ライフサイエンスコーパス: pregnancy

1 cy) or without (107 pregnant and 57 planning pregnancy).

2 ing of women without epilepsy (2.51% in 2154 pregnancies).

3 terine endothelial cell proliferation during pregnancy.

4 nown about bone mineral density (BMD) during pregnancy.

5 and acellular pertussis immunisation during pregnancy.

6 to lower glucocorticoid levels during obese pregnancy.

7 quantified serially in early, mid-, and late pregnancy.

8 changes in pregnant women at 26-28 weeks of pregnancy.

9 who underwent endoscopy just before or after pregnancy.

10 erview, which took place in the 16th week of pregnancy.

11 ed only in the first trimester or throughout pregnancy.

12 ental development and maternal adaptation to pregnancy.

13 pression of GPR64 in the uterus during early pregnancy.

14 tiretroviral prophylaxis or treatment during pregnancy.

15 d with a serotonin reuptake inhibitor during pregnancy.

16 ng evidence that these effects persist after pregnancy.

17 , meconium peritonitis and abdominal ectopic pregnancy.

18 tely perturb maternal-fetal tolerance during pregnancy.

19 clinically used for cervical ripening during pregnancy.

20 rmline gene editing that culminates in human pregnancy.

21 ported consequences of such infection during pregnancy.

22 s index, smoking and maternal smoking during pregnancy.

23 15 birth rates to estimate infections during pregnancy.

24 l activity, smoking, and stress during early pregnancy.

25 e of insufficient safety data for use during pregnancy.

26 with blood pressure measurements throughout pregnancy.

27 ng all women with malaria are treated during pregnancy.

28 estational age and followed until the end of pregnancy.

29 tpatient clinic within the first 18 weeks of pregnancy.

30 t participants and for participants planning pregnancy.

31 undability among women who were planning for pregnancy.

32 stribution of the higher percentiles in late pregnancy.

33 oimmunity and complications during and after pregnancy.

34 in infants with confirmed Zika virus during pregnancy.

35 pring of mothers that abuse marijuana during pregnancy.

36 unting of the corticosterone response during pregnancy.

37 tions) that were available before and during pregnancy.

38 the endometrial stromal cells for successful pregnancy.

39 ose intolerance or insulin resistance during pregnancy.

40 oglobin concentrations are measured in early pregnancy.

41 ur recalls that were administered throughout pregnancy.

42 were diagnosed with dengue infection during pregnancy.

43 xposure in the first trimester or throughout pregnancy.

44 ure maintenance of uterine blood flow during pregnancy.

45 confidence interval [CI], .28-.48) per 1000 pregnancies.

46 s measured on a typical day of participants' pregnancies.

47 of revaccination over the course of multiple pregnancies.

48 d fetal growth restriction (FGR) complicated pregnancies.

49 d in preeclamptic compared with normotensive pregnancies.

50 -blind trial of vitamin D supplementation in pregnancy (400, 2000, or 4000 IU/d).Treatment had no sig

51 (10% decrease), implantation (31%), clinical pregnancy (41%), and live birth (38%).

52 6.7% (95% CI, 94.1%-99.3%) for women who had pregnancy 6 months or more after diagnosis of breast can

53 to detect abnormalities at an early stage of pregnancy, a GO-peptide-based surface plasmon resonance

54 elative risks (ARRs) for adverse outcomes of pregnancy according to endoscopy status using 1,589,173

55 fistula recurrence, associated outcomes, and pregnancy after successful fistula closure.

56 7.5% (95% CI, 86.5%-88.4%) for women with no pregnancy) (age-adjusted HR, 0.22; 95% CI, 0.10-0.49; P

57 In comparison with women with at least 2 pregnancies, all of which were delivered at term, women

58 alyses of registration for drug abuse during pregnancy among Swedish women born between 1980 and 1990

59 neutrophil signature increased linearly with pregnancy, an immune state of increased susceptibility t

60 Here, we show that pregnancy analgesia can produce a complete cessation of

61 Miscarriage affects 20% of pregnancies and maternal infections account for 15% of

62 whether in asymptomatic women with singleton pregnancies and no prior spontaneous preterm birth but w

63 were significantly different between normal pregnancies and those complicated by severe FGR.

