ライフサイエンスコーパス: preemptive

1 In all, 44% were preemptive.

2 Of 3606 transplants, 28% were preemptive, 38% followed pretransplant hemodialysis (HD)

3 tanding the causes of instability and taking preemptive actions will facilitate the development of rM

4 r data support a hypothesis that a concerted preemptive activation of the pentose phosphate pathway,

5 is study was unable to provide evidence that preemptive administration of an echinocandin was effecti

6 ection at the surgical site, though not as a preemptive analgesic, has recently been demonstrated to

7 We compared outcomes of 3509 preemptive and 14,075 nonpreemptive second kidney transp

8 man (or humanized) mAbs for the prophylaxis, preemptive and acute treatment of viral infections has b

9 ecological invasion when combined effects of preemptive and interference competition govern interacti

10 Preemptive and multiple-organ transplants were excluded.

11 nt strategy assessment such as prophylactic, preemptive, and empirical therapy.

12 medicine refers to predictive, personalized, preemptive, and participatory medicine and was the inspi

13 Trials assessing preemptive anti-CMV therapy may be warranted.

14 formation by peptidylarginine inhibition or preemptive anti-histone IgG injection significantly redu

15 ukocyte antigen (HLA) antibodies (DSA) and a preemptive antibody-directed therapy protocol consisting

16 e-blind, placebo-controlled trial assessed a preemptive antifungal approach with micafungin (100 mg/d

17 invasive candidiasis, tests will facilitate preemptive antifungal strategies.

18 uide clinicians in the use of prophylaxis or preemptive antifungal therapy in high-risk patients.

19 invasive candidiasis (IC) and candidates for preemptive antifungal therapy.

20 Use of preemptive antifungal treatment for 3 months may be asso

21 Preemptive antifungal treatment for 3 months was signifi

22 macrophage control of TMEV infection through preemptive antiviral nitric oxide production and antivir

23 Despite pretransplant lymphoid depletion, preemptive antiviral therapy and minimization of posttra

24 CMV was managed using preemptive antiviral therapy and no patient received ant

25 prevention of virus-induced complications by preemptive antiviral therapy in renal allografts.

26 y 10% of lung transplant recipients, despite preemptive antiviral therapy, and is more common among D

27 included reduction in immunosuppression and preemptive antiviral therapy, at the discretion of the a

28 patient with detectable viremia who received preemptive antiviral therapy, suggesting that the adapti

29 load was introduced in 1994 with adoption of preemptive antiviral therapy.

30 r the past decade, most centers have adopted preemptive antiviral treatment or prophylaxis strategies

31 Preemptive application of APRV blocked early drivers of

32 2) and 18.8% (22/117), respectively, for the preemptive approach (P = .04); however, this analysis in

33 was significant among patients followed by a preemptive approach (SHR, 1.46 [95% CI, 1.01-2.12]; P =

34 The preemptive approach analysis included patients all patie

35 eal-time PCR has become the most widely used preemptive approach for managing cytomegalovirus (CMV),

36 ients and emphasize the effectiveness of the preemptive approach for prevention of CMV syndrome and e

37 A preemptive approach for the management of patients at hi

38 d to develop forecasting tools toward a more preemptive approach to outbreak investigation.

39 Implementing a different and preemptive approach with a low risk profile may be very

40 atio, 242.96 [24.82]) and was prevented with preemptive APRV (mean [SE] PaO2/FIO2 ratio, 478.00 [41.3

41 n other transplant contexts, the efficacy of preemptive B cell depletion to modulate alloimmunity or

42 cell-deficient mice but can be recovered by preemptive B lymphocyte transfer to B cell-deficient hos

43 A focus on preemptive cardiac regeneration in the pediatric setting

44 Yet, in practice both protective and preemptive changes in behavior come with costs.

45 s by simulating an individual-based model of preemptive competition.

