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1 ditions within 30 days of screening, or were pregnant.
2 2, 2016, we randomly assigned 325 women (215 pregnant, 110 planning pregnancy) to capillary glucose m
3   Results During follow-up, 149 women became pregnant, 131 women had live births, and 16 women had se
4 andomised controlled trial, we recruited non-pregnant adults aged at least 18 years with newly or rec
5   Specifically, peripheral ZIKV infection of pregnant AIR females resulted in detectable virus in bra
6 o capillary glucose monitoring with CGM (108 pregnant and 53 planning pregnancy) or without (107 preg
7 t and 53 planning pregnancy) or without (107 pregnant and 57 planning pregnancy).
8 et nearly a half of the RDA of vitamin A for pregnant and lactating women.
9 risk of EVD diagnosis, and mortality between pregnant and nonpregnant women.
10 60) were not significantly different between pregnant and nonpregnant women.
11 ococcus (GBS), including invasive disease in pregnant and postpartum women, fetal infection/stillbirt
12 3) rats that were allowed to mate and become pregnant and suckled their pups for 21 days before weani
13 but also on how to manage them once they are pregnant and when to refer them to a regional center wit
14 uction of systemic infection and abortion in pregnant animals and provide a viable candidate for the
15      In vivo, T-cell-specific GR deletion in pregnant animals undergoing experimental autoimmune ence
16     Given that most female cardiologists are pregnant at some point during their careers, particularl
17 clusion that for women who are or may become pregnant, avoiding alcohol is the safest option.
18 as detectable in pregnant WT mice but not in pregnant B-cell knockout dams, and antigen concentration
19                   For the first study, timed-pregnant B6C3F1 mice were exposed to concentrated ambien
20                             In this study of pregnant BALB/c mice immunized with subunit H1N1 influen
21 2) rats that were allowed to mate and become pregnant but did not suckle their pups after giving birt
22 ow that small intestine dendritic cells from pregnant, but not from non-pregnant, females secrete IL-
23 Z2 inhibits vertical transmission of ZIKV in pregnant C57BL/6 mice and protects type I or type I/II i
24 sed the timing of birth and fetal outcome in pregnant C57BL/6J mice at 3 months (young) and 5 months
25           Utilizing BPA as a model exposure, pregnant CD-1 mice were administered 25mug/kg/day BPA vi
26                                              Pregnant CGM users spent more time in target (68% vs 61%
27 viduals, the odds ratio for drug abuse while pregnant compared with an equivalent prepregnancy interv
28 perglycaemic (27% vs 32%; p=0.0279) than did pregnant control participants, with comparable severe hy
29                                              Pregnant dams were injected intraperitoneally at gestati
30                     Notably, pretreatment of pregnant dams with magnesium sulfate is sufficient to pr
31 ciency virus (HIV)-infected women who became pregnant during 2 HIV prevention studies conducted among
32 report here the case of a patient who became pregnant during treatment with ustekinumab for a refract
33 derived from pregnant (P-UAECs), but not non-pregnant ewes.
34                                         Time-pregnant female C57BL/6 mice were exposed to LG-IH or ro
35                                              Pregnant female C57BL/6J mice were exposed to cigarette
36 ll transfusions, mortality rates for an ever-pregnant female donor vs male donor were 74 vs 62 per 10
37      For receipt of transfusion from a never-pregnant female donor vs male donor, mortality rates wer
38 R, 0.99 [95% CI, 0.87 to 1.13]); for a never-pregnant female donor vs male donor, mortality rates wer
39 sions, receipt of a transfusion from an ever-pregnant female donor, compared with a male donor, was a
40  to transfusions from ever-pregnant or never-pregnant female donors was analyzed using life tables an
41 ell transfusions from ever-pregnant or never-pregnant female donors, compared with red blood cell tra
42                                              Pregnant female mice were exposed to PBS or HDM during p
43  prevalence of ID among both nonpregnant and pregnant females exist, with Mexican American and non-Hi
44                             ID prevalence in pregnant females increased significantly with each trime
45 s with first-onset or allergic sinusitis and pregnant females were excluded.
46 dritic cells from pregnant, but not from non-pregnant, females secrete IL-1beta, IL-23 and IL-6 and s
47 pregnancy outcomes, is not possible in women pregnant for the first time.