64 ttending physicians during their most recent pregnancy and 393 (25.5%) practiced in a procedural fiel

65 cy and reassessed them at 28 (+/-4) weeks of pregnancy and 8 (+/-4) weeks postpartum.

66 completed interviews during their partner's pregnancy and 9 months after the birth of their child.

67 ciation between influenza vaccination during pregnancy and ASD.

68 sants in each individual trimester or before pregnancy and ASDs.

69 overweight have not had sufficient impact on pregnancy and birth outcomes, which suggests that the fo

70 was observed between maternal B12 levels in pregnancy and birth weight, but B12 deficiency (<148 pmo

71 online questionnaire regarding the impact of pregnancy and childbearing.

72 Within the Pregnancy and Childhood Epigenetics (PACE) Consortium, w

73 hat maternal stress and/or depression during pregnancy and early life are associated with recurrent w

74 nd early career, improving the experience of pregnancy and early parenthood for all cardiologists may

75 ons, particularly those studying the role of pregnancy and early-life exposures on later-in-life heal

76 ived urine samples taken from mothers during pregnancy and from their children when 6-12 y old, adjus

77 ight (8%) of 104 control participants during pregnancy and in 23 (44%) of 52 CGM participants and fiv

78 leptin and adiponectin concentrations during pregnancy and infant birth weight (BW) is still poorly c

79 , RES supplementation of HFD-fed dams during pregnancy and lactation promoted white adipose browning

80 upplementation with PQQ, particularly during pregnancy and lactation, protects offspring from WD-indu

81 ol) or 70% of the control ad libitum diet in pregnancy and lactation, which were growth restricted at

82 Rates of ongoing pregnancy and live births were higher among women who un

83 Both maternal smoking during pregnancy and low birth weight have been implicated in i

84 female donors with and without a history of pregnancy and mortality of red blood cell recipients.

85 ntinue to recommend the women with HIV avoid pregnancy and neglect to invite partners to participate

86 nosis of epilepsy as well as obesity-related pregnancy and neonatal complications were based on infor

87 ng 7 adverse obstetrical outcomes throughout pregnancy and occurring before hospital discharge.

88 of congenital heart defects (CHDs) later in pregnancy and on the outcome of fetuses and children bor

89 gnificantly reduced malaria incidence during pregnancy and placental malaria risk.

90 its interaction with the hormonal changes of pregnancy and postpartum.

91 ssociation between phthalate exposure during pregnancy and preterm birth by oxidative stress.

92 ecticut and Massachusetts before 17 weeks of pregnancy and reassessed them at 28 (+/-4) weeks of preg

93 confers protection from autoimmunity during pregnancy and represents a potential target for future t

94 amine the association between smoking during pregnancy and severe mental illness in offspring, adjust

95 The association between malaria in pregnancy and stillbirth has yet to be comprehensively q

96 3'UTR-LAV) prevent viral transmission during pregnancy and testis damage in mice, as well as infectio

97 NS-LNS), 2) iron and folic acid (IFA) during pregnancy and the first 3 mo postpartum and LNSs for the

98 ectiveness trial with 4 arms: 1) LNSs during pregnancy and the first 6 mo postpartum and LNSs for the

99 n association between maternal stress during pregnancy and TL in the offspring.

100 most entirely of women who were obese before pregnancy and was associated with a >2-fold increase in

101 men (N = 86) who were recruited during early pregnancy and whose offspring were born after 34 weeks'

102 ociations with maternal dispensations before pregnancy and with paternal first-trimester dispensation

103 Lamotrigine (2.31% in 4195 pregnancies) and levetiracetam (1.77% in 817 pregnancies

104 ; 54 women met criteria for P-SCAD (4 during pregnancy) and they were compared with 269 women with NP

105 ey seek care later, make fewer visits during pregnancy, and receive fewer components of care than old

106 ), a state of transient hyperglycemia during pregnancy, and retinal microvascular changes in pregnant

107 ngly associated with maternal smoking during pregnancy, and thus their association with EA could be d

108 factors (number of live births, age at first pregnancy, and total reproductive duration [time from me

109 to 24 weeks or conception in women planning pregnancy, and was assessed in all randomised participan

110 is up-regulated in the decidua during early pregnancy, and women with recurrent miscarriage have low

111 ronutrient use during the first trimester of pregnancy appeared to be of particular importance for pr

112 Considerations for cardiac imaging in pregnancy are also discussed.

113 mega-3 PUFAs in the late-second trimester of pregnancy are associated with less weight retention at 1

114 Metabolic adaptations in early pregnancy are uncoupled from the circadian clock, wherea

115 o endoscopy status using 1,589,173 unexposed pregnancies as reference.

