 Here, we use precisely dated and seasonally-resolved stalagmite oxyge

86 ical and microbial DNA evidence preserved in precisely dated subglacial calcites from close to the Ea

87 hip becomes most apparent when comparing two precisely dated, high-resolution paleorainfall records f

88 Using this code, we could precisely decode faces from neural population responses

89 We precisely define morphological types of TO sensilla taki

90 To more precisely define the positions from which certain intron

91 tenated gene constructs were used to express precisely defined alpha3beta4*-nAChR isoforms (alpha3bet

92 is have yielded new nanoscale materials with precisely defined biochemical features, and emerging ana

93 f uniform hexamers and graft copolymers with precisely defined branches.

94 During this process, cellular identity is precisely defined by signaling cues that tailor the chro

95 Herein, we demonstrate that a precisely defined consortium of commensal bacteria conta

96 Uniform synthetic polymers with precisely defined molar mass and monomer sequence (prima

97 Large-scale fabrication of precisely defined nanostructures with tunable functions

98 esonance imaging to measure BOLD activity at precisely defined receptive field locations in visual co

99 c and hydrophilic molecular nanoparticles in precisely defined sequence and composition to investigat

100 ary to the sites of Mcm2-7 recruitment being precisely defined, only single roadblocks that inhibited

101 The template is precisely defined, processively copied, and regenerated

102 tumour NGS data succeeded in separating and precisely defining at least 30 distinct patterns of sequ

103 Precisely defining how viral mutations affect HIV's sens

104 We used homologous recombination to precisely delete foraging, generating the for(0) null al

105 topharmacology describes the use of light to precisely deliver drug activity in space and time.

106 The ability to reliably and precisely deliver picolitre volumes is an important comp

107 unanswered due to a lack of technology that precisely delivers plant hormones, based on cyclic alkan

108 om magnetic domain wall motion, which can be precisely depicted using the standard cooperative coordi

109 surface scattering theory with shadowing to precisely describe phonon-surface interactions.

110 network structure and average polyandry more precisely describes the strength of sexual selection.

111 tical production in CHO cells that exhibited precisely designed activity dynamics and long-term expre

112 therefore the difficulty to specifically and precisely detect analytes in the biological sample.

113 The ability to precisely detect and quantify CTCs and ctDNA could minim

114 lls as a general sensor-response platform to precisely detect disease, to remodel disease microenviro

115 change as response to the gating voltage is precisely detected by in situ electron spin resonance me

116 on hard X-ray microprobe (SHXM) data sets to precisely determine the distribution, valence state, and

117 s is also the reason that it is difficult to precisely determine the transition point employing the u

118 aging, we assessed structural impurities and precisely determined molar concentrations of the (8,6) a

119 studies will exploit these genetic tools to precisely dissect the isoform- and tissue-specific requi

120 complex, a set of genes whose expression is precisely downmodulated upon culture of splenic transiti

121 The ability to precisely edit and modify a genome opens endless opportu

122 ls, tailored S1mplexes increase the ratio of precisely edited to imprecisely edited alleles up to 18-

123 s generated from each edited population were precisely edited.

124 to fivefold reduction in the time needed to precisely encode grating direction and orientation.

125 hanical behaviour of biological materials by precisely encoding their stress-strain curves in solvent

126 , image and control protein function, and to precisely engineer therapeutics.

127 lopment of cinnabar HgS NCs that can possess precisely engineered chirality originating from both ato

128 of nanoparticles of suitable materials with precisely engineered composition and surface chemistry,

129 ation 'smart' nanoparticle systems should be precisely engineered in size, shape and composition to i

130 Precisely engineering the electrical conductivity repres

131 al cells, but how its branching patterns are precisely established is not clear.

132 We aimed to more precisely estimate the effects of more intensive glucose

133 findings in larger samples is needed to more precisely estimate variance explained and to establish t

134 fumarase, and urease, can be accurately and precisely estimated from a minimal amount of timecourse

135 iary analysis (all studies; n=2332 patients) precisely estimated the changes in ankle brachial index,

136 suggested by several studies, remains to be precisely evaluated, particularly in a long-term perspec

137 ture, namely, pendant carboxylic acid groups precisely every 21st backbone carbon atom.