48  using a mouse model and in abortion using a pregnant guinea pig model following oral challenge.
49 shment of bacteremia in mice and abortion in pregnant guinea pigs, while complementation of capsule e
50 colleagues discuss viral load monitoring for pregnant HIV-positive women and those breastfeeding; ART
51 etary nitrate supplementation to date in non-pregnant humans and animals, current investigations aim
52       Importantly, we show that treatment of pregnant IL-10(-/-) mice with A-1254 resulted in placent
53 and can induce preeclampsia-like symptoms in pregnant IL10(-/-) mice.
54  trial at Emory University that enrolled non-pregnant, immunocompetent adults from Atlanta, GA, USA,
55 ct ZIKV inoculation into the uterine wall of pregnant, immunocompetent mice to evaluate transplacenta
56 nancy in Nsanje district, and women who were pregnant in Chikwawa district (and thus not exposed to o
57 or maternal PKU, and 120-600 mumol/L for non-pregnant individuals older than 12 years.
58  of sub-optimal iodine status especially for pregnant/lactating women.
59            Here we report the discovery of a pregnant long-necked marine reptile (Dinocephalosaurus)
60                            Participants were pregnant (</=13 weeks and 6 days' gestation) or planning
61             After a single-dose vaccination, pregnant mice challenged with Zika virus at embryonic da
62     Here we demonstrate that germ-free adult pregnant mice inoculated with a gut microbial community
63  the LPA-producing enzyme autotaxin (ATX) in pregnant mice leads to HB-EGF and COX-2 down-regulation
64 the effect of resveratrol supplementation of pregnant mice on offspring thermogenesis and energy expe
65                                              Pregnant mice that had been colonized with mouse commens
66                                              Pregnant mice were administered methionine equivalent to
67                                              Pregnant mice were orally administered 0.3 and 3 mug PFO
68                                              Pregnant mice were subjected to chronic circadian disrup
69 ected at E12, and reciprocally, treatment of pregnant mice with IFN-lambda2 reduced ZIKV infection.
70           In this paradigm, we treated timed-pregnant mice with polyinosinic:polycytidylic acid (Poly
71                                           In pregnant mice, interleukin-17a (IL-17a) produced by T he
72                                           In pregnant mice, wild-type or engineered LALA variants of
73 o enter fetal tissues and is safe for use in pregnant mice.
74       Antibiotic use in children or in their pregnant mother can affect how the intestinal microbiome
75 a moderate 30% global calorie restriction of pregnant mothers and used cardiac magnetic resonance ima
76 odevelopmental disorders in the offspring of pregnant mothers undergoing immune system activation owi
77           Overall, noninvasive management in pregnant mothers who have had a previous neonate with FN
78 ions of treating infants, or even just their pregnant mothers, with antibiotics.
79 2B expression was significantly decreased in pregnant mouse and human myometrium during labor.
80  wild-type (WT) mice were crossed to produce pregnant mouse models with or without adiponectin defici
81 ta on longitudinal changes in iron status in pregnant North American women, emphasizes possible limit
82          In addition, it has been noted that pregnant, obese women, compared with lean subjects, have
83 a mother who performed farm activities while pregnant (odds ratio, 0.60; 95% CI, 0.48-0.74) and remai
84 rds were reviewed to identify women who were pregnant or </=12 weeks postpartum at time of SCAD.
85 e at least 18 years of age, trying to become pregnant or at less than 12 weeks' gestation, not using
86 onpregnant and nonbreastfeeding women and in pregnant or breastfeeding women (OR >49.0; P < 0.001), b
87 nonbreastfeeding women compared with 0.7% of pregnant or breastfeeding women (P = 0.001).
88 onpregnant and nonbreastfeeding women and in pregnant or breastfeeding women.
89 ality and exposure to transfusions from ever-pregnant or never-pregnant female donors was analyzed us
90        Red blood cell transfusions from ever-pregnant or never-pregnant female donors, compared with
91 3000-52000) cases of invasive GBS disease in pregnant or postpartum women, and 57000 (UR, 12000-10400
92 lished data on invasive GBS disease in women pregnant or within 42 days postpartum.
93  the permeability of cervical mucus from non-pregnant ovulating (n = 20) and high- (n = 9) and low-ri
94 terine artery endothelial cells derived from pregnant (P-UAECs), but not non-pregnant ewes.