46 date to simultaneous IAT during nonemergency preemptive completion pancreatectomy through the pancrea

47 These results imply that controversial preemptive control measures may be unnecessary; instead,

48 re lacking regarding the long-term effect of preemptive conversion to everolimus from calcineurin inh

49 Herein, we propose a concept, preemptive coordination (PC), for targeting positively c

50 s helpful for defining prognosis and whether preemptive coronary intervention reduces the incidence o

51 Similarly, in a xenograft model the preemptive cotreatment of lung tumor cells with an EGFR

52 ining short-course antiviral prophylaxis and preemptive cytomegalovirus (CMV) polymerase chain reacti

53 in the first 180 days after transplant with preemptive DDK (3.7% vs. 1.1%; P=0.03) and similar morta

54 ving a pancreas transplant (LDK/noP, n=289), preemptive DDK (n=112), and preemptive SPK transplantati

55 a trend toward increased risk of death with preemptive DDK compared with preemptive PALK (hazard rat

56 : LDK/noP=0.08; SPK=0.85) but was lower with preemptive DDK versus preemptive PALK (P=0.03).

57 vation becomes so high (>300 degrees C) that preemptive decomposition prevents its measurement.

58 spiratory depression dismissed, and vigorous preemptive deep sedation or anesthesia provided.

59 sue of the JCI, Kelishadi et al. report that preemptive deletion of B cells prior to heart transplant

60 We conclude therefore that efficient preemptive depletion of CD20+ B cells is effective in a

61 kR1/pikR2-based bacterial resistance and the preemptive development of drugs that can remain effectiv

62 ear isodars, which suggests a 'despotic' or 'preemptive' distribution of individuals across habitats,

63 This form of preemptive donor apoptotic cell infusions has significan

64 ed Th2/Th1 phenotype, were administered as a preemptive donor lymphocyte infusion at day 14 post-HCT.

65 Prophylactic or preemptive donor lymphocyte infusion may be useful, but

66 s on metabolic stress responses; and (6) the preemptive effect.

67 Furthermore, they suggest that preemptive elimination of CD59-overexpressing subpopulat

68 Preemptive erythropoietin might blunt the benefit of RBV

69 Pre-ART CRAG screening with preemptive fluconazole treatment and improved CM treatme

70 screening of individuals initiating ART and preemptive fluconazole treatment of CrAg-positive patien

71 ylactic group (8%) compared with none in the preemptive group (0%) died with a functioning graft, P=0

72 year acute rejection rate was lowest for the preemptive group (36%) compared with the HD (45.5%; P=0.

73 tients in each group, and one patient in the preemptive group developed CMV disease.

74 Thirty-seven percent of patients in the preemptive group developed CMV DNAemia, 68% of these pat

75 oring costs were significantly higher in the preemptive group, whereas medication cost was significan

76 ed similarities between the prophylactic and preemptive groups.

77 Preemptive hematopoietic stem cell transplantation does

78 ress in FA patients, for whom the concept of preemptive HSCT is discussed.

79 This study compares efficacy of preemptive ibuprofen and dexamethasone protocols for pai

80 quently than their nondiabetic counterparts, preemptive identification and anticipation of diabetic c

81 Preemptive (ie, after remission) administration of ritux

82 influenza virus carrying the same mutation, preemptive immunization against these escape variants le

83 ssion in 51 patients, mixed chimerism in 18, preemptive in 10, and other in 2.

84 We have previously shown that preemptive infusion of apoptotic donor splenocytes treat

85 g an unprecedented shift toward large-scale, preemptive insecticide use: 34-44% of soybeans and 79-10

86 sk of restenosis allows for consideration of preemptive intervention strategies for these high-risk v

87 ents at high risk for progression may permit preemptive intervention strategies to avoid adverse coro

88 ion that is comparable to that achieved with preemptive intravenous therapy with GCV.

89 ecipients (P<0.001) and was less frequent in preemptive kidney graft recipients (P=0.002).

90 Five years after HSCT, he received a preemptive kidney transplant from his father.

91 ansplantation hypophosphatemia were lower in preemptive kidney transplant recipients than in patients

92 essed slowly to CKD, which was followed by a preemptive kidney transplant.

93 Preemptive kidney transplantation (preKT) is associated

94 Preemptive kidney transplantation (prior to the institut

95 re was a slight increase in the frequency of preemptive kidney transplantation at ESRD onset, but kid

96 With prompt referral and workup, preemptive kidney transplantation can be performed succe

97 Preemptive kidney transplantation is the optimal treatme

98 tional Kidney Foundation CKD stage 4 or 5 or preemptive kidney transplantation, were identified using

99 ney failure, defined as need for dialysis or preemptive kidney transplantation.