138 a strong 5'-dsDNA exonuclease activity that precisely excises a dinucleotide using an intrinsic 'tap

139 the development of quantitative platforms to precisely follow and measure subcellular and molecular e

140 apping, we demonstrate that this boundary is precisely formed with minimal overlap between En1 and Db

141 ne-interaction mechanisms of ABPs evolved to precisely fulfill their specific functions in cytoskelet

142 little as 100 bps of total coding space can precisely generate small interfering RNAs (siRNAs) that

143 These consequences are the precisely goals of therapeutic interventions in human an

144 However, precisely how and why the FA traction oscillates is unkn

145 Precisely how cellular DNA gains access to the cytoplasm

146 rincipal site for detecting such agents, but precisely how it communicates with neural elements is po

147 acellular cysts demarcated with a cyst wall, precisely how it sustains itself and remodels organelles

148 KEY POINTS: It is unclear precisely how macromolecules (e.g. endogenous proteins a

149 However, precisely how Mediator impacts the PIC, especially post-

150 ged by a particular bursting bubble, or more precisely how much volume around the bubble experiences

151 ecisive role, and a general understanding of precisely how network topology creates instability remai

152 However, precisely how tau becomes toxic is unclear.

153 ng values of T2 requires an understanding of precisely how the position of nuclear spins relative to

154 o date, there is incomplete understanding of precisely how the three DNMTs, 1, 3A, and 3B, interact f

155 Maximizing this potential requires defining precisely how these enzymes maintain genome-wide, cancer

156 Thus, precisely how these mutations inactivate BAP1 is unknown

157 Precisely how this primary epithelium maintains continuo

158 Nor is it known precisely how villus cell migration is affected when pro

159 Moreover, PD-1 precisely identified marrow-infiltrating, myeloma-specif

160 Our method precisely identifies DNA positioning on nucleosome by co

161 ) and related structure-specific 5'nucleases precisely identify and incise aberrant DNA structures du

162 he results show that our method not only can precisely identify chromatin accessibility but also outp

163 Identifying cell lines and cell types precisely in publications is crucial for science reprodu

164 nism to activate gene expression rapidly and precisely in response to temperature, while preventing l

165 how sharp boundaries of gene expression form precisely in spite of biological variation/noise.

166 a fast encoding mechanism that can serve to precisely initiate startle responses when speed is criti

167 solvated electron and liquid structure to be precisely interrogated.

168 -null hESCs exposed to Activin differentiate precisely into beating cardiomyocytes without further tr

169 We have performed experiments to more precisely investigate this point and to discriminate bet

170 we used serum samples (n = 792) from pigs of precisely known infection status and a multiplex fluores

171 ntrast to spider silk, these proteins have a precisely known sequence-structure relationship.

172 n efficiency are key parameters that must be precisely known when designing in vitro and in vivo test

173 It is not precisely known, whether habenular input to the aVTA, pV

174 llular and molecular pathomechanisms are not precisely known.

175 throughout adolescence and, by establishing precisely localized synapses, calibrates cognitive funct

176 d speed just controlled by light, as well as precisely manipulate particles for nanoengineering.

177 We also provide a conceptual framework to precisely manipulate the dryland microbiome to mitigate

178 Nature precisely manipulates primary monomer sequences in biopo

179 B1 fine-tunes host phytohormone crosstalk by precisely manipulating part of the JA regulon to avoid p

180 To precisely map genomic regions, high-density linkage maps

181 We precisely map RNA-programmed DNA methylation to targeted

182 nes in archival colorectal cancer samples to precisely map the spatial and morphological context of m

183 pact on transcription can be investigated at precisely mapped genomic DSBs is essential to study this

184 says, and quantitative mass spectrometry, we precisely mapped key residues involved in substrate reco

185 work, but also how their dysfunction can be precisely mapped onto behavioral and cognitive deficits.

186 less the patch pipette and GUV pressures are precisely matched in the GUV-attached configuration, bre

187 rotein assemblies with binding functionality precisely matched to homo-oligomeric target sites.

