ライフサイエンスコーパス: preferably

1 t material before the patient is discharged (preferably 24-72 hours after surgery).

2 s easily explained by the fact that Cu(I) is preferably 4-coordinate and Cu(II) and Zn(2+) are 5-coor

3 sing the consensus motif GHFGGXY, where X is preferably a hydrophobic amino acid, was shown previousl

4 z (z = 3 +/- 1; W = A or T; X = any base but preferably a purine).

5 ly the wild type and an alternative residue, preferably a smaller one with similar properties.

6 side chain was replaced with an alkyl group, preferably a tert-butyl group (10h).

7 rption data suggest that a PA fiber does not preferably absorb polar compounds (with permanent dipole

8 alyzed in a quantitative manner to establish preferably accumulated fragments.

9 We find that PS preferably accumulates at cell tips and defines a gradie

10 Interestingly, we found that ART preferably accumulates in the lysosomes and is able to a

11 candidates are urgently needed, which should preferably act via novel mechanisms.

12 ce for alpha4 over alpha(1,2,6)-subunits and preferably activated alpha4beta1delta (EC(50) = 140 nM)

13 Native alpha-conotoxins preferably adopt the globular connectivity, and previous

14 ick-tufted neurons reliably increase spiking preferably after passive touch.

15 S without template realignment and inserting preferably an A opposite the abasic site (A rule).

16 ylactic episode, follow-up with a physician, preferably an allergy/immunology specialist, is importan

17 ution with either low-contrast detection or, preferably, an off-line noise metric (pixel SD) provides

18 ally the Pro-Y bond in dipeptides where Y is preferably Arg or Lys.

19 ermanent dipole moment); instead, it absorbs preferably aromatic compounds.

20 r activation-induced transcription and binds preferably as a heterodimer with ATF-2.

21 consistent with a model in which hTS exists preferably as an asymmetric dimer with one subunit in th

22 and found that Rin1, a Rab5 exchange factor, preferably associated with Rab5A.

23 uring the process, a ubiquitin ligase, Itch, preferably associates with BFRF1 and is required for BFR

24 py should be performed at least 3 weeks, and preferably at 6 to 8 weeks, after chemotherapy or chemoi

25 tatus assessed by bone mineral densitometry, preferably at a site containing cortical bone, such as t

26 ParB also nicks supercoiled plasmid DNA preferably at sites with potential single-stranded chara

27 )X1-6pY (where X is any amino acid) with V/A preferably at the N terminus of the peptide.

28 low-power manipulation of the magnetization, preferably at ultrashort timescales, has become a fundam

29 e restricted to one procedure per day; (vii) preferably be authorized by first-person consent, though

30 Cancer vaccines should preferably be composed of multiple defined tumor Ag-spec

31 ensitive to radiometal modifications and may preferably be coupled with a (68)Ga-NODAGA chelator-radi

32 requirement, central venous catheters should preferably be inserted: a strategy associated with less

33 e myeloma, the second transplantation should preferably be performed before relapse and within 6 to 1

34 Confirmatory testing should preferably be performed by a reference laboratory with e

35 ed for all ascitic patients, and this should preferably be performed prior to the development of rena

36 ning clinical gene therapy trials and should preferably be tested directly in comparative studies.

37 tres with multidisciplinary teams and should preferably be treated in a specialised intensive care un

38 requires more sensitive techniques that can preferably be used at the single-cell level.

39 ministered early in the course of treatment, preferably beginning with cycle one or two of chemothera

40 munization Practices for all pregnant women, preferably between 27 and 36 weeks' gestation.

41 not uniformly wet the surface, but molecules preferably bind along directions parallel to the Si dime

42 The site of LPS binding means that ColN will preferably bind at the interface and thus position itsel

43 xtures at pH 5 indicated which species would preferably bind Cu(I) ions over forming the intramolecul

44 They preferably bind to the open state of the sodium channel

45 lude that these positively charged molecules preferably bind to the TCP locus, perhaps interacting wi

46 Hfq forms hexameric rings, which preferably bind uridine-rich RNA 3' ends on their proxim

47 likely possess strongD-stereoselectivity by preferably binding and incorporating D-dNTPs over unnatu

48 gion serves as the primary binding hot spot, preferably binding small tertiary amines.