116 From a single study with pregnancies as the denominator, the incidence of materna

117 Pre-pregnancy assessment is important to identify patients w

118 Pregnancy-associated Plasmodium falciparum infection imp

119 illion 95% crI) of these 9.5 million (69.3%) pregnancies at risk of infection (and 53.4% [16.3 millio

120 ption, first and second trimester, and whole-pregnancy averages.

121 bese or exhibit excessive GWG, both high pre-pregnancy BMI and excessive GWG influence perinatal outc

122 gression tested the associations between pre-pregnancy BMI or GWG and length of gestation, birthweigh

123 To study the associations between early pregnancy body mass index (BMI) and rates of cerebral pa

124 , cohabitation with a partner, height, early pregnancy body mass index, smoking, year of delivery, ma

125 /ethnicity and BMI play an important role in pregnancy bone health.

126 ETATION: P falciparum and P vivax malaria in pregnancy both increase stillbirth risk.

127 The heart hypertrophies during pregnancy, but its metabolic adaptations, are not well u

128 ural estrogen synthesized exclusively during pregnancy by the human fetal liver and initially conside

129 Zika virus infection during pregnancy can cause congenital abnormities or fetal demi

130 Diabetes mellitus in early pregnancy can cause neural tube defects (NTDs) in embryo

131 opriately increased maternal hepcidin during pregnancy can compromise the iron availability for place

132 Prospective time-to-pregnancy cohort study (2008 to date of last follow-up i

133 rticipants in the Omega Study (n = 3,005), a pregnancy cohort study conducted in Washington State (19

134 the Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort, in Gomez Palacio, Mexico.

135 r and Child Cohort Study, a population-based pregnancy cohort, linked to the Norwegian Prescription D

136 ciated with the highest risk (10.93% in 2565 pregnancies) compared with the offspring of women withou

137 Interestingly, in some pregnancies complicated by preterm premature rupture of

138 g fetal origins of cardiovascular disease in pregnancy complicated by chronic fetal hypoxia.

139 STRACT: Chronic fetal hypoxaemia is a common pregnancy complication that may arise from maternal, pla

140 estational diabetes mellitus (GDM), a common pregnancy complication which has short-term and long-ter

141 hed a mouse model that provided evidence for pregnancy complications and placental anti-angiogenesis

142 isorder and GAD do not contribute to adverse pregnancy complications.

143 ant expression of host genes associated with pregnancy complications.

144 Malaria during pregnancy constitutes a large health problem in areas of

145 gnancies, urine from women with preeclamptic pregnancies contained a high ratio of podocin-positive t

146 es (pPROM), membranes heal spontaneously and pregnancy continues until term.

147 vere disease-related damage who should avoid pregnancy, counsel patients to conceive when disease has

148 the limited availability of ultrasound-based pregnancy dating to assess impacts on preterm birth and

149 dose, but revaccinating mothers during every pregnancy decreased incidence for these infants by 58%,

150 n infectious cause of fetal anomalies during pregnancy, development of a vaccine that prevents HCMV i

151 We identified all pregnancies ending in stillbirth and a random sample of

152 women with endoscopy <1 year before or after pregnancy, endoscopy during pregnancy was associated wit

153 ed from the circadian clock, whereas in late pregnancy, energy availability is mediated by coordinate

154 Periods of dynamic hormonal flux, including pregnancy, exacerbate the risk for affective disturbance

155 g for protection from the use of ITNs during pregnancy, expanding IPTp-SP to all women with >/=3 ANC

156 We identified 3052 pregnancies exposed to endoscopy (2025 upper endoscopies

157 d from day 5 of gestation, implicating early pregnancy factors, which was confirmed by reduced expres

158 e gland-containing adult FOXA2-deleted mice, pregnancy failed by day 10 in neonatal FOXA2-deleted mic

159 fic GATA2/GATA3 function could lead to early pregnancy failure.