188 We use these data sets to precisely measure mutational rates and patterns.

189 The precisely measured acoustic wave travel times which were

190 a PLD using a Fe0.94Se0.45Te0.55 target, the precisely measured composition indicates a Se-rich FeSex

191 e these parameters with a new technique that precisely measures small selective differences between s

192 Thus, DD-SRM holds great promise for precisely measuring extremely low abundance proteins or

193 ing RNA with pairs of heavy atom probes, and precisely measuring the distribution of inter-probe dist

194 Precisely measuring the location and frequency of DNA do

195 e and anchor one end of this linear array to precisely meter C4 into close proximity to the catalytic

196 e includes sgSTOPs that could be employed to precisely model over 32,000 cancer-associated nonsense m

197 s between these two regulatory proteins that precisely modulate the level of active Galpha, consequen

198 Apcdd1 thus serves to precisely modulate Wnt/Norrin signaling activity in the

199 rties of conducting polymer microcups can be precisely modulated to control electrical properties and

200 ies is to identify reaction coordinates that precisely monitor conformational rearrangements.

201 al design of ionophores that can rapidly and precisely monitor molecular ions relevant to environment

202 dition, this strategy affords the ability to precisely monitor the efficiency of drug conjugation wit

203 tage can be chosen for any nanosuspension to precisely operate in the microdripping mode at a predete

204 This precisely orchestrated mechanism of CRL3(GCL) function a

205 In mitosis, cells undergo a precisely orchestrated series of spatiotemporal changes

206 However, to appropriately deliver oxygen, a precisely organized and exquisitely responsive microcirc

207 000 different types of odorant receptors are precisely organized and sorted out onto 1800 glomeruli i

208 in layers provide a "bottom-up" approach for precisely organizing functional elements at the nanoscal

209 A chemical strategy is described to precisely perturb a specific molecular interaction betwe

210 reproducible fashion, and the capability to precisely place nanoantennas into devices with nanometer

211 More precisely, plasmonic extinction spectra and near-field e

212 lp2-dependent midzone targeting cooperate to precisely position the CPC during mitotic exit, and that

213 t in either direction, making it possible to precisely position the line at a desired location.

214 ific antibodies in which the LAIR1 domain is precisely positioned at the elbow between the VH and CH1

215 We report a method of precisely positioning a Hg-based ultramicroelectrode (UM

216 rotein entirely from first principles with a precisely predetermined structure has not been demonstra

217 the capability of quantum electrodynamics to precisely predict transition frequencies, and modern mea

218 mall ncRNAs, such as miRNAs in exosomes, and precisely processed tRNA and Y RNA fragments in EVs and

219 ion rates of 5microMh(-1) were monitored and precisely quantified over three days.

220 To delineate the mechanism in zebrafish, we precisely quantified the BMP activity gradient in wild-t

221 ned mice to discriminate two visual stimuli, precisely quantified when learning happened, and measure

222 transfer area, and liquid pressure on CHF is precisely quantified.

223 ed ability to sensitively, specifically, and precisely quantify and characterize the whole-body burde

224 This investigation aims to precisely quantify the process deficit in anxious indivi

225 sing multiple reaction monitoring method, we precisely quantify these previously undetected low-abund

226 Little is known about the ability to precisely regulate forces or torques during unexpected d

227 nic polymerization has emerged as a means to precisely regulate polymer chain growth.

228 Hair follicles (HFs) undergo precisely regulated cycles of active regeneration (anage

229 thelium that contains progenitors undergoing precisely regulated divisions at its most apical side, t

230 Gene expression is precisely regulated during the inflammatory response to

231 DNA replication, chromosome condensation and precisely regulated partitioning of chromosomes into dau

232 lfactory transduction machinery to work at a precisely regulated range of response kinetics for robus

233 e mechanism of metered secretory output that precisely regulates release of the incretin hormone GLP-

234 vely parallel single-cell RNA sequencing can precisely resolve cellular diversity in a high-throughpu

235 Single-cell RNA-seq can precisely resolve cellular states, but applying this met

236 To precisely respond to a changing external milieu, human c

237 various domain phases that can be easily and precisely selected by external tuning parameters such as

238 The ability of oxidative phosphorylation to precisely set and maintain metabolic homeostasis is cons

239 Precisely size- and geometry-tuned nanopores could find

240 Participants produced an inner phoneme at a precisely specified time, at which an audible phoneme wa

241 ponding to guidance cues, during which cells precisely steer their growth toward the source of guidan

242 The device can be precisely steered toward a targeted location wirelessly

243 The method involves precisely step-heating a mineral sample, allowing the se

244 e of different physiological phenomena, from precisely synchronized spiking to broadly simultaneous r

245 Precisely tailored plasmonic substrates can provide a pl

246 es, functionalities, and dynamics can all be precisely tailored through a simple three-component asse

247 e antivascular method with the capability to precisely target blood vessels.