49 This is consistent with the trianion of PGA preferably binding to the enzyme.

50 Molecular docking suggested that 3-NOP preferably binds into the active site of MCR in a pose t

51 the cobound cation (TBA(+) salts) receptor 1 preferably binds nitrate and nitrite over other anions,

52 M3 preferably binds peptides bearing an N-terminal formylme

53 The p47(phox) PX domain preferably binds phosphatidylinositol 3,4-bisphosphate (

54 SPR shows that cholera toxin preferably binds to gangliosides in the following sequen

55 rated with methods for population reduction, preferably biological control.

56 The exocyclic nitrogen atom preferably bonds to electrophiles and its electron-donat

57 and C-terminal residues of MBD1-c but HDAC3 preferably bound to the C-terminal region.

58 MPs, the bias of certain residue types to be preferably buried or exposed is proposed as a criterion

59 rotection following a single administration, preferably by a noninvasive route, and be safe even in t

60 ned either by a prior hydration mechanism or preferably by electrostatic effects on the formation of

61 ogy to improve efficacy and reduce toxicity, preferably by integrating a biologic approach to this cu

62 y mortality, stroke, and/or total mortality, preferably by randomized, double-blind, placebo-controll

63 g of a high carbohydrate, high protein diet, preferably by the enteral route; and early institution o

64 Prompt delivery, preferably by the vaginal route, is vital for good mater

65 Correction of MR, preferably by valve repair rather than replacement, is c

66 a result, the analysis of liquid samples is preferably carried out by analyzing dried residues or by

67 oichiometry of neurotransmitter receptors is preferably carried out in a mammalian expression system

68 lost insulin-producing cells with new ones, preferably cells from a well-characterized and unlimited

69 h the physiochemical consensus [hydrophobic][preferably charged][small or hydrophobic, but not tiny][

70 all or hydrophobic, but not tiny][IL][polar, preferably charged][small, but not charged][hydrophobic,

71 ere anchored on amorphous magnetic particles preferably chosen to capture OP-AChE from the sample mat

72 ssigned since the disulfide bonds were still preferably cleaved over the glycosidic cleavages under E

73 structure-directing quaternary ammonium ions preferably close to the charge center, unless steric shi

74 More prospective studies are needed, preferably combining BCRP protein or mRNA quantification

75 vision that services should be inclusive and preferably community based.

76 suppressing GLV production, as caterpillars preferably consumed leaf tissue from plants that had not

77 lots for spatially representative data sets, preferably containing >1000 determinations.

78 Additional work, preferably controlled prospective studies, needs to be p

79 mapped genes be grouped into a few operons, preferably coregulated in the target genome.

80 ilute polymer solution, electroosmotic flow (preferably countercurrent to the direction of cell elect

81 That domain binds preferably Cu(II) ion forming a stable complex.

82 ng an extensive questionnaire, they entered (preferably daily) their symptoms of eyes, nose, and lung

83 nstrate that the L. pneumophila protein SidD preferably deAMPylates Rab1.

84 eously increase yields while maintaining, or preferably decreasing, applied N to maximize the nitroge

85 llenges, require the assistance of catalysts preferably deposited on conducting or semiconducting sur

86 Nowadays one can preferably design electrocatalysts based on the deep the

87 olymorphisms is carried out using a cross of preferably distant populations.

88 vidual cells can be oriented arbitrarily but preferably either horizontally or vertically relative to

89 lations in posterior/dorsal auditory regions preferably encode coarse spectral information with high

90 lations in anterior/ventral auditory regions preferably encode fine-grained spectral information with

91 Mechanistically, muEPIT preferably enhanced IgG2a production suggesting TH1-bias

92 n spectroscopy, etc., show that Yb(3+) would preferably enter into the zeolite-Y pores and introducti

93 hiazole-2-amine indicated that these species preferably exist in the iminic state.

94 Continued and preferably expanded participation of blood centers in th

95 smic reticulum, is recently discovered to be preferably expressed on the surface of stressed cancer c

96 We observed that mHTT was preferably expressed within the anterior horn of the gra

97 ndation is to consume 2 fish meals per week (preferably fatty fish).

98 FOS molecules with a low DP are preferably fermented by beneficial microbiota than inuli

99 of the corresponding polyphenol glycosides, preferably for their subsequent isolation and purificati

100 ag' for early detection of breast cancer or, preferably, for detection of premalignant changes.

101 Its side chain atoms preferably form hydrogen bonds with main chain atoms.

102 e visualization, dissemination and curation, preferably from a centralized platform.