95            We ran two trials in parallel for pregnant participants and for participants planning preg
96       Also, 30 ZIKV(+) sera from symptomatic pregnant patients showed elevated levels of M2-skewed im
97 ged, carboxylated microspheres in mucus from pregnant patients was significantly restricted compared
98 tage 2 for safety and efficacy evaluation in pregnant patients.
99 -molecule Wnt agonists (Dkk inhibitors) into pregnant Pax9(+/-) mice restored Wnt signaling and led t
100        Our review of 17 cases of botulism in pregnant/postpartum women found that more than half requ
101 om a prospective study of incident HIV among pregnant/postpartum women in Kenya were randomly divided
102                     Administration of HbF to pregnant rabbits increased the number of urinary EVs of
103 ole of HbF in podocyte injury was studied in pregnant rabbits.
104 Administration of dibutyl phthalate (DBP) to pregnant rats causes reproductive disorders in male offs
105                                              Pregnant rats exposed to episodic inhaled nicotine via a
106  primary neuronal culture derived from timed pregnant rats in vitro, resulting in a much higher C99 l
107                                  Conversely, pregnant SERT (-/-) mice displayed normalized estrogen l
108                                           In pregnant sheep, experimental models with a small, defect
109 breast-conserving surgery is planned) or are pregnant should not undergo SNB.
110        Administration of CQ to ZIKV-infected pregnant SJL mice during mid-late gestation significantl
111              Restraint stress was applied to pregnant Slc6a4 (+/+) and Slc6a4 (+/-) mice and post-str
112 ical trial that vitamin C supplementation to pregnant smokers can lessen the impact of maternal smoki
113                                        Timed-pregnant Sprague-Dawley dams underwent bilateral uterine
114 l patient populations, such as pediatric and pregnant trauma patients, and the potential for future r
115 rticularly maternal farming activities while pregnant, were strongly associated with reduced risk of
116                               51.7% of women pregnant with twins reported receiving medical assistanc
117 d through the landscape for up to 50 km, the pregnant woman from Isernia was probably local, given th
118 nd month after primary infection onset in 44 pregnant women (15 transmitting the infection to the fet
119 cy.Nested within a feeding study, 24 healthy pregnant women (26-29 wk of gestation) consumed a single
120                               Thirteen of 44 pregnant women (30%) tested EVD positive; 6 of 13 (46%)
121                       We studied forty-eight pregnant women (31 healthy volunteers and 17 with fetal
122 erse obstetrical events were recorded in 953 pregnant women (4.8%).
123 r effect on preterm births among underweight pregnant women (BMI <18.5 kg/m(2); RR 0.84, 95% CI 0.78-
124        A prospective cohort study in Chinese pregnant women (n = 3220) was conducted to investigate t
125  in the UK, at 16 fetal medicine centres, of pregnant women aged 16 years or older whose fetus had a
126 crocephaly, in the foetuses and offspring of pregnant women and (b) GBS in any population, and to des
127 oven association with fetal brain defects in pregnant women and acute neurological illness.
128               In intervention clusters, more pregnant women and children attained minimum dietary div
129 nt need to develop pretest education for all pregnant women and consistent post-test management recom
130          Studies assessing infectiousness of pregnant women and gametocyte dynamics during different
131 ncluding microcephaly in fetuses of infected pregnant women and Guillian-Barre syndrome in adults.
132 rted for other general population samples of pregnant women and nonpregnant adults, was associated wi
133 umulating datasets of genomic information on pregnant women and their fetuses raise ethical issues re
134  virus causes life-threatening infections in pregnant women and their newborns.
135 ravel advisories and prevention measures for pregnant women and their partners.
136 from randomisation to 34 weeks' gestation in pregnant women and to 24 weeks or conception in women pl
137 iron supplementation of largely iron-replete pregnant women and young children (6-24 mo) in developed
138 status, current estimates of iron status for pregnant women and young children in the United States a
139 harm of iron supplementation of iron-replete pregnant women and young children.
140 ola, and Zika, are becoming more common, and pregnant women are at increased risk for associated comp
141 simetry deriving from (18)F-FDG injection in pregnant women are estimated from animal data.