248 We found that these manipulations, precisely targeted at the decision point, were sufficien

249 region of these rotors was specifically and precisely targeted by light to induce local conduction b

250 r insight into such redox biology may enable precisely targeted manipulation of ROS for effective med

251 a connective approach to olefins capable of precisely targeting a given isomer regardless of the nat

252 the reduction of outcome disparities by more precisely targeting patients' treatment.

253 This approach shows potential for precisely targeting, in time and space, endogenous recep

254 a new analytical instrument that combines a precisely temperature-controlled hot-stage with digital

255 are stored significantly more accurately and precisely than intermediate rewards.

256 y affect the risk for heart dysfunction more precisely than the change in TBW.

257 strates with different pore radii to address precisely the extent of the geometric constraint, permit

258 or responding to, the same aversive outcome, precisely the goals of therapeutic interventions in huma

259 Thus, precisely the large accumulations above the cutoff that

260 To map precisely the life-span trajectory of this key visual co

261 egative supercoiling [(-)sc] in the region - precisely the opposite of that assumed.

262 (b) data are relatively sparse and, indeed, precisely the same situation may never be encountered tw

263 h-initial-migration (IIM) model, which drops precisely this assumption.

264 It is precisely this localization that allows one to intuit ho

265 carrying the complete ortholog of PRDM9 are precisely those with rapid evolution of its predicted bi

266 tic substitution reaction, which is directed precisely through space.

267 e generation of postsynaptic spikes that are precisely time locked to presynaptic spikes.

268 ts of the composite materials, followed by a precisely time-delayed electron pulse to visualize the i

269 This process relies on precisely timed interactions between Wnt/beta-catenin an

270 y convert brief membrane depolarization into precisely timed intracellular signaling events in the ma

271 er towards or away from light by a rapid and precisely timed modulation of their flagellar activity.

272 complex motor programs that require multiple precisely timed muscle contractions, such as, for exampl

273 k the temporal precision necessary to induce precisely timed spiking events.

274 its regulate the activity of principal cells precisely to drive olfactory-guided behavior.

275 ocal environment, which allows them to adapt precisely to the needs of their anatomical niche.

276 leads to a smoother contact pattern and more precisely tractable chromosome conformations, and the la

277 fMRI analytic approach was used to quantify precisely trialwise associations between reaction time a

278 hacrylate for the synthesis of polymers with precisely tunable molecular weights and dispersities typ

279 growth, we were able to, for the first time, precisely tune both the size and width of the AuNP frame

280 grade Ca(2+) spark/STOC production and thus precisely tune negative electrical feedback.

281 A methodology is described to precisely tune stress relaxation in PEG networks formed

282 heterovalent Bi(3+) ions by hot injection to precisely tune their band structure and excited-state dy

283 Rho GTPase activity needs to be precisely tuned at distinct cellular locations to enable

284 hose structure and elastic properties can be precisely tuned by controlling the geometry of the eleme

285 effective bandgaps of nano-ring LEDs can be precisely tuned by reducing the strain inside the active

286 inical or at-risk populations, we must first precisely understand typical brain development and how c

287 Thus, the cell must precisely up- and down-regulate IFNalpha to achieve immu

288 By precisely varying FGF, BMP, WNT, and TGFbeta pathway act

289 More precisely, we identified two well-differentiated, nonpro

290 More precisely, we identify a certain class of projective uni

291 More precisely, we show theoretically that a Bayesian estimat

292 Precisely, we will focus on conjugation machinery in the

293 lvement, and high memorability, and hence is precisely what artworks strive for.

294 Consequently, identifying precisely what face information elicits different social

295 nce over long periods of time, it is unclear precisely what mechanisms benefit from rest after short

296 Specifically, such genes are expressed precisely when the neighboring CGI is unmethylated but r

297 ed to report, after indicating their choice, precisely when they felt they had made a decision, suppo

298 e term compartmental domains that correspond precisely with A/B compartments at high resolution.

299 Moreover, the Dhb signal correlates precisely with the activation of the Shigella type III s

300 ing vaguely right may be preferable to being precisely wrong.