160 During late pregnancy, female mice show no evidence of chronic pain

161 ht the importance of thyroid hormones during pregnancy for normal development of the fetal pancreas.

162 Despite the strong evidence indicating pregnancy for women with HIV results in a safe birthing

163 eligibility for outcome, at age 1 year) and pregnancy (gestation and each trimester).

164 KEY POINTS: Late gestation during pregnancy has been associated with a relatively high pre

165 ng cervical structure and composition during pregnancy has high potential for prediction of preterm b

166 aternal antidepressant medication use during pregnancy has previously been associated with adverse ou

167 sorder develop POI, however rare spontaneous pregnancies have been reported.

168 of inflammation, a significant proportion of pregnancies have evidence of inflammation without any de

169 nges associated with maternal smoking during pregnancy have been described in placenta and cord blood

170 were pooled (772331 patients) for the whole pregnancy (hazard ratio, 1.26; 95% CI, 0.91-1.74) or for

171 rturbed maternal insulin sensitivity in late pregnancy; hepatic insulin sensitivity was higher, where

172 s influence on pregnancy outcome varies with pregnancy history.

173 Rather, we find that the pregnancy hormone progesterone induces PDK4 (pyruvate de

174 We show that the phenomenon is dependent on pregnancy hormones (estrogen and progesterone), delta-op

175 eries at each week from 23 through 38, whole-pregnancy hot exposures increased delivery risk by 6-21%

176 utable low birthweight (mLBW) in unprotected pregnancies (i.e., those not using insecticide-treated n

177 Mothers were considered vaccinated during pregnancy if Tdap was received >/=14 days before deliver

178 lar to the effect of Tdap vaccination during pregnancy, immune responses of later-born infants born t

179 Over an 8-year study period, a total of 1283 pregnancies in 1208 women fulfilled the criteria for inc

180 tal oxygenation during normal and pathologic pregnancies in mice.

181 ased linkage study of 979,912 term singleton pregnancies in Scotland, United Kingdom, between 1992 an

182 Pregnancies in women of advanced maternal age (AMA) are

183 conducted a cohort study involving 1,325,563 pregnancies in women who were enrolled in Medicaid and w

184 ressivity and penetrance of malformations in pregnancies in women with diabetes remain poorly identif

185 e mothers had HIV infection diagnosed before pregnancy in 2002-2005 compared with 120 (51.5%) in 2010

186 damage and transmission to the fetus during pregnancy in different animal models.

187 with fetal CNS-damaging malformations during pregnancy in humans.

188 for a causal role of maternal smoking during pregnancy in offspring depression, rather observed assoc

189 INTERPRETATION: Use of CGM during pregnancy in patients with type 1 diabetes is associated

190 en synthesis needed for the establishment of pregnancy in the pig and may serve to regulate the proin

191 t that sex-specific life experiences such as pregnancy increase stroke risk.

192 educed Treg increase and a selective loss of pregnancy-induced protection, whereas reproductive succe

193 Nonphysiological hypoxia during early pregnancy induces CHD, but the underlying reasons are un

194 n pregnancy was prospectively collected in 2 pregnancy interviews and linked with assessments of acad

195 rial of intermittent preventive treatment in pregnancy (IPTp) in Uganda, dihydroartemisinin-piperaqui

196 During pregnancy, iron needs to increase substantially to suppo

197 Scar pregnancy is an extremely rare type of ectopic pregnancy

198 Zika virus (ZIKV) infection in pregnancy is associated with adverse fetal outcomes, suc

199 In particular, the implantation stage of pregnancy is considered a key window of susceptibility f

200 portance of treating cobalamin deficiency in pregnancy is considered.

201 The use of antiretroviral therapy during pregnancy is important for control of maternal human imm

202 Here, the effect of exposure during pregnancy is investigated in an agriculturally dominated

203 immune activation (MIA) via infection during pregnancy is known to increase risk for autism spectrum

204 Immune tolerance during human pregnancy is maintained by a range of modifications to t

205 uman cytomegalovirus (HCMV) infection during pregnancy is the major cause of congenital viral sequela

206 eclampsia, which affects approximately 5% of pregnancies, is a leading cause of maternal and perinata

207 PE), which affects approximately 8% of first pregnancies, is associated with faulty placentation.

208 ocytes and that elevated PDK4 levels in late pregnancy lead to inhibition of PDH (pyruvate dehydrogen

209 sion and that the combination of both during pregnancy leads to very high rates of subsequent diabete

210 onding risks of miscarriage, stillbirth, and pregnancy loss in a sensitivity analysis restricted to a

211 e confers no significantly increased risk of pregnancy loss, neonatal mortality, or malformation.