100 Twenty-four patients underwent preemptive KTX and 69 received a living-donor KTX.

101 time of kidney transplant) of pancreas after preemptive LDK (PALK, n=389), preemptive LDK not receivi

102 pancreas after preemptive LDK (PALK, n=389), preemptive LDK not receiving a pancreas transplant (LDK/

103 subsequently transplanted), and 1 received a preemptive live donor KT without listing or ever receivi

104 9m)Tc-DMSA) renal scintigraphy in 2 cases of preemptive LKT demonstrated preserved native kidney resi

105 A preemptive management approach to patients at high risk

106 interventions may improve the prevention or preemptive management of this life-threatening infection

107 Finally, preemptive management strategies are outlined in certain

108 iviral therapy, and that evidence concerning preemptive management with CMVIG is limited, but promisi

109 als cannot eradicate the disease without the preemptive measures of the sick individuals.

110 Sick individuals may utilize preemptive measures to avoid spreading a disease.

111 Preemptive measures to prevent potential invasive specie

112 ft rejection and provides an opportunity for preemptive monitoring and treatment.

113 ll cost of (1) universal prophylaxis and (2) preemptive monitoring are similar, universal prophylaxis

114 laces the cost burden on the patient whereas preemptive monitoring shifts the cost burden to the heal

115 menting, as standard of care, an abbreviated preemptive monitoring strategy compared with universal p

116 ry 2007 and December 2007 were enrolled in a preemptive monitoring strategy that included no anti-CMV

117 During a 2015 preemptive OCV campaign among internally displaced perso

118 gher policy stance favoring the retention of preemptive oil and gas statutes.

119 The resulting reduced costs allow preemptive or compensated coercion to be an instantaneou

120 r secondary prophylaxis and diagnostic-based preemptive or empiric therapy.

121 -controlled study evaluating the efficacy of preemptive oral ganciclovir for the prevention of CMV di

122 Preemptive oral ganciclovir therapy diminished the incid

123 tients had persistent CMV replication during preemptive oral ganciclovir therapy; 2 patients subseque

124 Both prophylactic and preemptive oral valganciclovir therapy are effective for

125 rent study was to compare recent outcomes of preemptive (P) versus nonpreemptive (NP) living donor ki

126 lar between groups (83% prophylactic vs. 81% preemptive, P=0.754).

127 k of death with preemptive DDK compared with preemptive PALK (hazard ratio: 1.91; 95% confidence inte

128 85) but was lower with preemptive DDK versus preemptive PALK (P=0.03).

129 0.0001), with the highest incidence in D+/R+ preemptive patients (53.8% vs. 15.6%, P<0.0001).

130 450 mg oral valganciclovir/day for 100 days; preemptive patients were monitored by CMV-polymerase cha

131 on was strategy compliance: 41% (7 of 17) of preemptive patients who developed CMV missed at least 1

132 Preemptive pharmacologic inhibition of Tgf-beta signals

133 sponse to influenza virus infection and that preemptive priming of CD4 T cell help can promote effect

134 D risk in F-->M HCT patients and may support preemptive prophylaxis therapy for cGVHD beginning at 3

135 gh the translocon complex are subjected to a preemptive quality control (pQC) pathway and are degrade

136 The preemptive quality control (pQC) pathway protects cells

137 P(Sc), via ER stress and the activation of a preemptive quality control process, to neurodegeneration

138 Seventy-eight patients receiving preemptive R between January 2005 and January 2010 were

139 e infections and immune reconstitution after preemptive R treatment of EBV infection.

140 Preemptive re-treatment decisions can be individualized

141 Preemptive recipients had less acute rejection (12% vs.

142 of death-censored graft loss was observed in preemptive recipients when first transplant survival was

143 Moreover, preemptive reduction in immunosuppression is most effect

144 of up to 1% of each adulterant, allowing the preemptive rejection of suspect samples.

145 itourinary tract may allow for a planned and preemptive renal transplant, thus avoiding dialysis.

146 l of this study was to determine barriers to preemptive renal transplantation.

147 Adults receiving preemptive renal transplants have better allograft survi

148 or hemophilia, which is currently managed by preemptive replacement therapy.