142                            Moreover, data on pregnant women are limited, and thus, data on women of r
143                                              Pregnant women are particularly vulnerable to iron defic
144                                              Pregnant women are particularly vulnerable to iron defic
145                                      Because pregnant women are the main target population for ZIKV t
146   Women of reproductive age and particularly pregnant women are the most vulnerable to the adverse co
147 gnancy, and retinal microvascular changes in pregnant women at 26-28 weeks of pregnancy.
148  stage growth in vitro is reduced in anaemic pregnant women at baseline, but increased during supplem
149 rth drawn from a prospective birth cohort of pregnant women at Brigham and Women's Hospital in Boston
150                                              Pregnant women at Cairo University were screened for ant
151 hma Reduction Trial is a randomized trial of pregnant women at risk of having children with asthma ra
152 ra vaccination campaigns have often excluded pregnant women because of insufficient safety data for u
153                                 Infection of pregnant women by Asian lineage strains of Zika virus (Z
154                                          The pregnant women completed an interviewer-administered que
155  MEHP similar to those found in the urine of pregnant women consistently altered hCG and PPARgamma ex
156                                              Pregnant women cooking with kerosene or firewood were ra
157                                              Pregnant women disproportionately underreport smoking an
158 to reduce malaria transmission often exclude pregnant women due to safety concerns related to the dru
159 al care providers to provide Tdap vaccine to pregnant women during routine prenatal visits at the ear
160 alciparum pathogenesis in vitro in RBCs from pregnant women during their 2nd and 3rd trimesters.
161 strate that serum samples from dengue-immune pregnant women enhanced ZIKV infection.
162         This prospective cohort study of 913 pregnant women examined the association between high MF
163                      Thalidomide was used by pregnant women for morning sickness but was removed from
164  of HIV risk and could be used to prioritize pregnant women for PrEP.
165  with household air pollution in a cohort of pregnant women from Dar es Salaam, Tanzania.
166                                    Among 587 pregnant women from the EDEN (Etude des Determinants pre
167                            We analyzed 1,240 pregnant women from the Spanish INMA [Environment and Ch
168                        Only five (5%) of 107 pregnant women had an uneventful outcome.
169 e supplementation in mildly iodine-deficient pregnant women had no effect on child neurodevelopment a
170                            KEY POINTS: Older pregnant women have a greater risk of operative delivery
171  intakes in various populations suggest that pregnant women have difficulty meeting all their nutriti
172 immunodeficiency virus research field, where pregnant women have enjoyed better-although imperfect-re
173 ion and one of two on offering disadvantaged pregnant women help to quit smoking that reported on our
174                            Participants were pregnant women identified and recruited in the study clu
175  human immunodeficiency virus (HIV)-infected pregnant women in Africa.
176  (DP) to daily TMP-SMX alone in HIV-infected pregnant women in an area of Uganda where indoor residua
177 lined substantially in the 21st century, but pregnant women in areas of sustained transmission still
178 n this randomised, placebo-controlled trial, pregnant women in Bangalore, India, and Bangkok, Thailan
179 dies, support use of oral cholera vaccine in pregnant women in cholera-affected regions.
180 ed micronutrient supplementation trial among pregnant women in Dar es Salaam, Tanzania (2001-2004).
181 cific serodiagnostic tests, particularly for pregnant women in dengue virus (DENV)-endemic regions.
182 ve on the risk/benefit tradeoff of including pregnant women in research to address different forms of
183  a community perspective on the inclusion of pregnant women in TB drug research and discuss (1) our p
184 magnetic resonance imaging (MRI) findings in pregnant women in the Department of Diagnostic Imaging,
185  PHIV vs nonperinatally HIV-infected (NPHIV) pregnant women in the Pediatric HIV/AIDS Cohort Study Su
186 cent years, short-term antiviral therapy for pregnant women in the third trimester has been shown to
187                                  A cohort of pregnant women in their early third trimester (n = 81) w
188                                        Among pregnant women in Washington State, low and high prepreg
189 tachment intervention targeting impoverished pregnant women increased more than 2.5-fold when only sh
190 desh, we randomized geographical clusters of pregnant women into individual water treatment, sanitati
191 hain reaction screening of T. cruzi-infected pregnant women is a useful tool for predicting the risk
192 on approaches may reduce DDT/DDE exposure in pregnant women living in IRS communities.