212 infection of partner(s)', 'Birth control and pregnancy management'.

213 them to a regional center with expertise in pregnancy management.

214 we meta-analysed the association between pre-pregnancy maternal BMI and methylation at over 450,000 s

215 In healthy human pregnancies, maternal hepcidin concentrations are suppre

216 s that compared siblings while adjusting for pregnancy, maternal, and paternal traits, first-trimeste

217 Licorice consumption during pregnancy may be associated with harm for the developing

218 associated with Zika virus infection during pregnancy may help guide communication, prevention, and

219 trointestinal and genital tracts and, during pregnancy, neonates are at risk of infection.

220 nal circulating vitamin D metabolites during pregnancy.Nested within a feeding study, 24 healthy preg

221 and 53.4% [16.3 million/30.6 million] of all pregnancies) occurred in settings with near-perfect SP c

222 y and antiepileptic drugs (AEDs) used during pregnancy on fetal growth and preterm delivery.

223 that the effect of malaria infection during pregnancy on the risk of low birthweight (LBW; <2,500 g)

224 sensitivity of 100% for infants infected in pregnancy or at least 4 weeks prior to testing, and a mo

225 during pregnancy that could lead to adverse pregnancy or developmental outcomes; however, these resu

226 This appears especially true during pregnancy or in individuals predisposed to autoimmunity.

227 mothers was not explained by obesity-related pregnancy or neonatal complications.

228 Neither vaccination during pregnancy or use of the larvicide pyriproxyfen was assoc

229 oring with CGM (108 pregnant and 53 planning pregnancy) or without (107 pregnant and 57 planning preg

230 r did the type, frequency, timing related to pregnancy, or applicator of pesticide used influence est

231 the vaginal microbiome and its influence on pregnancy outcome varies with pregnancy history.

232 in 71% of the women, with no relationship to pregnancy outcome.

233 the effects of disease activity, we examined pregnancy outcomes (preterm birth, stillbirth, small for

234 e determined and tested for association with pregnancy outcomes and PAM indicators using linear and l

235 HbAC and HbAS were not associated with other pregnancy outcomes or PAM indicators.

236 f biomass fuels has been linked with adverse pregnancy outcomes such as low birth weight, stillbirth,

237 s globally, monitoring for potential adverse pregnancy outcomes will be crucial.

238 ain how Ct infection could result in adverse pregnancy outcomes.

239 ydrogen sulfide donors are likely to improve pregnancy outcomes.

240 A high proportion of women start pregnancy overweight or obese.

241 ges, hematopoietic cells, and in the case of pregnancy, placental syncytiotrophoblast cells) and seve

242 on health, an integrated approach, including pregnancy prevention, planning, and preparation is neede

243 ears participating in the Western Australian Pregnancy (Raine) Cohort Study.

244 Pregnancy rates among infertile women have been reported

245 This pregnancy-related analgesia is reversible by intrathecal

246 We examined relationships between parental pregnancy-related characteristics and NAFLD in 1,170 ado

247 Examination of parental pregnancy-related characteristics may provide insights i

248 h HIV: 'Socio-demographic, Health status and Pregnancy', 'Religion and spirituality', 'Beliefs and At

249 exposure to PM2.5 during discrete periods of pregnancy results in PTB and LBW.

250 In late mouse pregnancy, rhythmicity of energy metabolism-related gene

251 During pregnancy, semiallogeneic fetal extravillous trophoblast

252 -Hcg levels, the possibility of scar ectopic pregnancy should be considered.

253 Paternal grandmothers smoking in pregnancy showed no associations.

254 and 4-hydroxyoestradiol (4-OHE2 ), stimulate pregnancy-specific proliferation of uterine artery endot

255 additional benefits to fetal growth from the pregnancy-specific ration and vitamin supplements beyond

256 was no significant additional impact of the pregnancy-specific ration and vitamin supplements.