149 re, we demonstrate that sleep loss amplifies preemptive responding in the amygdala and anterior insul

150 the platelet-dependent axis has evolved as a preemptive response to local stress, priming the body ag

151 nt consisting of return to dialysis therapy, preemptive retransplantation, or death with function).

152 he first allograft, with 10 of 31 undergoing preemptive retransplantation.

153 Alternative short-term approaches aimed at preemptive risk stratification and prevention are needed

154 S13 deficiency during remission, 30 received preemptive rituximab (group 1); the other 18 did not (gr

155 Preemptive rituximab (R) treatment decreases the inciden

156 ompare the relapse incidence with or without preemptive rituximab infusion.

157 TTP remission should prompt consideration of preemptive rituximab to prevent relapses.

158 Our data support a preemptive role for the RdgB homologs in excluding endog

159 ed donor kidney (DDK) transplantation in the preemptive setting are unknown.

160 Our data encourage evaluation of preemptive solitary liver transplantation early in the c

161 vs. 1.1%; P=0.03) and similar mortality with preemptive SPK (2.3%; P=0.07).

162 LDK/noP, n=289), preemptive DDK (n=112), and preemptive SPK transplantations (n=1402) were compared.

163 ne elevated LDL levels or low HDL levels and preemptive statin usage were associated with higher SVR

164 ratio [OR], 0.20 [95% CI, 0.13 to 0.31]) and preemptive strategies (OR, 0.28 [CI, 0.11 to 0.69]) redu

165 Universal prophylaxis and preemptive strategies are beneficial in preventing CMV o

166 Prophylactic and preemptive strategies are used to prevent cytomegaloviru

167 Preemptive strategies should consider it for safety usag

168 Recommendations address prophylactic and preemptive strategies to minimize PTLD development, incl

169 VGCV prophylactic and preemptive strategies were compared in renal transplant

170 d for antiviral therapy and refining current preemptive strategies.

171 atic viremia could help significantly refine preemptive strategies.

172 higher for the prophylactic compared to the preemptive strategy (OR = 6.21; 95% CI, 2.55-15.20; P <

173 ograms used universal prophylaxis (UP), 8.7% preemptive strategy (PE), and 52.2% hybrid strategy.

174 this study, we have successfully developed a preemptive strategy for tissue protection using an adeno

175 ffects (leukopenia and neutropenia) than the preemptive strategy.

176 more frequent with prophylaxis than with the preemptive strategy.

177 The success of this preemptive strike implies a central role for B cells in

178 r preparing second generation analogues as a preemptive strike to such resistance strategies.

179 This preemptive study will aid in the interpretation of resis

180 ia in Plasmodium falciparum, which calls for preemptive surveillance of the African parasite populati

181 ive result(s) occurred in tests performed as preemptive surveillance only.

182 Such "preemptive" synthesis of hsps is sufficient to prevent i

183 close proximity to the carbocation and cause preemptive termination through elimination.

184 ble type B dissection with suitable anatomy, preemptive TEVAR should be considered to improve late ou

185 tionally, hAAT treatment may be considered a preemptive therapeutic measure for individuals who are a

186 By utilizing a preemptive therapeutic strategy with VGCV targeted only

187 allenges remain for defining indications for preemptive therapies and integrating novel and conventio

188 a major challenge to define indications for preemptive therapies for PTLD and to integrate novel the

189 ed that the predictive nomogram would permit preemptive therapies or allocation decisions based on th

190 was significantly higher in recipients under preemptive therapy (38.7% vs. 11.0%, P<0.0001), with the

191 ediate (D+/R+) CMV risk (n = 82) compared to preemptive therapy (n = 47) had no significant effect on

192 LT recipients managed with ganciclovir-based preemptive therapy (PET).

193 D+/R+ recipients with preemptive therapy also had the highest rate of CMV dise

194 55.6% of the patients with CMV treated with preemptive therapy and 49.8% of those without CMV infect

195 A preemptive therapy approach deserves further study.

196 risk R-/D+ patients, when followed using the preemptive therapy approach had no significant differenc

197 Prophylaxis and preemptive therapy are attractive strategies for this se

198 vs. 30.1 +/- 4.7 mL/min per 1.73 m(2) in the preemptive therapy cohort, P < 0.05).CMV replication was

199 for patients with CMV infection who received preemptive therapy compared with those who never develop

200 ents who received transplants in the current preemptive therapy era (n = 233) showed only lymphopenia

201 mized controlled trial of prophylaxis versus preemptive therapy for CMV.