193 d appropriate treatment of hypothyroidism in pregnant women may be an area for possible prevention of
194                                     However, pregnant women might represent an important source of hu
195                                   In Malawi, pregnant women of any gravidity status were tested at ea
196 e supplementation in mildly iodine-deficient pregnant women on neurodevelopment of their offspring in
197  rhPAPPA and PAPPA in the serum samples from pregnant women or conditioned medium of trophoblast cell
198 ematologic indexes in otherwise asymptomatic pregnant women or in infants within populations who are
199                                      Care of pregnant women or new mothers with botulism can include
200                                              Pregnant women or patients who needed urgent medical att
201 o recommend routine iron supplementation for pregnant women or routine screening for iron deficiency
202 tine screening for iron deficiency anemia in pregnant women or young children.
203 uman immunodeficiency virus (HIV)-uninfected pregnant women protected by indoor residual spraying of
204 ng anthropometry for moderately malnourished pregnant women receiving ready-to-use supplemental food
205                                 HIV-infected pregnant women receiving rilpivirine 25 mg once daily we
206                    3001 infants were born to pregnant women recruited between Oct 1, 2013, and Feb 10
207                              Since 2007, all pregnant women referred to give birth at Hvidovre Hospit
208 rformed a prospective observational study of pregnant women referred to our maternal-fetal medicine d
209 inical need for TB prevention and treatment, pregnant women remain neglected by research initiatives.
210 ity; however, influenza vaccination rates of pregnant women remain under 50%.
211 ngle-center, nonblinded study among selected pregnant women require confirmation in multicenter clini
212       Importantly, infection of the blood of pregnant women revealed an enhanced susceptibility to ZI
213                                              Pregnant women show less symptoms of TMDs than that of n
214  cohort with essentially complete follow-up, pregnant women taking supplemental folic acid at or abov
215 randomized 720 geographical clusters of 5551 pregnant women to a control or an intervention arm.
216       To do nothing would allow thousands of pregnant women to expose their fetuses to an infection t
217  20) and high- (n = 9) and low-risk (n = 16) pregnant women to probes of varying sizes and surface ch
218 s abortion, death, and congenital defects in pregnant women treated with any of the following: 1) a v
219      We found a small difference in HbA1c in pregnant women using CGM (mean difference -0.19%; 95% CI
220         A prospective cohort of 635 Beninese pregnant women was recruited before 24 weeks of gestatio
221                               A total of 239 pregnant women were enrolled; 32 blood samples (13.4%) w
222                                              Pregnant women were excluded.
223                                              Pregnant women were less likely than nonpregnant women t
224 al Asthma Reduction Trial (VDAART), in which pregnant women were randomly assigned to vitamin D suppl
225                                              Pregnant women were recruited between 2003 and 2008.
226 s (PASTURE) is a European birth cohort where pregnant women were recruited between August 2002 and Ma
227                        131 ZIKV-PCR positive pregnant women were scored for clinical disease severity
228  interventions, including drug treatment, in pregnant women who are obese or overweight have not had
229 revent or significantly attenuate viremia in pregnant women who are residents of or travelers to epid
230 ernative treatment option for HIV-1-infected pregnant women who are virologically suppressed, in sett
231                    These patients included 6 pregnant women who later delivered during the course of
232          We report fetal outcomes for 1 of 4 pregnant women who participated in an observational stud
233 mpaign in Tororo, Uganda, among HIV-infected pregnant women who received bed nets, daily trimethoprim
234 d a prospective cohort study in Zambia among pregnant women who received intermittent preventive trea
235                      Moreover, we included 2 pregnant women who underwent fetal MRI and had incidenta
236                           The study enrolled pregnant women who visited the outpatient clinic for ant
237                                    Including pregnant women will increase intervention coverage and i
238 were drawn from a cohort whose partners were pregnant women with a due date between April 25, 2009, a
239 stigated the prevalence of bacteriuria among pregnant women with and without UTI symptoms in Uganda.
240 STF recommends screening for preeclampsia in pregnant women with blood pressure measurements througho
241 monitoring decisions and risk assessment for pregnant women with CHD at the time of delivery.
242                                        While pregnant women with confirmed EVD had similar Ebola vira
243 associated with an improved birth outcome in pregnant women with documented PAM.
244  the risk of venous thromboembolism (VTE) in pregnant women with essential thrombocythemia.