257 (Snart Foraeldre) and North America [PRESTO (Pregnancy Study Online)] in which women completed a vali

258 KEY POINTS: Common complications of pregnancy, such as chronic fetal hypoxia, trigger a feta

259 The strong associations across pregnancies support a predominantly maternal origin of e

260 mpsia is a complex and common human-specific pregnancy syndrome associated with placental pathology.

261 re to PAHs may cause systemic changes during pregnancy that could lead to adverse pregnancy or develo

262 ells from nonpregnant donors with a previous pregnancy that was complicated by severe PE (sPE).

263 In 305 women at risk of pregnancy, the cumulative incidence of pregnancy was 106

264 In the third trimester of pregnancy, the human fetus has the capacity to process p

265 227 children whose mothers had smoked during pregnancy, the peripapillary RNFL was 5.7 mum (95% CI, 4

266 ca are attributed to P falciparum malaria in pregnancy; the population attributable fraction decrease

267 ategies that could synergize with ART during pregnancy to achieve the elimination of pediatric HIV in

268 on and expectant management (continuation of pregnancy to either spontaneous labour, induction of lab

269 accine was recommended for women during each pregnancy to protect infants in the first months of life

270 signed 325 women (215 pregnant, 110 planning pregnancy) to capillary glucose monitoring with CGM (108

271 and 43 (40%) of control participants in the pregnancy trial, and in 12 (27%) of CGM participants and

272 37%) of control participants in the planning pregnancy trial.

273 ) of 57 control participants in the planning pregnancy trial.

274 ared with urine from women with normotensive pregnancies, urine from women with preeclamptic pregnanc

275 l incompetence, preterm labor during current pregnancy, vaginitis or vulvovaginitis, and sepsis.

276 sk of pregnancy, the cumulative incidence of pregnancy was 106.0 per 1000 person-years, corresponding

277 or protein.The mean +/- SD protein intake in pregnancy was 93 +/- 15 g/d (16% +/- 3% of energy) in GD

278 ncrement in PM2.5 exposure during the entire pregnancy was associated with 8.8% (95% CI, -14.1% to -3

279 nclear.We explored whether SCB intake during pregnancy was associated with children's body mass index

280 before or after pregnancy, endoscopy during pregnancy was associated with preterm birth (ARR, 1.16)

281 Maternal smoking during pregnancy was associated with risk of TD/CTD in a dose-r

282 te measure of healthy lifestyle during early pregnancy was associated with substantially lower GDM ri

283 outcomes, whereas the use of LMWH throughout pregnancy was associated with the lowest risk of adverse

284 rent screening approaches over the course of pregnancy was limited.

285 LDL-c rate of change throughout pregnancy was positively associated with BW z-score (bet

286 dietary factors.Refined-grain intake during pregnancy was positively associated with offspring BMIZ

287 maternal interleukin-6 concentration during pregnancy was prospectively associated with larger right

288 nformation on fever and infections common in pregnancy was prospectively collected in 2 pregnancy int

289 Although pregnancy was rescued by LIF and was maintained to term

290 ding the role of the energy balance entering pregnancy.We investigated how preconceptional and gestat

291 While hyperleptinemia and pre-pregnancy weight gain were present in all db/+mice acros

292 ual period and did not switch or stop ART in pregnancy were considered to be ART exposed from concept

293 pregnancies) and levetiracetam (1.77% in 817 pregnancies) were associated with the lowest risk and va

294 egnancy is an extremely rare type of ectopic pregnancy, where there is implantation of the gestationa

295 l model of noninfectious inflammation during pregnancy, which is triggered by MSU crystals and leads

296 randomly assigned 1776 women with singleton pregnancies who were at high risk for preterm preeclamps

297 d in 9 of 85 (11%; 95% CI, 6%-19%) completed pregnancies with maternal symptoms or exposure exclusive

298 However, associations of SCB intake during pregnancy with child body composition have been unclear.

299 aternal antidepressant medication use during pregnancy with ID in offspring and investigate the impor

300 Data collectors visited each woman in pregnancy, within 72 h of her baby's birth, and at 3, 6,

301 the late second or early third trimester of pregnancy would prevent most maternal cases.