202 The efficacy of valganciclovir used as preemptive therapy for cytomegalovirus (CMV) disease in

203 n (pp65) antigenemia (pp65emia) for starting preemptive therapy have not been well established.

204 cal trial to determine the clinical value of preemptive therapy in SMM.

205 economic merit of universal prophylaxis and preemptive therapy in the management of cytomegalovirus

206 The preemptive therapy of cytomegalovirus (CMV) reactivation

207 The effect of preemptive therapy on indirect sequelae associated with

208 ganciclovir recipients versus 21% of placebo-preemptive therapy recipients (treatment difference, -0.

209 Defining criteria for preemptive therapy remains a challenge.

210 Antigenemia-directed valganciclovir as preemptive therapy seems to be effective for the prevent

211 used drugs and diagnostics, ways to optimize preemptive therapy strategies with quantitative polymera

212 countries using no CMV prevention, and more preemptive therapy used in Asia.

213 Comparing preemptive therapy versus prophylaxis in D+/-/R+ patient

214 MV infection under universal prophylaxis and preemptive therapy was determined among 653 R+ patients

215 Thirteen years of outcome with the use of preemptive therapy were assessed in a cohort of 216 cons

216 h antigenemia who received valganciclovir as preemptive therapy were compared with 26.2% (21/80) of t

217 Thus, universal prophylaxis dominates over preemptive therapy with a cost saving of $27,967 for 1 Q

218 were allowed to break the blind and receive preemptive therapy with caspofungin.

219 of EBV/PTLD as well as being used to inform preemptive therapy with reduction of immunosuppression,

220 evidence of EBV reactivation and potentially preemptive therapy with rituximab.

221 Two patients received preemptive therapy with valganciclovir for individual ep

222 kinetics of the decrease in HCMV load after preemptive therapy with VGCV in 22 solid-organ transplan

223 Preemptive therapy with VGCV provides control of HCMV re

224 Using a risk threshold of 50%, preemptive therapy would have been prescribed for 8.4% o

225 e [D-/R+]; 146 receiving prophylaxis and 150 preemptive therapy).

226 oidentical (haplo)-HSCT recipients receiving preemptive therapy, among whom the rate was 14.5%.

227 % using only universal prophylaxis, 21% only preemptive therapy, and 33% a hybrid combination depende

228 Antiviral toxicity may be decreased with preemptive therapy, but effectiveness for CMV prevention

229 he current era of effective prophylactic and preemptive therapy, cytomegalovirus (CMV) is now a rare

230 ter transplant for universal prophylaxis and preemptive therapy, respectively.

231 Compared with preemptive therapy, universal prophylaxis incurred $1464

232 patients deserves investigation of BG-driven preemptive therapy.

233 prevention can be achieved by prophylaxis or preemptive therapy.

234 trials to evaluate the role of risk directed/preemptive therapy.

235 biweekly monitoring with a serum CMV PCR for preemptive therapy.

236 for early detection and prompt initiation of preemptive therapy.

237 996 to 2000 who received oral ganciclovir as preemptive therapy.

238 mpared with polymerase chain reaction-guided preemptive therapy.

239 .74; P = .003; Q = 48.10; I(2) = 75.1%) than preemptive therapy.

240 revent CMV include universal prophylaxis and preemptive therapy; each has its merits, and will be com

241 of inflammation that is induced by grafting (preemptive tolerance).

242 of vasopressor medications, and avoidance of preemptive transfusions of fresh frozen plasma.

243 mong 8,053 patients, 1117 (13.9%) received a preemptive transplant (66.9% from LD, 33.1% from DD).

244 own how race/ethnicity and poverty influence preemptive transplant access in pediatric.