245   Limited data were available in infants and pregnant women with malaria as well as in healthy indivi
246                                              Pregnant women with malnutrition and malaria infection a
247  was conducted in southern Malawi among 1828 pregnant women with moderate malnutrition, defined as a
248 evels in the amniotic fluid of ZIKV-positive pregnant women with neonatal microcephaly.
249                        Thyroid antibodies in pregnant women with normal functioning thyroids (ie, eut
250 c pathways in murine models and samples from pregnant women with normally grown and large-for-gestati
251 rtain if HCMV DNA in the peripheral blood of pregnant women with primary HCMV infection at the time o
252 CMV-specific T cells by cultured ELISPOT, in pregnant women with primary HCMV infection, in associati
253                                           In pregnant women with primary infection, the cultured ELIS
254 ansmitting the infection to the fetus) and 8 pregnant women with remote infection.
255    Subsequently, eligibility was expanded to pregnant women with sexual partners with similar travel
256                              A total of 1136 pregnant women with singleton pregnancies were recruited
257                                              Pregnant women with suspected EVD had the same risk, how
258 rt a difference in the risk of death between pregnant women with suspected or confirmed EVD compared
259                 CGM should be offered to all pregnant women with type 1 diabetes using intensive insu
260   The prevalence of culture-proven UTI among pregnant women with UTI symptoms was 4%.
261      No therapeutic options are available to pregnant women with ZIKV infection to prevent these effe
262  and serotype distribution of GBS colonizing pregnant women worldwide.
263 pecifically, Asian-lineage ZIKV infection of pregnant women's blood led to an exacerbated M2-skewed i
264  Among 56 IPT-DP recipients (26 children, 30 pregnant women) with cardiac parameters, all QTc interva
265  in children younger than 5 years and one in pregnant women), and nine IPT trials (five in children y
266 one in schoolchildren, one in adults, two in pregnant women).
267                                     Of the 4 pregnant women, 1 gave birth to a healthy infant, 2 had
268                         Among 1,151 enrolled pregnant women, 172 (15% [95% confidence interval [CI],
269 ects of CQ, its lack of contraindications in pregnant women, and its worldwide availability and low c
270  via Asia, it has become a serious threat to pregnant women, causing microcephaly and other neuropath
271 ing point for scaling up, given its reach to pregnant women, families, and young children.
272        The risk of EOGBS among GBS-colonized pregnant women, from this first systematic review, is co
273 egies (targeting vaccination for infants, or pregnant women, or prophylactic antibodies for neonates)
274  in New York State for symptomatic patients, pregnant women, their infants, and patients with Guillai
275 togenes causes foodborne systemic disease in pregnant women, which can lead to preterm labor, stillbi
276 icantly different between high- and low-risk pregnant women.
277 should focus on maximizing Tdap uptake among pregnant women.
278 ia is used in infants, children, adults, and pregnant women.
279 ing total 25(OH)D in a prospective cohort of pregnant women.
280 rch studies of iron status in North American pregnant women.
281 cancers, and can be detected in the blood of pregnant women.
282 ve study involving 144 T. cruzi seropositive pregnant women.
283 een PFAS exposures and metabolic outcomes in pregnant women.
284  common neutrophil signature in males and in pregnant women.
285  show less symptoms of TMDs than that of non-pregnant women.
286 rticles, 85 countries, and a total of 299924 pregnant women.
287 ality, particularly among young children and pregnant women.
288 nformation including baseline iron stores in pregnant women.
289 ion of these, and is present in up to 18% of pregnant women.
290 net benefit of screening for preeclampsia in pregnant women.
291 acid versus iron-folic acid alone in 112 953 pregnant women.
292  (CO) over 72 hr among a cohort of Tanzanian pregnant women.
293 1, 2013, and Dec 31, 2015, we recruited 5781 pregnant women.
294 nce imaging is the best imaging modality for pregnant women.
295 r infants born to undernourished and anaemic pregnant women.
296 tions should also aim to reduce exposures to pregnant women.
297 obal health problem, affecting almost 50% of pregnant women.
298 d on levels found previously in the urine of pregnant women: mono-n-butyl (MnBP, 200 nM), monobenzyl
299 B compared with term birth in two cohorts of pregnant women: one predominantly Caucasian (n = 39) at
300 lacentar allergen transfer was detectable in pregnant WT mice but not in pregnant B-cell knockout dam

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