103 to three blood cultures should be performed, preferably from a peripheral vein, without interval betw

104 must use the highest-quality validated data, preferably from a prospectively maintained clinical data

105 equires models demonstrating EP decline, and preferably, genetically distinct strains that vary in pa

106 compounds favoring activation of G proteins (preferably Go) over beta-arrestin recruitment at dopamin

107 f such a vast compilation requires a simple (preferably graphical) means to differentiate between com

108 numt alignments must be at least 500 bp, and preferably >1 kb in length, to accurately reconstruct ho

109 The "science of intentional change" should preferably have a terminology that distinguishes between

110 It is recommended to use multiple assays (preferably hemolytic, anti-Gal, and anti-endothelial cel

111 ty that enables assessing variable sets for, preferably high, predictivity.

112 stringency ensures that all targets will be preferably hybridized at equilibrium.

113 The intrinsic Sac3(WT) phosphatase activity preferably hydrolyzed PtdIns(3,5)P2 in vitro, although t

114 only in the wine but also in grape berries, preferably if the determination of the delta(18)O value

115 our results suggest that early intervention, preferably in a high-level intensive care facility with

116 ials will allow better selection of therapy, preferably in an individualized fashion, potentially tra

117 g pathway may be of therapeutic value in CF, preferably in conjunction with antiprotease treatment.

118 t genomic regions surrounding specific SNPs, preferably in haploid form.

119 ice-changing evidence requires confirmation, preferably in multi-institutional clinical trials.

120 the community setting should be established (preferably in parallel to randomized trials) so that tre

121 ting cognitive disorders of various origins, preferably in patients with unsatisfactory responses to

122 Obtaining isolates of these targets, preferably in pure cultures, is crucial for advancing un

123 ligands investigated here are found to bind preferably in similar ways close to the active site.

124 Here, we show that APE1, preferably in the acetylated form, stably interacts with

125 igh-quality experimental protein structures, preferably in the bound conformational state.

126 medical and social intervention strategies, preferably in the context of a multidisciplinary team.

127 ent of interest and patients not so treated, preferably in the context of a randomized study.

128 ne, a fluoroquinolone antibiotic, is applied preferably in veterinary medicine, for stock breeding an

129 there is a trend for healthy food products, preferably incorporating natural bioactive ingredients,

130 intervention with antiinflammatory therapy, preferably inhaled corticosteroids, in children who have

131 We found that both compounds preferably inhibit the open-channel state, although BDZ-

132 In mammalian NaVs, JZTx-27 preferably inhibited the inactivation of NaV1.5 by targe

133 Since DNA transposons preferably insert near genes, this is correlated with in

134 ltiple nanoseconds suggest that the peptides preferably interact with vacant sites of the face-center

135 p67phox preferably interacted with inactive Galphai.

136 scriptional repressor (mSin3B), whereas RFX1 preferably interacts with HDAC1 and mSin3A.

137 Preferably, it should only be performed in instances whe

138 These nontoxic D-amino acids preferably label the sites of active PG synthesis, there

139 ng a strained disulfide from asparagusic or, preferably, lipoic acid and a guanidinium cation polymer

140 plus radiotherapy with or without resection (preferably lobectomy) are options for patients with stag

141 We report that Par-4 is a synaptic protein preferably localized in postsynaptic density (PSD).

142 years, or when MRI severity scores were low (preferably </=17).

143 racteristics of the virus in cultured cells (preferably lung cells) from the same species.

144 than a phenylalanine residue at P3 and P3', preferably medium-sized amino acids in the range from va

145 bust to many environments, easy to use, and, preferably, mobile.

146 </=10(-5)), if sufficient cells (>4 x 10(6), preferably more) are evaluated.

147 nce of having results from at least one, and preferably more, large, randomized intervention trial be

148 with more-sensitive tests for T. vaginalis, preferably NAATs, if microscopy is negative.

149 is domain is required to be hydrophilic, but preferably negatively charged, in order to present the c

150 o each of the canonical bases with little or preferably no destabilization of the overall duplex.

151 This includes methods for the preferably nondestructive quantification of the number o

152 fore, it is critical to develop a sensitive, preferably noninvasive, method for detecting the disease

153 Biomarkers, preferably noninvasive, that predict asthma inception in

154 at (i) effects of dietary Zn exposure should preferably not be investigated in isolation from waterbo

155 preferably not polar][hydrophobic, not tiny, preferably not polar].