245 T1DM population, short-term mortality after preemptive transplant is similar between LDK and SPK.

246 ) have been performed selectively to offer a preemptive transplant option for simultaneous pancreas-k

247 irst posttransplantation month were lower in preemptive transplant recipients than in patients on dia

248 58 on dialysis before transplantation and 14 preemptive transplant recipients) at baseline, on day 15

249 Future efforts to promote equity in preemptive transplant should address the critical issues

250 Blacks were 22% less likely to receive a DD preemptive transplant versus whites (RR = 0.78, 95% CI:

251 % CI: 0.35-0.67) less likely to receive a LD preemptive transplant versus whites.

252 Adjusted risk ratios for preemptive transplant were calculated using multivariabl

253 nt racial/ethnic disparities in access to LD preemptive transplant where blacks were 66% (RR = 0.34;

254 oved survival (P=0.08) among recipients of a preemptive transplant.

255 ) score could enable earlier and potentially preemptive transplantation (preKT).

256 incidence of living donor or deceased donor preemptive transplantation among all black, white, and H

257 Patient survival associated with preemptive transplantation among T1DM recipients was exc

258 Prior preemptive transplantation and graft loss after 5 years

259 the strong association between knowledge of preemptive transplantation and predialysis referral, thi

260 Preemptive transplantation avoids unnecessary dialysis a

261 nety-one subjects (46%) had been informed of preemptive transplantation before referral, and 80 (41%)

262 ld be applied to patient education regarding preemptive transplantation early after the diagnosis of

263 g-term dialysis and, if possible, conducting preemptive transplantation may represent the best strate

264 Preemptive transplantation results in excellent patient

265 Benefits and risks of preemptive transplantation vary between primary and seco

266 Preemptive transplantation was associated with a lower m

267 Preemptive transplantation was beneficial when first tra

268 analysis, among other factors, knowledge of preemptive transplantation was highly associated (odds r

269 The benefits of preemptive transplantation were evident in all patients

270 Preemptive transplantation with an extended criteria or

271 Recipient gender, preemptive transplantation, and time-varying terms for t

272 ody mass index, creatinine level, donor age, preemptive transplantation, deceased donor, early reject

273 as patient education regarding the option of preemptive transplantation.

274 odies, cold ischemia time, living donor, and preemptive transplantation.

275 A center's proportion of preemptive transplants (odds ratio [OR], 0.83; per 5% in

276 ent discontinued the study drug and received preemptive treatment against CMV infection.

277 recommend CMV prophylaxis or screening with preemptive treatment for all high risk recipients.

278 the potential advantage of prophylactic over preemptive treatment in high-risk patients and highlight

279 ther frequent monitoring of EBV DNA to allow preemptive treatment is truly of value in patients after

280 ys to attenuate cardiac disease in elders by preemptive treatment of age-related defects, in contrast

281 Preemptive treatment of mice with anti-IL-6R or anti-IL-

282 be used to enable the prompt rather than the preemptive treatment of PTLD.

283 us (SLE), but their utility as biomarkers in preemptive treatment to prevent flares remains a subject

284 actors and effectiveness of culture-directed preemptive treatment were evaluated via a Cox-proportion

285 kinetics of viremia and toxicities following preemptive treatment with and brincidofovir in children

286 s suggest a unique therapeutic potential for preemptive treatment with anti-TNF antibody to prevent s

287 the above-mentioned signs and symptoms, and preemptive treatment with dexamethasone should be starte

288 Preemptive treatment with SCP1 also upregulated agrin, t

289 Preemptive treatment with the TNF antagonist etanercept

290 s, and the effectiveness of culture-directed preemptive treatment, are not well known.

291 Parasitemia was successfully managed with preemptive treatment.

292 strategies for prophylaxis, monitoring, and (preemptive) treatment of CMV.

293 ion for sensory consequences of movement and preemptive updating of spatial representations.

294 These results indicate that preemptive vaccine updates may improve influenza vaccine

295 HA specificity can guide the development of preemptive vaccines and therapeutic monoclonal antibodie

296 Graft loss occurred in 7 vs. 4 patients on preemptive versus prophylactic therapy (P>0.05).

297 years was similar in the two groups (53+/-23 preemptive vs. 52+/-20 ml/min nonpreemptive; P=0.37).

298 om starting dialysis to waitlisting and less preemptive waitlisting included Medicare insurance for p

299 ng in poverty, being a non-U.S. citizen (for preemptive waitlisting), Medicaid insurance, waitlisted

300 to their lower socioeconomic status and less preemptive waitlisting.