156 , but not charged][hydrophobic, not charged, preferably not polar][hydrophobic, not tiny, preferably

157 Furthermore, it should preferably not rely on tumor-specific surface markers, a

158 tended target, while binding only weakly (or preferably, not at all) to non-target sequences which ma

159 or our view that a single, standardized (and preferably observational) screening tool for delirium sh

160 that serine 23 phosphorylation of caveolin-2 preferably occurs in detergent-resistant membranes (DRMs

161 wounds, obtain a post-debridement specimen (preferably of tissue) for aerobic and anaerobic culture.

162 o enhance the prospects for enteral autonomy preferably on autologous bowel.

163 uraged to receive combined-modality therapy, preferably on clinical trials with cautious, judicious m

164 e recommendations for adults should be based preferably on direct measurements of total daily energy

165 alytic activity against substrates with Arg, preferably, or Lys at the P1 position, comparable to try

166 CT imaging in epilepsy should perform ictal, preferably, or postictal scanning in combination with in

167 c Kidney Disease Epidemiology Collaboration, preferably, or the Modification of Diet in Renal Disease

168 nd pausing intervals, while the cell body is preferably oriented with its wide side toward the direct

169 ic linker and Zn(2) clusters that sorb CO(2) preferably over N(2) and H(2).

170 accines that can be administered simply and, preferably, painlessly without the need for timed booste

171 rmolytic deprotection of these carbonates is preferably performed in aqueous organic solvent at 90 de

172 The initial screening for nanotoxicity is preferably performed in vitro, but extrapolation to the

173 y located deep in the pelvis, procedures are preferably performed via a (robot-assisted) laparoscopic

174 prehensive assessment of exhaust toxicity is preferably performed with complete exhaust and with biol

175 y recommend CXR/MRI, whereas U.S. guidelines preferably point to CHCT/MRI in patients with head and n

176 iquid-polymer interfaces of the membrane are preferably polarizable.

177 atients with previous graft loss due to BKVN preferably post-BK viral clearance.

178 etect neoplasia at a surgically curative and preferably preinvasive stage, i.e., dysplasia.

179 need to be synthesized, analyzed, and, most preferably, preserved.

180 Additional investigations, preferably prospective studies, are needed to validate o

181 Overall, depletional induction (preferably r-ATG) appears to offer the greatest benefits

182 ibitors seem different, but further studies, preferably randomized trials, are needed to fully unders

183 gibility criteria, must have an appropriate, preferably randomized, control group, and must be design

184 Although M3-restricted CTLs preferably recognize N-formylated epitopes, i.e., those

185 d little evidence that the former population preferably recognizes self-antigens as agonists.

186 XA1 reprograms both AR and GATA2 cistrome by preferably recruiting them to FKHD-containing genomic si

187 aptation of treatment to improve outcome and preferably reduce toxicity.

188 omes among populations while maintaining, or preferably reducing, the overall costs of care.

189 ynamics simulations performed, and that ions preferably remain in S1 and S4.

190 Tumors were preferably removed by simple enucleation, or if not feas

191 ated that adjacent fluorine substituents are preferably removed.

192 ngs establish that a key UPR target GRP78 is preferably required for pathophysiologic conditions, suc

193 n first group of polyphenol compounds, which preferably requires low temperature followed by rapid dr

194 sponse to treatment suggesting that pH-metry preferably should be extended to 48 hours.

195 Varicella vaccine preferably should be given to children at the same time

196 Under stress, RB is preferably spliced in neurons to produce the neuroprotec

197 Those with an acceptable benefit, preferably symptom remission, from any particular step c

198 n larger ones (550nm), while the latter were preferably taken up by M cells in the follicle-associate

199 This knowledge predicts that DAHP would preferably target GTPCH in tissues with abundant GFRP.

200 e variety of vital biological processes were preferably targeted by lysine 2-hydroxyisobutyrylation,

201 he importance of early smoking cessation and preferably the avoidance of smoking.

202 Estimates of the number, and preferably the identity, of species that will be threate

203 r one time-to-event outcome from each trial, preferably the primary outcome.

204 lin binds directly to lipoprotein receptors, preferably the very low-density lipoprotein receptor (VL

205 Preferably, the anode off-gas stream is used to sweep th

206 Preferably, the entire process should be computationally

207 Preferably, the severity level of urinary incontinence s

208 ervices medical directors and trauma chiefs, preferably those based at the main trauma centers or pub

209 A minimum of four specimens, preferably those that are nonfragmented and that sink, s

210 Topical corticosteroids, preferably those with reduced side effects, are availabl

211 ons support that this cycloaddition proceeds preferably through a stepwise mechanism.

212 gh either evidence-based dosing nomograms or preferably through the use of dosing software supplement

213 riable quotas following current practice or, preferably, through a market mechanism whereby fish are

214 binding studies showed that the domain binds preferably to [Ser-2 + Ser-5]-phosphorylated CTD peptide

215 -1 and 15-LOX-2 oxygenate 2-AG comparably or preferably to arachidonic acid.

216 n its methyl-CpG-binding domain, which binds preferably to G.T mispairs in a methylated CpG site.

217 tiapoptotic proteins Mcl-1 and Bcl-x(L) bind preferably to the BH3-only proteins Bim, PUMA, and Noxa

218 The results indicated that hXBP-1 binds preferably to the CRE-like element GAT-GACGTG(T/G)NNN(A/

219 igens and cell fragments from E. coli bonded preferably to the fat particles within meat, and the siz

220 uman blood and BM, myeloid cells and B cells preferably took up more oligonucleotides than T cells.

221 itive detection of this dangerous infection, preferably transdermally and without sophisticated reage

222 ediate, Delta(1)-pyrroline-5-carboxylate, is preferably transferred to the P5CDH domain rather than r

223 ns ATP-dependent RNA helicase activity which preferably translocates in the 5'-->3' direction.

224 st volume restricted to less than thrice and preferably twice the CCC might be valuable in reducing t

225 l intervention, if needed, should be delayed preferably until an age when the child is fully grown.

226 Clinicians should preferably use age-appropriate LogMAR acuity tests, and

227 When expressed in heart tissue, BAH/humbug preferably use the first exon and often the fourth exon

228 r immune stimulation short RNA isoforms were preferably used.

229 d menaquinones with similar efficiencies and preferably uses NADPH as an electron donor.

230 al regimens to standard treatments are made (preferably using an intermediate end point) by carefully

231 growth-monitoring parameters in combination, preferably using computerized screening algorithms that

232 compared with primaquine-based combinations, preferably using MB in an improved pediatric formulation

233 nstruction of translational reporters would, preferably, utilize genomic clones, containing the compl

234 Here we show that TpeL preferably utilizes UDP-N-acetylglucosamine (UDP-GlcNAc)

235 nd that the detection threshold be known and preferably very small relative to total MRLC concentrati

236 Stopping before age 40 years (and preferably well before age 40 years) avoids more than 90

237 resection including at least 15 lymph nodes, preferably with 5 cm of grossly normal in situ proximal

238 ucation dealing with pediatric rheumatology, preferably with a lecture format in their home communiti

239 ion and hydroamination in a cascade process, preferably with a single catalyst, would allow rapid acc

240 tory experiments must be carefully designed, preferably with a smaller type I and II error rate than

241 Regular removal of the biofilm, preferably with a toothpaste containing fluoride, delays

242 further suggest that TTR tetramers interact preferably with Abeta aggregates rather than Abeta monom

243 rs to initiate sgRNA synthesis with purines, preferably with adenylates, and is able to initiate synt

244 d analyze the resulting data quantitatively, preferably with automated tools.

245 with tuneable amounts of functional groups, preferably with consecutive insertions of polar monomers

246 created an urgent need for novel antibiotics preferably with entirely new mechanisms of action.

247 s and comprise drugs from different classes, preferably with Food and Drug Administration approval.

248 he short DNA repeats seemed to be associated preferably with genes.

249 mia and preserves awareness of hypoglycemia, preferably with little or no symptomatic or even asympto

250 is should include neuroimaging of the brain, preferably with MR, together with the somatostatin recep

251 Neuroimaging, preferably with noncontrast helical computed tomography,

252 cles and results from large clinical trials, preferably with outcomes from many years of follow-up we

253 ectable as an adduct with protonated ethers, preferably with protonated tetrahydrofuran.

254 the TTAAAA consensus site toward the 3' end, preferably within 15-16 base pairs.

255 preventing trichinellosis when given early, preferably within 6 days.

256 as soon as the patient's condition permits, preferably within 6 weeks.

257 recommend early mobilization of stem cells, preferably within the first 4 cycles of initial therapy,

258 skin layers in a stable and functional form, preferably without painful administration.

259 are needed for the treatment of asthma, but preferably without the systemic adverse effects of gluco

260 requires more sensitive techniques that can preferably work on single cells.

261 s, while those with electron-donating groups preferably yield indole products with substituted phenyl

262 uction of chromanone 18 at lower temperature preferably yielded (+/-)-1.